BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| ELASTIN | ELASTIN. Alternative Names: Elastins; ELASTIN, BOVINE; ELASTIN, BOVINE NECK LIGAMENT; ELASTIN, BOVINE NECK LIGAMENT, ALKALINE EXTRACTED; ELASTIN; ELASTIN, WATER SOLUBLE; Elastin from bovine neck ligament; ELASTIN, SOLUBLE, FROM HUMAN LUNG. CAS No. 9007-58-3. Molecular formula: C27H48N6O6. |  |
| Elastins,hydrolyzates | Elastins,hydrolyzates. Grades: 95%. CAS No. 91080-18-1. | |
| Eldecalcitol | Eldecalcitol, a vitamin D analog, has strong effects to reduce calcium reabsorption into the body from bones, therefore increasing bone mineral density, and to increase calcium absorption in intestines. Alternative Names: Edirol; ED-71; 2-(3-Hydroxypropoxy)-1,25-dihydroxyvitamin D3; 2-(3-Hydroxypropoxy)calcitriol; 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3. Grades: >98%. CAS No. 104121-92-8. Molecular formula: C30H50O5. Mole weight: 490.72. | |
| Eldecalcitol Intermediate A | Eldecalcitol Intermediate A is an intermediate of eldecalcitol, a vitamin D3 analogue for the treatment of osteoporosis. Eldecalcitol is more active in bone resorption inhibition in comparison with alfacalcidol. Alternative Names: 3-[(1R,2R,4Z,6R)-2,6-bis[[tert-butyl(dimethyl)silyl]oxy]-4-(2-diphenylphosphorylethylidene)-3-methylidenecyclohexyl]oxypropoxy-tert-butyl-dimethylsilane. CAS No. 200636-54-0. Molecular formula: C42H71O5PSi3. Mole weight: 771.25. | |
| Elderberry Extract | The main active ingredients of Elderberry Extract are Anthocyandins and Anthocyanin, which have antiviral, antioxidant, natural pigment, anti-inflammatory effects. It can be usesd as cosmetics material. Grades: 5%-50%; 10:1. CAS No. 84603-58-7. | |
| Eleclazine | Eleclazine is a selective Sodium channel antagonist. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart's electrical cycle) in patients with long QT-3 (LQT3) syndrome. Phase III clinical trilas for the treatment of Long QT syndrome, Phase II/III clinical trilas for the treatment of Hypertrophic cardiomyopathy and Phase II clinical trilas for the treatment of Ventricular arrhythmias are on-going. Uses: Long qt syndrome;hypertrophic cardiomyopathy;ventricular arrhythmias. Alternative Names: GS-6615; GS 6615; GS6615; Eleclazine. 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]- 3,4-dihydro-1,4-benzoxazepin-5(2H)-one. Grades: 95%. CAS No. 1443211-72-0. Molecular formula: C21H16F3N3O3. Mole weight: 415.37. | |
| ELENAIC ACID | ELENAIC ACID is a potential treatment for cancer due to its apoptotic and anti-proliferative effects on cancer cells. It has shown promise in inhibiting tumor growth and inducing cell death in various cancer types. Alternative Names: ELENAIC ACID; elenolic acid. Grades: 98%. CAS No. 34422-12-3. Molecular formula: C11H14O6. Mole weight: 242.23. | |
| Eleutheroside B1 | Eleutheroside B1 is a coumarin with anti-human influenza virus efficacy. Alternative Names: Isofraxidin-7-O-a-D-glucoside. Grades: 98%. CAS No. 16845-16-2. Molecular formula: C17H20O10. Mole weight: 384.33. | |
| Eleutheroside E | Eleutheroside E has anti-inflammatory effect by inhibiting NF-κB activities. Uses: Anti-inflammatory. Alternative Names: Acanthoside D; Eleutheroside E. Grades: >98%. CAS No. 39432-56-9. Molecular formula: C34H46O18. Mole weight: 742.72. | |
| Elexacaftor | Elexacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector used as a medication for cystic fibrosis treatment in combination with ivacaftor and tezacaftor. Alternative Names: VX-445; VX445; (S)-N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide. Grades: 98%. CAS No. 2216712-66-0. Molecular formula: C26H34F3N7O4S. Mole weight: 597.65. | |
