BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 4-hydroxybenzoyl-CoA | 4-hydroxybenzoyl-CoA is a pivotal intermediate in the biosynthetic pathway of aromatic compounds. Its indispensability in the compound sector stems from its paramount role in synthesizing diverse drugs and pharmaceuticals. Moreover, this compound intricately participates in crucial metabolic pathways and further contributes to studying certain genetic disorders and metabolic ailments. Synonyms: 4-hydroxybenzoyl coenzyme A; S- [2- [3- [ [ (2R) -4- [ [ [ (2R, 3S, 4R, 5R) -5- (6-aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3, 3-dimethylbutanoyl] amino] propanoylamino] ethyl] 4-hydroxybenzenecarbothioate. CAS No. 27718-41-8. Molecular formula: C28H40N7O18P3S. Mole weight: 887.64. |  |
| 4'-Hydroxy chalcone | 4'-Hydroxy chalcone is a chalcone metabolite with diverse biological activities. It is formed when chalcone is metabolized by the cytochrome (CYP) P450 isoform CYP1A1 or CYP2C6. 4'-Hydroxychalcone is a chalone derivative that exhibits moderate to good antiviral activity against tobacco mosaic virus (TMV). Synonyms: 2-Benzal-4'-hydroxyacetophenone; 2-Benzylidene-4'-hydroxyacetophenone; p-Cinnamoylphenol; NSC 242264; 4'-Hydroxychalcone. Grades: ≥98%. CAS No. 2657-25-2. Molecular formula: C15H12O2. Mole weight: 224.3. | |
| 4-Hydroxyquinazoline | 4-HQN is a poly(ADP-ribose) polymerase (PARP) inhibitor (IC50 = 9.5 μM). 4-HQN exhibits antianti-ischemic activity and reduces ROS production, subsequent mitochondrial and cell damage in rat heart. It also blocks NF-κB and AP-1 activation. Synonyms: 3H-quinazolin-4-one. Grades: ≥ 99 % by HPLC. CAS No. 491-36-1. Molecular formula: C8H6N2O. Mole weight: 146.15. | |
| 4-Imidazoleacetic Acid Hydrochloride | 4-Imidazoleacetic acid hydrochloride is a competitive antagonist of GABAC receptors. Synonyms: 2-(1H-imidazol-5-yl)acetic acid;hydrochloride; 2-(1H-imidazol-5-yl)acetic acid;hydrochloride. CAS No. 3251-69-2. Molecular formula: C5H7ClN2O2. Mole weight: 162.57. | |
| 4-Iodo-SAHA | 4-Iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. Synonyms: N1-hydroxy-N8-(4-iodophenyl)octanediamide. Grades: ≥98%. CAS No. 1219807-87-0. Molecular formula: C14H19IN2O3. Mole weight: 390.2. | |
| 4-Methylhistamine dihydrochloride | 4-Methylhistamine dihydrochloride is a potent, high affinity H4 receptor agonist (Ki = 7 nM) that displays > 100-fold selectivity over other human histamine receptor subtypes. Intratracheal administration of 4 methylhistamine (10 μg/animal) reduces airway resistance and inflammation and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of allergic asthma. Synonyms: 5-(2-Aminoethyl)-4-methylimidazole dihydrochloride; 5-Methyl-1H-imidazole-4-ethanamine Hydrochloride; 2-(5-Methyl-4-imidazolyl)ethylamine Dihydrochloride; 4-(2-Aminoethyl)-5-methylimidazole Dihydrochloride; 5-Methylhistamine Dihydrochloride; 5(4)-Methylhistamine Dihydrochloride; 5-(2-Aminoethyl)-4- methylimidazole Dihydrochloride. CAS No. 36376-47-3. Molecular formula: C6H11N3.2HCl. Mole weight: 198.09. | |
