BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Prosapogenin is a bioactive compound derived from plants like Panax ginseng, known for its potential therapeutic properties. It is a precursor to ginsenosides, which are responsible for many of the health benefits associated with ginseng extracts. Prosapogenin A, one of the key forms of this compound, has been studied for its ability to induce GSDME-dependent pyroptosis, a form of programmed cell death, which may have implications in cancer treatment. In addition to its potential anti-cancer effects, prosapogenin is also explored for its adaptogenic and immunomodulatory properties, similar to those found in Panax ginseng extracts. These properties make it a promising candidate for further research in areas such as stress management, immune support, and overall health enhancement. Alternative Names: Prosapogenin (Ginseng); Panax Ginseng extract; American ginseng P.E. Grades: American ginseng saponins: 20%. CAS No. 50647-08-0.
p-Rosolic acid
p-Rosolic acid. Alternative Names: 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, Aurin. CAS No. 603-45-2. Molecular formula: C19H14O3. Mole weight: 290.31.
Prostaglandin E1
Prostaglandin-E1 is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It can be used as a vasodilator agent increasing peripheral blood flow. Uses: The treatment of erectile dysfunction, vasodilator agent. Alternative Names: l-PGE1; l-Prostaglandin E1; Lipoprost; Liprostin; Minprog; NSC 165559; ONO 1608; PGE-1; Promostan; Prostaglandin E1; Prostandin; Alprostadil; Topiglan; Vasaprostan. U 10136; U-10,136. Grades: 95%~105% (Assay). CAS No. 745-65-3. Molecular formula: C20H34O5. Mole weight: 354.48.
Prostaglandin E2
Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Uses: Endogenous prostaglandin and primary product of arachidonic acid / cyclooxygenase pathway. Alternative Names: Dinoprostone; PGE2; Prostin E2; Prepidil; Cervidil; Minprostin E2; l-Prostaglandin E2. Grades: 95%. CAS No. 363-24-6. Molecular formula: C20H32O5. Mole weight: 352.47.
Prostaglandin F2α tromethamine salt
Prostaglandin F2α is a naturally-occurring prostaglandin and potent vasoconstrictor, exhibiting luteolytic activity. Uses: Abortifacient agents, nonsteroidal. Alternative Names: U 14585; U14585; U-14585; Dinoprost tromethamine salt; Dinolytic; Zinoprost; Prostin F2 alpha. Grades: ≥98%. CAS No. 38562-01-5. Molecular formula: C20H34O5.C4H11NO3. Mole weight: 475.62.
Prostaglandin H1
Prostaglandin H1 (PGH1) is a COX metabolite of DGLA and is the precursor to all 1-series PGs and thromboxanes. PGH1 is a suicide inhibitor of platelet thromboxane synthase with Ki value of 28 μM. Alternative Names: PGH1; 9S,11R-epidioxy-15S-hydroxy-13E-prostaenoic acid; 9alpha,11alpha-epidioxy-15(S)-hydroxy-13-trans-prostenoic acid. Grades: ≥95%. CAS No. 52589-22-7. Molecular formula: C20H34O5. Mole weight: 354.5.
Prostaglandin I2
Prostaglandin I2 is a prostaglandin used primarily to treat pulmonary arterial hypertension (PAH) by relaxing blood vessels and increasing blood flow to the lungs, thereby reducing the workload on the heart. Alternative Names: (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid; 6(9)-Oxy-11,15-dihydroxyprosta-5,13-dienoic acid; Epopreostenol; Epoprostenol; PGI2; PGX; PGX (prostaglandin); Prostacyclin; Prostaglandin X; U 53217; Vasocyclin. Grades: >95%. CAS No. 35121-78-9. Molecular formula: C20H32O5. Mole weight: 352.47.
