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Corynecandin
It is produced by the strain of Coryneum modonium AB 2020T-223. It is a glycolipid antibiotic with antifungal activity. The antifungal spectrum and antifungal activity are similar to Papulacandin. Alternative Names: D-Glucitol, 1,5-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-((2E,4Z)-1-oxo-2,4-decadienyl)-beta-D-galactopyranosyl)-, 3-((2E,4E)-7-hydroxy-2,8-dimethyl-2,4-decadienoate)-. CAS No. 199169-60-3. Molecular formula: C41H60O16. Mole weight: 808.90.
Corynecin ?
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: N-[(1R,2R)-1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]acetamide. Grades: >99% by HPLC. CAS No. 40958-11-0. Molecular formula: C13H16N2O6. Mole weight: 296.28.
Corynecin I
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; D-threo-2-Acetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2-Acetamido-1-p-nitrophenyl-1,3-propanediol; n-acetyl-p-nitrophenylserinol. Grades: >99% by HPLC. CAS No. 4423-58-9. Molecular formula: C11H14N2O5. Mole weight: 254.24.
Corynecin II
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: D-threo-1-p-Nitrophenyl-2-propionamido-1,3-propanediol; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]propanamide; d-threo-2-(Propionamido)-1-(p-nitrophenyl)-1,3-propanediol. Grades: >99% by HPLC. CAS No. 35098-52-3. Molecular formula: C12H16N2O5. Mole weight: 268.27.
Corynecin III
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: Methamphenicol; dimethylamphenicol; N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxy-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; d-threo-2-Isobutyramido-1-(p-nitrophenyl)-1,3-propanediol; N-[β-Hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-2-methyl-D-threo-propionamide. Grades: >99% by HPLC. CAS No. 18048-95-8. Molecular formula: C13H18N2O5. Mole weight: 282.29.
Corynecin V
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: [R-(R*,R*)]-N-[1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]-propanamide. Grades: >99% by HPLC. CAS No. 40958-12-1. Molecular formula: C14H18N2O6. Mole weight: 310.30.
Cosmomycin C
It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It has anti-tumor and gram-positive bacteria activity. It can inhibit the growth of P388 murine lymphocytic leukemia cells. Alternative Names: Antibiotic A-447B; (3''S)-3''-Hydroxycytorhodin A; 3B-Hydroxycytorhodin A; A-447B; β-Rhodomycin S2; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-7-[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-,(7R,8R,10S)-. CAS No. 55945-22-7. Molecular formula: C60H88N2O21. Mole weight: 1173.34.
Cosmomycin D
It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It has anti-tumor activity. It can inhibit the growth of P388 murine lymphocytic leukemia cells. Alternative Names: (3''S,3'''''S)-3'',3'''''-Dihydroxycytorhodin A; 1-Deoxyobelmycin D; 3B,3E-Dihydroxycytorhodin A; A-447A; Antibiotic A-447A; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R,8R,10S)-. CAS No. 95676-81-6. Molecular formula: C60H88N2O22. Mole weight: 1189.34.
Cotrimoxazole
Cotrimoxazole is a fixed antibiotic composed of trimethoprim and sulfamethoxazole. It blocks the synthesis of nucleotides to inhibit cellular metabolism in bacteria. Alternative Names: CO-Trimoxazole; Trimosulfa; Trimethoprimsulfa; Trimforte; Sulfamethoxazole-trimethoprim. CAS No. 8064-90-2. Molecular formula: C24H29N7O6S. Mole weight: 543.59.
Cotylenin F
It is produced by the strain of Cladosporium sp. It has the function of plant growth regulation. CAS No. 58045-03-7. Molecular formula: C33H54O11. Mole weight: 626.77.
Coumamidine γ1
It is produced by the strain of Saccharopolyspora sp. AB 1167L-65. It is a kind of alkaline water-soluble sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa. Alternative Names: Coumamidine gamma1; Coumamidine gamma(1). CAS No. 121634-35-3. Molecular formula: C33H49N13O13. Mole weight: 835.82.
