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PIPERLONGUMINE
Piperlongumine, also known as Piplartine , is a biologically active alkaloid/amide from peppers, as from long pepper (Piper longum L. - Piperaceae). Long pepper is one of the most widely used in Ayurvedic medicine, which is used to treat many diseases, including tumors. The reported pharmacological activities of piplartine include cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, and schistosomicidal activities. Among the multiple pharmacological effects of piplartine, its anticancer property is the most promising. Therefore, the preclinical anticancer potential of piplartine has been extensively investigated, which recently resulted in one patent. This compound is selectively cytotoxic against cancer cells by induction of oxidative stress, induces genotoxicity, as an alternative strategy to killing tumor cells, has excellent oral bioavailability in mice, inhibits tumor growth in mice, and presents only weak systemic toxicity. Synonyms: Piplartine; 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone; (E)-5,6-Dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)-pyridinone; Piplartin; (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one; NSC-794671. Grade: ≥98%. CAS No. 20069-09-4. Mole
Piracetam
Piracetam is a prototypical nootropic which modulates Na+-flux at AMPA receptors. Synonyms: MK-803; MK 803; MK803. Grade: >98%. CAS No. 7491-74-9. Molecular formula: C6H10N2O2. Mole weight: 142.16.
Piracetam-[d8]
Piracetam-[d8] is the labelled analogue of Piracetam. Piracetam can be used mainly for myoclonus in UK. Synonyms: Piracetam D8; 2-Oxo-1-pyrrolidineacetamide-d8; (2-Oxopyrrolidino)acetamide-d8; 2-(2-Oxopyrrolidin-1-yl)acetamide-d8; Avigilen-d8. Grade: 98% by HPLC; 99% atom D. CAS No. 1329799-64-5. Molecular formula: C6H2D8N2O2. Mole weight: 150.21.
Pirbuterol-[d9] acetate
Pirbuterol-[d9] acetate is the labelled analogue of Pirbuterol acetate, which is a short-acting β2 adrenoreceptor agonist. Synonyms: Pirbuterol-D9 acetate; 6-(2-tert-Butyl-D9-amino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate; α6-[[(1,1-Dimethylethyl)amino]methyl]-3-hydroxy-2,6-pyridinedimethanol-d9 Monoacetate (Salt); Maxair-d9; Spirolair-d9. Grade: 95% by HPLC; 98% atom D. CAS No. 1431291-46-1. Molecular formula: C12H11D9N2O3.C2H4O2. Mole weight: 309.41.
Pirfenidone
Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Synonyms: S-7701; S 7701; S7701; AMR69; AMR-69; AMR 69; Pirespa; Pirfenex; Deskar, Esbriet; Etuary. Grade: >98%. CAS No. 53179-13-8. Molecular formula: C12H11NO. Mole weight: 185.22.
Pirfenidone-[d5]
Pirfenidone-[d5] is the labelled analogue of Pirfenidone, which is an inhibitor for TGF-β production and TGF-β stimulated collagen production with anti-fibrotic and anti-inflammatory properties. Pirfenidone is a medication used for the treatment of idiopathic pulmonary fibrosis. Synonyms: Pirfenidone-d5; 5-Methyl-N-phenyl-2-1H-pyridone-d5. Grade: 95% by HPLC; 95% atom D. CAS No. 1020719-62-3. Molecular formula: C12H6D5NO. Mole weight: 190.25.
Piribedil-[d8]
The deuterated labelled form of Piribedil, a piperazine derivative, which has been found to be an α2-adrenergic antagonist and could be used to improve the cognition and sensory neurological disorders. Synonyms: Piribedil D8; Trivastal-d8; Trivastan-d8. Grade: >98%. CAS No. 1398044-45-5. Molecular formula: C16H10D8N4O2. Mole weight: 306.34.
Pirimicarb-[d6]
Pirimicarb-[d6] is the labelled analogue of Pirimicarb. Pirimicarb is an insecticide used for control of aphids on vegetable, cereal and orchard crops. Synonyms: Pirimicarb D6; N,N-di(methyl-d3)-, 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester Carbamic acid; 2-Dimethylamino-5,6-dimethyl-4-pyrimidinyl dimethyl-d6-carbamate. Grade: 95% by HPLC; 98% atom D. CAS No. 1015854-66-6. Molecular formula: C11H12D6N4O2. Mole weight: 244.32.