Prostratin
Prostratin is an activator of protein kinase C (PKC) and also an activator of nuclear factor KB (NF-KB) mediated through activation of the IKKs (IKB kinases). It is an unusual non-tumorigenic phorbol ester and is found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). It has potential to be useful in the treatment of HIV as it could flush viral reservoirs in latently infected CD4+ T-cells. It exhibits promising therapeutic potential against other diseases such as cancer and Alzheimer's disease. It inhibits growth and induces differentiation of AML cell lines. It inhibits tumorigenesis in KRAS mutant pancreatic cancer cells and reduces tumor growth in mouse pancreatic tumor models. Uses: Prostratin has potential to be useful in the treatment of hiv. it exhibits promising therapeutic potential against other diseases such as cancer and alzheimer's disease. Alternative Names: 12-Deoxyphorbol-13-acetate; SA 101A; 13-O-Acetylphorbol. Grades: 95%. CAS No. 60857-08-1. Molecular formula: C22H30O6. Mole weight: 390.47.
PROTAC AR Degrader-4
PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs). Alternative Names: (5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl (14S,17S,18R)-18-amino-17-hydroxy-14-isobutyl-13,16-dioxo-19-phenyl-3,6,9-trioxa-12,15-diazanonadecanoate; Androstan-3-one, 17-[[(14S,17S,18R)-18-amino-17-hydroxy-14-(2-methylpropyl)-1,13,16-trioxo-19-phenyl-3,6,9-trioxa-12,15-diazanonadec-1-yl]oxy]-, (5α,17β)-; (5α,17β)-17-[[(14S,17S,18R)-18-Amino-17-hydroxy-14-(2-methylpropyl)-1,13,16-trioxo-19-phenyl-3,6,9-trioxa-12,15-diazanonadec-1-yl]oxy]androstan-3-one. CAS No. 1351169-31-7. Molecular formula: C43H67N3O9. Mole weight: 770.01.
PROTAC Bcl-xL degrader-3
It is a potent BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Alternative Names: 753b; (2S,4R)-1-((S)-2-(8-(4-(((R)-4'-chloro-4-methyl-6-((4-(4-(((4-(((R)-4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)carbamoyl)phenyl)piperazin-1-yl)methyl)-2,3,4,5-tetrahydro-[1,1'-biphenyl]-4-yl)methyl)piperazin-1-yl)-8-oxooctanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide. CAS No. 2471970-60-0. Molecular formula: C82H105ClF3N11O11S4. Mole weight: 1641.49.
PROTAC BRD4 Degrader-15
PROTAC BRD4 Degrader-15 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4, with IC50s of 7.2 and 8.1 nM for BRD4 BD1 and BD2, respectively. It effectively degrades the BRD4 protein in PC3 prostate cancer cells. Alternative Names: N-(2-(3-amino-5-(2-(2-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)ethyl)phenoxy)ethyl)-7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxamide; N-{[2-(3-Amino-5-{2-[({7-(3,5-difluoro-2-pyridinyl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulen-9-yl}carbonyl)amino]ethoxy}phenyl)ethoxy]acetyl}-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide; L-Prolinamide, N-[2-[2-[3-amino-5-[2-[[[7-(3,5-difluoro-2-pyridinyl)-3,4,6,7-tetrahydro-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-2H-2,4,7-triazadibenz[cd,f]azulen-9-yl]carbonyl]amino]ethoxy]phenyl]ethoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-. CAS No. 2417370-67-1. Molecular formula: C57H62F2N10O10S2. Mole weight: 1149.29.
PROTAC CDK9 degrader-2
PROTAC CDK9 degrader-2 is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin (CDK ligand) binds ubiquitin E3 ligase Cereblon (CRBN) via a linker to form PROTAC. Alternative Names: 1H-1,2,3-Triazole-1-octanamide, 4-[[(5,7-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-8-yl)oxy]methyl]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-; 8-(4-{[(5,7-Dihydroxy-4-oxo-2-phenyl-4H-chromen-8-yl)oxy]methyl}-1H-1,2,3-triazol-1-yl)-N-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]octanamide; 4-[[(5,7-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-8-yl)oxy]methyl]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1H-1,2,3-triazole-1-octanamide. Grades: ≥95%. CAS No. 2435721-30-3. Molecular formula: C39H36N6O10. Mole weight: 748.74.
