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5-Hydroxyindolmycin
5-Hydroxyindolmycin is an antibiotic produced by the fermentation of Serptomyces griseus in the presence of 5-hydroxytryptophan or 5-hydroxyindole. It has weak anti-Gram-positive and negative bacteria activity. Molecular formula: C14H15N3O3. Mole weight: 273.29.
5-Hydroxylecanoric acid
5-Hydroxylecanoric acid is a derivative of Lecanoric acid, which is a didepside produced by several species of lichen. Molecular formula: C16H14O8. Mole weight: 334.28.
5-Hydroxymethylblasticidin S is a broad-spectrum antibiotic produced by Streptomyces setonii. Synonyms: 1- (4-{[3-Amino-1-hydroxy-5- (N-methylcarbamimidamido) pentylidene]amino}-2, 3, 4-trideoxyhex-2-enopyranuronosyl) -5- (hydroxymethyl) -4-imino-1, 4-dihydropyrimidin-2-ol. CAS No. 123067-52-7. Molecular formula: C18H28N8O6. Mole weight: 452.46.
5-Hydroxymethyltubercidin
5-Hydroxymethyltubercidin is a semi-synthetic antibiotic made from tuberculin-5-carboxylic acid. Synonyms: 5-(hydroxymethyl)-7-pentofuranosyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine. CAS No. 49558-38-5. Molecular formula: C12H16N4O5. Mole weight: 296.28.
5-Methoxyindolmycin is an antibiotic produced by the fermentation of Serptomyces griseus in the presence of 5-methoxytryptophan or 5-methoxyindole. It has weak anti-Gram-positive and negative bacteria activity. Molecular formula: C15H17N3O3. Mole weight: 287.31.
5-Methoxylecanoric acid
It is a new depside from Melanelia glabratula. Molecular formula: C17H16O8. Mole weight: 348.30.
5-Methoxy-P-Toluquinone
5-Methoxy-P-Toluquinone is a quinone antibiotic produced by Coprinus siniilis and Lentinus degener. It has antibacterial, mycobacterial and fungal effects, but has weaker effects on Gram-negative bacteria. Synonyms: Coprinin; 4-Methoxytoluquinone; 2-Methoxy-5-methyl-1,4-benzoquinone. CAS No. 614-13-1. Molecular formula: C8H8O3. Mole weight: 152.15.
5-N-Acetylardeemin
5-N-Acetylardeemin is a heterocyclic compound isolated from Aspergillus fischeri var.brasiliensis AB 1826 M-35. 5-N-Acetylardeemin can enhance the cytotoxicity of the antineoplastic drug vincristine to multi-drug resistant human tumor cells. Synonyms: 5-N-Acetylardeemin; N-Acetylardeemin. CAS No. 148441-26-3. Molecular formula: C28H28N4O3. Mole weight: 468.55.
5-O-Acetyl-4-O-methylhiascic acid
It is a new tridepside from the lichen Koerberiella wimmeriana. Synonyms: 3-Acetoxy-6-hydroxy-4-methoxy-2-methyl-benzoic acid 4-(4-carboxy-3-hydroxy-5-methyl-phenoxycarbonyl)-3-hydroxy-5-methyl-phenyl ester. CAS No. 133177-73-8. Molecular formula: C27H24O12. Mole weight: 540.47.
5-O-Methylhiascic acid
It is isolated from an unnamed crustose lichen and detected in Parmelia horrescens, Parmelia pseudofatiscens and Parmelia dissecta. Synonyms: Benzoic acid, 4-[(4,6-dihydroxy-3-methoxy-2-methylbenzoyl)oxy]-2-hydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester; 4,6-Dihydroxy-3-methoxy-2-methyl-benzoic acid 4-(4-carboxy-3-hydroxy-5-methyl-phenoxycarbonyl)-3-hydroxy-5-methyl-phenyl ester. CAS No. 65614-38-2. Molecular formula: C25H22O11. Mole weight: 498.44.
