BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Zearalenone-14-O-β-glucoside-13C6 is a labelled impurity of Zearalenol. Zearalenol, a resorcylic acid lactones derivative, could be produced by Fusarium fungi in grains and has been found to be an environmental contaminant. Synonyms: (3S)-16-Hydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecine-1,7-dione-14-O-β-D-glucopyranoside-13C. Grade: 95% by HPLC; 98% atom 13C. Molecular formula: 13C6C18H32O10. Mole weight: 486.5.
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo. Uses: Anti-hiv agents; antimetabolites; antimetabolites, antineoplastic; reverse transcriptase inhibitors. Synonyms: 3'-Azido-3-deoxythymidine; AZT; BWA509U; BWA 509U; BWA-509U; ZDV; Azidothymidine; Retrovir; Timazid; NSC 602670; 3'-Azido-2',3'-dideoxythymidine; 1-(3-Azido-2,3-dideoxy-β-D-glycero-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidin-2,4(1H,3H)-dione; 1-(3-Azido-2,3-dideoxy-β-D-ribofuranosyl)thymine. Grade: ≥95%. CAS No. 30516-87-1. Molecular formula: C10H13N5O4. Mole weight: 267.24.
Zidovudine Glucuronide-[13C6]
One of the isotopic labelled impurities of Zidovudine, which is a reverse transcriptase inhibitor and could restrain the HIV-1 replication. Synonyms: (2S,3S,4S,5R)-6-[[(2S)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid-13C6. Molecular formula: C10[13C]6H21N5O10. Mole weight: 449.30.
Zileuton
Zileuton is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used to decrease the symptoms of asthma. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: A-64077; A64077; A 64077; Zileuton; trade name ZYFLO; ZYFLO CR. Grade: >98%. CAS No. 111406-87-2. Molecular formula: C11H12N2O2S. Mole weight: 236.29.
Zileuton-[d4]
Zileuton-[d4] is the labelled analogue of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: Zileuton D4; N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1189878-76-9. Molecular formula: C11H8D4N2O2S. Mole weight: 240.31.
Zilpaterol-[d7]
One of the isotopic labelled form of Zilpaterol, which is a β-Adrenergic agonist and has been found to be used as a growth promotant. Synonyms: (+/-)-trans-4,5,6,7-Tetrahydro-7-hydroxy-6-(isopropylamino-d7)imidazo[4,5,1-jk][1]benzazepin-2(1H)-one; RU-42173-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1217818-36-4. Molecular formula: C14H12D7N3O2. Mole weight: 268.37.
Ziprasidone-[d8]
A labelled form of Ziprasidone which is an antagonist of both 5-HT and dopamine receptor and it has been studied to show effective antipsychotic activity. Uses: A labelled form of ziprasidone which is an antagonist of both 5-ht and dopamine receptor and has been studied to show effective antipsychotic activity. Synonyms: Ziprasidone-d8; 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl-d8]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one; 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl-d8]ethyl]-6-chloro-2-indolinone; 5-[2-[4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one-d8; Geodon-d8; Zeldox-d8. Grade: 97% by CP; 97% atom D. CAS No. 1126745-58-1. Molecular formula: C21H13D8ClN4OS. Mole weight: 452.92.
Ziprasidone EP Impurity A
An impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Synonyms: 3-(1-Piperazinyl)-1,2-benzisothiazole; 3-(piperazin-1-yl)benzo[d]isothiazole; 3-Piperazin-1-yl-benzo[d]isothiazole; Ziprasidone Related Compound A. Grade: 98.0%. CAS No. 87691-87-0. Molecular formula: C11H13N3S. Mole weight: 219.31.
(+)-ZK 216348
(+)-ZK 216348 is a selective nonsteroidal glucocorticoid receptor (GR) agonist for the treatment of experimental colitis (IC50 values of 20, 20, and 80 nM for GR, Progesterone (PR) and Mineralocorticoid (MR) receptors, respectively). (+)-ZK 216348 exhibits antiinflammatory activity for both systemic and topical application, and shows no negative effects on intestinal epithelial migration or proliferation. Synonyms: ZK216348; ZK 216348; ZK-216348; 4-(2,3-dihydro-1-benzofuran-7-yl)-2-hydroxy-4-methyl-N-(4-methyl-1-oxo-2,3-benzoxazin-6-yl)-2-(trifluoromethyl)pentanamide. Grade: 99%. CAS No. 669073-68-1. Molecular formula: C24H23F3N2O5. Mole weight: 476.45.
