BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tildipirosin-[d10] | A labelled analogue of Tildipirosin. Tildipirosinb is a novel 16-membered-ring macrolide used in veterinary medicine. Tildipirosin is used to treat bacterial pathogens including Mannheimia haemolytica and Pasteurella multocida that cause respiratory tract infections in cattle and swine. Synonyms: 20-Deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranosyl]-20,23-di-1-piperidinyltylonolide-d10. Grade: >98%. Molecular formula: C41H61D10N3O8. Mole weight: 744.08. |  |
| Tinidazole | Tinidazole kills the metronidazole-susceptible isolates at a low MLC but is effective against only 4 of the 12 metronidazole-resistant isolates. Synonyms: Tinidazole; Bioshik; CP 12,574; CP 12574; CP-12,574; CP-12574; CP12,574; CP12574; Farmasierra; Fasigin; Fasigyn; Fasigyne; Fasygin; Simplotan; Teofarma; Tinidazole; Tricolam. Grade: >98%. CAS No. 19387-91-8. Molecular formula: C8H13N3O4S. Mole weight: 247.27. | |
| Tiopronin | Tiopronin is a US Food and Drug Administration (FDA)-approved drug for the treatment of cystinuria by controlling the rate of cystine precipitation and excretion. Synonyms: N-(2-Mercapto-1-oxopropyl)glycine; N-(2-Mercaptopropionyl)glycine; Acadione; Thiolpropionamidoacetic Acid. Grade: >98%. CAS No. 1953-2-2. Molecular formula: C5H9NO3S. Mole weight: 163.19. | |
| Tiopronin-[d3] | Tiopronin-[d3] is the labelled analogue of Tiopronin, which could be used as an antidote in poisoning caused by heavy metals. Synonyms: Tiopronin D3; N-(2-Mercapto-1-oxopropyl)glycine-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1189700-74-0. Molecular formula: C5H6D3NO3S. Mole weight: 166.21. | |
| Tiotropium bromide | Tiotropium Bromide, an azoniatricyclo derivative, is a mAChR antagonist that could be used as bronchodilation agent and smooth muscle relaxant. Uses: Tiotropium bromide is a machr antagonist that could be used as bronchodilation agent and smooth muscle relaxant. Synonyms: PUR-0200; PUR0200; PUR 0200; BA 679BR; BA-679BR; BA679BR; TIOTROPIUM BROMIDE; Spiriva; Spiriva Respimat; Spiriva Handihaler; Tiotropium (Bromide). Grade: >99%. CAS No. 136310-93-5. Molecular formula: C19H22BrNO4S2. Mole weight: 472.41. | |
| Tiotropium-[d3] Bromide | Tiotropium-[d3] Bromide is the labelled analogue of Tiotropium bromide. Tiotropium bromide is an anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Synonyms: Tiotropium D3 Bromide; (1α,2β,4β,5α,7β)-7-[(2-Hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-d3 Bromide. Grade: 98% by HPLC; 99% atom D. CAS No. 1127226-56-5. Molecular formula: C19H19D3BrNO4S2. Mole weight: 475.43. | |
| Tiotropium-[d3] Iodide | An isotope labelled derivative of Tiotropium bromide. Tiotropium bromide is an anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Synonyms: (1R,2R,4S,5S,7S)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9-(D3)methyl-9-methyl-3-oxa-9-azatricyclo[3.3.1.0,4]nonan-9-ium iodide. Grade: 95% by HPLC; 98% atom D. CAS No. 412010-61-8. Molecular formula: C19H19D3NO4S2I. Mole weight: 522.44. | |
| Tipelukast-[d6] | Tipelukast-[d6] is the labelled analogue of Tipelukast, which could be used as an oral anti-inflammatory agent and has been found to exhibit potential activities against non-alcoholic fatty liver disease as a leukotriene receptor antagonist. Synonyms: Tipelukast-D6. Molecular formula: C29H32D6O7S. Mole weight: 536.71. | |
