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MK-0731
MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP. Uses: Potential antineoplastic agent. Alternative Names: ALR-3456; ALR 3456; ALR3456; 845256-65-7; MK0731, MK-0731, MK 0731; UNII-8HIJ5G3O02; 8HIJ5G3O02. CAS No. 845256-65-7. Molecular formula: C25H28F3N3O2. Mole weight: 459.513.
MK-0752
MK 0752 is a potent and reversible inhibitor of γ-secretase (IC50 ~50 nM). It was shown to reduce the number of breast cancer stem cells in tumorgrafts. Uses: Gamma secretase inhibitors and modulators. Alternative Names: Cyclohexanepropanoic acid, 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-, cis-; cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid; MK 0752; MK0752. Grades: >98%. CAS No. 471905-41-6. Molecular formula: C21H21ClF2O4S. Mole weight: 442.91.
MK-0752 sodium salt
MK-0752 sodium salt is a novel potent γ-secretase inhibitor. It is in clinical trial for treatment of several types of cancer. Uses: Mk-0752 sodium salt is used for treatment of several types of cancer. Alternative Names: MK0752; MK 0752; MK-0752; MK0752 sodium salt;Sodium 3-(4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoate. Grades: 98%. CAS No. 656810-87-6. Molecular formula: C21H20ClF2NaO4S. Mole weight: 464.88.
MK-2 Dye
MK-2 Dye. Alternative Names: 2-Cyano-3-[5-(9-ethyl-9H-carbazol-3-yl)-3,3,3,4-tetra-n-hexyl-[2,2,5,2,5,2]-quater thiophen-5-yl] acrylic acid, metal free solar cell dye. Grades: 95%. CAS No. 1037440-21-3. Molecular formula: C58H70N2O2S4. Mole weight: 955.45.
MK-3903
MK-3903 is a potent and selective AMPK activator with EC50 value of 8 nM. Alternative Names: MK 3903; MK3903; 5-[[6-Chloro-5-(4-phenylphenyl)-1H-benzimidazol-2-yl]oxy]-2-methylbenzoic acid. CAS No. 1219737-12-8. Molecular formula: C27H19ClN2O3. Mole weight: 454.90.
MK-467
MK-467 is a peripheral Alpha2 -adrenoceptor antagonist originated by Merck & Co. It can dose-dependently attenuate the bradycardia associated with dexmedetomidine, and shorten the sedative effect without altering its quality. Clinical for Diabetes mellitus in USA was discontinued in 1994. Uses: Diabetes mellitus. Alternative Names: MK-467; MK 467; MK467; UNII-66932R910R; N-(2-((2R,12bS)-2'-oxo-1,3,4,6,7,12b-hexahydrospiro[benzofuro[2,3-a]quinolizine-2,4'-imidazolidin]-3'-yl)ethyl)methanesulfonamide hydrochloride. Grades: 98%. CAS No. 130466-38-5. Molecular formula: C20H27ClN4O4S. Mole weight: 454.98.
MK-4827
MK-4827 HCl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. It has a great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1. Uses: Poly(adp-ribose) polymerase inhibitors. Alternative Names: 2H-Indazole-7-carboxamide, 2-[4-(3S)-3-piperidinylphenyl]-, hydrochloride (1:1); MK4827; MK 4827; Niraparib monohydrochloride; Niraparib HCl; Niraparib hydrochloride; 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide hydrochloride (1:1); (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride; 2H-Indazole-7-carboxamide 2-[4-(3S)-3-piperidinylphenyl]-, monohydrochloride; MK 2512. Grades: >98%. CAS No. 1038915-64-8. Molecular formula: C19H21ClN4O. Mole weight: 356.85.
MK-4827 tosylate
MK-4827 tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. It has a great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1. Alternative Names: (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate; MK-4827; MK-4827; MK4827; MK4827-tosylate; Niraparib tosylate. Grades: >98%. CAS No. 1038915-73-9. Molecular formula: C26H28N4O4S. Mole weight: 492.59.
MK-6892
MK-6892 is a highly potential GPR109A agonist. Alternative Names: MK6892; MK 6892; MK-6892. Grades: >98%. CAS No. 917910-45-3. Molecular formula: C19H22N4O5. Mole weight: 386.4.