PROTAC FLT-3 degrader 1
PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1]. IC50: 0.6 nM (FLT-3 ITD). Alternative Names: (2S,4R)-1-[(2S)-2-[3-[2-[2-[2-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]imidazo[2,1-b][1,3]benzothiazol-6-yl]oxyethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. CAS No. 2230826-81-8. Molecular formula: C52H61N9O9S2. Mole weight: 1020.23.
PROTAC K-Ras Degrader-1
PROTAC K-Ras Degrader-1 is potent K-Ras degrader based on Cereblon E3 ligand, exhibits ≥70% degradation efficacy in SW1573 cells. Alternative Names: PROTAC K-Ras Degrader-1; 2378258-52-5; 2-[(2S)-4-[2-[[(2S,4R)-4-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-methylpyrrolidin-2-yl]methoxy]-7-naphthalen-1-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-prop-2-enoylpiperazin-2-yl]acetonitrile; SCHEMBL21459082; EX-A3964; AKOS040740885; MS-31852; HY-129523; CS-0106329; 2-((2S)-1-acryloyl-4-(2-(((2S,4R)-4-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)ethoxy)-1-methylpyrrolidin-2-yl)methoxy)-7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile. Grades: 98%. CAS No. 2378258-52-5. Molecular formula: C53H62N10O10. Mole weight: 999.12.
PROTAC Sirt2 Degrader-1
PROTAC Sirt2 Degrader-1 is a PROTAC selectively targeting on Sirt2, consist an isotype-selective Sirt2 inhibitor SirReal as a warhead linked to cereblon ligand thalidomide. PROTAC Sirt2 Degrader-1 led a selective and dose-dependent degradation of Sirt2 at concentration ranging in 0.2-5μM, as well as a time-dependent depletion of Sirt2 at concentration of 10μM post 0.5-2h with a max degradation observed at 2h in HeLa cells. Depletion of Sirt2 by PROTAC Sirt2 Degrader-1 at concentration of 10μM resulted in a more pronounced acetylation of the microtubule network with enhanced process elongation than enzymatic Sirt2 inhibition. Alternative Names: Sirt2-PROTAC-1; Sirt2 PROTAC-1; Sirt2-PROTAC1; Sirt2 PROTAC 1; N-[4-[4-[[3-[[2-[[2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetyl]amino]-1,3-thiazol-5-yl]methyl]phenoxy]methyl]triazol-1-yl]butyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide. CAS No. 2098487-75-1. Molecular formula: C40H40N10O8S2. Mole weight: 852.94.
Protamine sulfate
Protamine sulfate is used as an antidote against the anticoagulant effects of negatively charged heparin, for example in heart surgery. Alternative Names: Protamines, sulfates; Novo protamine sulfate; Protamine sulfates. CAS No. 9009-65-8.
Protease
Protease. CAS No. 9036-06-0.
Protease type viii bacterial
Protease type viii bacterial. Grades: 95%. CAS No. 9014-1-1.
Protein hydrolysates can be used in culture medium to provide amino acids. Uses: Body care; face care. Alternative Names: Edible gelatine; hydroprot; beviprot; copipor; cutter protein hydrolysate; entomosyl; escoat k; whey protein hydrolysate. CAS No. 9015-54-7.
Protein hydrolyzates, yeast
Protein hydrolyzates, yeast is a hydrolyzed product of yeast cells, which is obtained by autolysis or hydrolysis with additional enzymes. Hydrolyzed yeast products contain a large number of amino acids, small peptides, rich B vitamins, glutathione and nucleotide substances. It is mainly used as an antioxidant in cosmetics and skin care products, controlling oil and resisting fat overflow. Alternative Names: Hydrolyzed yeast protein; Proteins, yeast, hydrolysate; Yeast protein hydrolysate. Grades: 95%. CAS No. 100684-36-4.
