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Boc-γ-L-Ser(Bn)-PNA-C(Z)-OH
Boc-γ-L-Ser(Bn)-PNA-C(Z)-OH is an innovative biomedical compound, functioning as a peptide nucleic acid (PNA) monomer. This compound proves efficacious in gene therapy and the development of antisense drugs. Alternative Names: Boc-Gamma-L-Ser(Bn)-PNA-C(Cbz)-OH; Glycine, N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-N-[[2-oxo-4-[[(phenylmethoxy)carbonyl]amino]-1(2H)-pyrimidinyl]acetyl]-. CAS No. 909867-00-1. Molecular formula: C31H37N5O9. Mole weight: 623.66.
Boc-γ-L-Ser(Bn)-PNA-G(Z)-OH
Boc-γ-L-Ser(Bn)-PNA-G(Z)-OH is an indispensable element in the biomedical realm, usecd in the study of maladies and contagions. Alternative Names: Boc-Gamma-L-Ser(Bn)-PNA-G(Cbz)-OH; Glycine, N-[[1,6-dihydro-6-oxo-2-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-. CAS No. 909866-99-5. Molecular formula: C32H37N7O9. Mole weight: 663.69.
Boc-γ-L-Ser(Bn)-PNA-T-OH
Boc-γ-L-Ser(Bn)-PNA-T-OH is a biomedical compound, facilitating the development and adaptation of personalized oncological remedies, genetic disorder research and infectious ailment conques. Alternative Names: Boc-Gamma-L-Ser(Bn)-PNA-T-OH; Glycine, N-[[3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl]acetyl]-N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-. CAS No. 909866-98-4. Molecular formula: C24H32N4O8. Mole weight: 504.54.
BOC-GLY-LYS-ARG-MCA
BOC-GLY-LYS-ARG-MCA. Alternative Names: T-BUTYLOXYCARBONYLGLYCYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE; BOC-GLY-LYS-ARG-MCA. Grades: 95%. CAS No. 109358-48-7. Molecular formula: C29H44N8O7. Mole weight: 616.71.
Bocidelpar
A modulator of peroxisome proliferator-activated receptor delta (PPAR-δ) that improves mitochondrial function. Alternative Names: ASP0367; MA-0211; Hexanoic acid, 3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-, (3R)-. Grades: 98%. CAS No. 2095128-20-2. Molecular formula: C25H27F3N2O3. Mole weight: 460.49.
Bococizumab is a humanized monoclonal antibody binding to proprotein convertase subtilisin / kexin type 9 (PCSK9), which reduces LDL cholesterol (LDL-C) levels. Bococizumab may be used as a potential drug for the treatment of hypercholesterolemia. Alternative Names: PF-04950615; PF 04950615; PF04950615. CAS No. 1407495-02-6.
BOC-PRO-LEU-VAL-OME
BOC-PRO-LEU-VAL-OME. Alternative Names: BOC-PRO-LEU-VAL-OME. Grades: 95%. CAS No. 13650-75-4. Molecular formula: C22H39N3O6. Mole weight: 441.56.
Boc-Saxagliptin
An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Alternative Names: N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-Carbamic Acid 1,1-Dimethylethyl Ester; Saxagliptin Impurity 16. Grades: > 95%. CAS No. 709031-43-6. Molecular formula: C23H33N3O4. Mole weight: 415.54.
Boc-Valine,NCA
Boc-Valine,NCA. Alternative Names: tert-butyl(4S)-2,5-dioxo-4-propan-2-yl-1,3-oxazolidine-3-carboxylate; 141468-55-5; Boc-Valine,NCA; Boc-L-Val-NCA; BOC-VAL-NCA; SCHEMBL2132635. Grades: 95%. CAS No. 141468-55-5. Molecular formula: C11H17NO5. Mole weight: 243.25638.
