BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Phenylboronic Acid-[13C6] | Phenylboronic Acid-[13C6] is an isotope labelled compound of Phenylboronic Acid. Phenylboronic Acid is a compound used in organic synthesis of various pharmaceutical goods. Alternative Names: B-Phenylboronic Acid-13C6; Dihydroxyphenylborane-13C6; Phenylboric Acid-13C6; Phenylboronic Acid-13C6; Phenyldihydroxyborane-13C6. Grades: 98% by CP; 98% atom 13C. Molecular formula: [13C]6H7BO2. Mole weight: 127.89. |  |
| Phenyl-[d5]-acetate | An isotopic form of Phenyl Acetate. Phenyl Acetate is a metabolite of Phenylbutyrate (PB), useful in the treatment of neuroblastoma and lung cancer. Alternative Names: Phenyl-d5 Acetic Acid Ester; Acetoxybenzene-d5; NSC 27795-d5. Grades: 98% atom D. CAS No. 22705-26-6. Molecular formula: C8H3D5O2. Mole weight: 141.18. | |
| Phenylsilane-[d3] | Phenylsilane-d3 can be used for isotopic effect in various experiments. Alternative Names: Phenylsilane-α-d3; Trideutero(phenyl)silane. CAS No. 18164-03-9. Molecular formula: C6H5D3Si. Mole weight: 111.23. | |
| Phenytoin | Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels. Uses: Anticonvulsants. Alternative Names: phenytoin;5,5-DIPHENYLHYDANTOIN;57-41-0;Diphenylhydantoin;Dilantin;5,5-diphenylimidazolidine-2,4-dione;Phenytoine;Zentropil;Epamin;Lepitoin;Dihydantoin;Aleviatin;Dilabid;Diphantoin;Diphenylan;Diphedan;Fenylepsin;Phentytoin;Sodanton;Difenin;Dihycon;Lehydan;Diphenylhydatanoin;Dantoinal;Di-Hydan;Dilantine;Dillantin;Diphenine;Diphentyn;Ditoinate;Elepsindon;Epilantin;Fenitoina;Fenytoine;Hidantilo;Hidan. Grades: >98%. CAS No. 57-41-0. Molecular formula: C21H28O2. Mole weight: 312.4. | |
| Phe-Phe-OMe HCl | Phe-Phe-OMe HCl is employed as a reagent used in the preparation of polymer nanoparticles containing hydrophobic dipeptide for inhibition of amyloid-β fibrillation. Alternative Names: H-Phe-Phe-OMe HCl; Methyl L-phenylalanyl-L-phenylalaninate hydrochloride; L-Phenylalanyl-L-phenylalanine methyl ester hydrochloride; (S)-Methyl 2-((S)-2-amino-3-phenylpropanamido)-3-phenylpropanoate hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 38017-65-1. Molecular formula: C19H23ClN2O3. Mole weight: 362.86. | |
| PHE-PRO | A substrate for skin fibroblast prolidase. Alternative Names: L-phenylalanyl-L-proline; Phenylalanylproline; L-Phe-L-Pro; (S)-1-((S)-2-Amino-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid. Grades: >99%. CAS No. 7669-65-0. Molecular formula: C14H18N2O3. Mole weight: 262.30. | |
| Phillyrin | Phillyrin is a natural lignan compound that has anti-obesity effects. It can reduce tumor necrosis factor secreted by macrophages, which plays an important role in fat adipocyte dysfunction. Alternative Names: β-D-Glucopyranoside, 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl; 4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl β-D-glucopyranoside; Phyllyrin; β-D-Glucopyranoside, 4-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl, [1S-(1α,3aα,4β,6aα)]-; Phillygenin β-D-glucopyranoside; [1S-(1α,3aα,4β,6aα)]-4-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl-β-D-Glucopyranoside; Phillyroside. Grades: ≥95%. CAS No. 487-41-2. Molecular formula: C27H34O11. Mole weight: 534.55. | |
| Phleomycin D1 | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 12.5-25 μg/mL. It inhibits airy entity carcinoma in mice with IC50 of 0.31 μg/mL. Alternative Names: Zeocin; Zeocine; (7R)-N1-[4-[[Amino(imino)methyl]amino]butyl]-7,8-dihydrobleomycinamide; Bleomycinamide, N1-[4-[(aminoiminomethyl)amino]butyl]-7,8-dihydro-. Grades: 95%. CAS No. 11031-11-1. Molecular formula: C55H86N20O21S2. Mole weight: 1427.52. | |
