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Fosfazinomycin B
Fosfazinomycin B is produced by the strain of Streptomyces lavendofoliae. It has the activity of resisting plant pathogenic fungi such as Xanthomonas oryzae. Alternative Names: L-Arginine 2-[hydroxy(1-hydroxy-2-methoxy-2-oxoethyl)phosphinyl]-2-methyl hydrazide. CAS No. 87423-11-8. Molecular formula: C10H23N6O6P. Mole weight: 354.30.
Fosfocytocin
It is produced by the strain of Pseudomonas fluorescens PK-52. It has very weak antibacterial activity. Alternative Names: Tan 1022; Cytidine 5'-(trihydrogen diphosphate), P'-(2-(formylhydroxyamino)ethyl) ester; 1-{5-O-[{[{2-[Formyl(hydroxy)amino]ethoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]pentofuranosyl}-4-imino-1,4-dihydropyrimidin-2-ol. CAS No. 126986-25-2. Molecular formula: C12H20N4O13P2. Mole weight: 490.25.
Fosfomycin calcium
Fosfomycin calcium is the calcium salt form of Fosfomycin, produced by Streptomyces. Fosfomycin is an antibiotic that is primarily used to treat bladder infections. Fosfomycin inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. Alternative Names: Phosphomycin calcium; Phosphonomycin calcium; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt; Phosphonic acid, (1,2-epoxypropyl)-, calcium salt, cis-(-)-; Phosphonic acid, (3-methyloxiranyl)-, calcium salt, (2R-cis)-. Grades: ≥98%. CAS No. 26472-47-9. Molecular formula: C3H7O4P.xCa. Mole weight: 138.06 (free acid).
Fosfonochlorin
It is produced by the strain of Talaromyces flavus SANK 15680 and Fusarium oxysporum SANK 10182. Chloroacetylphosphoric acid only has the activity of anti-proteus bacteria, but in the presence of glucose-6-phosphate (G-6-P), it is also effective against Staphylococcus aureus, Escherichia coli, Haemophilus haemophilus, some Shigella and Salmonella bacteria. The mechanism of antibacterial action is to inhibit cell wall biosynthesis and affect the formation of plasmoglobin. Alternative Names: (chloroacetyl)phosphonic acid; Chloroacetylphosphonate. Grades: 98%. CAS No. 89699-33-2. Molecular formula: C2H4ClO4P. Mole weight: 158.48.
Fosmidomycin
Fosmidomycin is produced by the strain of Streptomyces lavendulae 8006. Fosmidomycin has anti-gram-positive and anti-gram-negative activities. Alternative Names: Fosmidomycina; 3-(N-hydroxyformamido)propylphosphonic acid; FR-31564. Grades: 95%. CAS No. 66508-53-0. Molecular formula: C4H10NO5P. Mole weight: 183.10.
Fosmidomycin sodium salt
Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Alternative Names: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grades: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08.
Fostriecin
The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Alternative Names: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grades: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39.
FR-182877
FR-182877 is produced by the strain of Streptomyces sp. No. 9885. It has a strong effect on rat ascites and solid tumors in vivo, and has no antibacterial activity. Molecular formula: C24H32O5. Mole weight: 400.51.
FR-191512
It is a polyphenolic compound with anti-influenza A virus effect. Alternative Names: FR191512. Molecular formula: C38H38O16. Mole weight: 750.70.
FR198248
FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Alternative Names: FR-198248;1,5,6,7-Isobenzofurantetrol, 1,3-dihydro-4-methyl-;197316-54-4;1-O-Demethyl-FR-202306;6ZL0C9ER7N;2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde;364342-83-6;UNII-6ZL0C9ER7N;SCHEMBL1527081;Q27265782. Grades: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17.
FR225659
FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21.
FR-235222
FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Alternative Names: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69.
FR 252921
FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67.
FR-252922
FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72.
FR-29038
It is originally isolated from Nocardia uniformis subsp. tsuyamanensis. FR-29038 has anti-Bacillus, Escherichia, Klebsiella, Pseudomonas, Salmonella, Shigella and other family bacteria activities. Alternative Names: Antibiotic FR 29038; BRN 3578863; O-{4-[1-Amino-2-({1-[carboxy(4-hydroxyphenyl)methyl]-2-oxoazetidin-3-yl}imino)-2-hydroxyethyl]phenyl}homoserine. CAS No. 59511-12-5. Molecular formula: C23H26N4O8. Mole weight: 486.47.
