BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Dabigatran ethyl ester | Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory. Synonyms: Dabigatran ethyl ester; BIBR-951CL; BIBR 951CL; BIBR951CL; UNII-KJ4EH9410G. Grades: >98%. CAS No. 429658-95-7. Molecular formula: C27H29N7O3. Mole weight: 499.56. |  |
| Dabigatran ethyl ester hydrochloride | A derivative of Dabigatran, which acts as a non-peptide, direct thrombin inhibitor. Synonyms: Dabigatran Impurity O HCl; Dabigatran Ethyl Ester Hydrochloride Salt; Ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate hydrochloride. Grades: >95%. CAS No. 211914-50-0. Molecular formula: C27H30ClN7O3. Mole weight: 536.03. | |
| Dabigatran impurity 002 | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Molecular formula: C11H10N2O4. Mole weight: 234.21. | |
| Dabigatran impurity 004 | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Molecular formula: C16H18N4O4. Mole weight: 330.34. | |
| Dabigatran impurity 005 | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Molecular formula: C16H16N4O5. Mole weight: 344.32. | |
| Dabigatran impurity 006 | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Molecular formula: C17H18N4O5. Mole weight: 358.35. | |
| Dabigatran Impurity 20 | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: Dabigatran Impurity 007. Grades: 95%. CAS No. 1408238-39-0. Molecular formula: C33H39N7O5. Mole weight: 613.71. | |
| Dabigatran Impurity 50 | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: Dabigatran impurity 003. Molecular formula: C16H18N4O3. Mole weight: 314.33. | |
| Dabigatran Impurity E | O-(2-Heptyl) Dabigatran Ethyl Ester is an impurity of Dabigatran Ethyl Ester, a nonpeptide, direct thrombin inhibitor. Synonyms: O-(2-Heptyl) Dabigatran Ethyl Ester; Ethyl 3- (2- ( ( (4- (N- ( (Heptan-2-yloxy) carbonyl) carbamimidoyl) phenyl) amino) methyl) -1-methyl-N- (pyridin-2-yl) -1H-benzo[d]imidazole-5-carboxamido) propanoate. Grades: > 95%. CAS No. 1610758-21-8. Molecular formula: C35H43N7O5. Mole weight: 641.76. | |
| Dabigatran Impurity H | Des-(N-2-pyridyl-β-alanine ethyl ester) Dabigatran etexilate 5-ethyl carboxylate is a derivative of Dabigatran, an oral thrombin inhibitor used to prevent venous thromboembolism. Synonyms: Des-(N-2-pyridyl-β-alanine Ethyl Ester) Dabigatran Etexilate 5-Ethyl Carboxylate; 2- [ [ [4- [ [ [ (Hexyloxy) carbonyl] amino] iminomethyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 1408238-36-7. Molecular formula: C26H33N5O4. Mole weight: 479.57. | |
| Dabigatran Impurity K | An impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots. Grades: > 95%. CAS No. 211915-00-3. Molecular formula: C33H39N7O5. Mole weight: 613.72. | |
| DAF-2 | DAF-2 is a fluorescent indicator for the detection of nitric oxide (NO). Synonyms: DAF-2-CAS 205391-01-1-Calbiochem;4,5-Diaminofluorescein; 2-(3,6-dihydroxy-4,5-diamino-9H-xanthen-9-yl)-benzoic acid. Grades: ≥98%. CAS No. 205391-01-1. Molecular formula: C20H14N2O5. Mole weight: 362.3. | |
| Daglutril | Daglutril is a dual endothelin converting enzyme (ECE)/neutral endopeptidase (NEP) inhibitor used for the treatment of hypertension and heart failure andpulmonary. It reduces proteinuria and urinary albumin excretion in diabetic rats, and inhibits systemic conversion of big endothelin-1 in humans. Synonyms: SLV-306; SLV306; SLV 306; 2- [ (3S) -3- [ [1- [ (2R) -2-ethoxycarbonyl-4-phenylbutyl] cyclopentanecarbonyl] amino] -2-oxo-4, 5-dihydro-3H-1-benzazepin-1-yl] acetic acid. Grades: 99%. CAS No. 182821-27-8. Molecular formula: C31H38N2O6. Mole weight: 534.64. | |