| 4-(NITROOXY)BUTYL (2S)-2-(6-METHOXY-2-NAPHTHYL)PROPANOATE | Naproxcinod, a nitro compound, has been found to be a nitric oxide donor as well as a cyclooxygenase inhibitor that was once studied aginast duchenne muscular dystrophy. Uses: Nitric oxide donors. Synonyms: Naproxcinod; Nitronaproxen; HCT 3012; HCT3012; HCT-3012; AZD 3582; AZD3582; AZD-3582; Naproxen-n-butyl nitrate; 4-nitrooxybutyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate. Grades: 98%. CAS No. 163133-43-5. Molecular formula: C18H21NO6. Mole weight: 347.36. | |
| 4-(n-nonyl) benzeneboronic acid | Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM. Synonyms: 4-Nonylphenylboronic acid; (4-nonylphenyl)boronic acid. Grades: ≥98%. CAS No. 256383-45-6. Molecular formula: C15H25BO2. Mole weight: 248.2. | |
| 4-Oxo docosahexaenoic acid | 4-Oxo docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. Synonyms: 4-oxo DHA. Grades: ≥90%. CAS No. 845673-74-7. Molecular formula: C22H30O3. Mole weight: 342.5. | |
| 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride | An inhibitor of release of dopamine induced by methamphetamine. Synonyms: 1,2,3,4-Tetrahydro-4-phenyl-isoquinoline Hydrochloride; Isoquinoline, 1,2,3,4-tetrahydro-4-phenyl-, hydrochloride (1:1); Isoquinoline, 1,2,3,4-tetrahydro-4-phenyl-, monohydrochloride. Grades: ≥95%. CAS No. 6109-35-9. Molecular formula: C15H15N.HCl. Mole weight: 245.75. | |
| 4-PPBP maleate | Cas No. 201216-39-9. | |
| 4-P-PDOT | 4-P-PDOT is an antagonist of the melatonin 2 (MT2) receptor (pKi = 8.37) that displays 60-fold selectivity for MT2 over MT1. Synonyms: AH 024; cis-4-phenyl-2-Propionamidotetralin; N-(4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide. Grades: ≥98%. CAS No. 134865-74-0. Molecular formula: C19H21NO. Mole weight: 279.4. | |
| 4-Quinolone-3-carboxamide CB2 ligand | 4-Quinolone-3-carboxamide CB2 ligand is a selective, high-affinity ligand of the CB2 receptor. Synonyms: 4Q3C CB2 Ligand; N-(1-adamantyl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide. Grades: ≥98%. CAS No. 1314230-69-7. Molecular formula: C26H34N2O3. Mole weight: 422.6. | |
| 4-Quinolone-3-carboxamide furan CB2 agonist | 4-Quinolone-3-carboxamide furan CB2 agonist is an agonists of the peripheral cannabinoid (CB) receptor CB2 may have antinociceptive and anti-inflammatory effects, as well as prevent osteoporosis. Synonyms: 4Q3C CB2 Agonist; N-(1-adamantyl)-6-(furan-2-yl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide. Grades: ≥98%. CAS No. 1314230-75-5. Molecular formula: C30H36N2O4. Mole weight: 488.6. | |
| 4SC-202 | 4SC-202 is a selective and potent, orallly available inhibitor of histone deacetylases (HDAC) specific for class 1 HDAC isoenzymes, with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. 4SC-202 also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). In addition, 4SC-202 shows a broad anti-proliferative activity towards human cancer cell lines with a mean IC50 of 0.7 μM. Synonyms: 4SC202; 4SC-202; 4SC 202; domatinostat; (E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide. CAS No. 910462-43-0. Molecular formula: C23H21N5O3S. Mole weight: 447.51. | |
| 4SC-202 Tosylate | 4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones.This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, upregulated in many tumor types, are a class of enzymes that deacetylate chromatin histone proteins. Synonyms: 4SC-202; 4SC 202; 4SC202. Grades: 0.98. CAS No. 1186222-89-8. Molecular formula: C30H29N5O6S2. Mole weight: 619.711. | |