BODIPY 406/444
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. CAS No. 1309918-21-5. Molecular formula: C9H8BF2N3. Mole weight: 206.991.
BODIPY 493/503
BODIPY 493/503 is a fluorescent probe for labeling cellular neutral lipid contents in live and fixed cells. BODIPY 493/503 has been used in epifluorescent, confocal, two-photon microscopy, and flow cytometry. Alternative Names: BDP 493/503 lipid stain;Pyrromethene 546; 1,3,5,7,8-Pentamethyl-BODIPY; (T-4)-[2-[1-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)ethyl]-3,5-dimethyl-1H-pyrrolato-κN]difluoro-boron. Grades: ≥98%. CAS No. 121207-31-6. Molecular formula: C14H17BF2N2. Mole weight: 262.1.
BODIPY 558/568 C12
BODIPY 558/568 C12 is an orange-fluorescent fatty acid that can be used as a building block in the synthesis of various fluorescent phospholipids or other lipophilic probes. It has been used to create bioconjugates with peptides, proteins, modified nucleotides and biopolymers with amine groups using a carbodiimide like EDAC or DIPC. Alternative Names: 4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoic Acid. CAS No. 158757-84-7. Molecular formula: C25H31BF2N2O2S. Mole weight: 472.4.
Bodipy C12-Ceramide
BODIPY-C12 Ceramide (B12Cer) is a C12 ceramide that is tagged with the fluorophore BODIPY. It is produced from the hydrolysis of BODIPY-C12 sphingomyelin by acid sphingomyelinase and is useful for quantification of acid sphingomyelinase activity in plasma from patients with Niemann-Pick disease. Alternative Names: BODIPY-C12 Ceramide;N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosine; N-[11-(TopFluor)undecanoyl]-D-erythro-sphingosine; C11 TopFluor® Ceramide. Grades: ≥98%. CAS No. 1246355-58-7. Molecular formula: C42H70N3O3F2. Mole weight: 713.83.
BODIPY-Cholesterol
BODIPY-cholesterol is a cell-permeable analog of cholesterol that is tagged with BODIPY group. BODIPY-cholesterol mimics the membrane partitioning and trafficking of cholesterol, and it is often used to study the sterol distribution and transport in living cells. Alternative Names: TopFluor Cholesterol; BCh2; (T-4)-[(3β)-24-(3,5-dimethyl-1H-pyrrol-2-yl-κN)-24-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)chol-5-en-3-olato]difluoro-boron. Grades: ≥98%. CAS No. 878557-19-8. Molecular formula: C36H51BF2N2O. Mole weight: 576.61.
BODIPY Fl C5-Ceramide
BODIPY FL C5-Ceramide is a green-fluorescent membrane probe for staining the Golgi apparatus in live cells. It is used for investigation of inhibition of glycoprotein transport by ceramide therapeutics, sphingolipid distribution kinetics, and the intracellular trafficking and targeting of thrombin receptors. Alternative Names: EverFluor FL C5-Ceramide; N-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Pentanoyl)Sphingosine. CAS No. 133867-53-5. Molecular formula: C34H54BN3O3. Mole weight: 601.62.
BODIPY FL C5-HPC
BODIPY FL C5-HPC is a green-fluorescent probe for labeling lipid membrane. This probe has been used for investigations of the uptake of antineoplastic ether lipids and for the characterization of lipid domains by microscopy. It is relatively insensitive to environment and pH changes. Alternative Names: EverFluor FL C5-HPC. Molecular formula: C40H67BF2N3O8P. Mole weight: 797.76.
BODIPY FL EDA
BODIPY FL EDA is an aliphatic-amine analog of the green-fluorescen dye, of which the primary amine can be coupled to aldehydes and ketones to yield a reversible Schiff Base product that can be transformed to a stable amine derivative using a reducing agent like sodium borohydride or sodium cyanoborohydride. Alternative Names: EverFluor FL EDA; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Propionyl Ethylenediamine Hydrochloride. Molecular formula: C16H22BF2ClN4O. Mole weight: 370.64.
