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Scopine
Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. Grade: >98%. CAS No. 498-45-3. Molecular formula: C8H13NO2. Mole weight: 155.19.
SCOPOLAMINE N-OXIDE HYDROBROMIDE
Scopolamine N-Oxide is a muscarinic antagonist that inhibits binding at the acetylcholine receptors. Uses: Anticholinergic agent. Synonyms: Hyoscine N-oxide hydrobromide; Scopolamine aminoxide hydrobromide. Grade: ≥98.0% (HPLC). CAS No. 6106-81-6. Molecular formula: C17H22BrNO5. Mole weight: 400.3.
(±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes. Uses: Cardiotonic agents. Synonyms: DPI 201-106; 4-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy]-1H-indole-2-carbonitrile. Grade: ≥98%. CAS No. 97730-95-5. Molecular formula: C29H30N4O2. Mole weight: 466.6.
Secnidazole-[13C2,15N2]
Secnidazole-[13C2,15N2] is a labelled Secnidazole. Secnidazole is a nitroimidazole anti-infective. Synonyms: 1-(2-Methyl-5-nitroimidazol-2-13C-1,3-15N-1-yl)-propan-2-ol. Grade: 95% by HPLC; 98% atom 13C, 15N. Molecular formula: C5[13C]2H11N[15N]2O3. Mole weight: 189.00.
Serotonin-[d4]
Serotonin-[d4] is the labelled analogue of serotonin. Serotonin is a monoamine neurotransmitter and popularly thought to be a contributor to feelings of well-being and happiness. Synonyms: Serotonin D4. Grade: 95% by HPLC; 95% atom D. CAS No. 58264-95-2. Molecular formula: C10H8D4N2O. Mole weight: 180.24.
Sertaconazole
Sertaconazole is a potent antifungal compound primarily employed in the research of various fungal infections such as vaginal candidiasis, tinea pedis (athlete's foot), tinea cruris (jock itch) and tinea corporis (ringworm). Uses: An imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi. Synonyms: Demofix; 1-(2-((7-Chlorobenzo[b]thiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole; 7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene; (±)-1-[2,4-Dichloro-β-[(7-chlorobenzo[b]thien-3-yl)methoxy]phenethyl]imidazole. Grade: ≥95%. CAS No. 99592-32-2. Molecular formula: C20H15Cl3N2OS. Mole weight: 437.77.
Sertindole-[d4]
Sertindole-[d4] is the labelled analogue of Sertindole. Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Synonyms: Sertindole-d4; 1-[2-[4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone-d4; Serdolect-d4; Zerdol-d4. CAS No. 168274-67-7. Molecular formula: C24H22D4ClFN4O. Mole weight: 444.97.
Sertraline-[13C,15N,d3]
One of the isotope labelled form of sertraline, which is a selective serotonin reuptake inhibitor (SSRI) and could be used in the treatment of depression. Synonyms: (1S,4S)-4-(3,4-Dichlorophenyl)-N-(methyl-13C-d3)-1,2,3,4-tetrahydronaphthalen-1-amine-13N; Sertraline-13C,15N,D3; Sertraline-15N-13C-d3. Grade: >95%. Molecular formula: C16[13C]H14D3Cl2[15N]. Mole weight: 311.24.
Sertraline-[d3] Hydrochloride
Isotopic labelled sertraline hydrochloride. Sertraline hydrochloride is a selective serotonin reuptake inhibitor (SSRI) for the treatment of depression. Synonyms: 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine-d3 Hydrochloride; rac Sertraline-d3 Hydrochloride. Grade: > 95%. CAS No. 1217741-83-7. Molecular formula: C17H15D3Cl3N. Mole weight: 345.71.
Sertraline-[d6]
One of the isotope labelled form of sertraline, which is a selective serotonin reuptake inhibitor (SSRI) and could be used in the treatment of depression. Synonyms: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine-d6; Sertraline D6; (1S,4S)-4-(3,4-Dichlorophenyl-2,5,6-d3)-N-(methyl-d3)-1,2,3,4-tetrahydronaphthalen-1-amine. Grade: >95%. CAS No. 2747914-71-0. Molecular formula: C17H11D6Cl2N. Mole weight: 312.27.