| 5,15-DPP | Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer. 5,15-DPP is a cell-permeable porphyrin derivative that selectively binds STAT3 (Kd = 880 nM). Synonyms: 5,15-Diphenylporphyrin; STAT3 Inhibitor VIII; 5,15-Diphenyl-21H,23H-porphine. Grades: ≥95%. CAS No. 22112-89-6. Molecular formula: C32H22N4. Mole weight: 462.6. | |
| 5,6-Dehydro arachidonic acid | 5,6-Dehydro arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. Synonyms: 5,6-dehydro AA; 8Z,1Z1,14Z-Eicosatrien-5-ynoic acid. Grades: ≥98%. CAS No. 58688-54-3. Molecular formula: C20H30O2. Mole weight: 302.5. | |
| 5,6-Dihydroxy-2-aminotetraline hydrobromide | 5,6-Dihydroxy-2-Aminotetraline hydrobromide is a dopamine receptor agonist. Synonyms: 6-amino-5,6,7,8-tetrahydronaphthalene-1,2-diol hydrobromide; Aminotetraline hydrobromide, 5,6-Dihydroxy-2-. Grades: 98%. CAS No. 37096-30-3. Molecular formula: C10H13NO2.HBr. Mole weight: 260.13. | |
| 5,6-Dihydroxy-N-methyl-N-propyl-aminotetraline hydrochloride | 5,6-Dihydroxy-N-methyl-N-propyl-Aminotetraline hydrochloride is a dopamine receptor agonist. Synonyms: Aminotetraline hydrochloride, 5,6-Dihydroxy-N-methyl-N-propyl-; 6-[methyl(propyl)amino]-5,6,7,8-tetrahydronaphthalene-1,2-diol;hydrochloride. Grades: 98%. CAS No. 55218-13-8. Molecular formula: C14H21NO2.HCl. Mole weight: 271.78. | |
| (±)5(6)-EET | 5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. Synonyms: (±)5,6-EpETrE. Grades: ≥95% (mixture of free acid and lactone). CAS No. 87173-80-6. Molecular formula: C20H32O3. Mole weight: 320.5. | |
| (±)5(6)-EET Ethanolamide | Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity. It binds to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of AEA. Synonyms: (±)5,6-EpETrE Ethanolamide; N-(2-hydroxyethyl)-4-[(2S,3R)-3-[(2Z,5Z,8Z)-tetradeca-2,5,8-trienyl]oxiran-2-yl]butanamide. Grades: ≥95%. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
| 5,7-Dichloro-8-hydroxy-2-methylquinoline | Chlorquinaldol is an antimicrobial agent. Uses: Anti-infective agents. Synonyms: 5,7-dichloro-2-methylquinolin-8-ol. Grades: > 98 %. CAS No. 72-80-0. Molecular formula: C10H7Cl2NO. Mole weight: 228.07. | |
| 5,7-Dichlorokynurenic acid | 5,7-Dichlorokynurenic acid has been found to be an effective NMDA receptor glycine binding site antagonist. Uses: Excitatory amino acid antagonists. Synonyms: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 131123-76-7. Molecular formula: C10H5Cl2NO3. Mole weight: 258.06. | |
| 5,7-Dichlorokynurenic acid sodium salt | The sodium salt form of 5,7-Dichlorokynurenic acid, which is an effective antagonist at the glycine site of the NMDA receptor. Synonyms: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt. Grades: ≥98% by HPLC. CAS No. 1184986-70-6. Molecular formula: C10H4Cl2NNaO3. Mole weight: 280.04. | |
| 5,8,11-Eicosatriynoic acid | 5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 μM. Synonyms: 5,8,11-ETI; Eicosa-5,8,11-triynoic acid. Grades: ≥99%. CAS No. 13488-22-7. Molecular formula: C20H28O2. Mole weight: 300.4. | |
| 5-Bromo-5-nitro-1,3-dioxane | 5-Bromo-5-nitro-1,3-dioxane is an antimicrobial compound that is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. Synonyms: Bronidox; 1,3-Dioxane, 5-bromo-5-nitro-. Grades: ≥98%. CAS No. 30007-47-7. Molecular formula: C4H6BrNO4. Mole weight: 212. | |
