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L-Valine-[3-d]
L-Valine-[3-d] is a deuterium labelled analogue of L-Valine. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. Grade: 98% by CP; 98% atom D. Molecular formula: C5H10DNO2. Mole weight: 118.15.
L-Valine-[d8]
L-Valne-[d8] is a labelled L-Valine. Valine is a branched-chain amino acid used in the protein biosynthesis. It is essential for animals with insulin-resistant property. Synonyms: (S)-α-Aminoisovaleric acid-2,3,4,4,4,5,5,5-d8; Deuterated L-valine; L-2-Amino-3-methylbutanoic acid-2,3,4,4,4,5,5,5-d8. Grade: 95% by HPLC; 98% atom D. CAS No. 35045-72-8. Molecular formula: C5H3D8NO2. Mole weight: 125.2.
L-Valine-[d8,13C5,15N]
L-Valine-[d8,13C5,15N] is a 13C & 15N labelled analogue of Valine. L-valine is a branched-chain essential amino acid (BCAA) that has stimulant activity. It promotes muscle growth and tissue repair. Grade: 98% by CP; 97% atom 13C; 97% atom 15N. CAS No. 1994261-62-9. Molecular formula: [13C]5H3D8[15N]O2. Mole weight: 131.15.
L-Valine-[d8,15N]
L-Valine-[d8,15N] is a 15N & deuterium labelled analogue of L-Valine. L-valine is a branched-chain essential amino acid (BCAA) that has stimulant activity. It promotes muscle growth and tissue repair. Grade: 98% by CP; 96% atom 15N. Molecular formula: C5H3D8[15N]O2. Mole weight: 126.19.
L-Valine-[dimethyl-13C2]
L-Valine-[dimethyl-13C2] is a 13C labelled analogue of L-valine, which is a branched-chain essential amino acid (BCAA) that has stimulant activity. It promotes muscle growth and tissue repair. Grade: 98% by CP; 99% atom 13C. Molecular formula: C3[13C]2H11NO2. Mole weight: 119.13.
L-Valine-N-Boc-[1-13C]
L-Valine-N-Boc-[1-13C] is a 13C labelled analogue of N-Boc-L-valine, which is used in the multi-peptide synthesis and serves as the amino acid protection monomer. Synonyms: tert-Butoxycarbonylvaline-1-13C; Boc-Val-OH-1-13C. Grade: 98% by CP; 99% atom 13C. CAS No. 286460-61-5. Molecular formula: C9[13C]H19NO4. Mole weight: 218.25.
L-Valine-N-Boc-[13C5,15N]
L-Valine-N-Boc-[13C5,15N] is a 13C & 15N labelled analogue of N-Boc-L-valine. N-Boc-L-valine is used in the multi-peptide synthesis and serves as the amino acid protection monomer. Synonyms: tert-Butoxycarbonylvaline-13C5,15N; Boc-Val-OH-13C5,15N. Grade: 98% by CP; 97% atom 13C; 97% atom 15N. Molecular formula: C5[13C]5H19[15N]O4. Mole weight: 223.22.
L-Valine-N-Fmoc-[1-13C]
L-Valine-N-Fmoc-[1-13C] is a 13C labelled analogue of Fmoc-valine. Fmoc-valine is a sterically hindered, Fmoc-protected amino acid and is a derivative of L-Valine. Fmoc-valine is commonly used to synthesize 4-thiazolidinones and 4-metathiazanones as well. Synonyms: Fmoc-Val-OH-1-13C; (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl(1-13C)butanoic acid; N-(9-Fluorenylmethoxycarbonyl)-L-valine-1-13C. Grade: 98% by CP; 99% atom 13C. CAS No. 286460-74-0. Molecular formula: C19[13C]H21NO4. Mole weight: 340.38.