FR 32863
FR 32863 is produced by the strain of Streptomyces lavendulae 8006. FR 32863 has anti-gram-positive and anti-gram-negative activities. Alternative Names: Antibiotic FR 32863; Antibiotic FR 900136; BRN 2092108; FR-32863; (E)-(3-(Formylhydroxyamino)-1-propenyl)phosphonic acid. CAS No. 66508-88-1. Molecular formula: C4H8NO5P. Mole weight: 181.08.
FR-33289
FR-33289 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-33289 has anti-gram-positive and anti-gram-negative activities. Alternative Names: Antibiotic FR 33289; (R)-(3-(Acetylhydroxyamino)-2-hydroxypropyl)phosphonic acid. CAS No. 73240-15-0. Molecular formula: C5H12NO6P. Mole weight: 213.13.
FR 65814
FR 65814 is originally isolated from Penicillum jensenii F-2883. It has a strong immunosuppressive effect, and the IC50 of inhibiting mixed lymphocyte reaction (MLR) in mice is 34 nmol/L. Alternative Names: 4-(2-Methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2.5)octane-5,6-diol. CAS No. 103470-60-6. Molecular formula: C15H24O4. Mole weight: 268.35.
FR 66979
FR 66979 is produced by the strain of Streptomyces sandaensis No. 6897. It has inhibitory activity against tumor cells, including leukemia P388 cells and melanoma B16 cells. Alternative Names: [7,9-Dihydroxy-5-(hydroxymethyl)-1,1a,2,8,9,9a-hexahydro-3,9-epoxyazireno[2,3-c][1]benzazocin-8-yl]methyl hydrogen carbonimidate. Grades: 97%. CAS No. 102409-60-9. Molecular formula: C14H17N3O6. Mole weight: 323.30.
FR-900098
FR-900098 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-900098 has anti-gram-positive and anti-gram-negative activities. Alternative Names: Antibiotic FR-900098; FR 900098; BRN 2096083; 3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid. Grades: >98%. CAS No. 66508-32-5. Molecular formula: C5H12NO5P. Mole weight: 197.13.
FR 900109
It is produced by the strain of Streptomyces prunicolor. FR 900109 has anti-gram-positive bacteria activity. Alternative Names: Antibiotic FR900109; FR900109. CAS No. 83512-61-2. Molecular formula: C27H32O9. Mole weight: 500.54.
FR 900130
FR 900130, isolated from Streptomyces catenulae, is an antibiotic easily to decompose. It has anti-gram-positive and anti-gram-negative activities, and has a synergistic effect with D-cycloserine. Alternative Names: L-2-amino-3-butynoic acid; Antibiotic FR 900130; (S)-2-Amino-3-butynoic acid. Grades: >95%. CAS No. 73537-09-4. Molecular formula: C4H5NO2. Mole weight: 99.09.
FR 900137
FR 900137 is produced by the strain of Streptomyces unzenensis 2050. It has a broad spectrum of antibacterial activity and has a strong effect on Pseudomonas aeruginosa ?. Alternative Names: Antibiotic FR 900137; L-Leucine, 2-(hydroxymethoxyphosphinyl)-2-methylhydrazide; 2-Amino-N-[hydroxy(methoxy)phosphoryl]-N,4-dimethylpentanehydrazonic acid. CAS No. 73706-58-8. Molecular formula: C8H20N3O4P. Mole weight: 253.24.
FR-900148
It is originally isolated from Streptomyces xanthocidicus 301. FR-900148 can inhibit gram-positive and gram-negative bacteria, but has no effect on pseudomonas aeruginosa. CAS No. 73706-57-7. Molecular formula: C10H15ClN2O5. Mole weight: 278.69.
FR 900403
FR 900403 is a nucleoside antibiotic originally isolated from Kernia sp. F-19849. It had anti-Candida activity, and the MIC against Candida albicans FP663 was 0.4 μg/mL. Alternative Names: FR900403; beta-D-Ribofuranuronic acid, 3-((2-amino-3-methyl-1-oxopentyl)amino)-1-(6-amino-9H-purin-9-yl)-1,3-dideoxy-. CAS No. 131206-83-2. Molecular formula: C16H23N7O5. Mole weight: 393.40.
