BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Sp-8-AEA-cAMPS-Agarose | Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. |  |
| Sp-8-AET-cGMPS | Sp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-92-3. Molecular formula: C12H17N6O6PS2. Mole weight: 436.4. | |
| Sp-8-AET-cGMPS-Agarose | Sp-8-AET-cGMPS-Agarose is the protein kinase G activator Sp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-AHA-cAMPS-Agarose | Sp-8-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-BnT-2'-O-Me-cAMPS / "S-223" | Sp-8-BnT-2'-O-Me-cAMPS is the most potent 2'-substituted activator of Epac2. In human osteosarcoma U2OS cell lines expressing Epac1 or Epac2, Sp-8-BnT-2'-O-Me-cAMPS does not induce Epac signalling at 100 μM possibly for inefficient cellular uptake in this biosystem. Synonyms: 8- Benzylthio- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O5PS2 · Na. Mole weight: 503.5. | |
| Sp-8-BnT-cAMPS / "S-220" | Sp-8-BnT-cAMPS is an exceptional stimulant targeting protein kinase A (PKA) with remarkable precision. While S-220 is an exquisite synthetic compound with antimicrobial prowess. Synonyms: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C17H17N5O5PS2 · Na. Mole weight: 489.5. | |
| Sp-8-Br-cAMPS | Sp-8-Br-cAMPS is a resistant activator of protein kinase A, the cAMP agonist. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 127634-20-2. Molecular formula: C10H10BrN5O5PS · Na. Mole weight: 446.2. | |
| Sp-8-Br-cAMPS-AM | Sp-8-Br-cAMPS-AM is a PDE-resistant precursor of Sp-8-Br-cAMPS, the protein kinase A stimulator. The active analogue is released after the metabolism of Sp-8-Br-cAMPS-AM by esterases. Synonyms: 8- Bromoadenosine- 3', 5'- monophosphorothioate, acetoxymethyl ester, Sp- isomer ( Sp-8-Br-cAMPS-AM ). Grades: ≥ 97% by HPLC for mixture of the axial and equatorial isomer. Molecular formula: C13H15BrN5O7PS. Mole weight: 496.2. | |
| Sp-8-pCPT-cGMPS | Sp-8-pCPT-cGMPS is a stimulator of protein kinase G type I α and type II with superior membrane permeability and stability. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 160385-87-5. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9. | |
| Sp-8-pCPT-PET-cGMPS | Sp-8-pCPT-PET-cGMPS is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Sp-8-Br-PET-cGMPS, Sp-8-pCPT-PET-cGMPS is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)-β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 1262749-63-2. Molecular formula: C24H18ClN5O6PS2 · Na. Mole weight: 626. | |
| Sp-8-PIP-cAMPS | Sp-8-PIP-cAMPS is a selective cAMP analogue with a preference for site B of protein kinase A type II. Synonyms: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 156816-35-2. Molecular formula: C15H20N6O5PS · Na. Mole weight: 450.4. | |
| Spacer C12 CE Phosphoramidite | Spacer phosphoramidites C3, 9, and 18 are used to insert spacer arms in oligonucleotides. When a longer spacer is required, the compound can be added multiple times. Synonyms: 3-[12-[bis (4-methoxyphenyl) -phenylmethoxy]dodecoxy-[di (propan-2-yl) amino]phosphanyl]oxypropanenitrile. Grades: >95% by HPLC. CAS No. 158665-27-1. Molecular formula: C42H61N2O5P. Mole weight: 704.93. | |
| Spacer Phosphoramidite 18 | Spacer phosphoramidites 18 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 1,1-Bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: >95% by HPLC. Molecular formula: C42H61N2O10P. Mole weight: 784.93. | |
| Spacer Phosphoramidite 9 | Spacer phosphoramidites 9 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: 9-O-Dimethoxytrityl-triethylene glycol,1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: >95% by HPLC. CAS No. 146668-73-7. Molecular formula: C36H49N2O7P. Mole weight: 652.77. | |
| Sp-c-diAMPS | Sp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger. Synonyms: Cyclic diadenosine monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O11P2S (free acid). Mole weight: 674.5 (free acid). | |
| Sp-c-diGMPS | Sp-c-diGMPS is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions. Synonyms: Cyclic diguanosine monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1259875-39-2. Molecular formula: C20H24N10O13P2S (free acid). Mole weight: 706.5 (free acid). | |