Protohypericin
Protohypericin is a quinone isolated from Hypericum perforatum showing photocytotoxicity. Alternative Names: 1,3,4,6,8,15-Hexahydroxy-10,13-dimethyl-dibenzo[a,o]perylene-7,16-dione. Grades: 0.98. CAS No. 548-03-8. Molecular formula: C30H18O8. Mole weight: 506.46.
Protoneogracillin
Protoneogracillin is a furostanol glycoside that has anti-fungal activity against the plant pathogenic fungus P. oryzae (MMDC = 94.0 μM) and cytotoxic activity on K562 cancer cells (IC50 = 6.6 μM). Alternative Names: Protogracillin; (3β,22R,25S)-26-(β-D-Glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-β-D-glucopyranoside; β-D-Glucopyranoside, (3β,22β,25S)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->3)]-. Grades: ≥95%. CAS No. 191334-50-6. Molecular formula: C51H84O23. Mole weight: 1065.20.
Protoporphyrin IX
Created by the enzyme protoporphyrinogen oxidase, protoporphyrin IX is an important precursor to biologically essential prosthetic groups. Uses: Metabolism of porphyrin. Alternative Names: Protoporphyrin; 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid. Grades: ≥95%. CAS No. 553-12-8. Molecular formula: C34H34N4O4. Mole weight: 562.66.
Pro-xylane
Pro-xylane was a xylose originally derived from beech trees, but is now synthesized. Pro-xylane can enhance the binding force of the epidermis and epidermis at the dermal junction (DEJ) by adding the expression of heparan sulfate proteoglycan (HS-PGS)-basement membrane proteoglycan (Perlecan), CD44, and SYNDECANS, and further promote the synthesis of glycosaminoglycan (GAGS) and proteoglycan (PGS). It can make the skin repair firm and moist. It has the effect of anti-aging, removing wrinkles, efficient moisturizing, whitening and lightening spots, firming and repairing, anti-blue light and anti-pollution, and effectively establishing skin protective barrier. It is compatible with cream, gel and water formulations. Alternative Names: Hydroxypropyl tetrahydropyrantriol; Mexoryl SBB; (2S,3R,4S,5R)-2-(2-hydroxypropyl)tetrahydro-2H-pyran-3,4,5-triol; c-beta-d-xylopyranoside-2-hydroxypropane; RelaXin; Puri-Xylane. Grades: ≥98%. CAS No. 439685-79-7. Molecular formula: C8H16O5. Mole weight: 192.21.
Prucalopride
Prucalopride is a potent and selective 5-HT4 receptor agonist. Prucalopride is a gastroprokinetic drug with the brand name Resolor, developed for the treatment of constipation and irritable bowel syndrome. Studies indicates that it is promisingly to be a candidate therapy of Alzheimer's disease and chronic intestinal pseudo-obstruction. Uses: Gastroprokinetic drug. Alternative Names: Resolor; 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide. Grades: 98%. CAS No. 179474-81-8. Molecular formula: C18H26ClN3O3. Mole weight: 367.87.
Prucalopride Impurity 4
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. CAS No. 1599434-55-5. Molecular formula: C17H24ClN3O3. Mole weight: 353.85.
Prucalopride Impurity 6
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Alternative Names: 4-Amino-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide. Grades: > 95%. CAS No. 1608459-56-8. Molecular formula: C18H27N3O3. Mole weight: 333.43.
Prucalopride N-Oxide
A metabolite of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Alternative Names: N-Oxo Prucalopride; 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-1-oxido-4-piperidinyl]-7-benzofurancarboxamide. Grades: > 95%. CAS No. 1900715-98-1. Molecular formula: C18H26ClN3O4. Mole weight: 383.88.
