BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Furosemide EP Impurity A | Furosemide EP Impurity A is an impurity of Furosemide. Furosemide is a medication used to treat fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. Alternative Names: Furosemide Related Compound A; Iso Furosemide; 2-Chloro-4-(furfurylaMino)-5-sulfaMoylbenzoic Acid; Isolasix; 5-(Aminosulfonyl)-2-chloro-4-[(2-furanylmethyl)amino]benzoic Acid; H 20. Grades: > 95%. CAS No. 4818-59-1. Molecular formula: C12H11ClN2O5S. Mole weight: 330.75. |  |
| Fursultiamine | Fursultiamine is a medication used for the treatment of thiamine deficiency. Alternative Names: Alinamin F; TTFD. Grades: 98%. CAS No. 804-30-8. Molecular formula: C17H26N4O3S2. Mole weight: 398.55. | |
| Fursultiamine hydrochloride | Fursultiamine is a medication used for the treatment of thiamine deficiency. Alternative Names: Fursultiamine HCl; TTFD Hydrochloride; Thiamin Tetrahydrofurfuryl Disulfide Hydrochloride; Thiamine Tetrahydrofurfuryl Disulfide Hydrochloride. CAS No. 2105-43-3. Molecular formula: C17H27ClN4O3S2. Mole weight: 435. | |
| Furylfuramide | Furylfuramide. Alternative Names: 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide; 2-Furanacrylamide, α-2-furyl-5-nitro-; 2-Furanacetamide, α-[(5-nitro-2-furanyl)methylene]-; α-[(5-Nitro-2-furanyl)methylene]-2-furanacetamide; 2-(2-Furyl)-3-(5-nitrofuryl)acrylamide; AF 2; AF 2 (preservative); Furylamide; NSC 44973. Grades: ≥95%. CAS No. 3688-53-7. Molecular formula: C11H8N2O5. Mole weight: 248.19. | |
| Futalosine | A new nucleoside analog, was isolated from a fermentation broth of Streptomyces sp. MK359-NF1. An antibiotic cancer inhibitor. Alternative Names: 3-[1,5,6-Trideoxy-1-(1,6-dihydro-6-oxo-9H-purin-9-yl)-β-D-ribo-heptofuranuronoyl]benzoic Acid. CAS No. 210644-32-9. Molecular formula: C19H18N4O7. Mole weight: 414.37. | |
| Gabapentin Related Material D | Gabapentin Related Material D is a Gabapentin analogue. Alternative Names: 1-[(3-Oxo-2-azaspiro[4.5]dec-2-yl)methyl]cyclohexaneacetic acid; [1-(3-Oxo-2-aza-spiro[4,5]dec-2-ylmethyl)cyclohexyl]acetic Acid; USP Gabapentin Related Compound D; Gabapentin USP RC D. Grades: > 95%. CAS No. 1076198-17-8. Molecular formula: C18H29NO3. Mole weight: 307.44. | |
| Gadoteric acid | Gadoteric acid is a macrocycle-structured gadolinium-based MRI contrast agent (GBCA). It is used for imaging of blood vessels. Alternative Names: Gadoterate; DOTA-Gd; Gd-Dota; Gadolinium 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetic acid. Grades: 95%. CAS No. 72573-82-1. Molecular formula: C16H25GdN4O8. Mole weight: 558.65. | |
| Gadoteridol | Gadoteridol is a gadolinium-based MRI contrast agent which is commonly used in central nervous system imaging. It is sold under the brand name ProHance. Uses: Gadoteridol is a mri contrast agent that commonly used in central nervous system imaging. Alternative Names: [10-(2-Hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-N1,N4,N7,N10,O1,O4,O7,O10]gadolinium; 1,4,7,10-Tetraazacyclododecane Gadolinium deriv.; 10-(2-Hydroxypropyl)-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Gadolinium Complex; (10-(2-Hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato)gadolinium; GD-HP-DO 3A; Gadolinium-HP-DO 3A; Gadoteridol; ProHance; SQ 32692. Grades: 95%. CAS No. 120066-54-8. Molecular formula: C17H29GdN4O7. Mole weight: 558.68. | |
| Galactan - from gum arabic | Galactan, derived from gum arabic, a vital compound widely used in the biomedical industry. This natural polysaccharide has been extensively used for studying various diseases, including cancer and gastrointestinal disorders. CAS No. 39300-87-3. | |
| Galactoarabinan | Galactoarabinan is a dietary fiber composed of arabinose and galactose monosaccharides. Arabinogalactan can stimulate natural killer (NK) cell cytotoxicity, enhance other functional aspects of the immune system, and inhibit the metastasis of tumor cells to the liver. Nutritional supplement in health care products. Uses: Ingredient of health care products. Alternative Names: D-Galacto-L-arabinan; L-Arabino-D-galactan; ActiFibe; Arabinogalactan fiberaid AG99; FiberAid; Galactoarabinan; HBN; LaraCare; ResistAid. CAS No. 9036-66-2. Molecular formula: ([C5H8O4][C6H10O5]6)x. | |