Sesamol-[d3]
Sesamol-[d3]. Synonyms: Sesamol D3; (4,6,7-2H3)-1,3-Benzodioxol-5-ol. Grade: 98% atom D. CAS No. 1219798-37-4. Molecular formula: C7H3D3O3. Mole weight: 141.14.
Sevedindione
Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine. Synonyms: Sevedindione; Prestwick_183; CHEMBL4759213; (1S,2R,6R,10R,14R,15R,18S,23R)-14-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosane-17,20-dione. Grade: 95 % (TLC). Molecular formula: C27H41NO3. Mole weight: 427.62.
Sevoflurane-[d3]
Sevoflurane-[d3] is the labelled analogue of Sevoflurane. Synonyms: 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane-d3. Grade: 97% by CP; 98% atom D. CAS No. 1173021-96-9. Molecular formula: C4D3F7O. Mole weight: 203.07.
SG2057
SG2057 is a pentyldioxy linked PBD dimer which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts, and also mono-adducts depending on sequence. SG2057 has multilog differential in vitro cytotoxicity against a panel of human tumour cell lines with a mean GI(50) of 212 pM. The agent is highly efficient at producing DNA interstrand cross-links in cells which form rapidly and persist over a 48h period. Cures were obtained in a LOX-IMVI melanoma model following a single administration and dose-dependent activity, including regression responses, observed in SKOV-3 ovarian and HL-60 promyelocytic leukemia models following repeat dose schedules. In the advanced stage LS174T model, SG2057 administered either as a single dose, or in two repeat dose schedules, was superior to irinotecan. SG2057 is therefore a highly active antitumor agent, with more potent in vitro activity and superior in vivo activity to SG2000. Synonyms: SG-2057; SG 2057; DRG-16; (11aS,11a'S)-8,8'-(pentane-1,5-diylbis(oxy))bis(7-methoxy-2-methylene-2,3-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5(11aH)-one). CAS No. 260417-62-7. Molecular formula: C33H36N4O6. Mole weight: 584.66.
S-Hydroxychloroquine-[d4]
A labelled analogue of Hydroxychloroquine. Hydroxychloroquine is a medication used for the treatment of certain malaria. Synonyms: (S)-2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino-d4]ethanol. Grade: >98%. Molecular formula: C18H22D4ClN3O. Mole weight: 339.89.
Silodosin
Silodosin shows high selectivity for the alpha(1A)-AR subtype. Synonyms: KMD-3213; KMD3213; KMD 3213; KAD 3213; KAD 3213; KAD3213; Silodosin. trade names Rapaflo, Silodyx, Rapilif, Silodal, Urief, Urorec. Grade: >98%. CAS No. 160970-54-7. Molecular formula: C25H32F3N3O4. Mole weight: 495.53.
Silodosin-[d4]
Silodosin-[d4] is the labelled analogue of silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: Silodosin D4; 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide-d4; (R)-1-(3-Hydroxypropyl)-5-[2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]indoline-7-carboxamide-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1426173-86-5. Molecular formula: C25H28D4F3N3O4. Mole weight: 499.56.
Silodosin-[d4] β-D-Glucuronide Sodium Salt
An isotope labelled metabolite of Silodosin. Silodosin is an α1-adrenoceptor antagonist. It can be used for symptomatic treatment of benign prostatic hyperplasia. Synonyms: Sodium (2S,3S,4S,5R,6R)-6-(3-(7-carbamoyl-5-((R)-2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl-1,1,2,2-d4)amino)propyl)indolin-1-yl)propoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate; Silodosin-D4 β-D-Glucuronide Sodium Salt; Silodosin-d4 beta-D-Glucuronide Sodium Salt; 3-[7-(Aminocarbonyl)-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indol-1-yl]propyl-d4 β-D-Glucopyranosiduronic Acid Monosodium Salt. Grade: 95% by HPLC; 98% atom D. Molecular formula: C31H35D4F3N3NaO10. Mole weight: 697.67.
