BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cycloechinulin | An unusual diketopiperazine isolated from aspergillus ochraceus. It exhibits insecticidal activity against the lepidopteran crop pest, helicoverpa zea. It is used as a secondary metabolite standard for polyphasic taxonomy in aspergillus. Alternative Names: (3S)-2,3,8,9-Tetrahydro-11-methoxy-3,8,8-trimethylpyrazino[1',2':1,2]azocino[5,4-b]indole-1,4-dione; (S)-2,3,8,9-Tetrahydro-11-methoxy-3,8,8-trimethyl-pyrazino[1',2':1,2]azocino[5,4-b]indole-1,4-dione. Grades: >99% by HPLC. CAS No. 143086-29-7. Molecular formula: C20H21N3O3. Mole weight: 351.40. |  |
| Cycloepoxydon | It is produced by the strain of Duteromycete 45-93. It can inhibit TPA induced expression of k gene binding nuclear factor (NF-KB) and activator protein-1 (APT-1) mediated secreted alkaline phosphatase (SEAP), with IC50 of 4.2-9.4 mol/L and 4.2-9.4 mol/L, respectively. Molecular formula: C12H16O5. Mole weight: 240.25. | |
| Cyclogregatin | It is produced by the strain of Aspergillus panamensis. It has anti-bacterial and fungal activity, but its antibacterial and fungal activity is lower than polymyxin A. It inhibits airy ascites carcinoma with MIC of 10 μg/mL (Gregatin A is 2 μg/mL). Alternative Names: 4H-Furo(2,3-b)pyran-3,4(2H)-dione, 2-(1,3-hexadienyl)-5,6-dihydro-2,6-dimethyl-. CAS No. 120167-25-1. Molecular formula: C15H18O4. Mole weight: 262.30. | |
| Cycloheptamycin | It is produced by the strain of Streptomyces sp. MZ 1158. It has anti-gram-positive bacterial and mycobacterium activity. CAS No. 30270-78-1. Molecular formula: C48H68N8O12. Mole weight: 949.10. | |
| cyclo(L-Ala-L-Leu) | Cyclo(L-Ala-L-Leu) is a cyclic diketopiperazine found in fungi and bacteria. It has antiviral activity. Grades: >95% by HPLC. CAS No. 24676-83-3. Molecular formula: C9H16N2O2. Mole weight: 184.24. | |
| Cyclo(L-Ala-L-Pro) | Cyclo(L-Ala-L-Pro) is a cyclodipeptide found in Phellinus igniarius. Cyclo(L-Ala-L-Pro) exhibits an inhibitory effect on Aflatoxin Production of Aspergillus flavus. Alternative Names: Cyclo(alanylprolyl); cyclo(prolylalanyl); Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (3S,8aS)-; Cyclo-(L-alanine-L-proline); cyclo(Pro-Ala); L-Prolyl-L-alaninediketopiperazine. Grades: 98%. CAS No. 36357-32-1. Molecular formula: C8H12N2O2. Mole weight: 168.19. | |
| Cycloleucomelone | It is produced by the strain of Boletopsis leucomelaena. Alternative Names: Cycloleucomelon; 2,7,8-Trihydroxy-3-(4-hydroxy-phenyl)-dibenzofuran-1,4-dione. CAS No. 112209-48-0. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Cyclo(L-Leu-L-Trp) | Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria and fungi, and it also inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 μM). Alternative Names: 3S-(1H-indol-3-ylmethyl)-6S-(2-methylpropyl)-2,5-piperazinedione; Cyclo(L-leucyl-L-tryptophyl); Cyclo(leu-trp); Cyclo(L-Trp-L-Leu); 2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(2-methylpropyl)-, (3S-cis)-. Grades: ≥95%. CAS No. 15136-34-2. Molecular formula: C17H21N3O2. Mole weight: 299.37. | |
| Cyclo(L-Leu-trans-4-hydroxy-L-Pro) | Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural compound isolated from Phellinus igniarius. It is a plant growth regulator. Alternative Names: Cyclo(L-leucyl-trans-4-hydroxy-L-proline); Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(2-methylpropyl)-, (3S,7R,8aS)-; L-hydroxyprolyl-L-leucine anhydride; cyclo[L-(4-hydroxyprolinyl)-L-leucine]; 7-Hydroxygancidin W. Grades: ≥95%. CAS No. 115006-86-5. Molecular formula: C11H18N2O3. Mole weight: 226.27. | |
