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| Product | Description | |
|---|---|---|
| N-Demethyl Trimebutine-[d5] Hydrochloride | N-Demethyl Trimebutine-[d5] Hydrochloride is the labelled analogue of N-Demethyl Trimebutine Hydrochloride, which is the main bioactive metabolite of Trimebutine. Trimebutine is an opioid receptor agonist used as an antispasmodic. Synonyms: N-Demethyl Trimebutine-d5 Hydrochloride; 3,4,5-Trimethoxybenzoic Acid 2-(Methylamino)-2-phenylbutyl-d5 Ester Hydrochloride; N-Monodesmethyltrimebutine-d5 Hydrochloride; JO 1069-d5 Hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1286632-72-1. Molecular formula: C21H23D5ClNO5. Mole weight: 414.93. |  |
| N-Demethyl Vandetanib-[d4] | N-Demethyl Vandetanib-[d4] is the labelled analogue of N-Desmethyl Vandetanib, which is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Synonyms: N-Demethyl Vandetanib D4; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[4-(piperidinyl-d4)methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[[(piperidin-4-yl)-d4]methoxy]quinazoline. Grade: 95% by HPLC; 98% atom D. CAS No. 1346603-93-7. Molecular formula: C21H18D4BrFN4O2. Mole weight: 465.36. | |
| N-Desbutyldronedarone-[d6] hydrochloride | N-Desbutyldronedarone-[d6] hydrochloride is the labelled analogue of N-Desbutyldronedarone hydrochloride, which is a metabolite of Dronedarone. Dronedarone is a medication used for the treatment of cardiac arrhythmias. Synonyms: N-Desbutyldronedarone hydrochloride D6; N-Desbutyl Dronedarone-d6 HCl; N-(2-Butyl-3-(4-(3-(butylamino)propoxy-1,1,2,2,3,3-d6)benzoyl)benzofuran-5-yl)methanesulfonamide Hydrochloride; Dronedarone Impurity D-d6; Dronedarone USP Related Compound A-d6. Grade: >95%. CAS No. 1346598-70-6. Molecular formula: C27H30D6N2O5S.HCl. Mole weight: 543.15. | |
| N-Desbutyl Lumefantrine-[d9] (E/Z-Mixture) | N-Desbutyl Lumefantrine-[d9] is the labelled analogue of N-Desbutyl Lumefantrine, which is a metabolite of Lumefantrine. Synonyms: N-Desbutyl Lumefantrine D9; α-[(Butylamino-d9)methyl]-2,7-dichloro-9-[(4-chlorophenyl)methylene]-9H-fluorene-4-methanol; Desbutyl Lumefantrine-d9 (E/Z-Mixture). Grade: ≥96% by HPLC; ≥98% atom D. CAS No. 1346606-35-6. Molecular formula: C26H15D9Cl3NO. Mole weight: 481.89. | |
| N-Desethyl Amodiaquine-[d5] Dihydrochloride | N-Desethyl Amodiaquine-[d5] Dihydrochloride is the labelled analogue of N-Desethyl Amodiaquine Dihydrochloride, which is a metabolite of Amodiaquine, an antimalarial. Synonyms: N-Desethyl Amodiaquine-D5 Dihydrochloride; 4-[(7-Chloro-4-quinolinyl)amino]-2-[(ethyl-d5-amino)methyl]phenol Dihydrochloride; Monodesethylamodiaquine-d5 Dihydrochloride; Desethylamodiaquine-d5 Dihydrochloride. Grade: ≥95% by HPLC; ≥99% atom D. CAS No. 1216894-33-5. Molecular formula: C18H15D5Cl3N3O. Mole weight: 405.76. | |
| N-Desethyl Etifoxine-[d5] | N-Desethyl Etifoxine-[d5] is the labelled analogue of N-Desethyl Etifoxine, which is a derivative of Etifoxine. Synonyms: N-Desethyl Etifoxine-d5; 6-Chloro-4-methyl-4-(phenyl-d5)-4H-3,1-benzoxazin-2-amine; 2-Amino-6-chloro-4-methyl-4-(phenyl-d5)-4H-3,1-benzoxazine. Grade: >95%. CAS No. 1346602-46-7. Molecular formula: C15H8D5ClN2O. Mole weight: 277.77. | |
| N-Desethyl Milnacipran-[d5] | N-Desethyl Milnacipran-[d5] is the labelled analogue of N-Desethyl Milnacipran, which is a metabolite of Milnacipran. Synonyms: N-Desethyl Milnacipran D5; (1R,2S)-rel-2-(Aminomethyl)-N-(ethyl-d5)-1-phenylcyclopropanecarboxamide; cis-2-(Aminomethyl)-N-(ethy-d5)-1-phenylcyclopropanecarboxamide; N-Deethylated Milnacipran-d5. Grade: >95%. CAS No. 1217609-30-7. Molecular formula: C13H13D5N2O. Mole weight: 223.33. | |
| N-Desethyl Oxybutynin-[d5] Hydrochloride | A labelled impurity of Oxybutynin which belongs to a class of drugs called anticholinergics/antimuscarinics. Synonyms: Rac Desethyl Oxybutynin-d5 Hydrochloride; N-Desethyl Oxybutynin D5 Hydrochloride. Grade: > 95%. CAS No. 1173018-49-9. Molecular formula: C20H22NO3D5·HCl. Mole weight: 370.93. | |