Coumamidine γ2
It is produced by the strain of Saccharopolyspora sp. AB 1167L-65. It is a kind of alkaline water-soluble sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa. Alternative Names: Coumamidine gamma2; Coumamidine gamma(2). CAS No. 121634-34-2. Molecular formula: C33H49N13O13. Mole weight: 835.82.
CP-120509
It is produced by the strain of Actinomadura roseorufa 263606. CP-120509 has anti-gram-positive bacteria, spirochete and spirochete activity, and also has a good anti-coccidiosis effect caused by Eimeria acervulina, E. tenella. Molecular formula: C45H76O17. Mole weight: 889.07.
CP-225917
CP-225917 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. Molecular formula: C31H38O10. Mole weight: 570.63.
CP-263114
CP-263114 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. CAS No. 186700-09-4. Molecular formula: C31H36O9. Mole weight: 552.61.
CP-35587
CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria. Alternative Names: Benzeneacetamide, alpha-amino-N-(3,3-dimethyl-7-oxo-2-(1H-tetrazol-5-yl)-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-4-hydroxy-, (2S-(2alpha,5alpha,6beta))-. CAS No. 57089-17-5. Molecular formula: C16H19N7O3S. Mole weight: 389.43.
CP 412065
It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L. Alternative Names: Antibiotic CP 412065. Molecular formula: C25H34O6. Mole weight: 430.53.
CP-82009
CP-82009 is a polyether antibiotic originally isolated from Actinomadura sp. It shows strong resistance to chicken coccidiosis, and also has anti-gram-positive bacteria and spirochetes activity. Molecular formula: C49H84O17. Mole weight: 945.18.
CP 91243
CP 91243 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis. CAS No. 135179-21-4. Molecular formula: C50H84O18. Mole weight: 973.19.
CP 91244
CP 91244 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis. Alternative Names: Semduramicin, 5-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-, (5(2S,5S,6R))-. CAS No. 135215-73-5. Molecular formula: C51H86O18. Mole weight: 987.21.
CPI-444
CPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications. Alternative Names: (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine; CPI-444; CPI 444; CPI444; V81444; V-81444; V 81444. CAS No. 1202402-40-1. Molecular formula: C20H21N7O3. Mole weight: 407.17.
Cremeomycin
It is produced by the strain of Streptomyces cremeus. It has anti-gram-positive bacteria, negative bacteria, fungi (weak) activity, and has the effect of inhibiting the leukemic cell L-1210 (IC50 is 1.5 μg/mL). Alternative Names: Antibiotic U-23643. Molecular formula: C8H6N2O4. Mole weight: 194.14.
Cremimycin
It is produced by the strain of Streptomyces sp. MJ635-86F6. It has anti-gram-positive bacteria activity including methicillin-resistant staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. It showed cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro. Alternative Names: Cremimycin (antibiotic); Cyclopent(I)azacyclononadecene-7,11,17(8H,12H,19H)-trione,9,10,13,14,15,16,20,20a-octahydro-19-((2,6-dideoxy-3-O-methylhexopyranosyl)oxy)-15,18-dihydroxy-9-hexyl-2-methyl-. CAS No. 182285-29-6. Molecular formula: C35H53NO9. Mole weight: 631.79.
Crinipellin A
It is produced by the strain of Crinipellis stipitaria. It has anti-gram-positive bacteria and Aldrin ascites carcinoma activity. Alternative Names: (1R,3R,6S,8R,9S,11R,12R,13R)-8-hydroxy-7a,9a-dimethyl-3-methylidene-7-(propan-2-yl)hexahydro-1aH,5H-pentaleno[6a',1':5,6]pentaleno[1,6a-b]oxirene-2,9(3H,9aH)-dione. CAS No. 97294-60-5. Molecular formula: C20H26O4. Mole weight: 330.42.
