BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Rivaroxaban EP Impurity F | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. Rivaroxaban is used to treat deep vein thrombosis and pulmonary embolism in adults. Synonyms: 2-Thiophenecarboxylic acid, 5-chloro-; 5-Chloro-2-thiophenecarboxylic acid; 2-Chloro-5-carboxythiophene; 2-Chloro-5-thiophenecarboxylic acid; NSC 14776. Grade: ≥95%. CAS No. 24065-33-6. Molecular formula: C5H3ClO2S. Mole weight: 162.60. |  |
| Rivastigmine-[d6] Tartrate | Rivastigmine D6 Tartrate is a labelled impurity of Rivastigmine. Rivastigmine is a parasympathomimetic or cholinergic drug for the treatment of dementia. Synonyms: (S)-3-(1-(bis(methyl-d3)amino)ethyl)phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxysuccinate. Grade: 98% HPLC. CAS No. 194930-00-2. Molecular formula: C18H22D6N2O8. Mole weight: 406.42. | |
| Rizatriptan benzoate | Rizatriptan Benzoate is a 5-HT1 agonist triptan drug for the treatment of migraine headaches. Synonyms: Rizatriptan Benzoate; MK-462; MK-0462; 2-(5-((1H-1,2,4-TRIAZOL-1-YL)METHYL)-1H-INDOL-3-YL)-N,N-DIMETHYLETHANAMINE BENZOATE; MK 462; rizatriptan benzoate; Maxalt; MK 0462; MK 462. Grade: >98%. CAS No. 145202-66-0. Molecular formula: C22H25N5O2. Mole weight: 391.47. | |
| Rizatriptan-[d6] Benzoate | Rizatriptan-[d6] Benzoate is the labelled analogue of Rizatriptan benzoate. Rizatriptan is a serotonin 5-HT1 receptor agonist ("triptan"). It works by narrowing dilated blood vessels in the brain, relieving migraine headaches. Synonyms: Rizatriptan D6 Benzoate; Benzoic acid-N,N-bis[(2H3)methyl]-2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethan-1-amine. Grade: 95% by HPLC; 95% atom D. CAS No. 1216984-85-8. Molecular formula: C22H19D6N5O2. Mole weight: 397.50. | |
| Rizatriptan N10-Oxide-[d6] | Rizatriptan N10-Oxide-[d6] is the labelled analogue of Rizatriptan N10-Oxide, which is a metabolite of Rizatriptan. Uses: A labelled metabolite of rizatriptan (r545000). Synonyms: Rizatriptan N10-Oxide-d6; Bis[(2H3)methyl]{2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethyl}amine oxide. Grade: 95% atom D. CAS No. 1261392-57-7. Molecular formula: C15H13D6N5O. Mole weight: 291.38. | |
| R-Lercanidipine-[d3] Hydrochloride | R-Lercanidipine-[d3] Hydrochloride is the labelled analogue of R-Lercanidipine Hydrochloride, which is a dihydropyridine calcium channel blocker. Synonyms: R-(-)-Lercanidipine D3 Hydrochloride; R-Lercanidipine-d3 HCl; (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)(methyl-d3)amino]-1,1-dimethylethyl Methyl Ester Hydrochloride. Grade: 95%; ≥98% atom D. CAS No. 1217724-52-1. Molecular formula: C36H39D3ClN3O6. Mole weight: 651.21. | |
| R-(-)-Manidipine-[d4] | R-(-)-Manidipine-[d4] is the labelled (R)-enantiomer of Manidipine. Manidipine is a dihydropyridine calcium channel blocker used as an antihypertensive. Synonyms: R-(-)-Manidipine D4; (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl-d4 Methyl Ester; (-)-Manidipine-d4. Grade: >95%. CAS No. 1217718-54-1. Molecular formula: C35H34D4N4O6. Mole weight: 614.72. | |
| Robenacoxib-[d5] | Robenacoxib-[d5] is the labelled analogue of Robenacoxib. Robenacoxib is a nonsteroidal anti-inflammatory drug used in veterinary medicine. Synonyms: Robenacoxib-d5; 2-(5-(Ethyl-d5)-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic acid. Grade: 95% by HPLC; 98% atom D. CAS No. 2012598-81-9. Molecular formula: C16H8D5F4NO2. Mole weight: 332.31. | |
| Robenidine-[d8] Hydrochloride | Robenidine-[d8] Hydrochloride is a labelled salt of Robenidine. Robenidine is an antibiotic used for control of coccidiosis and protozoa. Synonyms: Robenidine D8 Hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1173097-77-2. Molecular formula: C15H6D8Cl3N5. Mole weight: 378.71. | |
