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Cefuroxime sodium
Cefuroxime sodium is a second-generation cephalosporin antibiotic resistant to beta-lactamase. It has a broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria. Uses: Anti-bacterial agents. Alternative Names: Anaptivan; Biociclin; Biofurex; (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; Cefurin; Duxima; Novocef; Zinacef. Grades: ≥95%. CAS No. 56238-63-2. Molecular formula: C16H15N4NaO8S. Mole weight: 446.36.
Cefuzonam
It is produced by the strain of Semisynthetic third generation cephalosporin for injection. It has the third-generation cephalosporin commonness. It is characterized by stronger anti-gram-positive bacterial activity than other species of the same generation. Alternative Names: Cefuzoname; Cefuzonamum; 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1,2,3-thiadiazol-5-ylsulfanyl)methyl]-3,4-didehydrocepham-4-carboxylic acid. Grades: ≥ 95%. CAS No. 82219-78-1. Molecular formula: C16H15N7O5S4. Mole weight: 513.59.
Celastramycin A
Celastramycin A is a bioactive compound isolated from endophytic bacteria. Celastramycin A exhibited high activity against a series of multiresistent bacteria and mycobacteria. It inhibits the growth of Gram-positive bacteria and mycobacteria with minimal inhibitory concentration (MIC). Celastramycin A suppresses the production of interleukin-8 in human umbilical vein endothelial cells as stimulated by tumor necrosis factor-α with IC50 of 0.01 μg/ml. It can also be used as a lead compound for novel immunosuppressive agents. Grades: ≥97%. CAS No. 491600-94-3. Molecular formula: C17H18Cl3NO3. Mole weight: 390.69.
Celastrol
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice. Alternative Names: Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid. Grades: >98%. CAS No. 34157-83-0. Molecular formula: C29H38O4. Mole weight: 450.61.
Celesticetin A
It is produced by the strain of Streptomyces caelestis NRRL 2418. It has anti-gram-positive bacterial activity. Alternative Names: Celesticetin; CHEBI:156421; D-erythro-a-D-galacto-Octopyranoside, 2-[(2-hydroxybenzoyl)oxy]ethyl6,8-dideoxy-7-O-methyl-6-[[[(2S)-1-methyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-; 1-Methyl-L-prolin-{(1R,2R)-2-methoxy-1-[(2R)-3c,4c,5t-trihydroxy-6t-(2-salicyloyloxy-aethylmercapto)-tetrahydro-pyran-2r-yl]-propylamid}; U-5524. CAS No. 2520-21-0. Molecular formula: C24H36N2O9S. Mole weight: 528.61.
Celesticetin B
It is produced by the strain of Streptomyces caelestis NRRL 2418. It has anti-gram-positive bacterial activity. Alternative Names: Isobutyric acid 2-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-{(R)-2-methoxy-1-[(1-methyl-pyrrolidine-2-carbonyl)-amino]-propyl}-tetrahydro-pyran-2-ylsulfanyl)-ethyl ester. CAS No. 42715-01-5. Molecular formula: C21H38N2O8S. Mole weight: 478.60.
Celesticetin C
It is produced by the strain of Streptomyces caelestis NRRL 2418. It has anti-gram-positive bacterial activity. Alternative Names: 2-Amino-benzoic acid 2-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-{(R)-2-methoxy-1-[(1-methyl-pyrrolidine-2-carbonyl)-amino]-propyl}-tetrahydro-pyran-2-ylsulfanyl)-ethyl ester. CAS No. 42715-02-6. Molecular formula: C24H37N3O8S. Mole weight: 527.63.
Cellocidin
It is produced by the strain of Streptomyces chibaensis. It can resist gram-positive bacteria and negative bacteria (individual). It has a broad antibacterial, antifungal and antitumor profile due to its ability to react with endogenous thiols like cysteine and glutathione. Alternative Names: Aquamycin; Butynesiamide; Lenamycin; ACETYLENEDICARBOXAMIDE; 2-Butynediamide; Lenamycin; Renamycin; Acetylene dicarboxamide; Acetylenedicarboxylic acid diamide; Acetylendicarbonsaeureamide. Grades: >98% by HPLC. CAS No. 543-21-5. Molecular formula: C4H4N2O2. Mole weight: 112.09.