Crinipellin B
It is produced by the strain of Crinipellis stipitaria. It has anti-gram-positive bacteria and Aldrin ascites carcinoma activity. Alternative Names: (1aS,3aR,4aS,7R,7aR,9R,9aR,9bR)-9-hydroxy-7-isopropyl-7a,9a-dimethyl-3-methyleneoctahydro-3H,8H-pentaleno[6a',1':5,6]pentaleno[1,6a-b]oxirene-2,8(1aH)-dione. CAS No. 97294-61-6. Molecular formula: C20H26O4. Mole weight: 330.42.
Crisamicin A
It is produced by the strain of Micromonospora purpureochromogenes subsp. lalotolerans. It only has activity against gram-positive bacteria. The activity of samicin C is stronger than Crisamicin A. Alternative Names: (3aS)-5β,5'β-Dimethyl-10,10'-dihydroxy-3,3',3aβ,3'aβ,5,5',6,6',11,11',11bβ,11'bβ-dodecahydro-8,8'-bi[2H-furo[3,2-b]naphtho[2,3-d]pyran]-2,2',6,6',11,11'-hexaone; (3aS,3'aS,5S,5'S,11bS,11'bS)-3,3',3a,3'a,5,5',11b,11'b-Octahydro-10,10'-dihydroxy-5,5'-dimethyl-8,8'-bi[2H-furo[3,2-b]naphtho[2,3-d]pyran]-2,2',6,6',11,11'-hexone; CRS-A; (8,8'-Bi-2H-furo(3,2-b)naphtho(2,3-d)pyran)-2,2',6,6'11,11'-hexone,3,3',3a,3'a,5,5',11b,11'b-octahydro-10,10'-dihydroxy-5,5'-dimethyl-, (3aS-(3aalpha,5alpha,8(3aR*,5R*,11bR*),11balpha))-. CAS No. 95828-47-0. Molecular formula: C32H22O12. Mole weight: 598.51.
Crisamicin C
It is produced by the strain of Micromonospora purpureochromogenes subsp. lalotolerans. It only has activity against gram-positive bacteria. The activity of samicin C is stronger than Crisamicin A. Alternative Names: CRS-C. CAS No. 100630-79-3. Molecular formula: C32H22O13. Mole weight: 614.51.
Cristatic acid
It is produced by the strain of Albaterllus cristatus. It can resist bacillus, tumor and hemolysis. Alternative Names: NSC338268; NSC 338268; Cristatic acid-1. CAS No. 80557-13-7. Molecular formula: C23H28O5. Mole weight: 384.46.
CRM-51005
It is a phospholipase C (PLC) inhibitor originally isolated from fungal MT51005. Alternative Names: Benzaldehyde, 3-ethyl-2,4-dihydroxy-6-((1E)-1-methyl-1-pentenyl)-; Benzaldehyde, 3-ethyl-2,4-dihydroxy-6-(1-methyl-1-pentenyl)-, (E)-; 3-ethyl-6-[(E)-hex-2-en-2-yl]-2,4-dihydroxybenzaldehyde. CAS No. 203051-01-8. Molecular formula: C15H20O3. Mole weight: 248.32.
CRM646-A
It is originally isolated from Acremonium sp. MT70646. CRM646-A had a strong inhibitory effect on the movement of B16-H10 melanoma cells with IC50 of 15 μmol/L. Alternative Names: CRM-646-A; CHEMBL3347523. Molecular formula: C36H50O13. Mole weight: 690.77.
CRM646-B
It is originally isolated from Acremonium sp. MT70646. CRM646-B had a strong inhibitory effect on the movement of B16-H10 melanoma cells with IC50 of 30 μmol/L. Alternative Names: CRM-646-B; 4-[(4-Carboxy-3-hydroxy-5-methylphenoxy)carbonyl]-3-hydroxy-5-pentadecylphenyl methyl β-D-glucopyranosiduronate. Molecular formula: C37H52O13. Mole weight: 704.80.
Crocacin A
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Alternative Names: (+)-CrocainA; [(2Z,5Z)-6-((6S,7S,8S,9S)-(2E,4E,10E)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenyl-undeca-2,4,10-trienoylamino)-hexa-2,5-dienoylamino]-acetic acid, methyl ester; Methyl 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetate. CAS No. 157698-34-5. Molecular formula: C31H42N2O6. Mole weight: 538.67.