L-Valine-N-Fmoc-[13C5]
L-Valine-N-Fmoc-[13C5] is a 13C labelled analogue of Fmoc-valine. Fmoc-valine is a sterically hindered, Fmoc-protected amino acid and is a derivative of L-Valine. Fmoc-valine is commonly used to synthesize 4-thiazolidinones and 4-metathiazanones as well. Synonyms: Fmoc-Val-OH-13C5. Grade: 98% by CP; 97% atom 13C. Molecular formula: C15[13C]5H21NO4. Mole weight: 344.35.
L-Valine-N-Fmoc-[13C5,15N]
L-Valine-N-Fmoc-[13C5,15N] is a 13C & 15N labelled analogue of Fmoc-Val-OH, which is a Fmoc protected valine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Synonyms: Fmoc-Val-OH-13C5,15N. Grade: 98% by CP; 99% atom 13C; 98% atom 15N. Molecular formula: C15[13C]5H21[15N]O4. Mole weight: 345.34.
L-Valine-N-Fmoc-[15N]
L-Valine-N-Fmoc-[15N] is a 15N labelled analogue of Fmoc-Val-OH, which is a Fmoc protected valine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Synonyms: Fmoc-Val-OH-15N. Grade: 98% by CP; 998% atom 15N. Molecular formula: C20H21[15N]O4. Mole weight: 340.38.
L-Xylose-[1-13C]
L-Xylose-[1-13C] is an isotope labelled form of L-Xylose. Xylose is classified as a monosaccharide of the aldopentose type, L-Xylose shows anti-viral activites against herpes simplex virus 1 & 2 as well as influenza A virus. Synonyms: L-xylose-1-13C; L-[1-13C]xylo-pentose. CAS No. 178101-87-6. Molecular formula: C4[13C]H10O5. Mole weight: 151.12.
L-xylose-[1,2-13C2]
L-xylose-[1,2-13C2] is a labelled analogue of L-xylose, which is the levo-isomer of Xylose. Synonyms: L-[1,2-13C2]xylose; L-xylose-1,2-13C2. Molecular formula: C3[13C]2H10O5. Mole weight: 152.12.
L-Xylose-[2-13C]
L-Xylose-[2-13C] is an isotope labelled form of L-Xylose. Xylose is classified as a monosaccharide of the aldopentose type, L-Xylose shows anti-viral activites against herpes simplex virus 1 & 2 as well as influenza A virus. Synonyms: L-xylose-2-13C; L-[2-13C]xylo-pentose. CAS No. 478506-63-7. Molecular formula: C4[13C]H10O5. Mole weight: 151.12.
L-xylose-[5-13C]
L-xylose-[5-13C] is a labelled analogue of L-xylose, which is the levo-isomer of Xylose. Synonyms: L-[5-13C]xylose; L-[5-13C]xylo-pentose; L-xylose-5-13C. CAS No. 478506-64-8. Molecular formula: C4[13C]H10O5. Mole weight: 151.12.
L-xylose-[UL-13C5]
L-xylose-[UL-13C5] is a labelled analogue of L-xylose, which is the levo-isomer of Xylose. Synonyms: L-[UL-13C5]xylose; L-[UL-13C5]xylo-pentose; L-xylose-U-13C5. Molecular formula: [13C]5H10O5. Mole weight: 155.10.
(-)-LY-338979
(-)-LY-338979 is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-2-(4-(2-((R)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; (4-(2-((R)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid; N-(4-{2-[(5R)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[2-[(5R)-2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-. Molecular formula: C20H21N5O7. Mole weight: 443.41.
(+)-LY-338979
(+)-LY-338979 is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-2-(4-(2-((S)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; (4-(2-((S)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid; N-(4-{2-[(5S)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[2-[(5S)-2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-. Molecular formula: C20H21N5O7. Mole weight: 443.41.
(±)-LY 367385
(±)-LY367385 is a selective mGlu1a antagonist. Synonyms: 4-[Amino(carboxy)methyl]-3-methylbenzoic acid; LY 367385; LY-367385; LY367385. Grade: 98%. CAS No. 198419-90-8. Molecular formula: C10H11NO4. Mole weight: 209.2.