| Daidzin 6''-O-malonate | Daidzin 6''-O-malonate is a biomedical product used in the treatment of alcohol dependency and cancer. It is derived from daidzein, a natural compound found in plants. Daidzin 6''-O-malonate targets specific receptors in the brain, reducing the craving for alcohol. Synonyms: Malonyldaidzin; Daidzin 6''-O-Malonate; 6''-O-Malonyldaidzin. CAS No. 124590-31-4. Molecular formula: C24H22O12. Mole weight: 502.42. | |
| [D-Ala2]-Leucine enkephalin | [D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors. Synonyms: Leuphasyl; NSC 374895; NSC-374895; NSC374895; DALLE; (D-Ala2)-Leu-Enkephalin; [D-Ala2]-Leu-Enkephalin. CAS No. 64963-01-5. Molecular formula: C29H39N5O7. Mole weight: 569.65. | |
| D-Ala-Lys-AMCA | D-Ala-Lys-AMCA is a proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. Grades: >98%. CAS No. 375822-19-8. Molecular formula: C21H28N4O6. Mole weight: 432.47. | |
| DALARGIN | Dalargin is an endogenous opioid peptide leucine-encephalin. Synonyms: (D-Ala2)-Leu-Enkephalin-Arg; H-Tyr-D-Ala-Gly-Phe-Leu-Arg-OH. Grades: 98%. CAS No. 81733-79-1. Molecular formula: C35H51N9O8. Mole weight: 725.83. | |
| Dalasetron Mesylate hydrate | Dalasetron Mesylate hydrate is a serotonin 5-HT3 receptor antagonist. It is used to treat nausea and vomiting following chemotherapy. Uses: Dalasetron mesylate hydrate is used to treat nausea and vomiting following chemotherapy. Synonyms: rel-(6R,9aS)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate hydrate. Grades: >98 %. CAS No. 878143-33-0. Molecular formula: C20H26N2O7S. Mole weight: 438.49. | |
| DAMGO | DAMGO is a highly selective peptide agonist of the μ opioid receptor. Uses: Analgesics, opioid. Synonyms: Y-d-Ala-G-Me-Phe-G-ol; L-tyrosyl-D-alanyl-glycyl-N-methyl-L-phenylalanyl-glycinol; DAGO; glyol; Dagol; 2-Ala-4-mephe-5-gly-enkephalin; (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin. Grades: ≥95%. CAS No. 78123-71-4. Molecular formula: C26H35N5O6. Mole weight: 513.59. | |
| Daminozide | Daminozide is a highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC50 values of 1.5, 0.55, and 2.1 μM, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC50s > 100 μM). Daminozide is known to retard plant growth and was widely used in the 1960s for agricultural and horticultural applications to control plant size and fruit ripening before it was withdrawn because of carcinogenicity concerns. Synonyms: Alar; B 995; DMASA; SADH; Succinic Acid; Aminozide; Kylar; DIMG. Grades: >98%. CAS No. 1596-84-5. Molecular formula: C6H12N2O3. Mole weight: 160.17. | |
| Dansyl sarcosine piperidinium salt | Dansyl sarcosine piperidinium salt, a chemical compound utilized in biochemical research, holds a pivotal position in the study of NMDA receptors. Owing to its proficiency in fluorescence detection of glutamate or glycine binding sites on these receptors, it may have the potential to augment the therapeutic treatment of prevalent neurological disorders such as Alzheimer's and Parkinson's. Its multifaceted uses offer researchers the versatility to investigate a host of biological phenomena related to the aforementioned conditions. Synonyms: Dansylsarcosine piperidinium salt; Piperidin-1-ium 2-(5-(dimethylamino)-N-methylnaphthalene-1-sulfonamido)acetate. Grades: ≥95%. CAS No. 72517-44-3. Molecular formula: C20H29N3O4S. Mole weight: 407.53. | |