Crocacin B
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Alternative Names: [[(2Z,5Z)-6-[[(2E,4E,6S,7S,8R,9S,10E)-7,9-Dimethoxy-3,6,8-trimethyl-1-oxo-11-phenyl-2,4,10-undecatrienyl]amino]-1-oxo-2,5-hexadienyl]amino]acetic acid; 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetic acid. CAS No. 237425-37-5. Molecular formula: C30H40N2O6. Mole weight: 524.65.
Crocacin C
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Alternative Names: (+)-Crocacin C; (2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienamide; 7,9-dimethoxy-3,6,8-trimethyl-11-phenyl-(2E,4E,6S,7S,8R,9S,10E)-2,4,10-undecatrienamide. CAS No. 237425-38-6. Molecular formula: C22H31NO3. Mole weight: 357.49.
Crocacin D
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Alternative Names: (+)-Crocacin D. CAS No. 237425-39-7. Molecular formula: C31H44N2O6. Mole weight: 540.69.
Crotocin
It is produced by the strain of Cephalosporium crotocinigenum. It has the fungal activity of anti-cryptococcus neoforme, candida albicans, Tinea trichoderma of brewer's yeast, and can be inactivated by blood. Alternative Names: Antibiotic T; 4-Isocrotonyloxy-7,8-epoxyscirp-9-ene; Trichothec-9-en-4-beta-ol, 7-beta,8-beta:12,13-diepoxy-, crotonate, (Z)-; Trichothec-9-en-4-ol, 7,8:12,13-diepoxy-, (2Z)-2-butenoate, (4beta,7beta,8beta)-. CAS No. 21284-11-7. Molecular formula: C19H24O5. Mole weight: 332.39.
Cryptochlorophaeic acid
Cryptochlorophaeic acid is obtained from Cladonia cryptochlorophaea Asahina. CAS No. 2948-7-4. Molecular formula: C25H32O8. Mole weight: 460.52.
Cryptophycin 1
Cryptophycin 1, produced by Nostoc sp. GSV 224, is a potent cytotoxic anti-microtubule agent. Cryptophycin 1 can induce cell apoptosis, and has anti-tumor activity and excellent anti-proliferation ability. Alternative Names: Cryptophycin A; Cryptophycin; Cyclo[(2R)-2-methyl-β-alanyl-(2S)-2-hydroxy-4-methylpentanoyl-(2E,5S,6S)-5-hydroxy-6-[(2R,3R)-3-phenyl-2-oxiranyl]-2-heptenoyl-3-chloro-O-methyl-D-tyrosyl]; 1,4-Dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, 10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-16-[(1S)-1-[(2R,3R)-3-phenyloxiranyl]ethyl]-, (3S,6R,10R,13E,16S)-; (3S,6R,10R,13E,16S)-10-(3-Chloro-4-methoxybenzyl)-3-isobutyl-6-methyl-16-{(1S)-1-[(2R,3R)-3-phenyl-2-oxiranyl]ethyl}-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone. Grades: ≥95%. CAS No. 124689-65-2. Molecular formula: C35H43ClN2O8. Mole weight: 655.19.
Cryptoporic acid A
It is produced by the strain of Cryptoporus volvatus. Alternative Names: (2R,3S)-3-Methoxycarbonyl-2-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-ylmethoxy)-pentanedioic acid 1-methyl ester. CAS No. 113592-87-3. Molecular formula: C22H36O7. Mole weight: 412.52.
Cryptoporic acid D
It is produced by the strain of Cryptoporus volvatus. Alternative Names: 7,11,24,28-Tetraoxapentacyclo(28.4.0.0(5,34).0(13,18).0(17,22))tetratriacontane-9,26-diacetic acid,8,25-bis(methoxycarbonyl)-13,17,30,34-tetramethyl-4,21-bis(methylene)-10,27-dioxo-,(1R-(1R*,5S*,8R*,9S*,13R*,17S*,18R*,22S*,25R*,26S*,30R*,34S*))-. CAS No. 119979-95-2. Molecular formula: C44H64O14. Mole weight: 816.97.