(±)-LY 395756
(±)-LY 395756 is a mixed mGlu2 agonist/mGlu3 antagonist. Synonyms: LY 395756; LY395756; LY-395756; (1S,2S,4R,5R,6S)-rel-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid. Grade: ≥98% by HPLC. CAS No. 852679-66-4. Molecular formula: C9H13NO4. Mole weight: 199.21.
(±)-LY 426965 dihydrochloride
(±)-LY 426965 dihydrochloride is a selective 5-HT1A antagonist. Synonyms: (±)-LY 426965 dihydrochloride; (±)-LY426965 dihydrochloride; (±)-LY-426965 dihydrochloride; 1-Cyclohexyl-4-[4-(2-methoxyphenyl)-1-piperazinyl]-2-methyl-2-phenyl-1-butanone dihydrochloride. Grade: 99%. CAS No. 228418-81-3. Molecular formula: C28H38N2O2.2HCl. Mole weight: 507.54.
Lymecycline-[d8]
Lymecycline-[d8] is the labelled analogue of Lymecycline, which is a tetracycline broad-spectrum antibiotic. Synonyms: N6-[[[[(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl]carbonyl]amino]methyl]-L-lysine-d8; Armyl-d8; Ciclisin-d8; Ciclolysal-d8; Ciclolysine-d8; Infaciclina-d8; Lisinbiotic-d8; Lisinciclina-d8; Mucomycin-d8; N-Lysinomethyltetracycline-d8; Tetramyl-d8; Lymecycline-d8. Grade: 95% by HPLC; 98% atom D. Molecular formula: C29H30D8N4O10. Mole weight: 610.68.
Lynestrenol
Lynestrenol is a synthetic progestational hormone that acts as an agonist of the progesterone receptor. It has been used as a progestin medication. Synonyms: Ethinylestrenol; (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol. Grade: 98.0%. CAS No. 52-76-6. Molecular formula: C20H28O. Mole weight: 284.44.
(+)-Lyoniresinol-3a-O-(6''-3,5-dimethoxy-4-hydroxybenzoyl)-b-D-glucopyranoside, a remarkable biomedicine of immense research interest, demonstrates profound therapeutic potential for tackling diverse ailments. Renowned for its exceptional antioxidant and anticancer properties, this compound stands as a promising contender for revolutionizing cancer therapy. Excitingly, it exhibits remarkable efficacy against breast, lung, and colon cancers, yielding new hope for patients. Moreover, its significance extends beyond oncology, showing promise in addressing cardiovascular and neurological disorders. As the biomedical industry ardently pursues comprehensive investigations, the true transformative power of this compound awaits profound unveiling.
(+)-Lyoniresinol-3a-O-(6''-3-methoxy-4-hydroxybenzoyl)-b-D-glucopyranoside, a remarkable and influential bioactive molecule, finds extensive application in the realm of biomedical science. Its versatility in combating an array of ailments, including cancer and inflammation, positions it as an exceptional entity within the pharmaceutical domain. Embracing an intricate mode of action and revealing remarkable therapeutic potential, this multifaceted compound emerges as a highly coveted candidate for intricate cancer treatments and the alleviation of inflammatory manifestations. Through its profound mechanisms and prospective medical implications, this invaluable asset revolutionizes the landscape of biomedicine.
M2-Nitrodienamine
Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C14H24N2O2. Mole weight: 252.32.
M3-Nitrodienamine
Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C17H22N2O2. Mole weight: 286.37.
M4-Nitrodienamine
Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C13H20N2O2. Mole weight: 236.31.
M5-Nitrodienamine
Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C17H24N2O2. Mole weight: 288.38.
Mabuterol-[d9] hydrochloride
Mabuterol-[d9] hydrochloride is the labelled analogue of Mabuterol hydrochloride, which is an acidic salt of Mabuterol. Mabuterol is a β2-adrenergic agonist, used as a bronchodilator/antiasthmatic. Synonyms: 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert-butyl-D9-amino-ethanol hydrochloride; Mabuterol-D9 hydrochloride; 1-(4-Amino-3-chloro-5-(trifluoromethyl)phenyl)-2-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)amino)ethan-1-ol Hydrochloride; Mabuterol-(tert-butyl-d9) hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1353867-83-0. Molecular formula: C13H9D9ClF3N2O.HCl. Mole weight: 356.26.