| Sp-cGMPS | Sp-cGMPS is a resistant stimulator of cGMP-dependent protein kinases. Synonyms: Guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 86562-10-9. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3. | |
| Stavudine 5'-monophosphate triethyammonium salt | Stavudine 5'-monophosphate triethyammonium salt is an invaluable biomedical compound, serving as a potent tool for studying HIV infection. By effectively impeding the virus's replication, it functions as an exemplary nucleotide reverse transcriptase inhibitor. Such inhibition is augmented by the salt form is as it heightens the stability and solubility of stavudine 5'-monophosphate. Synonyms: 2',3'-Didehydro-2'-3'-dideoxythymidine 5'-monophosphate sodium salt. | |
| Stearoyl coenzyme A | Stearoyl-CoA is a coenzyme involved in the metabolism of fatty acids. Stearoyl-CoA is a long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of stearic acid. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a long-chain fatty acyl-CoA and an 11,12-saturated fatty acyl-CoA. It derives from an octadecanoic acid. It is a conjugate acid of a stearoyl-CoA(4-). Synonyms: n-Octadecanoyl coenzyme A; stearoyl-CoA; S- [2- [3- [ [ (2R) -4- [ [ [ (2R, 3S, 4R, 5R) -5- (6-aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3, 3-dimethylbutanoyl] amino] propanoylamino] ethyl] octadecanethioate; Octadecanoyl-CoA; Octadecanoyl-coenzyme A; Stearoyl-coenzyme A. Grades: 92-98%. CAS No. 362-66-3. Molecular formula: C39H70N7O17P3S. Mole weight: 1034.00. | |
| Stearoyl coenzyme A lithium | Stearoyl coenzyme A lithium is an invaluable compound serving as a pivotal nexus in the hallowed realm of lipid synthesis. It aids in studying lipid disorders, metabolic syndrome and analogous afflictions. Synonyms: n-Octadecanoyl Coenzyme A. CAS No. 193402-48-1. Molecular formula: C39H70N7O17P3S·xLi. Mole weight: 1034.00. | |
| tC Nucleoside | tC Nucleoside, an exceptional fluorescent analogue of thymidine intended for DNA synthesis and detection, has proven to be instrumental in numerous DNA studies. Its use in DNA hybridization, polymerase chain reaction (PCR), and DNA sequencing is scientifically deemed significant. Additionally, its exclusive fluorescent properties have contributed significantly to drug discovery research as it enables accurate detection of interactions with DNA. Grades: ≥ 97%. CAS No. 162902-04-7. Molecular formula: C15H15N3O4S. Mole weight: 333.36. | |
| Tetra-N-acetyl Kanamycin A | Protected Kanamycin A. Antibiotic complex produced by Streptomyces kanamyceticus Okami & Umezawa from Japanese soil. Comprised of three components, kanamycin A, the major component, and kanamycins B and C, two minor congeners. Antibacterial. Synonyms: 4-[O-3-Acetamido-3-deoxy-α-D-glucopyranosyl-6-O-[6-acetamido-6-deoxy-α-D-glucopyranosyl]-N,N'-diacetyl-2-deoxy-D-streptamine; 6-[O-3-Acetamido-3-deoxy-α-D-glucopyranosyl-4-O-[6-acetamido-6-deoxy-α-D-glucopyranosyl]-N,N'-diacetyl-2-deoxy-D-streptamine. Grades: 98%. CAS No. 20399-23-9. Molecular formula: C26H44N4O15. Mole weight: 652.65. | |
| TFA-Hexylaminolinker Phosphoramidite | TFA-Hexylaminolinker Phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Synonyms: TFA-aminolinker C6 phosphoramidite; 2-Cyanoethyl (6-(2,2,2-trifluoroacetamido)hexyl) diisopropylphosphoramidite; 6-(N-Trifluoroacetamido)hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: ≥90%. CAS No. 133975-85-6. Molecular formula: C17H31F3N3O3P. Mole weight: 413.42. | |
| Thieno-GTP | Thieno-GTP, a potent biomolecule, has a critical role in activating G proteins, rendering it a valuable asset for biomedical research. It is extensively used in studying and comprehending biological processes related to diseases such as cancer and neurological disorders, as well as developing innovative drugs for multiple therapeutic domains. Its versatility in revealing the complex network of cellular signaling pathways through G proteins makes it a highly sought-after tool for researchers worldwide. Synonyms: Thienoguanosine-5'-Triphosphate; thGTP; 2-Aminothieno[3,4-d]pyrimidine-ribonucleoside-5'-Triphosphate. Grades: ≥95% by AX-HPLC. Molecular formula: C11H16N3O14P3S. Mole weight: 539.25. | |