| 5-Carboxamidotryptamine maleate | The maleate salt form of 5-Carboxamidotryptamine, which has been found to be a 5-HT1 agonist displaying cardiovascular effects. Synonyms: 3-(2-Aminoethyl)-1H-indole-5-carboxamide (Z)-2-Butenedioate. Grades: ≥98% by HPLC. CAS No. 74885-72-6. Molecular formula: C11H13N3O.C4H4O4. Mole weight: 319.32. | |
| 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic Acid | PK11007 is an antitumor agent that targets and stabilizes wild type and mutant p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. It blocks cell migration and induces apoptosis in various cancer cell lines. Synonyms: 5-chloro-2-methylsulfonyl-4-pyrimidinecarboxylic acid; 5-chloro-2-methylsulfonylpyrimidine-4-carboxylic acid. CAS No. 38275-34-2. Molecular formula: C6H5ClN2O4S. Mole weight: 236.63. | |
| (±)-5'-Chloro-5'-deoxy-ENBA | (±)-5'-Chloro-5'-deoxy-ENBA is a selective adenosine A1 receptor agonist (Ki = 0.51, 1290, 1340 and 2740 nM at A1, A3, A2A and A2B receptors respectively). It is used as an antinociceptive. Uses: Antinociceptive. Synonyms: N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine. Grades: ≥98% by HPLC. CAS No. 103626-26-2. Molecular formula: C17H22ClN5O3. Mole weight: 379.84. | |
| 5-Chloro-7-iodo-8-quinolinol | Clioquinol, a quinoline derivative, is an antifungal and antiprotozoal agent and has also been found to have probable effect against cancer and Alzheimer's disease. Uses: Clioquinol is an antifungal and antiprotozoal agent and has also been found to have probable effect against cancer and alzheimer's disease. Synonyms: 5-chloro-7-iodoquinolin-8-ol. Grades: 95 %. CAS No. 130-26-7. Molecular formula: C9H5ClINO. Mole weight: 305.50. | |
| 5'-Fluoroindirubinoxime | 5'-Fluoroindirubinoxime is an inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3) (IC50 = 15 nM) with antiproliferative activity. It displays selectivity for FLT3 against 6 other kinases including EGFR. Synonyms: 5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'dione 3-oxime. Grades: ≥99% by HPLC. CAS No. 861214-33-7. Molecular formula: C16H10FN3O2. Mole weight: 295.27. | |
| (±)5-HETE lactone | (±) 5-HETE Lactone is a unique marker for 5-lipoxygenase activation. (±) 5-HETE Lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. It inhibits 5-LO (5-lipoxygenase) (IC50=27 μM) from rat basophilic leukemia cells. The lactone form is several times more potent. Synonyms: 6-pentadeca-1,3,6,9-tetraenyloxan-2-one; 6-[(1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraenyl]oxan-2-one. Grades: ≥98%. CAS No. 73279-37-5. Molecular formula: C20H30O2. Mole weight: 302.5. | |
| 5-HT2 antagonist 1 | A potent antagonist of 5-HT2 receptor. Synonyms: Pyrrolo[3,2-c]azepin-4(1H)-one, 5-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-5,6,7,8-tetrahydro-8-hydroxy-1-methyl-. CAS No. 191592-09-3. Molecular formula: C22H29FN4O2. Mole weight: 400.49. | |
| 5-HT3 antagonist 1 | A potent and selective antagonist of serotonin 3 (5-HT3) receptor. Synonyms: 1H-1,4-Diazepine, 1H-indazole-3-carboxamide deriv. CAS No. 129294-09-3. Molecular formula: C22H27N5O. Mole weight: 377.48. | |
| 5-HT6 antagonist 29 | A brain penetrant 5-HT6 receptor antagonist (pKi value 8.6). Synonyms: 5-HT6 antagonist 29; 497963-70-9; 3-(4-chlorophenyl)sulfonyl-1-methyl-7-piperazin-1-ylindole; hydrochloride; PD016667; E98892; 3-(4-chlorophenylsulfonyl)-1-methyl-7-(piperazin-1-yl)-1H-indole hydrochloride. Grades: 99%. CAS No. 497963-70-9. Molecular formula: C19H20ClN3O2S.HCl. Mole weight: 426.36. | |
