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Cytidine 5'-triphosphate tetrasodium salt
Cytidine 5'-triphosphate tetrasodium salt is a vital constituent, finding extensive utility in RNA molecule research and development. Its role as a substrate for reverse transcription from RNA to cDNA is indispensable for diverse research undertakings, encompassing gene expression investigations, PCR amplification and sequencing. Alternative Names: Cytidine 5'-(tetrahydrogen triphosphate), tetrasodium salt; CTP-Na4; Cytidine Triphosphate tetrasodium Salt; CTP tetrasodium Salt. Grades: 95%. CAS No. 93688-66-5. Molecular formula: C9H12N3Na4O14P3. Mole weight: 571.08.
Cytidine 5'-triphosphate trisodium salt
Cytidine 5'-triphosphate is a pyrimidine nucleoside triphosphate that is used in the synthesis of RNA by RNA polymerases. It can participate in a variety of biochemical reactions. Alternative Names: CTP-Na3; Cytidine Triphosphate trisodium Salt; Cytidine 5'-(Tetrahydrogen triphosphate) trisodium Salt; CTP trisodium Salt. CAS No. 54619-78-2. Molecular formula: C9H13N3Na3O14P3. Mole weight: 549.10.
Cytidylyl-(3'-5')-cytidine
Cytidylyl-(3'-5')-cytidine is a biochemical utilized in the production of RNA. It also plays a crucial role in signaling pathways. In the biomedical field, it is being researched as a potential treatment for certain cancers, such as pancreatic cancer. Alternative Names: CpC RNA Dinucleotide (5'-3'); CmpC; 3'-Cytidylic acid, 5'-ester with cytidine; Cytidylyl-(3'→5')-cytidine; CpC; NSC 131650; NSC 91550. Grades: ≥95% by AX-HPLC. CAS No. 2536-99-4. Molecular formula: C18H25N6O12P. Mole weight: 548.40.
Cytochalasin D, BODIPY TMR Conjugate
Cytochalasin D, BODIPY TMR Conjugate is an orange-fluorescent derivative of cytochalasin D, an inhibitor of actin polymerization. This probe has been used for labeling actin filaments in live cells. It is relatively insensitive to environment and pH changes. Alternative Names: Cytochalasin D, EverFluor TMR Conjugate. Molecular formula: C51H56BF2N3O3. Mole weight: 887.81.
Cytochrome C
Cytochrome C. Alternative Names: HUMAN CYTOCHROME C; CYT-C; CYTOCHROME C; CYTOCHROME C, ACID MODIFIED; CYTOCHROME C, BOVINE; CYTOCHROME C (BOVINE HEART); CYTOCHROME C PEPTIDE MAP CONTROL; CYTOCHROME C EQUINE HEART. Grades: Iron content >0.43% ( 85% as based on Mol. Wt. 12,588). CAS No. 9007-43-6. Molecular formula: C42H54FeN8O6S2. Mole weight: 886.9.
Cytosine
Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (anamine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. Alternative Names: Cytarabine Impurity C; 4-Aminopyrimidin-2(1H)-one; 6-Amino-2(1H)-pyrimidinone; 4-Amino-1H-pyrimidin-2-one; 4-Amino-2(1H)-pyrimidinone; 4-Amino-2-hydroxypyrimidine; 4-Aminouracil; Gemcitabine EP Impurity A; Lamivudine EP Impurity E; 2-Hydroxy-4-pyrimidinamine; 4-Amino-2-oxo-1,2-dihydropyrimidine; Cytosines; Cytosinimine; NSC 27787; Cytarabine EP Impurity C; Gemcitabine hydrochloride EP Impurity A. Grades: 98%. CAS No. 71-30-7. Molecular formula: C4H5N3O. Mole weight: 111.10.
D-[1-13C]Galacturonic acid potassium salt
D-[1-13C]Galacturonic acid potassium salt.
D-(-)-2-Phenylglycine
D-(-)-2-Phenylglycine is the derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. It is also an impurity of Ampicillin and Cefaclor. Alternative Names: Ampicillin EP Impurity L; Cefaclor EP Impurity A; (-)-(R)-Phenylglycine; (-)-Phenylglycine; (2R)-Amino-2-phenylethanoic Acid; (R)-(-)-2-Phenylglycine; (R)-2-Amino-2-phenylacetic Acid; (R)-2-Amino-2-phenylethanoic Acid; (R)-2-Phenyl-2-aminoethanoic Acid; (R)-2-Phenylglycine; (R)-2-Phenylglycine. Grades: ≥ 99% (Assay). CAS No. 875-74-1. Molecular formula: C8H9NO2. Mole weight: 151.17.
