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Hydroxyurea
Hydroxyurea is used as an inhibitor of DNA synthesis. As an anti-neoplastic, hydroxyurea inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide. Group: Biochemicals. Alternative Names: Carbamohydroxamic acid; N-Carbamoyl hydroxylamine; N-Hydroxyurea; Biosupressin; Carbamohydroxamic Acid; Carbamoyl Oxime; Cytodrox; Droxia; HU; Hidrix; Hydrea; Hydreia; Hydroxycarbamide; Hydroxycarbamine; N- (Aminocarbonyl) hydroxylamine; Hydroxylurea; Hydura; Hydurea; Litaler; Litalir; N-Carbamoyl hydroxylamine; NCI C04831; NSC 32065; Oxyurea; SK 22591; SQ 1089. Grades: Molecular Biology Grade. CAS No. 127-07-1. Pack Sizes: 10g, 25g, 100g, 250g, 500g. Molecular Formula: CH4N2O2, Molecular Weight: 76.06. US Biological Life Sciences.
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Hydroxy Urea-13C,15N2
Labeled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide. Group: Biochemicals. Alternative Names: N-Hydroxyurea-13C,15N2; Biosupressin-13C,15N2; Carbamohydroxamic Acid-13C,15N2; Carbamoyl Oxime-13C,15N2; Cytodrox-13C,15N2; Droxia-13C,15N2; Hydrea-13C,15N2; Hydreia-13C,15N2; Hydroxycarbamide-13C,15N2; Hydroxycarbamine-13C,15N2; N- (Aminocarbonyl) hydroxylamine-13C, 15N2; Hydroxylurea-13C,15N2; Hydura-13C,15N2; Litaler-13C,15N2; N-Carbamoylhydroxylamine-13C,15N2; NSC 32065-13C,15N2; Oxyurea-13C,15N2; SK 22591-13C,15N2; SQ 1089-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Hydroxy vandetanib
Hydroxy vandetanib. Group: Biochemicals. Alternative Names: 4- [ [ [4- [ (4-Bromo-2-fluorophenyl) amino] -6-methoxy-7-quinazolinyl] oxy] methyl] -1-piperidinemethanol. Grades: Highly Purified. CAS No. 910298-61-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H24BrFN4O3. US Biological Life Sciences.
A metabolite of Varenicline. Group: Biochemicals. Alternative Names: 1,6,7,8,9,10-Hexahydro-6,10-methano-2H-pyrazino[2,3-h][3]benzazepin-2-one. Grades: Highly Purified. CAS No. 357424-21-6. Pack Sizes: 1mg. US Biological Life Sciences.
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Hydroxy Varenicline N-Trifluoroacetate
Protected Varenicline metabolite. Group: Biochemicals. Alternative Names: 1,6,7,8,9,10-Hexahydro-8-(trifluoroacetyl)-6,10-methano-2H-pyrazino[2,3-h][3]benzazepin-2-one. Grades: Highly Purified. CAS No. 357426-10-9. Pack Sizes: 5mg. US Biological Life Sciences.
Hydroxyzine dihydrochloride. Group: Biochemicals. Alternative Names: 2- [2- [4- [ (4-Chlorophenyl) -phenylmethyl] -1-piperazinyl] ethoxy] ethanol dihydrochloride; Alamon; Atarax. Grades: Highly Purified. CAS No. 2192-20-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C21H29Cl3N2O2. US Biological Life Sciences.
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Hygromycin B 50mg/ml Solution
Hygromycin B is an aminoglycosidic antibiotic which inhibits protein synthesis in bacteria, fungi and mammalian cells and is used to select prokaryotic and eukaryotic cells that have been transfected with the Hygromycin gene (hyg, hph, HMA, HM+). Group: Biochemicals. Alternative Names: Streptomyces hygroscopicus. Grades: Molecular Biology Grade. CAS No. 31282-04-9. Pack Sizes: 1ml, 5x1ml, 10x1ml. US Biological Life Sciences.