| galacto-Dapagliflozin | Galacto-Dapagliflozin potently inhibits human SGLT2 (Ki = 2 nM) which is 1,000-fold less potent at human SGLT1 (Ki = 25,000). Alternative Names: (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-galactitol. Grades: ≥95%. CAS No. 1408245-02-2. Molecular formula: C21H25ClO6. Mole weight: 408.9. | |
| Galactooligosaccharides | Galactooligosaccharides are plant sugars linked with chains, which are identified as prebiotics. It stimulates the beneficial bacteria and positively influences the immune system. Nutritional supplement in health care products. Uses: Ingredient of health care products. Alternative Names: GOS. | |
| Galactostatin bisulfite | Galactostatin bisulfite, an exceptional biomedical product, emerges as a targeted intervention against the rampant overexpression of galactose in specific ailments. Its distinctive molecular configuration affords it the capacity to selectively impede the enzymatic process accountable for galactose amalgamation, proffering promising avenues for managing galactosemia and other galactose-linked afflictions. Alternative Names: Galactonojirimycin bisulfite; 5-Amino-5-deoxy-D-galactopyranose; 6-(Hydroxymethyl)-2,3,4,6-peperidinetetrol hydrogensulfite. CAS No. 1196465-02-7. Molecular formula: C6H13NO7S. Mole weight: 243.24. | |
| Galactosyl Cholesterol | Galactosyl Cholesterol is a compound used in research related to lysosomal storage disorders, particularly in the study of Gaucher disease. It plays a role in cellular metabolism and lipid storage, making it a valuable tool for investigating disease mechanisms and potential therapeutic strategies. Alternative Names: β-D-Galactosyl cholesterol. Grades: >99%. CAS No. 51704-23-5. Molecular formula: C33H56O6. Mole weight: 548.79. | |
| Galactosylglycerol | Galactosylglycerol is a natural product found in Capsicum annuum, Homo sapiens, and other organisms. Alternative Names: 3-beta-D-Galactosyl-sn-glycerol; 3-O-beta-D-Galactopyranosyl-sn-glycerol; (2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside. CAS No. 16232-91-0. Molecular formula: C9H18O8. Mole weight: 254.23. | |
| Galactosyl queuosine | Galactosyl queuosine is a biomedical product used for the research of various diseases such as cancerous tumors and infectious diseases. Alternative Names: galQ; O-5''-β-D-galactosylqueuosine; 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[[(1S,4S,5R)-5-(β-D-galactopyranosyloxy)-4-hydroxy-2-cyclopenten-1-yl]amino]methyl]-3,7-dihydro-7-β-D-ribofuranosyl-; (1R,2S,5S)-2-({[2-Amino-4-oxo-7-(β-D-ribofuranosyl)-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]methyl}amino)-5-hydroxy-3-cyclopenten-1-yl β-D-galactopyranoside; 2-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-((((1S,4S,5R)-4-hydroxy-5-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclopent-2-en-1-yl)amino)methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; beta-D-galactosylqueuosine. Grades: ≥95%. CAS No. 60426-58-6. Molecular formula: C23H33N5O12. Mole weight: 571.54. | |
| Galantaminone | Galantamine is a competitive and reversible cholinesterase(AChE) inhibitor, which is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments. Alternative Names: (-)-Narwedine; Narwedin. Grades: >98%. CAS No. 510-77-0. Molecular formula: C17H19NO3. Mole weight: 285.34. | |
| Galega officinalis, ext. | Galega officinalis, ext. Grades: 95%. CAS No. 84650-07-7. | |
| Galeterone | Galeterone (TOK-001 or VN/124-1) is a novel antiandrogen under development by Tokai Pharmaceuticals for the treatment of prostate cancer. It possesses a unique dual mechanism of action, acting as both anandrogen receptor antagonist and an inhibitor of CYP17A1, an enzyme required for the biosynthesis of theandrogens. Alternative Names: TOK-001; TOK 001; TOK001; NX41765; NX 41765; NX-41765; VN 124; VN124; VN-124; VN/124-1; (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol. Grades: >98%. CAS No. 851983-85-2. Molecular formula: C26H32N2O. Mole weight: 388.555. | |
| GALL | GALL. CAS No. 8008-63-7. Molecular formula: C24H40O5. Mole weight: 408.60. | |
| Galloflavin | Galloflavin is a novel inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 μM, respectively). It has also been shown to be a potential anticancer agent. Alternative Names: NSC 107022; 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione. Grades: ≥98%. CAS No. 568-80-9. Molecular formula: C12H6O8. Mole weight: 278.2. | |