D-(-)-3-Phosphoglyceric Acid Disodium Salt serves as a pivotal component within the biomedical sector, acting as a fundamental substrate essential for conducting enzymatic assays that gauge the performance of phosphoglycerate kinase and associated inhibitors. Furthermore, its significance extends to the examination of glycolysis mechanisms and the Calvin cycle within plant cellular structures. Alternative Names: Sodium (R)-2-Carboxy-2-Hydroxyethyl Phosphate. Grades: 93%. CAS No. 80731-10-8. Molecular formula: C3H5Na2O7P. Mole weight: 230.02.
d5SICS
d5SICS is a remarkable fluorescent nucleotide analog, harnessed extensively in the realm of DNA sequencing and molecular biology analysis. Exuding its profound impact, this exquisite compound profoundly stimulates DNA polymerase activity and remarkably enhances sequencing accuracy, heralding its excellence in facilitating DNA sequencing, mutation detection and genotyping analysis. Grades: ≥ 97%. CAS No. 1010689-00-5. Molecular formula: C16H17NO3S. Mole weight: 291.37.
DAB-Am-4 unveils its prowess as a Polypropylenimine tetramine dendrimer belonging to generation 1. Its exceptional utility triumphs in battling a multitude of afflictions. The enchantment of this innovation lies within its triumphant foray into the domains of drug delivery systems, gene therapy, and diagnostics. Within the intricate tapestry of its chemical composition and structure, lies the key to unlocking the potential of targeted drug dispatch and reinforcing the therapeutic efficacy against formidable maladies. Alternative Names: N,N,N,N-Tetrakis(3-aminopropyl)-1,4-butanediamine. Grades: 95%. CAS No. 120239-63-6. Molecular formula: C16H40N6. Mole weight: 316.53.
Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Uses: Benzimidazoles; beta-alanine / analogs & derivatives. Alternative Names: BIBR 953; BIBR953; BIBR-953. Grades: >98%. CAS No. 211914-51-1. Molecular formula: C25H25N7O3. Mole weight: 471.51.
Dabigatran etexilate mesylate
Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. It is a reversible and selective, direct thrombin inhibitor (DTI). Alternative Names: Ethyl 3-(((2-(((4-(((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1h-benzimidazol-5-yl)carbonyl)(pyridin-2-yl)amino)propanoate, methanesulfonate; Dabigatran etexilate mesylate; BIBR 1048MS; BIBR1048MS; BIBR-1048MS; BIBR 1048; BIBR1048; BIBR-1048; band name: Pradaxa. Grades: >98%. CAS No. 872728-81-9. Molecular formula: C35H45N7O8S. Mole weight: 723.84.
dA(Bz)-PACE Phosphoramidite
dA-PACE Phosphoramidite is a crucial reagent utilized in the development of oligonucleotide therapeutics for treating various genetic disorders such as cystic fibrosis and Huntington's disease. The unique PACE (phosphoramidite conjugated to aminohexylCE) modification improves the pharmacokinetic properties of the resulting oligonucleotide drugs, allowing for enhanced cellular uptake and longer half-life in the body. Alternative Names: dA-PACE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; DNA A(Bz) PACE amidite. Grades: ≥95%. CAS No. 411234-24-7. Molecular formula: C51H58N7O8P. Mole weight: 928.02.
Daclatasvir
Daclatasvir, inhibits the HCV protein NS5A, and thus can be used as a drug candidate for the treatment of hepatitis C (HCV). Alternative Names: Daclatasvir; BMS-790052; BMS 790052; BMS790052; EBP-883; EBP 883; EBP883; trade name Daklinza. Grades: 0.98. CAS No. 1009119-64-5. Molecular formula: C40H50N8O6. Mole weight: 738.89.
Dacuronium bromide
Dacuronium bromide. Alternative Names: [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-hydroxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]acetate;dibromide;DacuroniumBromide;UNII-33482245B6;27115-86-2;SCHEMBL2734609. Grades: 95%. CAS No. 27115-86-2. Molecular formula: C33H58N2O3Br2. Mole weight: 690.633.
