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Enactin Ia
It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Alternative Names: EN-Ia; 19-hydroxyneoenactin B2; (S)-2-Amino-3,N-dihydroxy-N-(15-hydroxy-15-methyl-3,10-dioxo-hexadecyl)-propionamide. CAS No. 130640-30-1. Molecular formula: C20H38N2O6. Mole weight: 402.53.
Enactin Ib
It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Alternative Names: EN-Ib. CAS No. 137252-26-7. Molecular formula: C20H38N2O6. Mole weight: 402.53.
Enactin-Va
It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Alternative Names: EN-Va; 14-dihydroneoenactin M1; (S)-2-Amino-3,N-dihydroxy-N-(10-hydroxy-14-methyl-3-oxo-pentadecyl)-propionamide. CAS No. 130640-31-2. Molecular formula: C19H38N2O5. Mole weight: 374.52.
Enacyloxin IIa
It is produced by the strain of Frateuria sp. W-315. It is a polyene antibiotic, which has the activity of anti-gram-positive bacteria and negative bacteria. the activity of anti-fungus is weak, and has no effect on yeast. Alternative Names: (1S,3R,4S)-3-{[(2E,4E,6E,8E,10Z,12S,13R,14S,17R,18S,19R,20E)-19-(carbamoyloxy)-11,18-dichloro-13,14,17-trihydroxy-6,12-dimethyl-15-oxotricosa-2,4,6,8,10,20-hexaenoyl]oxy}-4-hydroxycyclohexanecarboxylic acid; Enacyloxin II; Enacyloxin iia; Enx iia. CAS No. 126518-41-0. Molecular formula: C33H45Cl2NO11. Mole weight: 702.62.
Enamidonin
It is produced by the strain of Streptomyces sp. 91-75. It's a lipopeptide antibiotic. It inhibits EGF-dependent [3H] thymidine involvement in Balb/MK cells (IC50 is 10 μg/mL), and it can restore the deformed SRCTS-NRK form to the normal flat form (ED50 is 10 μg/mL). No antimicrobial activity. Alternative Names: Antibiotic RK 75. CAS No. 162559-40-2. Molecular formula: C37H51N7O7. Mole weight: 705.84.
Enaminomycin A
It is produced by the strain of Streptomyces baarnensis 13120. It has activity against gram-positive bacteria, gram-negative bacteria and plant pathogenic fungi (weak), and it has the inhibitory effect of L-1210. Alternative Names: (1S,6R)-4-amino-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid. CAS No. 68330-49-4. Molecular formula: C7H5NO5. Mole weight: 183.12.
Enaminomycin B
It is produced by the strain of Streptomyces baarnensis 13120. It has anti-gram positive bacteria and negative bacteria activity. Alternative Names: 7-Oxabicyclo(4.1.0)hept-3-ene-3-carboxylic acid, 4-amino-5-hydroxy-2-oxo-5-(2-oxopropyl)-, (1S-(1-alpha,5-beta-6-alpha))-; (1S,5S,6R)-4-amino-5-hydroxy-2-oxo-5-(2-oxopropyl)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid. CAS No. 68245-17-0. Molecular formula: C10H11NO6. Mole weight: 241.20.
Enaminomycin C
It is produced by the strain of Streptomyces baarnensis 13120. It has weak activity against gram-positive bacteria and negative bacteria. Alternative Names: (1S,6β)-4-Amino-5α-hydroxy-2-oxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid; 7-Oxabicyclo(4.1.0)hept-3-ene-3-carboxylic acid, 4-amino-5-hydroxy-2-oxo-, (1S-(1-alpha,5-beta,6-alpha))-; (1S,2S,6S)-3-amino-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-ene-4-carboxylic acid. CAS No. 68245-16-9. Molecular formula: C7H7NO5. Mole weight: 185.13.