Cepacidin A
Cepacidin A is an antifungal cyclic peptide antibiotic produced by Pseudomonas cepacia AF 2001. Alternative Names: 2-[25-amino-22-(2-amino-1-hydroxy-2-oxoethyl)-19-[6-amino-4-hydroxy-2-(3,4,5-trihydroxyoxan-2-yl)oxypentadecyl]-12-[hydroxy-(4-hydroxyphenyl)methyl]-6,15-bis(hydroxymethyl)-2,5,8,11,14,17,21,24-octaoxo-1,4,7,10,13,16,20,23-octazacycloheptacos-9-yl]acetic. CAS No. 157184-36-6. Molecular formula: C52H85N11O22. Mole weight: 1216.29.
Cepacin A
It is produced by the strain of Pseudomonas cepacia SC 11783. It has anti-gram positive and negative bacterial activity. Alternative Names: 2(3H)-Furanone, 4,5-dihydro-5-(3-hydroxy-4-oxododeca-1,6,7-trien-9,11-diynyl)-; 2(5H)-Furanone, 5-(3-(3-(1,2-heptadiene-4,6-diynyl)oxiranyl)-3-hydroxy-1-propenyl)dihydro-; 4,5-Dihydro-5-(3-hydroxy-4-oxododeca-1,6,7-trien-9,11-diynyl)-2(3H)-furanone. CAS No. 91682-95-0. Molecular formula: C16H14O4. Mole weight: 270.28.
Cepacin B
It is produced by the strain of Pseudomonas cepacia SC 11783. It has anti-gram positive and negative bacterial activity. Alternative Names: 4,5-Dihydro-5-(2,3:4,5-diepoxy-1-hydroxydodeca-6,7-dien-9,11-diynyl)-2(3H)-furanone; 2(5H)-Furanone, 5-((3'-(1,2-heptadiene-4,6-diynyl)(2,2'-bioxiran)-3-yl)hydroxymethyl)dihydro-; 2(3H)-Furanone, 4,5-dihydro-5-(2,3:4,5-diepoxy-1-hydroxydodeca-6,7-dien-9,11-diynyl)-; CEPACIN-B. CAS No. 91682-94-9. Molecular formula: C16H14O5. Mole weight: 286.28.
Cepafungin I
Cepafungin I is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice. Alternative Names: 2,4-Dodecadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazabicyclododec-3-en-8-yl)amino)carbonyl)propyl)-11-methyl-, (5S-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-. CAS No. 130743-08-7. Molecular formula: C28H46N4O6. Mole weight: 534.67.
Cepafungin III
Cepafungin III is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice. Alternative Names: 2,4-Decadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-9-methyl-, (SS-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-. CAS No. 130743-09-8. Molecular formula: C26H42N4O6. Mole weight: 506.63.
Cephabacin F1
It is produced by the strain of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-278, YK-280 and YK-431. It has anti-gram positive and negative bacterial activity. The Cephabacin F series is stable and has inhibitory effect on cephalosporin enzyme. CAS No. 95041-98-8. Molecular formula: C26H41N9O11S. Mole weight: 687.72.
Cephabacin M1
It is produced by the strain of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-278, YK-280 and YK-431. It has anti-gram positive and negative bacterial activity. The Cephabacin M series is stable and has inhibitory effect on cephalosporin enzyme. CAS No. 99332-96-4. Molecular formula: C31H50N8O13S. Mole weight: 774.84.
Cephabacin M6
It is produced by the strain of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-278, YK-280 and YK-431. It has anti-gram positive and negative bacterial activity. The Cephabacin M series is stable and has inhibitory effect on cephalosporin enzyme. Alternative Names: Cephabacin M(sub 6); L-Valinamide, L-alanyl-L-seryl-L-ornithyl-L-valyl-L-ornithyl-N-(4-((7-((5-amino-5-carboxyl-1-oxopentyl)amino)-2-carboxy-7-methoxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-3-en-3-yl)methoxy)-1-(2-amino-2-oxoethyl)-2-hydroxy-4-oxobutyl)-, (6R-(6-alpha,7-alpha,7(R*)))-; Cephabacin M6; LS-161269. CAS No. 99313-73-2. Molecular formula: C47H79N13O18S. Mole weight: 1146.27.