BODIPY FL Glibenclamide
BODIPY FL Glibenclamide is cell-permeant dye that accumulates in the endoplasmic reticulum (ER) of living cells. It has been used for staining ER and also detecting sulfonylurea receptors related to ATP-dependent potassium channels. Alternative Names: ER-Hunt Green; EverFluor FL Glibenclamide. Molecular formula: C37H42BClF2N6O6S. Mole weight: 783.09.
BODIPY FL Histamine
BODIPY FL Histamine is a cell-permeant, green-fluorescent dye that accumulates in acidic organelles of living cells. It has been used to label and track acidic organelles of living cells, and also used to investigate binding kinetics for the four histamine receptor subtypes by flow cytometry. This probe is relatively insensitive to environment and pH changes. Alternative Names: EverFluor FL Histamine. Molecular formula: C19H22BF2N5O. Mole weight: 385.22.
BODIPY FL L-Cystine
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. The cystine disulfide is reversibly reactive with various thiol-containing biomolecules, and this compound yields a mixed disulfide fluorescent product. It is relatively insensitive to environment and pH changes. Alternative Names: EverFluor FL L-Cystine. Molecular formula: C34H38B2F4N6O6S2. Mole weight: 788.44.
BODIPY FL PEG3-Azide
BODIPY FL PEG3-Azide is a green-fluorescent dye that is reactive with alkyne using the copper-catalyzed click reaction. BODIPY FL PEG3 dye is non-ionic, and relatively insensitive to environment and pH changes. The PEG-3 linker reduces interactions of the dye and the biomolecule to which it has reacted. Alternative Names: EverFluor FL PEG3-Azide. Molecular formula: C22H31BF2N6O4. Mole weight: 492.33.
BODIPY FL Penicillin
BODIPY FL Penicillin is a conjugation of the green-fluorescent dye and the antibiotic penicillin for investigations of bacterial penicillin binding proteins (PBPs). PBPs are membrane-bound enzymes and targets of β-lactam antibiotics. BODIPY FL Penicillin has been utilized to study the mechanisms of bacterial resistance to β-lactam antibiotics. Alternative Names: EverFluor FL Penicillin. Molecular formula: C30H31BF2N5NaO6S. Mole weight: 661.46.
BODIPY FL, STP Ester, Sodium Salt
BODIPY FL, STP Ester, Sodium Salt is a green-fluorescent dye that is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers and other amine-containing biomolecules. The water solubility is improved by STP ester compared to NHS esters. Alternative Names: EverFluor FL, STP Ester, Sodium Salt. Molecular formula: C20H14BF6N2NaO5S. Mole weight: 542.19.
BODIPY FL Thapsigargin
BODIPY FL Thapsigargin is a cell-permeant, green-fluorescent probe used for investigation of thapsigargin binding sites in live cells. Thapsigargin is a potent inhibitor of plasma membrane Ca2+ ATPases and is classified as sesquiterpene lactone. Thapsigargin inhibits the ability of cell to pump calcium into the sarcoplasmic and endoplasmic reticula, resulting in an increase of intracellular calcium concentration. Alternative Names: EverFluor FL Thapsigargin. CAS No. 216571-99-2. Molecular formula: C44H57BF2N2O12. Mole weight: 854.74.
BODIPY Green 8-P2M
BODIPY Green 8-P2M is a thiol-reactive, green-fluorescent dye, and it is relatively selective for reaction with thiol groups when reacted at pH below 7.5. Alternative Names: CellHunt Green 8-P2M. CAS No. 929679-22-1. Molecular formula: C23H20BF2N3O2. Mole weight: 419.23.