| 5HT6-ligand-1 | 5HT6-ligand-1 is a potent 5-HT6 receptor ligand (Ki= 1.43 nM). Synonyms: 1H-Indole, 1-[(2-bromophenyl)sulfonyl]-4-[(4-methyl-1-piperazinyl)methyl]-; 1-(2-bromophenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole. CAS No. 1038988-11-2. Molecular formula: C20H22BrN3O2S. Mole weight: 448.38. | |
| 5-Hydroxy-2-pyrazinecarboxylic acid | A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide. Synonyms: 6-oxo-1H-pyrazine-3-carboxylic acid. Grades: > 98 %. CAS No. 34604-60-9. Molecular formula: C5H4N2O3. Mole weight: 140.10. | |
| 5-Hydroxy-DPAT hydrobromide | A potent and selective dopamine (DA) D2 receptor agonist developed as a PET agent. Synonyms: Hydroxy-DPAT hydrobromide, 5-; 6-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol hydrobromide; 5-OH-DPAT HBr. Grades: 99%. CAS No. 71787-83-2. Molecular formula: C16H25NO.HBr. Mole weight: 328.29. | |
| 5-hydroxy-Nω-methyl tryptamine oxalate | 5-Hydroxy-Nω-methyl tryptamine is a metabolite of serotonin in humans that has also been found in plants. Synonyms: N-methyl-5-HT; N-methyl Serotonin; N-methyl-5-hydroxy Tryptamine; 3-(2-Methylaminoethyl)indol-5-ol oxalate. Grades: ≥95%. CAS No. 15558-50-6. Molecular formula: C11H14N2O·xC2H2O4. Mole weight: 280.3. | |
| 5-Hydroxy propranolol | 5-Hydroxy propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist. Synonyms: 1-Naphthalenol, 5-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-. Grades: ≥98%. CAS No. 81907-82-6. Molecular formula: C16H21NO3. Mole weight: 275.3. | |
| 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative | 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative is a precursor to 5-Iodo-A-85380, which is a highly selective and potent ligand for AChR α4β2. It is used in radioiodination. Synonyms: (2S)-2-[[[5-(Trimethylstannyl)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylic acid, t-butyl ester. Grades: ≥98% by HPLC. CAS No. 213766-21-3. Molecular formula: C17H28N2O3Sn. Mole weight: 427.11. | |
| 5-Iodo-A-85380 dihydrochloride | 5-Iodo-A-85380 dihydrochloride is the dihydrochloride salt of 5-Iodo-A-85380, which is a highly potent and subtype-selective agonist for α4β2 and α6β2 nicotinic acetylcholine receptors. It activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes. Synonyms: Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, hydrochloride (1:2); (S)-3-(Azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride; 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1217837-17-6. Molecular formula: C9H13IN2OCl2. Mole weight: 363.03. | |
| 5-Methoxy-2-aminotetraline hydrochloride | 5-Methoxy-2-Aminotetraline hydrochloride is a dopamine receptor agonist. Synonyms: 2-amino-5-methoxytetralin HCl; 2-amino-5-methoxytetralin Hydrochloride; Aminotetraline hydrochloride, 5-Methoxy-2-; AK209995; 5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl amine HCl. Grades: 98%. CAS No. 3880-88-4. Molecular formula: C11H15NO.HCl. Mole weight: 213.7. | |
| 5-Methoxytryptamine | 5-Methoxytryptamine is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. Synonyms: Mexamine, Methoxytryptamine; 2-(5-Methoxy-1H-indol-3-yl)ethanamine. Grades: ≥98%. CAS No. 608-07-1. Molecular formula: C11H14N2O. Mole weight: 190.24. | |