| ROCAGLAMIDE | Rocaglamide is the first cyclopenta[b]benzofuran derivative extracted from Aglaia elliptifolia in 1982 by King and colleagues. Its IC50 value is ~50 nM for the heat shock reporter. It has antileukemic activity and displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. It is an immunosuppressant that inhibits activation of NF-kB and NF-AT. It markedly inhibited tumor growth from Huh-7 cells propagated in severe combined immunodeficient mice. It induces apoptosis in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells. It inhibit protein synthesis without affecting DNA or RNA synthesis. Uses: Rocaglamide has antileukemic activity and displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. it is an immunosuppressant that inhibits activation of nf-kb and nf-at. it inhibit protein synthesis without affecting dna or rna synthesis. Synonyms: Rocaglamide; Rocaglamide A; RocA; NSC 326408. (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide; NSC 326408; Roc-A; Rocaglamide A; 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-; [1R-(1α. Grade: 95%. CAS No. 84573-16-0. Molecular formula: C29H3 | |
| R-(-)-O-Desmethyl Venlafaxine-[d6] | R-(-)-O-Desmethyl-Venlafaxine-[d6] is the labelled analogue of R-(-)-O-Desmethyl-Venlafaxine, a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: (R)-4-(2-(bis(methyl-d3)amino)-1-(1-hydroxycyclohexyl)ethyl)pheno. Grade: 98%. CAS No. 1062609-96-4. Molecular formula: C16H19D6NO2. Mole weight: 269.37. | |
| Roflumilast | Roflumilast has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). While Roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy. Synonyms: BY217; BY-217; BY 217; B 9302-107; B9302-107; B-9302-107; BYK 20869; BYK-20869; BYK20869; Daxas; Daliresp. Grade: 99%. CAS No. 162401-32-3. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.207. | |
| Roflumilast-[d3] | A deuterated Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Daxas-d3; 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. Grade: > 95%. CAS No. 1189992-00-4. Molecular formula: C17H11D3Cl2F2N2O3. Mole weight: 406.23. | |
| Roflumilast-[d4] | One of the isotopic labelled form of Roflumilast, which is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4; Daxas-d4. Grade: >98%. CAS No. 1398065-69-4. Molecular formula: C17H10D4Cl2F2N2O3. Mole weight: 407.23. | |
| Roflumilast N-oxide-[d4] | A deuterated impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Roflumilast-d4 N-Oxide; 3-(Cyclopropylmethoxy-d4)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-(cyclopropyl-d4) methoxybenzamide. Grade: > 95%. CAS No. 1794760-31-8. Molecular formula: C17H10Cl2F2N2O4D4. Mole weight: 423.24. | |
| Roflumilast Related Compound C | A metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast. Synonyms: 4-Amino-3,5-dichloropyridine; 4-Pyridinamine, 3,5-dichloro-; 3,5-Dichloro-4-pyridinamine; Pyridine, 4-amino-3,5-dichloro-; 3,5-Dichloro-4-aminopyridine; 3,5-Dichloropyridin-4-ylamine; 3,5-Dichloropyridine-4-amine. Grade: ≥95%. CAS No. 22889-78-7. Molecular formula: C5H4Cl2N2. Mole weight: 163.01. | |
| Roflumilast Related Compound D | An impurity and intermediate in the preparation of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid; Benzoic acid, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-. Grade: 98%. CAS No. 162401-62-9. Molecular formula: C12H12F2O4. Mole weight: 258.22. | |