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Hygromycin B, Streptomyces hygroscopicus (Powder)
Hygromycin B is an aminoglycosidic antibiotic which inhibits protein synthesis in bacteria, fungi and mammalian cells and is used to select prokaryotic and eukaryotic cells that have been transfected with the Hygromycin gene (hyg, hph, HMA, HM+). Group: Biochemicals. Alternative Names: O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1?2-3)-O- β-D-talopyranosyl-(1?5)-2-deoxy-N3-methyl-D-streptamine; Antihelmycin; Hygromix 2.4; Hygromix-8; Hygrovetin; Hygrovetine. Grades: Molecular Biology Grade. CAS No. 31282-04-9. Pack Sizes: 100KU, 500KU, 1MU. US Biological Life Sciences.
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Hymenialdisine
A potent inhibitor of a variety of kinases including MEK-1, GSK-3B, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Hymenialdisine methanoate
Hymenialdisine methanoate. Group: Biochemicals. Alternative Names: (4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7 -tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one Methanoate. Grades: Highly Purified. CAS No. 84094-94-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C12H14BrN5O3. US Biological Life Sciences.
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Hyocholic acid
Hyocholic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 547-75-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences.
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Hyodeoxycholic acid
Hyodeoxycholic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 83-49-8. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C24H40O4. US Biological Life Sciences.
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Hyodeoxycholic acid sodium salt
Hyodeoxycholic acid sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 10421-49-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C24H39NaO4. US Biological Life Sciences.
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Hyoscyamine
Hyoscyamine. Group: Biochemicals. Alternative Names: Hyoscyamine; Daturine; Duboisine. Grades: Plant Grade. CAS No. 101-31-5. Pack Sizes: 20mg. Molecular Formula: C17H23NO3, Molecular Weight: 289.369. US Biological Life Sciences.
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Hyoscyamine sulfate hydrate
Hyoscyamine sulfate hydrate. Group: Biochemicals. Grades: Plant Grade. CAS No. 620-61-1. Pack Sizes: 20mg. Molecular Formula: C34H48N2O10S, Molecular Weight: 676.82. US Biological Life Sciences.
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Hypaconitine
Hypaconitine. Group: Biochemicals. Alternative Names: (1a, 6a, 14a, 15a, 16b)1, 6, 16-Trimethoxy-4-(methoxymethyl)-20-methylaconitane-8, 13, 14, 15-tetrol 8-acetate 14-benzoate. Grades: Highly Purified. CAS No. 6900-87-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C33H45NO10. US Biological Life Sciences.
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Hypaphorine
Hypaphorine. Group: Biochemicals. Grades: Plant Grade. CAS No. 487-58-1. Pack Sizes: 20mg. Molecular Formula: C14H18N2O2, Molecular Weight: 246.31. US Biological Life Sciences.
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Hyperforin DCHA
Key constituent of St. John's wort. Shows properties of potential pharmacological interest, including anti-bacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 (sirtuin 1) and SIRT2 (sirtuin 2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 238074-03-8. Pack Sizes: 500ug, 1mg. Molecular Formula: C35H51O4 C12H24N. US Biological Life Sciences.
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Hypericin
Hypericin is an extract from Hypericum perforatum L. hypericaceae (also known as St. Johns wort) and is believed to be an antibiotic/antiviral, specifically acting as a kinase inhibitor. Group: Biochemicals. Alternative Names: 1, 3, 4, 6, 8, 13-Hexahydroxy-10, 11-dimethylphenanthro[1, 10, 9, 8-opqra]perylene-7, 14-dione; 1, 3, 4, 6, 8, 13-Hexahydroxy-10, 11-dimethylphenanthro[1, 10, 9, 8-opqra]perylene-7, 14-dione P-conformer; Cyclo-Werol; Cyclosan; Hyperflav; Hypericum red; NSC 407313. Grades: Highly Purified. CAS No. 548-04-9. Pack Sizes: 1mg, 2.5mg, 5mg, 10mg. Molecular Formula: C30H16O8, Molecular Weight: 506.46. US Biological Life Sciences.
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Hyperoside
Loss on Drying: Group: Biochemicals. Alternative Names: Quercetin 3-galactoside; Hyperin. Grades: Plant Grade. CAS No. 482-36-0. Pack Sizes: 20mg. US Biological Life Sciences.
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hypocrellin A
hypocrellin A. Group: Biochemicals. Grades: Plant Grade. CAS No. 77029-83-5. Pack Sizes: 10mg. Molecular Formula: C30H26O10, Molecular Weight: 546.52. US Biological Life Sciences.