Zoalene-[Dinitolmide-d5]
Zoalene-[Dinitolmide-d5] is the labelled analogue of Zoalene. Zoalene is a fodder additive used for prevention of coccidiosis infections. Synonyms: Zoalene-D5 (Dinitolmide-D5). Grade: 95% by HPLC; 98% atom D. CAS No. 1596379-06-4. Molecular formula: C8H2D5N3O5. Mole weight: 230.2.
Zofenoprilat-[d5]
One of the isotopic labelled impurities of Zofenopril, which is an ACE inhibitor and could be used as an antihypertensive agent. Synonyms: (4S)-1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-4-(phenyl-d5-thio)-L-proline; [1(R*),2α,4α]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-(phenyl-d5-thio)-L-proline; SQ 26333-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 1217716-12-5. Molecular formula: C15H14NO3S2D5. Mole weight: 330.48.
Zofenoprilat N-Ethyl Succinimide-[d5]
One of the isotopic labelled impurties of Zofenopril, which is an ACE inhibitor and could be used as an antihypertensive agent. Synonyms: Zofenoprilat-d5 NES Adduct; Zofenoprilat-NES-d5. CAS No. 1217546-60-5. Molecular formula: C21H21D5N2O5S2. Mole weight: 455.61.
Zofenopril-[d5]
One of the isotopic labelled form of Zofenopril, which is an ACE inhibitor and could be used as an antihypertensive agent. Synonyms: (2S,4S)-1-((S)-3-(benzoylthio)-2-methylpropanoyl)-4-(phenylthio)pyrrolidine-2-carboxylic acid-d5; [1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline-S-benzoyl-d5. Grade: >99%. Molecular formula: C22H18D5NO4S2. Mole weight: 434.58.
Zolmitriptan
Zolmitriptan is a selective serotonin receptor agonist used to treat migraine. Uses: Serotonin 5-ht1 receptor agonists. Synonyms: (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone; BW-311C90; Zomig; 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-; 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (S)-; (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]oxazolidin-2-one; (S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; 311C90; Amigrawest; Asco Top; BW 311C90; No-migraine Z; Xolnox; Zipton; Zominat. Grade: >98%. CAS No. 139264-17-8. Molecular formula: C16H21N3O2. Mole weight: 287.36.
Zolmitriptan-[d6]
Zolmitriptan-[d6] is the labelled analogue of Zolmitriptan, which is a 5HTID-receptor agonist and has been found to be effective in the treatment of migraine. Synonyms: Zolmitriptan D6. Grade: 95% by HPLC; 98% atom D. CAS No. 1217644-84-2. Molecular formula: C16H15D6N3O2. Mole weight: 293.39.
Zonisamide-[13C2,15N]
Zonisamide-[13C2,15N] is the labelled analogue of Zonisamide, which is a Sulfonamide-derived antiseizure agent and coule be used as a neuroprotective as well as neuroresearch agent. Synonyms: Zonisamide 13C2 15N; 1,2-Benzisoxazole-13C2-3-methanesulfonamide-15N; 3-(Sulfamoyl-15N-methyl)-1,2-benzisoxazole-13C2. Grade: 95% by HPLC; 98% atom 13C; 98% atom 15N. CAS No. 1188265-58-8. Molecular formula: C6[13C]2H8N[15N]O3S. Mole weight: 215.20.
Zonisamide-[13C6]
An isotope labelled Zonisamide. Zonisamide can be used to treat the symptoms of epilepsy and Parkinson's disease. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1435934-68-1. Molecular formula: C2[13C]6H8N2O3S. Mole weight: 218.18.
Zonisamide-[d4]
An isotope labelled Zonisamide. Zonisamide can be used to treat the symptoms of epilepsy and Parkinson's disease. Uses: Labelled sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive t-type calcium currents. heterocyclic methanesulfonide with anticonvulsant properties. the compound is under investigation f. Synonyms: Zonisamide D4. Grade: 95% atom D. CAS No. 1020720-04-0. Molecular formula: C8H4D4N2O3S. Mole weight: 216.25.
Z,Z-Dienestrol-[d6]
Z,Z-Dienestrol-[d6] is a labelled metabolite of Diethylstilbestrol. Uses: A labelled metabolite of diethylstilbestrol. Synonyms: 3,4-Bis(4-hydroxyphenyl)-2,4-hexadiene-d6; β-Dienestrol-d6; Z,Z-Dienestrol D6. CAS No. 91297-99-3. Molecular formula: C18H12D6O2. Mole weight: 272.37.