FR 900482
FR 900482 is produced by the strain of Streptomyces sandaensis No. 6897. It is highly sensitive to Bacillus stearothermophilus var. calidolactis C 953 and has anti-P388, B16, EL4, FM3A, L1210, BHK-21 and other cell activities. Alternative Names: Antibiotic FR 900482; BRN 4886722; (5-Formyl-7,9-dihydroxy-1,1a,2,8,9,9a-hexahydro-3,9-epoxyazireno[2,3-c][1]benzazocin-8-yl)methyl hydrogen carbonimidate. CAS No. 102363-08-6. Molecular formula: C14H15N3O6. Mole weight: 321.28.
FR-900490
FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin C. Uses: Fr-900490 is effective in reversing the damage to bone marrow caused by mitomycin c. Alternative Names: FR 900490; FR900490; BMY 28700; BMY28700; BMY-28700; (2S,3R)-2-[(L-Asparaginyl)amino]-3-[[(S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoic acid. Grades: >98%. CAS No. 105424-59-7. Molecular formula: C14H22N6O6. Mole weight: 370.36.
FR 900523
FR 900523, isolated from Streptomyces, suppresses immune response in vitro with IC50 of 1.6 nM for mouse mixed lymphocyte. CAS No. 104987-09-9. Molecular formula: C42H67NO12. Mole weight: 777.98.
FR 900525
FR 900525 is a metabolite produced by the strain of Streptomyces tsukubaensis No. 9993. It has antifungal activity. Alternative Names: BRN 4225908; FR-900525. CAS No. 104987-10-2. Molecular formula: C43H67NO12. Mole weight: 789.99.
FR 901235
This active molecular is an immunoactive substance produced by Paecilomyces carneus F-4882, an imperfect fungus. FR-901235 can lead the mitogen-induced lymphocyte proliferation to go back to a normal level after being suppressed by addition of immunosuppressive factor. Alternative Names: FR-901235; (-)-2,4,9-Trihydroxy-6-methoxy-7-methyl-2-(2-oxopropyl)-1H-phenalene-1,3(2H)-dione. Grades: 95%. CAS No. 124190-19-8. Molecular formula: C18H16O7. Mole weight: 344.31.
FR-901451
It is originally isolated from Flexibacter sp. No. 758. FR-901451 had inhibitory activity against HLE with ID50 of 2.3 X 10-7 mol/L. And it also has inhibitory effects on PPE, chymosin and proteinase. Molecular formula: C61H81N13O18. Mole weight: 1284.37.
FR901459
FR901459, a product of the fungus Stachybotrys chartarum No. 19392, is a derivative of cyclosporin A (CsA) and a powerful immunosuppressant that binds cyclophilin. Its immunosuppressive effect was lower than that of cyclostatin A. CAS No. 155144-72-2. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
FR-901463
FR-901463 is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Alternative Names: FR 901463; FR901463; WB 2663A. CAS No. 146478-74-2. Molecular formula: C27H42ClNO8. Mole weight: 544.1.
FR-901464
It is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Alternative Names: Fr901464; 2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]tetrahydro-2,5-dimethyl-2H-pyran-3-yl]-, (2Z,4S)-; WB 2663B; Antibiotic WB 2663B; Antibiotic FR 901464. Grades: 90%. CAS No. 146478-72-0. Molecular formula: C27H41NO8. Mole weight: 507.62.
FR-901465
FR-901465 is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Alternative Names: FR 901465; FR901465; WB 2663C. CAS No. 146478-73-1. Molecular formula: C27H41NO9. Mole weight: 523.6.
FR901469
FR901469 is an antifungal antibiotic produced by fungal sp. No. 11243. It inhibits the activity of 1, 3-β-glucan synthase, and has strong anti-Candida albicans and Aspergillus fumigatus activity in vitro and in vivo. Alternative Names: FR-901469; Lipopeptidolactone FR901469. Molecular formula: C71H116N14O23. Mole weight: 1533.76.
FR901483
FR901483 is originally isolated from Cladotryum sp. No. 11231. It has a strong immunosuppressive effect. Molecular formula: C20H31N2O6P. Mole weight: 426.44.