| Thymidine-3',5'-di(p-nitrophenyl Phosphate) Disodium Salt | It is an artificial chromophoric substrate, could be used as a synthetic substrate for bovine pancreatic deoxyribonuclease. Uses: An artificial chromophoric substrate. Synonyms: 3'-Thymidylic Acid Mono(4-nitrophenyl) Ester 5'-(4-Nitrophenyl Hydrogen Phosphate) Disodium Salt. CAS No. 24418-12-0. Molecular formula: C22H22N4Na2O15P2. Mole weight: 688.34. | |
| Thymidine 3?-monophosphate sodium salt | Cas No. 108320-91-8. | |
| Thymidine-5'-carboxylic acid | Thymidine-5'-carboxylic acid is a remarkable biomedical compound, exhibiting immense potential in studying a plethora of ailments linked to DNA synthesis and reparative processes. Its pivotal contribution to nucleic acid metabolism renders it indispensable in the realm of molecular biology investigations, where it predominantly serves as a precursor for an array of thymidine derivatives. Synonyms: 1,2-Dideoxy-1-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-b-D-erythro-pentofuranuronic acid. Grades: 95%. CAS No. 3544-99-8. Molecular formula: C10H12N2O6. Mole weight: 256.21. | |
| Thymidine-5'-diphosphate-D-glucose disodium salt | Thymidine-5'-diphosphate-D-glucose disodium salt is a pivotal chemical compound, manifesting itself as an indispensable substrate for enzymes participating in glycogen synthesis. Consequently, it exerts remarkable applications in the research of glycogen storage diseases. Synonyms: 2'-Deoxy-thymidine-5'-diphospho-a-D-glucose disodium salt; TDP-Glucose disodium salt; disodium,[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-oxidophosphoryl][(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate; Thymidine-5 inverted exclamation marka-diphospho-alpha-D-glucose disodium salt; dTDP-alpha-glc-Na2; TDP-alpha-Glucose; TDP-alpha-Glc; TDP-alpha-G. CAS No. 148296-43-9. Molecular formula: C16H24N2O16P2Na2. Mole weight: 608.29. | |
| Thymidine-5'-diphosphate-D-viosamine disodium salt | Thymidine-5'-diphosphate-D-viosamine disodium salt is an indispensable constituent within the biomedical realm assuming a pivotal application in studying nucleotide metabolism while concurrently serving as an enzymatic reaction substrate, thereby illuminating the enigmatic intricacies entailed by biochemical pathways. Grades: ≥ 95% (HPLC). CAS No. 244226-72-0. Molecular formula: C16H25N3O14P2Na2. Mole weight: 591.31. | |
| Thymidine 5'-Diphosphate Sodium Salt | Thymidine 5'-Diphosphate Sodium Salt is a nucleoside diphosphate derived from phosphorylation of Thymidine. Which is produced from Thymidine monophosphate by Thymidylate kinase (TMPK), that is a nucleoside monophosphate kinase and can be futher phosphorylated to its active triphosphate antiviral or antitumor moieties. A proximate precursor for DNA synthesis. Synonyms: Thymidine 5'-(Trihydrogen Diphosphate) Sodium Salt. Grades: 90%. CAS No. 108322-12-9. Molecular formula: C10H16N2O11P2 xNa. Mole weight: 402.19. | |
| Thymidine-5'-monophosphate | Thymidine-5'-monophosphate, a nucleotide intermediate, serves as a research tool for gaining insights into intricate cellular processes and pathways engaged in DNA synthesis and repair. Studies utilizing Thymidine-5'-monophosphate extend to chemotherapy and antiviral drug development for possible therapeutic intervention. Its diverse extracellular functions can aid disease control. Synonyms: 5'-Thymidylic acid; dTMP; Thymidylic acid; Thymidine monophosphate; 5-Methyl-dUMP; Thymidine-5'-monophosphoric acid; Deoxy TMP; Thymidine 5'-(dihydrogen phosphate); NSC 46713; 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate). Grades: ≥98% by HPLC. CAS No. 365-07-1. Molecular formula: C10H15N2O8P. Mole weight: 322.21. | |
| Thymidine 5-triphosphate | Cas No. 365-08-2. | |
| Thymidine 5'-Triphosphate Sodium Salt | It is a metabolite of Thymidine. As well as a Thymidine analogue as phosphate donor. Synonyms: Thymidine 5'-(tetrahydrogen triphosphate) sodium salt; Deoxythymidine triphosphate sodium salt; Thymidine 5'-(tetrahydrogen triphosphate), sodium salt (1:x); TTP sodium salt. Grades: 95%. CAS No. 18423-43-3. Molecular formula: C10H17N2O14P3.xNa. Mole weight: 482.17 (free acid). | |