Endophenazine A
It is produced by the strain of Streptomyces anulatus. It has activity against gram-positive bacteria and filamentous fungi such as mucor and Penicillium. Its weeding ability to Lemna minor is relatively low. Alternative Names: 1-Phenazinecarboxylic acid, 9-(3-methyl-2-butenyl)-; 9-(3-Methyl-2-buten-1-yl)-1-phenazinecarboxylic Acid. CAS No. 86125-71-5. Molecular formula: C18H16N2O2. Mole weight: 292.33.
Endophenazine B
It is produced by the strain of Streptomyces anulatus. It's a phenazine antibiotic, and it has low herbicidal activity against Lemna minor. Alternative Names: 5,7-Dihydro-5-methyl-9-(3-methyl-2-buten-1-yl)-7-oxo-1-phenazinecarboxylic Acid. CAS No. 479415-40-2. Molecular formula: C19H18N2O3. Mole weight: 322.36.
Endophenazine C
It is produced by the strain of Streptomyces anulatus. It has activity against gram-positive bacteria and filamentous fungi such as mucor and Penicillium. Molecular formula: C19H20N2O2. Mole weight: 308.37.
Endophenazine D
It is produced by the strain of Streptomyces anulatus. It has activity against gram-positive bacteria and filamentous fungi such as mucor and Penicillium. It has herbicidal activity against Lemna minor. Molecular formula: C15H12N2O4. Mole weight: 284.27.
Enduracidin
It is produced by the strain of Streptomyces fungicidicus. Enramycin is a polypeptide antibiotic, and it has anti-gram-positive bacteria and mycobacterium activity. Enramycin is composed of two different compounds: Enramycin A and enramycin B. Alternative Names: Enramycin; Enramycin Premix; Enramicina; Enramycinum; Enradin. Grades: >95%. CAS No. 11115-82-5. Molecular formula: C107H138Cl2N26O31 (Enramycin A); C108H140Cl2N26O31 (Enramycin B). Mole weight: 2550.21 (Enramycin A); 2564.24 (Enramycin B).
Enduracidin A hydrochloride
It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Alternative Names: Enduracidin A HCl; Enramycin A hydrochloride. CAS No. 33368-20-6. Molecular formula: C107H138Cl2N26O31.HCl. Mole weight: 2391.76.
Enduracidin B hydrochloride
It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Alternative Names: Enduracidin B HCl; Enramycin B hydrochloride. CAS No. 34765-98-5. Molecular formula: C108H140Cl2N26O31.HCl. Mole weight: 2405.78.
Endusamycin
Endusamycin is produced by the strain of Streptomyces endus subsp. aureus. It has activity against gram-positive bacteria, some anaerobic bacteria, Eimeria tenella, E.acervulina. The feed with mycorycin of 10-40 μg/g was effective for coccidioides infection. Alternative Names: Dianemycin, 19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-15-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-, (15(2S,5S,6R))-. CAS No. 100242-41-9. Molecular formula: C47H78O14. Mole weight: 867.11.
Engeletin
Engeletin is a flavonoid glycoside isolated from the leaves of Engelhardtia roxburghiana Wall. It inhibits a recombinant human aldose reductase. Uses: Anti-inflammatory. Alternative Names: Dihydrokaempferol 3-O-a-L-rhamnopyranoside; Engelitin; (2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-3-yl 6-deoxy-a-L-mannopyranoside. Grades: 96.5%. CAS No. 572-31-6. Molecular formula: C21H22O10. Mole weight: 434.39.
ENNIATIN B
It is produced by the strain of Fusarium orthoceras var. enniatinum. It has insecticidal and antifungal activity. Uses: Anti-bacterial agents. Alternative Names: 3-N-Methylvaline Enniatin; Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]; Cyclo(3-methyl-D-2-hydroxybutanoyl-N-methyl-L-valyl-3-methyl-D-2-hydroxybutanoyl-N-methyl-L-valyl-3-methyl-D-2-hydroxybutanoyl-N-methyl-L-valyl). Grades: >99% by HPLC. CAS No. 917-13-5. Molecular formula: C33H57N3O9. Mole weight: 639.82.
