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Ebselen
Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Alternative Names: SPI-1005; SPI1005; SPI 1005; Ebselen; PZ 51; PZ51; PZ-51; DR3305; DR 3305; DR-3305. Grades: >98%. CAS No. 60940-34-3. Molecular formula: C13H9NOSe. Mole weight: 274.192.
EC17, also known as Folate-FITC, is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, curculating anti-fluorescein antibodies.may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity. Alternative Names: EC17; EC 17; Folate-FITC; Folate-fluorescein conjugate. CAS No. 583037-91-6. Molecular formula: C42H36N10O10S. Mole weight: 872.87.
EC-17 Disodium salt
EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. Alternative Names: Folate-FTIC Disodium salt; FTIC-Folate Disodium salt. CAS No. 910661-33-5. Molecular formula: C42H34N10Na2O10S. Mole weight: 916.83.
Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves / protective clothing/eye protection / face protection. Uses: Sunscreening agents. Alternative Names: [(2E)-2-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl]methanesulfonic acid; 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxobicyclo(2.2.1)heptane-1-methanesulfonic acid); Ecamsule; Mexoryl SX; terephthalylidene dicamphor sulfonic acid; 92761-26-7; AC1O5SNJ; Ecamsule [USAN:USP:INN]; SCHEM. Grades: ≥ 95.0%. CAS No. 92761-26-7. Molecular formula: C28H34O8S2. Mole weight: 562.70.
eCF506
eCF506 is a potent and highl selective inhibitor towards Src tyrosine kinase with a 1000-fold selectivity over ABL. eCF506 inhibits SRC at subnanomolar concentration (IC50 < 0.5 nM). It is said that eCF506 is the first drug candidate of a second generation of Src inhibitors that will not only help to understand the complexity of some cancers but also the development of safer combination therapies. Alternative Names: eCF506; eCF-506; eCF 506.; tert-butyl N-[4-[4-amino-1-[2-[4-(dimethylamino)piperidin-1-yl]ethyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]carbamate; eCF506; Derivative 11a; GTPL9186; derivative 11a [PMID: 27115835]; tert-butyl N-[4-(4-amino-1-{2-[4-(dimethylamino)piperidin-1-yl]ethyl}-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl]carbamate. Grades:>98%. CAS No. 1914078-41-3. Molecular formula: C26H38N8O3. Mole weight: 510.643.
Eckol
Eckol. Alternative Names: Eckol;88798-74-7;4-(3,5-dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol;1-(3,5-Dihydroxyphenoxy)-2,4,7,9-tetrahydroxydibenzo-1,4-dioxin;CHEMBL471187;CHEBI:65819;4A5E8354UB;4-(3,5-dihydroxyphenoxy)oxanthrene-1,3,6,8-tetrol;4-(3,5-dihydroxyphenoxy)-dibenzo(b,e)(1,4)dioxin-1,3,6,8-tetrol;4-(3,5-Dihydroxyphenoxy)dibenzo[b,e][1,4]dioxine-1,3,6,8-tetraol;Dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-;DIBENZO(B,E)(1,4)DIOXIN-1,3,6,8-TETROL, 4-(3,5-DIHYDROXYPHENOXY)-;UNII-4A5E8354UB;SCHEMBL2562621;DTXSID40237333;BDBM50259982;AKOS040745766;DA-63108;HY-114203;CS-0079519;Q5332934;4-(3,5-DIHYDROXYPHENOXY)DIBENZO(B,E)(1,4)DIOXIN-1,3,6,8-TETROL;Dibenzo(b,e)(1,4)-dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-. Grades: 95%. CAS No. 88798-74-7. Molecular formula: C18H12O9. Mole weight: 372.28.
