BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Threonine methyl ester | D-Threonine methyl ester. Alternative Names: D-Threonine, methyl ester. CAS No. 82679-55-8. Molecular formula: C5H11NO3. Mole weight: 133.15. |  |
| D-Tryptophanamide | D-Tryptophanamide. Alternative Names: H-D-Trp-NH2. CAS No. 38689-24-6. Molecular formula: C11H13N3O. Mole weight: 203.2. | |
| D-Tyrosinamide | D-Tyrosinamide. Alternative Names: H-D-Tyr-NH2. CAS No. 111004-07-0. Molecular formula: C9H12N2O2. Mole weight: 180.2. | |
| Duazomycin A | Duazomycin A is produced by the strain of Streptomyces ambofaciens. It has the activity of anti-gram-positive bacteria, yeast and yeast-like fungi, and has strong inhibitory effect on sarcoma 180 and adenocarcinoma 755. Alternative Names: Duazomycine; Duazomycinum; N-Acetyl-6-diazo-5-oxo-L-norleucine. CAS No. 2508-89-6. Molecular formula: C8H11N3O4. Mole weight: 213.19. | |
| Duclauxin | It is produced by the strain of Penicillum stipitatum. It has inhibitory effect on Ehrlician ascites carcinoma, lymphoma L-5178 and sarcoma 37. Alternative Names: 15H-8,15a-Methano-3H,13H-benzo[de]cycloocta[1,2-g_3,4,5-d'e']bis[2]benzopyran-3,9,13,16-tetrone,17-(acetyloxy)-6b,7,8,15b-tetrahydro-4,12-dihydroxy-6b-methoxy-6,10-dimethyl-. CAS No. 1732-37-2. Molecular formula: C29H22O11. Mole weight: 546.48. | |
| Dulcoside A | Dulcoside A is a natural compound which can be isolated from Stevia rebaudiana. Alternative Names: Kaur-16-en-18-oic acid, 13-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-, β-D-glucopyranosyl ester, (4α)-. Grades: 98%. CAS No. 64432-06-0. Molecular formula: C38H60O17. Mole weight: 788.87. | |
| Dunaimycin A1 | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It's an immunosuppressant. Alternative Names: (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11-trihydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione; 10-Deoxy-Dunaimycin C1. CAS No. 140221-72-3. Molecular formula: C42H72O9. Mole weight: 721.02. | |
| Dunaimycin C1 | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It's an immunosuppressant. Alternative Names: (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11,12-tetrahydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione. CAS No. 140221-73-4. Molecular formula: C42H72O10. Mole weight: 737.02. | |
| Dunaimycin D4S | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It has weak anti-bacterial and anti-aspergillus Niger activity, and shows immunosuppressive effect in the mouse popliteal node model. CAS No. 140221-79-0. Molecular formula: C51H89NO14. Mole weight: 940.25. | |
| Duocarmycin A | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has strong antibacterial and antitumor activity. It can inhibit gram-positive bacteria such as Staphylococcus aureus and Streptococcus faecalis (MIC is less than 0.01 μg/mL), it can also inhibit klebsiella pneumoniae (MIC is 0.032 μg/mL), other bacteria and yeast (MIC is 1-10 μg/mL). Alternative Names: Antibiotic DC 88A; methyl (6R,7bR,8aS)-6-methyl-4,7-dioxo-2-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,4,5,6,7,8,8a-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylate; Methyl (2R,3bR,4aS)-2-methyl-3,8-dioxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,4,4a,5,6,8-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-2-carboxylate; DUMA; (+)-Dunnione; (+)-duocarmycin A. Grades: ≥95%. CAS No. 118292-34-5. Molecular formula: C26H25N3O8. Mole weight: 507.49. | |