| N-Desethyl Vardenafil-[d8] | N-Desethyl Vardenafil-[d8] is the labelled analogue of N-Desethyl Vardenafil, which is a metabolite of Vardenafil. Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction. Synonyms: N-Desethyl Vardenafil D8; 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazine-d8. Grade: 97%; ≥98% atom D. CAS No. 1184985-26-9. Molecular formula: C21H20D8N6O4S. Mole weight: 468.60. | |
| N-Deshydroxyethyl Dasatinib-[d8] | N-Deshydroxyethyl Dasatinib-[d8] is the labelled analogue of N-Deshydroxyethyl Dasatinib, which is a metabolite of Dasatinib. Synonyms: N-Deshydroxyethyl Dasatinib D8; N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl-d8)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib Metabolite M4-d8. Grade: ≥97% by HPLC; ≥98% atom D. CAS No. 1189998-96-6. Molecular formula: C20H14D8ClN7OS. Mole weight: 452.00. | |
| N-Desmethyl-4-hydroxy Tamoxifen-[d5] (E/Z Mixture) | N-Desmethyl-4-hydroxy Tamoxifen-[d5] (E/Z Mixture) is the labelled analogue of N-Desmethyl-4-hydroxy Tamoxifen (E/Z Mixture), which is an impurity of Tamoxifen. Tamoxifen is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: N-Desmethyl-4-hydroxy Tamoxifen-d5 (1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl-d5]phenol; (E/Z)-Endoxifen-d5. Grade: 96%. CAS No. 1584173-54-5. Molecular formula: C25H22D5NO2. Mole weight: 378.52. | |
| N-Desmethyl Asenapine-[d4] Hydrochloride | N-Desmethyl Asenapine-[d4] Hydrochloride is the labelled analogue of N-Desmethyl Asenapine, which is a metabolite of Asenapine. Uses: Labelled asenapine (a788000) metabolite. Synonyms: N-Desmethyl Asenapine-d4 Hydrochloride. Grade: 95% atom D. CAS No. 1246820-54-1. Molecular formula: C16H11D4Cl2NO. Mole weight: 312.23. | |
| N-Desmethyldiltiazem-[d5] Maleate | N-Desmethyldiltiazem-[d5] Maleate is the labelled analogue of N-Desmethyldiltiazem Maleate, which is a metabolite of Diltiazem. Diltiazem is a nondihydropyridine calcium channel blocker which can be used in the treatment of hypertension. Synonyms: N-Desmethyldiltiazem-d5 Maleate; (2S-cis)-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one-d5 Maleate; N-Demethyldiltiazem-d5 Maleate; N-Monodesmethyldiltiazem-d5 Maleate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C21H19D5N2O4S.C4H4O4. Mole weight: 521.59. | |
| N-Desmethyl Dovitinib-[d8] | N-Desmethyl Dovitinib-[d8] is the labelled analogue of N-Desmethyl Dovitinib, which is a derivative of Dovitinib. Dovitinib is a receptor tyrosine kinase (RTK) inhibitor that exhibits a suppressive effect on tumor growth. Synonyms: N-Desmethyl Dovitinib D8; 4-Amino-5-fluoro-3-[6-(1-piperazinyl-d8)-1H-benzimidazol-2-yl]-2(1H)-quinolinone. Grade: >95%. CAS No. 1246814-93-6. Molecular formula: C20H11D8FN6O. Mole weight: 386.45. | |
| N-Desmethyl Enzalutamide-[d6] | N-Desmethyl Enzalutamide-[d6] is the labelled analogue of N-Desmethyl Enzalutamide, which is an impurity of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist in LNCaP cells. Synonyms: 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-bis(methyl-d3)-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide; N-Desmethyl Enzalutamide-d6; 4-[3-[4-Cyano-3-(trifluoromethyl)?phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide-d6; N-Desmethylenzalutamide-d6. Grade: >95%. CAS No. 2748567-63-5. Molecular formula: C20H8D6F4N4O2S. Mole weight: 456.45. | |
| N-Desmethyl Imatinib-[d4] | N-Desmethyl Imatinib-[d4] is the labelled analogue of N-Desmethyl Imatinib, which is a metabolite of Imatinib. Synonyms: Desmethyl imatinib D4; N-Desmethyl Imatinib-d4; N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide-d4; N-Desmethyl Gleevec-d4; Norimatinib-d4; Imatinib EP Impurity C-d4. Grade: 95% by HPLC; 98% atom D. Molecular formula: C28H25D4N7O. Mole weight: 483.60. | |