Cryptoporic acid E
It is produced by the strain of Cryptoporus volvatus. Alternative Names: (3S,4R)-3-((((1R,4aS,5S,8aR)-5-((((2R,3S)-3-(carboxymethyl)-1,4-dimethoxy-1,4-dioxobutan-2-yl)oxy)methyl)-1,4a-dimethyl-6-methylenedecahydronaphthalen-1-yl)methoxy)carbonyl)-4-(((1S,4aR,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)methoxy)-5-methoxy-5-oxopentanoic acid. CAS No. 120001-10-7. Molecular formula: C45H68O15. Mole weight: 849.01.
Cryptosporiopsin
It is produced by the strain of Cryptosporiopsis sp. and Sporormia affinis. It has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. It also has certain activity against gram-positive bacteria and negative bacteria. Alternative Names: (+)-Cryptosporiopsin; 2-Cyclopentene-1-carboxylic acid, 5-dichloro-1-hydroxy-4-oxo-2-propenyl-, methyl ester, (E)-(1S,5S)-(+)-. CAS No. 25707-30-6. Molecular formula: C10H10Cl2O4. Mole weight: 265.09.
Cryptosporiopsin A
It is produced by the strain of Cryptosporiopsis sp. and Sporormia affinis. It has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. It also has certain activity to gram-positive bacteria and negative bacteria. Alternative Names: (3R,9E)-13-Chloro-4,5,7,8-tetrahydro-14-hydroxy-16-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,6,11(3H,12H)-trione. CAS No. 1402990-52-6. Molecular formula: C19H21ClO6. Mole weight: 380.82.
Cryptosporioptide E
A bioactive polyketide produced by an endophytic fungus Cryptosporiopsis sp.
Cryptothamnolic acid
Cryptothamnolic acid. Alternative Names: 3-[(3-Formyl-2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-4,6-dihydroxy-2,5-dimethylbenzoic acid. CAS No. 258862-16-7. Molecular formula: C19H18O9. Mole weight: 390.34.
Cucurbitacin A
Cucurbitacin A is a triterpenoid sterol isolated from rhizomes of Hemsleya amabilis Diels. Alternative Names: Cucurbitacin A; 6040-19-3; UNII-83859; MTO77NSC94743; CHEBI:3940. Grades: >98%. CAS No. 6040-19-3. Molecular formula: C32H46O9. Mole weight: 574.711.
Cuevaene A
It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. Alternative Names: (2E,4Z,6E)-7-(8-hydroxy-1,2,3,4-tetrahydrodibenzo[b,d]furan-1-yl)-4-methoxy-6-methylhepta-2,4,6-trienoic acid. CAS No. 1246172-08-6. Molecular formula: C21H22O5. Mole weight: 354.40.
Cuevaene B
It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. CAS No. 274684-11-6. Molecular formula: C21H24O7. Mole weight: 388.41.
Culpin
It is produced by the strain of Preussia sp. It has weak antibacterial and antifungal activity. Alternative Names: 2-(3-Methyl-2-butenyl)-5-(3-methyl-3-buten-1-ynyl)-1,4-benzenediol. Grades: ≥ 98%. CAS No. 125213-21-0. Molecular formula: C16H18O2. Mole weight: 242.31.
Curromycin A
It is produced by the strain of Streptomyces hygroscipicus 358AV2. It has antibacterial activity against gram-positive bacteria such as Bacillus subtilis. It can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells. Alternative Names: Triedimycin A; 4,6,8-Decatrienamide, 3-hydroxy-N-(6-hydroxy-9-(8-hydroxy-1-(methoxymethyl)-5,7-dimethyl-3,6-dioxo-2-oxa-5-azaspiro(3.4)oct-8-yl)-9-methoxy-7-methyl-2,4-nonadienyl-2,2,4-trimethyl-10-(2-methyl-5-oxazolyl)-. CAS No. 97412-76-5. Molecular formula: C38H55N3O10. Mole weight: 713.87.