FR901512
FR901512, a new specific inhibitor of HMG-CoA reductase, is isolated from the culture of an agonomycetous fungus No. 14919. FR901512 inhibits cholesterol synthesis from [14C] acetate in Hep G2 cells. Alternative Names: 6-Heptenoic acid, 7-[(6R,8S)-8-(acetyloxy)-5,6,7,8-tetrahydro-2,6-dimethyl-1-naphthalenyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,E)-7-((6R,8S)-8-acetoxy-2,6-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-3,5-dihydroxyhept-6-enoic acid. CAS No. 151606-25-6. Molecular formula: C21H28O6. Mole weight: 376.44.
FR 901537
FR-901537, a naphthothiazin compound, has been found to be an aromatase inhibitor that could be used as a cytostatic antibiotic and was once studied in breast cancer. Alternative Names: FR-901537; FR901537; (R)-N-(3-((2-((2,3-Dihydro-6-hydroxy-2-oxo-1H-naphtho(2,1-b)(1,4)thiazin-5-yl)thio)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide. Grades: 98%. CAS No. 161162-21-6. Molecular formula: C23H29N3O6S2. Mole weight: 507.62.
Fragilomycin A
Fragilomycin A is produced by the strain of Streptosporangium fragilis SK & F-BC2496. It has anti-gram-negative bacteria and anaerobic bacteria activity. Molecular formula: C54H82N2O26. Mole weight: 1175.22.
Fredericamycin A
Produced by the strain of Streptomyces griseus (FCRC-48), Fredericamycin A has anti-gram-positive bacterial and fungal activity, and shows strong anti-tumor effect in vivo and in vitro. Alternative Names: Fcrc-A48; NSC-305263; (S)-6',7'-Dihydro-4,9,9'-trihydroxy-6-methoxy-3'-[(1E,3E)-1,3-pentadienyl]spiro[2H-benz[f]indene-2,8'-[8H]cyclopent[g]isoquinoline]-1,1',3,5,8(2'H)-pentone; 4',9,9'-trihydroxy-6'-methoxy-3-[(1E,3E)-penta-1,3-dienyl]spiro[6,7-dihydro-2H-cyclopenta[g]isoquinoline-8,2'-cyclopenta[g]naphthalene]-1,1',3',5',8'-pentone. CAS No. 80455-68-1. Molecular formula: C30H21NO9. Mole weight: 539.49.
Frenolicin
Frenolicin is produced by the strain of Streptomyces fradiae. It has anti-gram-positive bacterial and fungal (weak) activity. Alternative Names: Frenolicine; (1R,3S,4aS,10aR)-3,4,5,10-Tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-4a,10a-epoxy-1H-naphtho(2,3-C)pyran-3-acetic acid. CAS No. 10023-07-1. Molecular formula: C18H18O7. Mole weight: 346.33.
Frenolicin B
One of the antibiotics produced by the strain of Streptomyces roseofulvus AM-3876. It has antifungal and mycoplasma activities. Alternative Names: (3aR,5R,11bR)-7-hydroxy-5-propyl-3,3a,5,11b-tetrahydro-2H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione; (1R)-1β-Propyl-3,4,5,10-tetrahydro-4α,9-dihydroxy-5,10-dioxo-1H-naphtho[2,3-c]pyran-3α-acetic acid 3,4-lactone. CAS No. 68930-68-7. Molecular formula: C18H16O6. Mole weight: 328.32.
Frequentin
Produced by the strain of Penicillum frequentans and Pen. palitans, Frequentin has the activity of resisting ear mold, mucor mold, ploughshare mold and aspergillus. Alternative Names: Frequentine; 6-[(1E,3E)-hepta-1,3-dienyl]-3,4-dihydroxy-2-oxocyclohexane-1-carbaldehyde; 6-hepta-1,3-dienyl-3,4-dihydroxy-2-oxocyclohexane-1-carbaldehyde. Grades: >98%. CAS No. 29119-03-7. Molecular formula: C14H20O4. Mole weight: 252.31.
Friulimicin A
An antibiotic originally isolated from Actinoplanes friuliensis sp. HAG 010964. Friulimicin A has the activity of inhibiting the synthesis of peptidoglycan. It is a naturally occurring cyclic lipopeptide, with excellent activity against gram-positive pathogens through cell wall interruption, including multidrug-resistant strains. Molecular formula: C58H92N14O19. Mole weight: 1289.43.
