BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Atropine sulfate hydrate (2:1:1) | Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery. Uses: Adjuvants, anesthesia. Alternative Names: Atropine sulfate monohydrate; Atropini sulfas; Isopto Atropine; Atropinum sulphuricum; Atropine sulfate. Grades: >98%. CAS No. 5908-99-6. Molecular formula: 2C17H23NO3.H2O4S.H2O. Mole weight: 694.837. |  |
| Attapulgite | Attapulgite is widely used as an adsorbent for solid dosage forms. Alternative Names: Actapulgite; Attaclay; Attacote; Attagel; attapulgus; palygorscite; palygorskite; Pharmsorb Regular. Grades: 95%. CAS No. 12174-11-7. Molecular formula: Al.Fe.4H2O.HO.Mg.Si2O5. Mole weight: 332.37. | |
| Atto 425-NHS ester | Atto 425-NHS Ester is a fluorescent label useful in monitoring three-component protein-protein interactions in vitro and in living cells. Furthermore, it is utilized to identify and measure the concentration of specific proteins in biological specimens. Alternative Names: Atto 425-N-hydroxysuccinimide ester; ATTO 425-3; Atto 425-N-hydroxysuccinimide ester. CAS No. 892156-28-4. Molecular formula: C26H30N2O8. Mole weight: 498.53. | |
| Atto 590 nhs ester | ATTO 590 is a novel fluorescent label belonging to the class of Rhodamine dyes. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins. The ATTO dyes are a series of fluorescent dyes that provide all the crucial properties required for modern fluorescent technologies, such as fluorescence microscopy, flow-cytometry, fluorescence in situ hybridization (FISH), receptor binding assays or enzyme assays. The dye is highly suitable for single-molecule detection applications and high-resolution microscopy. The NHS-esters are used in common conjugation protocols.ATTO 590 is a novel fluorescent label belonging to the class of Rhodamine dyes, which has an absorption maximum of 594 nm and an emission maximum of 624 nm. ATTO 590-N-hydroxysuccinimide (NHS) is membrane permeable. Uses: Molar absorption 120,000 1/m cm, abs: 593 nm, em: 620 nm, qy=0.93, tfl 4.0 ns (unpublished data)atto 590 nhs ester may be suitable for use in site-specific labeling of human embryonic kidney (hek293t) cell lysates for western blotting, fluorescence, and widefield microscopy studies. Alternative Names: 2-(6,20-diethyl-7,7,9,17,19,19-hexamethyl-2-oxa-20-aza-6-azoniapentacyclo[12.8.0.03,12.05,10.016,21; docosa-1(14),3,5,8,10,12,15,17,21-nonaen-13-yl)-4-(2,5-dioxopyrrolidin-1-yl)oxycarbonylbenzoic acid;perchlorate; 6-(2-Carboxy-5-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}phenyl)-1,11-diethyl-2,2,4,8,10,10-hex | |
| ATX-100 | ATX-100 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA. Alternative Names: ATX100; ATX 100; 4,4'-[[[[3-(dimethylamino)propyl]thio]carbonyl]imino]bis-butanoic acid, 1,1'-bis(1-heptyloctyl) ester. CAS No. 2230647-37-5. Molecular formula: C44H86N2O5S. Mole weight: 755.23. | |
| Auranofin | Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Uses: Auranofin inhibits various leukocyte activation pathways at multiple sites. Alternative Names: SKF-39162; SKF-D-39162; SKF 39162; SKF D 39162; SKFD-39162; SKFD39162; Ridaura; NSC 321521, Ridauragold thiol; Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-; [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold; Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate; Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-; β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex; [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold; Aktil; Crisinor; Crisofin Gold Salt; Ridauran; SKF 39162D. Grades: ≥98%. CAS No. 34031-32-8. Molecular formula: C20H34AuO9PS. Mole weight: 678.49. | |
| Aurate(1-),tetrachloro-, hydrogen, hydrate, (SP-4-1)- (9CI) | Aurate(1-),tetrachloro-, hydrogen, hydrate, (SP-4-1)- (9CI). Alternative Names: GOLD TRICHLORIDE ACID; GOLD TRICHLORIDE ACID HYDRATE; GOLD CHLORIDE HYDRATE; GOLD CHLORIDE, YELLOW; HYDROGEN TETRACHLOROAURATE; HYDROGEN TETRACHLOROAURATE(+3)N-HYDRATE. Grades: ≥99%. CAS No. 27988-77-8. Molecular formula: AuCl4. x H2 O. H. Mole weight: 357.8. | |