| Duocarmycin B1 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-gram-positive bacteria, gram-negative bacteria and tumor activity. Alternative Names: Antibiotic DC 89B1; 1H-Pyrrolo3,2-fquinoline-2-carboxylic acid, 8-bromo-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-; Duocarmycin B(sub 1). Grades: ≥95%. CAS No. 124325-93-5. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Duocarmycin B2 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-tumor activity. Alternative Names: DUMB2; Benzo1,2-b:4,3-bdipyrrole-2-carboxylic acid, 8-(bromomethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-. CAS No. 124325-94-6. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Dustanin | Dustanin is a hopane isolated from Aschersonia. Alternative Names: 15alpha,22-dihydroxyhopane; Hopane-15α,22-diol. CAS No. 3607-96-3. Molecular formula: C30H52O2. Mole weight: 444.73. | |
| Dutomycin | It is produced by the strain of Streptomyces sp. 1725. Dutomycin has stronger cytotoxicity. 1 μg/mL of Dutomycin can completely inhibit P388 leukemia cells. Alternative Names: 1,4,6,7(6aH,10H)-Naphthacenetetrone, 8-acetyl-10-((5-((2,6-dideoxy-4-O-(2,4-dimethyl-1-oxo-2-heptenyl)-3-C-methyl-alpha-L-xylo-hexopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-10a,11-dihydro-5,6a,9,10a-tetrahydroxy-2-methoxy-12-methyl-, (2S-(2alpha(6aR*,10S*,10aS*),5beta(2Z,4S*),6alpha))-. CAS No. 146663-67-4. Molecular formula: C44H54O17. Mole weight: 854.89. | |
| D-Valinamide | D-Valinamide. CAS No. 32526-16-2. Molecular formula: C5H12N2O. Mole weight: 116.2. | |
| Dykellic acid | It is produced by the strain of Westerdykella multispora F50733. It is an immunologically active substance. It can strongly inhibit LPS-induced B cell proliferation and the production of B cell polyclonal IgM antibody, as well as T cell proliferation. The expression of IL-2 and IL-4 genes in Th cells was inhibited. CAS No. 1097679-78-1. Molecular formula: C14H16O4. Mole weight: 248.27. | |
| Dynemicin L | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Alternative Names: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylic acid, 8-chloro-5,8,9,14,15,16-hexahydro-1,4,6,17-tetrahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9R,14S,17S,18S)-(9CI). CAS No. 127032-74-0. Molecular formula: C30H22NO9Cl. Mole weight: 575.95. | |
| Dynemicin M | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Alternative Names: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grades: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49. | |
| Dynemicin N | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Alternative Names: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylicacid,5,8,9,14,15,16-hexahydro-1,4,6,8,17-pentahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9S,14S,17S,18S)-(9CI). CAS No. 127003-55-8. Molecular formula: C30H23NO10. Mole weight: 557.50. | |
| Dynemicin O | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Alternative Names: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a,17-hexahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; (8R-(8alpha,9beta,14beta,17S*,18R*))-8,9,14,15-Tetrahydro-1,4,6,8,10,17-hexahydroxy-20-methoxy-18-methyl-9,8,14-(1)butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione. CAS No. 138370-12-4. Molecular formula: C29H23NO10. Mole weight: 545.49. | |
| Dynemicin P | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Alternative Names: (1R)-3,4,4a,13,14,14a-Hexahydro-3β,4a,6,8,11,14a-hexahydroxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione,8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-. CAS No. 138370-13-5. Molecular formula: C28H21NO9. Mole weight: 515.47. | |
| Dynemicin Q | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Alternative Names: 9,8,14-(2)Buten(1)yl(4)ylideneanthra(1,2-b)benz(f)azocine-5,6,20-trione,8,9,14,15-tetrahydro-1,4,6,8,17,19-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*))-. CAS No. 138370-14-6. Molecular formula: C28H19NO9. Mole weight: 513.45. | |