| Eliglustat hemitartrate | Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1). It was developed by Genzyme Corp and has been listed by the FDA August 2014. Alternative Names: Genz-112638; Genz 112638; Genz112638; Eliglustat tartrate; Bis(N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1- ylmethyl)ethyl)octanamide) (2R,3R)-2,3-dihydroxybutanedioate; Octanamide, N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1- pyrrolidinylmethyl)ethyl)-, (2R,3R)-2,3-dihydroxybutanedioate; N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide (2R,3R)-2,3-dihydroxybutanedioic acid. Grades: >98%. CAS No. 928659-70-5. Molecular formula: C50H78N4O14. Mole weight: 959.17. | |
| Elsulfavirine | Elsulfavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment and prevention of human immunodeficiency virus (HIV) infection. Uses: Anti-hiv agents. Alternative Names: Elpida; Benzeneacetamide, 4-bromo-3-(3-chloro-5-cyanophenoxy)-N-[2-chloro-4-[[(1-oxopropyl)amino]sulfonyl]phenyl]-2-fluoro-; 4-Bromo-3-(3-chloro-5-cyanophenoxy)-N-[2-chloro-4-[[(1-oxopropyl)amino]sulfonyl]phenyl]-2-fluorobenzeneacetamide. Grades: ≥95%. CAS No. 868046-19-9. Molecular formula: C24H17BrCl2FN3O5S. Mole weight: 629.28. | |
| Elvitegravir | Elvitegravir is an HIV-1 integrase strand transfer inhibitor (INSTI) for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Anti-retroviral agents. Alternative Names: GS-9137; GS 9137; GS9137; JTK-303; JTK 303; JTK303; EVG; D06677; D 06677; D-06677. Grades: ≥98%. CAS No. 697761-98-1. Molecular formula: C23H23ClFNO5. Mole weight: 447.88. | |
| Elvucitabine | Elvucitabine. Uses: A novel antiviral agent. Alternative Names: Elvucitabine;181785-84-2;beta-L-Fd4C;L-Fd4C.beta.-L-Fd4C;ACH-126,443;L-F-D4C;ACH-126443;4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2-one;L-D4FC;M09BUF90C0;4-amino-5-fluoro-1-((2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidin-2(1H)-one;4-amino-5-fluoro-1-[(2s,5r)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2(1h)-one;2(1H)-Pyrimidinone, 4-amino-1-((2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl)-5-fluoro-;2(1H)-Pyrimidinone, 4-amino-1-[(2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-;Elvucitabine [USAN];Elvucitabine [USAN:INN];UNII-M09BUF90C0;ACH 126443; Beta-L-Fd4C;ACH 126443;ACH 126,443;B-L-Fd4C;Elvucitabine (USAN/INN);ELVUCITABINE [INN];CHEMBL38700;(-)Fd4C;SCHEMBL1649928;beta-L-2',3'-Dideoxy-2',3'-didehydro-5-fluorocytidine;DTXSID20171185;BDBM50421604;AKOS030528240;DB06236;DB-229042;HY-117582;CS-0066557;NS00068127;D03981;J-011630;Q1334337.beta.-L-2',3'-Didehydro-2',3'-dideoxy-5-fluorocytidine;2(1H)-Pyrimidinone, 4-amino-1-(2,5-dihydro-5-(hydroxymethyl)-2-furanyl)-5-fluoro-, (2S-cis)-. Grades: 95%. CAS No. 181785-84-2. Molecular formula: C9H10FN3O3. Mole weight: 227.19. | |
| Emamectin Benzoate | Emamectin Benzoate is the Emamectin derivative. Emamectin, also called as Proclaim, is widely used as an insecticide because of its chloride channel activation properties. Uses: Antiparasitic agents. Alternative Names: Proclaim; Proclaim 5SG; Denim; Methylamino abamectin benzoate; Shot Wan; Denim (pesticide); Sch 58854; MK 244. Grades: 95.0% (sum of isomers, including Benzoate). CAS No. 155569-91-8. Molecular formula: C56H81NO15. Mole weight: 1008.24. | |
