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10,11-Dehydrocurvularin
It is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including curvularia, penicillium and alternaria. It inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in alternaria alternata. Alternative Names: (4R,8E)-4,5,6,7-Tetrahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10(1H)-dione; (+)-(10E,15R)-10,11-Dehydrocurvularin; ent-Dehydrocurvularin; (R)-10,11-Dehydrocurvularin; 4,5-[[(7R)-1-Oxo-2-octene-1,7-diyl]oxy(1-oxoethane-1,2-diyl)]benzene-1,3-diol. Grades: >98% by HPLC. CAS No. 1095588-70-7. Molecular formula: C16H18O5. Mole weight: 290.31.
10,11-Dihydro-24-hydroxyaflavinine
10,11-Dihydro-24-hydroxyaflavinine is a metabolite of Aspergillus flavus. It shows insecticidal properties. Alternative Names: 1H-Benzo[d]naphthalene-3-methanol, dodecahydro-10-hydroxy-4-(1H-indol-2-yl)-α,α,5,7a,8-pentamethyl-, (3α,4β,4aα,5β,7aβ,8β,10β,11aS*)-; 10,23,24,25-Tetrahydro-24-hydroxyaflavinine. Grades: 98.0%. CAS No. 171569-81-6. Molecular formula: C28H41NO2. Mole weight: 423.63.
10,11-dihydropicromycin
10,11-dihydropicromycin is produced by the strain of Streptomyces venezuelae. It has anti-gram-positive bacterial activity. Alternative Names: Dihydropicromycin; Picromycin, 10,11-dihydro-; 14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradecan-6-yl 3,4,6-trideoxy-3-(dimethylamino)hexopyranoside. CAS No. 27656-56-0. Molecular formula: C28H49NO8. Mole weight: 527.69.
10-Decarbamoyloxy-9-dehydromitomycin B
10-Decarbamoyloxy-9-dehydromitomycin B is a mitane antibiotic produced by Streptomyces caespitosus KY 2072. It has anti-Gram-positive bacteria and anti-tumor cell activity. Alternative Names: Mitomycin H; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxy-8-methylene-, (1aS-(1a-alpha,8a-alpha,8b-alpha))-. CAS No. 74148-44-0. Molecular formula: C15H16N2O4. Mole weight: 288.30.
10-Decarbomethoxyaclacinomycin A
10-Decarbomethoxyaclacinomycin A is an anthracycline antibiotic produced by Streptomyces galilaeus MA144-Mlt mutant strain KE303. It has anti-tumor and gram-positive bacteria activity. Alternative Names: 7-epi-10-Decarbomethoxyaclacinomycin A. CAS No. 76264-91-0. Molecular formula: C40H51NO13. Mole weight: 753.83.
10-Deoxymethymycin
It is produced by the strain of Streptomyces venezuelae. 10-Deoxymethymycin is a biochemical. Alternative Names: Antibiotic YC 17; YC-17. Grades: >98%. CAS No. 11091-33-1. Molecular formula: C25H43NO6. Mole weight: 453.61.
10'-Desmethoxystreptonigrin
It is a close analogue of streptonigrin produced by selected streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. It has potent and broad spectrum antibacterial and antitumour activity. Alternative Names: 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3-methoxyphenyl)-3-methyl-; 10-Desmethoxystreptonigrin. Grades: >95% by HPLC. CAS No. 136803-89-9. Molecular formula: C24H20N4O7. Mole weight: 476.44.
10-Dihydrosteffimycin A
It is produced by the strain of Actinoplanes utahensis. 10-Dihydrosteffimycin A has anti-gram-positive bacterial activity. Alternative Names: 3,4,10,12-tetrahydroxy-2,8-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 6-deoxy-2-O-methylhexopyranoside. CAS No. 75086-96-3. Molecular formula: C28H32O13. Mole weight: 576.54.