Pirimiphos-methyl-[d6]
Pirimiphos-methyl-[d6] is the labelled analogue of Pirimiphos-methyl, which is used as an insecticide. Synonyms: Pirimiphos-methyl D6; Phosphorothioic Acid O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-Dimethyl Ester-d6. Grade: 95% by HPLC; 98% atom D. CAS No. 1793055-06-7. Molecular formula: C11H14D6N3O3PS. Mole weight: 311.37.
Pirlimycin-[d12] Hydrochloride (Mixture of Diastereomers)
Pirlimycin-[d12] Hydrochloride (Mixture of Diastereomers) is the labelled salt of Pirlimycin, which is a semi-synthetic lincosaminide antibiotic. Synonyms: Pirlimycin-d12 Hydrochloride; (2S-cis)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside-d12 Hydrochloride; Pirsue-d12. Grade: 97%. Molecular formula: C17H19D12ClN2O5S.HCl. Mole weight: 460.50.
Pirlindole-[d4]
Pirlindole-[d4] is the labelled analogue of Pirlindole. Pirlindole, a tetracyclic compound with potential antidepressant effect, is a selective reversible inhibitor of monoamine oxidase A. Synonyms: Pirlindole-d4; 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole-d4; pirlindol-d4; 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole-d4. Grade: >95%. CAS No. 1801646-26-3. Molecular formula: C15H14D4N2. Mole weight: 230.34.
Piroxicam-[d3]
Piroxicam-[d3] is the labelled analogue of Piroxicam, which is a non-selective COX inhibitor and a nonsteroidal anti-inflammatory drug used to relieve the symptoms of painful inflammatory conditions like arthritis. Synonyms: Piroxicam-D3; 4-Hydroxy-2-(methyl-d3)-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide; Artroxicam-d3; Baxo-d3; Bruxicam-d3; Caliment-d3; Roxicam-d3; Roxiden-d3; Sasulen-d3; Solocalm-d3; Piroxicam-(methyl-d3). Grade: ≥98%; ≥99% atom D. CAS No. 942047-64-5. Molecular formula: C15H10D3N3O4S. Mole weight: 334.37.
Pitavastatin calcium
Pitavastatin calcium is a novel member of the medication class of statins. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt; Flovas; Livalo; NK 104; NK 104 (acid); Pitava 1; Pitavastatin Hemicalcium; Pitavastatin Calcium Salt; calcium (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Nisvastatin; NK-104; P 872441; P-872441; P872441. Grade: 96%. CAS No. 147526-32-7. Molecular formula: C50H46CaF2N2O8. Mole weight: 880.98.
Pitavastatin-[d4] Calcium Salt
Pitavastatin-[d4] Calcium Salt, is the labelled analogue of Pitavastatin. Pitavastatin is a member of the blood cholesterol lowering medication class of statins. It is an inhibitor of HMG-CoA reductase. Synonyms: Pitavastatin D4 Calcium Salt. Grade: > 95%. Molecular formula: C50H38D8F2N2O8Ca. Mole weight: 889.03.
Pitavastatin ethyl ester
Pitavastatin Ethyl Ester is used as a reactant in the preparation of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (E)-(3R,5S)-7-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester; (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Ethyl Ester; 3R,5S-DOLE; Pitavastatin Impurity 17; 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, ethyl ester, (3R,5S,6E)-. Grade: ≥95%. CAS No. 167073-19-0. Molecular formula: C27H28FNO4. Mole weight: 449.51.
Pitavastatin Lactone-[d4]
One of the isotopic labelled metabolites of Pitavastatin, which has a potent cholesterol-lowering action. Synonyms: Pitavastatin Lactone D4. Grade: >98%. Molecular formula: C25H18D4FNO3. Mole weight: 407.48.