Macitentan-[d4]
Macitentan-[d4] is the labelled analogue of Macitentan. Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Macitentan D4; N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propyl-Sulfamide d4. Grade: 98% by HPLC; 98% atom D. CAS No. 1258428-05-5. Molecular formula: C19H16D4Br2N6O4S. Mole weight: 592.30.
Malachite Green-[d5] Picrate
Malachite Green-[d5] Picrate is the labelled analogue of Malachite Green, which is used as a dyestuff as well as an antimicrobial in aquaculture. Synonyms: Malachite Green D5 Picrate. Grade: 95% by HPLC; 98% atom D. CAS No. 1258668-21-1. Molecular formula: C29H22D5N5O7. Mole weight: 562.59.
Maleic acid-[2,3-13C2]
Labelled Maleic acid. Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxylgroups. Maleic acid is the cis-isomer of butenedioic acid, whereas fumaric acid is the trans-isomer. It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, and maleic acid has few applications. Synonyms: (E)-but-2-enedioicacid; Maleicacid-2,3-13C2; Fumaricacid-2,3-13C2; 490180_ALDRICH; 123548-45-8; 769108-94-3. Grade: 99% by CP; 99% atom 13C. CAS No. 123548-45-8. Molecular formula: C2[13C]2H4O4. Mole weight: 118.06.
Maleic acid-[2,3-d2]
Labelled Maleic acid. Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxylgroups. Maleic acid is the cis-isomer of butenedioic acid, whereas fumaric acid is the trans-isomer. It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, and maleic acid has few applications. Synonyms: 2-Butenedioic-2,3-d2 Acid. Grade: 98% atom D. CAS No. 24461-33-4. Molecular formula: C4H2D2O4. Mole weight: 118.08.
Maleic anhydride-[2,3-13C2]
Labelled form of Maleic Anhydride. Maleic anhydride is a heterocyclic compound used in the manufacture of unsaturated polyester resins and has a wide range of other applications, for example it can be used in synthetic tensides, insecticides, herbicides and fungicides. Synonyms: 2,5-Furandione-3,4-13C2. Grade: 99% atom 13C. CAS No. 41403-35-4. Molecular formula: C2[13C]2H2O3. Mole weight: 100.04.
Maleic anhydride-[d2]
Labelled form of Maleic Anhydride. Maleic anhydride is a heterocyclic compound used in the manufacture of unsaturated polyester resins and has a wide range of other applications, for example it can be used in synthetic tensides, insecticides, herbicides and fungicides. Synonyms: 2,5-Furandione-3,4-d2. Grade: 98% atom D. CAS No. 33225-51-3. Molecular formula: C4D2O3. Mole weight: 100.07.
Malonic acid-[1,3-13C2]
Labelled Malonic acid. Malonic acid (MA), also known as propanedioic acid, is a dicarboxylic acid. Malonic acid may be used as a cross-linking agent between corn starch and potato starch to improve its mechanical properties. Synonyms: Propanedioic Acid-1,3-13C2; 1,3-Propanedioic Acid-1,3-13C2; Carboxyacetic Acid-1,3-13C2; Dicarboxymethane-1,3-13C2; Methanedicarboxylic Acid-1,3-13C2; NSC 8124-1,3-13C2. CAS No. 99524-14-8. Molecular formula: C[13C]2H4O4. Mole weight: 106.05.
Malonic acid-[13C3]
Malonic acid-[13C3] is a 13C labelled analogue of Malonic Acid, which is a small bioactive molecule that can be used in variuos reactions. Malonic acid-[13C3] is also a useful intermediate for synthesis of 13C labelled compounds. Synonyms: (1,2,3-13C3)propanedioic acid. Grade: 98% by CP; 99% atom 13C. CAS No. 102342-85-8. Molecular formula: [13C]3H4O4. Mole weight: 107.04.