10-Dihydrosteffimycin B
It is produced by the strain of Chaetomium sp. BB 427. 10-Dihydrosteffimycin B has anti-gram-positive bacterial activity. Alternative Names: 3,4,10,12-Tetrahydroxy-2,8-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 6-deoxy-2,4-di-O-methylhexopyranoside. CAS No. 75086-97-4. Molecular formula: C29H34O13. Mole weight: 590.57.
10-Hydroxyundeca-2,4,6,8-tetraynamide
10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic produced by Mycena viridimarginata 7638. It has anti-gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity. Alternative Names: 10-Hydroxy-undeca-2,4,6,8-tetraynamide. CAS No. 83475-37-0. Molecular formula: C11H7NO2. Mole weight: 185.18.
10-Norparvulenone
It is originally isolated from Microsphaeropsis sp. FO-5050. 10-Norparvulenone inhibits viral Sialidase by IC50 of 21 μg/mL and inhibits influenza virus A/PR/8/34 replication in MDCK cells. Alternative Names: MLS004711975; 3,4-dihydro-4,8-dihydroxy-7-(hydroxymethyl)-6-methoxy-1(2H)-naphthalenone. CAS No. 618104-32-8. Molecular formula: C12H14O5. Mole weight: 238.24.
11-Deacetoxywortmannin
11-Deacetoxywortmannin is an antibiotic produced by Aspergillus janus NRRL 3807 and Penicillum funiculosum NRRL 3363. It has a strong anti-fungal and anti-inflammatory effect, and has an anti-edema effect. Alternative Names: 11-Desacetoxywortmannin. CAS No. 31652-69-4. Molecular formula: C21H22O6. Mole weight: 370.39.
11-Demethyltomaymycin
11-Demethyltomaymycin is an antibiotic produced by Streptomyces achromogenes var. tomayrnyceticus. Antiviral. Alternative Names: 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 2-ethylidene-1,2,3,10,11,11a-hexahydro-8,11-dihydroxy-7-methoxy-. CAS No. 55511-85-8. Molecular formula: C15H18N2O4. Mole weight: 290.31.
11-Deoxy-13-deoxodaunorubicin
11-Deoxy-13-deoxodaunorubicin is an anthracycline antibiotic produced by Micromonospora peucetica B211 F.I. It has anti-gram-positive bacteria, negative bacteria and tumor activity. CAS No. 71800-92-5. Molecular formula: C27H31NO8. Mole weight: 497.54.
11-Deoxy-13-dihydrodaunorubicin
11-Deoxy-13-dihydrodaunorubicin is an anthracycline antibiotic produced by Microjnonospora peucetica B211 F. I. It has anti-gram-positive bacteria, negative bacteria and tumor activity. CAS No. 71800-90-3. Molecular formula: C27H31NO9. Mole weight: 513.54.
11-Deoxydoxorubicin
11-Deoxydoxorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Alternative Names: 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-8,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-; (1S,3S)-3-Glycoloyl-3,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; (8S-cis)-10-((3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-8,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 11-Deoxyadriamycin. Grades: ≥95%. CAS No. 71800-89-0. Molecular formula: C27H29NO10. Mole weight: 527.52.
11-Hydroxynovobiocin
11-Hydroxynovobiocin is a novobiocin homolog produced by Sebekia benihana UC 5762 (NRRL 11111). It has anti-gram-negative bacteria effect, and its activity is equivalent to 30% of novobiocin. Molecular formula: C31H36N2O12. Mole weight: 628.62.
11-Keto-9(E),12(E)-octadecadienoic acid
11-Keto-9(E),12(E)-octadecadienoic acid is originally isolated from Trichoderma sp. F5594. It can enhance the fibrinolytic activity of endothelial cells. Molecular formula: C18H30O3. Mole weight: 294.43.
11-O-Methylpseurotin A
11-O-Methylpseurotin A is a fungal metabolite originally isolated from Sporothrix sp. It decreases survival of hof1δ mutant strains of S. cerevisiae. Alternative Names: (5S,8S,9R)-8-Benzoyl-9-hydroxy-2-[(1S,2S,3Z)-1-hydroxy-2-methoxy-3-hexen-1-yl]-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione. Grades: ≥98%. CAS No. 956904-34-0. Molecular formula: C23H27NO8. Mole weight: 445.46.