| D-AP4 | D-AP4 has been found to be an excitatory amino acid receptor antagonist as well as an agonist at the quisqualate-sensitized AP6 site. Synonyms: D-AP4; D AP4; DAP4; D-(-)-2-Amino-4-phosphonobutyric acid. Grades: ≥98% by HPLC. CAS No. 78739-01-2. Molecular formula: C4H10NO5P. Mole weight: 183.10. | |
| Dapagliflozin | Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; BMS 512148. Grades: >98%. CAS No. 461432-26-8. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin Impurity 16 | Dapagliflozin Impurity 16 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1α-Methyl Dapagliflozin; Dapagliflozin Methoxy Pyranose Impurity; (2S,3R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methyl 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-; Methoxy Dapagliflozin. Grades: >95%. CAS No. 714269-57-5. Molecular formula: C22H27ClO7. Mole weight: 438.90. | |
| Dapagliflozin Impurity 17 | Dapagliflozin Impurity 17 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1,4-Dibromo-2-[(4-ethoxyphenyl)methyl]benzene. Grades: >95%. CAS No. 1807632-93-4. Molecular formula: C15H14Br2O. Mole weight: 370.08. | |
| Dapagliflozin Impurity 24 | Dapagliflozin Impurity 24 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol; BMS-639432. Grades: >95%. CAS No. 1204222-85-4. Molecular formula: C21H25ClO7. Mole weight: 424.87. | |
| Dapagliflozin Impurity 3 | Cas No. 1807632-95-6. | |
| Dapagliflozin Ortho Isomer | Dapagliflozin Ortho Isomer is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: CS-0165472. Grades: 95%. CAS No. 2040305-05-1. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Daphnetin dimethyl ether | Daphnetin dimethyl ether is a coumarin isolated from Artemisia caruifolia. Synonyms: 7,8-Dimethoxycoumarin; 7,8-dimethoxychromen-2-one. Grades: 0.98. CAS No. 2445-80-9. Molecular formula: C11H10O4. Mole weight: 206.19. | |
| DAPI dihydrochloride | DAPI is a fluorescent DNA stain that binds to the minor groove of double-stranded DNA with preference for adenine and thymine (AT) rich DNA. DAPI is commonly used in microscopy and flow cytometry. It can be used on either fixed or live cells, although it crosses membranes in live cells less efficiently and demands higher concentrations to be used. Uses: Suitable for dna staining in agarose gels, analysis of changes in dna during apoptosis, detection of mycoplasma, photofootprinting of dna, immunofluorescent staining of cells. Synonyms: DAPI;2-[4-(aminoiminomethyl)phenyl]-1H-indole-6-carboximidamide dihydrochloride. Grades: ≥90%. CAS No. 28718-90-3. Molecular formula: C16H15N5·2HCl. Mole weight: 350.3. | |
| Dapoxetine Impurity 1 | An impurity of Dapoxetine. Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor. Synonyms: 3,4-Dihydro-4-phenyl-2H-benzo[h]chromene. Grades: 95%. CAS No. 94305-25-6. Molecular formula: C19H16O. Mole weight: 260.33. | |
| Dapoxetine Impurity 2 | An impurity of Dapoxetine. Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor. Grades: 95%. CAS No. 2242008-37-1. Molecular formula: C30H31NO2. Mole weight: 437.57. | |
| Dapoxetine Impurity 24 | An impurity of Dapoxetine. Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor. Synonyms: α -[2- (1-Naphthalenyloxy) ethyl]benzenemethanol; 3-(1-Naphthalenyloxy)-1-phenylpropan-1-ol. Grades: 95%. CAS No. 908291-72-5. Molecular formula: C19H18O2. Mole weight: 278.34. | |
| Dapoxetine Impurity 2 hydrochloride | An impurity of Dapoxetine. Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor. Grades: 95%. CAS No. 2242008-38-2. Molecular formula: C30H32NO2Cl. Mole weight: 474.03. | |