Maltohexaose-[UL-13C36]
Labelled Maltohexaose. Maltohexaose has been used in a study to investigate the production of a thermophilic maltooligosyl-trehalose synthase. Molecular formula: [13C]36H62O31. Mole weight: 1026.58.
Maltopentaose-[UL-13C30]
Labelled Maltopentaose. Maltopentaose is used in a study to investigate glycation and phosphorylation of α-lactalbumin. Molecular formula: [13C]30H52O26. Mole weight: 858.49.
Maltotetraose-[UL-13C24] is a 13C labelled analogue of Maltotetraose, which is a maltooligosaccharide that is used for research and diagnostic purposes. Maltotetraose-[13C2] itself can be also used as a standard in diagnostic purposes. Molecular formula: [13C]24H42O21. Mole weight: 690.39.
An isotope labelled of MAM2201 N-(4-hydroxypentyl). MAM2201 N-(4-hydroxypentyl) is a synthetic cannabinoid (CB) agonist that displays high affinity for CB receptors. Grade: 95% by HPLC; 98% atom D. Molecular formula: C25H19D5FNO2. Mole weight: 394.5.
Manidipine-[d4]
Manidipine-[d4] is the labelled analogue of Manidipine. Manidipine is a calcium channel blocker used as an antihypertensive. Synonyms: Manidipine-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1189656-59-4. Molecular formula: C35H34D4N4O6. Mole weight: 614.74.
Manidipine dihydrochloride
Manidipine is a calcium channel blocker with IC50 of 2.6 nM. It has been used in clinical treatment of hypertension. Uses: Antihypertensive agents. Synonyms: CV-4093; CV 4093; CV4093. Grade: >98%. CAS No. 89226-75-5. Molecular formula: C35H38N4O6·2HCl. Mole weight: 683.62.
Mapenterol-[d11] hydrochloride
Mapenterol-[d11] hydrochloride is the labelled analogue of Mapenterol hydrochloride, which is a related drug of Clenbuterol. Synonyms: 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-(1,1-dimethyl-D6-propyl-D5-amino)-ethanol hydrochloride; Mapenterol-D11 hydrochloride; 4-Amino-3-chloro-α-[[(1,1-dimethylpropyl-d11)amino]methyl]-5-(trifluoromethyl)benzenemethanol Hydrochloride; Mapenterol-(dimethyl-d6, propyl-d5) hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1325559-18-9. Molecular formula: C14H9D11ClF3N2O.HCl. Mole weight: 372.30.
Maraviroc-[d6]
Maraviroc-[d6] is the labelled analogue of Maraviroc. Maraviroc is an antiretroviral medicine developed for the treatment of HIV infecions. Synonyms: Maraviroc D6; 4,4-Difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl-d6)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]cyclohexanecarboxamide. Grade: 95% by HPLC; 95% atom D. CAS No. 1033699-22-7. Molecular formula: C29H35D6F2N5O. Mole weight: 519.7.
Maytansine
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. Synonyms: NSC153858; NSC-153858; NSC 153858; (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-acetyl-N-methyl-L-alaninate. Grade: ≥95%. CAS No. 35846-53-8. Molecular formula: C34H46ClN3O10. Mole weight: 692.2.
Maytansinoid DM4
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N2'-deacetyl-n2'-(4-Mercapto-4-Methyl-1-oxopentyl)-6-MethylMaytansine. Grade: ≥98.0% (HPLC). CAS No. 799840-96-3. Molecular formula: C39H56ClN3O10S. Mole weight: 780.37.
Mc-MMAD
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. Uses: Adcs cytotoxin-linker. Synonyms: Mc MMAD; McMMAD. Grade: >98%. CAS No. 1401963-15-2. Molecular formula: C51H77N7O9S. Mole weight: 964.26.