Prucalopride Succinate
A derivative of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Alternative Names: 4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide succinate; R-108512; R 108512; R108512; Prucalopride Succinate; Resolor; Resotran. Grades: > 95%. CAS No. 179474-85-2. Molecular formula: C18H26ClN3O3 C4H6O4. Mole weight: 485.96.
Prulifloxacin
Prulifloxacin prevents bacterial DNA replication, transcription, repair and recombination through inhibition of bacterial DNA gyrase. Uses: Anti-bacterial agents. Alternative Names: NM441; NM 441; NM-441; 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-; 6-Fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid; (±)-7-[4-[(Z)-2,3-Dihydroxy-2-butenyl]-1-piperazinyl]-6-fluoro-1-methyl-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid, cyclic carbonate; Quisnon; Sword. Grades: >98%. CAS No. 123447-62-1. Molecular formula: C21H20FN3O6S. Mole weight: 461.46.
Prunetrin
Prunetrin is a natural flavonoid natural compound with potential pharmaceutical applications in the biomedical industry. Extracted from plants, this product exhibits both antioxidant and anti-inflammatory properties. Alternative Names: Prunetin 4'-O-glucoside. Grades: > 95%. CAS No. 154-36-9. Molecular formula: C22H22O10. Mole weight: 446.40.
Prussian Blue Soluble
Prussian blue is a water-soluble dye used to detect iron in histological tissue sections and biopsy specimens and as a component of Perls Prussian blue. CAS No. 12240-15-2. Molecular formula: C6Fe2KN6.xH2O. Mole weight: 306.89 (anhydrous basis).
Psammaplin A
Psammaplin A. Alternative Names: PsammaplinA; 110659-91-1; Bisprasin; NSC614495; AC1O46WI; SCHEMBL364511. Grades: ≥97%. CAS No. 110659-91-1. Molecular formula: C22H24Br2N4O6S2. Mole weight: 664.39.
PSB 1114
PSB 1114, a β,γ-difluoromethylene derivative of 4-thio-UTP, is a potent, selective P2Y2 agonist (EC50 = 0.134 μM),with >60-fold selectivity versus P2Y4 and P2Y6 receptors. PSB 1114 activated P2Y2, P2Y4 and P2Y6 with EC50 values of 0.134, 9.3 and 7.0 μM respectively. Alternative Names: 4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt; PSB1114; PSB 1114; PSB-1114. Grades: ≥98% by HPLC. CAS No. 1657025-60-9. Molecular formula: C10H11F2N2Na4O13P3S. Mole weight: 622.14.
PSB-SB1202
PSB-SB1202 is a benzylcoumarin compound that acts as an agonist of CB1 and CB2 receptors with EC50 values of 56 and 14 nM, respectively. Alternative Names: 5-Methoxy-3-[(2-methoxyphenyl)methyl]-7-pentylchromen-2-one. Grades: ≥98%. CAS No. 1399049-60-5. Molecular formula: C23H26O4. Mole weight: 366.5.
Pseudaminic acid
Pseudaminic acid is an indispensable compound in the biomedical sector assuming a pivotal involvement in the synthesis of pseudaminic acid capsules, designated for studying bacterial infections resulting from pathogens that express pseudaminic acid-binding proteins. Alternative Names: 5,7-Bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid. Molecular formula: C13H22N2O8. Mole weight: 334.32.
Pseudoacarbose
An impurity of Acarbose, a medication used for the treatment of diabetes mellitus type 2. Alternative Names: (3R,4R,5S,6R)-5-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-(((1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-(hydro. Grades: > 95%. CAS No. 196944-81-7. Molecular formula: C25H43NO17. Mole weight: 645.6.
pseudomonic acid B
An impurity of Mupirocin, an antibiotic used for the treatment of certain skin infections. Alternative Names: (2E)-5,9-Anhydro-2,3,4-trideoxy-8-C-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-D-allo-non-2-enonic Acid 8-Carboxyoctyl Ester; [2E,8[2S,3S(1S,2S)]]-5,9-Anhydro-2,3,4-trideoxy-8-C-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-D-allo-non-2-enonic Acid 8-Carboxyoctyl Ester. Grades: > 95%. CAS No. 40980-51-6. Molecular formula: C26H44O10. Mole weight: 516.63.