6,11-Di-O-acetylalbrassitriol is produced from the fungus Penicillium sp. Synonyms: 1,4-Naphthalenediol, 1-[(acetyloxy)methyl]-1,4,4a,5,6,7,8,8a-octahydro-2,5,5,8a-tetramethyl-, 4-acetate, [1R-(1α, 4α, 4aα, 8aβ)]-. Grades: 98.0%. CAS No. 110538-20-0. Molecular formula: C19H30O5. Mole weight: 338.44.
6,8-Di-O-methylcitreoisocoumarin
6,8-Di-O-methylcitreoisocoumarin is produced from Trichoderma sp. HPQJ-34. Synonyms: 3-(2-Hydroxy-4-oxopentyl)-6,8-dimethoxy-1H-isochromen-1-one; 3-(4-Oxo-2-hydroxypentyl)-6,8-dimethoxy-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one, 3-(2-hydroxy-4-oxopentyl)-6,8-dimethoxy-. Grades: ≥98%. CAS No. 908098-80-6. Molecular formula: C16H18O6. Mole weight: 306.31.
6-Acetylbisdethiobis (methylthio)gliotoxin
It is a natural product first produced by the strain of the fungus D. cejpii. It shows anti-inflammatory properties and inhibits TNF-α-induced NF-κB activity. Synonyms: 6-acetylbis (dethio)bis (methylsulfanyl)gliotoxin; (3R,5aS,6S,10aR)-1,2,3,4,5a,6,10,10a-octahydro-3-(hydroxymethyl)-2-methyl-3,10a-bis(methylsulfanyl)-1,4-dioxopyrazino[1,2-a]indol-6-yl acetate; 6-acetylbis(methylthio)gliotoxin. CAS No. 146016-65-1. Molecular formula: C17H22N2O5S2. Mole weight: 398.50.
6-Chloro-2-methoxypyridine-3-boronic acid is an essential compound used in the biomedicine industry. It exhibits significant potential in the development of drugs for the treatment of various diseases. Through its unique chemical properties, it serves as a crucial building block for synthesizing pharmaceutical compounds targeting specific illnesses and disorders. The compound's versatility and efficacy make it a valuable tool in drug discovery and development processes. Synonyms: 6-chloro-2-methoxypyridin-3-ylboronic acid. Grades: 97+%. CAS No. 1072946-50-9. Molecular formula: C6H7BClNO3. Mole weight: 187.39.
6'''-Deamino-6'''-hydroxyneomycin B dihydrate is an aminoglycoside antibiotic produced by Streptomyces fradiae UC 75. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-Deamino-6'''-hydroxyneomycin B; D-Streptamine, O-2-amino-2-deoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-, (R-(E))-; D-Streptamine, O-2-amino-2-deoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-2-deoxy-, dihydrate. CAS No. 78524-73-9. Molecular formula: C23H45N5O14. Mole weight: 615.63.
6'''-Deamino-6'''-hydroxyneomycin C
6'''-Deamino-6'''-hydroxyneomycin C is an aminoglycoside antibiotic produced by Streptomyces fradiae UC 75. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-hydroxyneomycin C; Neomycin Y2; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside. Molecular formula: C23H45N5O14. Mole weight: 615.63.
6'''-Deamino-6'''-hydroxyparomomycin
6'''-Deamino-6'''-hydroxyparomomycin is an aminoglycoside antibiotic produced by Streptomyces rimosus forma paromomycinus A67M15. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-Hydroxyparmomomycin; 6'''-Deamino-6'''-hydroxyparomomycin I. CAS No. 78524-72-8. Molecular formula: C23H44N4O15. Mole weight: 616.61.
6'''-Deamino-6'''-hydroxyparomomycin II
6'''-Deamino-6'''-hydroxyparomomycin II is an aminoglycoside compound produced by Streptomyces rimosus forma paromomycinus A67M15. Synonyms: 5'''-Epi-6'''-deamino-6'''-hydroxyparomomycin. Molecular formula: C23H44N4O15. Mole weight: 616.61.