| GalNAc C3 CPG | GalNAc-C3-CPG, a novel therapeutic agent, holds significant potential in the fight against viral infections. Its innovative and intricate architecture aptly mimics viral RNA, thereby facilitating the activation of the immune system and a consequential robust antiviral response. Alternative Names: GalNAc C3 CPG 1000Å; (4-(Trimethoxytrityloxymethyl)-1-(6-(4-(3,4,6-O-triacetyl-2-acetylamino-2-deoxy-β-D-galactopyranosyl)butanamido)hexanoyl)piperidin-4-yl)methyl-O-succinoyl CPG. | |
| Galnac GLS-15 | GalNAc GLS-15 is a novel GalNAc-derived small molecule structure designed for siRNA delivery. It is engineered to leverage the high affinity of GalNAc for the asialoglycoprotein receptor (ASGPR) on hepatocytes, enabling efficient liver-targeted delivery of siRNA molecules. This compound is part of the broader GalNAc delivery system, which has been widely adopted for RNA interference (RNAi) therapies due to its ability to enhance drug uptake and reduce off-target effects. Alternative Names: GLS15; GalNAc GLS-15. Grades: >98%. CAS No. 2920438-06-6. Molecular formula: C82H132N11O37P. Mole weight: 1894.97. | |
| GalNAc-INF7 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Alternative Names: GalNAc-CGLFEAIEGFIENGWEGMIDGWYG. Molecular formula: C189H303N39O70S2. Mole weight: 4305.78. | |
| GalNac-L96 analog | GalNAc-L96 analog is an intermediate used in the synthesis of ligands targeting the asialoglycoprotein receptor (ASGPR), a receptor highly expressed on hepatocytes and involved in the internalization and degradation of desialylated glycoproteins. It features a triantennary GalNAc (N-acetylgalactosamine) structure designed to enhance the targeting and delivery of nucleic acid drugs to liver cells. It is commonly used in the development of GalNAc-siRNA conjugates, which leverage the high affinity of GalNAc for ASGPR to facilitate efficient cellular uptake and endosomal release of siRNA molecules, thereby improving the efficacy of RNA-based therapies. Alternative Names: N-Acetylgalactosamine-L96 analog; GalNAc-L96; N-acetyl-D-Galactosamine-L96 analog; (2S,4R)-2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxy-λ-oxo-N-[2-[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]-1,1-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]ethyl]-1-pyrrolidinedodecanamide. Grades: ≥95%. CAS No. 1159408-72-6. Molecular formula: C117H175N11O42. Mole weight: 2407.69. | |
| GalNAc-L96-CPG | GalNAc-L96-CPG is a solid support reagent designed for the synthesis of GalNAc-conjugated oligonucleotides, particularly siRNA, for targeted delivery applications. It consists of a triantennary GalNAc ligand (specifically the L96 variant) covalently attached to a controlled pore glass (CPG) support via a linker. The GalNAc moiety serves as a high-affinity ligand for the asialoglycoprotein receptor (ASGPR), which is abundantly expressed on hepatocytes, enabling efficient receptor-mediated endocytosis of the conjugated oligonucleotide into liver cells. This system facilitates the development of RNA interference (RNAi) therapeutics, such as GalNAc-siRNA conjugates, by enhancing cellular uptake and pharmacokinetic properties. Alternative Names: 3'-GalNAc CPG 1000; GalNAc-L96 CPG. | |
| GalNac-L96 free base | GalNAC-L96 free base is a triantennary GalNAc ligand that can be used for the synthesis of GalNAC-SiRNA and for the delivery of nucleic acid drugs. GalNAc is a ligand for the asialal glycoprotein receptor (ASGPR). Alternative Names: L-96; Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester; 1-[(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] butanedioate; GalNAc-L96-SA; L-96-Succinic Acid; GalNAc-L96-Succinate. Grades: 98%. CAS No. 1159408-61-3. Molecular formula: C121H179N11O45. Mole weight: 2507.76. | |