Pseudomonic acid F
An impurity of Mupirocin, which is a carboxylic acid bacteriostatic / bactericidal antibiotic. Alternative Names: Mupirocin EP Impurity F; Mupirocin Calcium EP Impurity F; Pseudomonic acid N; Pseudomonic acid F; [2E,8[2S,3S(1S,2S)]]-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid 6-Carboxyhexyl Ester. Grades: > 95%. CAS No. 167842-64-0. Molecular formula: C24H40O9. Mole weight: 472.58.
PseudoUridine 5'-monophosphate
A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Alternative Names: Pseudouridylic acid; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol; pseudouridine 5'-phosphate; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione; 5-b-D-Ribofuranosyluracil 5'-phosphate; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate. Grades: ≥95%. CAS No. 1157-60-4. Molecular formula: C9H13N2O9P. Mole weight: 324.18.
PseudoUridine 5'-Triphosphate
PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock. Alternative Names: Ψ; Pseudo-UTP; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione; 5-β-D-Ribofuranosyluracil 5'-Triphosphate; Pseudouridine Triphosphate; Pseudo UTP; pUTP. Grades: ≥95% by HPLC. CAS No. 1175-34-4. Molecular formula: C9H15N2O15P3. Mole weight: 484.14.
PSI-7976 is an inhibitor of HCV RNA replication with EC50 value of 1.07μM. PSI-7851 is a phosphoramidate prodrug of PSI-7411 and has potent anti-hepatitis C virus (HCV) activity. It is a mixture of two diastereoisomers. PSI-7976 is one of them. Another one is PSI-7977. PSI-7851 is firstly activated through being hydrolyzed by CatA and CES1in the liver cells. It is found that CatA prefers PSI-7977 as a substrate over PSI-7976 while CES1 preferentially hydrolyzes PSI-7976 over PSI-7977. Since CES1 does not express in clone A replicon cells, the ability of PSI-7976 and PSI-7977 to inhibit HCV RNA replication is different in these cells. PSI-7977 is more potent than PSI-7976 with EC50 value of 92nM. Alternative Names: Sofosbuvir (R)-Phosphate; (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. Grades: >98%. CAS No. 1190308-01-0. Molecular formula: C22H29FN3O9P. Mole weight: 529.45.
PSNCBAM-1
PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1 (IC50= 45 and 209 nM) with hypophagic effects in vivo, potentially an anti-obesity agents. Alternative Names: PSNCBAM 1; PSNCBAM1; N-(4-Chlorophenyl)-N'-(3-(6-(1-pyrrolidinyl)-2-pyridinyl)phenyl)urea. Grades: ≥99% by HPLC. CAS No. 877202-74-9. Molecular formula: C22H21ClN4O. Mole weight: 392.88.
Psoralen-C2 CEP
Psoralen-C2 CEP is an innovative biomedical compound, used for studying a myriad of skin afflictions, particularly psoriasand vitiligo. It is derived from psoralen, an organic constituent inherent to select flora. Alternative Names: 2-[4'-(hydroxymethyl)-4,5',8-trimethylpsoralen]-ethyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Psoralen C2 Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]ethyl ester; 2-Cyanoethyl (2-((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methoxy)ethyl) diisopropylphosphoramidite; Psoralen C-2 CED phosphoramidite. Grades: 95%. CAS No. 126221-83-8. Molecular formula: C26H35N2O6P. Mole weight: 502.55.