Enniatin B1
A family of depsipeptide ionophores, produced by several fusarium species. It has antibiotic properties. It is a cytotoxic and insecticidal agent. Alternative Names: 2-(N-Methyl-L-isoleucine)enniatin B; Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]; cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl]. Grades: >99% by HPLC. CAS No. 19914-20-6. Molecular formula: C34H59N3O9. Mole weight: 653.85.
Enniatin complex
A complex of depsipeptides produced by several fusarium species. the complex contains 4 major components: A, A1, B and B1 together with minor amounts of enniatins C, D, E and F. Alternative Names: cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl] compound with cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-L-valyl] compound with cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl] compound with cyclo[N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl]. Grades: >95% by HPLC. CAS No. 11113-62-5. Molecular formula: C36H63N3O9.C35H61N3O9.C34H59N3O9.C33H57N3O9. Mole weight: 2643.46.
Enniatin F
It is produced by the strain of Fusarium orthoceras var. enniatinum. It has insecticidal and antifungal activity, and it also can inhibit Acylcoa, cholesterol acyltransferase (ACAT). Alternative Names: Enniatin A, 2-(N-methyl-L-leucine)-; Cyclo(hiv-Me-leu-hiv-Me-ile-hiv-Me-ile). CAS No. 144446-20-8. Molecular formula: C36H63N3O9. Mole weight: 681.90.
Enopeptin A
It is produced by the strain of Streptomyces griseus. It has activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and it also has antibacterial activity of phage. Alternative Names: N-[[(2E,4E,6E,8E,10E)-12-(2-Hydroxy-5-oxo-1-cyclopentenylamino)-1,12-dioxo-2,4,6,8,10-dodecapentenyl]-L-Phe-]cyclo[L-Ser*-L-Pro-N-methyl-L-Ala-L-Ala-4β-methyl-L-Pro-]; [trans-(all-E)]-1-[N-[N-[1-[N-[N-[12-[(2-Hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,12-dioxo-2,4,6,8,10-dodecapentaenyl]-L-phenylalanyl]-L-seryl]-L-prolyl]-N-methyl-L-alanyl]-L-alanyl]-4-methyl-L-proline ξ-lactone; Enopeptin II; NSC657143. Grades: >95% by HPLC. CAS No. 139601-96-0. Molecular formula: C47H57N7O11. Mole weight: 896.00.
Enoxacin
Enoxacin is an oral broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections and gonorrhea. Insomnia is a common adverse effect. Uses: Anti-bacterial agents. Alternative Names: R41468; R41468; R-41468; PD 107779; PD-107779; PD107779; Penetrex; Enoxacine; Comprecin. Grades: >98%. CAS No. 74011-58-8. Molecular formula: C15H17FN4O3. Mole weight: 320.32.
Enrofloxacin hydrochloride
Enrofloxacin hydrochloride is a fluoroquinolone antibiotic commonly used in veterinary medicine. Alternative Names: Enrofloxacin HCl. CAS No. 112732-17-9. Molecular formula: C19H22FN3O3.HCl. Mole weight: 395.86.
Enterocin
It is produced by the strain of Streptomyces candidus var. entrosttaticus WS-8095, Str. viridochromogenes M-127. It has the activity of anti-gram-positive bacteria and negative bacteria, has the synergistic effect with streptomycin and chloramphenicol, and has the effect of weeding and affecting the metabolism of isoleucine. Alternative Names: Vulgamycin; 3,6-Methanocyclopenta(c)pyran-1(3H)-one, 7-benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-, (3R,4aR,5S,6S,7S,7aS,8R)-; [3R-(3α,4aβ,5α,6β,7β,7aβ,8R*)]-7-Benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-3,6-methanocyclopenta[c]pyran-1(3H)-one. Grades: >95% by HPLC. CAS No. 59678-46-5. Molecular formula: C22H20O10. Mole weight: 444.39.