| Ronidazole-[d3] | Ronidazole-[d3] is the labelled analogue of Ronidazole, which is an antimicrobial agent. Synonyms: Ronidazole-D3; 2-Carbamoyloxymethyl-1-methyl-D3-5-nitro-1H-imidazole; 1-(Methyl-d3)-5-nitro-1H-imidazole-2-methanol 2-Carbamate; [1-(Methyl-d3)-5-nitroimidazol-2-yl]methyl Carbamate; 1-(Methyl-d3)-2-carbamoyl-oxymethyl-5-nitroimidazole; Dugro-d3; MCMN-d3; Ridzol-d3; Ridzol P-d3; Ridzole-d3; Ronida BT-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1015855-87-4. Molecular formula: C6H5D3N4O4. Mole weight: 203.17. | |
| Ropinirole-[d14] HCl (di-n-propyl-[d14]) | An isotope labelled of Ropinirole. Ropinirole is a dopamine agonist. It is used for the treatment of Parkinson's disease and restless legs syndrome. Synonyms: 4-[2-(Di-n-propylamino)ethyl]-2-indolinone HCl. Grade: 95% by HPLC; 99% atom D. CAS No. 1132746-05-4. Molecular formula: C16H11D14ClN2O. Mole weight: 310.92. | |
| Ropinirole-[d7] Hydrochloride | A deuterated Ropinirole impurity. Ropinirole is a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Synonyms: 4-[2-(Dipropyl-d7-amino)ethyl]-1,3-dihydro-2H-indol-2-one Hydrochloride; 4-[2-(Di-n-propyl-d7-amino)ethyl]-2(3H)-indolone Hydrochloride; SKF-101468A-d7. Grade: >95%. CAS No. 1261396-31-9. Molecular formula: C16H18D7ClN2O. Mole weight: 303.88. | |
| Rosiglitazone | Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Synonyms: BRL49653; BRL-49653; BRL 49653; HSDB 7555; HSDB-7555; HSDB7555; TDZ 01; TDZ-01; TDZ01; Rosiglitazone. trade name Avandia. Grade: >98%. CAS No. 122320-73-4. Molecular formula: C18H19N3O3S. Mole weight: 357.43. | |
| Rosiglitazone-[d3] | Rosiglitazone-[d3] is the labelled analogue of Rosiglitazone. Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Synonyms: Rosiglitazone D3; 5-[[4-[2-((Methyl-d3)-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione. Grade: 95% by HPLC; 95% atom D. CAS No. 1132641-22-5. Molecular formula: C18H16D3N3O3S. Mole weight: 360.45. | |
| Rosiglitazone maleate | Rosiglitazone exhibits insulin-sensitising activity 60- to 200-fold higher than that of troglitazone, englitazone, or piogliazone in rodent models of insulin ressitance. Uses: Hypoglycemic agents. Synonyms: Rosiglitazone Maleate; Avandia; Avandaryl; BRL-49653C; BRL49653C; BRL 49653C; BRL-49653-C. Grade: >98%. CAS No. 155141-29-0. Molecular formula: C18H19N3O3S.C4H4O4. Mole weight: 473.5. | |
| Rosuvastain Calcium | Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM. Uses: Anticholesteremic agents. Synonyms: ZD4522; ZD 4522; ZD-4522. Grade: >98%. CAS No. 147098-20-2. Molecular formula: C22H28FN3O6S.1/2Ca. Mole weight: 500.57. | |
| Rosuvastatin-[d6] Sodium Salt | One of the isotopic labelled form of Rosuvastatin sodium salt, which is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 7-[4-(4-Fluorophenyl)-6-(1-methylethyl-d6)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. CAS No. 2070009-41-3. Molecular formula: C22H21D6FN3NaO6S. Mole weight: 509.56. | |
| Rosuvastatin EP Impurity F | Rosuvastatin EP Impurity F is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Synonyms: Rosuvastatin Calcium EP Impurity F; tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; tert-Butyl [(4R,6S)-6-[(1E)-2-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]ethen-1-yl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 1,1-Dimethylethyl [(4R,6S)-6-[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-pyrimidin-5-yl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-; (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate; USP Rosuvastatin Related Compound C; Rosuvastatin Related Compound C; Rosuvastatin USP Related Compound C. Grade: ≥95%. CAS No. 289042-12-2. Molecular formula: C29H40FN3O6S. Mole weight: 577.72. | |
| Rosuvastatin Lactone-[d6] | A deuterated Rosuvastatin impurity. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: N-[4-(4-Fluorophenyl)-6-(1-methylethyl-d6)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide; Rosuvastatin-5S-lactone-d6. Grade: ≥90%. Molecular formula: C22H20D6FN3O5S. Mole weight: 469.56. | |