Silodosin-[d6]
Silodosin-[d6] is the labelled analogue of Silodosin. Silodosin is an α1-adrenoceptor antagonist. It can be used for symptomatic treatment of benign prostatic hyperplasia. Synonyms: Silodosin D6; 2,3-Dihydro-1-(3-hydroxypropyl-d6)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide; (R)-1-(3-Hydroxypropyl-d6)-5-[2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]indoline-7-carboxamide. Grade: 95% by HPLC; 98% atom D. CAS No. 1051374-52-7. Molecular formula: C25H26D6F3N3O4. Mole weight: 501.57.
Silodosin Metabolite-[d4]
An isotope labelled impurity of Silodosin. Silodosin is an α1-adrenoceptor antagonist for the treatment of benign prostatic hypertrophy. Synonyms: 3-(7-carbamoyl-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indolin-1-yl)propanoic acid-d4. Grade: > 95%. Molecular formula: C25H26D4F3N3O5. Mole weight: 513.54.
(-)-Silvestrol
A member of flavagline family of natural products from the genus of Aglaia, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7; 5'myc-UTR-LUC inhibtior with IC50 of 0.8 nM. Uses: Induces early autophagy and apoptosis in human melanoma cells. Synonyms: Methyl (1R,2R,3S,3aR,8bS)-6-({(2S,3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl}oxy)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d] furan-2-carboxylate. Grade: ≥95%. CAS No. 697235-38-4. Molecular formula: C34H38O13. Mole weight: 654.66.
Simazine-[d10]
Simazine-[d10] is the labelled analogue of Simazine. Simazine is an herbicide used for control of broad-leaved weeds and annual grasses. Synonyms: Simazine D10; 6-Chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine-d10; 2-Chloro-4,6-bis(ethylamino)-s-triazine-d10. Grade: 95% by HPLC; 98% atom D. CAS No. 220621-39-6. Molecular formula: C7H2D10ClN5. Mole weight: 211.72.
Simazine-[d5]
Simazine-[d5]. Synonyms: Simazine D5 (ethyl D5); 6-Chlor-N-ethyl-N'-(2H5)ethyl-1,3,5-triazin-2,4-diamin. Grade: 95% atom D. CAS No. 220621-41-0. Molecular formula: C7H7D5ClN5. Mole weight: 206.69.
Simvastatin-[d11]
An isotope labelled of Simvastatin. Simvastatin is a lipid-lowering medication as a competitive inhibitor of HMG-CoA reductase. Synonyms: Simvastatin-d11 (2,2-dimethylbutyrate-d11). Grade: 95% by HPLC; 98% atom D. CAS No. 1002347-74-1. Molecular formula: C25H27D11O5. Mole weight: 429.64.
Simvastatin-[d3]
An isotope labelled of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Synonyms: Simvastatin D3 lactone. Grade: 95% by HPLC; 98% atom D. CAS No. 1002347-61-6. Molecular formula: C25H35D3O5. Mole weight: 421.58.
Simvastatin-[d6]
An isotope labelled Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro -3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl] -1-naphthalenyl Ester; (+)-Simvastatin-d6; Cholestat-d6; Lipex-d6; Novo-Simvastatin-d6; Simvotin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; Zorced-d6. Grade: >95%. CAS No. 1002347-71-8. Molecular formula: C25H32D6O5. Mole weight: 424.61.
Simvastatin hydroxy acid-[d3] ammonium salt
An isotope labelled metabolite of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Synonyms: (1S,3R,7S,8S,8aR)-8-((3R,5R)-3,5-dihydroxy-7-(lambda1-oxidanyl)-7-oxoheptyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methyl-2-(methyl-d3)butanoate compound with lambda4-azane (1:1). Grade: 95% by HPLC; 98% atom D. Molecular formula: C25H40D3NO6. Mole weight: 456.63.