| EMD638683 | EMD638683 is a potent SGK1 inhibitor with an IC50 of 3 μM. Alternative Names: EMD638683; EMD 638683; EMD-638683. Grades: >98%. CAS No. 1181770-72-8. Molecular formula: C18H18F2N2O4. Mole weight: 364.34. | |
| EMERALDINE BASE POLYANILINE | EMERALDINE BASE POLYANILINE. Alternative Names: EMERALDINE BASE POLYANILINE; POLYANILINE, EMERALDINE BASE; POLYANILINE, EMERALDINE FORM; POLYANILINE (EMERALDINE SALT). CAS No. 5612-44-2. | |
| Emeramide | Emeramide is a mercury chelator and an antioxidant, for the treatment of mercury poisoning. The molecule consists of two thiol groups and linked via a pair of amide groups. Alternative Names: BDTH2; N,N'-bis(2-mercaptoethyl)isophthalamide; 1-N,3-N-bis(2-sulfanylethyl)benzene-1,3-dicarboxamide. Grades: >98%. CAS No. 351994-94-0. Molecular formula: C12H16N2O2S2. Mole weight: 284.39. | |
| Emerest 2452 | Emerest 2452. CAS No. 66082-42-6. Molecular formula: C45H88O9. Mole weight: 773.20. | |
| Emicizumab | Emicizumab is a bispecific monoclonal antibody that binds to both the activated coagulation factor IX and to factor X. Emicizumab has been used in the management and treatment of hemophilia A. Alternative Names: Hemlibra. CAS No. 1610943-06-0. | |
| Emixustat | Emixustat, a novel visual cycle modulator, is a nonretinoid compound that directly inhibits RPE65, but does not bind to RAR/RXR retinoid receptors or antagonize retinoid binding proteins. Alternative Names: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol; ACU-4429; emixustat. CAS No. 1141777-14-1. Molecular formula: C16H25NO2. Mole weight: 263.38. | |
| Emixustat hydrochloride | The hydrochloride salt form of Emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration. Uses: The hydrochloride salt form of emixustat which could effectively inhibit the production of 11-cis-retinol which is related to age-related macular degeneration. Alternative Names: Emixustat (hydrochloride); UNII-AP4OF2M98B; AP4OF2M98B; EMIXUSTAT HYDROCHLORIDE; 1141934-97-5; Emixustat hydrochloride (USAN). Grades: 98%. CAS No. 1141934-97-5. Molecular formula: C16H26ClNO2. Mole weight: 299.84. | |
| Empagliflozin Destetrahydrofuran Impurity | An impurity of empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: O-Desethyl Dapagliflozin; (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grades: 98%. CAS No. 864070-37-1. Molecular formula: C19H21ClNO6. Mole weight: 380.83. | |
| Empagliflozin Impurity C | Empagliflozin impurity. Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3R)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol; 3'-Epi-Empagliflozin; Empagliflozin (R)-Isomer. Grades: > 95%. CAS No. 864070-43-9. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empagliflozin Methyl Acetate | Empagliflozin Methyl Acetate is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: ((2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl Acetate. CAS No. 2452301-09-4. Molecular formula: C25H29ClO8. Mole weight: 492.95. | |
| Empagliflozin Ortho Isomer | Empagliflozin Ortho Isomer is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Alternative Names: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grades: ≥98%. CAS No. 2452301-30-1. Molecular formula: C23H27ClO7. Mole weight: 450.91. | |
| Empenthrin | Empenthrin. Alternative Names: Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 1-ethynyl-2-methyl-2-penten-1-yl ester; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 1-ethynyl-2-methyl-2-pentenyl ester; Bunganon VA Plate; d-Empenthrin; MA 108; S 2852; S 2852 Forte; S 2852F; Vaporthrin. Grades: 95%. CAS No. 54406-48-3. Molecular formula: C18H26O2. Mole weight: 274.40. | |