| 5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride | M 30 dihydrochloride is a potent and brain selective inhibitor of monoamine oxidase (MAO) with EC50 values of 37 and 57 nM for MAO-A and MAO-B, respectively. M 30 decreases cell death rates and apoptotic DNA damage, exhibiting neuroprtective properties. Synonyms: 5-[[methyl(prop-2-ynyl)amino]methyl]-8-quinolinol;dihydrochloride; 5-[[methyl(prop-2-ynyl)amino]methyl]quinolin-8-ol;dihydrochloride. Grades: ≥ 98 % by HPLC. CAS No. 64821-19-8. Molecular formula: C14H16Cl2N2O. Mole weight: 299.20. | |
| 5-Methylfurmethiodide | 5-Methylfurmethiodide is a selective muscarinic agonist in mammals. Uses: Parasympathomimetics. Synonyms: (5-Methyl-2-furyl)methyltrimethylammonium iodide; Trimethyl(5-methylfurfuryl)ammonium Iodide; 5-Methylfurmethide; 5-Methylfurmethide, Iodide; 5-Methylfurtrethonium Iodide; Methyl-furmethide; Methylfurmethide; Methylfurmethide Iodide; Methylfurmetide; Preparation 7070; N,N,N,5-Tetramethyl-2-furanmethanaminium Iodide. Grades: ≥99% by HPLC. CAS No. 1197-60-0. Molecular formula: C9H16INO. Mole weight: 281.14. | |
| 5-Nonyloxytryptamine oxalate | 5-Nonyloxytryptamine oxalate is a potent agonist of the serotonin (5-HT) receptor 5-HT1Dβ with an EC50 value of 68 nM for adenylate cyclase activity in CHOKM6 cells transfected with the human 5-HT1Dβ receptor. It is several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Synonyms: 5-(Nonyloxy)-1H-Indole-3-ethanamine ethanedioate; 5-(Nonyloxy)tryptamine oxalate; 5-Nonyloxytryptamine oxalate. Grades: ≥99% by HPLC. CAS No. 157798-13-5. Molecular formula: C19H30N2O.C2H2O4. Mole weight: 392.49. | |
| 5-OMe-UDP trisodium salt | 5-OMe-UDP trisodium salt is a P2Y6 agonist with EC50 value of 0.08 μM. Synonyms: 5-Methoxyuridine 5'-diphosphate trisodium salt. Grades: ≥98% by HPLC. CAS No. 1207530-98-0. Molecular formula: C10H13N2Na3O13P2. Mole weight: 500.13. | |
| 5-OxoETE | 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase. Synonyms: 5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5-KETE; 5-ketoeicosatetraenoic acid. Grades: >98%. CAS No. 106154-18-1. Molecular formula: C20H30O3. Mole weight: 318.46. | |
| 5-OxoETE methyl ester | 5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE. Synonyms: 5-KETE methyl ester. Grades: ≥95%. CAS No. 74785-00-5. Molecular formula: C21H32O3. Mole weight: 332.5. | |
| 5(S),6(R)-DiHETE | 5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. 5(S),6(R)-DiHETE is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM. Synonyms: (5S,6R,7E,9E,11Z,14Z)-5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid. Grades: ≥95%. CAS No. 82948-88-7. Molecular formula: C20H32O4. Mole weight: 336.5. | |
| 5-Trans latanoprost | Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Grades: ≥98%. CAS No. 903549-49-5. Molecular formula: C23H34O5. Mole weight: 390.5. | |
| 5(Z),8(Z),11(Z)-Eicosatrienoic acid ethanolamide | 5(Z),8(Z),11(Z)-Eicosatrienoic acid ethanolamide is essentially identical to AEA in its agonist binding to CB1 and CB2 receptors. Synonyms: Mead acid ethanolamide; (5E,8E,11E)-N-(2-hydroxyethyl)icosa-5,8,11-trienamide. Grades: ≥98%. CAS No. 169232-04-6. Molecular formula: C22H39NO2. Mole weight: 349.6. | |