Cephaibol A
It is produced by the strain of Acremonium tubakii DSM 12774. It has anti-gram-positive bacterial activity, but no anti-gram-negative bacterial activity. It also has the effect of deworming and anti-ectoparasite. Molecular formula: C82H127N17O20. Mole weight: 1670.98.
Cephaibol B
It is produced by the strain of Acremonium tubakii DSM 12774. It has anti-gram-positive bacterial activity, but no anti-gram-negative bacterial activity. Molecular formula: C83H129N17O20. Mole weight: 1685.01.
Cephaibol D
It is produced by the strain of Acremonium tubakii DSM 12774. It has weak antibacterial activity. Molecular formula: C80H123N17O20. Mole weight: 1642.93.
Cephalonic acid
It is produced by the strain of Cephalosporium caerulens. It has weak anti-staphylococcus aureus activity. Alternative Names: Ophiobolin D; 8-Hydroxy-5-oxoophiobola-3,6,19-trien-25-oic acid; Dicyclopenta(a,d)cyclooctene-4-carboxylic acid, 7-((1S)-1,5-dimethyl-4-hexenyl)-3,5,6,6a,7,8,9,9a,10,10a-decahydro-5-hydroxy-1,9a-dimethyl-3-oxo-, (6aS,7R,9aR,10aR)-. CAS No. 18456-04-7. Molecular formula: C25H36O4. Mole weight: 400.55.
Cephaloridine
It is produced by the strain of Semisynthetic first generation cephalosporin for injection. Cephaloridine had the same antibacterial spectrum as Cephalothin, but had stronger antibacterial effect than Cephalothin. Oral malabsorption, The drug is excreted 75%-80% in the urine by injection for 24h. The half-life of normal plasma elimination was 1.5h, and the binding rate of plasma protein was 22%. Alternative Names: cefaloridine; Cefaloridin; Cephaloridin; Cephaloridinum; Cefalorizin; Cephalomycine; N-(7-((2-Thienyl)acetamido)ceph-3-em-3-ylmethyl)pyridinium-4-carboxylate; 7-((2-Thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanic acid. Grades: 95%. CAS No. 50-59-9. Molecular formula: C19H17N3O4S2. Mole weight: 415.48.
Cephalosporin C Zinc Salt
Cephalosporin C zinc salt is the salt form of cephalosporin C, which is an antibiotic isolated from fungi of the genus Acremonium. Cephalosporin C has weak resistance to gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Alternative Names: (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Zinc Salt; [6R-[6α,7β(R*)]]-3-[(Acetyloxy)methyl]-7-[(5-amino-5-carboxy-1-oxopentyl)amino]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Zinc Salt; (6R,7R)-3-tyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Zinc Salt; Zinc (6R-(6alpha,7beta(R*)))-3-(acetoxymethyl)-7-((5-amino-5-carboxylato-1-oxopentyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate; Zinc cephalosporin C; (6R,7R)-3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate zinc. Grades: 95%. CAS No. 59143-60-1. Molecular formula: C16H19N3O8SZn. Mole weight: 478.79.
Cephalothin
It is produced by the strain of Semisynthetic first generation cephalosporin for injection. Alternative Names: Cefalotin; Cephalotin; Cefalothin; Cephalothinum; Cefalonium Impurity A; Keflin; Cemastin; Cefalotina; Cefalotine; 7-(2-Thienylacetamido)cephalosporanic acid; 6R-trans-3-((Acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-carboxylic acid. Grades: 98%. CAS No. 153-61-7. Molecular formula: C16H16N2O6S2. Mole weight: 396.44.