| GalNAc-L96 Linker-Acid | GalNAc-L96 Linker-Acid is a specialized chemical compound designed for the synthesis of targeted nucleic acid delivery systems. It features a triantennary GalNAc (N-acetylgalactosamine) cluster linked to a longer PEG-based linker, terminating with a carboxylic acid group. This structure allows for efficient conjugation to oligonucleotides, such as siRNA, enabling targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). The compound is widely used in the development of RNA interference (RNAi) therapies, particularly for liver-related diseases. This linker is a key intermediate in the synthesis of GalNAc-siRNA conjugates, which have demonstrated superior stability and gene silencing efficiency compared to traditional lipid nanoparticle delivery systems. Alternative Names: 12,19,25-Trioxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacosanoic acid; 1-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4. Grades: ≥97%. CAS No. 1426159-34-3. Molecular formula: C91H148N10O39. Mole weight: 2006.22. | |
| GalNAc-Lipid GL6 | GalNAc-Lipid GL6 is a potent and scalable ligand designed for targeted liver delivery of therapeutic agents, particularly in the context of CRISPR base editing therapies. It features a multi-valent N-acetylgalactosamine (GalNAc) structure that binds specifically to the asialoglycoprotein receptor (ASGPR), enabling efficient uptake by hepatocytes. This ligand is part of the second-generation GalNAc design, which incorporates a lysine-based scaffold and a longer PEG spacer (34-38 units) compared to earlier designs. The combination of a 1,2-O-dioctadecyl-sn-glyceryl (DSG) lipid anchor and the optimized PEG spacer enhances the stability and delivery efficiency of lipid nanoparticles (LNPs) in vivo. In preclinical studies, GalNAc-Lipid GL6 demonstrated superior performance in liver-targeted gene editing compared to other GalNAc ligands, achieving high editing rates in both wild-type and LDLR-deficient mice and non-human primates. This ligand has shown significant potential for non-LDLR-dependent delivery of CRISPR therapies, making it a valuable tool for treating genetic disorders and metabolic diseases. Grades: 98%. | |
| GalNAc-Lipid GL7 | GalNAc-Lipid GL7 is a ligand designed to optimize the delivery of lipid nanoparticles (LNPs) to hepatocytes via non-LDLR (low-density lipoprotein receptor) dependent pathways. It is based on Design 2, which features a lysine scaffold with three GalNAc units attached through a 36-unit PEG linker. The primary goal of GL7 is to evaluate the impact of different lipid anchors on the stability and delivery efficiency of LNPs. Specifically, GL7 incorporates a cholesteryl (Chol) lipid anchor, which was tested alongside other lipid anchors like 1,2-O-dioctadecyl-sn-glyceryl (DSG) and arachidoyl (C20) to assess their effects on ASGPR (asialoglycoprotein receptor) recognition and binding. However, experiments in Ldlr-mice demonstrated that the DSG lipid anchor in GL6 was significantly more effective for liver-targeted gene editing compared to the cholesterol anchor in GL7, with an editing efficiency of 56% for DSG versus 4% for cholesterol. This suggests that GL7, with its cholesterol anchor, is less efficient for non-LDLR-dependent delivery of LNPs to hepatocytes. Grades: ≥98%. | |
| GalNAc-NAG-25 Phosphoramidite | GalNAc-NAG-25 Phosphoramidite is a modified phosphoramidite that incorporates a N-acetylgalactosamine (GalNAc) moiety linked to the NAG component, specifically designed for the synthesis of oligonucleotides. This compound enhances the stability and bioactivity of nucleic acids, particularly in applications involving targeted delivery and therapeutic interventions. Its unique structural features allow for improved interactions with cellular receptors, making GalNAc-NAG-25 Phosphoramidite valuable in the development of glyco-engineered therapeutics and in the field of glycobiology, where carbohydrate-based modifications play a crucial role in biological processes. Alternative Names: NAG-25; NAG 25; NAG25; GalNAc NAG-25 Phosphoramidite; N2-[23-[Bis(1-methylethyl)amino]-26-cyano-1-oxo-4,7,10,13,16,19,22,24-octaoxa-23-phosphahexacos-1-yl]-N-[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-γ-glutamyl-N,N2-bis[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-glutamamide. Grades: ≥95%. CAS No. 2130036-52-9. Molecular formula: C88H145N10O43P. Mole weight: 2062.13. | |
| GalNAc trimer-Cy5.5 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. Cy5.5 (Cyanine-5.5) is a cyanine dye. Alternative Names: GalNAc trimer-Cyanine5.5. Molecular formula: C112H172N13O33. Mole weight: 2228.63. | |