Simvastatin hydroxyl acid-[d6] Sodium salt
One of the isotope labelled impurities of Simvastatin, which is an inhibitor of HMG-CoA reductase. Synonyms: Simvastatin hydroxyl acid-d6 Sodium salt; (3R,5R)-7-((1S,2S,6R,8S,8aR)-8-((2,2-Bis(methyl-d3)butanoyl)oxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoic acid sodium salt. Grade: >98%. CAS No. 2747915-76-8. Molecular formula: C25H33D6NaO6. Mole weight: 464.61.
Sitafloxacin
Sitafloxacin, a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections. Synonyms: 7-((S)-7-amino-5-azaspiro[24]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; DU 6859; DU-6859; DU6859; DU 6859A; DU-6859A; DU6859A; Sitafloxacin; Sitafloxacin hydrate, Sitafloxacin anhydrous, Trade name: Gracevit. Grade: >98%. CAS No. 127254-12-0. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.81.
Sitagliptin-[d4]
An isotope labelled Sitagliptin. Sitagliptin, marketed as the phosphate salt, is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (3R)-3-amino-1-[3-(trifluoromethyl)(5,5,6,6-D4)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; (R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine D4. Grade: >98%. CAS No. 1426173-93-4. Molecular formula: C16H11D4F6N5O. Mole weight: 411.34.
(±)-Sitagliptin-d4 hydrochloride
(±)-Sitagliptin-d4 is intended for use as an internal standard for the quantification of sitagliptin by GC- or LC-MS. Sitagliptin i and (+)-sitagliptin, also known as sitagliptin impurity E, a potential impurity found in commercial preparations of (-)-sitagliptin. Synonyms: 3-amino-1-[5,6-dihydro-5,6-d2-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl-5,6-d2]-4-(2,4,5-trifluorophenyl)-1-butanone monohydrochloride. Grade: ≥99% atom D. Molecular formula: C16H11D4F6N5O·HCl. Mole weight: 447.80.
Sitagliptin phosphate
Sitagliptin phosphate is the phosphate salt form of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Uses: Hypoglycemic agents. Synonyms: (2R)-4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate salt; MK-431; ONO-5435. Grade: >98%. CAS No. 654671-78-0. Molecular formula: C16H15F6N5O.H3O4P. Mole weight: 505.31.
S-(+)-Manidipine-[d4]
S-(+)-Manidipine-[d4] is the labelled (S)-Manidipine enantiomer. Manidipine is a calcium channel inhibitor used as an antihypertensive. Synonyms: (4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl-d4 Methyl Ester; (+)-Manidipine-d4. Grade: > 95%. CAS No. 1217836-12-8. Molecular formula: C35H34N4O6D4. Mole weight: 614.72.
S-methyl DM1
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds tubulin with a Kd of 0.93 μM and inhibits microtubule polymerization. S-methyl DM1 can effectively inhibit microtubule dynamic instability and has anticancer effects. Synonyms: N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine; [(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-methylsulfanylpropanoyl)amino]propanoate. CAS No. 912569-84-7. Molecular formula: C36H50ClN3O10S. Mole weight: 752.31.
S-Methyl-thioacetaminophen-[d3]
S-Methyl-thioacetaminophen-[d3]. Uses: A labelled metabolite of acetaminophen. Synonyms: S-Methyl-d3-thioacetaminophen. Grade: 95% atom D. CAS No. 1215669-56-9. Molecular formula: C9H8D3NO2S. Mole weight: 200.27.
SN-38-[d3]
SN-38-[d3] is a labelled analogue of SN-38. SN-38 is the active metabolite of irinotecan. Uses: Labelled sn-38, a metabolite of irinotecan, a dna topoisomerase inhibitor. Synonyms: SN-38 D3. Grade: 95% atom D. CAS No. 718612-49-8. Molecular formula: C22H17D3N2O5. Mole weight: 395.42.