| E7046 | E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Alternative Names: E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid. CAS No. 1369489-71-3. Molecular formula: C22H18F5N3O4. Mole weight: 483.39. | |
| Ebelactone A | It is produced by the strain of Streptomyces aburaviensis. It has the inhibitory effect on Esterases (IC50 is 0.56 μg/mL), Pancreatic lipase (IC50 is 0.003 μg/mL) and Cutinase on fungal cells. Alternative Names: 2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-3-methyl-, (3S-(3-alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-; (-)-ebelactone a. Grades: ≥98%. CAS No. 76808-16-7. Molecular formula: C20H34O4. Mole weight: 338.48. | |
| Ebelactone B | It is produced by the strain of Streptomyces aburaviensis. It has the inhibitory effect on Esterases (IC50 is 0.00035 μg/mL), Pancreatic lipase (IC50 is 0.0008 μg/mL) and Cutinase on fungal cells. Alternative Names: 2-Oxetanone, 3-ethyl-4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-, (3S-(3-alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-; Ebelactone; Nsc 335651. CAS No. 76808-15-6. Molecular formula: C21H36O4. Mole weight: 352.51. | |
| EC330 | EC330 is a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range, blocked formation of colonies in soft agar and inhibited angiogenesis (tube formation) in HUVEC cells. EC330 as a novel LIF inhibitor has targeted therapeutic perspectives for patients with aggressive primary tumors. Alternative Names: EC330; EC 330; EC-330; (8S,11R,13S,14S,17S)-11-(4-cyclopropylphenyl)-17-(1,1-difluoroprop-2-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one. CAS No. 2016795-77-8. Molecular formula: C30H32F2O2. Mole weight: 462.57. | |
| Echinacoside | Echinacoside, a natural polyphenolic compound, has various kinds of pharmacological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Alternative Names: 2-(3,4-Dihydroxyphenyl)ethyl 4-(3-(3,4-dihydroxyphenyl)-2-propenoate)-3-O-(b-D-glucopyranose)-6-O-(a-L-rhamnopyranose)-b-D-glucopyranoside. Grades: >98%. CAS No. 82854-37-3. Molecular formula: C35H46O20. Mole weight: 786.74. | |
| Echinocandin B | It is produced by the strain of Aspergillus rugulosus. Echinocandin can inhibit (1,3)-β-Glucan synthase, an essential component of the cell wall of susceptible fungi, and has anti-fungal activity against candida. Alternative Names: NSC 287461; 5.1:6-anhydro{(4R,5R)-4,5-dihydroxy-N(2)-[(9Z,12Z)-octadeca-9,12-dienoyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-proline}; Antibiotic A 22082; Antibiotic A 30912 factor A; Antibiotic A 30912A; Antibiotic SL 7810; Antibiotic SL 7810F. Grades: >95% by HPLC. CAS No. 54651-05-7. Molecular formula: C52H81N7O16. Mole weight: 1060.23. | |
| Echinocarpic acid | It has been isolated from the lichen Pamelia norcrambidiocarpa together with atranorin and chloroatranorin. Alternative Names: Benzoic acid, 2,4-dihydroxy-3,6-dimethyl-, (1,3-dihydro-1,4-dihydroxy-6-methoxy-3-oxo-5-isobenzofuranyl)methyl ester; 1',4'-dihydroxy-6'-methoxy-3'-oxo-1',3'-dihydroisobenzofuran-5'-ylmethyl 2,4-dihydroxy-3,6-dimethylbenzoate. CAS No. 79586-50-8. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Echinoserine | It is produced by the strain of Streptomyces tendae Tu 4031. It has anti-gram positive and negative bacteria activity, but lower than Echinomycin. CAS No. 167324-03-0. Molecular formula: C51H68N12O14S2. Mole weight: 1137.28. | |