Econazole nitrate
Econazole nitrate (Spectazole) is an imidazole class antifungal medication.It is used as a cream under the brand names Spectazole (United States), Ecostatin (Canada), Pevaryl (Western Europe), and Pevisone (the latter consisting of the combination econazole / triamcinolone) to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. Uses: Antifungal agents. Alternative Names: 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1); 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, (±)-, mononitrate; 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, mononitrate; Imidazole, 1-[2,4-dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]-, mononitrate; (±)-Econazole nitrate; 1-[2-(4-Chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole nitrate; Ecostatin; Epi-Pevaryl; Gyno-Pevaril; Gynoryl; Ifenec; Micofugal; Micogin; NSC 243115; Palavale; Pargin; Pevaryl; R 14827; Spectazole; SQ 13050. Grades: >98%. CAS No. 24169-02-6. Molecular formula: C18H15Cl3N2O.HNO3. Mole weight: 444.70.
Ecteinascidin 770
Ecteinascidin 770 is an alkaloid with potent anti-cancer activities, which inhibits U373MG cells with an IC50 of 4.83 nM. Alternative Names: Ecteinascidine 770; Et-770. Grades: ≥99%. CAS No. 114899-80-8. Molecular formula: C40H42N4O10S. Mole weight: 770.85.
EDA-ATP - Cy5
EDA-ATP - Cy5 is a luminous tool, serving as a vital fluorochrome unveiling the realms of compound. Renowned for its contribution to bioimaging and facilitation of ATP recognition within cells, EDA-ATP illuminates the cellular dynamics. Alternative Names: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Adenosine-5'-triphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C46H60N9O21P3S2(free acid). Mole weight: 1232.07 (free acid).
EDA-ATPγS - Cy5
EDA-ATPγS-Cy5 is a fluorescent kinase assay substrate used for analyzing kinase activities in vitro. It serves as a useful tool for researchers studying signaling pathways and drug discovery efforts surrounding diseases such as cancer and autoimmune disorders. Alternative Names: 2'/3'-O-(2-Aminoethyl-carbamoyl)-adenosine-5'-(γ-thio)-triphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 90 % by HPLC, contains approx. 5 % EDA-ADP-dye. Molecular formula: C46H60N9O20P3S3(free acid). Mole weight: 1248.13 (free acid).
EDA-m7GTP
EDA-m7GTP is a widely employed chemical compound assuming a pivotal role as a substrate during a myriad of enzymatic reactions that oversee RNA modification and processing. Alternative Names: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3(free acid). Mole weight: 623.30 (free acid).
Edaravone Impurity V
An impurity of Edaravone, a medication for the recovery from stroke. Alternative Names: 4,4-Bis(1-phenyl-3-methyl-5-oxo-3-pyrazoline-4-yl)-1-phenyl-3-methyl-1H-pyrazole-5(4H)-one. Grades: >95%. CAS No. 124009-63-8. Molecular formula: C30H26N6O3. Mole weight: 518.577.
Edaravone Trimer
Edaravone Trimer is an impurity of Edaravone. Edaravone is a novel potent free radical scavenger that reduces reactive oxygen species, inhibits apoptosis, and blocks nonenzymatic peroxidation and lipoxygenase activity. Alternative Names: 5,5',5''-trimethyl-2,2',2''-triphenyl-[4,4':4',4''-Ter-4H-pyrazole]-3,3',3''(2H,2'H,2''H)-trione; 4,4-bis(3-methyl-5-oxo-1-phenyl(2-pyrazolin-4-yl))-3-methyl-1-phenyl-2-pyrazol in-5-one; 2-Phenyl-5-methyl-4,4-bis(2-phenyl-3-oxo-5-methyl-3,4-dihydro-2H-pyrazole-4-yl)-3,4-dihydro-2H-pyrazole-3-one. Grades: 98%. CAS No. 68195-63-1. Molecular formula: C30H26N6O3. Mole weight: 518.58.
EDDHA
EDDHA, a compound utilized in the biomedical field, serves as an effective iron chelator for managing conditions such as iron deficiency anemia and iron overload disorders. Its intricate molecular structure allows for targeted and precise binding of iron ions, highlighting its therapeutic potential in clinical settings. Alternative Names: EDDHA; Ethylenediamine-N,N'-di(o-hydroxyphenylacetic acid). Grades: 98%. CAS No. 1170-02-1. Molecular formula: C18H20N2O6. Mole weight: 360.36.