6-Deoxy-8-D-methylrabelomycin
6-Deoxy-8-D-methylrabelomycin is produced by the strain of Streptomyces tsusimaensis M131038F7. It has anti-gram-positive bacteria activity and weak activity of anti-mycobacterium, gram-negative positive bacteria and candida albicans. Molecular formula: C20H16O5. Mole weight: 336.34.
6-Deoxyilludin M
6-Deoxyilludin M is produced by the strain of Pleurutus japonicus. It has anti-mouse leukemia P388 activity. Synonyms: deoxyilludin M; (R)-2',3'-Dihydro-6'-hydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one. CAS No. 112953-12-5. Molecular formula: C15H20O2. Mole weight: 232.32.
6-Deoxyparomomycin
6-Deoxyparomomycin is produced by the strain of Streptomyces rimosus forma paromomycinus. The antibacterial activity was similar to that of paramycin. Molecular formula: C23H45N5O13. Mole weight: 599.63.
6-Ethoxyethyl-5-hydroxy-2,7-dime-thoxy-1,4-naphtoquinone is a naphthoquinone compound produced by Guignardia laricina GM-7. It can cause the larch branches to wither and inhibit the germination and growth of lettuce seeds. CAS No. 86343-22-8. Molecular formula: C16H18O6. Mole weight: 306.31.
6-Formyl-5,7-dihydroxyphthalide
4,5-Dichloro-3-O-methylnorlichexanthone is a barbatolic acid found in B. nadvornikiana and Alectoria nigricans. Molecular formula: C9H6O5. Mole weight: 194.14.
It is isolated from cultures in vitro of Sporotrichum laxum. Synonyms: 1(3H)-Isobenzofuranone, 4,5-dihydroxy-3-[(13R)-13-hydroxy-10-oxotetradecyl]-7-methoxy-, (3R)-; (R)-4,5-dihydroxy-3-((R)-13-hydroxy-10-oxotetradecyl)-7-methoxyisobenzofuran-1(3H)-one. CAS No. 919361-42-5. Molecular formula: C23H34O7. Mole weight: 422.51.
6-Hydroxytetrangulol
6-Hydroxytetrangulol is a CPP32 protease inducer produced by Streptomyces sp. Molecular formula: C19H12O5. Mole weight: 320.30.
It is the core salicylic acid unit in the biosynthesis of many secondary metabolites in actinomycetes, fungi and lichens. This polyketone is a key structural part of many different antibiotics and anticancer drugs, such as chlorothricin, maduropeptin, neocarzinostatin and terreic acid. Synonyms: 6-Hydroxy-o-toluic acid; 2,6-Cresotic acid; 6-MSA; 6-Methyl-2-hydroxybenzenecarboxylate; 6-hydroxy-2-methylbenzoic acid; NSC 403256. Grades: > 95 % by HPLC. CAS No. 567-61-3. Molecular formula: C8H8O3. Mole weight: 152.15.
6''-O-Carbamoyltobramycin
6''-O-Carbamoyltobramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. 6''-O-Carbamoyltobramycin has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria. Synonyms: Nebramycin V'; Nebramycin factor 5'; Nebramycin-5'; 6-O-Carbamoyltob; (1S,2S,3R,4S,6R)-4,6-diamino-3-[(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-6-O-carbamoyl-3-deoxy-alpha-D-glucopyranoside. Grades: >96%. CAS No. 51736-77-7. Molecular formula: C19H38N6O10. Mole weight: 510.54.
6-O-Methylnorlichexanthone
6-O-Methylnorlichexanthone is a xanthone compound. Synonyms: Methylnorlichexanthone; Xanthen-9-one, 1,3-dihydroxy-6-methoxy-8-methyl- (6CI,8CI); 1,3-Dihydroxy-6-methoxy-8-methyl-9H-xanthen-9-one. CAS No. 22938-77-8. Molecular formula: C15H12O5. Mole weight: 272.25.
6-O-Methylthiophanic acid
6-O-methylnorlichexanthone is a xanthone compound obtained from Lecanora contractula. Synonyms: Xanthen-9-one, 2,4,5,7-tetrachloro-1,3-dihydroxy-6-methoxy-8-methyl- (8CI). CAS No. 31913-68-5. Molecular formula: C15H8Cl4O5. Mole weight: 410.03.