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Hypocrellin B
Hypocrellin B. Group: Biochemicals. Grades: Plant Grade. CAS No. 123940-54-5. Pack Sizes: 10mg. Molecular Formula: C30H26O10, Molecular Weight: 546.52. US Biological Life Sciences.
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Hypocrellin C
Hypocrellin C. Group: Biochemicals. Grades: Plant Grade. CAS No. 149457-83-0. Pack Sizes: 10mg. Molecular Formula: C30H24O9, Molecular Weight: 528.51. US Biological Life Sciences.
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Hyponine D
Hyponine D. Group: Biochemicals. CAS No. 259823-31-9. Pack Sizes: 5mg. US Biological Life Sciences.
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Hyponine E
Hyponine E. Group: Biochemicals. Grades: Plant Grade. CAS No. 226975-99-1. Pack Sizes: 2mg. Molecular Formula: C45H48N2O19, Molecular Weight: 920.87. US Biological Life Sciences.
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Hypotaurine
Hypotaurine. Group: Biochemicals. Grades: Purified. CAS No. 300-84-5. Pack Sizes: 100mg. US Biological Life Sciences.
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Hypothemycin
Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Potent and selective threonine/tyrosine-specific kinase, MEK and other protein kinases inhibitor in both in vitro and in vivo studies. Group: Biochemicals. Alternative Names: 3H-Oxireno [k] [2] benzoxacyclotetradecin-5, 11 (2H, 4H) -dione, 1a, 8, 9, 15b-tetrahydro-3, 4, 12-trihydroxy-14-methoxy-9-methyl-, (1aR, 3S, 4S, 6Z, 9S, 15bR) -, NSC354462. Grades: Highly Purified. CAS No. 76958-67-3. Pack Sizes: 250ug, 1mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
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i3-Bromo-4-nitropyridine
i3-Bromo-4-nitropyridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 89364-04-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H3BrN2O2. US Biological Life Sciences.
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IAANS
IAANS, is a novel sulfhydryl-reactive probe that cna be used as a Fluorescence dye. Group: Biochemicals. Grades: Highly Purified. CAS No. 143756-46-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H14IN2NaO4S, Molecular Weight: 504.27. US Biological Life Sciences.
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Ibandronate sodium
Ibandronate sodium. Group: Biochemicals. Grades: Highly Purified. CAS No. 138844-81-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C9H22NNaO7P2. US Biological Life Sciences.
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Ibandronate sodium monohydrate
Ibandronate sodium monohydrate. Group: Biochemicals. Alternative Names: BM-21.0955; Bondronat. Grades: Highly Purified. CAS No. 138926-19-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H24NNaO8P2. US Biological Life Sciences.
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Ibandronic acid
Ibandronic acid. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; BPH 24. Grades: Highly Purified. CAS No. 114084-78-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H23NO7P2. US Biological Life Sciences.
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Ibandronic Acid-d3
Labeled Ibandronic Acid. A bisphosphonate antiresorptive agent. Bone resorption inhibitor. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; BPH 24-d3; Ibandronate-d3; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] diphosphonic Acid. Grades: Highly Purified. CAS No. 1130899-41-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
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IBC 293
IBC 293. Group: Biochemicals. Grades: Purified. CAS No. 306935-41-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Iberin
Iberin. Group: Biochemicals. Alternative Names: 1-Isothiocyanato-3-(methylsulfinyl)-propane; 3-Methylsulfinylpropyl Isothiocyanate; NSC 321801. Grades: Highly Purified. CAS No. 505-44-2. Pack Sizes: 5mg. Molecular Formula: C5H9NOS2, Molecular Weight: 163.26. US Biological Life Sciences.
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IBMX
IBMX. Group: Biochemicals. Grades: Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences.
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IBMX (3-Isobutyl-1-methylxanthine)
3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences.
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Ibotenic Acid
Ibotenic acid is a conformationally restricted analog of glutamic acid and a a potent Glu agonist.A highly potent agonist ofnMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts. Group: Biochemicals. Alternative Names: a-Amino-3-hydroxy-5-isoxazoleacetic acid;; (2-amino-2-(3-hydroxyisoxazol-5-yl) acetic acid; Glutamate Receptor Agonist; NSC 204850. Grades: Highly Purified. CAS No. 2552-55-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C?H?N?O?, Molecular Weight: 158.11. US Biological Life Sciences.