| Galunisertib | Galunisertib is a potent and selective inhibitor of transforming growth factor beta receptor (TGF-βR) kinase. It was shown to inhibit self-renewal of cancer stem cells. Alternative Names: LY 2157299; LY-2157299; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide. Grades: >98%. CAS No. 700874-72-2. Molecular formula: C22H19N5O. Mole weight: 369.428. | |
| gamma-(BBT)-ATP | Gamma-(BBT)-ATP is a potent and selective inhibitor used in biomedicine for the treatment of various diseases. It specifically targets adenosine triphosphate (ATP) in the gamma-(BBT) pathway, offering potential therapeutic options for metabolic disorders, neurological conditions, and certain types of cancer. This product plays a critical role in accurately modulating ATP levels to restore cellular homeostasis and improve overall health. Alternative Names: gamma-[2'(2-benzothiazoyl)-6'-hydroxybenzothiazole)-adenosine-5'-triphosphate sodium salt. Grades: 95%. Molecular formula: C24H22N7O13P3S2·xNa. Mole weight: 773.52 (free acid). | |
| gamma-Carotene | gamma-Carotene. CAS No. 472-93-5. Molecular formula: C40H56. Mole weight: 536.90. | |
| GAMMA-L-GLU-D-ALA | GAMMA-L-GLU-D-ALA. Alternative Names: GAMMA-L-GLU-D-ALA; H-GLU(D-ALA-OH)-OH; H-GAMMA-GLU-D-ALA-OH. Grades: 95%. CAS No. 42592-56-3. Molecular formula: C8H14N2O5. Mole weight: 218.21. | |
| gamma-Lumicolchicine | gamma-Lumicolchicine is a novel and potent isomer of ultraviolet degradation products of colchicine. Alternative Names: Colchicine Impurity G; γ-Lumicolchicine; [7S-(7α,7bα,10aα)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide; N-[(7S,7bS,10aR)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide. Grades: ≥95%. CAS No. 6901-14-0. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| gamma-METHYL DECALACTONE | gamma-METHYL DECALACTONE, a complex chemical compound utilized within the fragrance sector, exhibits promising potential for treating neurological disorders. Preclinical research demonstrates its neuroprotective capabilities, suggesting possible benefits in combating neurodegenerative conditions. Its multifaceted properties make it a fascinating subject for further exploration and clinical investigation. Alternative Names: 2(3H)-Furanone, 5-hexyldihydro-5-methyl-, 4-Methyl-4-decanolide, 4-Methyldecanolide, 5-Hexyldihydro-5-methyl-2(3H)-furanone, 5-Hexyldihydro-5-methylfuran-2(3H)-one, Dihydrojasmone lactone, gamma-METHYL DECALACTONE, gamma-Methyldecalactone, Lactone of dihy. Grades: 96.0%. CAS No. 7011-83-8. Molecular formula: C11H20O2. Mole weight: 184.27. | |
| gamma-Oryzanol | Gamma-oryzanol is a natural compound found in crude rice bran oil. It acts as a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. Uses: Hair care; body care; face care. Alternative Names: Cycloartenyl ferulate; gamma Oryzanol; Oliver; Gammariza. Grades: 95%. CAS No. 11042-64-1. Molecular formula: C40H58O4. Mole weight: 602.89. | |
| gamma-propanol | gamma-propanol. Alternative Names: 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)-1-propanol;36294-23-2;2,6-di-tert-butyl-4-(3-hydroxypropyl)phenol;AC1L54DJ;Ambcb5319912;Oprea1_629023. Grades: 95%. CAS No. 36294-23-2. Molecular formula: C17H28O2. Mole weight: 264.40302. | |
| gamma-Terpineol | gamma-Terpineol. Grades: 90% by HNMR. CAS No. 586-81-2. Molecular formula: C10H18O. Mole weight: 154.25. | |
| Ganciclovir Diacetyl Impurity | Ganciclovir Diacetyl Impurity is an impurity of Ganciclovir. Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. Alternative Names: 2-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl diacetate; 9-(1,3-diacetate-2-propoxymethyl)guanine; Ganciclovir Impurity 10. CAS No. 86357-19-9. Molecular formula: C13H17N5O6. Mole weight: 339.31. | |
| Ganciclovir Triphosphate | Ganciclovir Triphosphate, a nucleotide analogue possessing antiviral properties, is a prescribed medication for the management of CMV retinitis among individuals with immunodeficiency disease caused by human immunodeficiency virus (HIV). This nucleoside reverse transcriptase inhibitor subdues the activity of viral DNA polymerase and causes interference with viral DNA processing. Ganciclovir Triphosphate, a prodrug dependent on cellular kinases, undergoes conversion into its active metabolite, Ganciclovir Triphosphate. Uses: Antiviral agents. Alternative Names: 9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-Triphosphate; DHP-GTP; GCV-TP. Grades: ≥95% by AX-HPLC. CAS No. 86761-38-8. Molecular formula: C9H16N5O13P3. Mole weight: 495.20. | |