1,2,3,4,5,6-hexahydro-α,1,5,5-tetramethyl-γ-oxo-3a,6-Ethano-3aH-indene-4-pentanoic acid. Alternative Names: 3a,6-Ethano-3aH-indene-4-pentanoic acid, 1,2,3,4,5,6-hexahydro-alpha,1,5,5-tetramethyl-gamma-oxo-; 3a,6-Ethano-3aH-indene-4-pentanoic acid, 1,2,3,4,5,6-hexahydro-α,1,5,5-tetramethyl-γ-oxo-. CAS No. 99524-02-4. Molecular formula: C20H30O3. Mole weight: 318.45.
1,2,4-Trihydroxybenzene
1,2,4-Trihydroxybenzene, a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes. It is a common intermediate in the biodegradation of many aromatic compounds. Alternative Names: 1,2,4-Trihydroxybenzene; 2,5-Dihydroxyphenol; 2-Hydroxy-1,4-hydroquinone; 2-Hydroxy-p-benzohydroquinone; 2-Hydroxyhydroquinone; 4-Hydroxycatechol; HHQ; Hydroxyhydroquinone; NSC 2818. Grades: ≥98%. CAS No. 533-73-3. Molecular formula: C6H6O3. Mole weight: 126.11.
12-Hydroxy-6-epi-albrassitriol
12-Hydroxy-6-epi-albrassitriol is produced from cultures of Aspergillus sp. Alternative Names: 6-epi-12-Hydroxyalbrassitriol; 1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-1,4-dihydroxy-5,5,8a-trimethyl-, [1S-(1α,4β,4aα,8aβ)]-; 1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-1,4-dihydroxy-5,5,8a-trimethyl-, (1S,4R,4aS,8aS)-. Grades: 98.0%. CAS No. 178330-78-4. Molecular formula: C15H26O4. Mole weight: 270.36.
1-(3,4-Dichlorophenyl)-3-(thiazol-2-yl)thiourea
It is a thiourea derivative synthesized from 1,3-thiazole. It inhibits biofilm formation in wild type and methicillin-resistant strains of staphylococcus epidermidis. Alternative Names: 1-(3,4-Dichlorophenyl)-3-(2-thiazolyl)thiourea. Grades: ≥95%. Molecular formula: C10H7Cl2N3S2. Mole weight: 304.22.
1,3,6-Tri-O-methylarthothelin
4,5-Dichloro-6-O-Methylnorlichexanthone is a xanthone compound derived from Australian lichen. Molecular formula: C17H13Cl3O5. Mole weight: 403.6.
It is a halogen-containing thiourea derivative synthesized from 1,3-thiazole. It inhibits biofilm formation in wild type and methicillin-resistant strains of staphylococcus epidermidis. Alternative Names: 1-(3-Chloro-4-fluorophenyl)-3-(2-thiazolyl)thiourea. Grades: ≥95%. Molecular formula: C10H7ClFN3S2. Mole weight: 287.76.
13-Deoxycarminomycin
13-Deoxycarminomycin, an antineoplastic agent and a bacterial metabolite, is a cytotoxic anthracycline antibiotic produced by Streptomyces peucetius var. carminatus (a biochemical mutant of Streptomyces peucetius var. caesius). It has activity against Gram-positive bacteria, Gram-negative bacteria, tumors and P-388 murine leukemia. Alternative Names: Antibiotic D 788-11; R 20X; 13-Deoxocarminomycin; (8S)-10α-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8α,11-tetrahydroxy-5,12-naphthacenedione; 13-Deoxocarminomycin I; (1S,3S)-3-Ethyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-8-ethyl-1,6,8,11-tetrahydroxy-, (8S-cis)-; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)-. Grades: ≥95%. CAS No. 76034-18-9. Molecular formula: C26H29NO9. Mole weight: 499.51.