ML130
ML130 (Nodinitib-1) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2. Alternative Names: ML 130; ML-130; Nodinitib-1; Noditinib-1; 1-Tosyl-1H-benzo[d]imidazol-2-amine. Grades: >98%. CAS No. 799264-47-4. Molecular formula: C14H13N3O2S. Mole weight: 287.34.
ML 334
ML 334 is an inhibitor of Keap1-Nrf2 interaction. It can affect the cytoprotective responses to oxidative and electrophilic stress. Alternative Names: ML 334; ML334; ML-334; (1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 1432500-66-7. Molecular formula: C26H26N2O5. Mole weight: 446.5.
ML352
ML352 is a potent and non-competitive inhibitor of the presynaptic choline transporter (CHT; Ki value 92 nM). Alternative Names: ML352; ML-352; ML 352; VU0476201; VU-0476201; VU 0476201; VU0476328; VU-0476328; VU 0476328; N-((3-Isopropylisoxazol-5-yl)methyl)-4-methoxy-3-((1-methylpiperidin-4-yl)oxy)benzamide; 4-methoxy-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide. Grades: 98%. CAS No. 1649450-12-3. Molecular formula: C21H29N3O4. Mole weight: 387.47.
MLi-2
MLi-2 is a potent, orally available and brain penetrant inhibitor of LRRK2 (IC50 = 0.76 nM) with excellent selectivity that shows >295-fold selectivity for over 300 kinases and a diverse panel of receptors and ion channels. Alternative Names: Merck lrrk2 inhibitor-2; MLi 2; MLi2; rel-3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole. Grades: 98%. CAS No. 1627091-47-7. Molecular formula: C21H25N5O2. Mole weight: 379.46.
MLN8054
MLN8054 is an aurora kinase inhibitor MLN8054, which is an orally bioavailable, highly selective small molecule inhibitor of the serine / threonine protein kinase Aurora A kinase with potential antineoplastic activity. Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregration, and inhibition of cell proliferation. Aurora A localizes in mitosis to the spindle poles and to spindle microtubules and is thought to regulate spindle assembly. Aberrant expression of Aurora kinases occurs in a wide variety of cancers, including colon and breast cancers. Alternative Names: MLN8054; MLN 8054; MLN-8054. CAS No. 869363-13-3. Molecular formula: C25H15ClF2N4O2. Mole weight: 476.86.
MLN-9708
ixazomib is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Compared to first generation PIs, second generation PIs may have an improved pharmacokinetic profile with increased potency and less toxicity. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquinated. Alternative Names: Ixazomib; MLN-9708; MLN 9708; MLN9708. CAS No. 1201902-80-8. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12.
MLS 1547
MLS 1547 is a dopamine D2 receptor agonist. It may be used in the combination with antipsychotic drugs. Alternative Names: MLS 1547; MLS1547; MLS-1547; 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol. Grades: ≥98% by HPLC. CAS No. 315698-36-3. Molecular formula: C19H19ClN4O. Mole weight: 354.83.
ML-SA1
ML SA1 is an activator of TRPML channels. It can induce TRPML-mediated Ca2+ release from lysosomes and reduce cholesterol accumulation in Niemann-Pick type C macrophages. Alternative Names: ML SA1; ML-SA1; 2-[2-oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione; 2-(2-oxo-2-(2,2,4-Trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl)isoindoline-1,3-dione; 2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydro-2H-quinolin-1-yl)-ethyl]-isoindole-1,3-dione; 2-[2-keto-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindoline-1,3-quinone;2-[2-oxidanylidene-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindole-1,3-dione; 1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-1,2,3,4-tetrahydro-2,2,4-trimethyl-quinoline;2-[2-oxo-2-(2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-2,3-dihydro-1H-isoindole-1,3-dione; 2-{2-oxo-2-[2,2,4-trimethyl-3,4-dihydro-1(2H)-quinolinyl]ethyl}-1H-isoindole-1,3(2H)-dione;quinoline, 1-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-1,2,3,4-tetrahydro-2,2,4-trimethyl-. Grades: 95%. CAS No. 332382-54-4. Molecular formula: C22H22N2O3. Mole weight: 362.43.
