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Isosorbide Dimethyl Ether
Isosorbide Dimethyl Ether. Group: Molecular Biology. Grades: Highly Purified. CAS No. 5306-85-4. Pack Sizes: 25g. Molecular Formula: C8H14O4. US Biological Life Sciences.
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Isostearyl Alcohol EX
Isostearyl Alcohol can be used as reactant/reagent for preparation of organic compounds having linear aliphatic hydrocarbon groups as precipitation accelerators and precipitation methods using them. Group: Biochemicals. Grades: Highly Purified. CAS No. 41744-75-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C18H38O, Molecular Weight: 270.49. US Biological Life Sciences.
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Isosteviol
Isosteviol. Group: Biochemicals. Alternative Names: (4a,8b,13b)-13-Methyl-16-oxo-17-norkauran-18-oic Acid. Grades: Highly Purified. CAS No. 27975-19-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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Isotachysterol 3
Isotachysterol3 is a degradation product of Vitamin D3. Isotachysterol3 has been shown to stimulat intestinal Ca transport and bone Ca mobilization in anephric rats. Group: Biochemicals. Alternative Names: (3 β,6E)-9,10-Secocholesta-5(10),6,8(14)-trien-3-ol; (E)-9,10-Secocholesta-5(10),6,8(14)-trien-3 β-ol; Toxisterol3 D3. Grades: Highly Purified. CAS No. 22350-43-2. Pack Sizes: 5mg. Molecular Formula: C27H44O, Molecular Weight: 384.64. US Biological Life Sciences.
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iso-Talipexole, Dihydrochloride
An analogue of Talipexole, an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Isothiazole
Isothiazole. Group: Biochemicals. Alternative Names: 1,2-Thiazole; 2-Azathiophene. Grades: Highly Purified. CAS No. 288-16-4. Pack Sizes: 500mg. Molecular Formula: C3H3NS, Molecular Weight: 85.13. US Biological Life Sciences.
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Isothiazole-5-carboxylic acid
Isothiazole-5-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 10271-85-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C4H3NO2S. US Biological Life Sciences.
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Isothiocyanic acid butyl ester
Isothiocyanic acid butyl ester. Group: Biochemicals. Alternative Names: Butyl Isothiocyanate. Grades: Highly Purified. CAS No. 592-82-5. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
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Isotretinoin
Isotretinoin. Group: Biochemicals. Grades: Purified. CAS No. 4759-48-2. Pack Sizes: 50mg. US Biological Life Sciences.
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Isourecumenol
Isourecumenol. Group: Biochemicals. CAS No. 24063-71-6. Pack Sizes: 5mg. US Biological Life Sciences.
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Isovaleric acid
Isovaleric acid (I917570) is a naturally occurring aroma compound found in Bartlett pear brandies, vanilla beans, rape-honey and banana. Group: Biochemicals. Grades: Highly Purified. CAS No. 503-74-2. Pack Sizes: 100g, 250 g. Molecular Formula: C5H10O2. US Biological Life Sciences.
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Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH
Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 98092-14-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
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Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH 98+%
Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences.
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Isovanillin
Isovanillin. Group: Biochemicals. Alternative Names: 3-Hydroxy-4-methoxybenzaldehyde; 3-Hydroxyanisaldehyde. Grades: Highly Purified. CAS No. 621-59-0. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. US Biological Life Sciences.
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Isovitexin
Isovitexin. Group: Biochemicals. Alternative Names: 6-Glucosylapigenin; Saponaretin; Homovitexin; Avroside. Grades: Plant Grade. CAS No. 38953-85-4. Pack Sizes: 10mg. Molecular Formula: C21H20O10, Molecular Weight: 432.377999999999. US Biological Life Sciences.
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Isoxadifen-ethyl
Isoxadifen-ethyl. Group: Biochemicals. Grades: Highly Purified. CAS No. 163520-33-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C18H17NO3. US Biological Life Sciences.
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Isoxanthohumol
Isoxanthohumol. Group: Biochemicals. Alternative Names: 2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 521-48-2,70872-29-6. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C21H22O5. US Biological Life Sciences.
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Isoxanthohumol, (2S)-
Isoxanthohumol, (2S)-. Group: Biochemicals. CAS No. 70872-29-6. Pack Sizes: 5mg. US Biological Life Sciences.
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Isoxanthopterin
Isoxanthopterin. Group: Biochemicals. Grades: Highly Purified. CAS No. 529-69-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C6H5N5O2. US Biological Life Sciences.