1,3-Diphenethylurea
N,N'-Diphenylethylurea is a phenylalanine metabolite isolated from marine Streptomyces. Alternative Names: N,N'-bis(2-phenylethyl)urea; N,N'-Diphenethylurea; N,N'-Bis(phenethyl)urea; N-(2-phenylethyl)[(2-phenylethyl)amino]carboxamide; Glimepiride Impurity 40. Grades: ≥ 95 %. CAS No. 5467-84-5. Molecular formula: C17H20N2O. Mole weight: 268.35.
13-Hydroxyglucopiericidin A
13-Hydroxyglucopiericidin A is an antibiotic produced by Streptomyces sp. OM-5689. It has strong anti-tumor cell activity. CAS No. 132150-13-1. Molecular formula: C31H47NO10. Mole weight: 593.70.
13-labdene-8α,15-diol
13-labdene-8α,15-diol. Alternative Names: rel-(1R,2R,4aS,8aS)-1-((E)-5-hydroxy-3-methylpent-3-en-1-yl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol. CAS No. 100349-53-9. Molecular formula: C20H36O2. Mole weight: 308.5.
14α-Hydroxypaspalinine
14α-Hydroxypaspalinine is a secondary metabolite of indole isolated from Aspergillus niger. 14-α-hydroxypaspalinine is a member of the paspalinine-causing toxin family and is usually related to the toxicity of animals to pasture. Alternative Names: Hydroxypaspalinine, 14-alpha-. Grades: >95% by HPLC. CAS No. 151341-77-4. Molecular formula: C27H31NO5. Mole weight: 449.54.
14-Norpseurotin A
14-Norpseurotin A is a natural compound isolated from the cultures of Aspergillus fumigatus. Alternative Names: 1-Oxa-7-azaspiro[4.4]non-2-ene-4,6-dione, 8-benzoyl-2-[(1S,2S,3Z)-1,2-dihydroxy-3-penten-1-yl]-9-hydroxy-8-methoxy-3-methyl-, (5S,8S,9R)-. Grades: ≥98%. CAS No. 1031727-34-0. Molecular formula: C21H23NO8. Mole weight: 417.41.
14-O-Acetylindolactam V
14-O-Acetylindolactam V is an antibiotic isolated from the Actinomyces NA34-17. 14-O-Acetylindolactam V has the effect of inducing early Epstein-Barr virus antigen. Alternative Names: 2S)-1-Methyl-5alpha-(acetoxymethyl)-2beta-isopropyl-1,2,4,5,6,8-hexahydro-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonine-3-one; [(2S,5S)-1-methyl-3-oxo-2-(propan-2-yl)-2,3,4,5,6,8-hexahydro-1H-[1,4]diazonino[7,6,5-cd]indol-5-yl]methyl acetate. CAS No. 91403-61-1. Molecular formula: C19H25N3O3. Mole weight: 343.42.
14-Oxabicyclo[11.2.1]hexadeca-4,8-diene-12-carboxylic acid, 8-formyl-4,15,15-trimethyl-, (1R,4Z,8E,12S,13S)-. Alternative Names: Oxabicyclo[11.2.1]hexadeca-4,8-diene-12-carboxylic acid, 8-formyl-4,15,15-trimethyl-, (1R,4Z,8E,12S,13S)-, 14-. CAS No. 87340-32-7. Molecular formula: C20H30O4. Mole weight: 334.45.
1-[(4R,5R)-4,5-dihydroxy-L-ornithine]-Echinocandin B
1-[(4R,5R)-4,5-dihydroxy-L-ornithine]-Echinocandin B is an intermediate of Anidulafungin, an echinocandin antifungal drug. Alternative Names: Echinocandin B nucleus; (2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-9-Amino-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methylhexadecahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosine-5,8,14,19,22,25(9H,25aH)-hexone; Echinocandin B, 1-[(4R,5R)-4,5-dihydroxy-L-ornithine]-. Grades: 95%. CAS No. 79411-15-7. Molecular formula: C34H51N7O15. Mole weight: 797.81.