Edelfosine
Edelfosine, an orally administered antileishmanial drug, has anti-metastasis effect in experimental tumors. Edelfosine is a synthetic lysophospholipid analogue that acts as an inhibitor of phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells) and an agonist at platelet-activating factor (PAF) receptors. Uses: Phosphodiesterase inhibitors. Alternative Names: ALP; 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide; 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine; ET-18-OMe; ET 18-OCH3; rac-1-Octadecyl-2-methoxyglycero-3-phosphocholine; NSC-324368; (±)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium hydroxide inner salt 4-oxide. Grades: ≥95%. CAS No. 70641-51-9. Molecular formula: C27H58NO6P. Mole weight: 523.73.
Edoxaban
Edoxaban is an oral factor Xa (FXa) inhibitor, also contraindicated in patients with active pathological bleeding. Uses: A direct factor xa inhibitor. Alternative Names: DU-176; DU 176; DU176DU-176b;N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide. Grades: ≥98%. CAS No. 480449-70-5. Molecular formula: C24H30CLN7O4S. Mole weight: 548.06.
Edoxaban impurity G
An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Alternative Names: Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-; N1-(5-Chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide; 4-epi-Edoxaban. Grades: >95%. CAS No. 1255529-26-0. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06.
Edoxaban impurity G tosylate
An impurity of Edoxaban, an oral anticoagulant drug and a direct factor Xa inhibitor. Alternative Names: N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate; Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, compd. with 4-methylbenzenesulfonate (1:1); N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide tosylate. CAS No. 2852734-47-3. Molecular formula: C31H38ClN7O7S2. Mole weight: 720.26.
Edoxaban impurity H
Edoxaban Impurity. Alternative Names: N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide. Grades: > 95%. CAS No. 1255529-28-2. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06.
Edoxaban N-Oxide
An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Alternative Names: (5S)-5-Oxide Edoxaban; 2-(((1R,2S,5S)-2-(2-((5-Chloropyridin-2-yl)amino)-2-oxoacetamido)-5-(dimethylcarbamoyl)cyclohexyl)carbamoyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 5-Oxide. Grades: ≥95%. CAS No. 2244103-96-4. Molecular formula: C24H30ClN7O5S. Mole weight: 564.06.
Edoxaban Oxoacetic Acid Impurity
An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Alternative Names: Edoxaban metabolite M1; Edoxaban M1 Impurity; 4S-Des-3-chloropyridine Edoxaban. Grades: 95%. CAS No. 767625-11-6. Molecular formula: C19H27N5O5S. Mole weight: 437.52.
Edoxaban (RSS)-Isomer
An impurity of Edoxaban, which is an oral anticoagulant drug and a direct factor Xa inhibitor. Alternative Names: Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-; N1-(5-Chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide; N-(5-Chloropyridin-2-yl)-N'-[(1R,2S,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide. CAS No. 1255529-25-9. Molecular formula: C24H30ClN7O4S. Mole weight: 548.06.
Edoxaban Tosylate Hydrate
In human plasma, Edoxaban doubles prothrombin time and activates partial thromboplastin time at 0.256 and 0.508 μM, respectively. Alternative Names: N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-Toluenesulfonate hydrate; N-(5-Chloropyridin-2-yl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide mono(p-toluenesulfonate) hydrate; Edoxaban p-toluenesulfonate monohydrate. Grades: >98%. CAS No. 1229194-11-9. Molecular formula: C24H30ClN7O4S.C7H8O3S.H2O. Mole weight: 738.27.