Cephamycin A
It is produced by the strain of Streptomyces lactamdurans, Str. chartrensis, Str. griseus, Str. cinnamonensis, Str. fimbiiatus, Str. halstddii, Str. rochei, Str. vuridochromogene. Cephalomycin A showed weak activity against gram-positive and negative bacteria. Alternative Names: SCHEMBL585134; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(5-amino-5-carboxyvaleramido)-3-(hydroxymethyl)-7-methoxy-8-oxo-, p-hydroxy-alpha-methoxycinnamate (ester) hydrogen sulfate (ester), D-; (6R)-7t-((R)-5-amino-5-carboxy-pentanoylamino)-7c-methoxy-3-[2-methoxy-3-(4-sulfooxy-phenyl)-acryloyloxymethyl]-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS No. 34279-78-2. Molecular formula: C25H29N3O14S2. Mole weight: 659.64.
Cephamycin B
It is produced by the strain of Streptomyces lactamdurans, Str. chartrensis, Str. griseus, Str. cinnamonensis, Str. fimbiiatus, Str. halstddii, Str. rochei, Str. vuridochromogene. Cephalomycin B showed weak activity against gram-positive and negative bacteria. CAS No. 34279-77-1. Molecular formula: C25H29N3O11S. Mole weight: 579.58.
Cephamycin C
It is produced by the strain of Streptomyces lactamdurans, Str. chartrensis, Str. griseus, Str. cinnamonensis, Str. fimbiiatus, Str. halstddii, Str. rochei, Str. vuridochromogene. Cephalomycin C was resistant to gram-positive bacteria (weak) and negative bacteria, with low toxicity, and mice could tolerate intraperitoneal injection of 10 g/kg. Used as raw material for semisynthetic cephalosporin. Alternative Names: Cephemimycin; antibiotic 842A; (6R,7S)-3-[[(aminocarbonyl)oxy]methyl]-7alpha-[[(R)-5-amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; A16886B; A 16886B; A-16886B. Grades: 95%. CAS No. 38429-35-5. Molecular formula: C16H22N4O9S. Mole weight: 446.43.
Cephapirin benzathine
Cephapirin benzathine is a first-generation cephalosporin with a broad spectrum of activity against gram-positive and gram-negative organisms. Its resistance to β-lactamase is higher than that of the penicillin family. commonly used in the veterinary field. Alternative Names: Cefapirin benzathine. CAS No. 97468-37-6. Molecular formula: C50H54N8O12S4. Mole weight: 1087.27.
Cephemimycin
It is produced by the strain of Streptomyces jumonjinensis (NRRL 5741). It has weak antibacterial and antifungal activity. The removed side chain can be used as raw material for semisynthetic cephalosporin. Alternative Names: Cephamycin C; antibiotic 842A; (6R,7S)-3-[[(aminocarbonyl)oxy]methyl]-7alpha-[[(R)-5-amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; A16886B; A 16886B; A-16886B. CAS No. 34279-51-1. Molecular formula: C16H22N4O9S. Mole weight: 446.43.
Cephradine
It is produced by the strain of Semisynthetic first generation cephalosporin. It has the commonness of the first generation cephalosporin and its antibacterial action is similar to that of cefalexin. It is characterized by that it can be injected or given orally. Uses: A first generation cephalosporin antibiotic. Alternative Names: Cefradine; Cephradin; Anspor; Sefril; 7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacid; Velosef; Cefradina; Cefradinum; (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid. Grades: 95%. CAS No. 38821-53-3. Molecular formula: C16H19N3O4S. Mole weight: 349.41.
Cercosporamide
Cercosporamide, a natural antifungal phytotoxin produced by Cercosporidium sp. MST-FP1899, has been found to be a selective Mnk inhibitor and shows probable antileukemic effects. Uses: Insecticide. Alternative Names: (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide; (S)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancarboxamide; (-)-Cercosporamide. Grades: >95%. CAS No. 131436-22-1. Molecular formula: C16H13NO7. Mole weight: 331.28.
Cerebroside A
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Molecular formula: C41H75NO9. Mole weight: 726.03.
Cerebroside B
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Alternative Names: 1-O-beta-d-glucopyranosyl-(2s,3r,4e,8e)-2-[(2r)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol; 1-O-Pivaloyl-glycerin; 1-pivaloyloxypropane-2,3-diol; Propanoic acid,2,2-dimethyl-,2,3-dihydroxypropyl ester; glucocerebroside. Grades: >97%. CAS No. 88642-46-0. Molecular formula: C41H77NO9. Mole weight: 728.05.