| N-Desmethyl Imatinib-[d8] | N-Desmethyl Imatinib-[d8] is a deuterated metabolite of gleevec, a tyrosine kinase inhibitor specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Synonyms: N-Desmethyl Imatinib D8; N-Desmethyl Gleevec-d8. Grade: ≥96% by HPLC; ≥98% atom D. CAS No. 1185103-28-9. Molecular formula: C28H21D8N7O. Mole weight: 487.64. | |
| N-Desmethyl Ivabradine-[d4] Hydrochloride | N-Desmethyl Ivabradine-[d4] Hydrochloride is the labelled analogue of N-Desmethyl Ivabradine Hydrochloride, which is a metabolite of Ivabradine. Ivabradine can be used to treat chronic stable angina pectoris in patients with normal sinus rhythm. Synonyms: N-Desmethyl Ivabradine D4 Hydrochloride; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]amino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-3-benzazepin-2-one-d4 Hydrochloride; N-Demethylivabradine-d4 Hydrochloride. Grade: 95% by HPLC; 98% atom D. Molecular formula: C26H30D4N2O5.HCl. Mole weight: 495.04. | |
| N-Desmethyl Ivabradine-[d6] Hydrochloride | N-Desmethyl Ivabradine-[d6] Hydrochloride is the labelled analogue of N-Desmethyl Ivabradine Hydrochloride, which is a metabolite of Ivabradine. Ivabradine can be used to treat chronic stable angina pectoris in patients with normal sinus rhythm. Synonyms: N-Desmethyl Ivabradine D6 Hydrochloride; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]amino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-3-benzazepin-2-one-d6 Hydrochloride; N-Demethylivabradine-d6 Hydrochloride. Grade: 98% by HPLC. CAS No. 1346600-74-5. Molecular formula: C26H29D6ClN2O5. Mole weight: 497.02. | |
| N-Desmethyl Loperamide-[d3] | N-Desmethyl Loperamide-[d3] is the labelled analogue of N-Desmethyl Loperamide, which is a metabolite of Loperamide. Loperamide is an improved PET radiotracer for imaging P-gp function. Uses: A labelled metabolite of loperamide; a new and improved pet radiotracer for imaging p-gp function. Synonyms: N-Desmethyl Loperamide D3. Grade: 95% atom D. CAS No. 1189488-17-2. Molecular formula: C28H28D3ClN2O2. Mole weight: 466.03. | |
| N-Desmethyl Mifepristone-[d3] | N-Desmethyl Mifepristone-[d3] is the labelled analogue of N-Demethyl Mifepristone, which is a metabolite of Mifepristone. Mifepristone is a medication used for medical abortion. Synonyms: N-Desmethyl Mifepristone D3; (11β,17β)-17-Hydroxy-11-[4-(methyl-d3-amino)phenyl]-17-(1-propyn-1-yl)-estra-4,9-dien-3-one; N-Desmethyl-RU 486-d3. Grade: > 95%. Molecular formula: C28H30D3NO2. Mole weight: 418.59. | |
| N-Desmethyl Nefopam-[d4] Hydrochloride | N-Desmethyl Nefopam-[d4] Hydrochloride is the labelled analogue of N-Desmethyl Nefopam Hydrochloride, which is an impurity of Nefopam. Nefopam is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake. Synonyms: N-Desmethyl Nefopam D4 Hydrochloride; N-Desmethylnefopam-D4 Hydrochloride; Nornefopam-D4 Hydrochloride. Grade: >95%. Molecular formula: C16H13D4NO.HCl. Mole weight: 279.80. | |
| N-Desmethyl Netupitant-[d6] | N-Desmethyl Netupitant-[d6] is the labelled analogue of N-Desmethyl Netupitant, which is a derivative of Netupitant. Netupitant is a selective neurokinin 1 receptor antagonist with potential antiemetic activity. Synonyms: N-Desmethyl Netupitant D6; N,α,α-Trimethyl-N-[4-(2-methylphenyl)-6-(1-piperazinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide-d6; 2-[3,5-Bis(trifluoromethyl)phenyl]-N-methyl-N-[6-(piperazin-1-yl)-4-o-tolylpyridin-3-yl]isobutyramide-d6. Grade: >98%. CAS No. 2070015-21-1. Molecular formula: C29H24D6F6N4O. Mole weight: 570.60. | |
| N-Desmethyl Prochlorperazine-[d8] Dimaleate | An isotope labelled metabolite of Prochlorperazine. Prochlorperazine is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents which are used for the antiemetic treatment of nausea and vertigo. Synonyms: 2-Chloro-10-[3-(1-piperazinyl)propyl]-phenothiazine-d8 Dimaleate. Grade: > 95%. CAS No. 1246817-68-4. Molecular formula: C27H22D8ClN3O8S. Mole weight: 600.11. | |