DAF-2 diacetate
DAF-2 diacetate is a cell-permeable fluorescent indicator for the detection of nitric oxide (NO). Uses: Useful in affinity chromatography and as an inhibitor of coa-requiring enzymes in metabolic studies.cell permeable fluorescent detector of nitric oxide in living cells. 4,5-diaminofluorescein diacetate (daf-2 da) has been used as a fluorescent dye for no (nitric oxide) detection. Alternative Names: DAF-2 DA; 4,5-Diaminofluorescein diacetate; 2-(3,6-diacetyloxy-4,5-diamino-9H-xanthen-9-yl)-benzoic acid. Grades: ≥95%. CAS No. 205391-02-2. Molecular formula: C24H18N2O7. Mole weight: 446.4.
DAF-FM DA
DAF-FM DA is a cell-permeable and fluorescent nitric oxide (NO) indicator. It is deacetylated by intracellular esterases to become DAF-FM when exposed to oxygen and NO. Alternative Names: 4-Amino-5-methylamino-2',7'-difluorofluorescein diacetate; DAF-FM Diacetate; 3',6'-bis(acetyloxy)-4-amino-2',7'-difluoro-5-(methylamino)-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one. Grades: ≥98%. CAS No. 254109-22-3. Molecular formula: C25H18F2N2O7. Mole weight: 496.4.
Dalapon-methyl
Dalapon-methyl. Alternative Names: Dalapon-methyl, Methyl 2,2-dichloropropionate. CAS No. 17640-02-7. Molecular formula: C4H6Cl2O2. Mole weight: 157.00.
D-Allulose (D-Psicose)
A C3 epimer of L-Fructose. Alternative Names: D-Allulose; D-Ribo-2-hexulose. Grades: > 95%. CAS No. 551-68-8. Molecular formula: C6H12O6. Mole weight: 180.16.
D-alpha-Tocopherol Succinate
D-alpha-Tocopherol Succinate is the salt form of vitamin E, a class of eight fat-soluble compounds. It was shown to induce apoptosis and inhibit proliferation, and down-regulate the fibroblast growth factor receptor-1 (FGFR1). Vitamin supplement in health care products. Uses: Ingredient of health care products. Alternative Names: Vitamin E succinate; Alpha-Tocopheryl succinate; D-; 4-oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid. Grades: 95%. CAS No. 4345-3-3. Molecular formula: C33H54O5. Mole weight: 530.79.
damascenone
Damascenone is a fragrance natural compound known to possess anti-inflammatory properties and utilized in the development of drugs targeting inflammatory conditions such as arthritand asthma. Damascenone also exhibits potential in the research of neurodegenerative disorders like Alzheimer's disease. Alternative Names: beta-Damascenone; 1-(2,6,6-Trimethyl-1,3-cyclohexadien-1-yl)-2-buten-1-one; 2-Buten-1-one, 1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-; Damascenone; Damascenone (natural); EINECS 245-833-2; FEMA No. 3420; 4-(2,6,6-Trimethylcyclohexa-1,3-dienyl)but-2-en-4-one; 1-(2,6,6-trimethyl-1-cyclohexa-1,3-dienyl)but-2-en-1-one. Grades: >98%. CAS No. 23696-85-7. Molecular formula: C13H18O. Mole weight: 190.28.
Damulin A is found in the roots of Panax ginseng. Grades: > 95%. CAS No. 1202868-74-3. Molecular formula: C42H70O13. Mole weight: 782.99.
Dandelion Extract
Dandelion Extract is obtained from the whole above-ground part of dandelion, a compositae plant. The main active ingredient is flavonoid. It has a good skin care effect and will not cause skin aging and damage. It is a safe and effective plant-derived cosmetic raw material. Alternative Names: TARAXACUM OFFICINALE (DANDELION) EXTRACT; Dandelion extract; Dandelion Root Extract; Unii-L9D1817A42. Grades: 10:1. CAS No. 84775-55-3.
Danicopan
Danicopan is a potent, selective and orally active factor D inhibitor. Therapeutic FD inhibition was designed to control IVH and prevent C3-mediated extravascular hemolysis (EVH). Alternative Names: ACH-0144471; ACH-CFDIS; ALXN 2040; ACH-4471. CAS No. 1903768-17-1. Molecular formula: C26H23BrFN7O3. Mole weight: 580.41.
