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Z-LEU-SER-OME
Z-LEU-SER-OME. Alternative Names: Z-LEU-SER-OME. CAS No. 40290-56-0. Molecular formula: C18H26N2O6. Mole weight: 366.41.
ZLN005
Selective transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). ZLN005 selectively stimulated the expression of PGC-1α and downstream genes in skeletal muscle cells, and led to changes in glucose uptake, and fatty acid oxidation in L6 myotubes in a AMPK dependent manner. Since ZLN 005 did not increase the expression of the PGC-1α gene in rat primary hepatocytes, it is hypothesized that expression of PGC-1α was regulated in a cell type-specific manner. ZLN005 exerts promising therapeutic effects for treating type 2 diabetes, as PGC-1α is a powerful transcriptional coregulator of GLUT4 and mitochondrial genes, a crucial player in the field of glucose uptake in skeletal muscle. Alternative Names: ZLN005; ZLN-005; ZLN 005. Grades: >98%. CAS No. 49671-76-3. Molecular formula: C17H18N2. Mole weight: 250.34.
Zn(II) Mesoporphyrin IX
Zn(II) Mesoporphyrin IX. CAS No. 14354-67-7. Molecular formula: C34H36N4O4Zn. Mole weight: 630.06.
Zoledronic acid (zoledronate) is a bisphosphonate bone resorption inhibitor, an inhibitor of farnesyl diphosphate (FPP) synthase which results in downstream inhibition of osteoclast activity and reduced bone resorption and turnover. It has been used to treat postmenopausal osteoporosis, Paget's disease, hypercalcemia, and along with cancer chemotherapy to treat bone damage caused by cancer that has spread to the bones. Alternative Names: Zoledronate monohydrate; CGP 42446 monohydrate; ZOL 446 monohydrate; CGP42446 monohydrate; ZOL446 monohydrate; CGP-42446 monohydrate; ZOL-446 monohydrate; CGP42446A monohydrate. Grades: >98%. CAS No. 165800-06-6. Molecular formula: C5H12N2O8P2. Mole weight: 290.1.
Zoliflodacin
Zoliflodacin, an oxazolidinone derivative, has been found to be a DNA gyrase inhibitor that could be used as an antibacterial agent. It is still under Phase II trial in Gonorrhea. Uses: Topoisomerase ii inhibitors. Alternative Names: UNII-FWL2263R77; AZD-0914; AZD0914; AZD 0914; FWL2263R77; FWL 2263R77; FWL-2263R77; Zoliflodacin; AZD0914; CHEMBL3544978; (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-((S)-4-methyl-2-oxooxazolidin-3-yl)-1,2,4,4a-tetrahydro-2'H,6H-spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1. Grades: 98%. CAS No. 1620458-09-4. Molecular formula: C22H22FN5O7. Mole weight: 487.40.
Zolmitriptan Impurity 1
One of the impurities of Zolmitriptan, which is a 5HTID-receptor agonist and has been found to be effective in the treatment of migraine. Alternative Names: (S)-4-(4-Hydrazinylbenzyl)-2-oxazolidinone; (4S)-4-[(4-hydrazinylphenyl)methyl]-2-Oxazolidinone. CAS No. 187975-62-8. Molecular formula: C10H13N3O2. Mole weight: 207.23.
Zolmitriptan N-Oxide
One of the impurities of Zolmitriptan, which is a 5HTID-receptor agonist and has been found to be effective in the treatment of migraine. Alternative Names: (4S)-4-[[3-[2-(Dimethyloxidoamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone, (S)-N,N-Dimethyl-2-{5-[(2-oxooxazolidin-4-yl)methyl]-1H-indol-3-yl}ethanamine oxide; Zolmitriptan Related Compound E. CAS No. 251451-30-6. Molecular formula: C16H21N3O3. Mole weight: 303.36.
Zolmitriptan Related Compound F
One of the impurities of Zolmitriptan, which is a 5HTID-receptor agonist and has been found to be effective in the treatment of migraine. Alternative Names: (N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer; (4S,4'S)-4,4'-[[4-(Dimethylamino)butylidene]bis[[3-[2-(dimethylamino)ethyl]-1H-indole-2,5-diyl]methylene]]bis[2-oxazolidinone]. CAS No. 1350928-05-0. Molecular formula: C38H53N7O4. Mole weight: 671.89.