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Isoxazol-3-yl-methylamine hydrochloride
Isoxazol-3-yl-methylamine hydrochloride. Group: Biochemicals. Alternative Names: 3-Aminomethylisoxazole hydrochloride. Grades: Highly Purified. CAS No. 131052-58-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Isoxazol-3-yl-methylamine hydrochloride ≥95%
Isoxazol-3-yl-methylamine hydrochloride ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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Isoxazol-5-yl-methylamine hydrochloride
Isoxazol-5-yl-methylamine hydrochloride. Group: Biochemicals. Alternative Names: Isoxazol-5-ylmethanamine hydrochloride. Grades: Highly Purified. CAS No. 440099-32-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Isoxazol-5-yl-methylamine hydrochloride ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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Isoxazole-3-carbaldehyde
Isoxazole-3-carbaldehyde. Group: Biochemicals. Alternative Names: 1,2-Oxazole-3-carbaldehyde; 3-Isoxazolecarboxalde hyde. Grades: Highly Purified. CAS No. 89180-61-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Isoxazole-3-carbaldehyde 98+%
Isoxazole-3-carbaldehyde 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 89180-61-0. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
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Isoxazole-4-carboxylic acid
Isoxazole-4-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 6436-62-0. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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Isoxazole-4-carboxylic acid 98+% (HPLC)
Isoxazole-4-carboxylic acid 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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Isoxazole 99+%
Isoxazole 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 288-14-2. Pack Sizes: 5g, 25g, 100g, 1Kg. US Biological Life Sciences.
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Isoxepac
Nonsteroidal anti-inflammatory. An impurity found in olopatadine. Group: Biochemicals. Alternative Names: 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin-2-acetic Acid; Artil; 11-Oxo-6, 11-dihydrodibenz[b, e]oxepin-2-acetic Acid; NSC 300907. Grades: Highly Purified. CAS No. 55453-87-7. Pack Sizes: 1g. US Biological Life Sciences.
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Isoxsuprine Hydrochloride
A vasilodator drug. It is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. It has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that ut may be useful as a as a tocolytic agent in the treatment of preterm labour. Group: Biochemicals. Alternative Names: 4-Hydroxy-α - [1- [ (1-methyl-2-phenoxyethyl) amino] ethyl] benzenemethanol Hydrochloride; p-Hydroxy-α -[1-[ (1-methyl-2-phenoxyethyl) amino]ethyl]benzyl Alcohol Hydrochloride; p-Hydroxy-N- (1-methyl-2-phenoxyethyl) norephedrine Hydrochloride; 1- (p-Hydroxyphenyl) -2- (1'-methyl-2'-phenoxy) ethylaminopropanol-1 Hydrochloride; Dilavase; Divadilan; Duvadilan; Duviculine; Isolait; Isoxsuprine Hydrochloride; Navilox; Suprilent; Suprox SR; Tidilan; Vadosilan; Vasodilan; Vasoplex; Vasotran. Grades: Highly Purified. CAS No. 579-56-6. Pack Sizes: 1g. US Biological Life Sciences.
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Isozeaxanthin
Isozeaxanthin. Group: Biochemicals. Alternative Names: b,b-Carotene-4,4'-dio. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
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Ispinesib
Ispinesib. Group: Biochemicals. Grades: Purified. CAS No. 336113-53-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Isradipine
Isradipine. Group: Biochemicals. Grades: Purified. CAS No. 75695-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Istradefyline. Group: Biochemicals. Alternative Names: (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine,; 8-[ (1E) -2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-purine-2, 6-dione. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H24N4O4. US Biological Life Sciences.
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Istradefylline
Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinsons disease. Group: Biochemicals. Alternative Names: (E) -8-[2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-Purine-2, 6-dione; Istradefylline; KW 6002. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 1g. US Biological Life Sciences.
Istradefylline M8. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H24N4O5, Molecular Weight: 400.43. US Biological Life Sciences.
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Istradefylline M8-d3,13C
Istradefylline M8-d3,13C. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1913CH21D3N4O5, Molecular Weight: 404.44. US Biological Life Sciences.
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ISX 9
ISX 9. Group: Biochemicals. Grades: Purified. CAS No. 832115-62-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IT1t dihydrochloride
IT1t dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1092776-63-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Itaconic acid
Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. Group: Biochemicals. Alternative Names: 2-Methylenebutanedioic Acid; Methylenesuccinic Acid; 2-Methylenebutanedioic Acid; 2-Methylenesuccinic Acid; 2-Propene-1,2-dicarboxylic Acid; 4-Hydroxy-2-methylene-4-oxobutanoic Acid; Methylenebutanedioic Acid; NSC 3357; Propylenedicarboxylic Acid. Grades: Highly Purified. CAS No. 97-65-4. Pack Sizes: 1g, 5g. Molecular Formula: C?H?O?. US Biological Life Sciences.
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Itaconic anhydride
Itaconic anhydride. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-methylene-2,5-furandione; Methylenesuccinic anhydride. Grades: Highly Purified. CAS No. 2170-3-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C5H4O3. US Biological Life Sciences.