| (±)-Rotigotine | (±)-Rotigotine is a non-ergot dopamine agonist drug used to treat Parkinson's disease. Synonyms: 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-; 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol; (±)-N 0437; N 0437; Racemic N 0437; 6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol; 6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol. Grade: 95%. CAS No. 92206-54-7. Molecular formula: C19H25NOS. Mole weight: 315.47. | |
| Rotigotine-[d7] Hydrochloride | Rotigotine-[d7] Hydrochloride is the labelled hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50 values of 13 nM and 0.71 nM for D2 and D3 receptor respectively. Grade: > 95%. CAS No. 2070009-57-1. Molecular formula: C19H18NOSD7·HCl. Mole weight: 358.98. | |
| Rotundine | Rotundine (L-tetrahydropalmatine, L-THP) is an alkaloid found in several different plant species. It is a selective dopamine D1 receptor antagonist with IC50 of 166 nM. Uses: Antihypertensive agents. Synonyms: (13aS)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; O,O-Dimethyl-N-demethyl-cyclanoline; Gindarine; (-)-2,3,9,10-Tetramethoxyberbine; (-)-Corydalis B; (-)-S-Tetrahydropalmatine; (-)-Tetrahydropalmatine; (S)-Tetrahydropalmatine; Caseanine; Hyndarine; N-Demethyl-O,O'-dimethylcyclanoline; N-Demethyl-O,O'-dimethylsteponine. Grade: >98%. CAS No. 483-14-7. Molecular formula: C21H25NO4. Mole weight: 355.43. | |
| Roxithromycin-[d7] | A deuterated Roxithromycin. Roxithromycin is a bacterial protein synthesis inhibitor and a macrolide antibiotic. Synonyms: Rulid-d7; Roxid-d7; Surlid-d7; RU 965-d7; Overal-d7; Brilid-d7; Assoral-d7; Forilin-d7; ClaraMid-d7; RU 28965-d7; (9E)-9-[O-[(2-Methoxyethoxy-d7)methyl]oxime] Erythromycin. Grade: >98%. Molecular formula: C41H69D7N2O15. Mole weight: 844.09. | |
| Rufinamide-[15N,d2] | Rufinamide-[15N,d2] is the labelled analogue of rufinamide. Rufinamide is an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product. Synonyms: Rufinamide 15N D2; 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide-15N,d2. Grade: 95% by HPLC; 95% atom 15N. CAS No. 1795037-48-7. Molecular formula: C10H6D2F2N3[15N]O. Mole weight: 241.20. | |
| Ruxolitinib-[d4] | A deuterated ruxolitinib. Ruxolitinib is a janus-associated kinase inhibitor indicated to treat bone marrow cancer, specifically intermediate or high-risk myelofibrosis. Synonyms: Ruxolitinib-d4; (3R)-3-[(3,3,4,4-D4)cyclopentyl]-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile; (S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile-D4. Grade: >98%. CAS No. 1513883-31-2. Molecular formula: C17H14D4N6. Mole weight: 310.39. | |
| S-(+)-2-Amino-1-propanol-[3,3,3-d3] | S-(+)-2-Amino-1-propanol-[3,3,3-d3]. Synonyms: S-(+)-2-Amino-1-propanol-3,3,3-D3. CAS No. 352438-84-7. Molecular formula: C3H6D3NO. Mole weight: 78.13. | |
| (S)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol | (S)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: 2-Thiophenemethanol, α-[2-(methylamino)ethyl]-, (αS)-; 2-Thiophenemethanol, α-[2-(methylamino)ethyl]-, (S)-; (1S)-(-)-3-(Methylamino)-1-(thien-2-yl)propan-1-ol; (1S)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol; (S)-(-)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol; (S)-(-)-3-Methylamino-1-(2-thienyl)propan-1-ol; (S)-3-Methylamino-1-(2-thienyl)-1-propanol; N-Methyl-(S)-(-)-3-Hydroxy-3-(2-thiophen)propylamine; (αS)-α-[2-(Methylamino)ethyl]-2-thiophenemethanol; Duloxetine EP Impurity B. Grade: 98.0%. CAS No. 116539-55-0. Molecular formula: C8H13NOS. Mole weight: 171.26. | |