15-Acetoxyscirpenol
15-Acetoxyscirpenol is a trichothecene mycotoxin isolated from predominantly. Alternative Names: MAS; 15-Monoacetoxyscirpenol; 15-Deacetylanguidin; 4-Deacetylanguidin; YD0111000; 15-Mono-O-acetylscirpenol; Trichothec-9-ene-3-alpha,4-beta,15-triol, 12,13-epoxy-, 15-acetate. CAS No. 2623-22-5. Molecular formula: C17H24O6. Mole weight: 324.37.
15-Acetyl-DON
15-Acetyl-DON is a mycotoxin produced by the fungi Fusarium culmorum and Fusarium graminearum. It can inhibit protein synthesis. Alternative Names: (3α,7α)-15-(Acetyloxy)-12,13-epoxy-3,7-dihydroxy-trichothec-9-en-8-one; 15-Acetylvomitoxin; 15-O-Acetyl-4-deoxynivalenol; Deoxynivalenol 15-Acetate; 15-Acetyl Deoxynivalenol; 15-Acetoxy-3alpha,7alpha-dihydroxy-12,13-epoxytrichothec-9-en-8-one; (3alpha,7alpha)-15-(acetyloxy)-12,13-epoxy-3,7-dihydroxytrichothec-9-en-8-one. Grades: ≥98%. CAS No. 88337-96-6. Molecular formula: C17H22O7. Mole weight: 338.35.
15-Deoxy-15-oxolankamycin
It is produced by the strain of Streptomyces violaceoniger. 15-Deoxy-15-oxolankamycin has a weak anti-gram-positive effect, with anti-Staphylococcus aureus activity equal to half that of Lankamycin. Molecular formula: C42H70O16. Mole weight: 830.99.
1,5-Dideoxy-1,5-imino-D-mannitol
It is produced by the strain of Streptomyces lavendulae GC-148. Alternative Names: (-)-1-Deoxynojirimycin. CAS No. 146747-37-7. Molecular formula: C6H13NO4. Mole weight: 163.17.
15-Hydroxy-epern-8(20)-en-18-saeure
15-Hydroxy-epern-8(20)-en-18-saeure. Alternative Names: 1-Naphthalenecarboxylic acid, decahydro-5-(5-hydroxy-3-methylpentyl)-1,4a-dimethyl-6-methylene-, [1S-[1α,4aβ,5β(R*),8aα]]-. CAS No. 47255-93-6. Molecular formula: C20H34O3. Mole weight: 322.48.
16,17-Dehydrorifamycin G
16,17-Dehydrorifamycin G is an antibiotic produced by Nocardia mediterranei R-21 (DSM 1415). It has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity. Molecular formula: C36H45NO12. Mole weight: 683.74.
16,17-Dihydrorifamycin S
Produced by the strain of Nocardia mediterranei T101. It has anti-gram-negative bacterial activity. CAS No. 51874-02-3. Molecular formula: C37H47NO12. Mole weight: 697.77.
16beta-Acetoxyhopane-6alpha,22-diol
16beta-Acetoxyhopane-6alpha,22-diol. Alternative Names: 16β-Acetoxyhopane-6α,22-diol. Molecular formula: C32H54O4. Mole weight: 502.77.
16βH-Kaurane-17,18-diol, diacetate
16βH-Kaurane-17,18-diol, diacetate. Alternative Names: Kaurane-17,18-diol, diacetate, 16βH-. CAS No. 106460-54-2. Molecular formula: C24H38O4. Mole weight: 390.56.
16-Deethylindanomycin
16-Deethylindanomycin is an antibiotic of the indanomycin group produced by Streptomyces setonii. It has anti-gram-positive bacteria and coccidia activity. Alternative Names: Omomycin; 2H-Pyran-2-acetic acid, tetrahydro-alpha,5-dimethyl-6-(1-ethyl-4-(2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)-, (3aR-(3a-alpha,4-alpha,5-alpha(1E(2R*(R*),5S*,6R*),3E),7a-beta))-. Grades: ≥95%. CAS No. 106803-22-9. Molecular formula: C29H39NO4. Mole weight: 465.62.