| Tipranavir-[d4] | Tipranavir-[d4] is the labelled analogue of Tipranavir, which is a nonpeptidic HIV protease inhibitor and has been found to be effective as an antiviral. Synonyms: Tipranavir D4; N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1217819-15-2. Molecular formula: C31H29D4F3N2O5S. Mole weight: 606.69. | |
| Tizanidine-[d4] | Tizanidine-[d4] is the labelled analogue of Tizanidine. Tizanidine is an α2 adrenergic agonist used as a muscle relaxant. Synonyms: Tizanidine D4; 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl-d4)-2,1,3-benzothiadiazol-4-amine. Grade: 100% HPLC; 99% atom D. CAS No. 1188331-19-2. Molecular formula: C9H4DClN5S. Mole weight: 257.74. | |
| Tizanidine-[d4] Hydrochloride | Tizanidine-[d4] Hydrochloride is the labelled analogue of Tizanidine, which has been found to be an α2-adrenergic agonist and could be used as a muscle as well as skeletal relaxant. Synonyms: Tizanidine-d4 Hydrochloride; 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl-d4)-2,1,3-benzothiadiazol-4-amine Hydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1188263-51-5. Molecular formula: C9H5D4Cl2N5S. Mole weight: 294.20. | |
| Tizoxanide-[d4] | Tizoxanide-[d4] is the labelled analogue of Tizoxanide. Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. Synonyms: Tizoxanide D4; 2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1246817-56-0. Molecular formula: C10H3D4N3O4S. Mole weight: 269.27. | |
| (-)-TK216 | (-)-TK216 is an enantiomer of TK216, which is a potent and orally active inhibitor of E26 transformation specific (ETS). (-)-TK216 has anti-cancer activity. Synonyms: 2H-Indol-2-one, 4,7-dichloro-3-[2-(4-cyclopropylphenyl)-2-oxoethyl]-1,3-dihydro-3-hydroxy-, (-)-. Grade: ≥95%. CAS No. 1903783-78-7. Molecular formula: C19H15Cl2NO3. Mole weight: 376.23. | |
| (+)-TK216 | (+)-TK216 is an enantiomer of TK216, which is a potent and orally active inhibitor of E26 transformation specific (ETS). Synonyms: 2H-Indol-2-one, 4,7-dichloro-3-[2-(4-cyclopropylphenyl)-2-oxoethyl]-1,3-dihydro-3-hydroxy-, (+)-. Grade: ≥95%. CAS No. 1903783-77-6. Molecular formula: C19H15Cl2NO3. Mole weight: 376.23. | |
| Tofacitinib-[13C3] | Tofacitinib-[13C3] is a pyrrolo[2,3-d]pyrimidine derivative, as a Janus kinase inhibitor for treatment of rheumatoid arthritis. Synonyms: 1-(Cyanoacetyl-13C3)-4R-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3R-piperidinamine. Grade: ≥90%. Molecular formula: C13[13C]3H20N6O. Mole weight: 315.35. | |
| Tofacitinib citrate | Tofacitinib (trade name Xeljanz, formerly tasocitinib, CP-690550) is a drug discovered and developed by Pfizer. It is currently approved for the treatment of rheumatoid arthritis (RA) in the United States and is being studied for treatment of psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. (source: http://en.wikipedia.org/wiki/Tofacitinib). Uses: Janus kinase inhibitors. Synonyms: CP-690550; CP 690550; CP690550; Tofacitinib; tasocitinib. Grade: 98%. CAS No. 540737-29-9. Molecular formula: C22H28N6O8. Mole weight: 504.5. | |
| Tofacitinib-[d3] | One of the isotopic labelled form of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile-d3. Molecular formula: C16H17D3N6O. Mole weight: 315.39. | |