| Emraclidine | Emraclidine is a muscarinic M4 receptor positive allosteric modulator. Alternative Names: 1-(2,4-dimethyl-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-2-{1-[2-(trifluoromethyl)pyridin-4-yl]azetidin-3-yl}ethan-1-one. CAS No. 2170722-84-4. Molecular formula: C20H21F3N4O. Mole weight: 390.41. | |
| Emricasan | Emricasan is a pan-caspase inhibitor with antiapoptotic and antiinflammatory activity. It was shown that emricasan decreased caspase activity, serum alanine aminotransferase (ALT), and hepatic fibrogenesis in a murine model of non-alcoholic steatohepatitis. Emricasan has been granted fast track designation by the FDA for the treatment of non-alcoholic steatohepatitis cirrhosis. Uses: Liver disease therapy. Alternative Names: IDN-6556; IDN6556; IDN 6556; PF 03491390; PF-03491390; PF03491390; (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid. Grades: 99.59%. CAS No. 254750-02-2. Molecular formula: C26H27F4N3O7. Mole weight: 569.51. | |
| Emtricitabine triphosphate | (-)-Emtricitabine triphosphate, an antiviral drug, is commonly prescribed for HIV-1 infection. It suppresses virus replication by inhibiting the reverse transcriptase enzyme. Consequently, the viral load decreases, and immune efficacy increases, delaying the onset of AIDS. Alternative Names: EMTRICITABINE TRIPHOSPHATE;CHEMBL341421;145819-92-7;EMTRICITABINE 5'-TRIPHOSPHATE;[[(2r,5s)-5-(4-Azanyl-5-Fluoranyl-2-Oxidanylidene-Pyrimidin-1-Yl)-1,3-Oxathiolan-2-Yl]methoxy-Oxidanyl-Phosphoryl] Phosphono Hydrogen Phosphate;((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl tetrahydrogen triphosphate;[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl tetrahydrogen triphosphate;1RY;L-FSddCTP;Emtricitabine Triphosphate Sodium Salt;Discontinued See E525075;(-)-FTCTP;(-)-FTC-TP;BDBM50138405;HY-131596;CS-0137524;Q27452391;(-)-2',3'-Deoxy-5-fluoro-3'-thiacytidine-5'-triphosphate;EMTRICITABINE METABOLITE (EMTRICITABINE 5'-TRIPHOSPHATE);((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyltetrahydrogentriphosphate;[[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate;TRIPHOSPHORIC ACID, P-(((2R,5S)-5-(4-AMINO-5-FLUORO-2-OXO-1(2H)-PYRIMIDINYL)-1,3-OXATHIOLAN-2-YL)METHYL) ESTER. CAS No. 145819-92-7. Molecular formula: C8H13FN3O12P3S. Mole weight: 487.19. | |
| Emtricitabine triphosphate tetrasodium salt | (-)-Emtricitabine triphosphate sodium salt is robustly categorized as an efficacious nucleoside reverse transcriptase inhibitor, illuminating its legalizing role in the therapeutic research against HIV infection. It can seize upon the function of HIV reverse transcriptase to lay siege to the viral replication behavior, thus endeavoring to strike back effectively against this malady. Uses: A metabolite of (-)-emtricitabine (e525000). Alternative Names: 1188407-46-6;(-)-EMTRICITABINE TRIPHOSPHATE TETRASODIUM SALT;Sodium ((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl triphosphate;tetrasodium;[[[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate;Sodium((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyltriphosphate. Grades: ≥ 95% (HPLC). CAS No. 1188407-46-6. Molecular formula: C8H9FN3Na4O12P3S. Mole weight: 575.11. | |
| Enavogliflozin | Enavogliflozin is an antidiabetic agent, and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor. Alternative Names: DWP-16001. CAS No. 1415472-28-4. Molecular formula: C24H27ClO6. Mole weight: 446.92. | |