| N-Desmethyl Rosiglitazone-[d4] | A labelled impurity of Rosiglitazone. Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class. Synonyms: 5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione-d4; SB 237216-d4. Grade: > 95%. CAS No. 1215407-67-2. Molecular formula: C17H13N3O3SD4. Mole weight: 347.43. | |
| N-Desmethyl Rosuvastatin-[d6] Disodium Salt | N-Desmethyl Rosuvastatin-[d6] is the labelled analogue of N-Desmethyl Rosuvastatin. Rosuvastatin is an inhibitor of the enzyme HMG-CoA reductase in vitro. Synonyms: (E)-7-[4-(4-Fluorophenyl)-6-(isopropyl-d6)-2-mesylaminopyrimidin-5-yl]-(3R,5S)-dihydroxyhept-6-enoic Acid Disodium Salt. Molecular formula: C21H18D6FN3Na2O6S. Mole weight: 517.51. | |
| N-Desmethyl Tamoxifen-[d5] | An isotope labelled metabolite of Tamoxifen. Tamoxifen is a medication that is used to treat breast cancer. Synonyms: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 164365-16-6. Molecular formula: C25H22D5NO. Mole weight: 362.52. | |
| N-Desmethyl Verapamil-[d7] Hydrochloride | N-Desmethyl Verapamil-[d7] HCl is a labelled metabolite of Verapamil. Verapamil is a medication used for the treatment of high blood pressure, chest pain from not enough blood flow to the heart, and supraventricular tachycardia. Synonyms: Nor Verapamil-d7, Hydrochloride; α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)- benzeneacetonitrile-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1216413-74-9. Molecular formula: C26H29N2O4D7.HCl. Mole weight: 484.08. | |
| N-Desmethyl Zolmitriptan-[d3] | N-Desmethyl Zolmitriptan-[d3] is the labelled analogue of N-Desmethyl Zolmitriptan, which is a metabolite of Zolmitriptan. Synonyms: (4S)-4-[[3-[2-(Methyl-d3-amino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone; N-Desmethyl-d3 Zolmitriptan; N-Desmethyl Zolmitriptan-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1217623-11-4. Molecular formula: C15H16D3N3O2. Mole weight: 276.35. | |
| N-Despropyl Macitentan-[d4] | N-Despropyl Macitentan-[d4] is the labelled analogue of N-Despropyl Macitentan, which is an active metabolite of Macitentan. N-Despropyl-macitentan is part of the family of endothelin receptor antagonist that allows for treatment of pulmonary arterial hypertension (PAH). Synonyms: Macitentan ACT-132577 D4; N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-sulfamide-d4; N-Despropyl Macitentan-d4; Aprocitentan D4. Grade: 98% HPLC. Molecular formula: C16H10D4Br2N6O4S. Mole weight: 550.22. | |
| N-(Diphenylmethylidine)-3-(aminomethyl)pyridine-[2,4,5,6-d4] | N-(Diphenylmethylidine)-3-(aminomethyl)pyridine-[2,4,5,6-d4]. Synonyms: N-(Diphenylmethylene)-3-pyridine-2,4,5,6-d4-methanamine; N-(Diphenylmethylidine)-3-(aminomethyl)pyridine-2,4,5,6-D4. Grade: 95% atom D. CAS No. 1020719-40-7. Molecular formula: C19H12D4N2. Mole weight: 276.37. | |
| n-Docosane-[d46] | n-Docosane-[d46]. Synonyms: n-Docosane-d46. Grade: 98% atom D. CAS No. 260411-88-9. Molecular formula: C22D46. Mole weight: 356.89. | |
| (+)-Nebivolol | Dexnebivolol is an enantiomer of Nebivolol which is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and left ventricular failure in Europe. It is highly cardioselective under certain circumstances. Uses: Treatment of hypertension and left ventricular failure. Synonyms: R67138; R-67138; R 67138; Dexnebivolol; (S,R,R,R)-nebivolol; Bystolic; D-Nebivolol; (αR,α'R,2R,2'S)-α,α'-[IMinobis(Methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-Methanol]. Grade: 95%. CAS No. 118457-15-1. Molecular formula: C22H25F2NO4. Mole weight: 405.44. | |