Pladienolide B
a potent pre-mRNA splicing inhibitor. Pladienolide B has shown strong inhibitory effect against activity and growth of various cell lines via targeting SF3b. Synonyms: (3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-7-acetoxy-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-triene-11-olide; [(2~{S},3~{S},4~{E},6~{S},7~{R},10~{R})-3,7-dimethyl-2-[(2~{E},4~{E},6~{S})-6-methyl-7-[(2~{R},3~{R})-3-[(2~{R},3~{S})-3-oxidanylpentan-2-yl]oxiran-2-yl]hepta-2,4-dien-2-yl]-7,10-bis(oxidanyl)-12-oxidanylidene-1-oxacyclododec-4-en-6-yl] ethanoate; Pla-B, 5. Grade: ≥95% by HPLC. CAS No. 445493-23-2. Molecular formula: C30H48O8. Mole weight: 536.71.
Plerixafor-[d4]
Plerixafor-[d4] is the labelled analogue of Plerixafor, which is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5. 7 nM, respectively. Synonyms: Plerixafor D4; 1,1'-[(2H4)-1,4-Phenylenebis(methylene)]bis(1,4,8,11-tetraazacyclotetradecane). Grade: 95% by HPLC; 95% atom D. CAS No. 1246819-87-3. Molecular formula: C28H50D4N8. Mole weight: 506.81.
Polyethylene-[d4]
Polyethylene-[d4]. Synonyms: Deuterated polyethylene. Grade: 98% atom D. CAS No. 25549-98-8. Molecular formula: (C2D4)n. Mole weight: 96.23.
Poly(Styrene-[d8]). Grade: 98% atom D. Molecular formula: [-C8D8-]n.
Pomalidomide-[d4]
Pomalidomide-[d4] is the labelled analogue of Pomalidomide, which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Synonyms: Pomalidomide D4; 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1416575-78-4. Molecular formula: C13H7D4N3O4. Mole weight: 277.27.
Pomalidomide-d5
Pomalidomide-d5 is a deuterated form of Pomalidomide. Pomalidomide is a third-generation immunomodulatory agent that functions as a molecular glue. It interacts with E3 ligase cereblon and induces the degradation of the essential Ikaros transcription factor. Synonyms: Pomalidomide D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1377838-49-7. Molecular formula: C13H6D5N3O4. Mole weight: 278.27.
Ponatinib-[d8]
Ponatinib-[d8] is the labelled analogue of Ponatinib, which is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0. 37 nM, 1. 1 nM, 1. 5 nM, 2. 2 nM and 5. 4 nM, respectively. Synonyms: Ponatinib D8; 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-3-(trifluoromethyl)phenyl]-benzamide. Grade: 95% by HPLC; 95% atom D. CAS No. 1562993-37-6. Molecular formula: C29H19D8F3N6O. Mole weight: 540.61.
Posaconazole-[d4]
Posaconazole-[d4] is the labelled analogue of Posaconazole, which is a sterol C14α demethylase inhibitor with an IC50 of 0. 25 nM. Posaconazole is a triazole antifungal medication. Synonyms: Posaconazole D4; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol-d4. Grade: 98% by HPLC; 98% atom D. CAS No. 1133712-26-1. Molecular formula: C37H38D4F2N8O4. Mole weight: 704.80.
Posaconazole-[d5]
Posaconazole-[d5], is the labelled analogue of Posaconazole, which is a sterol C14α demethylase inhibitor with an IC50 of 0.25 nM. Posaconazole is a triazole antifungal medication. Synonyms: Posaconazole D5. Grade: > 95%. CAS No. 1217785-83-5. Molecular formula: C37H37D5F2N8O4. Mole weight: 705.8.
Potassium benzylpenicillin
Penicillin G potassium is a fast-acting antibiotic, used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas. Uses: Anti-bacterial agents. Synonyms: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Potassium Salt; Penicillin G Potassium Salt; Benzylpenicillin Potassium; Cosmopen; Cristapen; Crytapen; Eskacillin; Falapen; Forpen; Hipercilina; Hyasorb; Hylenta; M-Cillin; Monopen; NSC 131815; Notaral; Pentid; Pentids; Potassium 6-(Phenylacetamido)penicillanate; Potassium Benzylpenicillinate; Potassium Penicillin G; Scotcil; Tabilin; Penicillin G potassium salt; Potassium benzylpenicillin. Grade: 98%. CAS No. 113-98-4. Molecular formula: C16H17KN2O4S. Mole weight: 372.48.