Friulimicin B
An antibiotic originally isolated from Actinoplanes friuliensis sp. HAG 010964. Friulimicin B has the activity of inhibiting the synthesis of peptidoglycan. It is a naturally occurring cyclic lipopeptide, with excellent activity against gram-positive pathogens through cell wall interruption, including multidrug-resistant strains. Alternative Names: Friulimycin B; 2,2'-((6S,9R,15S,21S,24S,26aR,33S,34S,36aS)-33-((S)-4-amino-2-((Z)-12-methyltridec-3-enamido)-4-oxobutanamido)-9-((R)-1-aminoethyl)-24-((S)-1-carboxyethyl)-6-isopropyl-34-methyl-5,8,11,14,17,20,23,26,32,36-decaoxotetratriacontahydro-1H,5H-pyrido[1,2-a]pyrrolo[1,2-y][1,4,7,10,13,16,19,22,25,28]decaazacyclohentriacontine-15,21-diyl)diacetic acid. Grades: >98%. CAS No. 239802-15-4. Molecular formula: C59H94N14O19. Mole weight: 1303.48.
Fudecalone
It is produced by the strain of Penicillum sp. FO-2030. Fudecalone completely inhibited Eimeria Tenella, a coccidius resistant to Monesin, at a concentration of 16 μmol/L. Molecular formula: C15H22O3. Mole weight: 250.33.
Fujianmycin A
It is produced by the strain of Streptomyces sp. Fujianmycin A has anti-subtilis activity. Alternative Names: (3s,4r)-4,8-dihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2h)-trione; O-Demethylrubiginone A2; 4,8-Dihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. CAS No. 96695-57-7. Molecular formula: C19H14O5. Mole weight: 322.31.
Fujianmycin B
It is produced by the strain of Streptomyces sp. Fujianmycin B requires a high concentration to show its activity. Alternative Names: Rubiginone A2; (3s,4r)-4-hydroxy-8-methoxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2h)-trione; 4-Hydroxy-8-methoxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. CAS No. 130548-09-3. Molecular formula: C20H16O5. Mole weight: 336.34.
Fulgidin
It is the isomeric lichen depsidone of isofulgidin isolated from the lichen Rinodina dissa. Alternative Names: 2,4,7-trichloro-3-hydroxy-8-methoxy-1,6-dimethyl-dibenzo[b,e][1,4]dioxepin-11-one; Isofulgidin; 11H-dibenzo[b,e][1,4]dioxepin-11-one, 2,4,7-trichloro-3-hydroxy-8-methoxy-1,6-dimethyl-. CAS No. 71339-43-0. Molecular formula: C16H11Cl3O5. Mole weight: 389.61.
Fulvoferruginin
Fulvoferruginin is produced by the strain of Marasmius fuloferrugineus. It showed cytotoxicity and antifungal activity, especially to Paecilomyces varioti with MIC of 1-5 μg/mL. Molecular formula: C15H18O3. Mole weight: 246.30.
Fulvoplumierin
Fulvoplumierin is produced by the strain of Plumeria acutifolia. Alternative Names: Plumiera rubra; 7-[(1E,2E)-2-Butenylidene]-1,7-dihydro-1-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester. Grades: >98%. CAS No. 20867-01-0. Molecular formula: C14H12O4. Mole weight: 244.24.
Fumaramidmycin
An antibiotic originally isolated from Streptomyces kurssanovii NR-7GG1. It has the activity against gram-positive bacteria and negative bacteria (individual). Alternative Names: Antibiotic C 9154; trans-N-(Phenylacetyl)-2-butenediamide; Ro 09-0049; N1-(2-phenylacetyl)fumaramide. Grades: ≥98%. CAS No. 57687-92-0. Molecular formula: C12H12N2O3. Mole weight: 232.23.
Fumarprotocetraric acid
Fumarprotocetraric acid is originally isolated from Cetraria islandica. Alternative Names: Fumarylprotocetraric acid; NSC-249984; NCGC00095467-02; [(7-carboxy-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-9-yl)methyl] hydrogen fumarate. Grades: >95%. CAS No. 489-50-9. Molecular formula: C22H16O12. Mole weight: 472.35.
Fumarylcarboxyamido-L-2,3-diaminopropionyl-L-alanine is produced by the strain of Streptomyces collinus A-19006. It has antifungal and trichomonas effects. Alternative Names: L-Ala-3-[[(E)-4-Amino-1,4-dioxo-2-butenyl]amino]-L-Ala-OH. Molecular formula: C10H16N4O5. Mole weight: 272.26.