| Aurintricarboxylic acid ammonium salt | Aurintricarboxylic acid ammonium salt (CAS# 569-58-4) is used in preparation method of amorphous silica-alumina catalyst for use in reaction of methanol and ammonia to produce monomethylamine, dimethylamine and trimethylamine. Alternative Names: azane;5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid. CAS No. 569-58-4. Molecular formula: C22H23N3O9. Mole weight: 473.43. | |
| Auxin | Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone. Uses: Plant growth regulators. Alternative Names: Auxin; IAA; 3-Indoleacetic acid. Grades: ≥ 98 % (HPLC). CAS No. 87-51-4. Molecular formula: C10H9NO2. Mole weight: 175.18. | |
| Avacincaptad pegol | Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA). CAS No. 1613641-69-2. | |
| Avacincaptad pegol sodium | Avacincaptad pegol (ARC1905) is is an anti-C5 RNA aptamer that inhibits the cleavage of complement factor 5 (C5) into C5a and C5b. Avacincaptad pegol is being used for the study of age-related macular degeneration (AMD). Alternative Names: ARC1905; ARC 1905; ARC-1905. CAS No. 1491144-00-3. Mole weight: 52390.8. | |
| Avapritinib | BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Alternative Names: (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297. CAS No. 1703793-34-3. Molecular formula: C26H27FN10. Mole weight: 498.56. | |
| Avarol | Avarol. CAS No. 55303-98-5. Molecular formula: C21H30O2. Mole weight: 314.5. | |
| Avasimibe | Avasimibe inhibits Lipoprotein(a) accumulation in the culture media of primary monkey hepatocyte in a dose-dependent manner with 11.9% -31.3% inhibition, the change is mainly associated with decreased ApoA. Uses: Cytochrome p-450 cyp3a inducers. Alternative Names: CI-1011; CI 1011; CI1011; ((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl este; Sulfamic acid, N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl esterr. Grades: >98%. CAS No. 166518-60-1. Molecular formula: C29H43NO4S. Mole weight: 501.72. | |
| Avatrombopag | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Alternative Names: AKR-501; AKR 501; AKR501; YM477; YM-477; YM 477; E5501; AS 1670542; AS1670542; AS-1670542. Grades: 98%. CAS No. 570406-98-3. Molecular formula: C29H34Cl2N6O3S2. Mole weight: 649.65. | |
| Avatrombopag maleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. CAS No. 677007-74-8. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. | |
| AVE 0118 hydrochloride | AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Alternative Names: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grades: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03. | |
| AVE 0991 | AVE 0991 is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Alternative Names: 1-ethyl-3-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylurea5-formyl-4-methoxy-2-phenyl-1-((4-(2-ethyl-aminocarbonylsulfonamido-5-isobutyl-3-thienyl)phenyl)methyl)imidiazoleAVE 0991; AVE-0991; AVE0991. CAS No. 304462-19-9. Molecular formula: C29H32N4O5S2. Mole weight: 580.72. | |
| AVE-8063 | AVE-8063 is an antimitotic agent or microtubule inhibitor with potential anticancer activity. Alternative Names: AVE8063; AVE 8063; (Z)-1-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl) aniline. Grades: >98%. CAS No. 162705-07-9. Molecular formula: C18H21NO4. Mole weight: 315.37. | |
| Avibactam | Avibactam is a novel investigational non-beta-lactam beta-lactamase inhibitor that is being developed for possible use in combination with ceftaroline in the U.S. Avibactam does not have any intrinsic antibacterial activity in its own right, but appears to be capable of inhibiting beta-lactamase enzymes that belong to molecular classes A and C.Avibactam is useful for Antibiotics. Uses: Beta-lactamase inhibitors. Alternative Names: Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester; Avibactam free acid; [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate. Grades: >98%. CAS No. 1192500-31-4. Molecular formula: C7H11N3O6S. Mole weight: 265.24. | |