Danshensu
Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhibits platelet adhesion and aggregation. It also protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation. It increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. It may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. It significantly decreased the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size in vitro. It also had ROS scavenging activity and boosted endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which was mediated by Akt and ERK1/2 in western blot analysis. It significantly lowered tHcy in rats with elevated tHcy. Danshensu is a natural compound, which can also be used in cosmetics material. Alternative Names: Danshensu;76822-21-4;Salvianic acid A;(R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropanoic acid;Dan shen suan A;Salianic acid A;(2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid;UNII-4GF33A5PAJ;DS-182;4GF33A5PAJ;Benzenepropanoic acid, alpha,3,4-trihydroxy-, (alphaR)-;CHEMBL4218391;DT
Dansyl Alkyne
Dansyl Alkyne, a potent fluorescent reagent, is meticulously utilized in intricate bioconjugation reactions to precisely label biomolecules. Its versatility shines through in drug discovery endeavors, adding a touch of finesse as a probing tool for in-depth examination of complex biological processes. Boasting a myriad of applications, it proves indispensable in the realm of biomedical visualization and detection. Molecular formula: C15H16N2O2S. Mole weight: 288.36.
Dansyl Chloride
Dansyl Chloride is used for fluorescent labelling of amines, amino acids and proteins. Alternative Names: 5-(dimethylamino)-1-naphthalenesulfonyl chloride; 5-(dimethylamino)naphthalene-1-sulfonyl chloride. CAS No. 605-65-2. Molecular formula: C12H12ClNO2S. Mole weight: 269.75.
Dansyl-(D)phenylalanine. Uses: Used for the preparation of n-sulfonylamino acid derivatives as metalloproteinase inhibitors. Alternative Names: N-[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]-D-phenylalanine; D-Dansylphenylalanine; Dansyl-(R)-phenylalanine; Dansyl-D-Phe; Dansyl-D-phenylalanine; N-Dansyl-D-phenylalanine. Grades: 95%. CAS No. 56176-31-9. Molecular formula: C21H22N2O4S. Mole weight: 398.481.
DANSYL Fluoride
DANSYL Fluoride is a fluorescent serine probe that acts as an inhibitor of serine-type proteases. Alternative Names: DNSF. CAS No. 34523-28-9. Molecular formula: C12H12FNO2S. Mole weight: 253.30.
Dansyl sarcosine piperidinium salt, a chemical compound utilized in biochemical research, holds a pivotal position in the study of NMDA receptors. Owing to its proficiency in fluorescence detection of glutamate or glycine binding sites on these receptors, it may have the potential to augment the therapeutic treatment of prevalent neurological disorders such as Alzheimer's and Parkinson's. Its multifaceted uses offer researchers the versatility to investigate a host of biological phenomena related to the aforementioned conditions. Alternative Names: Dansylsarcosine piperidinium salt; Piperidin-1-ium 2-(5-(dimethylamino)-N-methylnaphthalene-1-sulfonamido)acetate. Grades: ≥95%. CAS No. 72517-44-3. Molecular formula: C20H29N3O4S. Mole weight: 407.53.
Dantrolene Sodium
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It suppresses the release of calcium previously sequestered by skeletal, but not cardiac, muscle sarcoplasmic reticulum. Alternative Names: Dantrolene sodium salt; Dantrium; Sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate. Grades: 98.0%~102.0%. CAS No. 14663-23-1. Molecular formula: C14H9N4NaO5. Mole weight: 336.239.
Danuglipron
Danuglipron is an orally small-molecule glucagon-like peptide 1 receptor (GLP-1R) agonist. Danuglipron is undergoing clinical trials for the treatment of diabetes. Alternative Names: PF-06882961; PF 06882961; PF06882961. Grades: 98% by HPLC. CAS No. 2230198-02-2. Molecular formula: C31H30FN5O4. Mole weight: 555.6.
Danuglipron tromethamine
PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). Alternative Names: PF-06882961 tromethamine; PF-06882961 Tris; Danuglipron Tris; 2-((4-(6-(4-cyano-2-fluorobenzyloxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-((2S)-oxetan-2-ylmethyl)-1H-benzimidazole-6-carboxylic acid, (1:1) salt with 2-amino-2-(hydroxymethyl)propane-1,3-diol. CAS No. 2230198-03-3. Molecular formula: C35H41FN6O7. Mole weight: 676.75.