| Tolazoline hydrochloride | Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. Grade: >98%. CAS No. 59-97-2. Molecular formula: C10H12N2.HCl. Mole weight: 196.68. | |
| Tolbutamide-[d9] | Tolbutamide-[d9] is the labelled analogue of Tolbutamide. Tolbutamide is an inhibitor of potassium channel, used for type II diabetes. Synonyms: Tolbutamide D9; 4-Methyl-N-{[2-(2H3)methyl(2H6)propan-2-yl]carbamoyl}benzene-1-sulfonamide. Grade: 95% by HPLC; 98% atom D. CAS No. 1219794-57-6. Molecular formula: C12H9D9N2O3S. Mole weight: 279.40. | |
| Tolcapone-[d4] | Tolcapone-[d4] is the labelled analogue of Tolcapone. Tolcapone is a nitrocatechol-type inhibitor of the enzyme catechol-O-methyltransferase. It can be used to treat Parkinson's disease. Synonyms: Tolcapone D4; (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl-d4)methanone. Grade: 95% by HPLC; 98% atom D. CAS No. 1246816-93-2. Molecular formula: C14H7D4NO5. Mole weight: 277.27. | |
| Tolcapone-[d7] | An isotope labelled form of Tolcapone. Tolcapone is a nitrocatechol-type inhibitor of the enzyme catechol-O-methyltransferase. It can be used to treat Parkinson's disease. Synonyms: Tolcapone-d7; 5-[4-(D3)methyl(D4)benzoyl]-3-nitrobenzene-1,2-diol. Grade: 95% by HPLC; 98% atom D. CAS No. 2749285-04-7. Molecular formula: C14H4D7NO5. Mole weight: 280.28. | |
| Tolfenamic acid-[13C6] | Tolfenamic acid-[13C6] is the labelled analogue of Tolfenamic acid, which is a non-steroidal anti-inflammatory drug (NSAID). It is a derivative of anthranilic acid, related structurally to Mefenamic and Flufenamic acids. Synonyms: 2-(3-Chloro-2-methyl-phenylamino)-13C6-benzoic acid; Tolfenamic acid-13C6; Tolfenamic Acid-(Benzoic ring-13C6); N-(3-Chloro-o-tolyl)anthranilic Acid-13C6; Clotam-13C6; Migea-13C6; N-(2-Methyl-3-chlorophenyl)anthranilic Acid-13C6; Tolfedine-13C6; Tolfine-13C6. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1420043-61-3. Molecular formula: C8[13C]6H12ClNO2. Mole weight: 267.66. | |
| Tolfenamic Acid-[d4] | Tolfenamic Acid-[d4] is the labelled analogue of Tolfenamic Acid, which is a non-steroidal anti-inflammatory drug (NSAID). It is a derivative of anthranilic acid, related structurally to Mefenamic and Flufenamic acids. Synonyms: Tolfenamic Acid D4; 2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid-d4; N-(3-Chloro-o-tolyl)anthranilic Acid-d4; Clotam-d4; Migea-d4; N-(2-Methyl-3-chlorophenyl)anthranilic Acid-d4; Tolfedine-d4; Tolfine-d4. Grade: 98% by HPLC; 99% atom D. CAS No. 1246820-82-5. Molecular formula: C14H3D4ClNO2. Mole weight: 265.73. | |
| Tolnaftate-[d7] | Tolnaftate-[d7] is the labelled analogue of Tolnaftate, which could be used as an Antifungal agent. Synonyms: Tolnaftate D7; N-Methyl-N-(3-methylphenyl)carbamothioic Acid O-2-Naphthalenyl-d7 Ester. Grade: 95% by HPLC; 95% atom D. CAS No. 1329835-64-4. Molecular formula: C19H10D7NOS. Mole weight: 314.45. | |
| Tolperisone-[d10] Hydrochloride | Tolperisone-[d10] Hydrochloride is the labelled analogue of Tolperisone, which is an ion channel blocker and centrally-acting muscle relaxant. Synonyms: Tolperisone D10 Hydrochloride; 2-Methyl-1-(4-methylphenyl)-3-(1-piperidinyl-d10)-1-propanone Hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1185160-65-9. Molecular formula: C16H13D10NOHCl. Mole weight: 291.88. | |