| Thymidine glycol CEP | Thymidine glycol CEP is an indispensable biomolecular compound, exhibiting immense application for involvement within the intricate fabric of drug formulation centered around maladies originating from DNA impairment. This compound stands out as a prominent tool for specifically researching the targeting DNA damage-related disorders. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-(5R,6S)-5,6-bis(t-butyldimethylsilyloxy)-5,6-dihydroThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 318497-58-4. Molecular formula: C52H79N4O10PSi2. Mole weight: 1007.36. | |
| Thymidine (riboside) | Thymidine (riboside) holds a crucial place in cancer therapy due its nucleoside role within DNA and function as a radiosensitizer. Moreover, it serves as a DNA precursor whilst it has potential to treat mitochondrial disorders and can be paired with other drugs in cancer treatment procedures. Hence, Thymidine (riboside) is a multipurpose drug in the field of medical science that calls for further research and investigation. Grades: ≥ 98% by HPLC. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt | Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is an indispensible compound, assuming a pivotal function in the research of assorted ailments linked to hindered DNA synthesis, including specific cancer variations and hereditary anomalies. Its mechanism of action involves expediting DNA synthesis and fostering cellular restoration. Synonyms: D-Thymidylyl-(3'-5')-2'-deoxy-adenosine ammonium salt; [5-(6-Aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl [2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] hydrogen phosphate azane. CAS No. 61845-39-4. Molecular formula: C20H26N7O10P·NH3. Mole weight: 572.47. | |
| TNP-ADP | TNP-ADP, the fluorescent analogue of nucleotide ADP, is frequently utilized in biomedical studies of protein conformational changes and transduction pathways activated by ADP. Its broad utility has been exemplified in the study of ADP binding interactions with proteins such as enzymes and kinases, and more importantly, probing the role of ADP in pathogenic contexts such as cardiovascular disease and various cancerous states. Synonyms: 2',3'-O-Trinitrophenyl-adenosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 77450-67-0. Molecular formula: C16H15N8O16P2. Mole weight: 637.28. | |
| TNP-AMP | TNP-AMP is a potent fluorescent probe widely employed to study adenosine receptors, which play crucial roles in various diseases, including cancer, inflammation and neurodegenerative disorders. TNP-AMP allows for visualization and quantification of adenosine receptor expression aiding in the development of novel therapies for these conditions. Synonyms: 2',3'-O-Trinitrophenyl-adenosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H14N8O13P. Mole weight: 557.3. | |
| TNP-ATP | TNP-ATP, a formidable and discerning P2X receptor antagonist, is often exploited in biomedical research to unravel the multifaceted connections P2X receptors have in a myriad of ailments, including neuropathic pain, cancer, and inflammatory disorders. Its efficacy is wrought by dissuading ATP, a cardinal neurotransmitter radiantly integrated in cell-signaling pathways. This compound is indispensable in illuminating ATP signaling's intricacies and may prove instrumental in resolving a gamut of illnesses. Synonyms: 2',3'-O-Trinitrophenyl-adenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 120360-48-7. Molecular formula: C16H16N8O19P3. Mole weight: 717.26. | |
| TNP-ATP triethylammonium salt | TNP-ATP triethylammonium salt is a high affinity and selective P2X receptor antagonist with 1000-fold selectivity over P2X2, P2X4 and P2X7. It inhibits ATP-induced currents in cells expressing P2X1, P2X3 and heteromeric P2X2/3 receptors (IC50 = 6, 0.9 and 7 nM, respectively). Synonyms: TNP-ATP; TNPATP; TNP ATP; TNP-ATP triethylammonium salt. 2',3'-O-(2,4,6-Trinitrophenyl)adenosine-5'-triphosphate tetra(triethylammonium) salt. Grades: ≥95% by HPLC. CAS No. 61368-63-6. Molecular formula: C16H13N8O19P3.C24H64N4. Mole weight: 1123.04. | |