Enteromycin carboxamide
It is produced by the strain of Str. sp. AO-126. It has anti-gram positive bacteria and negative bacteria activity. Alternative Names: 3-(2-(Methyl-aci-nitro)acetamido)acrylamide; Acrylamide, 3-(2-(methyl-aci-nitro)acetamido)-; 3-(((Methyl-aci-nitro)acetyl)amino)-2-propenamide; 2-Propenamide, 3-(((methyl-aci-nitro)acetyl)amino)-. CAS No. 998-90-3. Molecular formula: C6H9N3O4. Mole weight: 187.15.
Epanorin
Epanorin is a lichen metabolite that can inhibit the proliferation of MCF-7 breast cancer cells. Alternative Names: L-Leucine, N-[(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)phenylacetyl]-, methyl ester; N-[2-(3-Hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-phenylacetyl]-L-leucine methyl ester; (-)-Epanorin. CAS No. 18463-10-0. Molecular formula: C25H25NO6. Mole weight: 435.47.
EP Chlorpheniramine Maleate Impurity A (2HCl salt form)
An impurity of Chlorpheniramine. Chlorpheniramine is an antihistamine used to prevent symptoms of allergy. It acts via inhibiting histamine produced during anaphylaxis. Alternative Names: 2-(4-Chlorophenyl)-4-(dimethylamino)-2-(2-(dimethylamino)ethyl)butanenitrile; 2-(4-Chlorophenyl)-4-(dimethylamino)-2-[2-(dimethylamino)ethyl]butanenitrile dihydrochloride. Grades: 95%. Molecular formula: C16H26Cl3N3. Mole weight: 366.761.
Epelmycin A
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Alternative Names: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2alpha,5beta(2S*,6R*),6beta))-tetrahydro-6-methyl-5-((tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-25-0. Molecular formula: C42H53NO15. Mole weight: 811.87.
Epelmycin B
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Alternative Names: 11-Hydroxyauramycin B. CAS No. 107807-24-9. Molecular formula: C42H51NO16. Mole weight: 825.85.
Epelmycin C
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Alternative Names: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-23-8. Molecular formula: C36H45NO14. Mole weight: 715.74.
Epelmycin D
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Alternative Names: Violamycin A4; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-22-7. Molecular formula: C30H35NO11. Mole weight: 585.60.
Epelmycin E
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Alternative Names: 11-Hydroxyaclacinomycin A; 1-Naphthacenecarboxylic acid,1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,12-tetrahydroxy-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; sigma-Rmn-A; epsilon-RMN-A. CAS No. 76264-93-2. Molecular formula: C42H53NO16. Mole weight: 827.87.
Epianhydrochlortetracycline hydrochloride
A secondary degradation product formed by dehydration of epichlortetracycline at the C6 position to aromatise the B ring. It is an important standard for monitoring tetracycline stability. Alternative Names: 4-Epianhydrochlortetracycline hydrochloride; [4R-(4α,4aβ,12aβ)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Monohydrochloride; 4-Epianhydrochlortetracycline HCl. Grades: >95% by HPLC. CAS No. 158018-53-2. Molecular formula: C22H22Cl2N2O7. Mole weight: 497.33.
epi-Avermectin B1a
It is a base-catalysed intermediate in the decomposition of avermectin B1a. It has only very weak activity as a nematocide showing 100-fold less of biological activity compared with the parent avermectin. It is an environmental degradation product. Alternative Names: Avermectin B1a, epi-; 2-epi-Abamectin; (2S)-5-O-demethyl-avermectin A1a. Grades: >95% by HPLC. CAS No. 106434-14-4. Molecular formula: C48H72O14. Mole weight: 873.08.
Epibenzomalvin E
Epibenzomalvin E is a new substance P inhibitor from Penicillium. Grades: >95% by HPLC. Molecular formula: C24H19N3O3. Mole weight: 397.4.