| Enbucrilate | Enbucrilate is a surgical tissue adhesive. Enbucrilate is under clinical trials for its intervention in gastric variceal bleeding. Alternative Names: Butyl 2-cyanoacrylate; Histoacryl; N-butyl cyanoacrylate; N-Butylcyanoacrylate; butyl 2-cyanoprop-2-enoate. Grades: >98%. CAS No. 6606-65-1. Molecular formula: C8H11NO2. Mole weight: 153.181. | |
| Encaleret | Encaleret is a calcium-sensing receptor (CaSR) antagonist. But in Oct 2011, Phase-II for Osteoporosis in USA was discontinued. Uses: Osteoporosis. Alternative Names: 1214922-52-7 (sulfate salt);JIT-305; JIT 305; JIT305; 2'-((R)-1-((R)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl-[1,1'-biphenyl]-4-carboxylic acid. Grades: 98%. CAS No. 787583-71-5. Molecular formula: C29H33ClFNO4. Mole weight: 514.03. | |
| ENCALERET SULFATE | This active molecular is an CaSR (calcium-sensing receptor antagonist) under the developmet of Tobacco and Merck & Co. Calcium-sensing receptor is a member of the G protein-coupled receptor and it is very important to modulate Ca2+ homeostasis via its role in the parathyroid glands and kidneys. Encaleret was used for the treatment of osteoporosis., but was discontinued in Phase-II in Japan, India and USA in 2011. Uses: The treatment of osteoporosis. Alternative Names: 4-[2-[(1R)-1-[(2R)-3-[[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]ethyl]phenyl]-2-methylbenzoic acid;sulfuric acid;hydrate; JIT305; JIT 305; JIT-305. Grades: 98%. CAS No. 1214922-52-7. Molecular formula: C58H70Cl2F2N2O13S. Mole weight: 1144.16. | |
| Encorafenib | Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine / threonine enzyme in the RAF / mitogen-activated protein kinase kinase (MEK) / extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Alternative Names: LGX818; LGX-818; LGX 818; Methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate. Grades: ≥98%. CAS No. 1269440-17-6. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.011. | |
| Endo-Ala18-Liraglutide | Endo-Ala18-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Alternative Names: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Ala-Lys(Gamma-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C175H270N44O52. Mole weight: 3822.36. | |
| Endo-Gly31-Liraglutide | Endo-Gly31-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Alternative Names: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(Gamma-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-Gly-OH. Molecular formula: C174H268N44O52. Mole weight: 3808.31. | |
| Endo-Gly-AVP | Endo-Gly-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Alternative Names: Di-Gly-Argipressin; Endo-Gly-Vasopressin; Vasopressin, 8-L-arginine-8a-endo-glycine-; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginylglycyl-glycinamide (1->6)-disulfide; Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-Gly-NH2(Cys1&Cys6 bridge); CYFQNCPRGG-NH2(Cys1&Cys6 bridge). Grades: ≥95%. CAS No. 77403-94-2. Molecular formula: C48H68N16O13S2. Mole weight: 1141.29. | |
| ENDOPROTEINASE LYS-C | ENDOPROTEINASE LYS-C. Alternative Names: PROTEASE; EC 3.4.21.50; ENDOPROTEINASE LYS-C; ENDOPROTEINASE LYS-C, LYSOBACTER ENZYMOGENES; endoproteinase lys-C from lysob. enzymog enes 3U / vial (0.1mg; Endoproteinase Lys-C from Lysobacter enzymogenes; Endoproteinase Lys-C, ExcisionGrade; protease from lysoba. CAS No. 72561-05-8. | |
| Endosulfan I | Endosulfan I is a widely used organochlorine insecticide and a stereoisomer of endosulfan II. It is active against a variety of insects, including bollworms. Alternative Names: α-Endosulfan; Endosulfan A; (3α,5aβ,6α,9α,9aβ)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide. Grades: ≥98%. CAS No. 959-98-8. Molecular formula: C9H6Cl6O3S. Mole weight: 406.92. | |