| (±)-Nebivolol-d4 hydrochloride | (±)-Nebivolol-d4 is intended for use as an internal standard for the quantification of nebivolol by GC- or LC-MS. Nebivolol is a potent and selective β1-adrenergic receptor (β1-AR) antagonist (IC50s = 7.41 and 251 nM for β1- and β2-ARs, respectively, in a radioligand binding assay using rabbit lung membrane preparations). It is also selective for β1-ARs over serotonin 5-HT1A and 5-HT2, α1- and α2-adrenergic, histamine H1, and dopamine D2 receptors (IC50s = 27.5 and 2,239, 3,162 and >10,000, 5,623, and 10,000 nM, respectively). Nebivolol inhibits cAMP accumulation induced by norepinephrine in primary rat cardiac cells (IC50 = 22 nM) and induces vasodilation in mouse renal arteries via a nitric oxide- and cGMP-dependent mechanism (EC50 = 11.36 μM). It decreases contraction of isolated human left ventricular trabeculae induced by isoproterenol (IC50 = 7.0 μM) but does not exert intrinsic sympathomimetic activity (ISA). Nebivolol inhibits proliferation of human coronary artery smooth muscle cells (HCASMCs) in the presence and absence of growth factors (IC50s = 6.1, 6.8, 6.4, and 7.7 μM for HCASMCs grown in media containing no growth factor, PDGFBB, basic FGF, and TGF-β1, respectively). Formulations containing nebivolol have been used to treat hypertension. Synonyms: (S,R,R,R)-Nebivolol-d4 Hydrochloride; (1R)-2,2-dideuterio-2-[[(2R)-1,1-dideuterio-2-[(2S)-6-fluo | |
| Nebivolol hydrochloride | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.23 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1). Grade: > 95%. CAS No. 169293-50-9. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nefopam-[d3] | Nefopam-[d3] is the labelled analogue of Nefopam. Nefopam is a centrally acting, non-opioid analgesic drug that is primarily used to treat moderate to severe pain. Synonyms: Nefopam D3; 3,4,5,6-Tetrahydro-5-(methyl-d3)-1-phenyl-1H-2,5-benzoxazocine; (+/-)-Nefopam-d3; Fenazoxine-d3. Grade: >95%; ≥99% atom D. CAS No. 1346747-15-6. Molecular formula: C17H16D3NO. Mole weight: 256.37. | |
| Nefopam hydrochloride | Nefopam HCl is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.It is widely used, mainly in European countries, for the relief of moderate to severe pain as an alternative to opioid analgesic drugs. Uses: Analgesics, non-narcotic. Synonyms: Nefopam Hydrochloride. Grade: >98%. CAS No. 23327-57-3. Molecular formula: C17H19NO.HCl. Mole weight: 289.8. | |
| Nefopam N-Oxide-[d3] | Nefopam N-Oxide-[d3] is the labelled analogue of Nefopam N-Oxide, which is a metabolite of Nefopam. Synonyms: Nefopam-d3 N-Oxide; 3,4,5,6-Tetrahydro-5-(methyl-d3)-1-phenyl-1H-2,5-benzoxazocine 5-Oxide. Grade: >95%. CAS No. 1346603-50-6. Molecular formula: C17H16D3NO2. Mole weight: 272.36. | |
| Nelfinavir-[d3] | Nelfinavir-[d3] is the labelled analogue of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor. Synonyms: Nelfinavir D3; Viracept-d3; (3S-(2(2S*,3S*),3alpha,4abeta,8abeta))-N-(1,1-Dimethylethyl)decahydro-2-(2-hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-4-(phenylthio)butyl)-3-isoquinolinecarboxamide-d3. Grade: ≥96%; ≥98% atom D. CAS No. 1217629-70-3. Molecular formula: C32H42D3N3O4S. Mole weight: 570.80. | |
| Nemorubicin | Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. Uses: Adcs cytotoxin. Synonyms: Methoxymorpholinyldoxorubicin; PNU152243A; PNU-152243A; PNU 152243A; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-[(2S)-2-methoxymorpholin-4-yl]-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-; 3'-Deamino-3'-(2(S)-methoxy-4-morpholinyl)doxorubicin; Methoxymorpholino-doxorubicin. Grade: ≥97% by HPLC. CAS No. 108852-90-0. Molecular formula: C32H37NO13. Mole weight: 643.23. | |
| Nepafenac-[d5] | Nepafenac-[d5] is the labelled analogue of Nepafenac which is a COX-2 inhibitor and commonly used as an anti-inflammatory agent. Uses: The isotope labelled nepafenac. Synonyms: Nepafenac D5; 2-Amino-3-benzoylbenzeneacetamide-d5. Grade: 95% by HPLC; 95% atom D. CAS No. 1246814-53-8. Molecular formula: C15H9D5N2O2. Mole weight: 259.31. | |