| Phloretin | Phloretin, a type of natural phenol found in the peels of apples, is a dihydrochalcone that shows beneficial effects on diabetes. Phloretin has whitening, freckle removal, anti-aging, strong antioxidant, and photoprotective effects. It can also inhibit the activity of matrix metalloproteinase (MMP-1) and elastase, which can degrade skin connective tissue and play an important role in the process of skin photoaging. Phloretin has excellent immunosuppressive and anti-inflammatory effects. Phloretin can significantly inhibit the levels of nitrogen oxide, prostaglandin E2, IL-6, TNF-α, iNOS and COX-2, inhibit the nuclear translocation of NF-JB subunit p65 protein, and reduce phosphorylation in the MAPK pathway. It can be used in facial masks, skin creams, lotions and essences. Uses: Antimicrobial activity. Alternative Names: Dihydronaringenin; NSC 407292; NSC-407292; NSC407292; RJC 02792; RJC02792; RJC-02792; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone; Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-; 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone; 2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone; Dihydronaringenin; Naringenin dihydrochalcone; NSC 407292; Phloretol; RJC 02792; α,β-Dihydrochalconaringenin; β-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone; β-(p-Hydroxyphenyl)phloropropiophenone. Grades: >98%. CAS No. 60-82-2. Molecular formula: C15H14O5. Mole weight: 274.27 | |
| Phlorin | Phlorin isolated from the herbs of Thymus vulgaris. Alternative Names: Phloroglucinol 1-O-beta-D-glucoside. Grades: 0.98. CAS No. 28217-60-9. Molecular formula: C12H16O8. Mole weight: 288.3. | |
| Phlorizin | Phlorizin is a 2'-glucoside of phloretin. It belongs to the group of dihydrochalcones, a type of flavonoids. Phlorizin is found in the herbs of Prunus armeniaca L. Phlorizin has many important biological activities such as lowering blood sugar, improving memory, anti-oxidation, anti-cancer, etc., and has a wide range of application prospects in the development of new drugs and natural health foods. Uses: Peroxynitrite scavenging / antifeedant. Alternative Names: 1-[2-(b-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; Floridzin; Phloretin 2-b-D-glucopyranoside. Grades: >98%. CAS No. 60-81-1. Molecular formula: C21H24O10. Mole weight: 436.41. | |
| Phomopsin A | It is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids. It is a potent mycotoxin produced by the fungus, phomopsis leptostromiformis. It is an important bioprobe for understanding cellular structural proteins. It selectively binds to the dimeric tubulin at the overlap of vinblastine and maytansine, inhibits the formation of the microtubule spindle to block cell division. Alternative Names: 2-Oxa-5,8-diazabicyclo[10.3.1]hexadecane, cyclic peptide deriv.; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(2E)-2,3-didehydroisoleucyl-2,3-didehydro-aspartic acid, cyclic (15→3)-ether; NSC 381839; PMSA; Phomopsin. Grades: >98% by HPLC. CAS No. 64925-80-0. Molecular formula: C36H45ClN6O12. Mole weight: 789.23. | |
| Phospho-L-Tyrosine Disodium Salt | Phospho-L-Tyrosine Disodium Salt is a versatile reagent for the synthesis of other chemicals, such as vitamins, drugs and pesticides. It can also be used to make high quality, useful intermediates for chemical reactions or as a reaction component. Alternative Names: Disodium O-phosphonato-L-tyrosine. CAS No. 1610350-91-8. Molecular formula: C9H10NNa2O6P. Mole weight: 305.13. | |
| Phosphonomycin Calcium salt | It is produced by the strain of Str. fradiae NRRL-3417, Str. viridchromogenes NRRL-3413. It's an antibiotic that contains phosphorus. It has anti-gram positive bacterial and negative bacterial activity, inorganic phosphorus and sodium chloride can reduce its activity. It has protective effect on mice infected with Staphylococcus aureus, Salmonella typhi and Salmonella paratyphi B by oral administration. Alternative Names: (-)-Phosphonomycin Calcium salt; Calcium fosfomycin; fosfomycin calcium; Fosmicin; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1); Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-; Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1); Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-. Grades: 98%. CAS No. 26016-98-8. Molecular formula: C3H5O4P.Ca. Mole weight: 176.12. | |