| (±)-Tolterodine-d14 Tartrate [N,N-di(iso-propyl-d7)] | One of the isotopic labelled form of (±)-Tolterodine, which is an antimuscarinic agent and could be used against urinary incontinence. Synonyms: (±)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl-3-phenylpropylamine) tartrate. Grade: 95% by HPLC; 98% atom D. CAS No. 1191280-43-9. Molecular formula: C26H23D14NO7. Mole weight: 489.67. | |
| Toltrazuril-[d3] | Toltrazuril-[d3] is the labelled analogue of Toltrazuril. Toltrazuril has been found to be an antiprotazoal agent and could be used against Equine Protozoal Myeloencephalitis. Synonyms: Toltrazuril D3; 1-Methyl-3-[3-methyl-4-[4-[(trifluoromethyl)thio]phenoxy]phenyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1353867-75-0. Molecular formula: C18H11D3F3N3O4S. Mole weight: 428.4. | |
| Toltrazuril sulfone-[d3] | Toltrazuril sulfone-[d3] is a labelled impurity of Toltrazuril. Toltrazuril has been found to be an antiprotazoal agent and could be used against Equine Protozoal Myeloencephalitis. Synonyms: Ponazuril-d3; Toltrazuril-d3 Sulfone; Toltrazuril sulfone (N-methyl-d3); 1-Methyl-D3-3-[3-methyl-4-(4-trifluoromethanesulfonylphenoxy)-phenyl]-[1,3,5]triazinane-2,4,6-trione. Grade: 95% by HPLC; 98% atom D. CAS No. 1346602-48-9. Molecular formula: C18H11D3F3N3O6S. Mole weight: 460.4. | |
| Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester | Posaconazole Diastereoisomer Related Compound 8 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: Posaconazole intermediate. antifungal agent. Synonyms: Posaconazole Impurity 29; (5R-cis)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester; p-Toluenesulfonic Acid (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl Ester; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; Posaconazole Impurity. Grade: >95%. CAS No. 149809-43-8. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Tolvaptan-[d7] | Tolvaptan-[d7] is the labelled analogue of Tolvaptan, which has been found to be a vasopressin V2 receptor antagonist and could probably be effective against hypertensive heart failure and could also be an effective renal protective agent. Synonyms: Tolvaptan-D7; N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide-d7; OPC 41061-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1246818-18-7. Molecular formula: C26H18D7ClN2O3. Mole weight: 455.98. | |
| Topiramate | Topiramate is a kainate GluR5 receptor antagonist, originally used as an anticonvulsant. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate. Grade: >98%. CAS No. 97240-79-4. Molecular formula: C12H21NO8S. Mole weight: 339.37. | |
| Topiramate-[13C6] | An isotope labelled of Topiramate. Topiramate is an anticonvulsant drug. Synonyms: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl-3a,5,5a,8a,8b-13C5)methyl-13C sulfamate. Grade: 98% by CP. CAS No. 1217455-55-4. Molecular formula: C6[13C]6H21NO8S. Mole weight: 345.32. | |
| Topiramate-[d12] | An isotope labelled form of Topiramate. Topiramate is an anticonvulsant drug. It can be used for the treatment of epilepsy. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fuctopyranose-d12 1-Sulfamate; Epitoma-d12; Epitomax-d12; McN 4853-d12; RWJ 17021-d12; TPM-d12; Topamac-d12; Topamax-d12; Topimax-d12; Topina-d12; Topomax-d12. Grade: 98% by HPLC; 99% atom D. CAS No. 1279037-95-4. Molecular formula: C12H9D12NO8S. Mole weight: 351.44. | |