| Avibactam Impurity 6 | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Alternative Names: (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (1R,2S,5R)-7-Oxo-6-(phenylmethoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. Grades: >95%. CAS No. 1192651-49-2. Molecular formula: C14H17N3O3. Mole weight: 275.31. | |
| Avibactam Impurity 9 | Avibactam Impurity 9 is an impurity of Avibactam. Alternative Names: Avibactam Intermediate; (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate; (2S,5R)-Ethyl 5-((benzyloxy)amino)piperidine-2-carboxylate Oxalate. Grades: > 95%. CAS No. 1416134-48-9. Molecular formula: C17H24N2O7. Mole weight: 377.39. | |
| Avibactam Sodium, (+)- | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Alternative Names: (2R,5S)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo(3.2.1)octane-2-carboxamide monosodium salt. Grades: ≥95%. CAS No. 1383814-68-3. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. | |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Alternative Names: sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium. CAS No. 1192491-61-4. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. | |
| Avidin | Avidin. Grades: 95%. CAS No. 1405-69-2. Molecular formula: C4H8O2. Mole weight: 88.11. | |
| Avobenzone | Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. Alternative Names: Avobenzonum; Parsol 1789; Parsol1789; Parsol-1789; HSDB 7423; HSDB-7423; HSDB7423; 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-; 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione; 1-(4'-tert-Butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione; 3-(4-Methoxyphenyl)-1-(4-tert-butylphenyl)-1,3-propanedione; 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane; 4-Methoxy-4'-tert-butyldibenzoylmethane; 4-tert-Butyl-4'-methoxydibenzoylmethane; Butylmethoxydibenzoylmethane; Escalol 517; Eusolex 9020; Milestab 1789; NeoHeliopan 357; Parsol 1789; Parsol A; Parsol RTM 1789; Photoplex; Solarom BMBM; Uvinul BMBM. Grades: >98%. CAS No. 70356-09-1. Molecular formula: C20H22O3. Mole weight: 310.39. | |
| Axitinib Impurity 1 | Axitinib Impurity 1 is an impurity of Axitinib, a drug primarily used in the treatment of advanced renal cell carcinoma and metastatic thyroid cancer. Alternative Names: Axitinib Impurity c. Grades: > 95%. CAS No. 885126-40-9. Molecular formula: C22H18N4OS. Mole weight: 386.48. | |
| Axitinib Impurity 2 | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Alternative Names: 2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide). Grades: > 95%. CAS No. 1428728-83-9. Molecular formula: C44H36N8O2S2. Mole weight: 772.96. | |
| Axitinib sulfone | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Alternative Names: Sulfonyl axitinib; (E)-N-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylsulfonyl)benzamide; N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide. Grades: ≥95%. CAS No. 1348536-59-3. Molecular formula: C22H18N4O3S. Mole weight: 418.47. | |
| Axitinib sulfoxide | A major metabolite of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide; Axitinib Impurity A. Grades: > 95%. CAS No. 1347304-18-0. Molecular formula: C22H18N4O2S. Mole weight: 402.48. | |
| AZ0108 | AZ0108 is an orally bioavailable, PARP1,2,6 inhibitor that causes a multi-polar spindle phenotype at double digit nM concentrations. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. Alternative Names: (S)-4-((3-(3-(1,1-difluoroethyl)-6-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)phenyl)difluoromethyl)phthalazin-1(2H)-one; AZ0108; AZ-0108; AZ 0108. Grades: >98%. CAS No. 1825345-52-5. Molecular formula: C24H20F4N6O2. Mole weight: 500.45. | |