| Nε-(1-Carboxymethyl)-L-lysine-[d4] | Nε-(1-Carboxymethyl)-L-lysine-[d4]. Synonyms: 2-Amino-6-(carboxymethylamino)hexanoic Acid-d4; N6-(Carboxymethyl)lysine-d4; N6-(Carboxymethyl)-L-lysine-d4; CML-d4; Nε-(1-Carboxymethyl)-L-lysine-d4; Nε-carboxymethyl-L-Lysine-4,4,5,5-d4. Grade: ≥96%; ≥97% atom D. CAS No. 936233-18-0. Molecular formula: C8H12D4N2O4. Mole weight: 208.25. | |
| Nepsilon,Nepsilon,Nepsilon-Trimethyl-[13C3]-L-lysine hydrochloride | Nepsilon,Nepsilon,Nepsilon-Trimethyl-[13C3]-L-lysine hydrochloride is an isotopic labelled derivative of L-lysine. L-Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine. It is also used in the labelling of human bone marrow mesenchymal stem cells for analysis. Synonyms: Nepsilon,Nepsilon,Nepsilon-Trimethyl-13C3-L-lysine hydrochloride; Nε,Nε,Nε-Trimethyl-13C3-L-lysine hydrochloride. Grade: 97% by HPLC; 99% atom 13C. Molecular formula: C6[13C]3H20N2O2.HCl. Mole weight: 227.71. | |
| Nequinate-[d7] | Nequinate-[d7] is the labelled analogue of Nequinate, which is a medication used for the treatment of coccidiosis. It is only approved for veterinary use in some countries. Synonyms: Nequinate-D7; Methyl 6-Butyl-4-oxo-7-((phenyl-d5)methoxy-d2)-1,4-dihydroquinoline-3-carboxylate; 7-Benzyloxy-D7-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methyl ester; Methyl benzoquate-d7; Statil-d7; Statoquate-d7; Statyl-d7; Tranil-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1584701-10-9. Molecular formula: C22H16D7NO4. Mole weight: 372.47. | |
| N-Ethyl-[d5]-maleimide | N-Ethyl-[d5]-maleimide is the labelled analogue of N-ethylmaleimide. N-Ethylmaleimide (NEM) is a derivative of maleic acid and is used as a reagent for alkylation and covalent modification of nucleophilic thiol residues on proteins. It acts as an irreversible inhibitor of all cysteine peptidases that alkylates the active site thiol group of the enzymes. Synonyms: N-Ethylmaleimide (Ethyl-D5); 1-Ethyl-1H-pyrrole-2,5-dione-d5; Ethylmaleimide-d5; Maleic Acid N-Ethylimide-d5; NEM-d5; NSC 7638-d5; N-Ethyl Maleimide-d5; NEM (ethyl-d5). Grade: 98% by CP; 98% atom D. CAS No. 360768-37-2. Molecular formula: C6H2D5NO2. Mole weight: 130.16. | |
| Netupitant-[d6] | Netupitant-[d6] is the labelled analogue of Netupitant, which is a selective neurokinin 1 receptor antagonist with potential antiemetic activity. Synonyms: Netupitant D6. Grade: 98% by HPLC; 98% atom D. CAS No. 2070015-31-3. Molecular formula: C30H26D6F6N4O. Mole weight: 584.63. | |
| Netupitant N-oxide-[d6] | Netupitant N-oxide-[d6] is the labelled analogue of Netupitant N-oxide, which is a derivative of Netupitant. Netupitant is a selective neurokinin 1 receptor antagonist with potential antiemetic activity. Synonyms: Netupitant N-oxide D6; N,α,α-Trimethyl-N-[6-(4-methyl-4-oxido-1-piperazinyl)-4-(2-methylphenyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide-d6. Grade: 98% by HPLC. CAS No. 2070015-12-0. Molecular formula: C30H26D6F6N4O2. Mole weight: 600.64. | |
| NeupNAcα2,3[UL-13C6]Galpβ1,3GalpNAc sodium salt | NeupNAcα2,3[UL-13C6]Galpβ1,3GalpNAc sodium salt. Synonyms: N-acetyl-neuraminic acid(alpha2-3)[UL-13C6]galactose(beta1-3)N-acetyl-galactosamine; a-NeuNAc-(2-3)-b-D-[UL-13C6]Gal-(1-3)-D-GalNAc sodium salt; NeuNAc(a2-3)[U-13C6]Gal(b3)GalNAc sodium salt; NeupNAcα2,3[UL-13C6]Galpβ1,3GalpNAc sodium salt; ST-[13C6gal]antigen. Molecular formula: C19[13C]6H41N2NaO19. Mole weight: 702.54. | |
| Nevirapine | Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. Synonyms: BI-RG-587; BIRG 0587; BIRG587; HSDB 7164; Nevirapine; NSC 641530; NVP; Brand name: Viramune Viramune XR. Grade: >98%. CAS No. 129618-40-2. Molecular formula: C15H14N4O. Mole weight: 266.3. | |