(±)-PPCC oxalate
(±)-PPCC oxalate is a selective sigma (σ) receptor ligand, which is noted to exhibit high affinity for σ1 and also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Synonyms: (S*,R*)-2-[(4-Hydroxy-4-phenyl-1-piperidinyl)methyl]-1-(4-methylphenyl)-cyclopropanecarboxylic acid methyl ester; (1R,2S)-rel-2-[(4-Hydroxy-4-phenyl-1-piperidinyl)methyl]-1-(4-methylphenyl)-cyclopropanecarboxylic Acid Methyl Ester Ethanedioate (2:1). Grade: ≥99% by HPLC. CAS No. 932736-91-9. Molecular formula: C24H29NO3.C2H2O4. Mole weight: 469.53.
Pramipexole-[d3]
Pramipexole-[d3] is the labelled analogue of Pramipexole. Pramipexole is used to treat symptoms of Parkinson's disease (stiffness, tremors, muscle spasms, and poor muscle control). Synonyms: Pramipexole D3; (S)-4,5,6,7-Tetrahydro-N6-(propyl-d3)-2,6-benzothiazolediamine Dihydrochloride. Grade: 98% by HPLC; 98% atom D. CAS No. 1217695-77-6. Molecular formula: C10H14D3N3S. Mole weight: 214.34.
Pramipexole-[d5] Dihydrochloride
Pramipexole-[d5] Dihydrochloride is the labelled analogue of Pramipexole, which is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist. Synonyms: Pramipexole D5 dihydrochloride; (S)-4,5,6,7-Tetrahydro-N6-propyl-d5-2,6-benzothiazolediamine Dihydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1217601-58-5. Molecular formula: C11H14D5ClN3S. Mole weight: 289.28.
Pramipexole dihydrochloride
The HCl salt form of pramipexole, a thiazole derivative, is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist which is one of the most classical targets in the treatment of Parkinson's disease. Ki: 3.9, 2.2, 0.5, and 5. Uses: The hcl salt form of pramipexole is an agonist of dopamine receptor d2, d3 and d4, especially used as d2-receptor agonist. Synonyms: (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine dihydrochloride; Pramipexole Dihydrochloride; Mirapex ER; Pramipexole hydrochloride; SND919; Mirapex; SUD 919CL2Y; SUD919CL2Y; U-98528E; Sifrol; SND 919; KNS-760704; SND-919; KNS 760704; KNS760704. Grade: 98%. CAS No. 104632-25-9. Molecular formula: C10H17N3S·2(HCl). Mole weight: 284.25.
Pranlukast-[d4]
Pranlukast-[d4], is the labelled analogue of Pranlukast. Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It can be used as an antiasthmatic. Synonyms: Pranlukast D4. Grade: 95% by CP; 98% atom D. Molecular formula: C27H19D4N5O4. Mole weight: 485.54.
Prasterone Sulfate-[d2] Sodium
Prasterone Sulfate-[d2] Sodium. Synonyms: Sodium Dehydroepiandrosterone-16,16-d2 Sulfate. Grade: 97 atom % D. CAS No. 352431-52-8. Molecular formula: C19H25D2NaO5S. Mole weight: 392.48.
Prasugrel
Prasugrel is a thienopyridine prodrug that is converted by esterases to a receptor antagonist for purinergic P2Y12 receptors. The blockade of P2Y12 receptor activation prevents platelet aggregation. Prasugrel is metabolized by the liver- and intestinal-dominant carboxylesterases CE1 and CE2 to give a mixture of four enantiomers that inhibit platelet aggregation. Synonyms: Effient; CS 747; LY640315; CS747; LY 640315; CS-747; LY-640315. Grade: 0.99. CAS No. 150322-43-3. Molecular formula: C20H20FNO3S. Mole weight: 373.442.
Prasugrel-[d3]
One of the isotopic labelled form of (±)-Prasugrel, which is a P2Y12(ADP receptor) inhibitor. Synonyms: (±)-Prasugrel-d3 (acetate-d3); (RS)-5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridinin-2-yl Acetate. Grade: 95% by HPLC; 98% atom D. CAS No. 1127253-02-4. Molecular formula: C20H17D3FNO3S. Mole weight: 376.46.