| AZ505 | AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 μM) with potential anticancer activity. Alternative Names: AZ 505; AZ-505; N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)propanamide. Grades: 98%. CAS No. 1035227-43-0. Molecular formula: C29H38Cl2N4O4. Mole weight: 577.54. | |
| AZ5104 | AZ5104 is a potent EGFR inhibitor and a derivative of AZD 9291. AZ5104 exhibits reduced selectivity against wild-type EGFR but five-fold potentcy compared to AZD 9291. Alternative Names: AZ-5104; AZ 5104; N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide. CAS No. 1421373-98-9. Molecular formula: C27H31N7O2. Mole weight: 485.592. | |
| AZ7550 Mesylate | AZ7550 Mesylate, an active metabolite of AZD9291, inhibits the activity of IGF1R with an IC50 of 1.6 μM. Alternative Names: AZ7550 trimesylate salt; N-(4-Methoxy-5-{[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}phenyl)acrylamide methanesulfonate (1:3); 2-Propenamide, N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-, methanesulfonate (1:3). Grades: ≥98%. CAS No. 2319837-99-3. Molecular formula: C30H43N7O11S3. Mole weight: 773.90. | |
| AZA | ~4-fold increase in efficiency with OSKM and promotes full reprogramming. Uses: Reprogramming. Alternative Names: 3'-Azido-2',3'-dideoxyadenosine; 66323-44-2; 3'-Azido-ddA; 3'-AzddAdo; [(2S,3S,5R)-5-(6-aminopurin-9-yl)-3-azidooxolan-2-yl]methanol; 3'-N3-ddA; [(2S,3S,5R)-5-(6-aminopurin-9-yl)-3-azido-tetrahydrofuran-2-yl]methanol; HG1022; 3'-Azido-2'-deoxyadenosine; CHEMBL590121; SCHEMBL18640424; DTXSID10216534; XDRZJDXXQHFAAE-RRKCRQDMSA-N; MFCD01630963; AKOS037644233; ((2S,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-azidotetrahydrofuran-2-yl)methanol; AS-49374; CS-0199753; A835421; 9-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)adenine; 9-(3'-Azido-2',3'-dideoxy-.beta.-D-erythro-pentofuranosyl)adenine; 9-(3'-Azido-2',3'-dideoxy-beta-D-erythro-pentofuranosyl)adenine; [(2S,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-azidooxolan-2-yl]methanol; 9H-purin-6-amine, 9-(3-azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-. Grades: ≥ 97%. CAS No. 66323-44-2. Molecular formula: C10H12N8O2. Mole weight: 276.26. | |
| Azabicyclo[2,2,1]hept-5-en-3-one | Azabicyclo[2,2,1]hept-5-en-3-one. CAS No. 49805-30-0. | |
| Azadirachtin | Azadirachtin is a tetranortriterpinoid isolated from the seeds of the neem tree. It is highly active insect feeding deterrent and growth regulator. It can be used experimentally as an insect control agent. Uses: Insecticides. Alternative Names: Nimbicidine; Nimurin; Ornazin. Grades: 95%. CAS No. 11141-17-6. Molecular formula: C35H44O16. Mole weight: 720.72. | |
| Azadirachtin B | Azadirachtin B is a drug analog of azadirachtin which was investigated in agrochemical studies of bioregulators for the antifeedant mode of action of parent molecule against Lepidoptera and locusts. Alternative Names: Deacetylazadirachtinol; Azadirachtinol deacetyl; 3-tigloyl-azadirachtol; 3-Tigloylazadirachtol. Grades: 98%. CAS No. 106500-25-8. Molecular formula: C33H42O14. Mole weight: 662.68. | |
| Azaleatin | Azaleatin is an O-methylated flavonol, a type of flavonoid. It was first isolated from the flowers of Rhododendron mucronatum in 1956 and has since been recorded in forty-four other Rhododendron species, in Plumbago capensis, in Ceratostigma willmottiana and in Carya pecan. It has been also been found in the leaves of Eucryphia. It is the 3-O-α-L-rhamnoside of azaleatin. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4',7-Tetrahydroxy-5-methoxyflavone; 5-O-Methyl quercetin; Quercetin 5-Methyl Ether; 2-(3,4-Dihydroxycyclohexa-2,4-dien-1-yl)-3,7-dihydroxy-5-methoxy-4H-chromen-4-one. Grades: ≥95%. CAS No. 529-51-1. Molecular formula: C16H12O7. Mole weight: 316.26. | |
| Azamethonium bromide | Azamethonium bromide. Grades: 95%. CAS No. 306-53-6. Molecular formula: C13H33N3Br2. Mole weight: 391.22922. | |
| Azanidazole | Azanidazole. Alternative Names: Azanidazole. Grades: 95%. CAS No. 62973-76-6. Molecular formula: C10H10N6O2. Mole weight: 246.229. | |