| Cyclo(L-phenylalanyl-trans-4-hydroxy-L-proline) | Cyclo(L-Phe-trans-4-hydroxy-L-Pro) is a cyclodipeptide from the fermentation broth of Streptomyces sp. YIM67005. It is a plant growth regulator. Alternative Names: L-Phe-trans-4-hydroxy-L-Pro; (4R)-4-Hydroxycyclo(L-Pro-L-Phe-); Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline); Cyclo[(4-hydroxyprolinyl)-L-phenylalanine]; cyclo-(L-phenylalanine-trans-4-hydroxy-L-proline). Grades: 95%. CAS No. 118477-06-8. Molecular formula: C14H16N2O3. Mole weight: 260.29. | |
| cyclo(L-Tyr-L-Val) | Cyclo(L-Tyr-L-Val) is a diketopiperazine metabolite isolated from marine actinomycetes (Nocardiopsis gilva). Alternative Names: Cyclo(Tyr-Val). Grades: >95% by HPLC. CAS No. 21754-25-6. Molecular formula: C14H18N2O3. Mole weight: 262.3. | |
| Cyclononylprodiginine | Cyclononylprodiginine is a prodigiosin antibiotic. CAS No. 34852-35-2. Molecular formula: C23H29N3O. Mole weight: 363.49. | |
| Cyclooctatin | It is produced by the strain of Sreptomyces melanosporofaciens M1614-43F2. It can inhibit the hemolysis phospholipase [EC 3.1.1.5] (Lyso-PL) activity. Terpentecin as substrates, it inhibits Lyso-PL, PL-A2, PL-C and PL-D with IC50 of 2.9 μg/mL, 65.0 μg/mL, 70.0 μg/mL and >100 μg/mL, respectively. Ki is 4.8 X 10-6 mol/L. Alternative Names: Dicyclopenta(a,d)cyclooctene-3,4-diol,1,2,3,3a,4,5,7,8,9,9a,10,10a-dodecahydro-4,9a-dimethyl-1-(hydroxymethyl)-7-(1-methylethyl)-; 1-(Hydroxymethyl)-7-isopropyl-4,9a-dimethyl-1,2,3,3a,4,5,7,8,9,9a,10,10a-dodecahydrodicyclopenta[a,d]cyclooctene-3,4-diol. CAS No. 139552-97-9. Molecular formula: C20H34O3. Mole weight: 322.49. | |
| Cyclopaldic acid | It is produced by the strain of Penicillum cyclopium var. album, Pen. cyclopium 77. Cyclopaldic acid of 2.5 μg/mL can inhibit the spore germination of Garlic botrytis spore 95%-100%. Alternative Names: 3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-1,3-dihydro-2-benzofuran-4-carbaldehyde; 1,3-Dihydro-3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-4-isobenzofurancarboxaldehyde; Cyclopaldsaeure. CAS No. 477-99-6. Molecular formula: C11H10O6. Mole weight: 238.19. | |
| Cyclopenin | It is produced by the strain of Penicillum cyclopium and Pen. corymbiferum. Cyclopenin can inhibit the growth of plants. Cyclopenin acts as an inhibitor of acetylcholinesterase (AChE). Cyclopenin also has antibacterial activity against E. coli and M. pyogenes. Alternative Names: (-)-Cyclopenine; (-)-Cyclopenin; Cyclopenine; (3S,3'R)-4-Methyl-3'-phenylspiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione; Spiro(3H-1,4-benzodiazepine-3,2'-oxirane)-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, cis-(-)-(9CI)-. Grades: ≥99%. CAS No. 20007-87-8. Molecular formula: C17H14N2O3. Mole weight: 294.30. | |
| Cyclopentanone, 2-(5-bromo-2-methoxy-4-methylphenyl)-2-methyl- | Cyclopentanone, 2-(5-bromo-2-methoxy-4-methylphenyl)-2-methyl-. Alternative Names: 2-(5-Bromo-2-methoxy-4-methylphenyl)-2-methylcyclopentanone. CAS No. 23963-91-9. Molecular formula: C14H17BrO2. Mole weight: 297.19. | |