Edoxaban TsOH salt
Edoxaban is an oral factor Xa (FXa) inhibitor, also contraindicated in patients with active pathological bleeding. Uses: A direct factor xa inhibitor. Alternative Names: Edoxaban Tosylate; N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;4-methylbenzenesulfonic acid. Grades: ≥98%. CAS No. 480449-71-6. Molecular formula: C31H38ClN7O7S2. Mole weight: 720.26.
EDTA-2K Dihydrate
Used to eliminate the inhibition effect of trace heavy metals on enzyme-catalyzed reactions. Alternative Names: Ethylenediaminetetraacetic acid dipotassium salt dihydrate; EDTA dipotassium salt dihydrate; Potassium 2,2'-((2-(bis(carboxymethyl)amino)ethyl)azanediyl)diacetate dihydrate; Dipotassium ethylenediaminetetraacetate dihydrate; Ethylenediamine-N,N,N',N'-tetraacetic acid dipotassium salt dihydrate. Grades: ≥98%. CAS No. 25102-12-9. Molecular formula: C10H14K2N2O8.2H2O. Mole weight: 404.45.
EDTA-3K Dihydrate
Used to eliminate the inhibition effect of trace heavy metals on enzyme-catalyzed reactions. Alternative Names: EDTA tripotassium salt Dihydrate (EDTA-3K·2H2O); Tripotassium ethylenediaminetetraacetate Dihydrate; N,N'-1,2-Ethanediylbis[N-(carboxymethyl)glycine Tripotassium Salt Dihydrate; Ethylenediaminetetraacetic Acid Tripotassium Salt Dihydrate. Grades: ≥98%. CAS No. 65501-24-8. Molecular formula: C10H13K3N2O8.2H2O. Mole weight: 442.54.
EDTA disodium salt dihydrate
Ethylenediaminetetraacetic acid (EDTA) acts as a hexadentate chelating agent that binds to iron and calcium ions. Alternative Names: Disodium ethylenediaminetetraacetate dihydrate; Acetic acid, (ethylenedinitrilo)tetra-, disodium salt, dihydrate; Disodium EDTA dihydrate; Ethylenediaminetetraacetic acid sodium salt dihydrate; Ethylenediamine-N,N,N',N'-tetraacetic Acid Disodium Dihydrate. Grades: ≥97%. CAS No. 6381-92-6. Molecular formula: C10H14N2Na2O8.2(H2O). Mole weight: 372.23.
edta iron(iII) sodium salt
Sodium Iron EDTA is often used in children nutrition as a source of iron. Alternative Names: ((ethylenedinitrilo)tetraacetato)-ferrate(1-sodium; [[N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',O,N,O,N']-,sodium,(OC-6Ferrate(1-); aceticacid,(ethylenedinitrilo)tetra-,sodiumsalt,ironcomplex; calmosine; edathamilmonosodiumferricsalt. Grades: >90.0%(T). CAS No. 15708-41-5. Molecular formula: C10H12FeN2NaO8. Mole weight: 367.05.
EDTA-Zn-Amm
EDTA-Zn-Amm. Alternative Names: EDTA-Zn-Amm; Ethylenediaminetetraacetate-zinc-ammonia complex. Grades: 95%. CAS No. 67859-51-2. Molecular formula: C10H20N4O8Zn. Mole weight: 389.70.
e,e-2,6-NONADIEN-1-AL
e,e-2,6-Nonadien-1-al, a compound prevalent in biomedical research, showcases promise in pharmaceutical innovation. Its versatile nature positions it as a compelling candidate for drug development across a spectrum of diseases. Alternative Names: Fatty odor with fresh green, herbaceous, cucumber, and melon notes. Grades: colorless to slightly yellow liquid. CAS No. 17587-33-6. Molecular formula: C9H14O. Mole weight: 138.21.