| Azaperone | Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. Alternative Names: NSC 170976; NSC170976; NSC-170976. Grades: >98%. CAS No. 1649-18-9. Molecular formula: C19H22FN3O. Mole weight: 327.4. | |
| AZD1152-HQPA | Barasertib is a potent and highly selective inhibitor of AURKB with IC50 of 0.37 nM, acting via preventing the transfer of the phosphate group from the ATP molecule to AURKB substrates. The present study demonstrated for the first time, that AURKB inhibition interferes with early regeneration of SGs. Barasertib has been demonstrated that it is 3,700-fold greater selectivity than Aurora A. Alternative Names: INH 34; AZD1152-HQPA; AZD2811. Grades: ≥98%. CAS No. 722544-51-6. Molecular formula: C26H30FN7O3. Mole weight: 507.56. | |
| AZD2716 | AZD2716 is a potent sPLA2 inhibitor (IC50 = 10, 40, and 400 nM for sPLA2-IIa, -V, and -X, respectively). When incubated with HepG2 cells, AZD2716 effectively inhibited sPLA2 activity (IC50 value of <14 nM) and suppressed production of sPLA2-IIa (IC50 = 176 nM). Alternative Names: AZD2716; AZD-2716; AZD 2716. (2R)-3-[3-(5-benzyl-2-carbamoylphenyl)phenyl]-2-methylpropanoic acid. Grades: 99%. CAS No. 1845753-81-2. Molecular formula: C24H23NO3. Mole weight: 373.44. | |
| AZD3839 | AZD3839, also called CHEMBL2177913, as a potent BACE1 inhibitor it is a clinical candidate for the treatment of Alzheimer's disease. Studies indicate that the inhibition of BACE1 impedes the production of Aβ peptide. Alternative Names: AZD3839; AZD-3839; AZD 3839. (3S)-3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine; CHEMBL2177913; I8ID590133; UNII-I8ID590133; I8ID590133; SCHEMBL1358337; BDBM50398264; (1S)-1-(2-(Difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine; 1227163-84-9; 1H-Isoindol-3-amine, 1-(2-(difluoromethyl)-4-pyridinyl)-4-fluoro-1-(3-(5-pyrimidinyl)phenyl)-, (1S)-. CAS No. 1227163-84-9. Molecular formula: C24H16F3N5. Mole weight: 431.41. | |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Alternative Names: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. Grades: >98%. CAS No. 1448671-31-5. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. | |
| AZD-4547 | AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. Alternative Names: AZD-4547; AZD 4547; AZD4547; N-{3-[2-(3,5-Dimethoxyphenyl)ethyl]-1h-Pyrazol-5-Yl}-4-[(3r,5s)-3,5-Dimethylpiperazin-1-Yl]benzamide. Grades: 98%. CAS No. 1035270-39-3. Molecular formula: C26H33N5O3. Mole weight: 463.582. | |
| AZD-4694 | AZD-4694 is a bio-active chemical compound and is used as a diagnostic imaging agent. It was developed by AstraZeneca. Alternative Names: AZD 4694; AZD-4694; AZD4694; NAV4694; NAV 4694; NAV-4694; Flutafuranol; 2-(2-Fluoro-6-methylaminopyridin-3-yl)benzofuran-5-ol. Grades: >98%. CAS No. 1054629-49-0. Molecular formula: C14H11FN2O2. Mole weight: 258.25. | |
| AZD5305 | AZD5305 is a potent, selective and orally active inhibitor of PARP1 with IC50 of 3 nM in wild-type A549 lung cancer cells. AZD5305 is under clinical trials for advanced solid tumor treatment. Alternative Names: Saruparib; AZD 5305; AZD-5305. CAS No. 2589531-76-8. Molecular formula: C22H26N6O2. Mole weight: 406.48. | |
| AZD-5363 | AZD-5363 is an orally available inhibitor of the serine / threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AZD-5363 binds to and inhibits all AKT isoforms. This agent may be used as monotherapy or combination therapy for a variety of human cancers. Alternative Names: AZD5363; AZD 5363; Capivasertib. Grades: 98%. CAS No. 1143532-39-1. Molecular formula: C21H25ClN6O2. Mole weight: 428.9152. | |
| AZD6482 | AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ. Phase 1. Alternative Names: KIN193; AZD6482; KIN 193; AZD 6482; KIN-193; AZD-6482. Grades: >98%. CAS No. 1173900-33-8. Molecular formula: C22H24N4O4. Mole weight: 408.45. | |