ML-SI3
ML-SI3 is an antagonist of the TRPML family of calcium channels. ML-SI3 can prevent lysosomal calcium efflux and has been reported to block downstream TRPML1-mediated induction of autophagy. Alternative Names: N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]benzenesulfonamide. Grades: 98%. CAS No. 891016-02-7. Molecular formula: C23H31N3O3S. Mole weight: 429.58.
MMP-13 Inhibitor
MMP-13 Inhibitor is a potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 value of 8 nM. Alternative Names: Collagenase-3 Inhibitor; Matrix Metalloproteinase-13 Inhibitor; 4,6-Pyrimidinedicarboxamide; N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide. Grades: ≥98%. CAS No. 544678-85-5. Molecular formula: C22H20F2N4O2. Mole weight: 410.4.
MMP-2 Inhibitor I
MMP-2 Inhibitor I is a reversible inhibitor of matrix metalloproteinase 2 (MMP-2) with Ki value of 1.6 μM. It attenuates cancer cell migration via inhibition of MMP-2. Alternative Names: Matrix Metalloproteinase-2 Inhibitor I; cis-9-Octadecenoyl-N-hydroxylamide; Oleylhydroxamate; N-Hydroxyoleamide; OA-Hy; Oleoyl-N-hydroxylamide. Grades: ≥98%. CAS No. 10335-69-0. Molecular formula: C18H35NO2. Mole weight: 297.5.
MMP-2/MMP-9 Inhibitor I
MMP-2/MMP-9 inhibitor I is a potent inhibitor of matrix metalloproteinase MMP-2/MMP-9 with IC50 values of 310 and 240 nM, respectively. It blocks MMP-2/MMP-9-dependent invasion, tumor growth, and metastasis in both cell culture and mouse tumor models. Alternative Names: Gelatinase A; N-([1,1'-biphenyl]-4-ylsulfonyl)-D-phenylalanine. Grades: 98%. CAS No. 193807-58-8. Molecular formula: C21H19NO4S. Mole weight: 381.44.
MMV030084
MMV030084 is a potent PKG inhibitor that inhibits hepatocyte invasion by Plasmodium sporozoites, merozoite egress from asexual blood stage schizonts, and male gamete exflagellation. Alternative Names: MMV 030084; MMV-030084. Grades: >98%. CAS No. 342434-07-5. Molecular formula: C18H19ClN4O. Mole weight: 342.83.
Moclobemide
Moclobemide is a reversible monoamine oxidase A (MAO-A) inhibitor, displaying antidepressive activity. Alternative Names: Ro11-1163; Ro 11-1163; Ro111163; Ro-111163; Ro 111163; Moclobemide; brand name: Amira; Aurorix; Clobemix; Depnil; Manerix; 4-chloro-N-(2-morpholin-4-ylethyl)benzamide. Grades: 98%. CAS No. 71320-77-9. Molecular formula: C13H17ClN2O2. Mole weight: 268.74.
Mogroside III
Mogroside III is extracted from the fruits of Siraitia grosvenorii Swingle. Alternative Names: (3β,9β,10α,11α,24R)-3-(β-D-Glucopyranosyloxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside. Grades: >98%. CAS No. 130567-83-8. Molecular formula: C48H82O19. Mole weight: 963.15.
Mogroside IV
Mogroside IV is extracted from the fruit of Siraitia grosvenorii Swingle. It exhibited maltase inhibitory effect. Alternative Names: (1S,4R,9β,11α,24R)-1-{[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy}-11,25-dihydroxy-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-en-24-yl 2-O-β-L-glucopyranosyl-β-D-glucopyranoside; β-D-Glucopyranoside, (1R,4R)-4-[(3β,9β,10α,11α,17β)-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-11-hydroxy-4,4,9,14-tetramethylestr-5-en-17-yl]-1-(1-hydroxy-1-methylethyl)pentyl 2-O-β-L-glucopyranosyl-. Grades: >98%. CAS No. 89590-95-4. Molecular formula: C54H92O24. Mole weight: 1125.29.