| Topotecan | Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-; (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-; (S)-Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Evotopin; Hycamptamine; Hycamptin; Nogitecan; NSC 609699; Potactasol; SKF 104864; SKF-S 104864; TopoCED; Topophore C; Topotecan lactone; ZINC 1611274. Grade: ≥95%. CAS No. 123948-87-8. Molecular formula: C23H23N3O5. Mole weight: 421.45. | |
| Topotecan-[d5] | Topotecan-[d5] is the labelled analogue of Topotecan. Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Labelled topotecan (t542500). a dna topoisomerase i inhibitor; semisynthetic analog of camptothecin. antineoplastic. Synonyms: Topotecan D5. Grade: 95% atom D. CAS No. 1133355-98-2. Molecular formula: C23H18D5N3O5. Mole weight: 426.48. | |
| Topotecan-[d6] | One isotopic labelled form of Topotecan, which is a topoisomerase I inhibitor and has been found to be an effective antineoplastic agent. Synonyms: (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4',6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6. Grade: 95% by HPLC; 98% atom D. CAS No. 1044904-10-0. Molecular formula: C23H17D6N3O5. Mole weight: 427.48. | |
| Topotecan hydrochloride | Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Topoisomerase i inhibitors. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze. Grade: >98%. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. | |
| Torsemide-[d7] | Torsemide-[d7] is the labelled analogue of Torsemide, an anilinopyridine sulfonylurea derivative and has been found to be used as an diuretic agent. Synonyms: Torsemide D7; N-[[(1-Methylethyl-d7)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide. Grade: 95% by HPLC; 98% atom D. CAS No. 1189375-06-1. Molecular formula: C16H13D7N4O3S. Mole weight: 355.46. | |
| Trametinib-[d4] | One of the isotopic labelled form of Trametinib, which has been found to be an EGFR kinase inhibitor and could be used against advanced cutaneous melanoma. Synonyms: N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide-d4; G 02442104-d4; GSK 1120212-d4; JTP 74057-d4. Grade: >98%. Molecular formula: C26H19D4FIN5O4. Mole weight: 619.42. | |
| Trametinib-[d6] | One of the impurities of Trametinib, which has been found to be an EGFR kinase inhibitor and could be used against advanced cutaneous melanoma. Synonyms: N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl-2,4,5,6-d4]-acetamide-2,2-d2. Grade: 95% by HPLC; 98% atom D. Molecular formula: C26H17D6FIN5O4. Mole weight: 621.44. | |
| Trandolaprilat-[d5] | Trandolaprilat-[d5] is the labelled analogue of Trandolaprilat, which is a metabolite of Trandolapril. Trandolapril has been found to be an ACE inhibitor and could be used as an antihypertensive agent. Synonyms: Trandolaprilat-phenyl-d5; (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 1356841-27-4. Molecular formula: C22H25D5N2O5. Mole weight: 407.51. | |
| Trandolapril-[d5] | Trandolapril-[d5] is the labelled analogue of Trandolapril, which has been found to be an ACE inhibitor and could be used as an antihypertensive agent. Synonyms: Trandolapril D5; (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-(phenyl-d5)propyl]amino]-1-oxopropyl]octahydro-1H-Indole-2-carboxylic Acid. Grade: 98% HPLC. CAS No. 1356847-98-7. Molecular formula: C24H29D5N2O5. Mole weight: 435.57. | |