Cerebroside D
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Cerebroside D is a glycoceramide compound with antitumor activity. Study on murine experimental colitis showed that cerebroside D reduced weight loss and the macroscopic as well as microscopic appearances of colitis induced by dexran sulfate sodium. Cerebroside D also inhibited proliferation and induced apoptosis of T cells activated by concanavalin A or anti-CD3 plus anti-CD28 antibodies. Alternative Names: (2S,2'R,3R,4E,8E)-N-2'-hydroxyoctadecanoyl-1-O-(β-D-glucopyranosyl)-9-methyl-4,8-sphingadienine; (R)-2-Hydroxy-octadecanoic acid [(3E,7E)-(1S,2R)-2-hydroxy-8-methyl-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-heptadeca-3,7-dienyl]-amide. Grades: 96.5%. CAS No. 113773-89-0. Molecular formula: C43H81NO9. Mole weight: 756.117.
Cerexin A
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. Alternative Names: Antibiotic 60-6; CEREXIN-A; LS-52766. CAS No. 55467-31-7. Molecular formula: C63H103N15O19. Mole weight: 1374.58.
Cerexin B
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 55467-34-0. Molecular formula: C69H107N15O17. Mole weight: 1418.67.
Cerexin B1
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 70943-81-6. Molecular formula: C66H99N15O18. Mole weight: 1390.58.
Cerexin B4
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 70943-84-9. Molecular formula: C66H101N15O18. Mole weight: 1392.59.
Cerexin D4
It is produced by the strain of Bac.cereus Gp-3. It has anti-gram-positive bacterial activity. CAS No. 70943-88-3. Molecular formula: C66H101N15O17. Mole weight: 1376.60.
Cervicarcin
It is produced by the strain of Streptomyces ogaensis 1390. It had a strong inhibitory effect on sarcoma 180 and sarcoma NF, but had a weak effect on sarcoma 37, Ehrman's ascites cancer and Friend leukemia. Alternative Names: NSC65380; NSC 65380; NSC-65380; 1,3,4,5,10-Pentahydroxy-2-methyl-3-[(3-methyloxiran-2-yl)carbonyl]-1,2,3,4-tetrahydro-4a,9a-epoxyanthracen-9(10H)-one; 4a,9a-Epoxy-3-(2,3-epoxybutyryl)-1,2,3,4,4a,9a-hexahydro-1,3,4,5,10-pentahydroxy-2-methyl-anthrone. CAS No. 18700-78-2. Molecular formula: C19H20O9. Mole weight: 392.36.
Cervinomycin A2
It is produced by the strain of Amycolata autotrophica. It has anti-gram-positive bacteria (MIC is 0.04-0.12 μg/mL) and weak anti-Saccharomyces cerevisiae (MIC is 100 μg/mL) activity. Alternative Names: Antibiotic 167B; Antibiotic 4181A; (1)Benzopyrano(2',3':6,7)naphth(2,1-g)oxazolo(3,2-b)isoquinoline-8,14,15,17-tetrone, 1,2,3a,4-tetrahydro-11,12-dimethoxy-16-hydroxy-3a-methyl-, (-)-; Cerubinomycin A2; 167-B. CAS No. 82658-22-8. Molecular formula: C29H21NO9. Mole weight: 527.48.
Cetirizine methyl ester dihydrochloride
Cetirizine methyl ester dihydrochloride is a derivative of cetirizine, an antihistamine drug for the relief of symptoms of allergy and cold like sneezing and itching. Alternative Names: Methyl 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetate dihydrochloride. CAS No. 83881-48-5. Molecular formula: C22H29Cl3N2O3. Mole weight: 475.8.
Cetoniacytone A
It is produced by the strain of Actinomyces sp. Lu 9419. Cetoniacytone A has weak activity against gram-positive and negative bacteria. It can inhibit the growth of HEPG2 and MCF7 human tumor cell lines. GI50 is 3.2 ?ol/L. CAS No. 496775-48-5. Molecular formula: C9H11NO5. Mole weight: 213.19.
