BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Z-Val-Ala-Asn-AMC | Z-Val-Ala-Asn-AMC is a substrate for the determination of cysteine endopeptidase required for antigen processing and has been used as a fluorescent substrate for porcine asparaginyl endopeptidase (AEP, legumain). Alternative Names: Cbz-Val-Ala-Asn-AMC; L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Z-VAN-AMC; Butanediimidic acid, 2-[[(2S)-1-hydroxy-2-[[(2S)-1-hydroxy-2-[[hydroxy(phenylmethoxy)methylene]amino]-3-methylbutylidene]amino]propylidene]amino]-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2S)-; benzyl ((S)-1-(((S)-1-(((S)-4-amino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1,4-dioxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate. Grades: ≥95%. CAS No. 245036-58-2. Molecular formula: C30H35N5O8. Mole weight: 593.64. |  |
| Z-VAL-ALA-ASP-AMC | Z-VAL-ALA-ASP-AMC. Alternative Names: Z-VAD-AMC; N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-a-asparagine. CAS No. 219137-91-4. Molecular formula: C30H34N4O9. Mole weight: 594.61. | |
| Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone | Z-VAD-FMK is an irreversible tripeptide inhibitor of all caspases, useful in studies involving enzymes. Alternative Names: Z-vad-FMK; N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide; benzyloxycarbonyl-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone. CAS No. 634911-81-2. Molecular formula: C22H30FN3O7. Mole weight: 467.49. | |
| Z-Val-Ala-OH | Z-Val-Ala-OH is a useful reagent in the preparation and biological evaluation of peptide amide conjugates of nucleosides as prodrugs that are converted to parent drugs by action of DPPIV/CD26. Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme. Alternative Names: Z-L-valyl-L-alanine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-3-Methylbutanamido)Propanoic Acid; Z Val Ala OH. Grades: ≥ 98% (HPLC). CAS No. 24787-89-1. Molecular formula: C16H22N2O5. Mole weight: 322.36. | |
| Z-Val-Arg-Pro-DL-Arg-fluoromethylketone | Z-Val-Arg-Pro-DL-Arg-fluoromethylketone, a cell-permeable and irreversible inhibitor of para-caspase MALT1, is based on the sequence of a published optimal tetrapeptide substrate for the A. thaliana metacaspase AtMC9. Alternative Names: MALT1 Inhibitor; Z-VRPR-FMK; L-Prolinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-(2-fluoroacetyl)butyl]-; Cbz-Val-Arg-Pro-DL-Arg-CH2F; N-[(Phenylmethoxy)carbonyl]-L-valyl-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-(2-fluoroacetyl)butyl]-L-prolinamide. Grades: ≥95%. CAS No. 1926163-57-6. Molecular formula: C31H49FN10O6. Mole weight: 676.79. | |
| Z-Val-Asp(OMe)-Val-Ala-DL-Asp(OMe)-fluoromethylketone | Z-Val-Asp(OMe)-Val-Ala-DL-Asp(OMe)-fluoromethylketone is a cell-permeable fluoromethylketone that specifically inhibits caspase-2 and, to a lesser extent, caspase-3 and caspase-7. Alternative Names: Z-VD(OMe)VAD(OMe)-FMK; Z-VDVA-(DL-Asp)-FMK; Methyl (5S,8S,11S,14S)-17-(fluoroacetyl)-5,11-diisopropyl-8-(2-methoxy-2-oxoethyl)-14-methyl-3,6,9,12,15-pentaoxo-1-phenyl-2-oxa-4,7,10,13,16-pentaazanonadecan-19-oate. Grades: ≥90%. CAS No. 1926163-61-2. Molecular formula: C32H46FN5O11. Mole weight: 695.73. | |
| Z-Val-Asp-Val-Ala-Asp-AFC | Z-VDVAD-AFC is a fluorogenic substrate for caspase-2 (ICH-1). Alternative Names: N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine; L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; Z-VDVAD-AFC. Grades: ≥95%. CAS No. 219138-08-6. Molecular formula: C39H45F3N6O13. Mole weight: 862.81. | |