| Ganglioside GD1a (Porcine Brain) | Ganglioside GD1a (Porcine Brain) is a remarkable bioactive lipid molecule used for studying neurodegeneration, specifically Alzheimer's and Parkinson's afflictions. Alternative Names: Disialoganglioside-GD1a (porcine brain, diammonium salt); Ganglioside GD1a; Ganglioside B1; Ganglioside G3; Ganglioside GII; GD1a. Grades: >99%. CAS No. 12707-58-3. Molecular formula: C84H154N6O39. Mole weight: 1872.14. | |
| Ganglioside GD3 ammonium salt | Ganglioside GD3 ammonium salt is used for experimental studies on cancer therapy, especially for melanoma. Shows potential for inducing tumor cell death and inhibiting tumor growth. May also have applications in neurobiological research due to its role in neural development and function. Alternative Names: GD3 Ganglioside (Milk, Bovine-Ammonium Salt). Grades: >99%. CAS No. 1246353-20-7. Molecular formula: C70H131N5O29. Mole weight: 1506.8. | |
| Ganglioside GM1 | Ganglioside GM1 is a specific and only receptor for cholera toxin which facilitates the toxin's transmembrane movement. Cells which lack Ganglioside GM1 can be toxin-resistant, further proving the role of this receptor in the cholera toxicity mechanism. Alternative Names: GM1 Ganglioside (Brain, Ovine-Sodium Salt); Ganglioside GM1; Ganglioside G4; Ganglioside A2; Ganglioside GGtet1; Ganglioside GI; Ganglioside GM1a; Ganglioside M1; GM1; GM1-Ganglioside; Monosialotetrahexosylganglioside; Sialosylganglio-N-tetraosylceramide; Sygen; Galβ1-3GalNAcβ1-4-[NeuAcα1-3]Galβ1-4Glcβ-Cer. Grades: >99%. CAS No. 37758-47-7. | |
| Ganglioside-Total (ammonium salt) | Gangliosides are glycosphingolipids with sialic acid residues in the glycan chain. They are mainly present on the surface of neuronal cells and also present in serum. Four complex ganglioside structures, such as GM1, GD1a, GD1b and GT1b are the most abundantly found ganglioside in mammalian brains. Alternative Names: Total Ganglioside Extract (Brain, Porcine-Ammonium Salt). Grades: >99%. CAS No. 383907-71-9. Molecular formula: C73H134N4O31. Mole weight: 1563.85. | |
| Ganirelix Impurity F | Ganirelix Impurity F is an impurity of Ganirelix Acetate. Alternative Names: AC-D-2-NAL-D-4-CLPHE-D-3-PAL; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanine. Grades: > 95%. CAS No. 129225-22-5. Molecular formula: C32H31ClN4O5. Mole weight: 587.08. | |
| Ganitumab | Ganitumab is a human monoclonal antibody that targets IGF-1R. Ganitumab binds to and inhibits IGF-1R, which plays a key role in cell growth and proliferation. Ganitumab has been used in the research of cancer therapy. Alternative Names: AMG 479; AMG-479; AMG479. Grades: 95%. CAS No. 905703-97-1. Molecular formula: C6472H10028N1728O2020S42. Mole weight: 145.7 kDa. | |
| GANT-61 | GANT 61 is a GLI antagonist that inhibits GLI1 activation of gene expression with an IC50 value of 5 μM. Alternative Names: GANT61; GANT-61; GANT 61; NSC 136476; NSC136476; NSC-136476; 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline. Grades: >98%. CAS No. 500579-04-4. Molecular formula: C27H35N5. Mole weight: 429.612. | |
| Garamine | Garamine is a remarkably potent compound extensively utilized in the research of diverse diseases such as cancer and autoimmune disorders. Alternative Names: 2-Deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl]-D-streptamine. Grades: ≥ 98%. CAS No. 49751-51-1. Molecular formula: C13H27N3O6. Mole weight: 321.374. | |