| Dapoxetine Impurity 8 | An impurity of Dapoxetine. Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor. Synonyms: Dapoxetine Impurity 004. Grades: 95%. CAS No. 2245197-07-1. Molecular formula: C30H31NO. Mole weight: 421.57. | |
| DAPT | DAPT, also called γ-Secretase Inhibitor IX, is a potent and selective inhibitor of γ-secretase which leads to a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human)). Uses: Differentiation. Synonyms: tert-butyl (2S) -2-[[ (2S) -2-[[2- (3, 5-difluorophenyl) acetyl]amino]propanoyl]amino]-2-phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAPT); C23H26F2N2O4; GSIIX; S2215_Selleck; AC1NSKCB; PubChem22436; GSI-IX; DAPT,GSI-IX; DAPT; DAPT - GSI-IX; MLS006010075; CHEMBL255682; QCR-29; SCHEMBL1360313; DTXSID00415519; AOB33372; DAPT-Supplied by Selleck Chemicals; EBD16444; ZINC1549363; ABP000317; ZINC01549363; AKOS024457209; CS-0264; NCGC00167803-03; (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu; AC-23163; AK477268; BC649954; CJ-24363; HY-13027; KB-57235; SMR004701228; AB0033805; LS-191073; D4257; GSI-IX, 208255-80-5; X7572; W-5319; AB01566837_01; GSI-IX , GSI IX; 208255-80-5; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester; DAPT|N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[(3,5-Difluorophenyl)acetyl]-[l-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester. Grades: 0.98. CAS No. 208255-80-5. Molecular formula: C23H26F2N2O4. Mole weight: 432.46. | |
| Darunavir | Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. Uses: Hiv protease inhibitors. Synonyms: TMC-114; TMC 114; TMC114; Prezista. Grades: ≥98%. CAS No. 206361-99-1. Molecular formula: C27H37N3O7S. Mole weight: 547.67. | |
| Darunavir Ethanolate | Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor, used to treat HIV infection. Uses: Hiv protease inhibitors. Synonyms: Phosphonoformate. Grades: >98%. CAS No. 635728-49-3. Molecular formula: C27H37N3O7S·C2H5OH. Mole weight: 593.73. | |
| Dasatinib N-Oxide | Dasatinib N-Oxide is an oxidative metabolite of Dasatinib (M5 metabolite). Synonyms: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide. Grades: > 95%. CAS No. 910297-52-8. Molecular formula: C22H26ClN7O3S. Mole weight: 504. | |
| Dasotraline | Dasotraline hydrochloride is a metabolite of sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50= 4, 6, and 11 nM, respectively). Synonyms: (1R,4S)-trans-Norsertraline; Norsertraline, (1R,4S)-trans-; (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine. CAS No. 675126-05-3. Molecular formula: C16H15Cl2N. Mole weight: 292.203. | |
| Daunorubicin EP Impurity B | Daunorubicinol, a metabolite of Daunorubicin, is an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Synonyms: 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-((1S)-1-hydroxyethyl)-1-methoxy-, (8S,10S)-; 13-Dihydrodaunorubicin; Duborimycin; Leukaemomycin D; Daunorubicin EP Impurity B (Mixture of Diastereomers); (13S)-13-Dihydrodaunorubicin; (1S,3S)-3,5,12-Trihydroxy-3-[(1S)-1-hydroxyethyl]-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; Daunomycinol; Dihydrodaunomycin; Antibiotic 20-798RP; Daunorubicinol. Grades: >95%. CAS No. 28008-55-1. Molecular formula: C27H31NO10. Mole weight: 529.54. | |