| Tranexamic-[d2] Acid (aminomethyl-[d2]) | An isotope labelled of Tranexamic acid. Tranexamic acid can be used to treat or prevent excessive blood loss from major trauma, post partum bleeding, surgery, heavy menstruation and so on. Synonyms: (1R,4R)-4-(Aminomethyl)cyclohexane-1-carboxylic-1,2-d2 acid. Grade: 98% by HPLC; 98% atom D. Molecular formula: C3H13D2NO2. Mole weight: 159.22. | |
| (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane | Trans-BTP Dioxolane is a PAF receptor antagonist. This compound demonstrates competitive antagonism of PAF in a rabbit washed platelet assay (Ki = 0.3 μM). Synonyms: trans-BTP Dioxolane; trans-(±)-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane; (2R,4R)-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane. Grade: ≥98%. CAS No. 116673-45-1. Molecular formula: C21H26O8. Mole weight: 406.4. | |
| (-)-trans 3'-Aminomethyl Nicotine | (-)-trans 3'-Aminomethyl Nicotine is one of Nicotine derivatives, which is a potent parasympathomimetic stimulant. Synonyms: 3-Pyrrolidinemethanamine, 1-methyl-2-(3-pyridinyl)-, (2S,3R)-; (2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinemethanamine; (2S,3R)-1-Methyl-2-(3-pyridyl)pyrrolidine-3-methanamine; 1-[(2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinyl]methanamine. CAS No. 272124-60-4. Molecular formula: C11H17N3. Mole weight: 191.27. | |
| trans-3'-Hydroxy Cotinine-[d3] | trans-3'-Hydroxy Cotinine-[d3] is a labelled impurity of Cotinine. Cotinine, a metabolite of nicotine, is potentially to be a therapy of mental diseases, including depression, PTSD, schizophrenia, Alzheimer's disease and Parkinson's disease. Synonyms: trans-3-Hydroxy-1-(methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone. Grade: > 95%. CAS No. 159956-78-2. Molecular formula: C10H9N2O2D3. Mole weight: 195.23. | |
| (±)-trans-4-Cyclohexene-1,2-dicarboxylic acid | (±)-trans-4-Cyclohexene-1,2-dicarboxylic acid is a multifaceted compound extensively employed in the research of specific interventions targeting afflictions encompassing cancer, inflammation and neurological disorders. Eminent for its pharmaceutical prospects, this acid embodies an invaluable instrument for scholars and practitioners operating in the research of compound. Synonyms: (1R,2R)-cyclohex-4-ene-1,2-dicarboxylic acid. CAS No. 15573-40-7. Molecular formula: C8H10O4. Mole weight: 170.16. | |
| trans-4-Hydroxy-L-proline-[2,5,5-d3] | Trans-4-Hydroxy-L-proline-[2,5,5-d3] is a labelled trans-4-Hydroxy-L-proline. Trans-4-Hydroxy-L-proline is a hydroxylated derivative of amino acid proline in the class of non-proteinogenic amino acids. Synonyms: (2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic acid-d3; H-L-Hyp-OH-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1356016-86-8. Molecular formula: C5H6D3NO3. Mole weight: 134.15. | |
| trans-4-Phenyl-3-buten-2-one-[1,1,1,3-d4] | Trans-4-Phenyl-3-buten-2-one-[1,1,1,3-d4] is one of the labelled impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: benzalacetone-d4; benzylideneacetone-d4. Grade: 97% atom D. CAS No. 130208-38-7. Molecular formula: C10H6D4O. Mole weight: 150.21. | |
| trans-4-Phenyl-3-buten-2-one-[d10] | Trans-4-Phenyl-3-buten-2-one-[d10] is one of the labelled impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: benzalacetone-d10; benzylideneacetone-d10. Grade: 97% atom D. CAS No. 307496-22-6. Molecular formula: C10D10O. Mole weight: 156.25. | |