| 6-(4-Methoxyphenyl)-3-pyridazinamine | 6-(4-Methoxyphenyl)-3-pyridazinamine is an aminopyridazine derivative that acts as a GABAA receptor antagonist. Synonyms: 6-(4-methoxyphenyl)pyridazin-3-amine. Grades: ≥98%. CAS No. 4776-87-8. Molecular formula: C11H11N3O. Mole weight: 201.2. | |
| 6,7-Dihydroxy-2-aminotetraline hydrobromide | 6,7-Dihydroxy-2-Aminotetraline hydrobromide is a dopamine receptor agonist. Synonyms: (+/-)-Adtn hydrobromide; NSC-287353; (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide; 6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol hydrobromide; Aminotetraline hydrobromide, 6,7-Dihydroxy-2-. Grades: 99%. CAS No. 13575-86-5. Molecular formula: C10H13NO2.HBr. Mole weight: 260.13. | |
| 6,7-Dihydroxy-N-methyl-N-propyl-aminotetraline hydrobromide | 6,7-Dihydroxy-N-methyl-N-propyl-Aminotetraline hydrobromide is a dopamine receptor agonist. Synonyms: 6-[methyl(propyl)amino]-5,6,7,8-tetrahydronaphthalene-2,3-diol hydrobromide; Aminotetraline hydrobromide, 6,7-Dihydroxy-N-methyl-N-propyl-. Grades: 98%. CAS No. 1246094-90-5. Molecular formula: C14H21NO2.HBr. Mole weight: 316.23. | |
| 6,7-Dimethoxy-2-aminotetraline hydrobromide | 6,7-Dimethoxy-2-Aminotetraline hydrobromide is a dopamine receptor agonist. Synonyms: Aminotetraline hydrobromide, 6,7-Dimethoxy-2-; 6,7-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrobromide. Grades: 99%. CAS No. 40069-26-9. Molecular formula: C12H17NO2.HBr. Mole weight: 288.18. | |
| 6877002 | Cas No. 433249-94-6. | |
| 6-Aminonicotinamide | 6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase (Ki = 0.46 μM). 6-Aminonicotinamide is a PGD inhibitor and apoptosis inducer. Uses: Teratogens. Synonyms: 6-aminopyridine-3-carboxamide. Grades: 95 %. CAS No. 329-89-5. Molecular formula: C6H7N3O. Mole weight: 137.14. | |
| 6-Aminophenanthridine | 6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz. Synonyms: 6-phenanthridinamine; phenanthridin-6-amine. Grades: ≥ 95 %. CAS No. 832-68-8. Molecular formula: C13H10N2. Mole weight: 194.23. | |
| 6-Chloromelatonin | 6-Chloromelatonin is a potent agonist of the melatonin receptors, which is active at nanomolar concentrations. It shows higher affinity for binding to hamster brain membrane and chicken retina than melatonin. It has antiproliferative activity. Synonyms: N-[2-(6-Chloro-5-methoxyindol-3-yl)ethyl]acetamide; N-Acetyl-6-chloro-5-methoxytryptamine. Grades: ≥99% by HPLC. CAS No. 63762-74-3. Molecular formula: C13H15ClN2O2. Mole weight: 266.73. | |
| 6'-GNTI dihydrochloride | 6'-GNTI dihydrochloride is a potent and selective κ/δ-opioid heterodimer receptor agonist (EC50 = 39.8, 112.5 and > 1000 nM for κ/δ, κ/μ and δ/μ, respectively) without effecting on opioid receptor homodimers (EC50 > 1000 nM). 6'-GNTI exhibits tissue-specific analgesic effects in vitro. Synonyms: 6''-Guanidinyl-17-(cyclopropylmethyl)-6,7-dehydro-4,5a-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinan dihydrochloride. Grades: ≥97% by HPLC. Molecular formula: C27H29N5O3.2HCl. Mole weight: 544.48. | |
| 6H-Indeno[1,2-e]tetrazolo[1,5-b][1,2,4]triazin-6-one | KP372-1 is a specific Akt inhibitor that demonstrates at least 10-fold selectivity against a panel of additional kinase targets, including CDK1, ERK1, GSK3β, LCK, MEK1, PKA, PKC, and S6K. It blocks Akt signalling through the PI3K pathway, and inhibits cell proliferation while inducing apoptosis of thyroid cancer cells. Synonyms: 6H-Indeno[1,2-e]tetrazolo[1,5-b][1,2,4]triazin-6-one. Grades: ≥95%. CAS No. 1374996-60-7. Molecular formula: C20H8N12O2. Mole weight: 448.4. | |