Cetoniacytone B
It is produced by the strain of Actinomyces sp. Lu 9419. It can inhibit the growth of HEPG2 and MCF7 human tumor cell lines. GI50 is 4.4 ?ol/L. Alternative Names: C21249; (1r,5s,6r)-4-amino-5-hydroxy-1-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one. Molecular formula: C7H9NO4. Mole weight: 171.15.
CGP-9000
CGP-9000 is a semisynthetic cephalosporin which has a wide antibacterial spectrum. Its antibacterial activity was similar to that of cefalexin in vitro, but the effect of oral administration was 2-7 times stronger than that of cefalexin and cefradine in mice. Alternative Names: CGP 9000; BRN 0587499. Molecular formula: C16H19N3O5S. Mole weight: 365.40.
Chaetiacandin
It is produced by the strain of Monochaetia dimorphospora(Papulacadin). The activity of Chaetiacandin against Candida albicans was stronger than amphotericin B and 5-FC. Alternative Names: LS-71333; D-Glucitol, 1,5-Anhydro-1-C-(2,4-Dihydroxy-6-(Hydroxymethyl)Phenyl)-4-O-(6-O-(1-Oxo-2,4-Decadienyl)-Beta-D-Galactopyranosyl)-, 3-(7-Hydroxy-2,4,8,10-Tetradecatetraenoate). CAS No. 96989-32-1. Molecular formula: C43H60O16. Mole weight: 832.92.
Chaetoatrosin
It is produced by the strain of Chaetomium atrobrunneum F449. Chaetoatrosin inhibits chitin synthase of IC50 of 104 ?/mL. Chaetoatrosin has antifungal activity including Pyricularia oryzae, Botrytis cinerea, Cryptococcus neoformans, Trichophyton mentagrophytea and so on. Alternative Names: Chaetoatrosin A; chaetoatrosin-a; SCHEMBL12800163. Molecular formula: C14H14O5. Mole weight: 262.26.
Chaetoglobosin A
Chaetoglobosin A, a sort of a mycotoxic cytochalasan compound, could be obtained from endophytic fungus C. globosum and has been found to exhibit antibacterial and nematicidal activities. It is also found to be effective in inducing apoptosis of cancer cells. Alternative Names: chaetoglobosins. Grades: ≥98%. CAS No. 50335-03-0. Molecular formula: C32H36N2O5. Mole weight: 528.64.
Chaetoviridin A
Chaetoviridin A is a fungal metabolite isolated from Chaetomium globosum, which exhibits antifungal activity against plant pathogenic fungi. Grades: >95% by HPLC. CAS No. 128252-98-2. Molecular formula: C23H25ClO6. Mole weight: 432.9.
Chainin
It is produced by the strain of Chainia sp. It has anti-yeast and aspergillus Niger fungal activity. Alternative Names: 2-(n-Butyl)-16-methyl-3,5,7,9,11,13,15,26,27-nonahydroxyoctacosa-16,18,20,22,24-pentaenoic acid, 27-lactone. CAS No. 38264-25-4. Molecular formula: C33H54O10. Mole weight: 610.77.
Chalcomycin
It is produced by the strain of Streptomyces bikiniensis. It is mainly against gram-positive bacteria and also has effect on mycobacterium. Alternative Names: Miconomycin; CHALCOMYCIN; J-013176; (1S,2E,5S,7S,8R,9S,10E,14R,15R,16S)-5-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]-8-[(2S,3R,4S,6R)-3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl]oxy-5,7,9,14-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadeca-2,10-diene-4,12-dione; Chalcomycin A; NSC 150439. CAS No. 20283-48-1. Molecular formula: C35H56O14. Mole weight: 700.81.
Chandrananimycin A
It is produced by the strain of Actinomadura sp. M048. Chandrananimycin A has anti-mucor activity, and anti-CCL HT29, MFXF 529L, MACL McF-7 et al tumor cell activity. Alternative Names: Acetamide, N-(9-hydroxy-3-oxo-3H-phenoxazin-2-yl)-. CAS No. 664355-12-8. Molecular formula: C14H10N2O4. Mole weight: 270.24.