| trans-Abacavir-[d4] Hydrochloride | trans-Abacavir-[d4] Hydrochloride is a deuterium labelled trans-Abacavir hydrochloride, which is an impurity of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: (1R,4R)-rel-4-[2-Amino-6-[cyclopropyl-d4)amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol Hydrochloride. CAS No. 1346605-40-0. Molecular formula: C14H15D4ClN6O. Mole weight: 326.82. | |
| (±)-trans-ACPD | (±)-trans-ACPD has been found to be a mGluR2 agonist. Uses: Neuroprotective agents. Synonyms: (±)-1-Aminocyclopentane-trans-1,3-dicarboxylic acid. Grade: ≥99% by HPLC. CAS No. 67684-64-4. Molecular formula: C7H11NO4. Mole weight: 173.17. | |
| (+)-trans-anti-BPDE-N2-dG | (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts. Synonyms: (+)-trans-anti-Benzo[a]pyrene-dG; 10S(+)-trans-anti-[Py]-N2-dG; [7R-(7α,8β,9β,10α)]-2'-deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine; Benzo[a]pyrene, guanosine deriv.; (+)-r-7,t-8-Dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene-dG; (+)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene. CAS No. 65437-20-9. Molecular formula: C30H27N5O7. Mole weight: 569.56. | |
| (+)-trans-anti-BPDE-N2-dG-d8 | Isotope labelled (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound is used to obtain a better understanding of the effects of carcinnogen-DNA adducts. Synonyms: (+)-trans-anti-Benzo[a]pyrene-dG-d8; 10S(+)-trans-anti-[Py]-N2-dG-d8; [7R-(7α,8β,9β,10α)]-2'-deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-d8; (+)-r-7,t-8-Dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene-dG-d8; (+)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-d8. Molecular formula: C30H19D8N5O7. Mole weight: 577.61. | |
| (-)-trans-anti-N2-BPDE-dG | (-)-trans-anti-N2-BPDE-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Synonyms: [7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine; Benzo[a]pyrene, guanosine deriv.; (-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene. CAS No. 85026-87-5. Molecular formula: C30H27N5O7. Mole weight: 569.56. | |
| (+/-)-trans-anti-N2-BPDE-dG-15N5 | (+/-)-trans-anti-N2-BPDE-dG-15N5 is an isotope labelled analog of (-)-trans-anti-N2-BPDE-dG, which is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Synonyms: [7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-15N5; (+/-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-15N5. Molecular formula: C30H29[15N]5O7. Mole weight: 576.55. | |
| (-)-trans-anti-N2-BPDE-dG-d8 | Isotope labelled (-)-trans-anti-N2-BPDE-dG-d8 is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Synonyms: [7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-d8; (-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-d8. Molecular formula: C30H19D8N5O7. Mole weight: 577.61. | |
| trans-Capsaicin-[d3] | A labelled Capsaicin analogue. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Synonyms: (6E)-N-[(4-hydroxy-3-(methoxy-d3)phenyl)methyl]-8-methyl-6-nonenamide; (E)-8-Methyl-N-vanillyl-6-nonenamide-d3; Capsaicin-d3; (E)-N-(4-Hydroxy-3-(methoxy-d3)benzyl)-8-methylnon-6-enamide; ALGRX 4975-d3; Adlea-d3; Axsain-d3; Capsaicine-d3; Capsin P 50-d3. Grade: > 95%. CAS No. 1217899-52-9. Molecular formula: C18H27D3NO3. Mole weight: 308.44. | |
| trans-Chalcone | Trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity. Trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. Trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. Synonyms: Chalcone; (E)-Chalcone; Benzalacetophenone; Benzylideneacetophenone; (2E)-1,3-diphenylprop-2-en-1-one. Grade: ≥97%. CAS No. 614-47-1. Molecular formula: C15H12O. Mole weight: 208.26. | |