BODIPY TR Cadaverine
BODIPY TR Cadaverine is an aliphatic-amine analog of the red-fluorescent dye, of which the primary amine can be coupled to aldehydes and ketones to yield a reversible Schiff Base product that can be transformed to a stable amine derivative using a reducing agent like sodium borohydride or sodium cyanoborohydride. Alternative Names: EverFluor TR Cadaverine; 5-(((4-(4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-yl)phenoxy)acetyl)amino)pentylamine Hydrochloride. CAS No. 217190-24-4. Molecular formula: C26H28BClF2N4O2S. Mole weight: 544.86.
Boehmite
Boehmite is used in the pharmaceutical industry as an excipient in drug formulations, particularly in antacid medications. It is also utilized in the treatment of inflammatory conditions such as arthritis due to its anti-inflammatory properties. Alternative Names: Aluminum oxide hydroxide. Grades: 98%. CAS No. 1318-23-6. Molecular formula: AlHO2. Mole weight: 59.99.
Boehmite (Al2O3.H2O)
Boehmite (Al2O3.H2O). Alternative Names: BIS(ALO(OH)). CAS No. 12428-54-5. Molecular formula: Al2O3.H2O. Mole weight: 119.98.
Boeravinone A
Boeravinone A is a flavonoid isolated from Boerhavia diffusa L. Alternative Names: boeravinone A; 114567-33-8; 9,11-dihydroxy-6-methoxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one; 6a,12a-Dehydro-9,11-dihydroxy-6-methoxy-10-methylrotenone; CHEMBL223681; SCHEMBL3321069; CHEBI:185205; EX-A3790; HY-N8597; BDBM50492737; LMPK12060074; AKOS040760845; CS-0148688. Grades: 0.98. CAS No. 114567-33-8. Molecular formula: C18H14O6. Mole weight: 326.3.
Bone black
Bone black. CAS No. 8021-99-6. Molecular formula: C.
BONE OIL
BONE OIL. Alternative Names: animal oil; Boneoilordippel'soil; dippel'soil; oilofhartshorn. CAS No. 8001-85-2.
Zinc borate appears as a white powder of variable composition. (typically 45% ZnO, 34% B2O3 and 20% H2O). Slightly soluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It is used as a fungus and mildew inhibitor, to fire proof textiles, and for other uses.;DryPowder; OtherSolid; PelletsLargeCrystals. Alternative Names: ZB 500; A 16536; A-ZB 400; ADK Stab M 2335; Alcanex FR 100; Alcanex FR 50; Alcanex FRC 600; Alcanex FRF 30; Alcanex XF 100C; Bonrex FC; Climax ZB 467; Estone ZB; Estone ZB 03; Firebrake ZB 500; Firebrake ZB-XF; Flacavon 275; Flamtard Z 10; FR 080; FR 50; FRC 600; HT 207; JS 9502; PSX 0060; RN-BZ 25; SN 303; SN 303 (borate); ST-FS 2300FB; Storflam ZB 2335; SZB 2335; SZB 500; XPI 187; YT 1201; ZB 03; ZB 112; ZB 2300; ZB 2325; ZB 237; ZB 467 Lite; ZB 503; ZB-XF; ZBS-DI 100; Zinc borate; Zincborel Fine; Zinflam ZB; ZN 100; ZSB 2335; ZT; ZT (fire retardant). CAS No. 1332-07-6.
bornane
bornane. Alternative Names: 1,7,7-Trimethylbicyclo[2.2.1]heptane. Grades: 95%. CAS No. 464-15-3. Molecular formula: C10H18. Mole weight: 138.25.