| Cyclopeptine | A benzodiazepine metabolite produced by a number of species of penicillium. Alternative Names: (S)-cyclopeptine; (3S)-3-benzyl-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione. Grades: >99% by HPLC. CAS No. 50886-63-0. Molecular formula: C17H16N2O2. Mole weight: 280.32. | |
| Cyclophostin | It is produced by the strain of Streptomyces lavendulae NK901093. It strongly inhibits AChE activity, it inhibits the AchE of houseflies with IC50 of 7.6 X 10-10 mol/L. Alternative Names: Rac-Cyclophostin; 1H,6H-Furo(3,4-e)(1,3,2)dioxaphosphepin-6-one,8,8a-dihydro-3-methoxy-5-methyl-, 3-oxide, (3R-cis)-. CAS No. 144773-26-2. Molecular formula: C8H11O6P. Mole weight: 234.14. | |
| Cyclopiazonic acid | It is produced by the strain of Various penicillium. It's a mycotoxin and it's neurotoxic. Its toxicity is linked to its ability to specifically and reversibly inhibit sarco-endoplasmic reticulum Ca2+-ATPases. Alternative Names: (6aR,11aS,11bR)-10-Acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one. Grades: 98% (HPLC). CAS No. 18172-33-3. Molecular formula: C20H20N2O3. Mole weight: 336.38. | |
| Cyclosporin | It is produced by the strain of Polypocladiurn inflatum. It has a strong immunosuppressive action, but also has anti-inflammatory and weak antifungal effects. The mechanism of immunosuppression is the combination of cyclosporin A and cyclosporin-binding protein in T cells, which inhibits the activity of Calcineurin, and then impedes the transposition of intracellular transcription factors into the nucleus, and inhibits the interleukin-2 transcription, resulting in immunosuppression. It is mainly used for kidney transplantation, bone marrow and heart transplantation, and is one of the most important immunosuppressive agents in clinical application. Uses: Enzyme inhibitors. Alternative Names: Cyclosporins. Grades: >98%. CAS No. 79217-60-0. | |
| Cyclosporin AM 4N | Cyclosporin AM 4N is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: 9-L-Leucinecyclosporin A; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv; AM 4N; Cyclosporin A Metabolite 21; M 21; OL 21; [Leu4]cyclosporin. Grades: ≥90% by HPLC. CAS No. 89270-23-5. Molecular formula: C61H109N11O12. Mole weight: 1188.58. | |
| Cyclosporine Impurity 3 Sodium Salt | Cyclosporine Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grades: ≥90% by HPLC. Molecular formula: C7H14NO3Na. Mole weight: 183.18. | |
| Cyclosporine metabolite M17 | Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Alternative Names: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-. Grades: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61. | |
| Cyclosporin Impurity 2 | Cyclosporin Impurity 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: (2S,3R,4R,E)-3,8-dihydroxy-4-methyl-2-(methylamino)oct-6-enoic acid. Grades: ≥90% by HPLC. Molecular formula: C10H19NO4. Mole weight: 217.26. | |
| Cyclosporin Impurity 4 | Cyclosporin Impurity 4 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: 4-(2E)-2-Buten-1-yl-2,4,5-trideoxy-2-(methylamino)-L-xylonic acid; (2S,3R,4R,E)-3-Hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid; 6-Octenoic acid, 3-hydroxy-4-methyl-2-(methylamino)-, (2S,3R,4R,6E). Grades: ≥90% by HPLC. CAS No. 59865-23-5. Molecular formula: C10H19NO3. Mole weight: 201.26. | |
| Cyclosporin Impurity 6 | Cyclosporin Impurity 6 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grades: ≥90% by HPLC. CAS No. 1357559-31-3. Molecular formula: C8H15BF3N2K. Mole weight: 246.13. | |