| Daunorubicinol hydrochloride | Daunorubicinol Hydrochloride is a metabolite of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-, hydrochloride, [8S-[8α,8(R*),10α]]-; 13-Dihydrodaunorubicin Hydrochloride; Duborimycin Hydrochloride; Leukaemomycin D Hydrochloride; L-lyxo-Hexopyranoside, 1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-3-(1-hydroxyethyl)-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-, hydrochloride, (1S,3S)-α-; 13-Dihydrodaunomycin hydrochloride; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-[(1S)-1-hydroxyethyl]-1-methoxy-, hydrochloride (1:1), (8S,10S)-; Antibiotic RP 20798; Antibiotic 20798 RP; Dihydrodaunomycin hydrochloride; NSC 180510. Grades: ≥95%. CAS No. 28008-53-9. Molecular formula: C27H32ClNO10. Mole weight: 566.00. | |
| DBCO-PEG4-NHS ester | DBCO-PEG4-NHS ester is PEG derivative used as a cross-linker to react with primary amines. Synonyms: Azadibenzocyclooctyne-PEG4-NHS ester. Grades: >95%. CAS No. 1427004-19-0. Molecular formula: C34H39N3O10. Mole weight: 649.69. | |
| D-β-Homoalanine hydrochloride | D-β-Homoalanine hydrochloride, an amino acid derivative, is of significant interest owing to its multiple applications ranging from peptide synthesis to the development of natural product antibiotics. Research has also been conducted to unveil its potential antiviral and antitumor properties, representing an area of pharmacological significance with far-reaching implications. Synonyms: H-D-Ala-(C#CH2)OH HCl; H-D-β-homoAla-OH HCl; (R)-3-Aminobutanoic acid hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 58610-42-7. Molecular formula: C4H10ClNO2. Mole weight: 139.58. | |
| DBIBB | DBIBB is a non-lipid agonist of LPA2 (EC50 = 0.10 μM) that is a G protein-coupled receptor which plays roles in protecting against radiation-induced cell death and it has no effect at other LPA receptor subtypes. Synonyms: 2-[[[4-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)butyl]amino]sulfonyl]-benzoic acid. Grades: ≥98%. CAS No. 1569309-92-7. Molecular formula: C23H20N2O6S. Mole weight: 452.5. | |
| DC661 | DC661 is an effective palmitoyl-protein thioesterase 1 (PPT1) inhibitor that inhibits autophagy and ACTS as an antilysosomal agent. Compared with hydroxychloroquine (HCQ), DC661 has significant acid hydrolysis and autophagy inhibition. Synonyms: DC661; 1872387-43-3; N-(7-chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine; N1-(7-chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine; dc-661; C31H39Cl2N5; CHEMBL4873725; SCHEMBL19399303; BCP30743; EX-A2963; XZC38743; s8808; ZB1540; AKOS037649041; DC-661; DC 661; AC-35596; BS-16368; HY-111621; CS-0088759; D80814; 7-chloro-N-[6- ({6-[ (7-chloroquinolin-4-yl)amino]hexyl} (methyl)amino)hexyl]quinolin-4-amine. CAS No. 1872387-43-3. Molecular formula: C31H39Cl2N5. Mole weight: 552.58. | |
| DC 838 | DC 838 is a potent human cyclophilin A (CypA) inhibitor. Synonyms: DC 838; DC838; DC-838; 1-N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-N,3-N-diethylpiperidine-1,3-dicarboxamide. Grades: 99%. CAS No. 508186-08-1. Molecular formula: C27H29N5O4. Mole weight: 487.55. | |
| DCU | Dicloralurea, a veterinary food additive, could restrain the formation of methane in herbicide ruminants for behaving as a growth stimulant. Uses: Dicloralurea is commonly used as a veterinary food additive for it could restrain the formation of methane in herbicide ruminants for behaving as a growth stimulant. Synonyms: 1,3-bis(1-hydroxy-2,2,2-trichloroethyl)urea;1,3-bis(1-hydroxy-2,2,2-trichloroethyl)urea[qr];1,3-bis(2,2,2-trichloro-1-hydroxyethyl)-ure;1,3-bis(2,2,2-trichloro-1-hydroxyethyl)urea;1,3-bis(2,2,2-trichloro-1-hydroxyethyl)urea[qr];cragdcu-73w. Grades: 95%. CAS No. 116-52-9. Molecular formula: C5H6Cl6N2O3. Mole weight: 354.83. | |