| Phthalic acid-[3,4,5,6-d4] | Phthalic acid-[3,4,5,6-d4]. Uses: Organic reagent used to synthesize phthalates. Alternative Names: Phthalic acid-phenyl-d4; 1,2-(Benzene-d4)dicarboxylic Acid; NSC 5348-d4; Sunftal 20-d4; o-(Benzene-d4)dicarboxylic Acid; o-Carboxybenzoic Acid-d4; o-Dicarboxybenzene-d4. Grades: ≥98% by CP; ≥98% atom D. CAS No. 87976-26-9. Molecular formula: C8H2D4O4. Mole weight: 170.16. | |
| Phthaloyl-L-isoleucine | Phthaloyl-L-isoleucine. Alternative Names: Pht-L-Ile-OH; (2S,3S)-2-(1,3-Dioxoisoindolin-2-Yl)-3-Methylpentanoic Acid. Grades: ≥ 97% (HPLC). CAS No. 29588-88-3. Molecular formula: C14H15NO4. Mole weight: 261.27. | |
| p-Hydroxyphenethyl trans-ferulate | p-Hydroxyphenethyl trans-ferulate isolated from the roots of Angelica sinensis. Alternative Names: 4-Hydroxyphenethyl trans-ferulate. Grades: 0.98. CAS No. 84873-15-4. Molecular formula: C18H18O5. Mole weight: 314.3. | |
| p-Hydroxyphenylethyl p-coumarate | p-Hydroxyphenylethyl p-coumarate. Grades: 98.0%. CAS No. 149030-02-4. Molecular formula: C17H16O4. | |
| (+)-Phyllodulcin | (+)-Phyllodulcin is a dihydroisocoumarin found in Hydrangea macrophylla and Hydrangea serrata. (+)-Phyllodulcin can be used as a sweetener. Alternative Names: (3R)-3-(3-Hydroxy-4-methoxyphenyl)-8-hydroxyisochroman-1-one; (3R)-3β-(3-Hydroxy-4-methoxyphenyl)-8-hydroxy-3,4-dihydro-1H-2-benzopyran-1-one; (3R)-Phyllodulcin; Phyllodulcin. CAS No. 21499-23-0. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Physcion | Physcion is an anthraquinone from roots of Rheum officinale Baill.It has also shown anti-fungal activity against barley powdery mildew and cucumber powdery mildew, more efficiently in the latter case than treatments with fenarimol and polyoxin B. Uses: Anti-inflammatory; antifungal; anti-cancer activities; anti-proliferative. Alternative Names: Physcione; Rheochrysidin; Emodin 3-methyl ether; 1,8-Dihydroxy-3-methoxy-6-methylanthraquinone; NSC 251670. Grades: >98%. CAS No. 521-61-9. Molecular formula: C16H12O5. Mole weight: 284.26. | |
| Phytol | Phytol isolated from the leaves of Black tea. It attenuates the inflammatory response by inhibiting neutrophil migration, which is partly caused by reduction in IL-1β and TNF-α levels and oxidative stress. Uses: Antimycobacterial; anti-tumor; anti-cancer ;anxiolytic activities. Alternative Names: (2E,7R,11R)-3,7,11,15-Tetramethyl-2-hexadecen-1-ol; 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-, [R-[R*,R*-(E)]]-; (7R,11R,2E)-Phytol; (7R,11R,E)-3,7,11,15-Tetramethylhexadec-2-en-1-ol; (E)-Phytol; (E,R,R)-Phytol; trans-Phytol; 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-, (2E,7R,11R)-. Grades: 98.0%. CAS No. 150-86-7. Molecular formula: C20H40O. Mole weight: 296.53. | |
| Phytolaccoside B | Phytolaccoside B isolated from the roots of Phytolacca acinosa Roxb. Uses: Antifungal. Alternative Names: (4R,20S)-3β-(β-D-Xylopyranosyloxy)-2β,23-dihydroxyolean-12-ene-28,30-dioic acid 30-methyl ester;2β,23-Dihydroxy-3β-(β-D-xylopyranosyloxy)oleana-12-ene-28,30-dioic acid 30-methyl ester. Grades: 98%. CAS No. 60820-94-2. Molecular formula: C36H56O11. Mole weight: 664.82. | |
| Phytone | Hexahydrofarnesyl acetone is a fragnance agent commonly used in jasmine compositions. Alternative Names: 6,10,14-trimethyl-2-pentadecanone; 6,10,14-trimethylpentadecan-2-one. Grades: > 98 %. CAS No. 502-69-2. Molecular formula: C18H36O. Mole weight: 268.48. | |
| Piceatannol | Piceatannol, a natural stilbene, is a selective Syk inhibitor and ~10-fold selectivity versus Lyn. Uses: Antioxidant, and anti-inflammatory activities; antitumor activity. Alternative Names: Piceatannol; NSC 622471; NSC-622471; NSC622471. Grades: >98%. CAS No. 10083-24-6. Molecular formula: C14H12O4. Mole weight: 244.24. | |