| Nevirapine-[d3] | Nevirapine-[d3] is the labelled analogue of Nevirapine. Nevirapine is an anti-HIV drug that reduces the amount of virus in the body. Uses: Labelled nevirapine (n391275), a potent (ic50=84nm) and selective non-nucleoside inhibitor of hiv-1 reverse transcriptase. antiviral. Synonyms: Nevirapine D3. Grade: 95% atom D. CAS No. 1051419-24-9. Molecular formula: C15H11D3N4O. Mole weight: 269.32. | |
| Nevirapine-[d4] | Nevirapine-[d4] is the labelled analogue of Nevirapine, which is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. Synonyms: Nevirapine D4; 11-cyclopropyl-2,2,3,3-d4-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one. Grade: 95% by HPLC; 95% atom D. CAS No. 1051418-95-1. Molecular formula: C15H10D4N4O. Mole weight: 270.33. | |
| Nevirapine-[d5] | Nevirapine-[d5] is the labelled analogue of Nevirapine, which is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. Synonyms: Nevirapine D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1189717-29-0. Molecular formula: C15H9D5N4O. Mole weight: 271.33. | |
| NG,NG-Dimethyl-[d6]-L-arginine dihydrochloride | NG,NG-Dimethyl-[d6]-L-arginine dihydrochloride is a labelled NG,NG-Dimethyl-L-arginine dihydrochloride, which is an endogenous nitric oxide synthase inhibitor. Synonyms: asym-Dimethyl-d6-arginine; ADMA-d6. Grade: 95% by HPLC; 99% atom D. Molecular formula: C8D6H14Cl2N4O2. Mole weight: 281.21. | |
| NG,NG'-Dimethyl-L-arginine-[d6] | NG,NG'-Dimethyl-L-arginine-[d6] is the labelled analogue of NG,NG'-Dimethyl-L-arginine, which is a potential endogenous nitric oxide inhibitor. Synonyms: NG,NG'-Dimethyl-L-arginine-d6; N5-[(Dimethylamino)iminomethyl]-L-ornithine-d6; N5-[Bis(methylamino)methylene]-L-ornithine-d6; SDMA-d6; N,N'-Dimethylarginine-d6; N(G1),N(G2)-Dimethylarginine-d6; N3,N4-Dimethylarginine-d6. Grade: 96%; ≥99% atom D. CAS No. 1331888-08-4. Molecular formula: C8H12D6N4O2. Mole weight: 208.29. | |
| n-Heneicosane-[d44] | n-Heneicosane-[d44]. Synonyms: n-Heneicosane-D44. Grade: 99% atom D. CAS No. 39756-37-1. Molecular formula: C21D44. Mole weight: 340.85. | |
| n-Heptadecane-[d36] | n-Heptadecane-[d36]. Synonyms: n-Heptadecane-D36. Grade: 95% atom D. CAS No. 39756-35-9. Molecular formula: C17D36. Mole weight: 276.69. | |
| n-Hexacosane-[d54] | n-Hexacosane-[d54]. Synonyms: n-Hexacosane-d54. Grade: 98% atom D. CAS No. 1219803-91-4. Molecular formula: C26D54. Mole weight: 421.04. | |
| N-Hexadecanol-[d31] | N-Hexadecanol-[d31]. Synonyms: 1-Hexadecan-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d31-ol; N-Hexadecanol-D31; n-Hexadecyl Alcohol-d31; hexadecan-1-ol-d4-d31; Cetyl acrylate-d4-d31; Acrylsaeure-hexadecyl ester-d31; Hexadecyl acrylate-d31; cetyle alcohol-d31; Palmityl acrylate-d31; palmityl alcohol-d31; n-hexadecyl acrylate-d31. Grade: 98%; 98% atom D. CAS No. 203633-15-2. Molecular formula: C16H3D31O. Mole weight: 273.63. | |
| N-Hexanoylglycine-[2,2-d2] | N-Hexanoylglycine-[2,2-d2] is a labelled N-Hexanoylglycine. Hexanoylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. Hexanoylglycine is commonly found in urine of patients with hereditary medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. Synonyms: N-n-Caproylglycine-d2; Hexanoylaminoacetic Acid-d2. Grade: 95% by HPLC; 98% atom D. CAS No. 1256842-52-0. Molecular formula: C8H13D2NO3. Mole weight: 175.22. | |
| Nicarbazin-[d8] | Nicarbazin-[d8] is a labelled form of Nicarbazin, an anti-parasitic drug for veterinary use. Synonyms: Nicarbazin-d8; 1,3-Bis(4-nitrophenyl)urea-d8 4,6-Dimethyl-2(1H)-pyrimidinone. Grade: > 95%. Molecular formula: C13H2D8N4O5.C6H8N2O. Mole weight: 434.43. | |