| Garcinia Cambogia Extract | Garcinia cambogia extract is derived from the fruit of the Garcinia cambogia tree, native to Southeast Asia. The active compound in the extract is flavonoids, polyphenols, and hydroxycitric acid (HCA), which is believed to contribute to its weight loss and appetite-suppressing effects. HCA is thought to inhibit an enzyme called citrate lyase, which plays a role in fat production, thus potentially reducing the accumulation of fat in the body. Additionally, Garcinia cambogia extract is believed to increase serotonin levels in the brain, which can help reduce appetite and improve mood. The extract also has anti-inflammatory, antioxidant, and antibacterial properties, which may support overall health by reducing inflammation and oxidative stress. Garcinia cambogia extract is commonly used in weight management supplements, where it is promoted for its potential to assist in fat loss and improve metabolism. While it is widely used for its weight-loss benefits, further research is needed to fully confirm its effectiveness. Uses: Anti-obesity agents. Alternative Names: Garcinia extract; Garcinia cambogia, ext.; Garcenia cambogia. Grades: 95%. CAS No. 90045-23-1. | |
| Garcinol | Garcinol is an inhibitor of PCAF and p300 histone acetyltransferase (HAT) activity (IC50 = 5 and 7 μM, respectively), which is isolated from Garcinia indica. It also inhibits the HAT GCN5 in Cryptococcus neoformans. Garcinol promotes expansion of human HSCs ex vivo. It induces apoptosis in some cancer cells thus can be used as a cancer therapy. Alternative Names: Camboginol; (1R,5R,7R)-3-(3,4-Dihydroxybenzyol)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione. Grades: ≥98% by HPLC. CAS No. 78824-30-3. Molecular formula: C38H50O6. Mole weight: 602.8. | |
| Gardenia blue | Gardenia blue. Grades: 95%. CAS No. 106441-42-3. | |
| Gardenia yellow | Gardenia Yellow is extracted from the gardenia fruit of Rubiaceae plant. It can be used in fruit juice-flavored beverages, wines, pastries, etc. It has anti-atherosclerosis and hypolipidemic effect. Alternative Names: AYSP 7501; Kuchinashi yellow; Rikecolor Kuchinashi 20. Grades: >98%. CAS No. 94238-00-3. | |
| Garlic oil | Extractives and their physically modified derivatives. Allium sativum, Liliaceae. Alternative Names: Oils, garlic; Allium sativum bulb oil; Allium sativum oil; Garlic oils; Oil of garlic; Oils, Allium sativum bulb oil; Oils, garlic bulb oil; Oleum bulbus allii. CAS No. 8000-78-0. | |
| GAT107 | GAT107 is an allosteric agonist (EC50 value 28 μM) and positive allosteric modulator (PAM) of α7 nicotinic acetylcholine receptors (nAChR). GAT107 is the bioactive enantiomer of 4BP-TQS. It reverses nociception in mouse models of inflammatory and neuropathic pain. Alternative Names: GAT107; GAT-107; GAT 107; (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide. Grades: 99%. CAS No. 1476807-74-5. Molecular formula: C18H17BrN2O2S. Mole weight: 405.31. | |
| GBT-440 | GBT-440 is a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders. Uses: Hematologic agents. Alternative Names: Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011; 2-hydroxy-6-[[2-(2-propan-2-ylpyrazol-3-yl)pyridin-3-yl]methoxy]benzaldehyde; Hemoglobin Modulators-1. Grades: >98%. CAS No. 1446321-46-5. Molecular formula: C19H19N3O3. Mole weight: 337.37. | |
| GD2-Ganglioside | GD2-Ganglioside is a complex lipid molecule extensively present within the neuroblastoma tumours cells. This molecule is the focal point of numerous immunotherapies such as chimeric antigen receptor (CAR) T-cell therapy and monoclonal antibodies and has the ability to specifically recognize and demolish GD2-Ganglioside expressing cancer cells. Alternative Names: Ganglioside GD2; Disialoganglioside-GD2; Disialoganglioside GD2; GD2. CAS No. 65988-71-8. | |
| GD2-Oligosaccharide-sp-biotin | GD2-Oligosaccharide-sp-biotin is a powerful tool used for researching various diseases such as neuroblastoma, melanoma and certain other cancers. It specifically targets GD2 oligosaccharide. The addition of biotin enables efficient detection and purification of GD2 oligosaccharide in experimental settings. Molecular formula: C65H104N10O37SNa2. Mole weight: 1695.61. | |
| GDC-0077 | GDC-0077 is an orally available and selective PI3K inhibitor (IC50 = 0.038 + 0.003 nM) with > 300-fold selective over other Class I PI3K isoforms. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Alternative Names: GDC 0077; GDC0077; Inavolisib. CAS No. 2060571-02-8. Molecular formula: C18H19F2N5O4. Mole weight: 407.37. | |