Curromycin B
It is produced by the strain of Streptomyces hygroscipicus 358AV2. It has antibacterial activity against gram-positive bacteria such as Bacillus subtilis. It can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells. Alternative Names: Triedimycin B; 4,6,8-Decatrienamide, 3-hydroxy-N-(6-hydroxy-9-(8-hydroxy-1,5,7-trimethyl-3,6-dioxo-2-oxa-5-azaspiro(3.4)oct-8-yl)-9-methoxy-7-methyl-2,4-nonadienyl-2,2,4-trimethyl-10-(2-methyl-5-oxazolyl)-; 30-Demethoxycurromycin A. CAS No. 97412-77-6. Molecular formula: C37H53N3O9. Mole weight: 683.84.
Curtisian A
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.15 μg/mL. Alternative Names: 3',5',6'-tris(acetyloxy)-4,4''-dihydroxy-1,1':4',1''-terphenyl-2'-yl benzoate; 2',3',6'-Triacetoxy-5'-(benzoyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C31H24O10. Mole weight: 556.52.
Curtisian B
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.17 μg/mL. Alternative Names: 3',5',6'-tris(acetyloxy)-4,4''-dihydroxy-1,1':4',1''-terphenyl-2'-yl 3-phenylpropanoate; 2',3',6'-Triacetoxy-5'-(phenethylcarbonyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C33H28O10. Mole weight: 584.57.
Curtisian C
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.24 μg/mL. Alternative Names: [4-acetyloxy-2,5-bis(3-acetyloxybutanoyloxy)-3,6-bis(4-hydroxyphenyl)phenyl] 3-hydroxybutanoate. Molecular formula: C36H38O15. Mole weight: 710.68.
Curtisian D
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.24 μg/mL. Alternative Names: 5',6'-bis(acetyloxy)-4,4''-dihydroxy-3'-[(3-phenylpropanoyl)oxy]-1,1':4',1''-terphenyl-2'-yl 3-hydroxybutanoate; 5',6'-Diacetoxy-2'-(3-phenylpropanoyloxy)-3'-(3-hydroxybutanoyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C35H32O11. Mole weight: 628.62.
Curvularin
It is produced by the strain of Curvularia sp., Penicillum gilmanii and Pen. citroviride. It strongly inhibits cell division and is a toxin harmful to plants. Alternative Names: S-Curvularin; NSC 166071; 11,13-Dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione; 2H-3-Benzoxacyclododecin-2,4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)-. Grades: >99% by HPLC. CAS No. 10140-70-2. Molecular formula: C16H20O5. Mole weight: 292.33.
Curvularol
It is produced by the strain of Curvularia sp. RK97-F166. It has weak anti-fungal activity and no anti-bacterial effect. Curvularol of 150 ng/mL inhibits the cell cycle progression of NRK in normal rats at G1 stage. Curvularol of 100 ng/mL can restore the morphology of SRC TS-deformed NRK cells. Like Cycloheximide, it inhibits protein synthesis. Alternative Names: (2S,4S,5S,5aR,9aS,10S)-5,5a,8-trimethyl-5a,6,7,9a-tetrahydro-5H-spiro[2,5-methano[1]benzoxepine-4,2'-oxirane]-2,10(3H)-diol. CAS No. 339293-67-3. Molecular formula: C15H22O4. Mole weight: 266.33.
Curvulic acid
It is produced by the strain of Curvularia siddiqui, Penicillum janthynellum C-268. It has weak activity against gram-positive and negative bacteria. Para-aminobenzoic acid can antagonize its action. Alternative Names: 2-Acetyl-3,5-dihydroxy-4-methoxy-phenylessigsaeure; 2-Acetyl-3,5-dihydroxy-4-methoxybenzeneacetic acid. CAS No. 652-55-1. Molecular formula: C11H12O6. Mole weight: 240.21.