Prasugrel-[d4] Metabolite R-138727
An isotope labelled Prasugrel Metabolite derivative. Prasugrel is a platelet inhibitor. It can be used to prevent formation of blood clots. Synonyms: Prasugrel metabolite M3 D4. Grade: > 95%. CAS No. 1217222-86-0. Molecular formula: C18H16FNO3SD4. Mole weight: 353.45.
Prasugrel-[d5]
Prasugrel-[d5] is the labelled analogue of Prasugrel. Prasugrel is a platelet inhibitor. It can be used to prevent formation of blood clots. Synonyms: Prasugrel D5; 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-(cyclopropyl-d5)-2-(2-fluorophenyl)ethanone. Grade: 95% by HPLC; 95% atom D. CAS No. 1127252-92-9. Molecular formula: C20H15D5FNO3S. Mole weight: 378.47.
Prasugrel Metabolite M2-[d4]
Prasugrel Metabolite M2-[d4], is the labelled metabolite of Prasugrel. Prasugrel is a medication used to prevent formation of blood clots. It is a platelet inhibitor and an irreversible antagonist of P2Y12 ADP receptors. Synonyms: Prasugrel Metabolite M2 D4. Grade: 98% by CP; 98% atom D. Molecular formula: C18H14D4FNO2S. Mole weight: 335.43.
Pravastatin-[d3] Sodium Salt
Pravastatin-[d3] Sodium Salt is the labelled analogue of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: Pravastatin-d3 Sodium Salt. Grade: 95% by HPLC; 95% atom D. CAS No. 1329836-90-9. Molecular formula: C23H32D3NaO7. Mole weight: 449.53.
Pravastatin Lactone-[d3]
Pravastatin Lactone-[d3] is the labelled analogue of Pravastatin Lactone, which is a metabolite of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: Pravastatin Lactone D3; (2S)-2-(Methyl-d3)butanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Grade: 97%; ≥99% atom D. CAS No. 1217769-04-4. Molecular formula: C23H31D3O6. Mole weight: 409.54.
Praziquantel-[d11]
Praziquantel-[d11] is the labelled analogue of Praziquantel. Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Uses: The d11 isotope labelled praziquantel. Synonyms: Praziquantel-d11; 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-(pyrazino-d11)[2,1-a]isoquinolin-4-one. Grade: 95% by HPLC; 95% atom D. CAS No. 1246343-36-1. Molecular formula: C19H13D11N2O2. Mole weight: 323.47.
Prazobind-[d8]
Prazobind-[d8] is the labelled analogue of Prazobind. Prazobind is an α1-adrenergic receptor (AR) antagonist. Uses: Α1-adrenoceptor alkylating reagent. a labelled prazosin analog. Synonyms: Prazobind D8; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-(piperazine-d8). Grade: 95% by HPLC; 95% atom D. CAS No. 1189701-23-2. Molecular formula: C23H19D8N5O3. Mole weight: 429.54.
Prazosin-[d8]
An isotope labelled Prazosin. Prazosin is an inverse agonist at alpha-1 adrenergic receptor. Prazosin is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD). Synonyms: 4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-d8]-2-furanylmethanone; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonxyl) piperazine-d8; Adversuten-d8; Adverszuten-d8; Alpress LP-d8; Furazosin-d8; Lentopres-d8; NSC 292810-d8; Peripress-d8. Grade: >95%. CAS No. 1006717-55-0. Molecular formula: C19H13D8N5O4. Mole weight: 391.46.
Prednisone 21-acetate
A derivative of Prednisone.Prednisone is a synthetic corticosteroid drug. It can be used for the treatment of certain inflammatory diseases, some autoimmune diseases, and (at higher doses) some types of cancer. Synonyms: 21-(Acetyloxy)-17-hydroxy-pregna-1,4-diene-3,11,20-trione; 21-Acetoxy-17α-hydroxypregna-1,4-diene-3,11,20-trione; Prednisone Acetate; 1-Cortisone 21-Acetate; 1-Dehydrocortisone Acetate; Cortancyl; Delcortin; Δ-Corlin; Deltalone; Ferrosan; Nisone; NSC 10965. Grade: >98%. CAS No. 125-10-0. Molecular formula: C23H28O6. Mole weight: 400.46.