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Ibrutinib-d4
Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton s tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences.
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Ibudilast
Ibudilast. Group: Biochemicals. Grades: Purified. CAS No. 50847-11-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Ibufenac
Ibufenac. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic acid; 4- (2-Methylpropyl) phenylacetic acid; 4-Isobutoxyphenylacetic acid. Grades: Highly Purified. CAS No. 1553-60-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H16O2. US Biological Life Sciences.
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Ibuprofen
Ibuprofen. Group: Biochemicals. Alternative Names: Isobutyl propanoicphenolic acid; (RS) -2- (4- (2-Methylpropyl) phenyl) propanoic acid; Racemic ibuprofen. Grades: Highly Purified. CAS No. 15687-27-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H18O2. US Biological Life Sciences.
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Ibuprofen alcohol
Ibuprofen alcohol. Group: Biochemicals. Alternative Names: b-Methyl-4- (2-methylpropyl) benzeneethanol; 2- (4-Isobutylphenyl) propanol; 2-(4-Isobutylphenyl)propyl alcohol. Grades: Highly Purified. CAS No. 36039-36-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H20O. US Biological Life Sciences.
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Ibuprofen Carboxylic Acid-d3 (Mixture of Diastereomers)
The major labeled metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. Group: Biochemicals. Alternative Names: 4-(1-Carboxyethyl)-α-methylbenzenepropanoic Acid-d3; 2, 4- (2-Carboxypropyl) phenylpropionic Acid-d3; 2-[4- (2-Carboxypropyl) phenyl]propionic Acid-d3; Carboxyibuprofen-d3. Grades: Highly Purified. CAS No. 1216505-29-1. Pack Sizes: 1mg. US Biological Life Sciences.
The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. Group: Biochemicals. Alternative Names: 4-(1-Carboxyethyl)-a-methyl-benzenepropanoic Acid; 2, 4- (2-Carboxypropyl) phenylpropionic Acid; 2-[4- (2-Carboxypropyl) phenyl]propionic Acid; Carboxyibuprofen. Grades: Highly Purified. CAS No. 15935-54-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Ibuprofen Impurity L
Ibuprofen Impurity L. Group: Biochemicals. Grades: Highly Purified. CAS No. 53949-53-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C13H18O3. US Biological Life Sciences.
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Ibuprofen Impurity N
Ibuprofen Impurity N. Group: Biochemicals. Grades: Highly Purified. CAS No. 3585-52-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Ibuprofen Methocarbamol Ester
Ibuprofen Methocarbamol Ester is the condensation product of Ibuprofen and methocarbamol. Various studies have been done to investigate the ability of Ibuprofen Methocarbamol Ester as an both antiinflammatory and muscle relaxant. Group: Biochemicals. Alternative Names: α -Methyl-4- (2-methylpropyl) -1-[[ (aminocarbonyl) oxy]methyl]-2- (2-methoxyphenoxy) ethyl Ester Benzeneacetic Acid. Grades: Highly Purified. CAS No. 111632-17-8. Pack Sizes: 25mg. US Biological Life Sciences.
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Ibutilide Fumarate
A methanesulfonanilide antiarrhythmic agent; prologns myocardial action potential duration, predominantly by activation of slow inward sodium current. Antiarrhythmic (class III). Group: Biochemicals. Alternative Names: (+ / -) -N- [4- [4- (Ethylheptylamino) -1-hydroxybutyl] phenyl] methanesulfonamide. Grades: Highly Purified. CAS No. 122647-32-9. Pack Sizes: 10mg. US Biological Life Sciences.