| AZD8797 | AZD8797 is a selective allosteric non-competitive modulator of the human CX3CR1 receptor (Ki = 3.9 nM), binding CX3CR1 and effecting G-protein signalling and β-arrestin recruitment in a biased way. AZD8797 has a 720 fold selectivity for CX3CR1 receptor over the CXCR2 receptor, a 246-fold selectivity versus hCCR1 and 187-fold versus hCCR2 and no significant antagonism of the CCR4, CCR5, CCR6, CXCR3, and CXCR5 receptors. Alternative Names: AZD8797; AZD-8797; AZD 8797; (2R)-2-[[2-amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol. CAS No. 911715-90-7. Molecular formula: C19H25N5OS2. Mole weight: 403.56. | |
| AZD-9291 | AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. AZD 9291 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type form of the receptor (IC50 = 480 nM). It binds the related IGF1R and hERG receptors with significantly reduced potency (IC50s = 2.9 and 16.2 μM, respectively). Uses: For research used only. Alternative Names: Mereletinib; AZD9291; AZD 9291; Osimertinib. Grades: 98%. CAS No. 1421373-65-0. Molecular formula: C28H33N7O2. Mole weight: 499.61. | |
| AZD9291DA | AZD9291-DA is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. Uses: For research used only. Alternative Names: AZD9291-Des acryl analogue; AZD9291 Des acryl precursor; Mutated EGFR-IN-1; N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine; N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-N4-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine; SCHEMBL14660679. Grades: 0.98. CAS No. 1421372-66-8. Molecular formula: C25H31N7O. Mole weight: 445.571. | |
| AZD9496 | AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. Alternative Names: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid; AZD9496; AZD-9496; AZD 9496. Grades: 98%. CAS No. 1639042-08-2. Molecular formula: C25H25F3N2O2. Mole weight: 442.48. | |
| Azelaic acid | Azelaic acid is a naturally occurring saturated binary carboxylic acid containing nine carbon atoms, which is an important medium and long chain dibasic acid. Azelaic acid has been used in cosmetics for a long time. It has the function of inhibiting excessive secretion of oil, removing acne and freckles, and whitening skin, and it is very safe. Uses: Azelaic acid could be produced by ozone cracking of unsaturated fatty acid and is commonly used in grease, cosmetics and pharmaceuticals. Alternative Names: Finacea; Anchoic acid; Azelex; Lepargylic acid; 1,7-Heptanedicarboxylic acid; Skinoren; 1,9-Nonanedioic acid; Heptanedicarboxylic acid; n-Nonanedioic acid. Grades: ≥98%. CAS No. 123-99-9. Molecular formula: C9H16O4. Mole weight: 188.22. | |
| Azelaic Acid Monoethyl Ester | Azelaic Acid Monoethyl Ester. Uses: A novel c-11 epoxy fatty acid, from timothy chokes, stromata of e. typhina, has antifungal activity. Alternative Names: Nonanedioic Acid 1-Ethyl Ester; Azelaic Acid Ethyl Ester; Nonanedioic Acid Monoethyl Ester; 8-(Ethoxycarbonyl)octanoic Acid; Ethyl Hydrogen Azelaate; Monoethyl Nonanedioate. CAS No. 1593-55-1. Molecular formula: C11H20O4. Mole weight: 216.27. | |
| Azetidine | Azetidine. Alternative Names: Azacyclobutane; Trimethylene imine; Trimethylenimine; 1,3-Propylenimine. Grades: 98%. CAS No. 503-29-7. Molecular formula: C3H7N. Mole weight: 57.09. | |
| Azetidine-2-methanol | Azetidine-2-methanol. CAS No. 250274-91-0. Molecular formula: C4H9NO. Mole weight: 87.12. | |
| Azide-fluor 488 | Azide-fluor 488 is a green-fluorescent probe is reactive with terminal alkynes via a copper-catalyzed click reaction. Alternative Names: Rhodamine 110-azide; Alexa Fluor 488 Azide. Molecular formula: C29H30N6O7. Mole weight: 574.59. | |
| Azido-PEG3-amine | A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins. Alternative Names: Azide-PEG4-Amine;1-Amino-11-azido-3,6,9-trioxaundecane; Amino-PEG3-C2-Azido; 1-[2-(2-aminoethoxy)ethoxy]-2-(2-azidoethoxy)ethane; N3-PEG3-CH2CH2NH2; Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; 11-Azido-3,6,9-trioxaundecan-1-amine; 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethan-1-amine. Grades: ≥95%. CAS No. 134179-38-7. Molecular formula: C8H18N4O3. Mole weight: 218.25. | |