(S)-N-Glycidylphthalimide
(S)-N-Glycidylphthalimide is an impurity of Rivaroxaban, a factor Xa (FXa) inhibitor used for the prevention and treatment of thromboembolic disorders. Synonyms: 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-oxiranylmethyl]-; 1H-Isoindole-1,3(2H)-dione, 2-(oxiranylmethyl)-, (S)-; 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-oxiranylmethyl]-; 2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione; (S)-2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione; (S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione; (S)-2-[(Oxiranyl)methyl]isoindole-1,3-dione; (S)-Glycidyl Phthalimide; (S)-N-(2,3-Epoxypropan-1-yl)phthalimide; (S)-N-(2,3-Epoxypropyl)phthalimide; (S)-N-Giycidylphthalimide; 2-[(S)-2-Oxiranylmethyl]-1H-isoindol-1,3(2H)-dione; N-((2S)-Oxiran-2-ylmethyl)phthalimide; N-(S)-Glycidylphthalimide; N-[(+)-Glycidyl]phthalimide; N-[(S)-(+)-Glycidyl]phthalimide; (S)-(+)-N-(2,3-Epoxypropyl)phthalimide. Grade: ≥95%. CAS No. 161596-47-0. Molecular formula: C11H9NO3. Mole weight: 203.19.
S-(+)-O-Desmethyl-Venlafaxine-[d6]
(S)-(+)-O-Desmethyl Venlafaxine-[d6] is the deuterium labelled (S)-(+)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Synonyms: HY-B0602S1; CS-0131892. Grade: 95%. CAS No. 1062609-99-7. Molecular formula: C16H19D6NO2. Mole weight: 269.37.
Sodium 17beta-Estradiol 3-Sulfate-[2,4,16,16-d4]
Sodium 17beta-Estradiol 3-Sulfate-[2,4,16,16-d4] is the labelled analogue of Sodium 17beta-Estradiol 3-Sulfate, which is a derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Synonyms: Estradiol Sulphate D4 sodium; Sodium 17beta-Estradiol-2,4,16,16-d4 3-Sulfate; Sodium 17beta-estradiol sulfate-d4; 17beta-Estradiol 3-O-Sulfate Sodium Salt-d4; beta-Estradiol 3-sulfate sodium salt-d4; 1,3,5(10)-Estratriene-3,17beta-diol 3-sulfate-d4. Grade: ≥95%; ≥98% atom D. CAS No. 352431-50-6. Molecular formula: C18H19D4NaO5S. Mole weight: 378.45.
Sodium Ethyl-[d5] Sulfate
An isotope labelled metabolite of ethanol in humans. Synonyms: Sodium Ethyl-D5 Sulfate. Grade: 98% by HPLC; 99% atom D. CAS No. 1329611-05-3. Molecular formula: C2D5NaO4S. Mole weight: 153.14.
Labelled Sodium pyruvate. Sodium pyruvate is the end product of glycolysis and is used for further metabolic cycles to provide energy for cells. Synonyms: 2-Oxopropanoic Acid-2-13C, Sodium Salt; Pyruvic Acid-2-13C Sodium Salt; Sodium α-Ketopropionate-2-13C. Grade: 95%; 99% atom 13C. CAS No. 87976-70-3. Molecular formula: C2[13C]H3NaO3. Mole weight: 111.04.
Sofosbuvir-[13C,d3]
Sofosbuvir-[13C,d3] is the labelled analogue of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Sofosbuvir 13CD3. Grade: 95% by HPLC; 95% atom 13C; 95% atom D. CAS No. 2070009-25-3. Molecular formula: C21[13C]H26D3FN3O9P. Mole weight: 533.46.
Sofosbuvir-[d6]
Sofosbuvir-[d6] is the labelled analogue of Sofosbuvir. Sofosbuviis a medication used for the treatment of hepatitis C. Synonyms: Sofosbuvir D6; N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-(Methyl-d3)ethyl-2,2,2-d3 Ester. Grade: 95% by HPLC; 98% atom D. CAS No. 1868135-06-1. Molecular formula: C22H23D6FN3O9P. Mole weight: 535.49.