| Pidotimod | Pidotimod is a synthetic dipeptide molecule with biological and immunological activity on both the adaptive and the innate immune responses. Alternative Names: Pidotomod; PGT/1A; PGT 1A; PGT1A; PGT-1A. Grades: >98%. CAS No. 121808-62-6. Molecular formula: C9H12N2O4S. Mole weight: 244.27. | |
| Pidotimod Impurity (L-Thiaproline) | Timonacic is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities. Acting on cellular membranes of malignant cells through an unknown mechanism, timonacic may induce malignant cells to revert back to an untransformed state. This agent may also restore contact inhibition, a phenomenon characterized by the paracrine inhibition of mitosis following the formation of a critical cell mass, presumably the result of cell-to-cell signal transfer. Timonacic may also produce antioxidant effects secondary to its release of cysteine and restoration of glutathione concentrations. Alternative Names: Timonacic; L-Thiazolidine-4-carboxylic acid; T4C. Grades: ≥ 98.5% (assay). CAS No. 34592-47-7. Molecular formula: C4H7NO2S. Mole weight: 133.17. | |
| Pimaric acid | Pimaric acid isolated from the herbs of Aralia cordata. It can be exploited for therapeutic application in oral microbial infections. Uses: Anti-atherosclerotic activity; antibacterial, anti-biofilm and anti-inflammatory potency. Alternative Names: 1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahyd. Grades: 75%. CAS No. 127-27-5. Molecular formula: C20H30O2. Mole weight: 302.5. | |
| Pimaricin | It is produced by the strain of Str. natalensis NRRL 2651, Str. gilvosporeus. It's a polyene macrolide antibiotic with strong antifungal effect. Alternative Names: Myprozine; Natamycin; Delvolan; Delvocid; Natacyn; Natafucin; Pimafucin; Pimafugin; Tennecetin; Synogil; Antibiotic A-5283; Natamicina; 16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure. Grades: ≥98%. CAS No. 7681-93-8. Molecular formula: C33H47NO13. Mole weight: 665.73. | |
| Pinobanksin | Pinobanksin is a flavonoid isolated from the barks of Pinus koraiensis. Uses: Antimutagenic properties. Alternative Names: 3,5,7-trihydroxyflavanone; (2R,3R)-pinobanksin. Grades: 99%. CAS No. 548-82-3. Molecular formula: C15H12O5. Mole weight: 272.26. | |
| Pinocembrin | Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia / reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Alternative Names: Dihydrochrysin; Galangin flavanone; (+)-Pinocembrin; (S)-5,7-dihydroxy-2-phenylchroman-4-one; (2S)-pinocembrin. Grades: ≥ 95 % (HPLC). CAS No. 480-39-7. Molecular formula: C15H12O4. Mole weight: 256.25. | |
| Pinoresinol | Pinoresinol isolated from the bark of Eucommia ulmoides Oliver. It causes an upregulation of the CDK inhibitor p21 both at mRNA and protein levels, owing to Pinoresinol reducing proliferation and induce differentiation on HL60 cells. Uses: Antiinflammatory. Alternative Names: (+)-PINORESINOL; (-)-4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol);(3aS,6aS)-3a,4,6,6a-Tetrahydro-3β,6β-bis(4-hydroxy-3-methoxyphenyl)-1H,3H-furo[3,4-c]furan. Grades: 0.985. CAS No. 487-36-5. Molecular formula: C20H22O6. Mole weight: 358.4. | |
| Pinoresinol Diglucoside | Pinoresinol diglucoside is an important antihypertensive compound. Pinoresinol diglucoside is screened as a putative α-glucosidase inhibiting compound. Uses: Antihypertensive. Alternative Names: [(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxy-4,1-phenylene) bis-β-D-glucopyranoside; β-D-Glucopyranoside, (tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis(2-methoxy-4,1-phenylene) bis-, [1S-(1α,3aα,4α,6aα)]-; (+)-Pinoresinol di-O-β-D-glucopyranoside; (+)-Pinoresinol di-β-D-glucopyranoside; Pinoresinol di-β-D-glucoside. Grades: >98%. CAS No. 63902-38-5. Molecular formula: C32H42O16. Mole weight: 682.67. | |