Mogroside VI
Mogroside VI is extracted from the fruits of Siraitia grosvenorii Swingle. Alternative Names: Neomogroside; (1S,4R,9β,11α,24R)-1-{[β-D-Glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->6)]-β-D-glucopyranosyl]oxy}-11,25-dihydroxy-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-en-24-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->6)]-β-D-glucopyranoside; β-D-Glucopyranoside, (3β,9β,10α,11α,17β)-17-[(1R,4R)-4-[[O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->6)]-β-D-glucopyranosyl]oxy]-5-hydroxy-1,5-dimethylhexyl]-11-hydroxy-4,4,9,14-tetramethylestr-5-en-3-yl O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->6)]-; β-D-Glucopyranoside, (3β,9β,10α,11α,24R)-11,25-dihydroxy-9-methyl-19-norlanost-5-ene-3,24-diyl bis[O-β-D-Glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->6)]-. Grades: >98%. CAS No. 89590-98-7. Molecular formula: C66H112O34. Mole weight: 1449.58.
Molecular sieve 4A
Molecular sieve 4A. Alternative Names: Molecular sieve 4A; Molecular sieves, 4A, high intensity. Grades: 95%. CAS No. 70955-01-0. Molecular formula: Na2O-Al2O3-2SiO2-nH2O. Mole weight: 60.08.
Molecular Sieves, Grade 513
Sodium aluminosilicate refers to compounds which contain sodium, aluminium, silicon and oxygen, and which may also contain water. These include synthetic amorphous sodium aluminosilicate, a few naturally occurring minerals and synthetic zeolites. Synthetic amorphous sodium aluminosilicate is widely used as a food additive, E-554, it is not strictly a chemical compound. Alternative Names: SODIUM ALUMINOSILICATE. CAS No. 1344-00-9. Molecular formula: AlNaO6Si2. Mole weight: 202.14.
Molybdenum Glycinate
Molybdenum Glycinate, a well-absorbed chelate, is a highly absorbable form of molybdenum. It is a cofactor in an important enzymatic reaction that is used for health supplements, regulation of copper levels, and detoxification. Molybdenum assists the liver to break down the toxin acetaldehyde produced by Candida and other fungi.
Mometasone Furoate
Mometasone furoate, prodrug of the free form mometasone, is an agent with high affinity for the glucocorticoid receptor with anti-allergic property. It can be used to treat asthma and allergic rhinitis. Uses: The treatment of asthma and allergic rhinitis. Alternative Names: Elocon; Nasonex; Sch32088; Twisthaler; Elomet; Asmanex; Mometasone 17-furoate. Grades: 98%. CAS No. 83919-23-7. Molecular formula: C27H30Cl2O6. Mole weight: 521.43.
Mometasone Furoate EP Impurity B
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: (11β,16α,17α)-9-Chloro-17-(2,2-dioxido-5H-1,2-oxathiol-4-yl)-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-androsta-1,4-dien-3-one; 9-Chloro-17β-(2,2-dioxo-2,5-dihydro-1,2λ6-oxathiol-4-yl)-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yl furan-2-carboxylate. Grades: > 95%. CAS No. 223776-49-6. Molecular formula: C28H31ClO8S. Mole weight: 563.07.
Mometasone Furoate EP Impurity C
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: (16α)-21-Chloro-17-[(2-furanylcarbonyl)oxy]-16-methyl-pregna-1,4-diene-3,11,20-trione; 9-Dechloro-11-Oxo Mometasone Furoate; 21-Chloro-16α-methyl-3,11,20-trioxopregna-1,4-dien-17-yl furan-2-carboxylate. Grades: > 95%. CAS No. 1305334-31-9. Molecular formula: C27H29ClO6. Mole weight: 484.98.
Mometasone Furoate EP Impurity D
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: 21-Chloro-17α-[(2-furanylcarbonxyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione; 9,11-Epoxidemometasone furoate; Mometasone Furoate Epoxy Impurity. Grades: > 95%. CAS No. 83881-09-8. Molecular formula: C27H29ClO6. Mole weight: 484.98.
Mometasone Furoate EP Impurity E
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: 11,17-Difuroate Mometasone Furoate; (11β,16α)-9,21-Dichloro-11,17-bis[(2-furanylcarbonyl)oxy]-16-methyl-pregna-1,4-diene-3,20-dione; 9,21-Dichloro-16α-methyl-3,20-dioxopregna-1,4-diene-11β,17-diyl di(furan-2-carboxylate). Grades: > 95%. CAS No. 1370190-33-2. Molecular formula: C32H32Cl2O8. Mole weight: 615.51.