| trans-Chalcone-[d12] | trans-Chalcone-[d12]. Synonyms: benzylideneacetophenone-d12. Grade: 98% atom D. CAS No. 307496-21-5. Molecular formula: C15D12O. Mole weight: 220.33. | |
| trans-Cinnamic acid-[β,2,3,4,5,6-d6] | Trans-Cinnamic acid-[β,2,3,4,5,6-d6] is an isotopic analogue of Trans-cinnamic acid. Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and stimulating insulin secretion in vitro. Synonyms: 3-Phenyl-d5-2-propenoic acid-3-d1; (E)-3-Deuterio-3-(2,3,4,5,6-pentadeuteriophenyl)prop-2-enoic Acid. Grade: 98% atom D. CAS No. 91453-04-2. Molecular formula: C9H2D6O2. Mole weight: 154.20. | |
| trans-Cinnamic acid-[d7] | Trans-Cinnamic acid-[d7] is an isotopic analogue of Trans-cinnamic acid. Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and stimulating insulin secretion in vitro. Synonyms: 3-Phenyl-d5-2-propenoic acid-2,3-d2. Grade: 98% atom D. CAS No. 308796-47-6. Molecular formula: C9HD7O2. Mole weight: 155.20. | |
| trans-Cinnamoyl b-D-glucoside | trans-Cinnamoyl b-D-glucoside is a renowned compound, manifesting remarkable antioxidant and anti-inflammatory attributes. Its extraordinary capacity to neutralize detrimental free radicals renders it an indispensable safeguard against oxidative stress. Synonyms: 1-[(2E)-3-Phenyl-2-propenoate]-b-D-Glucopyranose. Grade: 97.5%. CAS No. 40004-96-4. Molecular formula: C15H18O7. Mole weight: 310.30. | |
| trans-Clomiphene-[d5] Hydrochloride | trans-Clomiphene-[d5] Hydrochloride is the labelled analogue of trans-Clomiphene Hydrochloride, which is a trans isomer of Clomiphene. Synonyms: (E)-2-[p-[2-chloro-(1,2-diphenyl-d5)vinyl]phenoxy]-triethylamine Hydrochloride; 2-[4-[(1E)-2-Chloro-(1,2-diphenyl-d5)ethenyl]phenoxy]-N,N-diethyl-ethanamine Hydrochloride; (E)-Clomiphene-d5 Hydrochloide; Enclomifene-d5 Hydrochloride; Enclomiphene-d5 Hydrochloride; trans-Clomiphene-d5 Hydrochloride. Grade: >95%. CAS No. 1346606-66-3. Molecular formula: C26H24D5Cl2NO. Mole weight: 447.45. | |
| trans-Ethylene-[1,2-d2] | trans-Ethylene-[1,2-d2]. Synonyms: trans-Ethylene-1,2-D2; (E)-(2H2)Ethene. Grade: 95% atom D. CAS No. 1517-53-9. Molecular formula: C2H2D2. Mole weight: 30.07. | |
| Trans-permethrin-[d6] | Trans-permethrin-[d6]. Synonyms: trans-Permethrin D6 (dimethyl D6). Grade: 95% atom D. CAS No. 82523-59-9. Molecular formula: C21H14D6Cl2O3. Mole weight: 397.33. | |
| trans-Stilbene-[a,a-d2] | trans-Stilbene-[a,a-d2]. Synonyms: trans-Stilbene-a,a D2; 1,1'-(E)-(2H2)-1,2-Ethenediyldibenzene. Grade: 95% atom D. CAS No. 5284-44-6. Molecular formula: C14H10D2. Mole weight: 182.26. | |
| trans-Stilbene-[d10] | trans-Stilbene-[d10]. Synonyms: trans-Stilbene-d10 (rings-d10). Grade: 95% atom D. CAS No. 20748-24-7. Molecular formula: C14H2D10. Mole weight: 190.31. | |
| trans-Stilbene-[d12] | trans-Stilbene-[d12]. Synonyms: trans-Stilbene-d12. Grade: 95% atom D. CAS No. 16341-52-9. Molecular formula: C14D12. Mole weight: 192.32. | |
| trans-Styrene-[β-d] | trans-Styrene-[β-d]. Synonyms: 8-deuterostyrene; cis-8-deuteriostyrene; (Z)-(beta-2H)Styrene. Grade: ≥98% by CP; ≥94% atom D. CAS No. 6911-81-5. Molecular formula: C8H7D. Mole weight: 105.16. | |
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