Efaroxan hydrochloride
Efaroxan hydrochloride is a potent and selective α2 adrenoceptor antagonist and imidazoline I1 receptor ligand (pKi = 7.87, 7.42, 5.74, 7.28 and < 5 for α 2A, α2B, α2C, I1, and I2 receptors, respectively). Efaroxan promotes insulin secretion, at a site distinct from I1 or I2 (the putative I3 receptor) in vitro and in vivo. Alternative Names: Efaroxan HCl; RX 821037A; RX821037A; RX-821037A; EU-0100521; EU0100521; EU 0100521; 2-(2-Ethyl-2,3-dihydro-2-benzofuranyl)-4,5-dihydro-1H-imidazole hydrochloride. Grades: ≥99% by HPLC. CAS No. 89197-00-2. Molecular formula: C13H16N2O.HCl. Mole weight: 252.74.
EFdA-TP
EFdA-TP is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP inhibits HIV-1 RT with multiple mechanisms. Alternative Names: 2'-Deoxy-4'-Ethynyl-2-Fluoroadenosine 5'-(Tetrahydrogen Triphosphate); Islatravir triphosphate. Grades: ≥98%. CAS No. 950913-56-1. Molecular formula: C12H15FN5O12P3. Mole weight: 533.19.
Effulgence-NPHA
Effulgence-NPHA. Alternative Names: CUPFERRON; COPPERONE; AMMONIUM SALT OF NITROSOPHENYLHYDROXYLAMINE; AMMONIUM-N-NITROSOPHENYL-HYDROXYLAMINE; AMMONIUM NITROSOPHENYLHYDROXYLAMINE; NITROSOPHENYLHYDROXYLAMINE AMMONIUM SALT; NITROPHENYLHYDROXYLAMINE AMMONIUM; N-HYDROXY-N-NITROSOBENZENAMINE AMMONIUM. Grades: Purity >98%. CAS No. 135-20-6. Molecular formula: C6H9N3O2. Mole weight: 155.15.
Efinaconazole 2R,3R Epoxy triazole
An enantiomer of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Alternative Names: 1-[[(2R,3R)-2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole; (2R-trans)-1-[[2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole. Grades: > 95%. CAS No. 135270-13-2. Molecular formula: C12H11F2N3O. Mole weight: 251.23.
Efinaconazole (2R,3S) Distereomer
An impurity of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Grades: 90%. CAS No. 2055038-60-1. Molecular formula: C18H22F2N4O. Mole weight: 348.4.
Efinaconazole (2S,3R) Distereomer
An impurity of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Grades: 90%. CAS No. 2055038-61-2. Molecular formula: C18H22F2N4O. Mole weight: 348.4.
Efinaconazole 2S,3S Epoxy triazole
An enantiomer of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Alternative Names: 1-[[(2S,3S)-2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole; (2S-trans)-1-[[2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole. Grades: > 95%. CAS No. 135270-10-9. Molecular formula: C12H11F2N3O. Mole weight: 251.23.
Efinaconazole Related Impurity 3
The S,S-enantiomer of Efinaconazole, a medication used to treat toenail infection caused by fungus. Alternative Names: ent-Efinaconazole; (2S,3S)-Efinaconazole; (αS,βS)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidine ethanol; [S-(R*,R*)]-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidine ethanol. Grades: > 95%. CAS No. 164650-45-7. Molecular formula: C18H22F2N4O. Mole weight: 348.39.
Efinaconazole Related Impurity 4
An enantiomer of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Alternative Names: Efinaconazole 2S,3R Epoxy triazole; 1-(((2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole; 1-{[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl]methyl}-1H-1,2,4-triazole; (2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane. Grades: > 95%. CAS No. 135270-07-4. Molecular formula: C12H11F2N3O. Mole weight: 251.24.
Eflornithine hydrochloride
Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. Alternative Names: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; MDL 71782 hydrochloride; RMI 71782 hydrochloride; MDL-71782 hydrochloride; RMI-71782 hydrochloride; α-difluoromethylornithine hydrochloride; Vaniqa hydrochloride. Grades: >98%. CAS No. 68278-23-9. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63.