| Echinosporin | It is produced by the strain of Bacillus brevis Vm4, Streptomyces echinos porus MK-213. It has weak anti-gram-positive bacteria and tumor activity. Alternative Names: (1S,4aS,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-8-oxo-1,5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide; (-)-Echinosporin; Antibiotic XK 213; NSC 357683; XK 213; [1S-(1α,4aβ,5β,7aβ)]-1,4a,5,7a-Tetrahydro-5-hydroxy-8-oxo-1,5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide. Grades: >98%. CAS No. 79127-35-8. Molecular formula: C10H9NO5. Mole weight: 223.18. | |
| ECHINULIN | Echinulin is isolated from Aspergillus chevalieri. Alternative Names: (3S,6S)-3-[[2-(1,1-Dimethyl-2-propenyl)-5,7-bis(3-methyl-2-butenyl)-1H-indol-3-yl]methyl]-6-methyl-2,5-piperazinedione; Echinuline. Grades: 96%. CAS No. 1859-87-6. Molecular formula: C29H39N3O2. Mole weight: 461.64. | |
| Edeine B1 | It is produced by the strain of Bacillus brevis Vm4. It can inhibit DNA replication and protein biosynthesis, and has anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast activities. Alternative Names: Glycinamide, N8-[(3S)-3-(4-hydroxyphenyl)-β-alanyl-(3S)-2-hydroxy-β-alanyl-3-amino-L-alanyl]-(3R,4S,8R)-4,8-diamino-8-carboxy-3-hydroxyoctanoyl-N-[3-[[4-(aminominomethyl)amino]butyl]amino]propyl]-. CAS No. 27656-73-1. Molecular formula: C34H60N12O10. Mole weight: 796.91. | |
| Efrotomycin | It is produced by the strain of Streptomyces lavendulae. The combination of Efrotomycin with the prolonging factor Tu inhibits protein biosynthesis. It has anti-gram-positive bacteria and negative bacteria activity, and it can inhibit coccidiosis in mice and chickens and promote the growth of pigs. Alternative Names: Producil; Antibiotic FR 02A; Efrotomicina; Efrotomycine; Mocimycin, 31-O-(6-deoxy-4-O-(6-deoxy-2,4-di-O-methyl-alpha-L-mannopyranosyl)-3-O-methyl-beta-D-allopyranosyl)-1-methyl-. CAS No. 56592-32-6. Molecular formula: C59H88N2O20. Mole weight: 1145.33. | |
| EI-1507-1 | EI-1507-1 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.23 μmol/L. Molecular formula: C20H18O6. Mole weight: 354.35. | |
| EI-1507-2 | EI-1507-2 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.42 μmol/L. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| EI-1511-3 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-3 inhibited recombinant human ICE with an IC50 of 0.09 μmol/L. Alternative Names: (2E,4E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-7-methylocta-2,4-dienamide. Molecular formula: C27H30N2O7. Mole weight: 494.54. | |
| EI-1511-5 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-5 inhibited recombinant human ICE with an IC50 of 0.38 μmol/L. Alternative Names: (2E,4E,6E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyldeca-2,4,6-trienamide. Molecular formula: C29H32N2O7. Mole weight: 520.57. | |
| EI-1625-2 | It is produced by the strain of Streptomyces sp. E-1625. EI-1625-2 inhibited recombinant human ICE with an IC50 of 0.2 μmol/L. Alternative Names: (2E)-N-[(1S,5R,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-4-methyloct-2-enamide. Molecular formula: C27H32N2O7. Mole weight: 496.55. | |
| EI-1941-1 | It is originally isolated from Farrowia sp. E-1941. EI-1941-1 inhibited recombinant human ICE with an IC50 of 0.086 μmol/L. It also inhibits elastase and cathepsin. Alternative Names: 2,3-Dihydroxy-5-propyl-1a,5,6,7a-tetrahydro-2H-oxireno[g]isochromen-7(3H)-one. CAS No. 189828-31-7. Molecular formula: C12H16O5. Mole weight: 240.25. | |
| EI-1941-2 | It is originally isolated from Farrowia sp. E-1941. EI-1941-2 inhibited recombinant human ICE with an IC50 of 0.006 μmol/L. It also inhibits elastase and cathepsin. CAS No. 189828-32-8. Molecular formula: C12H14O5. Mole weight: 238.24. | |