1,6-Dihydroxy-2-chlorophenazine
It is produced by the strain of Streptosporangium sp. 1656. It has weak anti-fungal and anti-yeast activity. Alternative Names: 1,6-Phenazinediol, 2-chloro-; 7-chloro-6-hydroxy-5H-phenazin-1-one; 7-chloro-6-hydroxyphenazin-1(5H)-one. Grades: >95%. CAS No. 93768-40-2. Molecular formula: C12H7N2O2Cl. Mole weight: 246.65.
1,6-Dihydroxyphenazine
It is produced by the strain of Streptomyces thioluteus M6-62a. It mainly has the antifungal effect, also has the inhibitory effect against the human type tuberculosis bacillus. Alternative Names: 1,6-Phenazinediol; 6-hydroxyphenazin-1(5h)-one; 6-hydroxy-5H-phenazin-1-one; 2,5-diMethoxylnaphthalene. Grades: ≥95%. CAS No. 69-48-7. Molecular formula: C12H8N2O2. Mole weight: 212.20.
1,6-Dimethoxy-phenazine
It is a simple phenazine produced by several species of streptomyces. It is a weakly active antibacterial metabolite with activity against Sarcina lutea and mycobacteria. Dimethoxyphenazine and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives. Alternative Names: Crystalloiodinine B. Grades: >98% by HPLC. CAS No. 13398-79-3. Molecular formula: C14H12N2O2. Mole weight: 240.26.
16-Hydroxyroridin L-2
16-Hydroxyroridin L-2 is a trichothecene group antibiotic produced by Myrothecium roridum CL-514.2. It is a mycotoxin with anti-tumor activity. CAS No. 87292-18-0. Molecular formula: C29H38O10. Mole weight: 546.60.
16-Methyloxazolomycin
16-Methyloxazolomycin is an antimicrobial and cytotoxic antibiotic produced by a Streptomyces sp. Alternative Names: 16R-Methyloxazolomycin. Molecular formula: C36H51N3O9. Mole weight: 669.80.
(±)-16-oxo-17-Norkauran-18-oic acid
(±)-16-oxo-17-Norkauran-18-oic acid. Alternative Names: 17-Norkauran-18-oic acid, 16-oxo-, (±)-; Dimethyl-8-oxotetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid, (4R,4aS,6aS,9R,11aR,11bS)-4,11b-. CAS No. 5095-30-7. Molecular formula: C19H28O3. Mole weight: 304.42.
17-AAG
17-AAG is an antibiotic with antineoplastic activity that inhibits heat shock protein 90 (HSP90). It was shown to induce apoptosis of mouse lymphoma cancer stem cells (CSCs) and human acute myeloid leukemia (AML) CSCs. Alternative Names: Tanespimycin; 17-Allylaminogeldanamycin; BAY 579352; 17-(Allylamino) Geldanamycin; 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; CP 127374; NSC 330507; Tanespimycin; 17AAG. Grades: >98%. CAS No. 75747-14-7. Molecular formula: C31H43N3O8. Mole weight: 585.69.
17-DMAG hydrochloride
17-DMAG hydrochloride (Alvespimycin hydrochloride) is the hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to Hsp90, a chaperone protein that aids in the assembly, maturation and folding of proteins. Subsequently, the function of Hsp90 is inhibited, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction. Alternative Names: 17-DMAG HCl; Alvespimycin HCl; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin Hydrochloride; 17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride; 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin Hydrochloride; 17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin Hydrochloride; Alvespimycin Hydrochloride; DMAG Hydrochloride; NSC 707545 Hydrochloride; 17-DMAG Hydrochloride. Grades: >98%. CAS No. 467214-21-7. Molecular formula: C32H48N4O8.HCl. Mole weight: 653.21.