Epicillin
It is produced by the strain of Semisynthetic broad-spectrum penicillin. Its antibacterial spectrum, antibacterial activity, pharmacokinetic properties and curative effect are similar to Ampicillin. Alternative Names: Dexacillin; Dihydroampicillin; Epicilline; Epicillinum; Epicilina; 6-((Amino-1,4-cyclohexadien-1-ylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid (2S-(2alpha,5alpha,6beta,(S*)))-; 6-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-. CAS No. 26774-90-3. Molecular formula: C16H21N3O4S. Mole weight: 351.43.
Epicoccamide
It is an ornate linear fatty acid with an acyl tetronic acid terminus and glycosidic alkyl terminus. It is originally isolated from epicoccum purpurascens. It is non-cytotoxic, unlike the weak activity shown by related analogues Epicoccamides B, C and D. Alternative Names: 5-hydroxy-1,2-dimethyl-4-(2-methyl-16-(((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexadecanoyl)-1,2-dihydro-3H-pyrrol-3-one; 1,2-Dihydro-5-hydroxy-4-[16-(β-D-mannopyranosyloxy)-2-methyl-1-oxohexadecyl]-1,2-dimethyl-3H-pyrrol-3-one. Grades: >98% by HPLC. CAS No. 606139-26-8. Molecular formula: C29H51NO9. Mole weight: 557.72.
Epi-cochlioquinone A
It is produced by the strain of Stachybitrys bisbyi. It can inhibit rat liver microsomal ACAT with IC50 of 1.7 μmol/L, inhibit plasma lecithin cholesterol acyltransferase (LCAT) with IC50 of 15.8 μmol/L, and inhibit cholesterol absorption in rats by 50% at 75 mg/kg. Alternative Names: Epicochlioquinone A; (8-alpha)-Cochlioquinone A; Cochlioquinone A, (8-alpha)-. CAS No. 147384-57-4. Molecular formula: C30H44O8. Mole weight: 532.67.
Epicorazine A
It is produced by the strain of Epicoccum nigrum. It has activity against gram-positive bacteria, including methicillin-resistant staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MIC is 12.5-25 μg/mL. It also has effect on candida albicans with MIC of 25 μg/mL. Alternative Names: (4S)-4,4aα,7,7aβ,11,11aα,14,14aβ-Octahydro-4α,11α-dihydroxy-8H,13H-6aβ,13aβ-epidithio-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13-tetrone; 8H,13H-6A,13A-Epidithio-1H,6H-pyrazino(1,2-A:4,5-A')diindole-1,6,8,13-tetrone,4,4A,7,7A,11,11A,14,14A-octahydro-4,11-dihydroxy-, (4S-(4alpha,4aalpha,6abeta,7abeta,11alpha,11aalpha,13abeta,14abeta))-. CAS No. 62256-05-7. Molecular formula: C18H16N2O6S2. Mole weight: 420.46.
Epicorazine B
It is produced by the strain of Epicoccum nigrum. It has activity against gram-positive bacteria, including methicillin-resistant staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MIC is 12.5-25 μg/mL. It also has effect on candida albicans with MIC of 25 μg/mL. Alternative Names: (4S)-4,4aα,7,7aβ,11,11aα,14,14aβ-Octahydro-4α,11α-dihydroxy-8H,13H-6aβ,13aβ-epidithio-1H,6H-pyrazino[1,2-a:4,5-a']diindole-1,6,8,13-tetrone. CAS No. 69176-72-3. Molecular formula: C18H16N2O6S2. Mole weight: 420.46.
Epiderstatin
Epiderstatin is a glutarimide antibiotic produced by Streptomyces pulveraceus sub sp. epiderstagenes. It has the activity of inhibiting the filamentous division induced by epidermal growth factor (EGF), but does not inhibit EGF-receptor kinase (EGF-receptor kinase). It has only weak antifungal activity and no antibacterial effect. Alternative Names: 4-(3-(3,5-Dimethyl-2-oxopiperidin-6-ylidene)-2-oxopropyl)-2,6-piperidinedione. CAS No. 126602-16-2. Molecular formula: C15H20N2O4. Mole weight: 292.33.