| EI-2128-1 | EI-2128-1 is originally isolated from Penicillum sp. E-2128. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 0.59 μmol/L. It also has anti-Gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus and Enterococcus enterococcus. Alternative Names: (2E)-N-[(1R,3S,4'S,5R,5'R,7S)-5'-Hydroxy-6-oxodihydro-3'H-spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'-furan]-4'-yl]-4,6-dimethyl-2-dodecenamide. Molecular formula: C23H35NO6. Mole weight: 421.53. | |
| EI-2346 | EI-2346 is originally isolated from Streptomyces sp. E-2346. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 3.9 μmol/L. It also inhibits elastase and cathepsin. Alternative Names: 3,10-Dihydroxy-8-[5-hydroxy-4-(hydroxymethyl)-1,3-dioxan-2-yl]-3-methyl-1-propyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione. Molecular formula: C22H26O9. Mole weight: 434.44. | |
| EIPA | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Alternative Names: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76. | |
| Ekatetrone | It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Alternative Names: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. | |
| Elaiomycin | It is produced by the strain of Streptomyces hepaticus. It has the activity of anti-gram-positive bacteria and negative bacteria, especially has strong effect on mycobacterium tuberculosis. It is a carcinogen. Alternative Names: D-threo-4-Methoxy-3-(1-octenylazoxy)-2-butanol; D-threo-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; (2S,3S)-4-Methoxy-3-(1'-cis-octenyl-cis-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, D-threo-; (E,Z)-(2S,3S)-4-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, (E,Z)-(2S,3S)-. CAS No. 23315-05-1. Molecular formula: C13H26N2O3. Mole weight: 258.36. | |
| Elaiophylin | It is produced by the strain of Streptomyces melanosporofacien. It has the activity of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as insect repellent and growth promoter for ruminants. Elaiophylin is an autophagy inhibitor, which exerts antitumor activity as a single agent in ovarian cancer cells. Alternative Names: Azalomycin B; Salbomycin; Azalomycin B; Antibiotic 5001B; Antibiotic 56-62; Elaiofilin. Grades: ≥95%. CAS No. 37318-06-2. Molecular formula: C54H88O18. Mole weight: 1025.26. | |
| Elasnin | Elasnin is isolated from certain strains of Streptomyces. Elasnin is a reversible inhibitor of elastase with IC50 values of 1.3 and 30 μg/ml for human granulocyte and pancreatic enzymes, respectively. It inhibits human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin with Ki values of 93, 69 and 224 μM, respectively. Alternative Names: 3,5-dibutyl-2-hydroxy-6-(6-oxoundecan-5-yl)-4H-pyran-4-one; 3,5-Dibutyl-6-(1-butyl-2-oxoheptyl)-4-hydroxy-2H-pyran-2-one. Grades: ≥98%. CAS No. 68112-21-0. Molecular formula: C24H40O4. Mole weight: 392.57. | |
| Elizabethin | It is produced by the strain of Streptomyces elizabethii. It has antifungal activity. CAS No. 78361-81-6. Molecular formula: C35H58O12. Mole weight: 670.83. | |
| Elloramycin | It is produced by the strain of Streptomyces olivaceus Tu 2353. It has weak activity against gram-positive bacteria, streptomycete and L-1210 leukemic cells, but has no effect on mouse leukemic P388 cells in vivo, and also has a strong inhibition of Streptomyces (including the production of bacteria themselves) activity. Alternative Names: Elloramycin A; methyl (6aR,7S,10aR)-3-[(6-deoxy-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy]-6a,7,12-trihydroxy-8,10a-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate; (6aR)-3-[(2-O,3-O,4-O-Trimethyl-6-deoxy-α-L-mannopyranosyl)oxy]-6,6a,7,10,10a,11-hexahydro-6aα,7α,12-trihydroxy-8,10aα-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylic acid methyl ester. CAS No. 97218-42-3. Molecular formula: C32H36O15. Mole weight: 660.62. | |