Psoralen C6 Phosphoramidite
Psoralen C6 Phosphoramidite is an indispensable compound, finding extensive employment in DNA synthesis and modification. This remarkable product effectively facilitates the incorporation of psoralen derivatives into oligonucleotides, thereby enabling the research of an extensive array of afflictions encompassing cancer and dermatological conditions. Alternative Names: 6-[4'-(Hydroxymethyl)-4,5',8-trimethylpsoralen]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester; Psoralen C-6 CED phosphoramidite; 2-Cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester; Psoralen-C6 CEP. CAS No. 518046-08-7. Molecular formula: C30H43N2O6P. Mole weight: 558.65.
PSS-(1-Propylmethacrylate)-Heptaisobutyl substituted is a monomer used to produce coatings in the form of films or beads that are resistant to organic solvents and acids. Alternative Names: Methacryloxypropylheptaisobutyl-T8-silsesquioxane; 3-(3,5,7,9,11,13,15-heptaisobutylpentacyclo[9.5.13,9.15,15.17,13]octasiloxan-1-yl)propylmethacrylate. CAS No. 307531-94-8. Molecular formula: C35H74O14Si8. Mole weight: 943.64.
Psyllium seed gum
Psyllium seed gum comes from plants of the Plantago genus and is cultivated mainly in the Mediterranean and India. It is a soluble dietary fiber. Its structure is a backbone of D-xylopyranosyl units linked (1-4) and (1-3) with the 4-linked units bearing side chains. The side chains consist of α-L-arabinofuranosyl units linked (1-3) and (1-2) and β-D-xylopyranosyl units linked (1-3) and (1-2) and the α-D-Galap-(1-2)-α-L-Rhap aldobiuronic acid units linked (1-2) to the main chain. Uses: Cathartics. Alternative Names: Psyllium gum; Psyllium; Bistop D 2074; Foodmaid P 100; Fudomeido; Gums, psyllium-seed; Healthy Gum; Inagel A 400; Isabgol; Isapol husk mucilage; Isogel; Ispaghule gum; Isubgol; Metamucil; PG 020; PG 200; Plantaben; Plantaglucide; PO Gum; Psyllium mucilloid; RG 500; Soallium PG 200; VIS TOP D 2074; VIS TOP D 2701. Grades: ≥90%. CAS No. 8063-16-9.
PT-2385
PT-2385 is a small molecule inhibitor with oral activity that inhibits hypoxia inducible factor (HIF)-2alpha heterodimerization and its subsequent binding to DNA by binding to HIF-2alpha. Alternative Names: 3-[[(1S)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrilePT-2385; PT2385; PT 2385SCHEMBL165558103-{[(1s)-2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1h-Inden-4-Yl]oxy}-5-Fluorobenzonitrile79A. CAS No. 1672665-49-4. Molecular formula: C17H12F3NO4S. Mole weight: 383.34.
p-Terphenyl is a detector of neutron. It can be used in analytical studies. Uses: Terphenyl mixtures are used as heat transfer media, dye carriers, and in the production of lubricants. Alternative Names: 1,4-diphenylbenzene. Grades: 98%. CAS No. 92-94-4. Molecular formula: C18H14. Mole weight: 230.30.
p-tert-Butoxycarbonyloxystyrene
p-tert-Butoxycarbonyloxystyrene, an important monomer within the biomedical industry, is utilized in the synthesis of copolymers such as poly(styrene-alt-maleic anhydride). Due to its compatibility with therapeutic drugs, these copolymers are currently under investigation as potential therapies for a range of ailments, from cancer to inflammatory disorders. Alternative Names: 1,1-dimethylethyl4-ethenylphenylcarbonate; 4-boc-styrene; c-1566; carbonic acid, 1,1-dimethylethyl 4-ethenylphenylester; TBSM; Tert-butyl 4-vinylphenyl carbonate. Grades: 95%. CAS No. 87188-51-0. Molecular formula: C13H16O3. Mole weight: 220.26.