Epi-doramectin
It is a base-catalysed intermediate in the decomposition of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Alternative Names: (2S)-25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a; Doramectin, epi-. Grades: >95% by HPLC. CAS No. 1987882-62-1. Molecular formula: C50H74O14. Mole weight: 899.11.
Epidoramectin Aglycone
It is a base-catalysed intermediate produced by hydrolysis of the disaccharide unit of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Alternative Names: 2-Epidoramectin Aglycone. Molecular formula: C36H50O8. Mole weight: 610.78.
Epidoramectin Monosaccharide
It is a base-catalysed intermediate produced by selective hydrolysis of the terminal saccharide unit of doramectin. It is formed by epimerisation at the 2-position which ultimately rearranges irreversibly to the isomeric alkene analogue. Alternative Names: 2-Epidoramectin Monosaccharide. Molecular formula: C43H62O11. Mole weight: 754.94.
Epiequisetin
It is a minor isomer of equisetin and a potent inhibitor of HIV-integrase produced by a number of species of Fusarium. It has comparable phytotoxicity to equisetin. Alternative Names: 5-Epiequisetin; (3E,5R)-5-(Hydroxymethyl)-3-[hydroxy[(1S,2R,4aS,6R,8aR)-1,2,4a,5,6,7,8,8a-octahydro-1,6-dimethyl-2-(1E)-1-propen-1-yl-1-naphthalenyl]methylene]-1-methyl-2,4-pyrrolidinedione; 3-epi-Equisetin; epi-Equisetin; 5'-epi-Equisetin. Grades: >98% by HPLC. CAS No. 255377-45-8. Molecular formula: C22H31NO4. Mole weight: 373.49.
Epigomisin O
Epigomisin O is a lignan isolated from the fruits of Schizandra chinensis. Alternative Names: Epigomisin O; 73036-31-4; UNII-BC1N1HR50PBC1N1HR50P(8S,9S,10S)-3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-8-ol. Grades: >98%. CAS No. 73036-31-4. Molecular formula: C23H28O7. Mole weight: 416.47.
Epigrisorixin
Epigrisorixin, a new polyether carboxylic antibiotic. Epigrisorixin is an epimer produced by the transformation of Grisorixin by Strepto-myces hygroscopicus NRRL B-1865. Molecular formula: C40H68O10. Mole weight: 708.96.
Epihygromycin
Epihygromycin is a glycoside antibiotic produced by Streptomyces noboritoensis KCC-S-0065. It has weak activity against Gram-positive bacteria. CAS No. 75081-92-4. Molecular formula: C23H29NO12. Mole weight: 511.47.
Epiisoshamixanthone
It is a minor metabolite of Aspergillus variecolor. Alternative Names: epi-Isoshamixanthone; (-)-2,3-Dihydro-1,11-dihydroxy-5-methyl-10-(3-methyl-2-butenyl)-2-(1-methylethenyl)pyrano[3,2-a]xanthen-12(1H)-one; Pyrano[3,2-a]xanthen-12(1H)-one, 2,3-dihydro-1,11-dihydroxy-5-methyl-10-(3-methyl-2-butenyl)-2-(1-methylethenyl)-, (10R,11R)-rel-(-)-; 2,3-Dihydro-1beta,11-dihydroxy-5-methyl-10-(3-methyl-2-butenyl)-2beta-(1-methylvinyl)pyrano[3,2-a]xanthen-12(1H)-one; (1S,2S)-1,11-dihydroxy-5-methyl-10-(3-methylbut-2-en-1-yl)-2-(prop-1-en-2-yl)-2,3-dihydropyrano[3,2-a]xanthen-12(1H)-one. CAS No. 55826-54-5. Molecular formula: C25H26O5. Mole weight: 406.47.
Epimagnolin A
Epimagnolin A is a lignan isolated from the dried flower buds of Magnolia biondii Pamp. Alternative Names: (3S,3aR,6R,6aR)-3-(3,4-dimethoxyphenyl)-6-(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan. Grades: >98%. CAS No. 41689-51-4. Molecular formula: C23H28O7. Mole weight: 416.47.