| DDD85646 | DDD85646 is a moderately bioavailable pyrazole sulphonamide inhibitor of T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. Synonyms: IMP-366; 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide. Grades: ≥98%. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.4. | |
| D-Desthiobiotin | D-Desthiobiotin is an analogue of Biotin and a protein cross-linking agent. It is used in the preparation of agarose matrices for affinity-based isolation of streptavidin-fluorophore conjugates. Synonyms: Desthiobiotin; Dethiobiotin; d-Dethiobiotin; (+)-Dethiobiotin; ε-(4-Methyl-5-imidazolidone-2)caproic Acid; (4R,5S)-5-Methyl-2-oxo-4-imidazolidinehexanoic Acid; (4R-cis)-5-methyl-2-oxo-4-Imidazolidinehexanoic Acid; 4-Methyl-5-(ω-carboxyamyl)imidazolidone; 5-Methyl-2-oxo-4-imidazolidinecaproic Acid. Grades: ≥95% by HPLC. CAS No. 533-48-2. Molecular formula: C10H18N2O3. Mole weight: 214.26. | |
| Deacetyl ganoderic acid F | Deacetyl ganoderic acid F, a natural triterpenoid compound obtained from the Ganoderma lucidum, displays an array spectrum of pharmacological activities, particularly antitumor, immunomodulatory, and antiviral properties, to name a few. Moreover, Deacetyl ganoderic acid F exhibits effective outcomes for treating liver-associated diseases, for instance, hepatic fibrosis, liver cancer, and hepatitis, thereby, promising a potential therapeutic agent for liver dysfunctions. Synonyms: Deacetyl ganoderic acid F; Ganoderic acid F, deacetyl-; (12beta)-12-Hydroxy-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid. Grades: >98%. CAS No. 100665-44-9. Molecular formula: C30H40O8. Mole weight: 528.6. | |
| Deapi-platycodin D3 | Deapi-platycodin D3 is a triterpenoid compound found in the roots of Platycodon grandiflorum A. de Candolle (APG), of which the aqueous extract is used as a therapy of inflammatory pulmonary diseases. Synonyms: 2beta,16alpha,23,24-Tetrahydroxy-3beta-(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyloxy)-5alpha-oleana-12-ene-28-oic acid 2-O-(4-O-beta-D-xylopyranosyl-alpha-L-rhamnopyranosyl)-alpha-L-arabinopyranosyl ester. Grades: >98%. CAS No. 67884-05-3. Molecular formula: C58H94O29. Mole weight: 1255.361. | |
| Decapeptide-12 | Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells. It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. Synonyms: L-Tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl-L-tyrosine. Grades: 98%. CAS No. 137665-91-9. Molecular formula: C65H90N18O17. Mole weight: 1395.5. | |
| Decitabine | Decitabine is a potent inhibitor of DNA methylation, used to treat myelodysplastic syndrome (MDS). Synonyms: 5-Aza-2'-deoxycytidine; 5-Azadeoxycytidine; Dacogen; Deoxycytidine, 5-aza-2'-deoxycytidine. Grades: ≥ 98% by HPLC. CAS No. 2353-33-5. Molecular formula: C8H12N4O4. Mole weight: 228.21. | |
| Decursin | Decursin is a coumarin from The roots of Peucedanum ostruthium. Coumarins, such as decursinol and decursin, are known to be the major compounds of A. gigas. Angelica gigas roots have been widely used traditionally in Korean herbal medicine not only for the treatment of anaemia, but also as a sedative, an anodyne and a tonic. Studies have shown that decursin inhibits VEGF-mediated inner BRB breakdown through suppression of VEGFR-2 signaling pathway. And decursin is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. Uses: Enzyme activators. Synonyms: 2-Butenoic acid, 3-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester (9CI); 2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester, (S)-; Crotonic acid, 3-methyl-, ester with 7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one, (+)- (8CI); 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv. Grades: > 98%. CAS No. 5928-25-6. Molecular formula: C19H20O5. Mole weight: 328.36. | |