| 6H-?Pyrimido[4, ?5-?b]?[1, ?4]?benzodiazepin-?6-?one, 5, ?11-?dihydro-?2-?[[2-?methoxy-?4-? (4-?methyl-?1-?piperazinyl) ?phenyl]?amino]?-?5, ?11-?dimethyl- | An effective inhibitior of ERK5, could probably be used as an antitumor agent. IC50: 0.19μM(EC50 for cellular),of 0.087 μM(for enzymatic) and 0.087 μM(for LRRK2). Uses: An effective inhibitior of erk5 and could probably be used as an antitumor agent. Synonyms: ERK5-IN-1; ERK5 IN 1; ERK5IN1; CHEMBL1673039; SCHEMBL618262; BDBM50337127; ZINC66066276; CS-4938; HY-14403. Grades: 98%. CAS No. 1234479-76-5. Molecular formula: C25H29N7O2. Mole weight: 459.54. | |
| 6-Hydroxybuspirone hydrochloride | A major active metabolite of Buspirone, a 5-HT1A partial agonist, with higher bioavailability than that of buspirone. Synonyms: BMS 528215 hydrochloride; 6OHB; 6-OH-Bu; 6-hydroxy-8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grades: 98%. CAS No. 2108825-99-4. Molecular formula: C21H31N5O3.HCl. Mole weight: 437.96. | |
| 6-Hydroxy-DPAT hydrobromide | A weak dopamine receptor agonist. Synonyms: Hydroxy-DPAT hydrobromide, 6-; CTK8H1644; 6-OH-DPAT HBr; 6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol hydrobromide. Grades: 99%. CAS No. 76135-29-0. Molecular formula: C16H25NO.HBr. Mole weight: 328.29. | |
| 6-Hydroxyflavone | 6-Hydroxyflavone, a naturally occurring flavonoid, binds to GABAA receptors with moderate affinity and acts as a partial agonist of GABAA receptors. Synonyms: 6-Hydroxy-2-phenyl-4-benzopyrone; 6-HF. Grades: ≥97%. CAS No. 6665-83-4. Molecular formula: C15H10O3. Mole weight: 238.24. | |
| 6-Methyl Pergolide | 6-Methyl Pergolide is a dopamine agonist. It is also a potent antagonist of 5-HT2A and 5-HT2B receptors on porcine cardiac valves. It increases serum corticosterone concentration in rats at a dose of 3 mg/kg. It also activates brain dopaminergic receptors and lowers cranial DOPAC levels in rats. Uses: 6-methyl pergolide activates brain dopaminergic receptors and lowers cranial dopac levels. Synonyms: LY 116467; LY-116467; LY116467; (8β )-6-Methyl-8-[(methylthio)methyl]ergoline; LY062; LY116467; (6aR, 9R, 10aR)-7-methyl-9-(methylsulfanylmethyl)-6, 6a, 8, 9, 10, 10a-hexahydro-4H-indolo[4, 3-fg]quinoline; LY-116467; 6-Methyl-8-((methylthio)methyl)ergoline (8beta). Grades: 98%. CAS No. 57202-76-3. Molecular formula: C17H22N2S. Mole weight: 286.43. | |
| 6-O-butyl castanospermine | Celgosivir, an effective α-glucosidase I inhibitor, has been found to be related to viral maturation and is still under Phase I/II trial against Dengue. IC50: 16 and 47 umol/L (through plaque assay and a cytopathic assay). Uses: Celgosivir is an effective α-glucosidase i inhibitor that has been found to be related to viral maturation. Synonyms: 60-P-001; MBI-3253; MDL-28574; MX-3253; VIR-222; 60P001; MBI3253; MDL28574; MX3253; VIR222; 60 P 001; MBI 3253; MDL 28574; MX 3253; VIR 222; Celgosivir; BuCast; 6-O-Butanoylcastanospermine; UNII-895VG117HN; B-CAST; AC1L1TTH. Grades: 95%. CAS No. 121104-96-9. Molecular formula: C12H21NO5. Mole weight: 259.30. | |
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