| ENDOTHAL MONOHYDRATE | ENDOTHAL MONOHYDRATE. Alternative Names: 3,6-epoxy-cyclohexan-1,2-dicarboxylic acid; 3,6-Epoxy-cyclohexan-1,2-dicarboxylic acid monohydrate. CAS No. 62059-43-2. Molecular formula: C8H10O5.H2O. | |
| Enfortumab | Enfortumab is a monoclonal antibody targeting Nectin-4. Enfortumab has been used for the treatment of urothelial cancer. CAS No. 1448664-46-7. | |
| Enoxaparin sodium | Enoxaparin sodium is an anticoagulant medication used for the prevention of blood clots such as deep vein thrombosis (DVT), and also for the treatment of blood vessel complications in patients with angina and heart attack. CAS No. 679809-58-6. | |
| Enpatoran | Enpatoran is a potent and orally active dual inhibitor of TLR7/8 with IC50s of 11.1 and 24.1 nM in HEK293 cells, respectively. It blocks molecule synthetic ligands and natural endogenous RNA ligands. It has good pharmacokinetic properties in vivo and can be used to study innate and adaptive autoimmune blocks. Alternative Names: 8-Quinolinecarbonitrile, 5-[(3R,5S)-3-amino-5-(trifluoromethyl)-1-piperidinyl]-; 5-[(3R,5S)-3-Amino-5-(trifluoromethyl)-1-piperidinyl]-8-quinolinecarbonitrile; 5-((3R,5S)-3-Amino-5-trifluoromethylpiperidin-1-yl)quinoline-8-carbonitrile; M 5049; M5049; M-5049. Grades: ≥95%. CAS No. 2101938-42-3. Molecular formula: C16H15F3N4. Mole weight: 320.31. | |
| Enramycin | Enramycin. Alternative Names: Enramicina; Enramycinum; Enramycin[INN]; Enramycinum[INN-Latin]; Enramicina[INN-Spanish]; 12772-37-1. Grades: 95%. CAS No. 12772-37-1. Molecular formula: C107H140Cl2N26O32. Mole weight: 2373.3175. | |
| ent-Cinacalcet Hydrochloride | ent-Cinacalcet Hydrochloride is the (S) enantiomer of Cinacalcet. It is used in clinical trial in secondary hyperparathyroidism. Alternative Names: (αS)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl)propyl]-1-napthalenemethanamine Hydrochloride; (S)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride; (S)-Cinacalcet hydrochloride. Grades: > 95%. CAS No. 694495-47-1. Molecular formula: C22H23ClF3N. Mole weight: 393.87. | |
| Entecavir | An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process. Alternative Names: Baraclude; BMS 200475; BMS-200475; BMS200475; SQ 34676; SQ34676; SQ-34676. Grades: 0.98. CAS No. 142217-69-4. Molecular formula: C12H15N5O3. Mole weight: 277.284. | |
| Entecavir Impurity 5 | An impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Alternative Names: methoxy-(p-methoxytriphenyl)methane; 4.α-Dimethoxy-tritan; methoxy-(4-methoxy-phenyl)-diphenyl-methane; Methoxy-(4-methoxy-phenyl)-diphenyl-methan; Methyl-(4-methoxy-trityl)-aether. Grades: > 95%. CAS No. 84868-56-4. Molecular formula: C21H20O2. Mole weight: 304.39. | |
| Entecavir intermediate,N8 | Entecavir intermediate,N8. Alternative Names: 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine. Grades: 95%. CAS No. 204845-95-4. Molecular formula: C33H33N5O3. Mole weight: 547.65. | |
| ent Efavirenz | ent Efavirenz. Uses: A nonnucleoside hiv-1 reverse transcriptase inhibitor. antiviral. Alternative Names: (4R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (R)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro -4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; L 743725. CAS No. 154801-74-8. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| Enterococcus faecium | Enterococcus faecium. CAS No. 68876-78-8. | |