Fumaryl-DL-alanine
It is produced by the strain of Penicillum resticulosum. It has anti-gram-positive bacterial activity. Molecular formula: C7H9NO5. Mole weight: 187.15.
Fumifungin
Fumifungin is produced by the strain of Aspergollus fumigatus Fresenius 1863. It has the antifungal activities of Cercospora, Cladosporium, Aspergillus niger, Penicillium digitatum, Trichophyton mentagrophytes, Alternaria, Candida albicans and yeast. Alternative Names: 2-Amino-4-acetoxy-3,5,14-trihydroxyeicosenoic acid. CAS No. 110231-33-9. Molecular formula: C22H41NO7. Mole weight: 431.56.
Fumigatin
Fumigatin is produced by the strain of Aspergillus fumigatus. It has anti-gram-positive bacteria, negative bacteria (weak) and vibrio cholerae activities. Alternative Names: 2-hydroxy-3-methoxy-6-methyl-1,4-benzoquinone; 3-Hydroxy-2-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione. CAS No. 484-89-9. Molecular formula: C8H8O4. Mole weight: 168.15.
Fumiquinazoline D
Fumiquinazoline D is a fungal metabolite originally isolated from Aspergillus fumigatus. It has activity against Gram-positive and Gram-negative bacteria as well as F. solani and C. albicans fungi. It's a cytotoxin agent. Alternative Names: (1'R,2S,3'S,5'S,9aS)-1,4',5',9a-tetrahydro-1',2-dimethyl-spiro[9H-imidazo[1,2-a]indole-9,3'-[1,5](iminomethano)[3H][1,4]oxazepino[3,4-b]quinazoline]-3,7',13'(1'H,2H)-trione. Grades: ≥95%. CAS No. 140715-86-2. Molecular formula: C24H21N5O4. Mole weight: 443.45.
Fumitremorgin B
Fumitremorgin B is a natural compound isolated from the fermentation broth of Aspergillus fumigatus LN-4. Fumitremorgin B is a tremorgenic mycotoxin that is active against the phytopathogenic fungi. It has antifeedant activity against armyworm (M. separata) larvae when applied to fresh wheat leaves. Alternative Names: Lanosulin; 5H,14H-Pyrrolo(1'',2'':4',5')pyrazino(1',2':1,6)pyrido(3,4-b)indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-butenyl)-12-(2-methyl-1-propenyl)-, (5aR-(5a-alpha,6-alpha,12-beta,14a-alpha))-. Grades: 98.5%. CAS No. 12626-17-4. Molecular formula: C27H33N3O5. Mole weight: 479.57.
Fumonisin B2
Fumonisin B2 is a liver toxin produced by Gibberella fujikuroi and Fumarium moniliforme. It is more cytotoxic than fumonisin B1. Fumonisin B2 inhibits sphingosine acyltransferase. Uses: Carcinogens, environmental. Alternative Names: 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-9,11-dihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester. Grades: >95%. CAS No. 116355-84-1. Molecular formula: C34H59NO14. Mole weight: 705.85.
Fumonisin B3
Fumonisin B3 is a mycotoxin produced by Fusarium moniliforme which is the most commonly reported fungal species infecting maize. Fumonisins acts as an inhibitor of ceramide synthase (sphingosine N-acyltransferase). Alternative Names: FB3; (2R,2'R)-2,2'-((((5R,6R,7S,9S,11R,18S,19S)-19-Amino-11,18-dihydroxy-5,9-dimethylicosane-6,7-diyl)bis(oxy))bis(2-oxoethane-2,1-diyl))disuccinic Acid. Grades: ≥98%. CAS No. 1422359-85-0. Molecular formula: C34H59NO14. Mole weight: 705.83.
Funalenone
Funalenone is a phenalene compound originally isolated from A. niger. It inhibits HIV-1 integrase and type I collagenase. Funalenone is also a selective inhibitor of matrix metalloproteinase-1 (MMP-1; IC50 = 170 μM). Alternative Names: 8-deoxyxanthoherquein; 3,4,7,9-tetrahydroxy-2-methoxy-6-methyl-1H-phenalen-1-one. Grades: ≥95%. CAS No. 259728-61-5. Molecular formula: C15H12O6. Mole weight: 288.25.