| Cyclosporin L Related Compound 1 | Cyclosporin L Related Compound 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: (E)-(R)-2-Methyl-hex-4-enoic acid. Grades: ≥90% by HPLC. CAS No. 93553-73-2. Molecular formula: C7H12O2. Mole weight: 128.17. | |
| Cyclosporin L Related Compound 2 | Cyclosporin L Related Compound 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: (R,E)-2-methylhex-4-en-1-ol; (E)-(R)-2-Methyl-hex-4-en-1-ol; (2R,4E)-2-Methyl-4-hexen-1-ol; 4-Hexen-1-ol, 2-methyl-, (2R,4E)-. Grades: ≥90% by HPLC. CAS No. 104372-56-7. Molecular formula: C7H14O. Mole weight: 114.18. | |
| Cyclothialidine | It is produced by the strain of Streptomyces filipinensis NR 0484. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.3 μmol/L, and the reference neomycin was 1.2 μmol/L. Alternative Names: Cyclothialidine A; (2S)-2-[[(5S,8R)-5-[[(2S,3R)-1-(2-amino-3-hydroxypropanoyl)-3-hydroxypyrrolidine-2-carbonyl]amino]-13,15-dihydroxy-16-methyl-2,6-dioxo3-oxa-10-thia-7-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-8-carbonyl]amino]propanoic acid; N-[[(4R,7S)-1,3,4,5,6,7,8,10-octahydro-12,14-dihydroxy-7-[[(3R)-3-hydroxy-1-L-seryl-L-prolyl]amino]-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecin-4-yl]carbonyl]-L-alanine. CAS No. 147214-63-9. Molecular formula: C26H35N5O12S. Mole weight: 641.65. | |
| Cyclothialidine B | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-76-1. Molecular formula: C25H33N5O11S. Mole weight: 611.62. | |
| Cyclothialidine C | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 161161-54-2. Molecular formula: C26H35N5O11S. Mole weight: 625.66. | |
| Cyclothialidine D | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-78-3. Molecular formula: C24H31N5O11S. Mole weight: 597.60. | |
| Cyclothialidine E | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-79-4. Molecular formula: C25H33N5O11S. Mole weight: 611.63. | |
| Cyclothiazomycin | It is produced by the strain of Streptomyces sp. NR0516. It selectively inhibits renin activity and does not inhibit pepsin, aspartic acid, serine, mercaptan protease and metalloproteinases. In addition, it has weak antifungal activity. Alternative Names: cyclothiazomycin A; 5102-II. CAS No. 133352-26-8. Molecular formula: C59H64N18O14S7. Mole weight: 1473.71. | |
| Cyclothiocurvularin A | Cycuriocurvularin is a 12-membered macrolide isolated from Penicillium and Curvularia sp. Grades: >95% by HPLC. Molecular formula: C19H22O8S. Mole weight: 410.44. | |
| Cycloviracin B1 | Cycloviracin B1 is produced by the strain of Kibdelosporangium albatum sp. R761-7. It has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-gram-positive bacterial activity. Alternative Names: (1S,3R,8R,9S,10S,11S,12R,14R,19S,20S,21R,22S)-3-((16R)-16,22-bis(((2S,3R,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)oxy)tricosyl)-14-(14-(((2S,3R,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)oxy)-20-hydroxyhenicosyl)-9,10,11,20,21,22-hexahydroxy-2,6,13,17,23,24-hexaoxatricyclo[17.3.1.18,12]tetracosane-5,16-dione. CAS No. 142382-45-4. Molecular formula: C83H152O33. Mole weight: 1678.07. | |
| Cycloviracin B2 | Cycloviracin B2 is produced by the strain of Kibdelosporangium albatum sp. R761-7. It has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-gram-positive bacterial activity. CAS No. 142382-46-5. Molecular formula: C83H150O33. Mole weight: 1676.06. | |