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Ibutilide Fumarate-d5
Ibutilide Fumarate-d5. Group: Biochemicals. Alternative Names: (+ / -) -N- [4- [4- (Ethylheptylamino) -1-hydroxybutyl] phenyl] methanesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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ICA 069673
ICA 069673. Group: Biochemicals. Grades: Purified. CAS No. 582323-16-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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ICA 110381
ICA 110381. Group: Biochemicals. Grades: Purified. CAS No. 325457-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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ICA 121431
ICA 121431. Group: Biochemicals. Grades: Purified. CAS No. 313254-51-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Icariin
Icariin. Group: Biochemicals. Grades: Plant Grade. CAS No. 489-32-7. Pack Sizes: 20mg. Molecular Formula: C33H40O15, Molecular Weight: 676.66. US Biological Life Sciences.
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Icariside I
Icariside I. Group: Biochemicals. Grades: Plant Grade. CAS No. 56725-99-6. Pack Sizes: 10mg. Molecular Formula: C27H30O11, Molecular Weight: 530.52. US Biological Life Sciences.
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Icaritin
Icaritin. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 118525-40-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C21H20O6. US Biological Life Sciences.
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Icaritin (Anhydroicaritin)
Icaritin (Anhydroicaritin). Group: Biochemicals. Grades: Plant Grade. CAS No. 118525-40-9. Pack Sizes: 20mg. Molecular Formula: C21H20O6, Molecular Weight: 368.38. US Biological Life Sciences.
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Ichthammol
Ichthammol is an antibacterial, fungicidal, antiinflammatory agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 8029-68-3. Pack Sizes: 100g, 250g. Molecular Formula: N/A, Molecular Weight: US Biological Life Sciences.
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ICI 63197
ICI 63197. Group: Biochemicals. Grades: Purified. CAS No. 27277-00-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Icilin
Icilin. Group: Biochemicals. Grades: Purified. CAS No. 36945-98-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Iclaprim
Iclaprim. Group: Biochemicals. Alternative Names: 5-[(2-Cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-2,4-pyrimidine-diamine. Grades: Highly Purified. CAS No. 192314-93-5. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C19H22N4O3. US Biological Life Sciences.
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ICMT Inhibitor (Cysmethynil)
An inhibitor of protein prenylation. Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt.A cell-permeable indole acetamide that acts as a substrate-competitive and AdoMet-noncompetitive Icmt.25uM) induces G1 cell cycle-arrest and autophagy-mediated, but not apoptotic, cell death in prostate cancer PC3 cells with concomitant PI 3-K/Akt and mTOR signaling blockage, consistent with inhibition of Icmt-mediated activation of Ras and Rheb GTPases. Murine PC3 xenograft studies reveal limited in vivo efficacy. Group: Biochemicals. Alternative Names: Cysmethynil; 2-(5-(3-Methylphenyl)-1-octyl-1H-indol-3-yl)acetamide, 2-(1-Octyl-5-m-tolyl-1H-indol-3-yl) acetamide; Isoprenylcysteine Carboxyl Methyltransferase Inhibitor). Grades: Highly Purified. CAS No. 851636-83-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C25H32N2O, Molecular Weight: 376.5. US Biological Life Sciences.
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Icomethasone
Icomethasone is a metabolite of Mometasone Furoate (M4425). Group: Biochemicals. Alternative Names: (11 β,16α)-9-Chloro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Icometasone. Grades: Highly Purified. CAS No. 4647-20-5. Pack Sizes: 10mg. Molecular Formula: C22H29ClO5, Molecular Weight: 408.92. US Biological Life Sciences.
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Icomethasone 21-Acetate
Icomethasone 21-Acetate. Group: Biochemicals. Alternative Names: Icometasone-21-acetate; 9-Chloro-11 β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione; (11 β,16α)-21-(Acetyloxy)-9-chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 24916-91-4. Pack Sizes: 10mg. US Biological Life Sciences.
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Icomethasone 21-Mesylate
Icomethasone 21-Mesylate is a derivative of Icomethasone, used in the preparation of Mometasone. Group: Biochemicals. Alternative Names: (11 β , 16α ) -9-Chloro-11, 17-dihydroxy-16-methyl-21-[ (methylsulfonyl) oxy]pregna-1, 4-diene-3, 20-dione. Grades: Highly Purified. CAS No. 352315-75-4. Pack Sizes: 10mg. Molecular Formula: C23H31ClO7S, Molecular Weight: 487.01. US Biological Life Sciences.
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iCRT 14
iCRT 14. Group: Biochemicals. Grades: Purified. CAS No. 677331-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.