| (S)-4-Benzyl-2-oxazolidinone | An impurity of Zolmitriptan, which is a serotonin 5-HT1 B and D receptor agonist used for the treatment of migraine. Synonyms: (4S)-4-(Phenylmethyl)-2-oxazolidinone; (-)-4-Benzyl-2-oxazolidinone; (4S)-4-(Phenylmethyl)-1,3-oxazolidin-2-one; (4S)-Benzyloxazolidin-2-one; 2-Oxazolidinone, 4-(phenylmethyl)-, (4S)-; 2-Oxazolidinone, 4-(phenylmethyl)-, (S)-; (4S)-(-)-4-(Phenylmethyl)-1,3-oxazolidin-2-one; (4S)-4-Benzyloxazolidin-2-one; (S)-(-)-4-Benzyl-1,3-oxazolidin-2-one; (S)-(-)-4-Benzyl-2-oxazolidinone; (S)-4-Benzyloxazolidin-2-one; (S)-4-Benzyloxy-2-azolidinone; (S)-4-Phenylmethyl-2-oxazolidinone; 4-(S)-Benzyl-2-oxazolidinone; 4S-(Phenylmethyl)oxazolidin-2-one; 4S-Benzyloxazolidin-2-one. Grade: ≥95%. CAS No. 90719-32-7. Molecular formula: C10H11NO2. Mole weight: 177.20. | |
| Saccharin-[13C6] | Saccharin-[13C6] is the labelled analogue of saccharin. Saccharin is an artificial sweetener with effectively no food energy that is about 300-400 times as sweet as sucrose but has a bitter or metallic aftertaste, especially at high concentrations. It is used to sweeten products such as drinks, candies, cookies, medicines, and toothpaste. Synonyms: Saccharin-13C6; 1,2-(Benzisothiazol-13C6)-3(2H)-one 1,1-Dioxide; 1,2-Dihydro-2-ketobenzisosulfonazole-13C6. Grade: 95% by HPLC; 95% atom 13C. CAS No. 1286479-01-3. Molecular formula: C[13C]6H5NO3S. Mole weight: 189.14. | |
| Saccharin-[d4] | Saccharin-[d4]. Uses: Labelled saccharin (s080800). it is a non-nutritive sweetener; pharmaceutic aid (flavor). saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria fo. Synonyms: Saccharin D4; (4,5,6,7-2H4)-1,2-Benzothiazol-3(2H)-one 1,1-dioxide. Grade: 95% atom D. CAS No. 1189466-17-8. Molecular formula: C7HD4NO3S. Mole weight: 187.21. | |
| Sacituzumab govitecan | Sacituzumab govitecan is an antibody-drug conjugate with an SN-38 payload targeting trophoblast cell-surface antigen 2, an epithelial antigen expressed in breast cancer. Synonyms: IMMU-132; IMMU 132; IMMU132. CAS No. 1491917-83-9. | |
| Sacubitril-[d4] | An isotope labelled AHU377, a methyl ester prodrug form of the neprilysin inhibitor LBQ657. Synonyms: AHU377-d4; (alphaR,gammaS)-gamma-[(3-carboxy-1-oxopropyl-2,2,3,3-d4)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoicacid,alpha-ethylester. Grade: ≥99% atom D. CAS No. 1884269-07-1. Molecular formula: C24H25D4NO5. Mole weight: 415.5. | |
| S-Adenosyl-L-methionine-[d3] | S-Adenosyl-L-Methionine-[d3] is a labelled S-Adenosyl-L-Methionine. S-Adenosyl-L-Methionine plays important roles in the liver such as a precursor cysteine, a methylating agent, an anti-inflammatory agent. Synonyms: (2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate-d3; S-adenosylmethionine-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 68684-40-2. Molecular formula: C15H19D3N6O5S. Mole weight: 401.46. | |
| SAFFLOWER YELLOW | Extract from Carthamin, widely used for the treatment of acute ischemic stroke by acting directly on BV2 microglia. Uses: Used for the treatment of acute ischemic stroke. Synonyms: Carthamine; Natural Red 26; Liofresh Red CR; Safflower red; (2R,6Z)-6-({(3Z,5S)-2,5-Dihydroxy-3-[(2E)-1-hydroxy-3-(4-hydroxyphenyl)-2-propen-1-ylidene]-4,6-dioxo-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-1-cyclohexen-1-yl} methylene)-2,5-dihydroxy-4-[(2E)-3-(4-hydr. Grade: ≥95%. CAS No. 36338-96-2. Molecular formula: C43H42O22. Mole weight: 910.78. | |
| Safinamide-[d4] | Safinamide-[d4] is the labelled analogue of safinamide. Safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: Safinamide D4. Grade: 95% by HPLC; 95% atom D. CAS No. 1147299-63-5. Molecular formula: C17H15D4FN2O2. Mole weight: 306.37. | |