Pregnenolone-[17alpha,21,21,21-d4]
Pregnenolone-[17alpha,21,21,21-d4] is a labelled version of Pregnenolone. Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor- and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively. Synonyms: (3β)-3-Hydroxy-pregn-5-en-20-one-d4; (3β)-3-Hydroxypregn-5-en-20-one-d4; 5-Pregnenolone-d4; Arthenolone-d4; Bina-Skin-d4; Enelone-d4; NSC 1616-d4; Pregnolon-d4; Prenolon-d4; Regnosone-d4; Skinostelon-d4. CAS No. 61574-54-7. Molecular formula: C21H28D4O2. Mole weight: 320.50.
(+Pro5)-Alarelin
(+Pro5)-Alarelin is a modified form of Alarelin, a synthetic analog of Gonadotropin-releasing hormone (GnRH). This modification involves the introduction of a proline residue at the 5th position, which can alter its biological activity and pharmacological properties. Synonyms: Glp-His-Trp-Ser-Pro-Tyr-DAla-Leu-Arg-Pro-NHEt; H-Pyr-His-Trp-Ser-Pro-Tyr-D-Ala-Leu-Arg-Pro-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-prolyl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide; Glp-HWSPY-DAla-LRP-NHEt; Glp-HWYaLRP-NHEt. Grade: ≥95%. Molecular formula: C61H85N17O13. Mole weight: 1264.46.
Probenecid-d14
Probenecid-[d14] is the labelled analogue of Probenecid. Probenecid is a drug that increases the excretion of uric acid in the urine and can be used to treat gout and hyperuricemia. Synonyms: Probenecid-d14; 1189657-87-1; 4-[bis(1,1,2,2,3,3,3-heptadeuteriopropyl)sulfamoyl]benzoic acid; Probenecid-d14 (di-n-propyl-d14); 4[(Dipropylamino-d14)sulfonyl]benzoic Acid; HY-B0545S; DA-77072; CS-0201015; F91263. Grade: >95%. CAS No. 1189657-87-1. Molecular formula: C13H5D14NO4S. Mole weight: 299.45.
Procaine-[d4] Hydrochloride
An isotope labelled derivative of Procaine. Procaine is a local anesthetic drug and can be used to reduce the pain of intramuscular injection of penicillin. Synonyms: Procaine D4 Hydrochloride. Grade: 95% by CP; 99% atom D. Molecular formula: C13H17D4ClN2O2. Mole weight: 276.8.
Prochlorperazine-[d3] Dimesylate
An isotope labelled of Prochlorperazine. Prochlorperazine is a dopamine receptor antagonist as an antipsychotic agent. It can be used for the antiemetic treatment of nausea and vertigo. Synonyms: 2-Chloro-10-[3-(4-methyl-d3-1-piperazinyl)propyl]-10H-phenothiazine Dimethanesulfonate; 3-Chloro-10-[3-(4-methyl-d3-1-piperazinyl)propyl]phenothiazine Dimesylate; Novamin-d3; Tementyl-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 753432-54-1. Molecular formula: C22H29D3ClN3S2O6. Mole weight: 569.17.
Prochlorperazine-[d8]
An isotope labelled Prochlorperazine. Prochlorperazine is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo. Uses: The isotope labelled form of prochlorperazine. Synonyms: Compazine D8; Stemetil D8; [2H8]-Prochlorperazine. Grade: >98%. CAS No. 1215641-01-2. Molecular formula: C20H16D8ClN3S. Mole weight: 381.99.
Prochlorperazine-[d8] Dimaleate
Prochlorperazine-[d8] Dimaleate, is the labelled analogue of Prochlorperazine. Prochlorperazine is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents, which are used for the antiemetic treatment of nausea and vertigo. Synonyms: Prochlorperazine D8 Dimaleate. Grade: 97% by CP; 98% atom D. Molecular formula: C28H24D8ClN3O8S. Mole weight: 614.14.
Progesterone-2,2,4,6,6,17α,21,21,21-[d9]
Progesterone-2,2,4,6,6,17α,21,21,21-[d9] is a labelled analogue of progesterone. Progesterone (P4) is a natural steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Synonyms: 4-Pregnene-3,20-dione; Progesterone-d9. Grade: 98% by CP; 98% atom D. CAS No. 15775-74-3. Molecular formula: C21H21D9O2. Mole weight: 323.52.