Mometasone Furoate EP Impurity H
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: 21-Dechloro-21-Hydroxy Mometasone Furoate; 21-Hydroxy Deschloromometasone Furoate; (11β,16α)-9-Chloro-17-[(2-furanylcarbonyl)oxy]-11,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 9-Chloro-11β,21-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-17-yl furan-2-carboxylate. Grades: 95%. CAS No. 148596-90-1. Molecular formula: C27H31ClO7. Mole weight: 503.00.
Mometasone Furoate EP Impurity J
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: 6α-Methyl Mometasone Furoate. Molecular formula: C28H32Cl2O6. Mole weight: 535.46.
Mometasone Furoate EP Impurity K
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: Icometasone; Icomethasone; (11β,16α)-9-Chloro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 9-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. Grades: 98%. CAS No. 4647-20-5. Molecular formula: C22H29ClO5. Mole weight: 408.92.
Mometasone Furoate EP Impurity Q
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Alternative Names: 17α-Hydroxy-21-chloro-9β,11β-epoxy-16α-methylpregna-1,4-diene-3,20-dione; (9β,11β,16α)-21-Chloro-9,11-epoxy-17-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Mometasone Furoate Impurity Q. Grades: > 95%. CAS No. 83881-08-7. Molecular formula: C22H27ClO4. Mole weight: 390.91.
Monalizumab
Monalizumab is a first-in-class immune checkpoint inhibitor that targets Natural Killer Group 2A (NKG2A). Monalizumab increased degranulation and IFN-γ production by NKG2A+ NK cell against HLA-E+ target cells, thereby promoting NK cell effector functions. Alternative Names: IPH2201. CAS No. 1228763-95-8.
Monepantel, also known as AAD 1566, is a new anthelmintic agent used in the treatment of parasitic nematodes via stun or kill without damaging the host entity. Alternative Names: AAD1566; AAD 1566; N-(2-Cyano-1-((2S)-5-cyano-2-(trifluoromethyl)phenoxy)propan-2-yl)-4-(trifluoromethylsulfanyl)benzamide. Grades: 98%. CAS No. 887148-69-8. Molecular formula: C20H13F6N3O2S. Mole weight: 473.39.
Mono(6-(1,6-hexamethylenediamine)-6-deoxy)-beta-cyclodextrin is a derivative of β-cyclodextrin, which can help improve the solubility of the drug in oral preparations or preparations. Alternative Names: Mono(6-(1,6-hexamethylenediamine)-6-deoxy)-b-cyclodextrin; Mono(6-(1,6-hexamethylenediamine)-6-deoxy)-β-cyclodextrin; 6A-[(6-Aminohexyl)amino]-6A-deoxy-β-cyclodextrin. CAS No. 131991-61-2. Molecular formula: C48H84N2O34. Mole weight: 1233.17.
Mono(6-mercapto-6-deoxy)-beta-cyclodextrin
Mono(6-mercapto-6-deoxy)-beta-cyclodextrin, a remarkable biomedicine, plays a pivotal role in addressing an array of ailments. Unveiling unparalleled drug delivery traits, it fuels the enhancement of drug solubility and stability. Embraced widely in the pharmaceutical realm, it powerfully ameliorates drug bioavailability while selectively targeting diverse maladies like cancer, infections, and inflammatory disorders. Alternative Names: Mono(6-mercapto-6-deoxy)-β-cyclodextrin; 6A-Thio-β-cyclodextrin; 6-Deoxy-6-mercapto-β-cyclodextrin; 6-Deoxy-6-thiol-β-cyclodextrin; 6-Monodeoxy-6-monothio-β-cyclodextrin; Mono-6-deoxy-6-mercapto-β-cyclodextrin; Mono-6-mercapto-β-cyclodextrin. Grades: 98% by HNMR. CAS No. 81644-55-5. Molecular formula: C42H70O34S. Mole weight: 1151.05.