Sofosbuvir metabolite GS331007-[13C,d3]
An isotope labelled metabolite of Sofosbuvir. Sofosbuviis a medication used for the treatment of hepatitis C. Grade: 95% by HPLC; 98% atom D;98% atom 13C. CAS No. 1256490-42-2. Molecular formula: C9[13C]H10D3FN2O5. Mole weight: 264.23.
Sofosbuvir metabolite GS-566500-[13C,d3]
An isotope labelled impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2S)-2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic-13CD3 Acid; O-Desisopropyl O-Desphenyl Sofosbuvir-13C,D3; PSI 352707-13C,D3. Grade: > 95%. CAS No. 1256490-46-6. Molecular formula: [13C]C12H16FN3O9PD3. Mole weight: 415.29.
Solid Chemical phosphorylation reagent II
Solid Chemical phosphorylation reagent II is a click chemistry reagent for the synthesis of oligonucleotides possessing 5'-terminal phosphate residues. Synonyms: Chemical phosphorylation amidite; [3-(4,4'-Dimethoxytrityloxy)-2,2-dicarboxymethylamido]propyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-(methylamino)-2-[(methylamino)carbonyl]-3-oxopropyl 2-cyanoethyl ester; Solid Chemical Phosphorylation Reagent 2; 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(methylamino)-2-(methylcarbamoyl)-3-oxopropyl(2-cyanoethyl)(N,N-diisopropyl)phosphoramidite. Grade: ≥95%. CAS No. 202284-84-2. Molecular formula: C37H49N4O7P. Mole weight: 692.79.
Solifenacin-[d5]
Solifenacin-[d5] is the labelled analogue of Solifenacin. Solifenacin is a drug used to treat contraction of overactive bladder. Synonyms: Solifenacin D5. Grade: 95% by HPLC; 98% atom D. CAS No. 1401416-00-9. Molecular formula: C23H21D5N2O2. Mole weight: 367.5.
Solifenacin-[d5] Hydrochloride
Solifenacin-[d5] Hydrochloride is the labelled analogue of Solifenacin. Solinasine is a drug used to treat contraction of overactive bladder. Synonyms: Solifenacin D5 Hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1426174-05-1. Molecular formula: C23H22D5ClN2O2. Mole weight: 403.96.
Sorafenib
Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. Synonyms: BAY 43-9006. Grade: >98%. CAS No. 284461-73-0. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.82.
Sorafenib-[d3]
Sorafenib-[d3] is the labelled analogue of Sorafenib, which is a potent RAF kinase inhibitor and an antineoplastic. Synonyms: Sorafenib-d3; Sorafenib-(methyl-d3); 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-(methyl-d3)-2-pyridinecarboxamide. Grade: ≥98%; ≥99% atom D. CAS No. 1130115-44-4. Molecular formula: C21H13D3ClF3N4O3. Mole weight: 467.84.
Sorafenib-[d4]
Sorafenib-[d4] is the labelled analogue of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: Sorafenib-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1207560-07-3. Molecular formula: C21H12D4ClF3N4O3. Mole weight: 468.85.
(-)-Sparteine sulfate pentahydrate
(-)-Sparteine sulfate pentahydrate is an alkaloid compound which could be used as in the treatment of antiarrhythmic by blocking sodium channel. Uses: (-)-sparteine sulfate pentahydrate is an alkaloid compound which could be used as in the treatment of antiarrhythmic by blocking sodium channel. Synonyms: LUPINIDINE; (-)-LUPINIDINE SULFATE PENTAHYDRATE; LUPINIDINE SULFATE PENTAHYDRATE; (-)-SPARTEINE SULFATE PENTAHYDRATE; SPARTEINE SULFATE PENTAHYDRATE; (-)-SPARTEINE SULFATE SALT PENTAHYDRATE; SPARTEINE SULFATE, CRYSTALLIZED; (-)-Sparteine sulfate pentahydrate. Grade: >99.0%(T). CAS No. 6160-12-9. Molecular formula: C15H26N2.H2SO4.5(H2O). Mole weight: 422.53.