It is a powerful β-lactam inhibitor originally isolated from Aspergollus candidus. Synonyms: FR 900318; FR-900318; (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(sulfoamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 3,3-Dimethyl-7-oxo-6-(sulfoamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. CAS No. 83670-99-9. Molecular formula: C8H12N2O6S2. Mole weight: 296.32.
7-Amino-Actinomycin-D, a semisynthetic derivate of actinomycin, has been found to be able to bind to single stranded DNA and could be used as a fluorescent dye in biological experiement. Synonyms: 7-Amino-Actinomycin-D; 7-Amino-AMD; 7-Aminoactinomycin D. Grades: ≥97%. CAS No. 7240-37-1. Molecular formula: C62H87N13O16. Mole weight: 1270.43.
7-Amino-9a-O-methyl-10-decarbamoyloxy-9-dehydro-7-demethoxymitomycin B
It is produced by the strain of Streptomyces caespitosus KY 2072. It has the activity of anti-gram-positive bacteria. Molecular formula: C15H17N3O3. Mole weight: 287.32.
7-Aminoheptanoic acid
7-Aminoheptanoic Acid is an aliphatic ω-amino acid that acts as a ligand for recombinant kringle 2 domain (residues 180-261) of human tissue-type plasminogen. Synonyms: 7-Ahp-OH; 7-Aminoenanthic acid; omega-Aminoenantic acid; 7-Amino-heptanoic acid; HEPTANOIC ACID, 7-AMINO-; 7-Aminohepentanoic acid; Aminoenanthic acid; Amino-enanthylic acid; omega-Aminoheptanoic acid. Grades: ≥ 99%. CAS No. 929-17-9. Molecular formula: C7H15NO2. Mole weight: 145.20.
It is produced by the strain of Cylindrocarpon PF-60. It has anti-gram positive bacteria and negative bacteria activity. Molecular formula: C29H34O10. Mole weight: 542.57.
7beta,8beta-Diepoxyroridin H
7beta,8beta-Diepoxyroridin H is an antibiotic produced by Cylindrocarpon PF-60. It has anti-gram-positive and negative bacteria activity. CAS No. 64687-84-9. Molecular formula: C29H34O10. Mole weight: 542.57.
7beta,8beta-Epoxyroridin E
7beta,8beta-Epoxyroridin E is an antibiotic produced by Cylindrocarpon PF-60. It has anti-gram-positive and negative bacteria activity. Molecular formula: C29H36O9. Mole weight: 528.59.
7beta,8beta-Epoxyroridin H
7beta,8beta-Epoxyroridin H is an antibiotic produced by Cylindrocarpon PF-60. It has anti-gram-positive and negative bacteria activity. CAS No. 64687-85-0. Molecular formula: C29H34O9. Mole weight: 526.57.
It is produced by the strain of Fusarium aquaedeductuum WC-5228. It inhibits the binding activity of type B endothelin-1 (ETB) receptor with IC50 of 50 μmol/L. It has antibacterial activities against Gram-positive bacteria, including vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus. Synonyms: 7-Chloro-6,8-dihydroxy-1-meth-oxy-3-methylanthraquinone; 1,3-dihydroxy-8-methoxy-2-chloro-6-methylanthraquinone. CAS No. 19267-89-1. Molecular formula: C16H11ClO5. Mole weight: 318.71.
7-Chloro-3-O-methylnorlichexanthone
7-Chloro-3-O-methylnorlichexanthone is a lichen xanthone. Molecular formula: C15H11ClO5. Mole weight: 306.70.
7-Chloro-6-O-methylnorlichexanthone
It is produced by the strain of Lecanora sp, L.salina and L.populicola. Synonyms: 9H-Xanthen-9-one, 2-chloro-6,8-dihydroxy-3-methoxy-1-methyl-; 2-Chloro-6,8-dihydroxy-3-methoxy-1-methyl-9H-xanthen-9-one. CAS No. 39818-07-0. Molecular formula: C15H11ClO5. Mole weight: 306.70.