| CYL-2 | CYL-2 is a cyclic tetrapeptide produced by the strain of Cylindrocladium scoparium. It has anti-bacterial activity. Alternative Names: (3s,6r,15as)-9-[(2s)-butan-2-yl]-6-(4-methoxybenzyl)-3-[6-(oxiran-2-yl)-6-oxohexyl]octahydro-2h-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3h,12h)-tetrone; Cyclo(O-methyltyrosine-L-isoleucine-L-pipecolic acid-2-amino-8-oxo-9,10-epoxydecanoic acid). CAS No. 42002-26-6. Molecular formula: C32H46N4O7. Mole weight: 598.73. | |
| Cymbimicin A | It is produced by the strain of Micromonospora sp. A92-313709. Cymbimicin A had a strong affinity with cyclosporin-binding protein, and the affinity between Cymbimicin B and cyclosporin-binding protein was about 100 times lower than that of Cymbimicin A. CAS No. 200563-97-9. Molecular formula: C59H92N4O14. Mole weight: 1053.36. | |
| Cymbimicin B | It is produced by the strain of Micromonospora sp. A92-313709. Cymbimicin B had a strong affinity with cyclosporin-binding protein, and the affinity between Cymbimicin B and cyclosporin-binding protein was about 100 times lower than that of Cymbimicin A. CAS No. 200564-07-4. Molecular formula: C58H86N2O13. Mole weight: 1019.31. | |
| Cynarin | Cynarin, phenolic compound, is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities. Cynarin is used in weight loss and lipid-lowering formulas, liver protection and anti-alcoholic drugs, etc. Alternative Names: Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-; (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid; Cinnamic acid, 3,4-dihydroxy-, 1-carboxy-4,5-dihydroxy-1,3-cyclohexylene ester; Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-; Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-4,5-dihydroxy-, [1R-(1α,3α,4α,5β)]-; Cynarine; 1,3-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid; Cinarin; Cinarine. Grades: >98%. CAS No. 30964-13-7. Molecular formula: C25H24O12. Mole weight: 516.45. | |
| Cyrmenin A | It is produced by the strain of Cystobacter armeniaca Cb a24, Archangium gephyra Ar 9944. It is a β-methoxy acrylic acid (MOA) inhibitor. Cyrmenin A inhibits NADH oxidation of bovine heart submitochondrial particles with IC50 of 27 ng/mL. The mechanism is to block the bc1 phase of electron transport in the respiratory chain. CAS No. 675150-03-5. Molecular formula: C22H34N2O5. Mole weight: 406.51. | |
| Cyrmenin B1 | It is produced by the strain of Cystobacter armeniaca Cb a24, Archangium gephyra Ar 9944. It is a β-methoxy acrylic acid (MOA) inhibitor. Cyrmenin B1 inhibits NADH oxidation of bovine heart submitochondrial particles with IC50 of 41 ng/mL. The mechanism is to block the bc1 phase of electron transport in the respiratory chain. CAS No. 675150-04-6. Molecular formula: C21H32N2O5. Mole weight: 392.49. | |
| Cyrmenin B2 | It is produced by the strain of Cystobacter armeniaca Cb a24, Archangium gephyra Ar 9944. It is a β-methoxy acrylic acid (MOA) inhibitor. Cyrmenin B2 inhibits NADH oxidation of bovine heart submitochondrial particles with IC50 of 159 ng/mL. The mechanism is to block the bc1 phase of electron transport in the respiratory chain. CAS No. 672929-30-5. Molecular formula: C21H32N2O5. Mole weight: 392.49. | |