Bornyl acetate
Bornyl acetate is a naturally occurring compound abundant in essential oils with inherent anti-inflammatory properties. It aids in studying various inflammatory ailments, such as arthritis. Alternative Names: 1,7,7-Trimethylbicyclo(2.2.1)heptan-2-ol acetate; 1,7,7-Trimethylbicyclo(2.2.1)heptan-2-yl acetate, endo-; 2-Camphanol acetate. Grades: >98%. CAS No. 76-49-3. Molecular formula: C12H20O2. Mole weight: 196.29.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. CAS No. 1073151-44-6. Molecular formula: C36H34BF2N3. Mole weight: 557.494.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. CAS No. 1276066-58-0. Molecular formula: C30H22BF2N3. Mole weight: 473.333.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. CAS No. 1020539-60-9. Molecular formula: C41H27BF2N2. Mole weight: 596.487.
Bortezomib Impurity 10 is an impurity of bortezomib, a drug used in the biomedical industry for therapy purposes. Bortezomib is a potent anticancer drug mainly used in the therapy of multiple myeloma. Alternative Names: 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-. Grades: > 95%. CAS No. 390800-88-1. Molecular formula: C57H69B3N12O9. Mole weight: 1098.69.
Bortezomib Impurity 12
Bortezomib Impurity 12 is an impurity of Bortezomib. Alternative Names: (R)-Hydroperoxy Des(boric Acid) Bortezomib; N-((S)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-. Grades: > 95%. CAS No. 886979-78-8. Molecular formula: C19H24N4O4. Mole weight: 372.43.
Bortezomib Impurity 13
Bortezomib Impurity 13 is an impurity of Bortezomib, a pharmaceutical agent primarily indicated in the therapy of multiple myeloma and mantle cell lymphoma. Alternative Names: 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-; N-((S)-1-(((S)-1-hydroperoxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grades: > 95%. CAS No. 886979-81-3. Molecular formula: C19H24N4O4. Mole weight: 372.43.
Bortezomib Impurity (R,S-Isomer)
Bortezomib Impurity (R,S-Isomer) is a diastereomer of Bortezomib. Alternative Names: (1S,2R)-Bortezomib; B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride. Grades: > 95%. CAS No. 1132709-16-0. Molecular formula: C19H25BN4O4. Mole weight: 384.25.
Boscalid
Boscalid is a fungicide belonging to the class of carboxamides. It has been used in agriculture to protect crops. Alternative Names: Nicobifen; Endura. CAS No. 188425-85-6. Molecular formula: C18H12Cl2N2O. Mole weight: 343.21.
Bosutinib
Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively. Alternative Names: 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosulif; KIN 001-160; SK 606; SKI 606; SKI606; SK-I606. Grades: >98%. CAS No. 380843-75-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.45.
BOTRYOCOCCANE C32-C34
BOTRYOCOCCANE C32-C34. Alternative Names: BOTRYOCOCCANE C32-C34. Grades: 95%. CAS No. 76060-38-3. Molecular formula: C99H204. Mole weight: 1394.68.
BPMPO
BPMPO. Alternative Names: N,N'-Bis(5-methyl-2-biphenylyl)ethanediamide; Ethanediamide, N1,N2-bis(5-methyl[1,1'-biphenyl]-2-yl)-. Grades: >98%. CAS No. 1809289-04-0. Molecular formula: C28H24N2O2. Mole weight: 420.5.
BPTES
BPTES is a potent and selective Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM. Grades: 98%. CAS No. 314045-39-1. Molecular formula: C24H24N6O2S3. Mole weight: 524.68.
Brain Extract Total
Brain Extract Polar comprises phosphatidylethanolamine as major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol. Brain lipid, especially the polar fraction plays a key role in the inhibition of prion seeded amyloid formation. Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes. Alternative Names: Brain Total Lipid Extract (Porcine). Grades: >99%. CAS No. 86088-88-2.
Brain PE
Phosphatidylethanolamine, also known as Brain PE, is a phospholipid compound recognized for its positive impact on cognitive processes. Recent research suggests its promising potential in the management of degenerative neurological conditions and amnesia-related issues. Alternative Names: L-α-phosphatidylethanolamine (Brain, Porcine). Grades: >99%. CAS No. 383907-18-4. Molecular formula: C41H80NO8P. Mole weight: 746.05.