| Ent-kaurene | Ent-kaurene, a naturally occurring diterpenoid compound, has garnered attention for its potential in combating inflammatory responses and cancerous growth. Moreover, researchers have delved into its ability to modulate plant physiology and phenotypic traits, offering a multifaceted insight into its biological significance. Alternative Names: (±)-Kaura-16-ene. Grades: 98%. CAS No. 562-28-7. Molecular formula: C20H32. Mole weight: 272.48. | |
| ent-Kaurenol | Ent-Kaurenol is a derivative of ent-Kaurane. Ent-Kaurane is an anti-inflammatory found in plants that inhibits various human neutrophil functions. Alternative Names: Kaur-16-en-18-ol; Kaurenol; ent-Kaur-16-en-19-ol; (4α)-Kaur-16-en-18-ol; (-)-Kaur-16-en-18-ol; (-)-Kauren-19-ol. CAS No. 2300-11-0. Molecular formula: C20H32O. Mole weight: 288.47. | |
| Ent-Oseltamivir | Ent-Oseltamivir is an impurity of the antiviral drug oseltamivir, which can be used in COVID19-related research. Alternative Names: (3S,4S,5R)-ethyl 4-acetamido; (3S,4S,5R)-ethyl 4-acetamido-5-amino. CAS No. 1035895-88-5. Molecular formula: C16H28N2O4. Mole weight: 312.40. | |
| Entrectinib | Entrectinib (RXDX-101) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Phase 2. Uses: Protein kinase inhibitors. Alternative Names: RXDX101; RXDX 101; RXDX-101; NMS E628; NMS-E628; Entrectinib; N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide. Grades: ≥98%. CAS No. 1108743-60-7. Molecular formula: C31H34F2N6O2. Mole weight: 560.64. | |
| ent-Rotigotine | ent-Rotigotine is a non-ergot dopamine agonist drug used to treat Parkinson's disease. Alternative Names: 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (6R)-; (6R)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol; 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (R)-; (+)-N 0437; N 0924; (R)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol; (+)-Rotigotine; (R)-Rotigotine. Grades: ≥95%. CAS No. 112835-48-0. Molecular formula: C19H25NOS. Mole weight: 315.47. | |
| Envafolimab | Envafolimab is a recombinant protein of a humanized single-domain anti-PD-L1 antibody. Envafolimab has obtained the U.S. FDA's orphan drug designation for advanced biliary tract cancer. Alternative Names: ASC 22; ASC22; ASC-22; KN 035; KN035; KN-035. CAS No. 2102192-68-5. | |
| Enzalutamide | Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM. It inhibits the activity of prostate cancer cell Ars, which over expressed in prostate cancer. Uses: Potential antineoplastic agent. Alternative Names: MDV3100; MDV 3100; MDV-3100; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide; Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-; 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; S-Enzalutamide; Xtandi. Grades: >98%. CAS No. 915087-33-1. Molecular formula: C21H16F4N4O2S. Mole weight: 464.44. | |
| Enzalutamide Carboxylic Acid | Enzalutamide Carboxylic Acid is a metabolite of Enzalutamide. Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer. Alternative Names: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-benzoic Acid. CAS No. 1242137-15-0. Molecular formula: C20H13F4N3O3S. Mole weight: 451.4. | |
| EOSIN B | EOSIN B. Alternative Names: 4',5'-Dibromo-2',7'-dinitrofluorescein disodium salt; Acid Red 91; Eosin Scarlet; Eosin bluish; Saffrosine. CAS No. 548-24-3. Mole weight: 624.06. | |