| Salbutamol-[d9] | A deuterated salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Salbutamol-tert-butyl-d9; rac Albuterol-d9; [2H9]-Salbutamol; α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol-d9. Grade: 97% by CP. CAS No. 1173021-73-2. Molecular formula: C13H12D9NO3. Mole weight: 248.37. | |
| Salicylic acid | Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. It is widely used in organic synthesis and functions as a plant hormone and is known for its ability to ease aches and pains and reduce fevers. It is derived from the metabolism of salicin. It and its derivatives are used as constituents of some rubefacient products. In cosmetics, it has the effect of oil control, exfoliation, removing pimples, narrowing pores, and lightening marks. Uses: Anti-infective agents; antifungal agents; keratolytic agents. Synonyms: Lamivudine Impurity C; 2-Carboxyphenol; 2-Hydroxybenzenecarboxylic acid; Advanced Pain Relief Callus Removers; Advanced Pain Relief Corn Removers; Clear away Wart Remover; Compound W; Dr.Scholl's Callus Removers; Dr. Scholl's Corn Removers; Dr. Scholl's Wart Remover Kit; Duofil Wart Remover; Duoplant; FM 110602; Freezone; Ionil; Ionil Plus; K 537; K 557; NSC 180; o-Carboxyphenol; o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Psoriacid-S-Stift; Retarder W; Rutranex; Salicylic acid; Salicylic acid collodion; Salicylic Acid Soap; Saligel; Salonil; Salvona Nanosal; Stri-Dex; Trans-Ver-Sal; Verrugon; Lamivudine EP Impurity C. Grade: >95%. CAS No. 69-72-7. Molecular formula: C7H6O3. Mole weight: 138.12. | |
| Salicylic Acid-[13C6] | Salicylic Acid-[13C6] is a labelled analogue of Salicylic acid. Salicylic acid is a natural product extracted from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. Salicylic acid is widely used in organic synthesis and functions as a plant hormone and is known for its ability to ease aches and pains and reduce fevers. Uses: Labelled acetylsalicylic acid impurity b. Synonyms: Salicylic Acid 13C6; 2-Hydroxy(13C6)benzoic acid; [U-ring-13C6]-Hydroxybenzoic acid. Grade: 95% atom 13C. CAS No. 1189678-81-6. Molecular formula: C[13C]6H6O3. Mole weight: 144.08. | |
| Salicylic Acid-[d4] | An isotope labelled form of Salicylic Acid. Salicylic Acid is an organic buliding block that can be used in organic synthesis. Synonyms: 2-Hydroxybenzoic Acid-d4; 2-Carboxyphenol-d4; 2-Hydroxybenzenecarboxylic Acid-d4; 2-Hydroxybenzoic Acid-d4; o-Carboxyphenol-d4; o-Hydroxybenzoic Acid-d4; Rutranex-d4; Saligel-d4; Salonil-d4; Salvona Nanosal-d4; Stri-Dex-d4; Trans-Ver-Sal-d4; Verrugon-d4. Grade: 98% by HPLC; 99% atom D. CAS No. 78646-17-0. Molecular formula: C7H2D4O3. Mole weight: 142.15. | |
| Salidroside | Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside has whitening and anti-radiation effects, thus can be used in cosmetics material. Uses: Antidepressant and anxiolytic. Synonyms: Rhodioloside; 2-(4-Hydroxyphenyl)ethyl-b-D-glucopyranoside; Tyrosol glucoside. Grade: >98%. CAS No. 10338-51-9. Molecular formula: C14H20O7. Mole weight: 300.30. | |
| S-Allyl-[d5]-L-cysteine | S-Allyl-[d5]-L-cysteine is a labelled S-Allyl-L-cysteine. S-Allyl-L-cysteine is a derivative of cysteine with the potential of lowering cholesterol level. Synonyms: S-Allyl-d5-L-cysteine. Grade: 95% by HPLC; 98% atom D. CAS No. 1217444-21-7. Molecular formula: C6H6D5NO2S. Mole weight: 166.25. | |
| Salmeterol-[d3] | A deuterated salmeterol. Salmeterol is a β2-Adrenergic agonist used for relief and control of asthma symptoms. Synonyms: 4-Hydroxy-alpha1[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol-d3; GR-33343X-d3. Grade: 98%; 99% atom D. CAS No. 497063-94-2. Molecular formula: C25H34D3NO4. Mole weight: 418.58. | |