| TNP-CTP | TNP-CTP, a small molecule compound widely utilized in the biomedical domain, boasts of its exceptional capacity to stabilize RNA. Its intricate and nuanced ability to enhance protein expression has garnered significant attention in the scientific community, particularly in terms of its potential in treating debilitating diseases such as cystic fibrosis and muscular dystrophy. Impressively, TNP-CTP has also been found to augment the efficacy of specific drugs- a trait that has sparked enthusiasm amongst researchers in the field of drug discovery and development. Synonyms: 2',3'-O-Trinitrophenyl-cytidine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C15H16N6O20P3. Mole weight: 693.24. | |
| TNP-GDP | TNP-GDP is a trinitrophenol (TNP) substituted nucleotide analog. Synonyms: 2',3'-O-Trinitrophenyl-guanosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H15N8O17P2. Mole weight: 653.28. | |
| TNP-GppNHp | TNP-GppNHp is an exceedingly sturdy GTP analogue, serving as a catalyst in instigating the activation of GTP-binding proteins, thereby affording an opportunity to scrutinize their intricate signaling cascades. Synonyms: (TNP-GMPPNP); 2',3'-O-Trinitrophenyl-guanosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C16H17N9O19P3. Mole weight: 732.28. | |
| TNP-GTP | TNP-GTP, an analog of GTP, is a fluorescent ribose-modified ATP. TNP-GTP mimic the binding characteristics of GTP, in their interactions with various enzymes and proteins. it's spectroscopic properties make it valuable tools with which to determine the kinetic parameters of nucleotide-protein interactions. Furthermore, it acts as potentially valuable fluorescence acceptors in FRET experiments. Synonyms: 2',3'-O-Trinitrophenyl-guanosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 612837-26-0. Molecular formula: C16H16N8O20P3. Mole weight: 733.26. | |
| TNP-UTP | TNP-UTP is a vital tool in biomedical research used to study RNA synthesis and modification. It is a fluorescent derivative of uridine triphosphate (UTP) and can be incorporated into RNA during transcription. TNP-UTP helps in the investigation of RNA processing and RNA-protein interactions. It aids in understanding diseases like cancer and neurodegenerative disorders at the molecular level. Synonyms: 2',3'-O-Trinitrophenyl-uridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C15H15N5O21P3. Mole weight: 694.22. | |
| TP2(Nic) | TP2(Nic): TP2(Nic) is a potent small-molecule antagonist that targets nicotinic acetylcholine receptors. with specific binding affinity, TP2(Nic) effectively inhibits the interaction between nicotine and these receptors, thereby used for studying nicotine addiction and related disorders. Synonyms: Nicotinamide thymine dinucleotide, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C21H28N4O15P2(free acid). Mole weight: 638.41 (free acid). | |
| Tricirbine | Triciribine is a potent AKT inhibitor and a cell-permeable tricyclic nucleoside molecule with potential antineoplastic activity. Akt-1, -2, and -3 are serine/threonine protein kinases in the phosphatidylinositol (PI3)-kinase signalling pathway that play a critical role in the regulation of cell proliferation and survival. Following recruitment of Akt to the plasma membrane, phosphorylation at threonine 308 and serine 473 (Akt-1 numbering) by phosphoinositide-dependent kinases (PDK) 1 and 2 results in full activation of the enzyme. Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit phosphatidylinositol 3 (PI3)-Kinase or PDK1, the direct upstream activators of Akt, nor does it inhibit PKC, PKA, ERK1/2, serum- and glucocorticoid-inducible kinase, p38, STAT3, or JNK signalling pathways. Triciribine effectively inhibits growth of Akt-overexpressing human cancer cell lines in vitro with 50% inhibition at ~5-10 μM. It also inhibit growth of tumor xenografts in mice by greater than 80% at a dose of 1 mg/kg/day. Synonyms: VQD-002; VQD 002; VQD002; NSC-154020; NSC 154020; NSC154020; Triciribine; TCN-P; triciribine; Tricyclic nucleoside; Pentaazacentopthylene; API-2; Akt Inhibitor V. Grades: 99.81%. CAS No. 35943-35-2. Molecular formula: C13H16N6O4. Mole weight: 320.309. | |