Brain PI(4,5)P2 (ammonium salt)
PIP2 is a component of membrane-bound receptors associated with PLC (phospholipase C). PIP2 is an activator of PKC (protein kinase C) in the presence of calcium ions phosphatidylserine. It potently stimulates brain PLD (phospholipase D) activity in vitro. Alternative Names: L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt); 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt). Grades: >99%. CAS No. 383907-42-4. Molecular formula: C47H94N3O19P3. Mole weight: 1098.18.
Brain PS
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-11% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. Alternative Names: PS (brain, porcine) 95%; L-α-Phosphatidylserine (brain, porcine) 95%. Grades: >96%. CAS No. 383907-32-2. Molecular formula: C42H79NNaO10P. Mole weight: 824.966.
Brassicasterol
A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. Brassicasterol can increase accumulation of demosterol, a cholesterol precursor and substrate and inhibit cholesterol formation in HL-60 cells in a dose-dependent manner. It also inhibits the hemolytic activity of pneumolysin from S. pneumoniae. Alternative Names: (3β,22E)-Ergosta-5,22-dien-3-ol; 24-Methylcholesta-5,22-dien-3β-ol; Brassicasterin; Ergosta-5,22(E)-dien-3β-ol. Grades: ≥95%. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66.
Brassinin
Brassinin is an inhibitor of indoleamine 2,3-dioxygenase (IDO; Ki = 28 μM for human IDO) with antifungal and anticancer activities. Brassinin also inhibits IL-6-inducible STAT3 activation and attenuates tumor growth in a xenograft lung cancer mouse model. Brassinin is found in brassicas. Alternative Names: Brassinine; CCG-208623; CCG208623; CCG 208623; HE-005916; HE005916; HE 005916; HE-292778; HE292778; HE292778; Methyl (1H-indol-3-ylmethyl)carbamodithioate. Grades: 98%. CAS No. 105748-59-2. Molecular formula: C11H12N2S2. Mole weight: 236.36.
BRD0705
BRD0705 is a potent, paralog selective and orally active inhibitor of Glycogen synthase kinase 3α (GSK3α) with IC50 of 66 nM and Kd of 4.8 μM. Alternative Names: BRD 0705; BRD-0705. CAS No. 2056261-41-5. Molecular formula: C20H23N3O. Mole weight: 321.42.
Brecanavir
Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Uses: Hiv-1 protease inhibitor. Alternative Names: Brecanavir; UNII-E367I8C7FI; CHEMBL206031; GW-0385; GW-640385; GW-640385X; VX-385; GW0385; GW640385; GW640385X; VX385; GW 0385; GW 640385; GW 640385X; VX 385; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Grades: ≥98%. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82.
Brevetoxin PbTx-3
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis. A ciguatoxin comprising a linear sequence of ten trans-fused five-, six-, eight- and nine-membered rings. Alternative Names: Brevetoxin 3; Brevetoxin T17; Dihydrobrevetoxin B; Brevetoxin PbTx 3; GB 3 toxin; T17 toxin; T-17 toxin; PbTx 3; Toxin T-17; Ptychodiscus brevis toxin 3; GB 3; 42-Deoxo-42-hydroxybrevetoxin B; Brevetoxin B, 42-deoxo-42-hydroxy-. Grades: 95 % (HPLC). CAS No. 85079-48-7. Molecular formula: C50H72O14. Mole weight: 897.11.
Brexpiprazole
Brexpiprazole is a novel atypical antipsychotic drug. It is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). It is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Uses: Brexpiprazole is approved for the treatment of schizophrenia, and as an adjunctive treatment for depression. it is a drug candidate useful in treatment and prevention of mental disorders including cns disorders. Alternative Names: 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one; OPC 34712. Grades: > 95%. CAS No. 913611-97-9. Molecular formula: C25H27N3O2S. Mole weight: 433.58.