| Piperacillin | An extended spectrum beta-lactam antibiotic and resistant to many beta-lactamases. Uses: Anti-bacterial agents. Alternative Names: CL 227193; Isipen; Pentcillin; Pipracil; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-; 6α-[[(R)-(4-Ethyl-2,3-dioxo-1-piperazinylcarbonylamino)phenylacetyl]amino]penicillanic acid; 6α-[[(R)-α-Oxo-β-[[(2,3-dioxo-4-ethyl-1-piperazinyl)carbonyl]amino]phenethyl]amino]penicillanic acid; PIPC. Grades: 97%. CAS No. 61477-96-1. Molecular formula: C23H27N5O7S. Mole weight: 517.55. | |
| Piperacillin sodium | Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. Uses: Anti-bacterial agents. Alternative Names: CL227193; CL 227193; CL-227193. Grades: >98%. CAS No. 59703-84-3. Molecular formula: C23H27N5O7SNa. Mole weight: 539.54. | |
| Piperine | Piperine (1-Piperoylpiperidine) is an alkaloid isolated from black pepper, activating transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 μM) and modulates GABAA receptors (EC50s = 43-60 μM). It is used in some traditional medicines. Piperine is used as a spicy raw material in the food industry and has a sterilization effect. Uses: Ingredient of health care products. Alternative Names: (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one. Grades: ≥ 98 %. CAS No. 94-62-2. Molecular formula: C17H19NO3. Mole weight: 285.34. | |
| PIPERLONGUMINE | Piperlongumine, also known as Piplartine , is a biologically active alkaloid / amide from peppers, as from long pepper (Piper longum L. - Piperaceae). Long pepper is one of the most widely used in Ayurvedic medicine, which is used to treat many diseases, including tumors. The reported pharmacological activities of piplartine include cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, and schistosomicidal activities. Among the multiple pharmacological effects of piplartine, its anticancer property is the most promising. Therefore, the preclinical anticancer potential of piplartine has been extensively investigated, which recently resulted in one patent. This compound is selectively cytotoxic against cancer cells by induction of oxidative stress, induces genotoxicity, as an alternative strategy to killing tumor cells, has excellent oral bioavailability in mice, inhibits tumor growth in mice, and presents only weak systemic toxicity. Alternative Names: Piplartine; 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone; (E)-5,6-Dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)-pyridinone; Piplartin; (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one; NSC-794671. Grades: ≥98%. CAS No. 2006 | |
| Piperlonguminine | Piperlonguminine is an alkaloid isolated from Piper longum. It exhibits neuroprotective activity in rat plasma, indicating its potential to treat Alzheimer's disease. Alternative Names: N-Isobutylpiperamide; NSC 125178; (E,E)-Piperlonguminine; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide. Grades: ≥98%. CAS No. 5950-12-9. Molecular formula: C16H19NO3. Mole weight: 273.3. | |
| Pirlimycin | A semi-synthetic lincosamide prepared from clindamycin by hydrolysing the propyl N-methylproline and re-annealing a 4-ethylpipecolic acid. It is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans by binding to the 23S ribosomal subunit, blocking protein synthesis. Alternative Names: U-57930E; methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside. Grades: 95%. CAS No. 79548-73-5. Molecular formula: C17H31ClN2O5S. Mole weight: 410.96. | |
| Pirlimycin Hydrochloride | A salt of the semi-synthetic tetracycline analogue, pirlimycin. It is a broad spectrum lincosaminide antibiotic with activity against anaerobic bacteria and protozoans by binding to the 23S ribosomal subunit, blocking protein synthesis. It is also an impurity of Clindamycin. Alternative Names: Pirsue; U 57930E; (2S-cis)-methyl 7-Chloro-6,7,8-trideoxy-6-[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside Monohydrochloride. Grades: >99% by HPLC. CAS No. 78822-40-9. Molecular formula: C17H31ClN2O5S.HCl. Mole weight: 447.42. | |