| Tricirbine Phosphate | Tricirbine Phosphate is the phosphate salt of Tricirbine. Triciribine is a tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt - Akt-1, Akt-2 and Akt-3. Triciribine is currently under studies of breast cancer and ovarian cancer as an antineoplastic. Synonyms: TCN-P; UNII-5L5GE3DV88; NSC-280594; C13H17N6O7P. CAS No. 61966-08-3. Molecular formula: C13H17N6O7P. Mole weight: 400.29. | |
| Trifluridine | Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase. TFT also inhibits thymidylate synthase (TS), a rate-limiting enzyme of DNA biosynthesis, and is incorporated into DNA. Synonyms: 5-Trifluoromethyl-2'-deoxyuridine; Trifluorothymidine; FTD; 5-Trifluorothymidine; NSC 529182; NSC 75520; Viroptic; α,α,α-Trifluorothymidine; 2'-Deoxy-5-(trifluoromethyl)uridine; Trifluoromethyldeoxyuridine; Trifluridina; Virophta; TFDU. Grades: ≥95%. CAS No. 70-00-8. Molecular formula: C10H11F3N2O5. Mole weight: 296.20. | |
| UDP-2-acetamido-2-deoxy-5-thio-D-glucopyranose | | |
| UDP-a-D-galactose ammonium salt | UDP-a-D-galactose ammonium salt is a crucial biochemical compound widely used industry. It serves as a key precursor in various biosynthetic pathways, especially in the synthesis of glycoconjugates and glycoproteins. This product plays an essential role in studying certain diseases associated with abnormal galactosylation, such as congenital disorders of glycosylation. Synonyms: UDP-D-galactose ammonium salt; UDP-α-D-Gal ammonium salt; Uridine 5'-(trihydrogen diphosphate)? P'-α-D-galactopyranosyl ester ammonium salt; UDP-galactose ammonium salt. Molecular formula: C15H30N4O17P2. Mole weight: 600.36. | |
| UDP-a-D-galacturonic acid | UDP-a-D-galacturonic acid is a crucial molecule in the biomedical industry that serves as a substrate for enzymes involved in the biosynthesis of glycosaminoglycans. It plays an essential role in the treatment of diseases related to glycosaminoglycan deficiencies, such as Maroteaux-Lamy syndrome and Sly syndrome. This product enables researchers to study the biosynthesis and metabolism of glycosaminoglycans, aiding in the development of potential therapies. Synonyms: α-D-Glucopyranuronic acid, 1?P'-ester with uridine 5'-(trihydrogen diphosphate); Uridine[5]diphospho-a-D-galacturonopyranoside; UDP-GlcUA; Glucopyranuronic acid, 1-ester with uridine 5'-pyrophosphate; α-D-Glucopyranuronic acid, ester with uridine 5'-pyrophosphate; UDP-D-glucuronic acid; UDP-glucuronic acid; UDP-α-D-glucuronic acid; Uridine 5'-diphospho-α-D-glucuronic acid; Uridine 5'-diphosphoglucuronic acid; Uridine diphosphate glucuronic acid; Uridine diphospho-D-glucuronic acid; Uridine diphosphoglucuronic acid; Uridine pyrophosphoglucuronic acid; UDP-g acid. Grades: ≥95%. CAS No. 2616-64-0. Molecular formula: C15H22N2O18P2. Mole weight: 580.29. | |
| UDPβS | UDPβS is a robust nucleotide analog, represents an essential tool, is acclaimed for its profound comprehension of diverse cellular mechanisms. It serves as an exemplary substrate, facilitating meticulous examination of carbohydrate metabolic enzymes, while also bestowing the ability to either activate or impede distinct proteins. Furthermore, UDPβS assumes a pivotal role in probing drug metabolism, deciphering intricate processes of signal transduction, as well as exploring revolutionary therapeutic modalities for afflictions like cancer and neurological disorders. Synonyms: Uridine-5'-(β-thio)-diphosphate, Sodium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C9H14N2O11P2S (free acid). Mole weight: 420.22 (free acid). | |
| UDP-Gel / UDP-Agarose | UDP-Gel is the UDP coupled to a polymeric gel by the terminal phosphate, which is used in the affinity purification of galactosyltransferases. Synonyms: Uridine- 5'- O- diphosphate, immobilized on a polymeric matrix. | |