17-Hydroxy-18-dehydroneogrifolin
17-Hydroxy-18-dehydroneogrifolin is isolated from the edible bodies of the mushroom Albatrellus confluens. Alternative Names: 1,3-Benzenediol, 4-[(2E,6E,10S)-10-hydroxy-3,7,11-trimethyl-2,6,11-dodecatrien-1-yl]-5-methyl-; (S)-17-Hydroxy-18,20-ene-neogrifolin. Grades: 96.0%. CAS No. 1630936-42-3. Molecular formula: C22H32O3. Mole weight: 344.49.
17-Norkauran-16-one, 3β,18-dihydroxy-, diacetate. Alternative Names: 3β,18-dihydroxy-17-Norkauran-16-one, diacetate. CAS No. 107423-06-3. Molecular formula: C23H34O5. Mole weight: 390.51.
17-Norkauran-18-oic acid, 16-hydroxy-, (-)-
17-Norkauran-18-oic acid, 16-hydroxy-, (-)-. Alternative Names: 17-Norkauran-18-oic acid, 16-hydroxy-, (-)- (8CI). CAS No. 16910-10-4. Molecular formula: C19H30O3. Mole weight: 306.44.
17-Norkauran-18-oic acid, 16-oxo-, (4α)-
17-Norkauran-18-oic acid, 16-oxo-, (4α)- is a substance obtained from Wemeria-Ciliolata. Alternative Names: (4α)-16-Oxo-17-norkauran-18-oic acid. CAS No. 18671-67-5. Molecular formula: C19H28O3. Mole weight: 304.42.
17-Norkauran-3-one
17-Norkauran-3-one. CAS No. 81727-33-5. Molecular formula: C19H30O. Mole weight: 274.44.
17-O-Demethylgeldanamycin is an ansa antibiotic produced by Streptomyces hygroscopicus B-434. Anti-tumor activity. Alternative Names: 17-Desmethylgeldanamycin; Des-O-methylgeldanamycin; 17-Des-O-methylgeldanamycin. CAS No. 52762-28-4. Molecular formula: C28H38N2O9. Mole weight: 546.61.
18-Norbeyeran-17-oic acid, 3-oxo-, methyl ester. Alternative Names: 3-oxo-18-Norbeyeran-17-oic acid methyl ester. CAS No. 887227-67-0. Molecular formula: C20H28O3. Mole weight: 316.43.
18-Norkaur-16-en-3-one
18-Norkaur-16-en-3-one. CAS No. 100227-34-7. Molecular formula: C19H28O. Mole weight: 272.42.
19,20-Epoxycytochalasin C
It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro and inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum. Alternative Names: (3S,3aR,4E,7S,9R,9aR,10aS,11S,11aR,14S,14aR)-11-(acetyloxy)-6,7,9,9a,10a,11,14,14a-octahydro-3,9-dihydroxy-1,2,7,9-tetramethyl-14-(phenylmethyl)-3H-oxireno[9,10]cycloundec[1,2-d]isoindole-8,12(3aH,13H)-dione. Grades: >99% by HPLC. CAS No. 189351-79-9. Molecular formula: C30H37NO7. Mole weight: 523.62.
19,20-Epoxycytochalasin D
It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum. Alternative Names: (1S,3S,3aR,4E,7S,9R,9aR,10aS,11S,11aR,14S,14aR)-11-(Acetyloxy)-3,3a,6,7,9,9a,10a,11,14,14a-decahydro-3,9-dihydroxy-1,7,9-trimethyl-2-methylene-14-(phenylmethyl)-1H-oxireno[9,10]cycloundec[1,2-d]isoindole-8,12(2H,13H)-dione; [1aS-(1aR*,2R*,2aS*,5R*,5aS*,6R*,8R*,8aS*,9E,12R*,14S*,14aS*)]-2-(Acetyloxy)-5,5a,6,7,8,8a,11,12,14,14a-decahydro-8,14-dihydroxy-6,12,14-trimethyl-7-methylene-5-(phenylmethyl)-2H-oxireno[9,10]cycloundec[1,2-d]isoindole-3,13(1aH,4H)-dione. Grades: >99% by HPLC. CAS No. 191349-10-7. Molecular formula: C30H37NO7. Mole weight: 523.62.