Curvulinic acid
Curvulinic acid is a phytotoxin isolated from C. siddiqui. Grades: >95% by HPLC. CAS No. 19053-94-2. Molecular formula: C10H10O5. Mole weight: 210.18.
CV-1
CV-1 is an antibiotic produced by Streptomyces sp. CO-1. It has anti-Escherichia coli activity in combination with spiramycin, and its mechanism is to inhibit lipopolysaccharide synthesis. Alternative Names: 1,2-Diamino-1,2-N,N'-carbonyl-1,2-dideoxyglucose hydrate. CAS No. 108351-34-4. Molecular formula: C7H14N2O6. Mole weight: 222.20.
Cyathin A3
It is produced by the strain of Cyathus helenae, C. africanus. It has weak activity against gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model). CAS No. 38598-35-5. Molecular formula: C20H30O3. Mole weight: 318.45.
Cyathin A4
It is produced by the strain of Cyathus helenae, C. africanus. It has weak activity against gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model). Molecular formula: C20H30O4. Mole weight: 334.45.
Cyclacidin
It is produced by the strain of Streptomyces capoamus 4670-IA 37. It has anti-individual gram-positive bacteria (subtilis, Gambosia occidentalis) activity, and has inhibitory effect on sarcoma 180 and so on. Alternative Names: Bisanhydrorutilantinone; pi-Pyrromycinone; Bisanhydropyrromycinone; eta-Pyrromycinone; 1-Naphthacenecarboxylic acid, 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-, methyl ester; Methyl 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-1-naphthacenecarboxylate; ciclacidine. CAS No. 749-18-8. Molecular formula: C22H16O7. Mole weight: 392.36.
Cyclipostin A
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C23H41O7P. Mole weight: 460.54.
Cyclipostin P
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 30 nmol/L against HSL in rats. Alternative Names: (1beta)-4beta-(Hexadecyloxy)-6-methyl-8-oxo-3,5,9-trioxa-4-phosphabicyclo[5.3.0]deca-6-ene 4-oxide; (6S)-6alpha-(Hexadecyloxy)-8-methyl-3,3abeta-dihydro-1H,4H,6H-2,5,7-trioxa-6-phosphaazulene-1-one 6-oxide. Molecular formula: C23H41O6P. Mole weight: 444.54.
Cyclipostin P2
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 40 nmol/L against HSL in rats. Molecular formula: C23H41O6P. Mole weight: 444.54.
Cyclipostin S
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C24H43O6P. Mole weight: 458.57.
Cyclochlorotine
It is produced by the strain of Penicillium islandicum. It can accelerate the degradation of glycogen and make the Liver glycogen particles disappear. Alternative Names: Chloropeptide; Cyclic(L-3-phenyl-beta-alanyl-L-seryl-(3S-cis)-3,4-dichloro-L-prolyl-L-alpha-aminobutyryl-L-seryl). Grades: ≥ 98%. CAS No. 12663-46-6. Molecular formula: C24H31Cl2N5O7. Mole weight: 572.44.
Cyclo(delta-Ala-L-Val)
It is a diketopiperazine formed by the fusion of δ-alanine and valine and is a secondary metabolite of fungi and bacteria. It can activate N-acylhomoserine lactones (AHLs) and can also activate or antagonize other LuxR-based quorum-sensing systems. Alternative Names: 3-Methylene-6S-(1-methylethyl)-2,5-piperazinedione; 2,5-Piperazinedione, 3-methylene-6-(1-methylethyl)-, (S)-; Cyclo(Δ-Ala-L-Val). Grades: >98% by HPLC. CAS No. 25516-00-1. Molecular formula: C8H12N2O2. Mole weight: 168.19.
Cyclo (D-Pro-L-Val)
It is produced by the strain of Aspergillus sp. F70609. It can inhibit β-glucoside enzyme activity with IC50 of 75 μg/mL. It has no or only weak inhibitory effect on other glycosidases. Alternative Names: (3S,8aR)-3-isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aR)-. CAS No. 156617-55-9. Molecular formula: C10H16N2O2. Mole weight: 196.25.