Progesterone EP Impurity B
A metabolite of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Uses: Progestins. Synonyms: (20S)-20-hydroxypregn-4-en-3-one; Pregn-4-en-3-one, 20-hydroxy-, (20S)-; Pregn-4-en-3-one, 20α-hydroxy-; 20(S)-Hydroxyprogesterone; 20-Hydroxypregn-4-en-3-one; 20α-Dihydroprogesterone; 20α-Hydroxy-4-pregnen-3-one; 20α-Hydroxy-Δ4-pregnen-3-one; 20α-Hydroxydihydroprogesterone; 20α-Hydroxypregn-4-en-3-one; 20α-Hydroxyprogesterone; 20α-Progerol; 4-Pregnen-3-one-20α-ol; NSC 68630; Pregn-4-en-20α-ol-3-one; Pregn-4-ene-20α-ol-3-one; Progesterol-20α; Δ4-Pregnene-20α-ol-3-one; Δ4-Pregnen-20α-ol-3-one. Grade: ≥95%. CAS No. 145-14-2. Molecular formula: C21H32O2. Mole weight: 316.49.
Promecarb-[d3]
Promecarb-[d3]. Synonyms: Promecarb D3; 3-Methyl-5-(1-methylethyl)-phenol 1-(N-Methylcarbamate)-d3; Methyl-carbamic Acid m-Cym-5-yl Ester-d3; 3-Methyl-5-(1-methylethyl)-phenol Methylcarbamate-d3. Grade: 99% atom D. CAS No. 1219799-11-7. Molecular formula: C12H14D3NO2. Mole weight: 210.29.
Propadiene-[d4]
Propadiene-[d4]. Synonyms: Propadiene D4. Grade: 95% atom D. CAS No. 1482-85-5. Molecular formula: C3D4. Mole weight: 44.09.
Propafenone-1,1,2,3,3-[d5] Hydrochloride
Propafenone-1,1,2,3,3-[d5] Hydrochloride is the labelled salt of Propafenone. Propafenone is an anti-arrhythmic medication. It can be used for the treatment of illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. Propafenone Hydrochloride is a sodium channel protein inhibitor. Synonyms: Propafenone-d5 Hydrochloride; 1-[2-[2-Hydroxy-3-(propylamino)propoxy-d5]phenyl]-3-phenyl-1-propanone Hydrochloride; 2'-[2-Hydroxy-3-(propylamino)propoxy-d5]-3-phenylpropiophenone Hydrochloride; Arythmol-d5; Pronon-d5; Rythmol-d5; Rytmonorm-d5. Grade: ≥98%; ≥99% atom D. CAS No. 1346605-05-7. Molecular formula: C21H22D5NO3.HCl. Mole weight: 382.94.
Propafenone-[d7] HCl
Propafenone-[d7] HCl is the labelled analogue of Propafenone, which is a sodium channel blocker and commonly used in the treatment of arrhythmia. Uses: The hydrochloride salt form of d7 labelled propafenone. Synonyms: Propafenone D7 HCl. Grade: 99% atom D. CAS No. 1219799-06-0. Molecular formula: C21H21D7ClNO3. Mole weight: 384.95.
Propafenone hydrochloride
Propafenone is a Class 1C antiarrhythmic as sodium channel blocker by slowing the influx of sodium ions into the cardiac muscle cells. Uses: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. it also has weak beta-blocking activity. Synonyms: 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone; 2-(2'-Hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone. Grade: ≥98%. CAS No. 34183-22-7. Molecular formula: C21H27NO3·HCl. Mole weight: 377.91.
Propanil-[d5]
Propanil-[d5] is the labelled analogue of Propanil. Propanil is a widely used herbicide. It can be used to control weed growth in rice fields. Synonyms: Propanil D5; 3',4'-Dichloropropionanilide-d5. Grade: 95% by HPLC; 95% atom D. CAS No. 1398065-82-1. Molecular formula: C9H4D5Cl2NO. Mole weight: 223.11.