Fungichromin
A pentaene antifungal produced by streptomyces; exhibits broad spectrum antifungal and antitumor activity and, like filipin, acts via interaction with cell membrane sterols. Alternative Names: Cogomycin; Pentamycin; Lagosin; 14-Hydroxyfilipin; Antibiotic A-246; NSC-105388. Grades: >95% by HPLC. CAS No. 6834-98-6. Molecular formula: C35H58O12. Mole weight: 670.83.
Furanocandin
Furanocandin is originally isolated from Tricothecium sp. It is highly active against candida fungi with MIC of 0.20-1.56 μg/mL. Alternative Names: 2,4-dihydroxy-6-(hydroxymethyl)phenyl 4-O-{6-O-[(2E,4Z)-8-hydroxydeca-2,4-dienoyl]-beta-D-galactofuranosyl}-3-O-[(2E,4E,8E,10E)-7-hydroxyhexadeca-2,4,8,10-tetraenoyl]-beta-D-glucopyranoside. Molecular formula: C45H64O18. Mole weight: 892.98.
Furanomycin
It can resist gram-positive and negative bacteria and inhibit the bacteriophage of Escherichia coli. It is also a L-isoleucine competitive antagonist. Alternative Names: L-(+)-furanomycin; NSC 116328; (5S,2R,αS)-α-Amino-2,5-dihydro-5-methyl-2-furanacetic acid; L-xylo-Hept-4-enonic acid, 2-amino-3,6-anhydro-2,4,5,7-tetradeoxy-. Grades: 95%. CAS No. 18455-25-9. Molecular formula: C7H11NO3. Mole weight: 157.17.
Furaquinocin A
Furaquinocin A is originally isolated from Streptomyces sp. KO-3988. It can kill HeLa S3 and B16 melanoma cells, but has no antibacterial activity. Alternative Names: (2R)-2α,3,8-Trimethyl-3α-[(1R,3Z)-1,5-dihydroxy-4-methyl-3-pentenyl]-4-hydroxy-7-methoxy-2,3,6,9-tetrahydronaphtho[1,2-b]furan-6,9-dione; 3-(1,5-Dihydroxy-4-methyl-3-pentenyl)-2,3-dihydro-4-hydroxy-7-methoxy-2,3,8-trimethylnaphtho(1,2-b)furan-6,9-dione. CAS No. 125108-66-9. Molecular formula: C22H26O7. Mole weight: 402.44.
Furaquinocin B
Furaquinocin B is originally isolated from Streptomyces sp. KO-3988. It can kill HeLa S3 and B16 melanoma cells, but has no antibacterial activity. Alternative Names: Naphtho(1,2-B)furan-6,9-dione, 3-(1,5-dihydroxy-4-methyl-3-pentenyl)-2,3-dihydro-4-hydroxy-7-methoxy-2,3,8-trimethyl-; (2R)-2α,3,8-Trimethyl-3α-[(1R,3E)-1,5-dihydroxy-4-methyl-3-pentenyl]-4-hydroxy-7-methoxy-2,3,6,9-tetrahydronaphtho[1,2-b]furan-6,9-dione. CAS No. 125224-54-6. Molecular formula: C22H26O7. Mole weight: 402.44.
Furaquinocin C
Furaquinocin C is originally isolated from Streptomyces sp. KO-3988. It can kill HeLa S3 and B16 melanoma cells, but has no antibacterial activity. Alternative Names: Furaquinocin C3; 4-hydroxy-7-methoxy-2,3,8-trimethyl-3-(4-methylpent-3-en-1-yl)-2,3-dihydronaphtho[1,2-b]furan-6,9-dione; Naphtho(1,2-b)furan-6,9-dione, 2,3-dihydro-4-hydroxy-7-methoxy-2,3,8-trimethyl-3-(4-methyl-3-pentenyl)-. CAS No. 134984-98-8. Molecular formula: C22H26O5. Mole weight: 370.44.
Furazolidone
Furazolidone is an antimicrobial agent used for the treatment of bacterial and protozoal infections. Alternative Names: Nitrofurazolidone; Nitrofuroxon. Grades: 98.0%. CAS No. 67-45-8. Molecular formula: C8H7N3O5. Mole weight: 225.16.