| Z-Val-Glu-Ile-Asp-AFC | Z-Val-Glu-Ile-Asp-AFC is a fluorogenic substrate for caspase-6 (Mch2). Alternative Names: Z-VEID-AFC; N-Acetyl-Val-Glu-Ile-Asp-7-amino-4-(trifluoromethyl)coumarin; N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-glutamyl-L-isoleucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine. Grades: 95%. CAS No. 219138-06-4. Molecular formula: C38H44F3N5O12. Mole weight: 819.78. | |
| Z-Val-Ile-OH | Z-Val-Ile-OH. Alternative Names: Z-L-valyl isoleucine; (2S,3S)-2-((S)-2-(Benzyloxycarbonylamino)-3-Methylbutanamido)-3-Methylpentanoic Acid; Z Val Ile OH. Grades: ≥ 99% (TLC). CAS No. 41486-97-9. Molecular formula: C19H28N2O5. Mole weight: 364.44. | |
| Z-Val-Lys-Met 7-amido-4-methylcoumarin | Z-Val-Lys-Met 7-amido-4-methylcoumarin. Alternative Names: Fluorogenic Proteasome Substrate; Z-VKM-AMC. Grades: ≥98% (HPLC). CAS No. 141223-71-4. Molecular formula: C34H45N5O7S. Mole weight: 667.82. | |
| Z-Val-OEt | Z-Val-OEt. CAS No. 67436-18-4. Molecular formula: C15H21NO4. Mole weight: 279.3. | |
| Z-Val-Ome | Z-Val-Ome. Alternative Names: Cbz-l-valine methyl ester; benzyloxycarbonyl-l-valine methyl ester; N-(Benzyloxycarbonyl)-valine methyl ester; Methyl N-[(benzyloxy)carbonyl]-L-valinate; Z Val Ome. CAS No. 24210-19-3. Molecular formula: C14H19NO4. Mole weight: 265.30. | |
| Z-Val-Phe-OH | Z-Val-Phe-OH. Alternative Names: N-Benzyloxycarbonyl-L-valyl-L-phenylalanine; Z-L-valyl-L-phenylalanine; (S)-2-((S)-2-(benzyloxycarbonylamino)-3-methylbutanamido)-3-phenylpropanoic acid; N-(2-{[(Benzyloxy)(hydroxy)methylidene]amino}-1-hydroxy-3-methylbutylidene)phenylalanine; Z Val Phe OH. Grades: ≥ 99% (HPLC). CAS No. 19542-51-9. Molecular formula: C22H26N2O5. Mole weight: 398.46. | |
| Z-Val-Pro-OH | Z-Val-Pro-OH. Alternative Names: N-Cbz-valylproline; (S)-1-((S)-2-(benzyloxycarbonylamino)-3-methylbutanoyl)pyrrolidine-2-carboxylic acid; Z Val Pro OH. Grades: ≥ 98% (HPLC). CAS No. 53331-43-4. Molecular formula: C18H24N2O5. Mole weight: 348.4. | |
| Z-Val-Ser-OH | Z-Val-Ser-OH. Alternative Names: Z-L-valyl-L-serine; N-benzyloxycarbonyl-L-valyl-L-serine. Grades: ≥ 98%. CAS No. 72635-81-5. Molecular formula: C16H22N2O6. Mole weight: 338.36. | |
| Z-Val-Trp-OH | Z-Val-Trp-OH. Alternative Names: (S)-2-((S)-2-(benzyloxycarbonylamino)-3-methylbutanamido)-3-(1H-indol-3-yl)propanoic acid; Z Val Trp OH. Grades: ≥ 99% (TLC). CAS No. 18904-53-5. Molecular formula: C24H27N3O5. Mole weight: 437.50. | |
| Z-Val-Val-Arg-AMC | Z-Val-Val-Arg-AMC is a peptide used as a selective azadipeptide nitrile inhibitor for cathepsin K. Alternative Names: benzyl (S)-1-((S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate; Z Val Val Arg AMC. Grades: 95%. CAS No. 124485-41-2. Molecular formula: C34H45N7O7. Mole weight: 663.77. | |
| Z-Val-Val-OH | Z-Val-Val-OH. Alternative Names: Z-VAL-VAL-OH; Z-L-VALYL-L-VALINE. CAS No. 19542-54-2. Molecular formula: C18H26N2O5. Mole weight: 350.42. | |
| Z-VDVAD-FMK | Z-VDVAD-FMK is a cell-permeant and irreversible caspase-2 inhibitor and can inhibits apoptosis in various cell lines. Alternative Names: Z-VD(OMe)VAD(OMe)-FMK; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethyl ketone; benzyloxycarbonyl-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-|A-aspartyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK. Grades: ≥95%. CAS No. 210344-92-6. Molecular formula: C32H46FN5O11. Mole weight: 695.74. | |
| Z-VRPR-FMK trifluoroacetate salt | Z-VRPR-FMK trifluoroacetate salt is an irreversible and cell-permeable MALT1 inhibitor. Z-VRPR-FMK dose-dependently inhibits T cell activation-induced cleavage of Bcl-10. Z-VRPR-FMK reduces NF-κB-dependent gene expression in lymphocytes. Alternative Names: Z-Val-Arg-Pro-DL-Arg-FMK. Grades: >90%. Molecular formula: C31H49FN10O6.CF3CO2H. Mole weight: 790.81. | |
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