| Niclosamide-[13C6] | Niclosamide-[13C6] is the labelled analogue of Niclosamide, which is used as an anthelmintic drug. Synonyms: Niclosamide-13C6; 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide-13C6; 2',5-Dichloro-4'-nitrosalicylanilide-13C6; Bayluscid-13C6; Cestocid-13C6; Cestocide-13C6; Devermin-13C6; Devermine-13C6; Helmiantin-13C6; Iomesan-13C6; Lintex-13C6; Mansonil-13C6; Mato-13C6; N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide-13C6; Yomesan-13C6; Zestocarp-13C6. Grade: >95%. CAS No. 1325808-64-7. Molecular formula: C7[13C]6H8Cl2N2O4. Mole weight: 333.08. | |
| Niclosamide-[13C6] hydrate | Niclosamide-[13C6] hydrate is the labelled analogue of Niclosamide hydrate, which is used for the treatment of most tapeworm infections by inhibiting DNA replication. Synonyms: Niclosamide-13C6 hydrate; Niclosamide Monohydrate-13C6; 2',5-Dichloro-4'-nitrosalicylanilide monohydrate-13C6. Grade: > 95%. CAS No. 1325559-12-3. Molecular formula: C7[13C]6H8Cl2N2O4.H2O. Mole weight: 351.09. | |
| Nicorandil | Nicorandil is potassium channel activator. Synonyms: Antagonil. Grade: >98%. CAS No. 65141-46-0. Molecular formula: C8H9N3O4. Mole weight: 211.17. | |
| Nicorandil-[d4] | Nicorandil-[d4] is the labelled analogue of Nicorandil, which is a potassium channel activator. Synonyms: Nicorandil D4; N-[2-(Nitrooxy)ethyl]-3-pyridinecarboxamide-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1132681-23-2. Molecular formula: C8H5D4N3O4. Mole weight: 215.19. | |
| Nicosulfuron-[d6] | Nicosulfuron-[d6] is the labelled analogue of Nicosulfuron, which is a post-emergence sulfonylurea herbicide. Uses: Post-emergence sulfonylurea herbicide. Synonyms: Nicosulfuron-d6. Grade: 99% atom D. CAS No. 1189419-41-7. Molecular formula: C15H12D6N6O6S. Mole weight: 416.44. | |
| Nicotinamide-[d4] | Nicotinamide-[d4] is the labelled analogue of Nicotinamide. Nicotinamide, a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also acts as an activator of sirtuins. Synonyms: 3-Pyridinecarboxamide-d4; 3-(Aminocarbonyl)pyridine-d4; 3-Amidopyridine-d4; 3-Carbamoylpyridine-d4; 3-Pyridinecarboxylic acid amide-d4; Aminicotin-d4; Benicot-d4; Nicosylamide-d4; Nicotinic Acid Amide-d4; Vitamin B3-d4. Grade: 98% by CP; 98% atom D. CAS No. 347841-88-7. Molecular formula: C6H2D4N2O. Mole weight: 126.15. | |
| Nicotinamide N-Oxide-[d4] | Nicotinamide N-Oxide-[d4] is the labelled analogue of Nicotinamide N-Oxide, which is a metabolite of Nicotinamide. Synonyms: Nicotinamide-d4 N-Oxide; 1-Oxide 3-Pyridinecarboxamide-d4; Nicotinamide-d4 1-Oxide; NSC 168416-d4; NSC 30531-d4; Niacinamide-d4 N-Oxide; Pyridine-3-carboxamide-d4 1-Oxide. Grade: 98%. CAS No. 1246817-64-0. Molecular formula: C6H2D4N2O2. Mole weight: 142.15. | |
| Nicotine 1'-N-oxide | A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Synonyms: (1'S,2'S)-trans-Nicotine 1'-Oxide; 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]pyridine; (1S-cis)-3-(1-Methyl-2-pyrrolidinyl)pyridine N-Oxide; (1S,2S)-syn-Nicotine N'-oxide; (1'S,2'S)-trans-Nicotine-1'-N-oxide; 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl] pyridine. Grade: > 95%. CAS No. 51095-86-4. Molecular formula: C10H14N2O. Mole weight: 178.24. | |
| (±)-Nicotine-D3 salicylate | (±)-Nicotine-D3 salicylate is a labelled isomer salt of nicotine, which is a potent parasympathomimetic stimulant. Synonyms: 1-(Methyl-D3)-2-(3-pyridyl)-pyrrolidine salicylate salt. Grade: 95% by HPLC; 98% atom D. CAS No. 1173021-00-5. Molecular formula: C17H17D3N2O3. Mole weight: 303.37. | |
| Nicotine hemisulfate | Nicotine hemisulfate is a typical nicotinic acetylcholine receptor agonist. Synonyms: Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, sulfate (2:1); Nicotine, sulfate (2:1); Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, sulfate (2:1); Nicotine sulfate; 3-[(2S)-1-Methyl-2-pyrrolidinyl]pyridine Sulfate; Black Leaf 40; (-)-1-Methyl-2-(3-pyridyl)pyrrolidine Sulfate. Grade: ≥95%. CAS No. 65-30-5. Molecular formula: C10H14N2.1/2H2O4S. Mole weight: 422.54. | |
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