Chandrananimycin B
It is produced by the strain of Actinomadura sp. M048. Chandrananimycin B has anti-mucor activity, and anti-CCL HT29, MFXF 529L, MACL McF-7 et al tumor cell activity. Alternative Names: Acetamide, 2-hydroxy-N-(3-oxo-3H-phenoxazin-2-yl)-; SCHEMBL3777988; 2-(2-hydroxyacetyl)amino-3h-phenoxazin-3-one. CAS No. 664355-13-9. Molecular formula: C14H10N2O4. Mole weight: 270.24.
Chandrananimycin C
It is produced by the strain of Actinomadura sp. M048. Chandrananimycin C has anti-mucor activity, and anti-CCL HT29, MFXF 529L, MACL McF-7 et al tumor cell activity. It is also have anti-gram-positive bacteria and algae activities. Molecular formula: C17H16N2O3. Mole weight: 296.32.
Chartreusin
It is produced by the strain of Streptomyces chartreusis. It has the activity of anti-gram-positive bacteria and mycobacterium. Chartreusin is an antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA; inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals; a potent inhibitor of topoisomerase II. Alternative Names: Lambdamycin; Antibiotic X-465A; NSC 5159; (1R,2R,3aS,8aR)-1-[(Z)-5-hydroxy-3-(hydroxymethyl)pent-3-enyl]-1-(hydroxymethyl)-2,5-dimethyl-2,3,4,7,8,8a-hexahydroazulene-3a-carbaldehyde; 10-[[6-Deoxy-2-O-(6-deoxy-3-O-methyl-α-D-galactopyranosyl)-β-D-galactopyranosyl]oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione. Grades: >99% by HPLC. CAS No. 6377-18-0. Molecular formula: C32H32O14. Mole weight: 640.59.
Cheilanthifoline
Cheilanthifoline is an alkaloid isolated from rhizomes of Sinomenium acutum with anti-osteoclastogenic property. Alternative Names: (S)-Cheilanthifoline; (6aS)-6,6a,11,14-Tetrahydro-8-methoxy-12H-benzo[a]-1,3-benzodioxolo[4,5-g]quinolizim-9-ol; (6aS)-9-methoxy-6,11,12,14-tetrahydro-2H,6aH-[1,3]dioxolo[4,5-h]isoquino[2,1-b]isoquinolin-8-ol. Grades: >98%. CAS No. 483-44-3. Molecular formula: C19H19NO4. Mole weight: 325.264.
Cheimonophyllal
It is produced by the strain of Cheimonophyllum candidissiumun sing. It has nematode killing, cytotoxicity (L1210, HL60, BHK21) and weak antifungal bacterial activity. CAS No. 160299-95-6. Molecular formula: C14H20O5. Mole weight: 268.30.
Cheimonophyllon A
It is produced by the strain of Cheimonophyllum candidissiumun sing. It has nematode killing, cytotoxicity (L1210, HL60, BHK21) and weak antifungal bacterial activity. Molecular formula: C15H22O4. Mole weight: 266.33.
Cheimonophyllon E
It is produced by the strain of Cheimonophyllum candidissiumun sing. It has nematode killing, cytotoxicity (L1210, HL60, BHK21) and weak antifungal bacterial activity. CAS No. 160299-94-5. Molecular formula: C15H24O4. Mole weight: 268.30.
Chelerythrine chloride
Chelerythrine is a cell-permeable inhibitor of protein kinase C (IC50 = 660 nM) with a wide range of biological activities. Alternative Names: Broussonpapyrine Chloride. Grades: >98%. CAS No. 3895-92-9. Molecular formula: C21H19NO4. Mole weight: 383.82.
Chelocardin
Chelocardin is produced by the strain of Nocardia sulphurea M-319. It has anti-gram-positive and negative bacterial activity, and is partially cross-resistant to tetracycline. Alternative Names: Cetocycline; 2-Decarboxamido-2-acetyl-4-desdimethylamino-4-amino-9-methyl-5a,6-anhydrotetracycline. Grades: 95%. CAS No. 29144-42-1. Molecular formula: C22H21NO7. Mole weight: 411.41.