Mc-MMAE
Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Synonyms: Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grade: ≥98%. CAS No. 863971-24-8. Molecular formula: C49H78N6O10. Mole weight: 911.18.
Mc-MMAF
Mc-MMAF is a protective group-conjugated MMAF, MMAF is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin and it has lower cytotoxic activity than MMAE. Uses: Sgd 1269 is a potent tubulin inhibitor and is a toxin payload in antibody drug conjugate. it is a useful agent for make antibody drug conjugate (adc) for targeted drug delivery. Synonyms: SGD-1269; SGD 1269; SGD1269; mc-MMAF; mcMMAF; L4-MMAF; Maleimidocaproyl-MMAF; Maleimidocaproyl monomethylauristatin F; Mafodotin.((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. Grade: ≥98%. CAS No. 863971-19-1. Molecular formula: C49H76N6O11. Mole weight: 925.18.
(±)-McN 5652
(±)-McN 5652 is a potent, orally active 5-HT uptake inhibitor. McN-5652 is characterized by exceptionally high potency as an inhibitor of the uptake of serotonin by rat brain synaptosomes in vitro (Ki approximately 0.6 nM) and ex vivo (ED50 approximately 2 mg/kg p.o.). (±)-McN 5652 is a potent, selective inhibitor of serotonin reuptake in mammalian brain. It potently potentiates 5-HT-induced effects in vivo following oral administration. Its biological activity resides predominantly in the (+)-enantiomer. Synonyms: (±)-McN 5652; (±)-McN5652; (±)-McN-5652; (6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline. Grade: ≥98% by HPLC. CAS No. 96795-89-0. Molecular formula: C19H21NS. Mole weight: 295.44.
MCPA-[d3]
MCPA-[d3]. Synonyms: MCPA D3; (4-Chloro-2-methylphenoxy-2,?3,?5-d3)?acetic Acid. Grade: 98% atom D. CAS No. 352431-14-2. Molecular formula: C9H6D3ClO3. Mole weight: 203.64.
m-Cresol-[d7]
m-Cresol-[d7]. Synonyms: m-Cresol D7; 3-Methylphenol-d7; 1-Hydroxy-3-methylbenzene-d7; 3-Hydroxytoluene-d7. Grade: 95% atom D. CAS No. 202325-51-7. Molecular formula: C7HD7O. Mole weight: 115.18.
m-Cresol-[d8]
m-Cresol-[d8]. Synonyms: 3-Methylphenol-d8. Grade: 98% by CP; 98% atom D. CAS No. 302911-90-6. Molecular formula: C7D8O. Mole weight: 116.19.
m-Cresol-[methyl-d3]
m-Cresol-[methyl-d3]. Synonyms: m-Cresol-d3 (methyl-d3); 3-(Methyl-d3)-phenol. Grade: 98% atom D. CAS No. 25026-32-8. Molecular formula: C7H5D3O. Mole weight: 111.16.
(-)-MDL 105725
(-)-MDL 105725 is a selective 5-HT2A antagonist, which is a less active metabolite of MDL 100907. Synonyms: (-)-MDL 105725; (-)-MDL105725; (-)-MDL-105725; (S)-3-((1-(4-fluorophenethyl)piperidin-4-yl)(hydroxy)methyl)-2-methoxyphenol. Grade: 98%. CAS No. 311348-81-9. Molecular formula: C21H26FNO3. Mole weight: 359.43.
(+)-MDL 105725
(+)-MDL 105725 is an active metabolite of MDL 100907, which is a selective 5-HT2A antagonist. Synonyms: (+)-MDL 105725; (+)-MDL105725; (+)-MDL-105725; 3-[(R)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]-hydroxymethyl]-2-methoxyphenol. Grade: 99%. CAS No. 189192-18-5. Molecular formula: C21H26FNO3. Mole weight: 359.43.
(±)-MDL 105725
(±)-MDL 105725 is an active metabolite of MDL 100907, which is a 5-HT2A receptor antagonist. Synonyms: (±)-MDL 105725; (±)-MDL105725; (±)-MDL-105725. Grade: 99%. CAS No. 1018473-89-6. Molecular formula: C21H26FNO3. Mole weight: 359.43.