| GDC-0810 (ARN-810) | GDC-0810, also known as ARN-810 and RG6046, an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robust activity in tamoxifen-resistant breast cancer xenografts. Alternative Names: GDC0810; GDC 0810; GDC-0810; ARN810; ARN 810; ARN-810; RG6046; RG-6046; RG 6046. Grades: 98%. CAS No. 1365888-06-7. Molecular formula: C26H20ClFN2O2. Mole weight: 446.91. | |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Alternative Names: Fenebrutinib; RG 7845; RG7845; GDC0853; RG-7845; GDC 0853; (S)-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one. Grades: 98%. CAS No. 1434048-34-6. Molecular formula: C37H44N8O4. Mole weight: 664.81. | |
| GDC-0994 | GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. Uses: Antineoplastic agents. Alternative Names: GDC0994; GDC 0994; RG7842; RG-7842; RG 7842; Ravoxertinib. CAS No. 1453848-26-4. Molecular formula: C21H18ClFN6O2. Mole weight: 440.863. | |
| GDP-D-glucose disodium salt | GDP-D-glucose sodium salt, a biochemical component for metabolic pathway study and intracellular signaling, plays an imperative role in glucose metabolism. Its potential therapeutic agent property for various diseases is highlighted in recent diabetes and cancer research. And its acknowledged proficiency in regulating the cell differentiation and proliferation further consolidates its prominence. Alternative Names: Guanosine-5-diphosphoglucose disodium salt; GDP-Glc disodium salt; Guanosine 5'-(trihydrogen diphosphate), P'-β-D-glucopyranosyl ester, disodium salt. CAS No. 103301-72-0. Molecular formula: C16H23N5O16P2.2Na. Mole weight: 649.31. | |
| GDP-L-fucose | GDP-L-fucose is a pivotal biomolecule acting as a precursory compound to facilitate the synthesis of fucose-containing glycoconjugates implicated in diverse cellular phenomena. Its exceptional significance lies in the research of glycosylation patterns, evaluation of protein functioning repercussions and investigation into possible therapeutic approaches targeting conditions like cancer and inflammation. Alternative Names: GDP-b-L-fucose; Guanosine 5-diphospho-b-L-fucose; GDP-Fucose; Guanosine diphosphofucose; Guanosine 5'-diphospho-beta-L-fucopyranose; guanosine 5'-[3-(6-deoxy-beta-L-galactopyranosyl) dihydrogen diphosphate]. Grades: 95%. CAS No. 15839-70-0. Molecular formula: C16H25N5O15P2. Mole weight: 589.34. | |
| GDP-L-fucose disodium salt | Substrate for fucosyltransferase. Alternative Names: Guanosine 5'-pyrophosphate, β-L-fucopyranosyl ester Disodium Salt; Guanosine pyrophosphate, L-fucosyl ester Disodium Salt; Guanosine diphosphofucose Disodium Salt; Guanosine diphosphate fucose Disodium Salt; Guanosine 5'-pyrophosphate, L-fucosyl ester Disodium Salt; Guanosine 5'-diphospho-β-L-fucose Disodium Salt; GDP-Fucose Disodium Salt. Grades: ≥95%. CAS No. 148296-47-3. Molecular formula: C16H23N5O15P2Na2. Mole weight: 633.31. | |
| GDP-L-galactose sodium salt | GDP-L-galactose sodium salt, an indispensable element in the field of biomedicine, assumes a pivotal function in the amalgamation of Vitamin C, thereby facilitating the amelioration of scurvy and associated ailments. This efficacious product showcases its potential in enhancing general well-being and mitigating deficiencies stemming from insufficient levels of Vitamin C. Alternative Names: Guanosine 5-diphosphate-L-galactose. Grades: 95%. CAS No. 6815-91-4. Molecular formula: C16H23N5Na2O16P2. Mole weight: 649.30. | |
| Gefitinib-based PROTAC 3 | Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R). Alternative Names: N-[3-(2-{[5-({4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl}oxy)pentyl]oxy}ethoxy)propanoyl]-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide; L-Prolinamide, N-[3-[2-[[5-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]pentyl]oxy]ethoxy]-1-oxopropyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-; Iressa-based PROTAC 3; Gefitinib-based Proteolysis-targeting Chimera 3. Grades: ≥95%. CAS No. 2230821-27-7. Molecular formula: C47H57ClFN7O8S. Mole weight: 934.51. | |
| Gefitinib Impurity VI | Gefitinib Impurity VI is Gefitinib intermediate. Alternative Names: 4-(3-Chloropropyl)morpholine; 1-Chloro-3-morpholinopropane; 3-(Morpholin-4-yl)propyl Chloride; 3-Chloro-1-(morpholin-4-yl)propane; 3-Morpholinopropyl Chloride; NSC 28831; NSC 38889; N-(3-Chloropropyl)morpholine. Grades: > 95%. CAS No. 7357-67-7. Molecular formula: C7H14ClNO. Mole weight: 163.65. | |
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