| Azido-PEG4-amine | N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Alternative Names: 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane. Grades: ≥95%. CAS No. 951671-92-4. Molecular formula: C10H22N4O4. Mole weight: 262.31. | |
| azidotributyltin | azidotributyltin. Alternative Names: TRI-N-BUTYLAZIDOTIN; TRIBUTYLTIN AZIDE; AZIDOTRIBUTYLTIN; azidotributyltin(iv); Azidotributylstannane; Nsc179738. Grades: 95%. CAS No. 17846-68-3. Molecular formula: C12H27N3Sn. Mole weight: 332.07. | |
| Aziridine, homopolymer, reaction products with epichlorohydrin | Aziridine, homopolymer, reaction products with epichlorohydrin. Alternative Names: Epomins(R); Ethylene imine polymer; Ethyleneimine Resin; Polyethyleneimine on silica beads; Polyethyleneimine, epichlorohydrin modified; Polyethyleneimine P-70; Polyethyleneimine, branched. CAS No. 68307-89-1. Molecular formula: (C3H5ClO.C2H5N)x. | |
| Azithromycin EP Impurity A | An impurity of Azithromycin. Azithromycin, derived from erythromycin, is an antibiotic. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. It is an azalide, a subclass of macrolide antibiotics and is one of the world's best-selling antibiotics. Alternative Names: Azaerythromycin A; 9-Deoxo-9a-aza-9a-homoerythromycin A; Desmethyl Azithromycin. Grades: > 98%. CAS No. 76801-85-9. Molecular formula: C37H70N2O12. Mole weight: 734.96. | |
| Azithromycin EP Impurity B | An impurity of Azithromycin. Azithromycin B is a macrolide antibiotic that is structurally related to erythromycin and contains a 15-membered ring. It is known for its broad-spectrum activity against a variety of bacterial infections. Azithromycin works by binding to the 50S ribosomal subunit of bacteria, which inhibits their protein synthesis. This medication is used to treat several types of infections, including respiratory, enteric, and genitourinary infections, as well as some sexually transmitted diseases. Alternative Names: Azithromycin B; 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-4,10-dihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3R,4R,5R,8R,10R,11R,12R,13S,14R)-; 3-Deoxyazithromycin; Azithromycin Impurity B. Grades: >95%. CAS No. 307974-61-4. Molecular formula: C38H72N2O11. Mole weight: 733.00. | |
| Azithromycin EP Impurity C | An impurity of Azithromycin. Azithromycin is an antibiotic for the treatment of bacterial infections including middle ear infections, strep throat, pneumonia, and other sexually transmitted infections. Alternative Names: Azithromycin C; 3''-O-Demethylazithromycin. Grades: > 95%. CAS No. 620169-47-3. Molecular formula: C37H70N2O12. Mole weight: 734.97. | |
| Azithromycin EP Impurity E | Azithromycin EP Impurity E is one of several different impurities found in the macrolide antibiotic, azithromycin. It can be used as a reference standard for azithromycin impurity tracing. Alternative Names: 3'-(N,N-Didemethyl)azithromycin; aminoazithromycin; N',N'-Di(desmethyl) azithromycin; 3'-N,N-Di(desmethyl) azithromycin. Grades: > 95%. CAS No. 612069-27-9. Molecular formula: C36H68N2O12. Mole weight: 720.95. | |
| Azithromycin EP Impurity F | Azithromycin EP Impurity F is one of several different impurities found in the macrolide antibiotic, azithromycin. It can be used as a trace impurity reference standard. Alternative Names: 3'-N-Demethyl-3'-N-formylazithromycin; Azithromycin Related Compound F. Grades: 95%. CAS No. 612069-28-0. Molecular formula: C38H70N2O13. Mole weight: 762.99. | |
| Azithromycin EP Impurity M | Azithromycin EP Impurity M is a degradation product of Azithromycin. Alternative Names: 3'-(N,N-Didemethyl)-3'-N-formylazithromycin; 3'-N,N-Di(desmethyl)-3'-N-formyl Azithromycin. Grades: > 95%. CAS No. 765927-71-7. Molecular formula: C37H68N2O13. Mole weight: 748.96. | |
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