| Pisatin | Pisatin is a phenolic compound synthesized by pea. Pisatin was the first phytoalexin to be purified and chemically identified. Alternative Names: 3-hydroxy-7-methoxy-4',5'-methylenedioxy-chromanocoumarane;(6aS)-3-Methoxy-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6aα(12aαH)-ol. Grades: >98%. CAS No. 20186-22-5. Molecular formula: C17H14O6. Mole weight: 314.3. | |
| Piscidinol A | Isomedicarpin is a natural triterpenoid found in the bark of Phellodendron chinense, it shows potent cytotoxic activity against P388 and KB cells. Uses: Cytotoxic. Alternative Names: Lanost-7-en-3-one,23,24,25-trihydroxy-, (13a,14b,17a,20S,23R,24S)-. Grades: >95%. CAS No. 100198-09-2. Molecular formula: C30H50O4. Mole weight: 474.7. | |
| Pitavastatin calcium | Pitavastatin calcium is a novel member of the medication class of statins. Alternative Names: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt; Flovas; Livalo; NK 104; NK 104 (acid); Pitava 1; Pitavastatin Hemicalcium; Pitavastatin Calcium Salt; calcium (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Nisvastatin; NK-104; P 872441; P-872441; P872441. Grades: 96%. CAS No. 147526-32-7. Molecular formula: C50H46CaF2N2O8. Mole weight: 880.98. | |
| Pladienolide B | a potent pre-mRNA splicing inhibitor. Pladienolide B has shown strong inhibitory effect against activity and growth of various cell lines via targeting SF3b. Alternative Names: (3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-acetoxy-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide; [(2~{S},3~{S},4~{E},6~{S},7~{R},10~{R})-3,7-dimethyl-2-[(2~{E},4~{E},6~{S})-6-methyl-7-[(2~{R},3~{R})-3-[(2~{R},3~{S})-3-oxidanylpentan-2-yl]oxiran-2-yl]hepta-2,4-dien-2-yl]-7,10-bis(oxidanyl)-12-oxidanylidene-1-oxacyclododec-4-en-6-yl] ethanoate; Pla-B, 5. Grades: ≥95% by HPLC. CAS No. 445493-23-2. Molecular formula: C30H48O8. Mole weight: 536.71. | |
| Pladienolide D | Pladienolide D is an antitumor macrolide produced by Streptomyces platensis. CAS No. 445487-91-2. Molecular formula: C30H48O9. Mole weight: 552.7. | |
| Plantamajoside | Plantamajoside, which is found in the herb of Plantago depressa Willd, exhibits antibacterial activity against Escherichia coli, Staphylococcus aureus and several plant pathogenic bacteria. Besides, Plantamajoside has protective activities against Cadmium-induced renal injury. Uses: Anti-hepatotoxic / anti-inflammatory / antinociceptive. Alternative Names: β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-β-D-glucopyranosyl-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]; β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-β-D-glucopyranosyl-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate], (E)-; Plantamoside; Purpureaside A. Grades: >98%. CAS No. 104777-68-6. Molecular formula: C29H36O16. Mole weight: 640.59. | |
| Plantaricin-149 | Plantaricin-149 is an antimicrobial peptide found in Lactobacillus plantarum NRIC 149, and has antibacterial activity. Grades: >98%. CAS No. 155421-98-0. | |
| Plantaricin 163 | Plantaricin 163 is an antibacterial peptide isolated from Lactobacillus plantarum 163. It has activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: Val-Phe-His-Ala-Tyr-Ser-Ala-Arg-Gly-Asn-Tyr-Tyr-Gly-Asn-Cys-Pro-Ala-Asn-Trp-Pro-Ser-Cys-Arg-Asn-Asn-Tyr-Lys-Ser-Ala-Gly-Gly-Lys. | |
| Plantaricin 423 | Plantaricin 423 is an antimicrobial peptide found in Lactobacillus plantarum 423, and has antibacterial activity. Grades: >98%. CAS No. 183681-68-7. | |