| (±)-Salmeterol-d3 Xifoate (3-hydroxymethyl-d2; a-d1) | One of the isotopic labelled form of (±)-Salmeterol Xifoate, which is a β2-Adrenergic agonist and could be used as a bronchodilator. Synonyms: (±)-Salmeterol 1-Hydroxy-2-phthoate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C25H34D3NO4. C11H8O3. Mole weight: 606.77. | |
| (±)-Salsolinol hydrochloride | (±)-Salsolinol is a metabolite of ethanol produced by the condensation of dopamine with acetaldehyde in the brain. It is thought to contribute to some aspects of alcohol's addictive properties in part through its ability to stimulate dopamineric neurons in the posterior ventral tegmental area of the brain. Synonyms: (+-)-Salsolinol hydrochloride; Salsolinol hydrochloride, (+/-)-; 1-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol chloride. Grade: ≥99%. CAS No. 79923-51-6. Molecular formula: C10H13NO2·HCl. Mole weight: 215.7. | |
| Sapropterin-[d3] | A deuterated Sapropterin. Sapropterin is a cofactor for phenylalanine hydroxylase. Synonyms: (R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one-D3. Grade: >95%. Molecular formula: C9H12D3N5O3. Mole weight: 244.27. | |
| Saquinavir-[d6] | A deuterated squinavir. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases. Synonyms: (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide-d6; Fortovase-d6; Invirase-d6; Ro 31-8959-d6. Grade: >95%. Molecular formula: C38H44D6N6O5. Mole weight: 676.90. | |
| Saquinavir-[d9] | A deuterated squinavir. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases. Synonyms: (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide-d9; Fortovase-d9; Invirase-d9; Ro 31-8959-d9. Grade: >98%. CAS No. 1356355-11-7. Molecular formula: C38H41D9N6O5. Mole weight: 679.91. | |
| Sarafloxacin-[d8] hydrochloride hydrate | Sarafloxacin-[d8] hydrochloride hydrate is a labelled analogue of Sarafloxacin. Sarafloxacin is a topoisomerase II ligase inhibitor used as a quinolone antibiotic drug. Synonyms: Sarafloxacin-D8 hydrochloride hydrate; Difloxacino-d8 hydrochloride hydrate; Difloxacinum-d8 hydrochloride hydrate; Sarafloxacino-d8 hydrochloride hydrate; Sarafloxacinum-d8 hydrochloride hydrate; 6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazine-D8-1-yl-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C20H9D8F2N3O3.HCl.H2O. Mole weight: 447.87. | |
| Sarcosine-[13C3,15N] HCl | Sarcosine-[13C3,15N] HCl is a labelled salt of Sarcosine. Sarcosine is an intermediate of choline metabolism. Synonyms: N-methylglycine-13C3,15N HCl. Grade: 98% by HPLC; 99% atom 13C, 98% atom 15N. Molecular formula: [13C]3H8Cl[15N]O2. Mole weight: 129.53. | |
| Sarcosine-[d3] | Sarcosine-[d3] is a labelled compound Sarcosine. Sarcosine is an endogenous GlyT1 inhibitor. Sarcosine displays antipsychotic activity and has the potential to treat schizophrenia. Sarcosine has been shown to potentiate the action of glycine on the NMDA glycine binding site. Synonyms: N-Methyl-d3-glycine; [2H3]Sarcosine. Grade: 99% atom D. CAS No. 118685-91-9. Molecular formula: C3H4D3NO2. Mole weight: 92.11. | |
| Sarcosine-[d3] Hydrochloride | Sarcosine-[d3] Hydrochloride is a labelled sarcosine hydrochloride. Sarcosine is a byproduct in the synthesis of glycine. Sarcosine is naturally found in the muscles and some other tissues. Synonyms: N-Methyl-d3-glycine HCl; N-Methylaminoacetic Acid-d3 HCl; H-Sar-OH-d3 HCl; N-Me-Gly-OH-d3 HCl; 2-(trideuteriomethylamino)acetic acid hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 347840-04-4. Molecular formula: C3H5D3ClNO2. Mole weight: 128.57. | |