| Cystothiazole A | It is produced by the strain of Cystobacter fuscus. It has antifungal activity. It can inhibit candida albicans, saccharomyces cerevisiae and aspergillus smoke with MIC of 0.4 μg/mL, 0.1 μg/mL and 1.6 μg/mL, respectively. It also inhibits human tumor cell, such as HPT-116 and K562 cells with MIC of 130 ng/mL and 110 ng/mL, respectively. It has no anti-bacterial effect. Alternative Names: Melithiazole E; (+)-cystothiazole A; methyl (2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-[2'-(propan-2-yl)-2,4'-bi-1,3-thiazol-4-yl]hepta-2,6-dienoate; (2E,6E)-(4R,5S)-7-(2'-Isopropyl-[2,4']bithiazolyl-4-yl)-3,5-dimethoxy-4-methyl-hepta-2,6-dienoic acid methyl ester. CAS No. 207399-36-8. Molecular formula: C20H26N2O4S2. Mole weight: 422.56. | |
| Cystothiazole B | It is produced by the strain of Cystobacter fuscus. It has no anti-bacterial effect. CAS No. 207399-38-0. Molecular formula: C20H26N2O5S2. Mole weight: 438.56. | |
| Cytochalasin A | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytochalasin A is an HIV protease inhibitor. Alternative Names: NSC174119; Dehydrophomin; 5-Dehydrophomin; 5,5-Didehydrophomin; 2H-Oxacyclotetradecino(2,3-d)isoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-; (7S,13E,16R,21E)-7-Hydroxy-16-methyl-10-phenyl-24-Oxa[14]cytochalasa-6(12),13,21-triene-1,20,23-trione; 16-Benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-2H-Oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione. Grades: >98% by HPLC. CAS No. 14110-64-6. Molecular formula: C29H35NO5. Mole weight: 477.59. | |
| Cytochalasin C | It is produced by the strain of Metarrhizium anisopliae, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Alternative Names: 3-Benzyl-3,3a,6,6a,9,10,12,15-octahydro-6,12,15-trihydroxy-4,5,10,12-tetramethyl-1H-cycloundec[d]isoindole-1,11(2H)-dione 15-Acetate; (7S,13E,16S,18R,19E,21R)-21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-[11]Cytochalasa-5,13,19-triene-1,17-dione; [3S-(3R*,3aS*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-15-(Acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-1H-Cycloundec[d]isoindole-1,11(2H)-dione. Grades: >99% by HPLC. CAS No. 22144-76-9. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
| Cytochalasin E | It is produced by the strain of Rosellina necatrix. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Alternative Names: (7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione; NSC 175151; [4S-(1E,4R*,6S*,7E,11aR*,14R*,14aR*,15R*,15aS*,16aR*,16bR*)]-3,13,14,14a,15,15a,16a,16b-Octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione. Grades: >99% by HPLC. CAS No. 36011-19-5. Molecular formula: C28H33NO7. Mole weight: 495.56. | |
| Cytochalasin F | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Alternative Names: (7S,13E,16R,20R,21E)-6,7-Epoxy-20-hydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-13,21-diene-1,23-dione; 24-Oxa(14)cytochalasa-13,21-diene-1,23-dione,6,7-epoxy-20-hydroxy-16-methyl-10-phenyl-, (7S,13E,16R,20R,21E)-. CAS No. 36084-18-1. Molecular formula: C29H37NO5. Mole weight: 479.61. | |
| Cytochalasin G | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. CAS No. 54874-57-6. Molecular formula: C29H34N2O4. Mole weight: 474.59. | |