Dapagliflozin
Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; BMS 512148. Grades: >98%. CAS No. 461432-26-8. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin 3-O-β-D-Glucuronide
Dapagliflozin 3-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-, (1S)-; (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; Dapagliflozin M-15 metabolite; Dapagliflozin 3-O-glucuronide. Grades: ≥95%. CAS No. 1351438-75-9. Molecular formula: C27H33ClO12. Mole weight: 585.00.
Dapagliflozin Impurity 16
Dapagliflozin Impurity 16 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: 1α-Methyl Dapagliflozin; Dapagliflozin Methoxy Pyranose Impurity; (2S,3R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methyl 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-; Methoxy Dapagliflozin. Grades: >95%. CAS No. 714269-57-5. Molecular formula: C22H27ClO7. Mole weight: 438.90.
Dapagliflozin Impurity 2
Dapagliflozin Impurity 2 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: 4-bromo-1-chloro-2-(2-ethoxybenzyl)benzene. Grades: >95%. CAS No. 1830346-16-1. Molecular formula: C15H14BrClO. Mole weight: 325.63.
Dapagliflozin Impurity 24
Dapagliflozin Impurity 24 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol; BMS-639432. Grades: >95%. CAS No. 1204222-85-4. Molecular formula: C21H25ClO7. Mole weight: 424.87.
Dapagliflozin Keto Impurity
Dapagliflozin Keto Impurity is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (2-Chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-ethoxyphenyl)methanone. Grades: >90%. CAS No. 2169998-23-4. Molecular formula: C21H23ClO7. Mole weight: 422.86.
Dapagliflozin Ortho Isomer
Dapagliflozin Ortho Isomer is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: CS-0165472. Grades: 95%. CAS No. 2040305-05-1. Molecular formula: C21H25ClO6. Mole weight: 408.87.
Dapagliflozin propanediol hydrate
Dapagliflozin (2S)-1,2-propanediol, hydrate is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Alternative Names: Dapagliflozin (2S)-1,2-propanediol, hydrate; Dapagliflozin propylene glycol hydrate; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1); D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate; Dapagliflozin (S)-propylene glycol hydrate; Dapagliflozin propanediol monohydrate; Edistride; Farxiga; Forxiga; (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (S)-propane-1,2-diol (1:1) monohydrate. Grades: >98%. CAS No. 960404-48-2. Molecular formula: C24H35ClO9. Mole weight: 502.98.
Dapagliflozin Tetraacetate
Dapagliflozin Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. Grades: > 98 %. CAS No. 461432-25-7. Molecular formula: C29H33ClO10. Mole weight: 577.02.
Dapagliflozin USP Related Compound A
Dapagliflozin Impurity 3 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Alternative Names: USP Dapagliflozin Related Compound A; (2S,3R,4R,5S,6R)-2-[4-Bromo-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Dapagliflozin Impurity 3; 4-Deschloro-4-bromo Dapagliflozin; Dapagliflozin 4-bromo Impurity; (1S)-1,5-Anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-. Grades: >95%. CAS No. 1807632-95-6. Molecular formula: C21H25BrO6. Mole weight: 453.32.
DAPI dihydrochloride
DAPI is a fluorescent DNA stain that binds to the minor groove of double-stranded DNA with preference for adenine and thymine (AT) rich DNA. DAPI is commonly used in microscopy and flow cytometry. It can be used on either fixed or live cells, although it crosses membranes in live cells less efficiently and demands higher concentrations to be used. Uses: Suitable for dna staining in agarose gels, analysis of changes in dna during apoptosis, detection of mycoplasma, photofootprinting of dna, immunofluorescent staining of cells. Alternative Names: DAPI;2-[4-(aminoiminomethyl)phenyl]-1H-indole-6-carboximidamide dihydrochloride. Grades: ≥90%. CAS No. 28718-90-3. Molecular formula: C16H15N5·2HCl. Mole weight: 350.3.
Dapiglutide
Dapiglutide is a long-acting dual agonist of glucagon-like peptide-1 receptor 1R (GLP-1R) / Glucagon-like peptide-2 receptor (GLP-2R) for the study of short bowel syndrome (SBS). Alternative Names: ZP7570. CAS No. 2296814-85-0. Molecular formula: C192H302N46O57. Mole weight: 4166.79.
dApNHpp
dApNHpp is a multifaceted biochemical compound reigning in the biomedical industry, standing as an eminent fluorescent probe. It can unveil the enigmatic realms of adenosine triphosphate (ATP) levels within living cells. This prodigious entity bestows illumination upon ATP-associated maladies like cancer, neurodegenerative disorders and metabolic syndromes. Alternative Names: (dAMPNPP); 2'-Deoxyadenosine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 753429-25-3. Molecular formula: C10H17N6O11P3 (free acid). Mole weight: 490.19 (free acid).