| Decursinol | Decursinol is a coumarin isolated from Angelica gigas. It shows anti-tumor and anti-metastasis activity. Synonyms: (+)-Decursinol. Grades: 98%. CAS No. 23458-02-8. Molecular formula: C14H14O4. Mole weight: 246.26. | |
| Decyl b-D-maltopyranoside | Decyl b-D-maltopyranoside is a nonionic surfactant that is commonly used to solubilize and stabilize membrane proteins. Synonyms: Decyl maltoside; n-Decyl-beta-D-maltoside; decyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside. Grades: >99%. CAS No. 82494-09-5. Molecular formula: C22H42O11. Mole weight: 482.56. | |
| Decynium 22 | Decynium 22 is a potent inhibitor of PMAT and has been found to exhibit activities in inducing apoptosis in cerebellar granule neurons (CGNs). Synonyms: 1-Ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]quinolinium iodide. Grades: ≥98% by HPLC. CAS No. 977-96-8. Molecular formula: C23H23IN2. Mole weight: 454.35. | |
| Defensamide | Defensamide (MHP) can modulate the innate epidermal immune response by potentiating SPHK1 activity and inducing cAMP production. It is an activator of sphingosine kinase (SPHK1). Synonyms: MHP; N-Hexanoyltyrosine methyl ester; UNII-8GJP2KSJ0T; 8GJP2KSJ0T. CAS No. 1104874-94-3. Molecular formula: C16H23NO4. Mole weight: 293.36. | |
| Defensin HNP-1 (human) trifluoroacetate salt | Defensin HNP-1 is a peptide secreted by polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It completely inhibits secretion of the exotoxin superantigen TSS toxin-1 (TSST-1) from S. aureus when used at a concentration of 50 ng/ml and inhibits anthrax lethal toxin. Synonyms: DEFA1 Protein; α-Defensin 1; Human Neutrophil Peptide 1; Neutrophil Defensin 1. Grades: ≥95%. Molecular formula: C150H222N44O38S6·xCF3COOH. Mole weight: 3442.04. | |
| Defensin HNP-3 (human) trifluoroacetate salt | Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV). Synonyms: DEFA3 Protein; α-Defensin 3; Human Neutrophil Peptide 3; Neutrophil Defensin. Grades: ≥95%. Molecular formula: C151H222N44O40S6·xCF3COOH. Mole weight: 3486.05. | |
| Deferasirox Fe3(addition) chelate | Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. Synonyms: Exjade Fe3+ chelate. Grades: >98%. CAS No. 554435-83-5. Molecular formula: C21H12FeN3O4. Mole weight: 426.18. | |
| Defluoro Aprepitant | A metabolite of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Synonyms: Aprepitant EP Impurity A; 5-([(2R,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-phenyl morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one. Grades: > 95%. CAS No. 170729-76-7. Molecular formula: C23H22F6N4O3. Mole weight: 516.45. | |
| Defluoro Levofloxacin | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (3S)-2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Levofloxacin Related Compound F (USP). Grades: > 95%. CAS No. 117620-85-6. Molecular formula: C18H21N3O4. Mole weight: 343.39. | |
| Defluoro Linezolid | Defluoro Linezolid is an impurity of Linezolid, which is an antibiotic used for the treatment of infections caused by Gram-positive bacteria. Synonyms: (S)-N-{[3-(4-Morpholinophenyl)-2-oxooxazolidin-5-yl]methyl}acetamide; Desfluoro linezolid; N-[[(5S)-3-[4-(4-Morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[[(5S)-3-[4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Desfluorolinezolid; 1-({[(5S)-3-(p-Morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}amino)-1-ethanone. Grades: ≥95%. CAS No. 556801-15-1. Molecular formula: C16H21N3O4. Mole weight: 319.36. | |