| Plantaricin A | Plantaricin A is an antimicrobial peptide found in Lactobacillus plantarum C11, WCFS1, V90. It has anti-gram-positive bacteria, gram-negative bacteria and Cancer cells activity. Alternative Names: H-Ala-Tyr-Ser-Leu-Gln-Met-Gly-Ala-Thr-Ala-Ile-Lys-Gln-Val-Lys-Lys-Leu-Phe-Lys-Lys-Trp-Gly-Trp-OH; L-alanyl-L-tyrosyl-L-seryl-L-leucyl-L-glutaminyl-L-methionyl-glycyl-L-alanyl-L-threonyl-L-alanyl-L-isoleucyl-L-lysyl-L-glutaminyl-L-valyl-L-lysyl-L-lysyl-L-leucyl-L-phenylalanyl-L-lysyl-L-lysyl-L-tryptophyl-glycyl-L-tryptophan. Grades: ≥96%. CAS No. 131463-18-8. Molecular formula: C128H200N32O29S. Mole weight: 2683.22. | |
| Plantaricin C19 | Plantaricin C19 is an antimicrobial peptide and an anti-Listeria bacteriocin found in Lactobacillus plantarum C19, and has antibacterial activity. Grades: >98%. CAS No. 153858-63-0. | |
| Plantaricin EF | Plantaricin EF is an antimicrobial peptide found in Lactobacillus plantarum C11, and has antibacterial activity. Alternative Names: Phe-Asn-Arg-Gly-Gly-Tyr-Asn-Phe-Gly-Lys-Ser-Val-Arg-His-Val-Val-Asp-Ala-Ile-Gly-Ser-Val-Ala-Gly-Ile-Leu-Lys-Ser-Ile-Arg. Grades: ≥96%. CAS No. 209623-63-2. Molecular formula: C144H233N45O39. Mole weight: 3218.72. | |
| Plantaricin JK | Plantaricin JK is an antimicrobial peptide found in Lactobacillus plantarum C1, and has antimicrobial activity. Alternative Names: Gly-Ala-Trp-Lys-Asn-Phe-Trp-Ser-Ser-Leu-Arg-Lys-Gly-Phe-Tyr-Asp-Gly-Glu-Ala-Gly-Arg-Ala-Ile-Arg-Arg. Grades: ≥95%. CAS No. 209623-64-3. Molecular formula: C133H198N42O34. Mole weight: 2929.31. | |
| Plantaricin NC8 | Plantaricin NC8 is an antimicrobial peptide found in Lactobacillus plantarum NC8, and has antimicrobial activity. Alternative Names: Leu-Thr-Thr-Lys-Leu-Trp-Ser-Ser-Trp-Gly-Tyr-Tyr-Leu-Gly-Lys-Lys-Ala-Arg-Trp-Asn-Leu-Lys-His-Pro-Tyr-Val-Gln-Phe. Grades: ≥95%. CAS No. 515130-54-8. Molecular formula: C169H244N42O38. Mole weight: 3472.07. | |
| Plantaricin S | Plantaricin S is an antimicrobial peptide found in Lactobacillus plantarum LPCO10, and has antibacterial activity. Alternative Names: Asn-Lys-Leu-Ala-Tyr-Asn-Met-Gly-His-Tyr-Ala-Gly-Lys-Ala-Thr-Ile-Phe-Gly-Leu-Ala-Ala-Trp-Ala-Leu-Leu-Ala. Grades: ≥97%. CAS No. 148937-56-8. | |
| Plantaricin W | Plantaricin W is an antimicrobial peptide found in Lactobacillus plantarum (Lactiplantibacillus plantarum), and has antibacterial activity. Alternative Names: Plantaricin W (Lactobacillus plantarum strain LMG 2379 β precursor) (9Cl); GenBank AAG02566; Plw. Grades: >98%. CAS No. 341521-94-6. Molecular formula: C299H507N93O95S5. Mole weight: 7085.10. | |
| Platycodin D | Platycodin D is a triterpenoid saponin. Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases. Platycodin D and D3 increased mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization. Uses: Hypolipidemic. Alternative Names: Platycodin; Platycodin D ,98%; Platycodin D Exclusive. Grades: >98%. CAS No. 58479-68-8. Molecular formula: C57H92O28. Mole weight: 1225.33. | |
| Plectasin | Plectasin is an antibiotic protein from the mushroom Pseudoplectania nigrella. It belongs to the antimicrobial peptide class called fungal defensins. It has antibacterial activity. Grades: >98%. CAS No. 676464-91-8. Molecular formula: C189H273N53O56S7. Mole weight: 4407.99. | |
| Plitidepsin | Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Alternative Names: aplidin; aplidine; plitidepsin; dehydrodidemnin B. Grades: >98%. CAS No. 137219-37-5. Molecular formula: C57H87N7O15. Mole weight: 1110.34. | |
| (+)-p-Menth-2-ene-1, 8-diol | (+)-p-Menth-2-ene-1, 8-diol. Uses: Intermediate in the preparation of ?9-tetrahydro cannabinol. Alternative Names: (+)-p-Menth-2-ene-1, 8-diol; (1R,4R)-2-Menthene-1,8-diol. Grades: 95%. CAS No. 20053-40-1. Molecular formula: C10H18O2. | |
| PMSF | Used as a Protease inhibitor such as Chymotrypsin, Trypsin and Thrombin as well as Acetylcholineesterase. Alternative Names: Phenylmethylsulfonyl Fluoride. Grades: ≥ 99% (GC). CAS No. 329-98-6. Molecular formula: C7H7FO2S. Mole weight: 174.19. | |
| PMX 205 | PMX 205 is a potent C5a receptor peptide antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Alternative Names: PMX-205; Hydrocinnamate. Grades: >98%. CAS No. 514814-49-4. Molecular formula: C45H62N10O6. Mole weight: 839.05. | |