| UDP - lyophilized | UDP-lyophilized, a pharmaceutical-grade, freeze-dried powder, is a vital metabolic nucleotide which supports the body's internal processes. It is specifically employed in diagnosing and treating inherited metabolic illnesses, like galactosemia. Additionally, UDP-lyophilized is a sought-after resource in the development of pioneering medication and biologics, mostly concerning neurological disorders - a medical frontier requiring continuous exploration. Synonyms: Uridine-5'-diphosphate, Sodium salt. Grades: ≥ 96 % by HPLC. Molecular formula: C9H14N2O12P2(free acid). Mole weight: 404.16 (free acid). | |
| UP2(Nic) | UP2(Nic), a versatile small molecule inhibitor renowned for its efficacy in blocking nicotinic acetylcholine receptors, is highly sought after in biomedical research circles for its potential medical applications. Studied extensively for its therapeutic scope, this inhibitor shows promise in the treatment of nicotine addiction and a spectrum of neurological disorders, including but not limited to Alzheimer's disease and schizophrenia. Synonyms: Nicotinamide uracil dinucleotide, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C20H26N4O16P2(free acid). Mole weight: 640.39 (free acid). | |
| Up2U / UppU | Up2U is a pioneering biomedical compound meticulously designed to study an extensive array of pernicious viral and bacterial maladies. UppU is a wide-ranging antiviral and antibiotic compound. Synonyms: P1, P2- Di- (uridine- 5')- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 26184-65-6. Molecular formula: C18H24N4O17P2 (free acid). Mole weight: 630.4 (free acid). | |
| Up4U | Up4U is a novel biomedicine designed to provide targeted treatment for various types of cancer. Utilizing advanced molecular technology, Up4U specifically targets cancer cells while minimizing damage to healthy tissues. Synonyms: P1, P4- Di- (uridine- 5')- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 59985-21-6. Molecular formula: C18H26N4O23P4 (free acid). Mole weight: 790.3 (free acid). | |
| UpG | UpG, a synthetic compound, is a crucial nucleic acid used in biosciences for developing phage-resistant bacterial strains, RNA research and studying ribosome function. Its versatility extends to testing drugs' efficacy on viral diseases including HIV and hepatitis C. Experience UpG's unparalleled attributes as a surefire benchmark in scientific experimentation. Synonyms: RNA Dinucleotide (5'?3'), Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C19H24N7O13P (free acid). Mole weight: 589.41 (free acid). | |
| UpNHpp | UpNHpp is a cutting-edge biomedical compound engineered to study the intricate realm of neurological disorders such as Alzheimer's and Parkinson's disease. Synonyms: (UMPNPP); Uridine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C9H16N3O14P3(free acid). Mole weight: 483.15 (free acid). | |
| UppNHp | UppNHp, an innovative drug delivery system widely implemented in the biomedicine field, boasts high efficacy in treating an array of ailments. Its cutting-edge architecture ensures targeted drug delivery, ameliorating harmful side effects to optimize therapeutic outcomes. This exceptional solution demonstrates extraordinary potential in curing illnesses ranging from cancer to infectious diseases, even extending to degenerative neurological conditions such as Alzheimer's and Parkinson's disease. Synonyms: (UMPPNP); Uridine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 82145-58-2. Molecular formula: C9H16N3O14P3(free acid). Mole weight: 483.15 (free acid). | |
| Uridine, 3'-?deoxy-?2'-?O-? (2-?methoxyethyl) ?-?3'-?[[ (4-?methoxyphenyl) ?diphenylmethyl]?amino]?- | Uridine, 3'-deoxy-2'-O- (2-methoxyethyl) ?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?, is a multi-faceted therapeutic candidate that exhibits anti-viral properties against various diseases such as hepatitis B, HIV, and herpes simplex virus. Moreover, uridine has drawn considerable attention in neuroscience research due to its reported potential as a treatment option for Parkinson's disease and depression, among other neurological disorders. Uridine's ability to improve phospholipid metabolism within neuronal membranes and to stimulate synaptic growth and neurite outgrowth have demonstrated its potential as a promising therapeutic agent for certain neurological conditions. Synonyms: 3'-Deoxy-2'-O- (2-methoxyethyl) -3'-[[ (4-methoxyphenyl) diphenylmethyl]amino]uridine. CAS No. 2299277-76-0. Molecular formula: C32H35N3O7. Mole weight: 573.64. | |