Monoacetyl bisacodyl
An impurity of Bisacodyl, which is a stimulant laxative belonging to the diphenylmethane family. It works by enhancing colonic motility and increasing stool water content. It needs to be converted into the active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM) in the gut to achieve its laxative effect. Alternative Names: 4-[(4-Hydroxyphenyl)(pyridin-2-yl)methyl]phenyl acetate; 4-[[4-(Acetyloxy)phenyl]-2-pyridinylmethyl]phenol; USP Bisacodyl Related Compound C; Bisacodyl USP Related Compound C; Bisacodyl Related Compound C; Bisacodyl Impurity C (Mixture of Diastereomers); (+/-)-Monoacetyl bisacodyl; Bisacodyl USP RC C; Bisacodyl EP Impurity C; Bisacodyl Impurity C; 4-[(RS)-(4-Hydroxyphenyl)(pyridin-2-yl)methyl]phenyl acetate. Grades: >95%. CAS No. 72901-16-7. Molecular formula: C20H17NO3. Mole weight: 319.36.
Monobromobimane is a cell-permeable and thiol-reactive fluorogenic probe. Monobromobimane readily reacts with protein thiols and generates stable fluorescence. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. Alternative Names: MBBr; 3-(bromomethyl)-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione. Grades: ≥98%. CAS No. 71418-44-5. Molecular formula: C10H11BrN2O2. Mole weight: 271.1.
Monocaprylin
The 100% natural Gyceryl Caprylate is an interesting processing aid in emulsification processes. It can accelerate the emulsification process and save time in production. Furthermore, Glyceryl Caprylate is the best known and most widely used natural preservative enhancer. It is the preferred enhancer in skin care formulations. It is particularly powerful in all types of emulsions. It improves the performance of any preservative system at just 0.3%. Perfect for all certified natural products. For use in water-based products, Glyceryl Caprylate requires a solubiliser. An addition of ethanol or pentylene glycol can reduce the use concentration of the solubiliser. Uses: Deodorant; decorative cosmetics; body care; face care. Alternative Names: Glyceryl caprylate; monooctanoin; Octanoic acid, monoester with 1,2,3-propanetriol; Octanoin. CAS No. 26402-26-6. Molecular formula: C11H22O4. Mole weight: 218.29.
Monodecarboxy piperacilloic acid
An impurity of Piperacillin, which is a broad-spectrum antibiotic used to treat serious, hospital-acquired infections in combination with the beta lactamase inhibitor tazobactam. Alternative Names: 4-Thiazolidinecarboxylic acid, 2-[[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]methyl]-5,5-dimethyl-, [2R-[2α(R*),4β]]-; α-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)benzylpenilloic acid; (2R,4S)-2-(((R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylic acid; Penilloic acids of piperacillin; Piperacillin EP Impurity C (2R-isomer). Grades: >95%. CAS No. 64817-23-8. Molecular formula: C22H29N5O6S. Mole weight: 491.57.
Monofucosyllacto-N-hexaose III, an imperative biomedicine, serves as a remarkable therapeutic solution within the biomedical domain. By selectively targeting distinct pharmaceuticals, this exquisite composition plays a vital role in combating an array of ailments comprising cancer, inflammation, and microbial infections. Alternative Names: MFLNH III; Fucosyllacto-N-hexaose III; alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-beta-D-GlcpNAc-(1->6)-[beta-D-Galp-(1->3)-beta-D-GlcpNAc-(1->3)]-beta-D-Galp-(1->4)-D-Glcp; Gal(b1-3)GlcNAc(b1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Gal(b1-4)aldehydo-Glc; O-β-D-Galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→3)-O-[β-D-galactopyranosyl-(1→4)]-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)]-O-β-D-galactopyranosyl-(1→4)-D-glucose; FLNH-II; FSLTNH3; Fucosyl-lacto-N-hexaose II; Fucosyllacto-N-hexaose; Fucosyllacto-N-hexaose II; Monofucosyllacto-N-hexaose. Grades: ≥90%. CAS No. 96656-34-7. Molecular formula: C46H78N2O35. Mole weight: 1219.12.
Monogalactosyldiacylglycerol
Monogalactosyldiacylglycerol is a vital component in the biomedical industry used extensively in the formulation of pharmaceuticals. It exhibits anti-inflammatory properties, making it an ideal candidate for developing drugs targeting inflammatory conditions like arthritand asthma. Alternative Names: 1,2-Diacyl-3-O-b-D-galactosyl-sn-glycerol; MGDG. Molecular formula: C45H74O10. Mole weight: 775.06.