Zolmitriptan R-isomer
One of the impurities of Zolmitriptan, which is a 5HTID-receptor agonist and has been found to be effective in the treatment of migraine. Alternative Names: (R)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; (4R)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone. CAS No. 139264-24-7. Molecular formula: C16H21N3O2. Mole weight: 287.36.
ZonylFS-300 fluorosurfactant
ZonylFS-300 fluorosurfactant. CAS No. 197664-69-0.
Zorevunersen
Zorevunersen (STK-001) is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome. Alternative Names: STK-001; STK 001; STK001. CAS No. 2415330-04-8. Molecular formula: C204H263N63O114P20S20. Mole weight: 6682.39.
Zosuquidar
Zosuquidar, also called as LY335979, a cyclopropyldibenzosuberane, was developed as an inhibitor of P-glycoprotein (P-gp). It is undergoing testing in a phase I/II trial clinical study in acute myeloid leukaemia. Alternative Names: (2R)-anti-5-(3-(4-(10,11-difluoromethanodibenzo-suber-5-yl)piperazin-1-yl)2-hydroxypropoxy)quinoline trihydrochlorideLY 335979; LY-335979LY335979RS 33295-198RS-33295-198zosuquidar trihydrochloride. CAS No. 167354-41-8. Molecular formula: C32H31F2N3O2. Mole weight: 527.60.
Zosuquidar trihydrochloride
Zosuquidar (LY335979) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with a Ki value of 60 nM. Alternative Names: LY 335979; LY-335979; D06387; RS-33295-198; Zosuquidar HCl. CAS No. 167465-36-3. Molecular formula: C32H34Cl3F2N3O2. Mole weight: 636.99.
zoxamide
zoxamide. Alternative Names: ZOXAMIDE; rh-7281; zoxamide (bsi,iso); Zoxamid. Grades: 95%. CAS No. 156052-68-5. Molecular formula: C14H16Cl3NO2. Mole weight: 336.644.
Z-PRO-LEU-OH
Z-PRO-LEU-OH. Alternative Names: N-CARBOBENZOXY-L-PROPYL-L-LEUCINE; Z-PRO-LEU-OH; Z-L-PROLYL-L-LEUCINE. Grades: 95%. CAS No. 1634-90-8. Molecular formula: C19H26N2O5. Mole weight: 362.42.
(Z)-Tritriacont-24-en-16-one
(Z)-Tritriacont-24-en-16-one is a useful research chemical, a long-chain unsaturated ketone. Alternative Names: (Z)-24-tritriaconten-16-one; (Z)-tritriacont-24-en-16-one; 24-Tritriaconten-16-one, (Z)-. CAS No. 71177-09-8. Molecular formula: C33H64O. Mole weight: 476.86.
ZXH 3-26
ZXH 3-26 is a potent and selective BRD4 degrader (DC50 ~ 5 nM). Alternative Names: methyl 2-((6S)-4-(4-chlorophenyl)-2-((5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)pentyl)carbamoyl)-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate; Methyl {(6S)-4-(4-chlorophenyl)-2-[(5-{[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}pentyl)carbamoyl]-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl}acetate; 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2-[[[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]pentyl]amino]carbonyl]-3,9-dimethyl-, methyl ester, (6S)-; Methyl (6S)-4-(4-chlorophenyl)-2-[[[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]pentyl]amino]carbonyl]-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate; ZXH 3-26. Grades: ≥98% by HPLC. CAS No. 2243076-67-5. Molecular formula: C38H37ClN8O7S. Mole weight: 785.27.
ZY-19489
ZY-19489 is a novel anti-malarial drug that belongs to the triaminopyrimidine group. It inhibits parasitemia-induced infection. Alternative Names: Sutidiazine. Grades: >98.0%. CAS No. 1821293-40-6. Molecular formula: C24H32FN9. Mole weight: 465.57.