(+)-Sparteine sulfate pentahydrate
(+)-Sparteine sulfate pentahydrate is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. Synonyms: (+)-Lupinidine sulfate pentahydrate. Grade: ≥98%. Molecular formula: C15H38N2O9S. Mole weight: 422.54.
Spermine-butane-[d8] tetrahydrochloride
Labelled spermine tetrahydrochloride. Spermine tetrahydrochloride is a polyamine that binds to and modulates NMDA receptor channel. Spermine also acts as a GluR inhibitor, PLCα inhibitor and PLCδ activator. Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamine-d8(butane-d8) tetrahydrochloride; Spermine-[2H8] 4HCl. Grade: 95% by CP; 97% atom D. CAS No. 1173022-85-9. Molecular formula: C10H22D8Cl4N4. Mole weight: 356.23.
Spiramycin I-[d3]
Spiramycin I-[d3] is an antibiotic substance classified in the erythromycin-carbomycin group. Synonyms: 9-O-[(2R,5S,6R)-5-(Dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]leucomycin V-d3; Foromacidin A-d3; Spiramycin A-d3. Grade: >98%. Molecular formula: C43H71D3N2O14. Mole weight: 846.07.
S-P-MEBZ-L-Cysteine-[15N]
S-P-MEBZ-L-Cysteine-[15N] is a labelled S-p-Methylbenzyl-L-cysteine, which is a derivative of cysteine. Synonyms: H-Cys(4-Mbzl)-OH-15N. Grade: 98% by CP; 98% atom 15N. Molecular formula: C11H15[15N]O2S. Mole weight: 226.30.
S-P-MEBZ-L-Cysteine-[3,3-d2]-N-T-BOC
S-P-MEBZ-L-Cysteine-[3,3-d2]-N-T-BOC is a labelled Boc-S-(4-methylbenzyl)-L-cysteine, which is a protected derivative of cysteine. Synonyms: Boc-Cys(Mbzl)-OH-3,3-D2; Boc-S-(4-methylbenzyl)-L-cysteine-3,3-D2; Boc-L-Cys(pMeBzl)-OH-3,3-D2; Boc-Cys(pMeBzl)-OH-3,3-D2. Grade: 98% by HPLC; 98% atom D. Molecular formula: C16H21D2NO4S. Mole weight: 327.44.
Spongouridine
1-β-D-Arabinofuranosyluracil is an antiviral agent. It is used for the treatment of severe acute respiratory syndrome (SARS). It is also an impurity of Cytarabine. Synonyms: Arauridine; 1-(β-D-Arabinofuranosyl)uracil; Uracil-1-β-D-arabinofuranoside; 1-β-D-Arabinofuranosyl-2,4(1H,3H)-pyrimidinedione; Ara-U; Arabinosyluracil; NSC 68928; Cytarabine Impurity A; Cytarabine EP Impurity A; 1-β-D-Arabinofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Arabinofuranosyluracil; Arabinofuranosyluracil; Spongouridin; Uracil arabinoside; Uracil β-D-arabinofuranoside. Grade: ≥95%. CAS No. 3083-77-0. Molecular formula: C9H12N2O6. Mole weight: 244.20.
Squalane-[d62]
Squalane-[d62]. Synonyms: Squalane-d62; 2,6,10,15,19,23-Hexakis[(2H3)methyl](2H44)tetracosane. Grade: 95% atom D. CAS No. 16514-83-3. Molecular formula: C30D62. Mole weight: 485.2.
Squaric Acid-[d2]
Squaric Acid-[d2] is the labelled analogue of Squaric Acid. Synonyms: Squaric acid-d2; 3,4-Dihydroxy-3-cyclobutene-1,2-dione-d2. Grade: 95% by CP; 98% atom D. CAS No. 31150-56-8. Molecular formula: C4D2O4. Mole weight: 116.07.