| Elsamicin B | Elsamicin B is produced by the strain of Actinomycetes J904-21. It is an antitumor antibiotic in the Chartreusin group. Aminoglycogen-deficient Elsamicin B shows only minimal antitumor activity. Alternative Names: 10-[(3-C-Methyl-6-deoxy-β-D-galactopyranosyl)oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione; Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methyl-; 6-Hydroxy-1-methyl-5,12-dioxo-5,12-dihydrobenzo[g][2]benzopyrano[5,4,3-cde][2]benzopyran-10-yl 6-deoxy-3-C-methylhexopyranoside. CAS No. 97068-31-0. Molecular formula: C26H22O10. Mole weight: 494.45. | |
| Elsamitrucin | Elsamitrucin is produced by the strain of Actinomycetes J904-21. It has strong anti-tumor activity of mouse tumor cells such as leukemia P388, L1210 and melanoma B16, and its anti-tumor activity is 10-30 times stronger than Chartreusin. Uses: Antibiotics, antineoplastic. Alternative Names: Elsamicin A. Grades: >95%. CAS No. 97068-30-9. Molecular formula: C33H35NO13. Mole weight: 653.63. | |
| Elsinochrome A | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Alternative Names: (1r,2r)-1,2-diacetyl-4,11-dihydroxy-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-5,10-dione; 1alpha,2beta-Diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxybenzo[ghi]perylene-4,11-dione; Benzo(ghi)perylene-4,11-dione, 1,2-diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxy-, trans-. Grades: ≥98%. CAS No. 24568-67-0. Molecular formula: C30H24O10. Mole weight: 544.51. | |
| Elsinochrome B | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Alternative Names: 1-Acetyl-5,10-dihydroxy-2-(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione. Grades: ≥98%. CAS No. 24512-58-1. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| Elsinochrome C | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Alternative Names: 5,10-Dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione; Benzo[ghi]perylene-4,11-dione,1,2-dihydro-5,10-dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-. Grades: ≥98%. CAS No. 24512-87-6. Molecular formula: C30H28O10. Mole weight: 548.54. | |
| Elsinochrome D | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Alternative Names: 12,13-Dihydro-2-hydroxy-12,13-bis(1-hydroxyethyl)-1,5,6-trimethoxybenzo[1,12]perylo[2,3-d][1,3]dioxole-3,8-dione. Grades: ≥98%. CAS No. 32500-05-3. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| EM2487 | EM2487 is produced by the strain of Streptomyces sp. Mer-2487. It inhibited HLV-1 replication in both chronically and acutely infected cells. The action occurs during the post-integration phase of the HIV-1 provirus DNA in the HIV-1 replication cycle. Molecular formula: C32H57N5O16P2. Mole weight: 829.76. | |
| Embelin | Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 uM. Alternative Names: NSC91874; NSC91874; NSC 91874; Embelin; Emberine; Embelic acid. Grades: >98%. CAS No. 550-24-3. Molecular formula: C17H26O4. Mole weight: 294.39. | |
| Emeguisin A | Emeguisin A is isolated from the fungus Emericella unguis. Emeguisin A exhibits potent antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus as well as strong antifungal activity against Cryptococcus neoformans. Grades: >95% by HPLC. CAS No. 117032-54-9. Molecular formula: C23H23ClO5. Mole weight: 414.9. | |
| Emerimicin ? | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria. Emerimicin II activity is stronger than the Emerimicin III and IV. Alternative Names: samarosporin I; Stilbellin I. CAS No. 52931-43-8. Molecular formula: C77H120N16O19. Mole weight: 1573.87. | |