Epirubicin
Epirubicin, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. It is clinically active against a broad range of tumor types, including breast cancer, malignant lymphomas, soft tissue sarcomas, lung cancer, pleural mesothelioma, gastrointestinal cancer, head and neck cancer, ovarian cancer, prostatic carcinoma, transitional bladder carcinoma and so on. Alternative Names: Pharmorubicin; Ellence; Epiadriamycin; Epidoxorubicin; 4'-Epiadriamycin; Epirubicine; Pidorubicine; NSC 256942; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; (8S-cis)-4'-Epidoxorubicin; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside. Grades: >98%. CAS No. 56420-45-2. Molecular formula: C27H29NO11. Mole weight: 543.52.
Epithienamycin A
Epithienamycin A is a carbapenem antibiotic produced by Streptomyces flavogriseus MA-4434 and MB-4638. It has anti-gram-positive bacteria and anti-gram-negative bacteria activity. CAS No. 63582-78-5. Molecular formula: C13H18N2O5S. Mole weight: 314.36.
Epithienamycin B
Epithienamycin B is a carbapenem antibiotic produced by Streptomyces flavogriseus MA-4434 and MB-4638. It has anti-gram-positive bacteria and anti-gram-negative bacteria activity. Molecular formula: C13H16N2O5S. Mole weight: 312.34.
Epithienamycin C
Epithienamycin C is a carbapenem antibiotic produced by the strain of Str. flavogriseus. It has anti-gram-positive and gram-negative bacteria activity. Antibiotic 890A3 is a stereoisomer of Antibiotic 890A1, and its antibacterial spectrum and antibacterial activity are the same as Antibiotic 890A1. Alternative Names: Antibiotic 890A3; (5R)-3-[[2-(Acetylamino)ethyl]thio]-6β-[(S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Antbiotic PS-3B; Antibiotic MM-22381; MM-22381; 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[2-(acetylamino)ethyl]thio]-6-[(1S)-1-hydroxyethyl]-7-oxo-, (5R,6S)-. CAS No. 63599-16-6. Molecular formula: C13H18N2O5S. Mole weight: 314.36.
Epithienamycin D
Epithienamycin D is a carbapenem antibiotic produced by Streptomyces flavogriseus MA-4434 and MB-4638. It has anti-gram-positive bacteria and anti-gram-negative bacteria activity. Alternative Names: carbapenem MM22383; MM22383. CAS No. 65322-98-7. Molecular formula: C13H16N2O5S. Mole weight: 312.34.
Epithienamycin E
Epithienamycin E is a carbapenem antibiotic produced by Streptomyces flavogriseus MA-4434 and MB-4638. It has anti-gram-positive bacteria and anti-gram-negative bacteria activity. Alternative Names: AB-110-D Antibiotic; Antibiotic AB 110-D; AB-110-D. Grades: >98%. CAS No. 79057-46-8. Molecular formula: C13H16N2O8S2. Mole weight: 392.40.
Epithienamycin F
Epithienamycin F is a carbapenem antibiotic produced by Streptomyces flavogriseus MA-4434 and MB-4638. It has anti-gram-positive bacteria and anti-gram-negative bacteria activity. CAS No. 79057-45-7. Molecular formula: C13H18N2O8S2. Mole weight: 394.42.
Epitrametol
Epitrametol is produced from the culture medium of Bjerkandera sp. BOS55. Alternative Names: 1,2-Propanediol, 1-(3-chloro-4-methoxyphenyl)-, (1R,2R)-rel-. Grades: ≥98%. CAS No. 627538-65-2. Molecular formula: C10H13ClO3. Mole weight: 216.66.
Epivaliolamine
Epivaliolamine is a pseudo-aminosugars produced by Streptomyces hygroscopicus sub sp. limoneue. It has a very weak inhibitory substance α-Glucosidase activity. Molecular formula: C7H15NO6. Mole weight: 209.20.