Dapoxetine hydrochloride
Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor. Alternative Names: LY-210448; LY 210448; LY210448. Grades: >98%. CAS No. 129938-20-1. Molecular formula: C21H23NO.HCl. Mole weight: 341.87.
DAPT
DAPT, also called γ-Secretase Inhibitor IX, is a potent and selective inhibitor of γ-secretase which leads to a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human)). Uses: Differentiation. Alternative Names: tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAP. Grades: 0.98. CAS No. 208255-80-5. Molecular formula: C23H26F2N2O4. Mole weight: 432.46.
D-Arabinose-5-phosphate disodium salt is a biomedically utilized compound, exhibiting promising attributes in the research of malignant neoplasms and metabolic disorders, namely cancer and diabetes. The incorporation of sodium salt configuration augments solubility and bioaccessibility, thus rendering it highly amenable for pharmaceutical endeavors. CAS No. 89927-09-3. Molecular formula: C5H9Na2O8P. Mole weight: 274.07.
Darapladib
Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Alternative Names: SB-480848; SB 480848; SB480848; Darapladib. Grades: >98%. CAS No. 356057-34-6. Molecular formula: C36H38F4N4O2S. Mole weight: 666.77.
Daratumumab
Daratumumab is a recombinant IgG1k monoclonal antibody that binds to CD38 and leads to cell apoptosis. Daratumumab was granted orphan drug designation for the treatment of multiple myeloma, diffuse large B cell lymphoma, follicular lymphoma, and mantle cell lymphoma. Uses: Antitumor agent. Alternative Names: Darzalex; HuMax-CD38; UNII-4Z63YK6E0E. CAS No. 945721-28-8. Molecular formula: C6466H9996N1724O2010S42. Mole weight: 145391.67.
Darunavir
Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. Uses: Hiv protease inhibitors. Alternative Names: TMC-114; TMC 114; TMC114; Prezista. Grades: ≥98%. CAS No. 206361-99-1. Molecular formula: C27H37N3O7S. Mole weight: 547.67.
Dasatinib Monohydrate
Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Uses: Antineoplastic agents. Alternative Names: BMS-354825 Monohydrate; BMS 354825 Monohydrate; BMS354825 Monohydrate; N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate. Grades: >98%. CAS No. 863127-77-9. Molecular formula: C22H28ClN7O3S. Mole weight: 506.02.
dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Alternative Names: 2'-Deoxyadenosine-5'-Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 1927-31-7. Molecular formula: C10H16N5O12P3. Mole weight: 491.18.
dATPαS
dATPαS is a modified nucleotide analog that is widely used as a substrate for various DNA polymerases. It is commonly used in DNA labeling experiments due to its incorporation into target DNA by polymerases during DNA synthesis. It has also been used to generate non-cleavable modified DNA for studying DNA repair mechanisms. Alternative Names: 2'-Deoxyadenosine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grades: ≥ 95% by HPLC. CAS No. 64145-28-4. Molecular formula: C10H16N5O11P3S (free acid). Mole weight: 507.24 (free acid).
Daunomycinone
Daunomycinone is the aglycone core structure of the anthracycline antibiotics daunorubicin and doxorubicin, lacking their sugar moiety. As a key pharmacophore, it contributes to the DNA-intercalating and topoisomerase II inhibition properties of these drugs, enabling anticancer activity. While less potent than the glycosylated forms, daunomycinone retains cytotoxic effects by generating reactive oxygen species (ROS) and disrupting DNA replication. Alternative Names: Daunorubicin Impurity A; (8S,10S)-8-Acetyl-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunorubicin EP Impurity A; (+)-Daunomycinone; NSC 109531; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; Daunomycin Aglicone; Daunomycinon; Daunorubicin Aglycone; Leukaemomycinone C; Daunorubicinone; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-; Epirubicin EP Impurity B. Grades: ≥95%. CAS No. 21794-55-8. Molecular formula: C21H18O8. Mole weight: 398.37.