Chevalone C
Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus and E. faecium in a disc diffusion assay when used at a concentration of 15 μg / disc. It also induces cell death in HCT116 colorectal carcinoma cells. Alternative Names: NCGC00380981-01; (2S,4aR,4bR,6aS,12aS,12bR,14aR)-2-(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one. Grades: ≥95%. CAS No. 1318025-77-2. Molecular formula: C28H40O5. Mole weight: 456.61.
Chicamycin A
Chicamycin A is produced by the strain of Streptomyces albus J576-99. It has anti-tumor activity and weak anti-gram-positive bacteria activity. Alternative Names: 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2,8-dihydroxy-7,11-dimethoxy-, (2S-(2-alpha,11-alpha,11b-beta))-; BRN 5763463. CAS No. 89675-37-6. Molecular formula: C14H18N2O5. Mole weight: 294.30.
Chicamycin B
Chicamycin B is produced by the strain of Streptomyces albus J576-99. It has anti-tumor activity and weak anti-gram-positive bacteria activity. Alternative Names: 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,11a-tetrahydro-2,8-dihydroxy-7-methoxy-, (2S-trans)-. CAS No. 89675-39-8. Molecular formula: C13H14N2O4. Mole weight: 262.26.
Chicoric acid
Chicoric acid is an antiviral substance. Uses: Antiviral. Alternative Names: Chicoric; (2R,3R)-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]butanedioic acid; (2R,3R)-2-O,3-O-Bis[3-(3,4-dihydroxyphenyl)acryloyl]tartaric acid; [2R,3R,(-)]-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]butanedioic acid; 2-O,3-O-Bis[3-(3,4-dihydroxyphenyl)propenoyl]-L-tartaric acid; Butanedioic acid, 2,3-bis((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-, (R-(R*,R*))-. Grades: ≥95%. CAS No. 6537-80-0. Molecular formula: C22H18O12. Mole weight: 474.37.
Chimeramycin A
Chimeramycin A is produced by the strain of Streptomyces ambofaciens. It has anti-gram-positive bacterial and mycoplasma activities. Grades: >98%. CAS No. 87084-47-7. Molecular formula: C48H82N2O14. Mole weight: 911.17.
Chimeramycin B
Chimeramycin B is produced by the strain of Streptomyces ambofaciens. It has anti-gram-positive bacterial and mycoplasma activities. Molecular formula: C46H80N2O13. Mole weight: 869.13.
Chimonanthine
Chimonanthine is an alkaloid isolated from the flower buds of Chimonanthus praecox. Alternative Names: 1-Demethylcalycanthidine; (-)-Chimonanthine; (3aS,8bS)-8b-[(3aS,8bS)-3-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-8b-yl]-3-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-b]indole. Grades: >98%. CAS No. 5545-89-1. Molecular formula: C22H26N4. Mole weight: 346.478.
Chitinovorin A
Chitinovorin A is produced by the strain of Flavobacerium chitinovorum PB-5016 and PB-5246. Molecular formula: C26H41N9O11S. Mole weight: 687.73.
Chitinovorin B
Chitinovorin B is produced by the strain of Flavobacerium chitinovorum PB-5016 and PB-5246. Alternative Names: L-Alaninamide, L-alanyl-N-(4-((7-((5-amino-5-carboxy-1-oxopentyl)amino)-2-carboxy-7-(formylamino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methoxy)-1-(3-((aminoiminomethyl)amino)propyl)-2-hydroxy-4-oxobutyl)-, (6R-(3(1S*,2R*),6alpha,7beta(R*)))-. Grades: >98%. CAS No. 95722-76-2. Molecular formula: C29H46N10O12S. Mole weight: 758.80.
Chitinovorin C
Chitinovorin C is produced by the strain of Flavobacerium chitinovorum PB-5016 and PB-5246. It has weak anti-gram-negative bacterial activity. Alternative Names: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((5-amino-5-carboxy-1-oxopentyl)amino)-7-(formylamino)-3-(hydroxymethyl)-8-oxo-, (6R-(6alpha,7beta(R*)))-; 7-[(5-Amino-5-carboxy-1-hydroxypentylidene)amino]-3-(hydroxymethyl)-7-[(hydroxymethylidene)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS No. 95230-98-1. Molecular formula: C15H20N4O8S. Mole weight: 416.41.