| Pneumocandin A0 | Pneumocandin A0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Pneumocandin A0 is an impurity of Micafungin. Alternative Names: 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine, cyclic peptide deriv.; Antibiotic L 671329; L 671329; Stereoisomer of N2-(10,12-dimethyl-1-oxotetradecyl)-4,5-dihydroxy-L-ornithyl-L-threonyl-4-hydroxy-L-prolyl-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-proline cyclic (6→1)-peptide. Grades: 95%. CAS No. 120692-19-5. Molecular formula: C51H82N8O17. Mole weight: 1079.24. | |
| Pneumocandin C0 | Pneumocandin C0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Pneumocandin C0 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Alternative Names: Pneumocandin B0, 6-(trans-4-hydroxy-L-proline)-; Pneumocandin B0, 6-((4R)-4-hydroxy-L-proline)-; 6-[(4R)-4-Hydroxy-L-proline]pneumocandin B0. Grades: ≥95%. CAS No. 144074-96-4. Molecular formula: C50H80N8O17. Mole weight: 1065.21. | |
| PNU-159682 | PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. It is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity, and shows >3,000-fold cytotoxic than its parent compound (MMDX and doxorubicin). It is a more potent and well tolerated ADC cytotoxin than doxorubicin. Uses: Adcs cytotoxin. Alternative Names: (8S,10S)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano(4',3':4,5)oxazolo(2,3-c)(1,4)oxazin-3-yl)oxy)-5,12-naphthacenedione; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano(4',3':4,5)oxazolo(2,3-c)(1,4)oxazin-3-yl)oxy)-, (8S,10S)-; PNU159682; PNU 159682. Grades: ≥97%. CAS No. 202350-68-3. Molecular formula: C32H35NO13. Mole weight: 641.62. | |
| PNU159682-EDA-Gly3 | PNU159682-EDA-Gly3 is a drug-linker conjugate for ADC by using PNU159682 (a potent DNA topoisomerase II inhibitor), linked via EDA-Gly3. Alternative Names: PNU-159682-EDA-Gly3. Molecular formula: C39H48N6O15. Mole weight: 840.84. | |
| Podophyllotoxin | Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. It is a potent inhibitor of microtubule assembly and DNA topoisomerase II and it is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. Uses: Antiviral (topical). Alternative Names: Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9R)-; (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5α,5aβ,8aα,9α)]-; (-)-Podophyllotoxin; Condyline; Condylox; NSC 24818; Podofilox. Grades: >98%. CAS No. 518-28-5. Molecular formula: C22H22O8. Mole weight: 414.41. | |
| Pogostone | Pogostone, isolated from the herbs of Pogostemon cablin (Blanco) Benth, possesses potent anti-bacterial and anti-fungal activities and has been used for the quality control of essential oil of Pogostemon cablin. It could inhibit both gram negative bacteria (0.098-1 600 μg/ml) and gram positive bacteria (0.098-800 μg/ml). Besides, Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. Pogostone exhibited an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. Uses: Anti-bacterial / anti-fungal. Alternative Names: Dhelwangin; 4-Hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one. Grades: >98%. CAS No. 23800-56-8. Molecular formula: C12H16O4. Mole weight: 224.26. | |
| Polyalthic acid | Polyalthic acid is a naturally occurring diterpene found in copaiba oil and is reported to have anti-tumor activity. CAS No. 1235-76-3. Molecular formula: C20H28O3. Mole weight: 316.43. | |
| Polyamideamine epichlorohydrin resin | Polyamideamine epichlorohydrin resin is a crosslinked heteropolymer with cationic charges, which is widely used as a wet strength agent in the paper-making process. Alternative Names: polyamideamine-epichlorohydrin (PAE) resin; PAE resin. | |
| Polyaniline (emeraldine salt) long chain, grafted to lignin | Polyaniline (emeraldine salt) long chain, grafted to lignin. CAS No. 335349-50-3. | |
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