Efonidipine hydrochloride monoethanolate
The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders. Uses: The hydrochloride monoethanolate salt form of efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders. Alternative Names: Efonidipine hydrochloride ethanol; Efonidipine hydrochloride ethanolate; NZ 105 ethanolate; NZ105 ethanolate; NZ-105 ethanolate; EFONIDIPINE HYDROCHLORIDE MONOETHANOLATE; 111011-76-8; Efonidipine.HCl ethanolate. Grades: >98%. CAS No. 111011-76-8. Molecular formula: C36H45ClN3O8P. Mole weight: 631.66.
eFT-508
eFT-508 is a selective inhibitor of MNK1/2 (IC50s = 2.4 nM and 1 nM respectively) inhibiting MNK1/2-mediated signaling and the phosphorylation of certain regulatory proteins. It acts against tumor. Alternative Names: SCHEMBL17362622; AKOS030627405; ZINC575623807; CS-5841; CS 5841; CS5841; 6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione; eFT508. Grades: 98%. CAS No. 1849590-01-7. Molecular formula: C17H20N6O2. Mole weight: 340.38.
EGDS
EGDS. Alternative Names: EGDS; Ethylene glycol distearate. Grades: 190.0~210.0(KOHmg/g). CAS No. 627-83-8. Molecular formula: C38H74O4. Mole weight: 594.99.
Egg Liss Rhod PE
Egg Liss Rhod PE is a fluorescent labelling lipid. Alternative Names: L-α-Phosphatidylethanolamine-N-(lissamine rhodamine B sulfonyl) (Ammonium Salt) (Egg-Transphosphatidylated, Chicken). Grades: >99%. CAS No. 383906-59-0. Molecular formula: C66H107N4O14PS2. Mole weight: 1275.67.
Egg PG
BOC Sciences provides high-quality Egg PG for your projects. Alternative Names: PGs (egg); L-α-phosphatidylglycerol (Egg, Chicken) (sodium salt). Grades: ≥98%. CAS No. 383907-64-0. Molecular formula: C40H76NaO10P. Mole weight: 771.
Egg SM
Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes. Sphingomyelin obtained from natural sources, such as eggs or bovine brain, contains fatty acids of various chain length. Alternative Names: Sphingomyelin (Egg, Chicken); 16:0 SM; Hexadecanoyl Sphingomyelin; N-hexadecanoyl-D-erythro-sphingosylphosphorylcholine. Grades: 98%. CAS No. 383907-87-7. Molecular formula: C39H79N2O6P. Mole weight: 703.03.
Egg Trans PE
Phosphatidylethanolamine (PE) is a phospholipid in all living organism. The egg yolk contains high levels of unsaturated PE which accounts to 83.10%. Alternative Names: L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken). Grades: >99%. CAS No. 383907-63-9. Molecular formula: C39H76NO8P. Mole weight: 717.99.
Egg Yolk Lecithin
Egg Phosphatide Extract can be used to prevent and treat atherosclerosis. Alternative Names: Lipoid E 100; Lipoid E 75; Lipoid E 80; Lipoid E80S; Lipoid EPC; Nikkol Lecinol Y 10; Nikkol Lecinol Y 10E; Ovothin 120; Ovotin 160; PL 100; PL 100E; PL 100H; PL 100LE; PL 100M; PL 30S; PL 60; Phosphatides, egg yolk; Phospholipon E 80; QPFCPL 100P; Yokuretopauda LP; Yolk lecithin; Yolkin IP Lecithin; Phospholipids egg. CAS No. 93685-90-6.
Egg yolk oil
Egg yolk oil. CAS No. 8001-17-0.
EGT1442
EGT1442 is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. It significantly prolonged the median survival of SHRSP rats. It attenuates blood glucose and HbA(1c) levels and prolongs the survival of stroke-prone rats in db/db mice. It showed favorable properties both in vitro and in vivo and could be beneficial to the management of type 2 diabetic patients. It was developed by Theracos and in clinic phase 1 trials. Uses: Egt1442 showed favorable properties and could be beneficial to the management of type 2 diabetic patients. Alternative Names: THR1442; THR-1442; THR 1442; EGT1442; EGT-1442; EGT 1442; Bexagliflozin; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol;Bexagliflozin;THR1442;EGT0001442;EGT-1442;THR-1442;EGT-0001442;(2S,4R,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grades: >98%. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 464.94.