| Uridine 5?-Monophosphomorpholidate 4-Morpholine-N,N?-dicyclohexylcarboxamidine Salt | Cas No. 24558-91-6. | |
| Uridine-5-(N-Fmoc-methylamino)-acetyl-(9-fluorenylmethyl)ester | Uridine-5-(N-Fmoc-methylamino)-acetyl-(9-fluorenylmethyl)ester is an extensively employed compound within the biomedical fieldboasting multifaceted applications for the research of diverse ailments such as cancer, alzheimer's disease and viral infection. Grades: ≥95%. Molecular formula: C41H37N3O10. Mole weight: 731.75. | |
| Uridine-5-oxo-acetyl-(9-fluorenylmethyl)ester | Uridine-5-oxo-acetyl-(9-fluorenylmethyl)ester is an extraordinary biomedical compound widely acknowledged for its astounding capabilities in studying neurological disorders and cognitive impairments. Grades: ≥95%. Molecular formula: C25H24N2O9. Mole weight: 496.47. | |
| Uridine-5'-(tetrahydrogen triphosphate) sodium salt (1:4) | Uridine-5'-(tetrahydrogen triphosphate) sodium salt (1:4), a pivotal compound extensively utilized in the biomedical sector, serves as a fundamental substrate facilitating RNA synthesis and orchestrating intricate cellular metabolism. Its profound importance becomes pronounced in the realm of managing neurological maladies, such as Parkinson's disease, where it bolsters neurotransmitter activity. Synonyms: Uridine 5'-triphosphate tetrasodium; Uridine 5'-(tetrahydrogen triphosphate), tetrasodium salt; Uridine 5'-triphosphate sodium salt;Uridine STP; URIDINE TRIPHOSPHATE SODIUM [WHO-DD];[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate. CAS No. 14264-46-1. Molecular formula: C9H15N2O15P3·4Na. Mole weight: 576.10. | |
| Uridine 5'-(trihydrogendiphosphate), P'-b-D-glucopyranosylester, sodium salt (9CI) | Uridine 5'-(trihydrogendiphosphate), P'-b-D-glucopyranosylester, sodium salt (9CI) is a biomedical compound applied in the realm of nucleotide metabolism, assuming a pivotal role by proficiently facilitating the synthesis of RNA and DNA. Synonyms: UDP-ALPHA-D-GLUCOSE, DISODIUM SALT; UDPG; UDPG 2NA; UDPG DISODIUM SALT; UDP-GLC, 2NA; UDP-GLC, DISODIUM SALT. Grades: ≥98%. CAS No. 117756-22-6. Molecular formula: C15H24 N2 O17 P2. x Na. Mole weight: 610.27. | |
| Uridine 5-triphosphate | Uridine 5-triphosphate, a vital RNA building block produced endogenously in human cells, plays a significant role in cell metabolism. Its indispensable value in the biomedical industry for DNA sequencing, gene expression analysis, and likely therapeutic applications cannot be overemphasized. The extensive possibilities of applying this nucleotide in the treatment of cardiovascular diseases, neurological disorders, and select types of cancer is worth being explored. Synonyms: UTP; Uridine 5'-(tetrahydrogen triphosphate); uridine triphosphate; Uteplex. Grades: ≥95% by HPLC. CAS No. 63-39-8. Molecular formula: C9H15N2O15P3. Mole weight: 484.14. | |
| Uridine Diphosphate Choline (UDPC) | Uridine Diphosphate Choline (UDPC) is a fundamental biochemical compound inherent to the human body assuming indispensability in an array of intricate cellular processes. It has biomedical application for studying neurodegenerative afflictions such as Alzheimer's disease, Parkinson's disease and cognitive impairments. Notably, UDPC functions as a precursor, stimulating the production of acetylcholine. Synonyms: Uridine 5'-(Trihydrogen Diphosphate) P'-[2-(TriMethylaMMonio)ethyl] Ester Inner Salt. Grades: > 95%. CAS No. 99492-83-8. Molecular formula: C14H25N3O12P2. Mole weight: 489.32. | |
| Uridylyl-2'-5'-uridine ammonium salt | Uridylyl-2'-5'-uridine ammonium salt is an indispensable and pivotal biomolecule within the biomedical sector, involved in the intricate orchestration of RNA sequence synthesis and modification. Its indispensable functionality encompasses the research of cellular wholeness and the orchestration of gene expression. Synonyms: D-Uridylyl-2'-5'-uridine ammonium salt. Grades: 95%. CAS No. 108321-54-6. Molecular formula: C18H23N4O14P·NH3. Mole weight: 567.41. | |
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