| Degarelix | Degarelix acetate is a reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist. Degarelix reduces the secretion of luteinizing hormone (LH) and testosterone via blocking GnRHR. Degarelix can be used for the treatment of prostate cancer. Synonyms: Degarelix; Firmagon; FE-200486; FE 200486; FE200486; ASP-3550; ASP 3550; ASP3550; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2. Grades: >98%. CAS No. 214766-78-6. Molecular formula: C82H103ClN18O16. Mole weight: 1632.286. | |
| Degarelix acetate | Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist. It decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats when administered at a dose of 1 mg/kg per month. Formulations containing degarelix have been used in the treatment of advanced prostate cancer. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-((S)-dihydroorotamido)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetic acid; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1); FE 200486; Gonax. Grades: ≥98%. CAS No. 934016-19-0. Molecular formula: C82H103ClN18O16.C2H4O2. Mole weight: 1692.31. | |
| Degarelix acetate hydrate | Degarelix acetate is a synthetic peptide that acts as a gonadotrophin-releasing hormone (GnRH) antagonist. Degarelix targets GnRH receptors in the pituitary gland, resulting in reduction of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and suppression of testosterone. Synonyms: FE-200486; FE 200486; FE200486; ASP-3550; ASP 3550; ASP3550. CAS No. 934246-14-7. Molecular formula: C84H109ClN18O19. Mole weight: 1710.32. | |
| Dehydroandrographolide succinate | Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral properties. Synonyms: Dehydroandrographolide succinate|786593-06-4|DEHYDROANDROGRAPHOLide SUCCINATE|UNII-0X50BP49M1|0X50BP49M1|4- [ [ (1R, 2R, 4aR, 5R, 8aS) -2- (3-carboxypropanoyloxy) -1, 4a-di methyl -6- methyl ide ne -5- [ (E) -2- (5-oxo-2H-furan-4-yl) ethenyl] -3, 4, 5, 7, 8, 8a-hexahydro-2H-naphthalen-1-yl] methoxy] -4-oxobutanoic acid|CHEMBL3040746|SCHEMBL14958695|1 4-Deoxy-11, 12-dide hydroandrographolide bis (hemisuccinate) |HY-N0677|ZINC4273374|MFCD10566633|s9224 |AKOS037515374|CCG-269928|AC-34800|BS-45359|Butane dioic acid, 1-(((1R,2R,4aR,5R,8aS)-2-(3-carboxy-1-oxopropoxy)-5-((1E)-2-(2,5-dihydro-2-oxo-3-furanyl)ethenyl)decahydro-1,4a-dimethyl-6-methylene-1-naphthalenyl)methyl) ester|CS-0009708|4-(((1R,2R,4aR,5R,8aS)-2-((3-Carboxypropanoyl)oxy)-1,4a-dimethyl-6-methylene-5-((E)-2-(2-oxo-2,5-dihydrofuran-3-yl)vinyl)decahydronaphthalen-1-yl)methoxy)-4-oxobutanoic acid. Grades: 99.88%. CAS No. 786593-06-4. Molecular formula: C28H36O10. Mole weight: 532.58. | |
| Dehydrocholic Acid | Dehydrocholic Acid is a derivative of Cholic Acid and manufactured by the oxidation of cholic acid. It is produced by choleretic and isolated from liver cells. It acts as a hydrocholeretic, increasing bile output to clear increased bile acid load. Uses: Dehydrocholic acts as a hydrocholeretic, increasing bile output to clear increased bile acid load. Synonyms: Decholin; Dehystolin; Oxycholin; Ketocholanic acid; Felacrinos; Sanocholen; 3,7,12-Trioxocholanic acid. Grades: >98%. CAS No. 81-23-2. Molecular formula: C24H34O5. Mole weight: 402.52. | |
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