EGTA acetoxymethyl ester
EGTA acetoxymethyl ester is a cell-permeant form of EGTA, a calcium chelator. This indicator has been used for detecting intracellular calcium. Alternative Names: EGTA/AM; EGTA AM; EGTA tetra(acetoxymethyl ester). Grades: 95%. CAS No. 99590-86-0. Molecular formula: C26H40N2O18. Mole weight: 668.6.
Eicosane
Eicosane is a long-chain saturated aliphatic hydrocarbon that is an inefficient fuel in the petrochemical industry. It is a natural product found in Erucaria microcarpa, Microcystis aeruginosa and Sargassum fusiforme. Alternative Names: MPCM 37; n-Eicosane; NSC 62789; Parafol 20Z. Grades: ≥95%. CAS No. 112-95-8. Molecular formula: C20H42. Mole weight: 282.55.
4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2. Alternative Names: 4'-fluorouridine;1613589-24-4;4'-C-Fluoro-uridine;1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;1613591-91-5;SCHEMBL6839661;RDCYLPRXPILMRP-JVZYCSMKSA-N;AMY30709;EX-A6732;DA-70078;MS-23688;4'-fluorouridine (4'-FlU, EIDD-2749)?;1-((2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: 98%. CAS No. 1613589-24-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
eIF4A3-IN-5
eIF4A3-IN-5, a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII, has the potential to study eIF4A dependent diseases, including cancer. (Extracted from patent US20170145026A1). Alternative Names: 6H-Cyclopenta[4,5]furo[3,2-c]pyridine-7-carboxylic acid, 5a-(4-cyanophenyl)-5a,7,8,8a-tetrahydro-8,8a-dihydroxy-1,3-dimethoxy-6-phenyl-, (5aR,6S,7R,8R,8aS)-. CAS No. 2100145-31-9. Molecular formula: C26H22N2O7. Mole weight: 474.46.
eIF4E-IN-1
eIF4E-IN-1, a potent eIF4E inhibitor, inhibits immunosuppression components such as the immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immunosuppression in certain diseases, such as cancer and infectious diseases. (Extracted from patent WO2021003194A1, compound Y). Alternative Names: Thieno[3,2-b]pyridine-3-carboxylic acid, 7-[5-chloro-2-[2-[5-cyano-2-methyl-6-(4-methyl-1-piperazinyl)-4-oxo-7-(trifluoromethyl)-3(4H)-quinazolinyl]ethoxy]phenyl]-5-methyl-. CAS No. 2573979-31-2. Molecular formula: C33H28ClF3N6O4S. Mole weight: 697.13.
Elacestrant dihydrochloride
Elacestrant dihydrochloride is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. It is also a selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Alternative Names: RAD1901 dihydrochloride; (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6R)-, hydrochloride (1:2). Grades: 98%. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56.
Elacestrant S enantiomer
Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Alternative Names: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63.
Elacestrant S enantiomer dihydrochloride
Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Alternative Names: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56.
Elacridar
Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Alternative Names: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654.
Elacridar hydrochloride
Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Alternative Names: Elacridar HCl; N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide hydrochloride. CAS No. 143851-98-3. Molecular formula: C34H33N3O5.HCl. Mole weight: 600.10.
Elacytarabine
Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Alternative Names: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67.
Elafibranor
Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Alternative Names: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E)-1-[4-(Methylthio)phenyl]-3-[3,5-dimethyl-4-[(carboxydimethylmethyl)oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49.
Elagolix
Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Alternative Names: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6.
Elagolix sodium
Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Alternative Names: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate; NBI56418; NBI-56418; NBI 56418. Grades: 98%. CAS No. 832720-36-2. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.58.