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ITD 1
ITD 1. Group: Biochemicals. Grades: Purified. CAS No. 1099644-42-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Itopride hydrochloride
Itopride hydrochloride. Group: Biochemicals. Alternative Names: N-[[4-[2- (Dimethylamino) ethoxy]phenyl]methyl]-3, 4-dimethoxy benzamide hydrochloride; HSR-803; HC-803. Grades: Highly Purified. CAS No. 122892-31-3. Pack Sizes: 1kg, 2kg, 5kg, 10kg, 25kg. Molecular Formula: C20H27ClN2O4. US Biological Life Sciences.
Dopamine D2-receptor antagonist with anticholinesterase activity. Gastroprokinetic. Group: Biochemicals. Alternative Names: N-[[4-[2- (Dimethylamino) ethoxy]phenyl]methyl]-3, 4-dimethoxy Benzamide Hydrochloride; HSR-803; HC-803; Itax; Ganaton. Grades: Highly Purified. CAS No. 122892-31-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Itopride N-Oxide
A metabolite of Itopride. Group: Biochemicals. Alternative Names: N-[[4-[2- (Dimethyloxidoamino) ethoxy]phenyl]methyl]-3, 4-dimethoxybenzamide. Grades: Highly Purified. CAS No. 141996-98-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Itraconazole-d5
An isotopically labeled, orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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ITX 3
ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IU1
IU1. Group: Biochemicals. Grades: Purified. CAS No. 314245-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Ivabradine-d3 Hydrochloride
Labeled Ivabradine. Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3-[3-[[[(7S)-3, 4-Dimethoxybicyclo[4. 2. 0]octa-1, 3, 5-trien-7-yl]methyl]methylamino-d3]propyl]-1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. Grades: Highly Purified. CAS No. 1217809-61-4. Pack Sizes: 1mg. US Biological Life Sciences.
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Ivabradine Hydrochloride
Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7S) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: Highly Purified. CAS No. 148849-67-6. Pack Sizes: 10mg. US Biological Life Sciences.
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Ivacaftor
Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences.
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Ivacaftor-d18
Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences.
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Ivacaftor N-Glucuronide
Ivacaftor N-Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C30H36N2O9, Molecular Weight: 568.61. US Biological Life Sciences.
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Ivermectin
Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin. Grades: Highly Purified. CAS No. 70288-86-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
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Ivermectin B1a
Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences.
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Ivermectin B1a-D2
Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C48H72D2O14, Molecular Weight: 877.11. US Biological Life Sciences.
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Ivermectin B1 Aglycon
Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 73162-95-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C34H50O8. US Biological Life Sciences.
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Ivermectin B1b
Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences.
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Ivermectin B1 Monosaccharide
Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 71837-27-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C41H62O11. US Biological Life Sciences.
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Ivermectin-d2
Isotope labelled Ivermectin, is the labeled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Ivermectin B1a is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study. Group: Biochemicals. Alternative Names: Ivermectin, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a. Grades: Highly Purified. CAS No. 70161-11-4. Pack Sizes: 1mg. US Biological Life Sciences.
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IWP 12
IWP 12. Group: Biochemicals. Grades: Purified. CAS No. 688353-45-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IWP 2
IWP 2. Group: Biochemicals. Grades: Purified. CAS No. 686770-61-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IWP-2
IWP-2. Group: Biochemicals. Alternative Names: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide. Grades: Highly Purified. CAS No. 686770-61-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C22H18N4O2S3. US Biological Life Sciences.
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IWP 4
IWP 4. Group: Biochemicals. Grades: Purified. CAS No. 686772-17-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IWP L6
IWP L6. Group: Biochemicals. Grades: Purified. CAS No. 1427782-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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IWR-1 (IWR-1-endo)
Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3 &beta. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3 &beta. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay). Group: Biochemicals. Alternative Names: 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: Highly Purified. CAS No. 1127442-82-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 409.4. US Biological Life Sciences.
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J 104129 Fumarate
Potent M3 muscarinic receptor antagonist that displays ~ 120-fold selectivity over M2 receptors (Ki values are 4.2, 19 and 490nM for human M3, M1 and M2 receptors respectively). Exhibits >250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (KB values are 3.3 and 170 nM for rat trachea M3 and rat right atria M2 receptors respectively). Group: Biochemicals. Alternative Names: (α R) -α -Cyclopentyl-α -hydroxy-N- [1- (4-methyl-3-pentenyl) -4-piperidinyl] benzeneacetamide Fumarate; (α R) -α -Cyclopentyl-α -hydroxy-N- [1- (4-methyl-3-pentenyl) -4-piperidinyl] benzeneacetamide (2E)-2-Butenedioate (1:1) (salt) (9CI). Grades: Highly Purified. CAS No. 257603-40-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?; (C?H?O?), Molecular Weight: 500.63. US Biological Life Sciences.