| Sarpogrelate-[d3] HCl | Sarpogrelate-[d3] HCl is a deuterated Sarpogrelate HCl. Sarpogrelate is a drug which acts as an antagonist at the 5HT2A and 5-HT2B receptors. Synonyms: Sarpogrelate-d3 HCl; Sarpogrelate-D3 hydrochloride. Grade: > 95%. Molecular formula: C24H29D3ClNO6. Mole weight: 468.99. | |
| Saxagliptin-[13C3] | Saxagliptin-[13C3] is the labelled analogue of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: Saxagliptin-13C3; (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile-13C3. Grade: 95% by HPLC; 95% atom 13C. CAS No. 1246812-44-1. Molecular formula: C15[13C]3H25N3O2. Mole weight: 318.39. | |
| Saxagliptin-[13C,d2] TFA Salt | Saxagliptin-[13C,d2] TFA Salt is the labelled analogue of Saxagliptin. Saxagliptin is an anti-diabetic drug of the dipeptidyl peptidase-4 inhibitor class. Synonyms: Saxagliptin-13C,d2 TFA Salt. Grade: 95% by HPLC; 98% atom D; 98% atom 13C. Molecular formula: C17[13C]H23D2N3O2.C2HF3O2. Mole weight: 432.44. | |
| (-)-(S)-B-973B | (-)-(S)-B-973B is an allosteric agonist and positive allosteric modulator (ago-PAM) of α7 nAChR. Synonyms: (S)-B-973B. Grade: 98% by HPLC. CAS No. 2244989-34-0. Molecular formula: C24H26F2N6O. Mole weight: 452.5. | |
| S-benzyl-DL-Cysteine-[1-13C] | S-benzyl-DL-Cysteine-[1-13C] is a labelled S-benzyl-DL-Cysteine, which is a derivative of cysteine. Grade: 98% by HPLC; 99% atom 13C. CAS No. 77284-35-6. Molecular formula: C9[13C]H13NO2S. Mole weight: 212.27. | |
| S-Benzyl-DL-cysteine-[2,3,3-d3] | S-Benzyl-DL-cysteine-[2,3,3-d3] is a labelled S-Benzylcysteine, which is a derivative of cysteine. Grade: 95% by HPLC; 98% atom D. CAS No. 51494-04-3. Molecular formula: C10H10D3NO2S. Mole weight: 214.3. | |
| S-benzyl-L-Cysteine-[3-13C] | S-benzyl-L-Cysteine-[3-13C] is a labelled S-benzyl-L-Cysteine, which is a derivative of cysteine. Grade: 98% by HPLC; 99% atom 13C. CAS No. 79761-09-4. Molecular formula: C4[13C]H9NO4. Mole weight: 212.27. | |
| S-(+)-Bicalutamide-[d4] | S-(+)-Bicalutamide-[d4] is a labelled (S)-enantiomer of Bicalutamide. Bicalutamide is an antiandrogen drug commonly used for the treatment of prostate cancer. Synonyms: (2S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-d4)sulfonyl]-2-hydroxy-2-methylpropanamide; (S)-Casodex-d4. Grade: > 95%. CAS No. 1217769-79-3. Molecular formula: C18H10F4N2O4SD4. Mole weight: 434.41. | |
| SCA-[13C,15N2] hydrochloride | SCA-HCl-13C,15N2 is a labelled salt of Semicarbazide. Synonyms: SCA-HCl-13C,15N2; Semicarbazide-13C,15N2 Hydrochloride; Hydrazinecarboxamide-13C,15N2 Monohydrochloride; Aminourea-13C,15N2 Hydrochloride; Semicarbazide-13C,15N2 Chloride; SEM-13C,15N2. Grade: 95% by HPLC; 98% atom 13C; 98% atom 15N. CAS No. 1173020-16-0. Molecular formula: [13C]H5N[15N]2O.HCl. Mole weight: 114.51. | |
| S-(-)-Carbidopa-[d3] | S-(-)-Carbidopa-[d3] is the labelled analogue of Carbidopa. Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor. It is commonly used in combination with L-DOPA for the treatment of Parkinsonism. Synonyms: S-(-)-Carbidopa-D3; Carbidopa-d3; Lodosyn-d3; N-Aminomethyldopa-d3; (S)-carbidopa-d3; alpha-Methyldopahydrazine-d3; L-alpha-Methyldopahydrazine-d3; (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid-d3. Grade: >98% by HPLC; >98% atom D. CAS No. 1276732-89-8. Molecular formula: C10H11D3N2O4. Mole weight: 229.25. | |
| (+)-(S)-Citalopram-d4 Oxalate | (+)-(S)-Citalopram-d4 Oxalate is the labelled analogue of (S)-Citalopram Oxalate, which is an inhibitor of serotonin (5-HT) uptake, and an antidepressant agent. Synonyms: (1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile-d4 Ethanedioate; Escitalopram-d4 Oxalate; (S)-(+)-Citalopram-d4 Oxalate; Cipralex. Grade: 98% HPLC. Molecular formula: C20H17FN2OD4·C2H2O4. Mole weight: 418.47. | |
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