| Emerimicin IIA | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria and various protozoa. The activity of Emerimicin II is stronger than the Emerimicin III and IV. Alternative Names: Ac-Trp-Ile-Gln-Aib-Ile-Thr-Aib-Leu-Aib-Hyp-Gln-Aib-Hyp-Aib-Unk; Zervamicin-II-A; Zervamicin IIA; Zervamicin IC, 3-L-glutamine-4-(2-methylalanine)-; L-Prolinamide, N-acetyl-L-tryptophyl-L-isoleucyl-L-glutaminyl-2-methylalanyl-L-isoleucyl-L-threonyl-2-methylalanyl-L-leucyl-2-methylalanyl-(4R)-4-hydroxy-L-prolyl-L-glutaminyl-2-methylalanyl-(4R)-4-hydroxy-L-prolyl-2-methylalanyl-N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-. CAS No. 79395-86-1. Molecular formula: C89H137N19O22. Mole weight: 1825.15. | |
| Emerimicin IIB | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria and various protozoa. The activity of Emerimicin II is stronger than the Emerimicin III and IV. Alternative Names: Zervamicin IIB; N-acetyl-L-tryptophyl-L-isoleucyl-L-glutaminyl-L-isovalyl-L-isoleucyl-L-threonyl-alpha-methyl-alanyl-L-leucyl-alpha-methyl-alanyl-(4R)-4-hydroxy-L-prolyl-L-glutaminyl-alpha-methyl-alanyl-(4R)-4-hydroxy-L-prolyl-alpha-methyl-alanyl-L-prolyl-L-phenylalaninol; Ac-Trp-Ile-Gln-Iva-Ile-Thr-Aib-Leu-Aib-Hyp-Gln-Aib-Hyp-Aib-Pro-Phe-ol; Zervamicin IC, 3-L-glutamine-. CAS No. 79395-85-0. Molecular formula: C90H139N19O22. Mole weight: 1839.18. | |
| Emerimicin III | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria. Emerimicin II activity is stronger than the Emerimicin III and IV. Alternative Names: samarosporin II; Stilbellin II; Antibiotic EM 3. CAS No. 52931-42-7. Molecular formula: C76H118N16O19. Mole weight: 1559.84. | |
| Emerimicins | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria. Emerimicin II activity is stronger than the Emerimicin III and IV. Alternative Names: Emerimicin; Peptaibols. CAS No. 71812-28-7. Molecular formula: C162H249N35O41. Mole weight: 3342.92. | |
| Emerin | It is produced by the strain of Aspergillus nidulans. Emerin is an antibiotic. Emerin is a protein that in humans is encoded by the EMD gene, also known as the STA gene. Mutations in emerin cause X-linked recessive Emery-Dreifuss muscular dystrophy, cardiac conduction abnormalities and dilated cardiomyopathy. Alternative Names: Epurpurin C dimethyl ether; Emerin (Aspergillus); Butanedinitrile, bis((4-methoxyphenyl)methylene)-, (Z,Z)-. CAS No. 40581-18-8. Molecular formula: C20H16N2O2. Mole weight: 316.35. | |
| Emestrin | It is produced by the strain of Mycotoxin EQ-1 Emericella sp. It has strong antifungal activity. Alternative Names: emestrin A; Emestrine. Grades: >95%. CAS No. 97816-62-1. Molecular formula: C27H22N2O10S2. Mole weight: 598.60. | |
| Emestrin B | It is produced by the strain of Emericella striata. CAS No. 107395-35-7. Molecular formula: C27H22N2O10S3. Mole weight: 630.67. | |
| Emimycin | It is produced by the strain of Streptomyces sp. 2020-I. It has anti-gram-positive bacteria, negative bacteria and brewer's yeast and other fungal activities. Alternative Names: Enimycin; Pyrazinol, 4-oxide; 2(1H)-Pyrazinone, 4-oxide; 2-Hydroxypyrazine 4-oxide; 1,2-Dihydro-2-oxopyrazine 4-oxide; 4-oxidanidyl-1H-pyrazin-4-ium-2-one. CAS No. 3735-46-4. Molecular formula: C4H4N2O2. Mole weight: 112.09. | |
| Empagliflozin α Isomer | Empagliflozin α Isomer is an isomer of empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: Empagliflozin α-Anomer; (2R,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 1620758-33-9. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empedopeptin | Empedopeptin is produced by the strain of Empedobacter haloabium G393-B445. It has anti-gram-negative bacterial activity. Alternative Names: Antibiotic BMY 28117; Antibiotic BU2517. CAS No. 87551-98-2. Molecular formula: C49H79N11O19. Mole weight: 1126.22. | |
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