Propanoyl-[d5] Chloride
Propanoyl-[d5] Chloride. Synonyms: Propanoyl-D5 Chloride. Grade: 98% atom D. CAS No. 352439-04-4. Molecular formula: C3D5ClO. Mole weight: 97.56.
Propantheline-[d3] Bromide (N-methyl-[d3])
An isotope labelled of Propantheline bromide. Propantheline bromide is an antimuscarinic agent that can be used for the treatment of excessive sweating,cramps or spasms of the stomach, intestines or bladder, and involuntary urination. Synonyms: N-(2-((9H-Xanthene-9-carbonyl)oxy)ethyl)-N-isopropyl-N-(methyl-d3)propan-2-aminium bromide. Grade: 95% by HPLC; 99% atom D. CAS No. 64717-35-7. Molecular formula: C23H27D3NO3Br. Mole weight: 451.42.
Propazine-[13C3]
Propazine-[13C3] is the labelled analogue of Propazine. Propazine is a herbicide used to control sweet sorghum broadleaf weeds and annual grasses. Synonyms: Propazine (Ring-13C3); Prozinex-13C3; Propazine-13C3; Gesamil-13C3; Milogard-13C3; Plantulin-13C3; Propasin-13C3; Primatol P-13C3; 2-Chloro-4,6-bis(isopropylamino)-s-triazine-13C3; 2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine-13C3; 6-Chloro-N,N'-bis(1-methylethyl)-1,3,5-triazine-2,4-diamine-13C3; 6-chloro-N2,N4-diisopropyl-1,3,5-triazine-2,4-diamine-13C3. Grade: 98%; 99% atom 13C. CAS No. 446276-68-2. Molecular formula: C6[13C]3H16ClN5. Mole weight: 232.69.
Propazine-[d6]
Propazine-[d6] is a labelled Propazine. Propazine is an herbicide used for control of broadleaf weeds and annual grasses in sweet sorghum. Synonyms: Propazine D6; 6-chloro-N2-isopropyl-N4-(propan-2-yl-1,1,1,3,3,3-d6)-1,3,5-triazine-2,4-diamine. Grade: 95% by CP; 98% atom D. CAS No. 1655498-05-7. Molecular formula: C9H9D6ClN5. Mole weight: 235.749.
Propene-[1,1,2-d3]
Propene-[1,1,2-d3]. Synonyms: Propene-1,1,2-D3. Grade: 98% atom D. CAS No. 1517-50-6. Molecular formula: C3H3D3. Mole weight: 45.1.
Propene-[1-13C]
Labelled Propene. Propene is used to produce polypropylene (plastic) and in the manufacture ofacetone, isopropanol, cumene, and propyleneoxide. Synonyms: Propene-1-13C. Grade: 99% atom 13C. CAS No. 89490-92-6. Molecular formula: C2[13C]H6. Mole weight: 43.07.
Propene-[1,1-d2]
Propene-[1,1-d2]. Synonyms: Propene-1,1-D2. Grade: 98% atom D. CAS No. 1517-49-3. Molecular formula: C3H4D2. Mole weight: 44.09.
Propene-[1-d]
Propene-[1-d]. Synonyms: Propene-1-d1. Grade: 98% atom D. CAS No. 1560-60-7. Molecular formula: C3H5D. Mole weight: 43.09.
Propene-[2-13C]
Labelled Propene. Propene is used to produce polypropylene (plastic) and in the manufacture ofacetone, isopropanol, cumene, and propyleneoxide. Synonyms: Propene-2-13C. Grade: 99% atom 13C. CAS No. 37020-81-8. Molecular formula: C2[13C]H6. Mole weight: 43.07.
Propene-[2-d]
Propene-[2-d]. Synonyms: Propene-2-D1; 2-deuteropropylene. Grade: 98% atom D. CAS No. 1184-59-4. Molecular formula: C3H5D. Mole weight: 43.09.
Propene-[3-13C]
Labelled Propene. Propene is used to produce polypropylene (plastic) and in the manufacture ofacetone, isopropanol, cumene, and propyleneoxide. Synonyms: Propene-3-13C. Grade: 99% atom 13C. CAS No. 89490-91-5. Molecular formula: C2[13C]H6. Mole weight: 43.07.