| EP4 receptor antagonist 2 | EP4 receptor antagonist 2 (compound 2-13) is a potent antagonist of EP4 receptor with an IC50 of 7.8 nM. Alternative Names: EP4 receptor antagonist; 21965316-82-8; 4-(4-Cyano-2-((2'R,4S)-6-(isopropylcarbamoyl)spiro[chromane-4,1'-cyclopropane]-2'-carboxamido)phenyl)butanoic acid; SCHEMBL17922637BDBM285467. CAS No. 1965316-82-8. Molecular formula: C27H29N3O5. Mole weight: 475.54. | |
| Epacadostat | Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. Alternative Names: IDO inhibitor 1; 1,2,5-Oxadiazole-3-carboximidamide, 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-, [C(Z)]-; [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide; ICBN 24360; ICBN-24360; ICBN24360; INCB 024360; INCB024360; INCB-024360. Grades: ≥95%. CAS No. 1204669-58-8. Molecular formula: C11H13BrFN7O4S. Mole weight: 438.23. | |
| Epalrestat | Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM. Uses: Enzyme inhibitors. Alternative Names: Kinedak; ONO-2235; ONO 2235; ONO2235; Sorbistat; (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (Z,E)-; 3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5Z)-; 2-[(Z)-5-((E)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl]acetic acid; Eabeth. Grades: >98%. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epalrestat (Z,Z)-Isomer | It is a stereoisomer of Epalrestat, an aldose reductase inhibitor with IC50 of 72 nM. Alternative Names: 2-[(5Z)-5-[(2Z)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid; (5Z)-5-[(2Z)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid; 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (Z,Z)-; 3-Thiazolidineacetic acid, 5-[(2Z)-2-methyl-3-phenyl-2-propenylidene]-4-oxo-2-thioxo-, (5Z)-; (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid. Grades: >95%. CAS No. 124782-63-4. Molecular formula: C15H13NO3S2. Mole weight: 319.40. | |
| Epetraborole HCl | This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Alternative Names: UNII-MM0NZY12FA; MM0NZY12FA;SCHEMBL1980656; CHEMBL3527377;3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol;hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grades: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52. | |
| Epibatidine | (±)-Epibatidine is a potent nicotinic agonist (Ki = 0.02 and 233 nM for α4β2 and α7 nicotinic receptors, respectively). Uses: Analgesic. Alternative Names: Epibatidine; (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane. CAS No. 140111-52-0. Molecular formula: C11H13ClN2. Mole weight: 208.69. | |
| Epiberberine | The anti-adipogenic effect of Epiberberine is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte differentiation. Uses: Anti-adipogenic. Alternative Names: epiberberine; 11,12-Dihydro-8,9-dimethoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium; Epiberberine Chloride; BerbiniuM. Grades: >98%. CAS No. 6873-9-2. Molecular formula: C20H18NO4. Mole weight: 336.36. | |
| Epicellobiose | Epicellobiose. Alternative Names: 4-O-β-D-Glucopyranosyl-D-mannopyranose; Mannopyranose, 4-O-β-D-glucopyranosyl-, D-; beta-D-glucosyl-(1->4)-D-mannopyranose; beta-D-glucopyranosyl-(1->4)-D-mannopyranose; D-Glucosyl-D-mannose; (3S,4R,5S,6R)-6-(Hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol. Grades: ≥95%. CAS No. 27452-49-9. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| epi-Lactose | epi-Lactose is an epimer of Lactose and is also known to exhibit prebiotic properties. Alternative Names: 4-O-β-D-galactopyranosyl-D-mannose; 4-O-β-D-galactopyranosyl-mannose; Epilactose. Grades: 98%. CAS No. 50468-56-9. Molecular formula: C12H22O11. Mole weight: 342.30. | |
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