It is produced by the strain of Lecanora sp and L.populicola. Synonyms: 2-Chloro-8-Hydroxy-3,6-Dimethoxy-1-Methyl-9H-Xanthen-9-One; 9H-Xanthen-9-one, 2-chloro-8-hydroxy-3,6-dimethoxy-1-methyl-. CAS No. 141861-71-4. Molecular formula: C16H13ClO5. Mole weight: 320.72.
7-Demethoxy-7-amino-9a-O-methylmitomycin is a mito-mycin antibiotic produced by Streptomyces caespitosus. It has anti-tumor and gram-positive bacteria activity. Synonyms: Mitomycin E. CAS No. 74707-94-1. Molecular formula: C16H20N4O5. Mole weight: 348.35.
7-Demethylnaphterpin
7-Demethylnaphterpin is a free radical scavenger produced by Streptomyces prunicololor. Synonyms: Naphthgeranine A. CAS No. 137109-43-4. Molecular formula: C20H20O5. Mole weight: 340.37.
7-Demethylpiericidin A1
7-Demethylpiericidin A1 is a pierceridin antibiotic produced by Streptomyces sp. SN-198. It has antifungal and gram-negative bacteria activity. Molecular formula: C24H35NO4. Mole weight: 401.54.
7-Deoxyloganin
It is produced by the strain of Strychnos nux-vomica. 7-Deoxyloganin is a precursor of Loganin. Synonyms: Deoxyloganin. CAS No. 26660-57-1. Molecular formula: C17H26O9. Mole weight: 374.38.
7-desacetoxyhelvolic acid
It is produced by the strain of Cephalosporium caerulens. It is a steroidal antibiotic. It has anti-gram-positive bacterial activity. Molecular formula: C31H42O6. Mole weight: 510.66.
7-Hydro-8-methylpteroylglutamyl-glutamic acid
7-Hydro-8-methylpteroylglutamyl-glutamic acid is an antifolate produced by actinomycete SK-2049. It only has the activity against Enterococcus faecium and has no effect on other bacteria and fungi. Thymidine and folate-related compounds can counteract its activity. Synonyms: 7-Hydro-8-methylpteroylglutamyl-glutamic acid; N-(N-(4-(((2-Amino-1,4,7,8-tetrahydro-8-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-gamma-glutamyl)-L-glutamic acid; L-Glutamic acid, N-(N-(4-(((2-amino-1,4,7,8-tetrahydro-8-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-gamma-glutamyl)-. CAS No. 108402-49-9. Molecular formula: C25H30N8O9. Mole weight: 586.55.
7-Hydroxycalamene
It is the constituent of Ulmus thomasii and isolated from Tilia europea infected with Ganoderma applanatum. Synonyms: 2-Naphthalenol, 5,6,7,8-tetrahydro-3,8-dimethyl-5-(1-methylethyl)-, (5S,8R)-. CAS No. 76465-67-3. Molecular formula: C15H22O. Mole weight: 218.33.
7-Hydroxyguanine
7-Hydroxyguanine is an antibiotic produced by Streptomyces purpurascens. It can inhibit the growth of L1210 leukemia cells. Synonyms: Guanine 7-oxide; Guanine 7-N-oxide. CAS No. 16870-91-0. Molecular formula: C5H5N5O2. Mole weight: 167.13.
7-Hydroxypestalotin
A minor analogue metabolite of pestalotin isolated from penicillium decumbens. It is phytotoxic against evening primrose, prickly sida, johnsongrass, morning glory, lambsquarter and A. abla. Synonyms: 6,7-Dihydroxy-3-methoxy-2-decen-5-olide; LL-P880 beta; (6S)-6-[(1S,2R)-1,2-Dihydroxypentyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one; (6S,1'S,2'R)-LL-P880β; LL-P880&beta. Grades: >99% by HPLC. CAS No. 41164-59-4. Molecular formula: C11H18O5. Mole weight: 230.26.