| Cytochalasin H | It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine H has immunosuppressive effects. Alternative Names: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-[11]Cytochalasa-6(12),13,19-trien-1-one; (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; Cytochalasin H; Kodocytochalasin 1; Paspalin P I; [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-15-(Acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; Paspalin; SC 305222; NSC305222; NSC-305222; (11)Cytochalasa-6(12),13,19-trien-1-one; phenyl-(11)cytochalasa-6(12),13,19-triene-1-one. Grades: >95% by HPLC. CAS No. 53760-19-3. Molecular formula: C30H39NO5. Mole weight: 493.63. | |
| Cytochalasin J | It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine J has immunosuppressive effects. Alternative Names: Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II; [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-2,3,3a,4,5,6,6a,9,10,11,12,15-Dodecahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; (7S,13E,16S,18R,19E,21R)-7,18,21-Trihydroxy-16,18-dimethyl-10-phenyl-[[11]cytochalasa-6(12),13,19-trien-1-one. Grades: ≥ 95%. CAS No. 56144-22-0. Molecular formula: C28H37NO4. Mole weight: 451.60. | |
| Cytochalasin K | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Alternative Names: 3H-Cyclotridec(d)oxireno(f)isoindole-8,11,12(13H)-trione, 7-(acetyloxy)-4,7,14,14a,15,15a,16a,16b-octahydro-4,6,15,15a-tetramethyl-14-(phenylmethyl)-, (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-. CAS No. 79648-72-9. Molecular formula: C32H37NO6. Mole weight: 531.64. | |
| Cytochalasin L | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Alternative Names: 24-Oxa(14)cytochalasa-13,17,21-triene-1,20,23-trione, 19-(acetyloxy)-6,7-epoxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,17E,19R,21E)-; 3H-Oxacyclotetradecino(2,3-d)oxireno(f)isoindole-8,11,13(14H)-trione, 7-(acetyloxy)-4,7,15,15a,16,16a,17a,17b-octahydro-4,6,16,16a-tetramethyl-15-(phenylmethyl)-, (1E,4S,5E,7R,9E,12aS,15S,15aS,16S,16aR,17aS,17bS)-. CAS No. 79637-87-9. Molecular formula: C32H37NO7. Mole weight: 547.64. | |
| Cytochalasin M | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Alternative Names: 24-Oxa(14)cytochalasa-13,17-diene-1,19,23-trione, 6,7-epoxy-20-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,17E,20S)-; 3H-Oxacyclotetradecino(2,3-d)oxireno(f)isoindole-7,11,13(4H,8H,14H)-trione,9,10,15,15a,16,16a,17a,17b-octahydro-8-hydroxy-4,6,16,16a-tetramethyl-15-(phenylmethyl)-, (4S-(1E,4R*,5E,8R*,12ar*,15R*,15ar*,16R*,16as*,17ar*,17br*))-. CAS No. 79648-73-0. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
| Cytogenin | It is produced by the strain of Streptoverticillium eurocidicum. It has weak cytotoxicity. Alternative Names: Antibiotic MI 43-37F 11; 8-Hydroxy-3-(hydroxymethyl)-6-methoxy-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one,8-hydroxy-3-(hydroxymethyl)-6-methoxy-. CAS No. 132971-59-6. Molecular formula: C11H10O5. Mole weight: 222.19. | |
| Cytorhodin A | It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It can inhibit the growth of P388 murine lymphocytic leukemia cells with IC50 of 2.9 ng/mL. Alternative Names: 1-Deoxyobelmycin B; A-447C; Antibiotic A-447C; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-, (7R,8R,10S)-; [7R-(7a,8b,10b)]-8-Ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[[2S-[2a,5b(2R*,5R*,6R*),6b]]-tetrahydro-6-methyl-5-[(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione. CAS No. 95599-38-5. Molecular formula: C60H88N2O20. Mole weight: 1157.34. | |