Monoglycerides,palm-oil monoglycerides and diglycerides, hydrogenated
Monoglycerides,palm-oil monoglycerides and diglycerides, hydrogenated. CAS No. 67784-87-6.
Mono-Hydroxy Sugammadex
Mono-Hydroxy Sugammadex is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Alternative Names: Sugammadex-R1; Sugammadex Monohydroxy Impurity; Org48302. CAS No. 2376607-99-5. Molecular formula: C69H101O47S7.7Na. Mole weight: 2067.87.
Monolaurin
Monolaurin is a mono-ester with antibacterial and antiviral properties. Alternative Names: 1-Monolaurin; Lauricidin; Glyceryl monolaurate; Glycerol 1-laurate; 2,3-Dihydroxypropyl laurate; Dodecanoic acid, 2,3-dihydroxypropyl ester; Lauric acid 1-monoglyceride; 1-Lauroyl-rac-glycerol. Grades: Content: 90%. CAS No. 142-18-7. Molecular formula: C15H30O4. Mole weight: 274.45.
Monomer acid
Monomer acid. CAS No. 68955-98-6.
mono-Methyl hydrogen succinate
mono-Methyl hydrogen succinate (CAS# 3878-55-5) is one of the substances used in the study of lactobacillus plantarum culture supernatants with potential pro-heating and anti-pathogenic properties in skin chronic wounds. Alternative Names: 4-methoxy-4-oxobutanoic acid. Grades: 95 %. CAS No. 3878-55-5. Molecular formula: C5H8O4. Mole weight: 132.11.
Monomethyl Sphingosine (d18:1)
Monomethyl Sphingosine (d18:1), a sphingosine analog renowned for its potent inhibition of protein kinase C activity, serves as a pivotal tool in unraveling the intricate mechanisms underlying signal transduction pathways and cell cycle regulation. Its promising therapeutic implications extend to the realms of cancer treatment and neurodegenerative disorders, heralding a new era of scientific exploration. Alternative Names: sphingosine 2S, 3R, N-methylamine; N-methyl-D-erythro-sphinosine. Grades: >99%. CAS No. 2700-62-1. Molecular formula: C19H39NO2. Mole weight: 313.52.
Monomyristin
Monomyristin is used in colloidal chemistry as a nonionic surfactant in the development of micelles. It exhibits antibacterial activity against certain Gram-positive bacteria. Alternative Names: 2,3-Dihydroxypropyl tetradecanoate; 1-Myristoyl-rac-glycerol; Glyceryl monomyristate. Grades: >97.0%(GC). CAS No. 589-68-4. Molecular formula: C17H34O4. Mole weight: 302.455.
MONO-N-HEPTYLTIN TRICHLORIDE
MONO-N-HEPTYLTIN TRICHLORIDE. Uses: An organotin compound of type mensncl3-n(ch2)mme (n = 0-3, m = 0-7). Alternative Names: MONO-N-HEPTYLTIN TRICHLORIDE; Trichloroheptyl Stannane. CAS No. 59344-47-7. Molecular formula: C7H15Cl3Sn. Mole weight: 324.263.
Monophosphoryl Lipid A is a toll-like receptor 4 agonist with potential immunostimulatory activity, which is commonly used as a vaccine adjuvant. Alternative Names: MPLA (PHAD®); phosphorylated hexaacyl disaccharide; Glycopyranoside Lipid A. Grades: > 99%. CAS No. 1246298-63-4. Molecular formula: C96H184N3O22P. Mole weight: 1763.47.
Monopotassium L-glutamate
Monopotassium glutamate can be used as a flavor enhancer in food. Alternative Names: L-Glutamic acid, potassium salt (1:1); L-Glutamic acid, monopotassium salt; Glutamic acid, monopotassium salt, L-; Kaglutam; Monopotassium glutamate; MPG; Potassium glutamate; L-Glutamic acid potassium salt; Potassium (S)-2-amino-4-carboxybutanoate. CAS No. 19473-49-5. Molecular formula: C5H8KNO4. Mole weight: 185.24.