S-Sulfo-DL-cysteine-[2,3,3-d3]
S-Sulfo-DL-cysteine-[2,3,3-d3] is a labelled S-Sulfocysteine. S-Sulfocysteine is a potent NMDA-receptor agonist. Synonyms: White to off-white powder. Grade: 98%. CAS No. 2687960-80-9. Molecular formula: C3H4D3NO5S2. Mole weight: 204.24.
Stavudine
Stavudine (d4T) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV. Uses: Anti-hiv agents. Synonyms: 2',3'-Dideoxy-2',3'-didehydrothymidine; D4T; 3'-Deoxy-2'-thymidinene; 3'-Deoxy-2',3'-didehydrothymidine; BMY-27857; Zerit; NSC 163661; Sanilvudine; Virostav; Zidovudine EP Impurity A; 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. Grade: ≥95%. CAS No. 3056-17-5. Molecular formula: C10H12N2O4. Mole weight: 224.21.
Stavudine-[d3]
Stavudine-[d3] is the labelled analogue of Stavudine, which is used as an antiviral and reverse transcriptase inhibitor. Synonyms: Stavudine D3. Grade: 98%; 97.5% atom D. CAS No. 1217619-42-5. Molecular formula: C10H9D3N2O4. Mole weight: 227.23.
Stavudine-[d4]
An isotope labelled Stavudine. Stavudine is an antiretroviral medication used to prevent and treat HIV/AIDS. Synonyms: Stavudine-alpha,alpha,alpha,6-d4. Grade: > 95%. CAS No. 1219803-67-4. Molecular formula: C10H8D4N2O4. Mole weight: 228.24.
Stearic acid-[1-13C]
Stearic acid-[1-13C] is a labelled analogue of Stearic acid. Stearic acid is a saturated long-chain fatty acid, which is found in animal and plant fats, and is a major component of cocoa butter and shea butter. Synonyms: 1-Heptadecanecarboxylic acid-1-13C; Cetylacetic acid-1-13C; Octadecanoic acid-1-13C; Stearophanic acid-1-13C. Grade: 99% by CP; 99% atom 13C. CAS No. 85541-42-0. Molecular formula: C17[13C]H36O2. Mole weight: 285.50.
Stearic acid-[17,17,18,18,18-d5]
Stearic-17,17,18,18,18-[d5] acid is a labelled analogue of Stearic acid. Stearic acid is a saturated long-chain fatty acid, which is found in animal and plant fats, and is a major component of cocoa butter and shea butter. Synonyms: Stearic Acid (17,17,18,18,18-D5); Octadecanoic-17,17,18,18,18-d5 acid; Stearic-17,17,18,18,18-d5 acid; 1-Heptadecanecarboxylic acid-17,17,18,18,18-d5; 1-Octadecanoic acid-17,17,18,18,18-d5. Grade: 98%; 98% atom D. CAS No. 211443-83-3. Molecular formula: C18H31D5O2. Mole weight: 289.51.
Stearic acid-[18,18,18-d3]
Stearic acid-[18,18,18-d3] is a labelled analogue of Stearic acid. Stearic acid is a saturated long-chain fatty acid, which is found in animal and plant fats, and is a major component of cocoa butter and shea butter. Synonyms: Octadecanoic-18,18,18-d3 acid. Grade: 99% by CP; 98% atom D. CAS No. 62163-39-7. Molecular formula: C18H33D3O2. Mole weight: 287.50.
Stearic acid-[2,2-d2]
Stearic acid-[2,2-d2] is a labelled analogue of Stearic acid. Stearic acid is a saturated long-chain fatty acid, which is found in animal and plant fats, and is a major component of cocoa butter and shea butter. Synonyms: Octadecanoic acid-2,2-d2; octadecanoic-2,2-d2 acid. Grade: 98% atom D. CAS No. 19905-58-9. Molecular formula: C18H34D2O2. Mole weight: 286.49.