| Cytorhodin X | It is produced by the strain of Streptomyces sp. HPLY-11472 (DSM 2658). It belongs to Rhodimycin group antibiotic. The ED50 of L1210 cell is 0.36 μmol/L (The ED50 of adriamycin in the control group is 0.036 μmol/L). Alternative Names: Cytorhodin A, 7-de((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2-alpha,5-beta(2R*,5R*,6R*),6-beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-9-O-(2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)-. CAS No. 133914-58-6. Molecular formula: C48H68N2O15. Mole weight: 913.06. | |
| Cytosaminomycin A | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin A without cleavage in chicken embryo cells is 0.3-0.6 μg/mL. Alternative Names: N-[3-(Methylthio)acryloyl]-1-[4-O-[4-(dimethylamino)-4,6-dideoxy-alpha-D-glucopyranosyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]cytosine. CAS No. 157878-02-9. Molecular formula: C22H34N4O8S. Mole weight: 514.59. | |
| Cytosaminomycin B | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin B without cleavage in chicken embryo cells is 0.3-0.6 μg/mL. Alternative Names: 2(1H)-pyrimidinone, 1-[2,6-dideoxy-4-o-[4,6-dideoxy-4-(dimethylamino)-alpha-D-glucopyranosyl]-beta-L-arabino-hexopyranosyl]-4-[[4-(methylamino)benzoyl]amino]-. CAS No. 157878-03-0. Molecular formula: C26H37N5O8. Mole weight: 547.60. | |
| Cytosaminomycin C | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin C without cleavage in chicken embryo cells is 0.3-0.6 μg/mL. CAS No. 157878-04-1. Molecular formula: C23H36N4O8. Mole weight: 496.55. | |
| Cytosaminomycin D | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin D without cleavage in chicken embryo cells is 2.5 μg/mL. Alternative Names: N-(2-Methyl-2-butenoyl)-1-[4-O-[4-(dimethylamino)-4,6-dideoxy-alpha-D-glucopyranosyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]cytosine. CAS No. 157878-05-2. Molecular formula: C23H36N4O8. Mole weight: 496.55. | |
| Cytosporin A | Cytosporin A is an angiotensin II receptor antagonist produced by Cytospora sp. Cytosporin A selectively inhibits the binding of angiotensin II to the AT2 site of the receptor with IC50 of 1.5-3.0 mol/L (0.5 to 1 μg/mL). Molecular formula: C17H24O5. Mole weight: 308.37. | |
| Cytosporin B | Cytosporin B is a minor component produced by Cytospora sp. Molecular formula: C17H27ClO5. Mole weight: 346.85. | |
| Cytosporin C | Cytosporin C is a minor component produced by Cytospora sp. Molecular formula: C17H26O5. Mole weight: 310.38. | |
| Cytovaricin | Cytovaricin is an antibiotic produced by Streptomyces sp. H-230 and Str. collinus H-230. It has the activity of inhibiting Yoshida sarcoma cells and has weak anti-phytopathogenic fungi and chlorella activity. CAS No. 79553-45-0. Molecular formula: C47H80O16. Mole weight: 901.13. | |
| Cytovaricin B | Cytovaricin B is a Janus kinase-signal transducer and activation protein (JAK-STAT) inhibitor produced by Streptamyces torulosus 3197-GM1. CAS No. 129985-88-2. Molecular formula: C48H82O16. Mole weight: 915.15. | |
| Cytoxazone | Cytoxazone is a cytokine regulator produced by Streptornyces sp. RK95-31. It inhibits the production of IL-4 and IL-10 induced by Pokeween mitogen (PWM) at 6.25-25 μg/mL, but does not inhibit the production of GM-CSF induced by PWM. Alternative Names: (-)-Cytoxazone. Grades: >98%. CAS No. 42902-32-9. Molecular formula: C11H13NO4. Mole weight: 223.22. | |
| D2-eprinomectin B1a | D2-eprinomectin B1a. | |
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