MDV 3100-[d3]
MDV 3100-[d3] is the labelled analogue of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist in LNCaP cells. Synonyms: MDV 3100 D3; 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)benzamide; Enzalutamide-d3. Grade: 95% by HPLC; 95% atom D. CAS No. 1443331-82-5. Molecular formula: C21H13D3F4N4O2S. Mole weight: 467.45.
Mebendazole-amine-[13C6]
Mebendazole-amine-[13C6] is a labelled impurity of Mebendazole. Mebendazole is a broad-spectrum anthelmintic used as a treatment for roundworms. Mebendazole also has the potential to be used as an anti-cancer agent for showing promise in vitro and in mouse models. Synonyms: 2-Amino-5-(benzoyl-13C6)-1H-benzimidazole. Grade: 95% by HPLC; 98% atom 13C. Molecular formula: C8[13C]6H11N3O. Mole weight: 243.31.
Mebendazole-[d3]
Mebendazole-[d3] is the labelled analogue of Mebendazole, which is a broad-spectrum anthelmintic used in the treatment of roundworms. Synonyms: Mebendazole-D3; (5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl-D3 ester; N-(6-Benzoyl-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester-d3; 5-Benzoyl-2-benzimidazolecarbamic Acid Methyl Ester-d3; Bantenol-d3; Besantin-d3; Mebenvet-d3; Mebex-d3; Noverme-d3; Ovitelmin-d3; Pantelmin-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1173021-87-8. Molecular formula: C16H10D3N3O3. Mole weight: 298.31.
Mebeverine Acid-[d5]
Mebeverine Acid-[d5] is the labelled analogue of Mebeverine Acid, which is a metabolite of Mebeverine, an antispasmodic. Synonyms: Mebeverine Acid D5; 4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butanoic Acid-d5. Grade: >95%. CAS No. 2070015-30-2. Molecular formula: C16H20D5NO3. Mole weight: 284.41.
Mebeverine Alcohol-[d5]
Mebeverine Alcohol-[d5] is the labelled analogue of Mebeverine Alcohol, which is a metabolite of Mebeverine, an antispasmodic. Synonyms: Mebeverine Alcohol D5; 4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-1-butanol-d5; 4-[Ethyl[2-(p-methoxy-α-phenyl)-1-methylethyl]amino]-1-butanol-d5. Grade: >98%. CAS No. 2070015-15-3. Molecular formula: C16H22D5NO2. Mole weight: 270.43.
Mebeverine-[d6] Hydrochloride
Mebeverine-[d6] Hydrochloride is the labelled analogue of Mebeverine, which is an antimuscarinic. Uses: The isotope labelled mebeverine hydrochloride. Synonyms: Mebeverine D6 Hydrochloride; 3,4-(Dimethoxy-d6)benzoic Acid 4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl Ester Hydrochloride; 4-[Ethyl(p-(methoxy-d6)-α-methylphenethyl)amino]veratric Acid Butyl Ester Hydrochloride. Grade: 98% by HPLC; 98% atom D. CAS No. 1329647-20-2. Molecular formula: C25H30D6ClNO5. Mole weight: 472.05.
Meclofenamic acid-[13C6]
Meclofenamic acid-[13C6] is the labelled analogue of Meclofenamic acid. Meclofenamic Acid is a non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It is used to treat muscular pain, joint, arthritis and dysmenorrhea. It is also a COX inhibitor and inhibits prostaglandin biosynthesis. Synonyms: Meclofenamic acid 13C6; 2-(2,6-Dichloro-3-methylphenylamino)-13C6-benzoic acid; N-(3-Methyl-2,6-dichlorophenyl)anthranilic Acid-13C6; Arquel-13C6. Grade: 95% by HPLC; 98% atom 13C. Molecular formula: C9[13C]6H11NO2. Mole weight: 302.10.