Epoformin
Epoformin is an antibiotic produced by Penicillum claviforme. It has only weak antibacterial activity, but it has a strong effect on PS cells and a poor effect on sarcoma L-1210. Alternative Names: Antibiotic 417-A. CAS No. 52146-62-0. Molecular formula: C7H8O3. Mole weight: 140.14.
Eponemycin
Eponemycin is an antibiotic against B16 melanoma produced by Streptornyces hygroscopicus No. P247-71. The in vivo test has good curative effect on B16 melanoma and moderate curative effect on L1210 leukemia, but the survival period of mice bearing P388 leukemia is not significantly prolonged. Alternative Names: Antibiotic BU 3862T; 1,2-Epoxy-2-hydroxymethyl-4-(N-isooctanoylserylamino)-6-methylhept-6-ene-3-one. CAS No. 126509-46-4. Molecular formula: C20H34N2O6. Mole weight: 398.49.
Epopromycin A
Epopromycin A is an antibiotic produced by Streptornyces sp. NK04000. It has inhibitory effect on plant protoplast cell wall synthesis. CAS No. 153540-55-7. Molecular formula: C21H36N2O6. Mole weight: 412.52.
Epopromycin B
Epopromycin B is an antibiotic produced by Streptornyces sp. NK04000. It has inhibitory effect on plant protoplast cell wall synthesis. Alternative Names: (+)-Epopromycin B. CAS No. 153540-56-8. Molecular formula: C21H38N2O6. Mole weight: 414.53.
Epostatin
Epostatin is a dipeptidase II inhibitor produced by Streptomyces sp. MJ 995-OF5. It can inhibit DPP-II with an IC50 of 9.6 μg/mL, and has a weak inhibitory effect on other dipeptidase peptidases. Alternative Names: L-Glutamine, N(sup 2)-(4-(2-hexyl-2,3,4,4a-tetrahydrocyclopent(b)oxireno(c)pyridin-7(1aH)-ylidene)-1-oxo-2-butenyl)-. Grades: >98%. CAS No. 181372-99-6. Molecular formula: C23H33N3O5. Mole weight: 431.52.
Epothilon A
Epothilons A is a 16-membered macrolide antibiotic produced by the myxobacterium Sorangium cellulosum. It has strong cytotoxicity and has the effect of resisting plant pathogenic fungi. Uses: Antineoplastic agents. Alternative Names: (-)-Epothilone A; Epo A; NSC-684362; (1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-5,7,9,9-tetramethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione. Grades: >98%. CAS No. 152044-53-6. Molecular formula: C26H39NO6S. Mole weight: 493.65.
Epothilon B
Epothilons B is a 16-membered macrolide antibiotic produced by the myxobacterium Sorangium cellulosum, which is used as a microtubule stabilization agent (EC0.01 = 1.8 μM). It has strong cytotoxicity and has the effect of resisting plant pathogenic fungi. Uses: Antineoplastic agents. Alternative Names: Patupilone; (-)-Epothilone B. Grades: 98%. CAS No. 152044-54-7. Molecular formula: C27H41NO6S. Mole weight: 507.68.
Epothilone C
Epothilone C is a novel microtubule inhibitor and acts as an antineoplastic agent. Epothilones are originally isolated from cellulose-degrading myxobacterium Sorangium cellulosum. Alternative Names: (-)-Deoxyepothilone A; (-)-Desoxyepothilone A; Desoxyepothilone A. CAS No. 186692-73-9. Molecular formula: C26H39NO5S. Mole weight: 477.66.
Epoxomicin
Epoxomicin is a naturally occurring selective proteasome inhibitor with anti-inflammatory activity. Uses: Proteasome inhibitors. Alternative Names: BU-4061T. Grades: >98%. CAS No. 134381-21-8. Molecular formula: C28H50N4O7. Mole weight: 554.72.
Epoxycytochalasin H
Epoxycytochalasin H is a metabolite of Phomopsis sojae. It has a plant growth inhibitory effect. CAS No. 96639-05-3. Molecular formula: C30H39NO5. Mole weight: 493.63.