PTH-DL-HISTIDINE
PTH-DL-HISTIDINE. Alternative Names: PTH-DL-HISTIDINE. CAS No. 66428-49-7. Molecular formula: C13H12N4OS. Mole weight: 272.33.
Pt(II) meso-tetra(pentafluorophenyl)porphine
Pt(II) meso-tetra(pentafluorophenyl)porphine. Alternative Names: PT(II) MESO-TETRA(PENTAFLUOROPHENYL)PORPHINE; 5,10,15,20-TETRAKIS-(2,3,4,5,6-PENTAFLUOROPHENYL)-PORPHYRIN-PT(II); 5,10,15,20-TETRAKIS(PENTAFLUOROPHENYL)-21H,23H-PORPHINE,PLATINUM(II). CAS No. 109781-47-7. Molecular formula: C44H8F20N4Pt. Mole weight: 1167.61.
PTOEP
PTOEP. Alternative Names: RARECHEM AS SA 0081; PT(II) OCTAETHYLPORPHINE; PT(II) OCTAETHYLPORPHINE(PTOEP)2,3,7,8,12,13,17,18-OCTAETHYL-21H,23H-PORPHINE PLATINUM(II); PTOEP; PLATINUM OCTAETHYLPORPHYRIN; Platin(II)octaethylporphine; Pt(II) Octaethylporphine (PtOEP); PtOEP, Platinum(II) 2. Grades: 95%. CAS No. 31248-39-2. Molecular formula: C36H44N4Pt. Mole weight: 727.84.
p-Tolualdehyde
p-Tolualdehyde (CAS# 104-87-0) is a useful synthetic intermediate that can be found in vehicle exhaust emissions, fragrances, flavours and food additives. Alternative Names: 4-methylbenzaldehyde. Grades: 98 %. CAS No. 104-87-0. Molecular formula: C8H8O. Mole weight: 120.15.
p-Toluic acid
p-Toluic acid (CAS# 99-94-5) is a useful research chemical. Alternative Names: 4-methylbenzoic acid. Grades: 95 %. CAS No. 99-94-5. Molecular formula: C8H8O2. Mole weight: 136.15.
p-Tolyl 2,3,4-tri-O-acetyl-a-L-rhamnopyranoside
p-Tolyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranoside is a widely utilized chemical compound in the biomedical sector, manifesting remarkable capabilities in studying a spectrum of ailments, including malignancies and bacterial afflictions. Alternative Names: α-L-Mannopyranoside, 4-methylphenyl 6-deoxy-1-thio-, 2,3,4-triacetate; (2S,3S,4R,5R,6S)-2-Methyl-6-(p-tolylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate; 4-Methylphenyl 6-deoxy-1-thio-α-L-mannopyranoside 2,3,4-triacetate; α-L-Mannopyranoside, 4-methylphenyl 6-deoxy-1-thio-, triacetate. Grades: ≥95%. CAS No. 620951-70-4. Molecular formula: C19H24O7S. Mole weight: 396.46.
p-Tolyl ether
p-Tolyl ether (CAS# 1579-40-4 ) is a useful research chemical. Alternative Names: 1-methyl-4-(4-methylphenoxy)benzene. CAS No. 1579-40-4. Molecular formula: C14H14O. Mole weight: 198.26.
PTZ-343
It acts as an HRP chemiluminescence enhancer. In the configuration of chemiluminescence substrate A/B solution, the addition of a certain amount of enhancer is helpful to enhance the luminescence intensity and sensitivity. Uses: For research use only. Alternative Names: Sodium 3-(10H-Phenothiazin-10-yl)propane-1-sulfonate; 10H-Phenothiazine-10-propanesulfonic Acid, Sodium Salt; 3-(10'-Phenothiazinyl)propane-1-sulfonate Sodium; 3-(phenothiazin-10-yl)propane-1-sulfonate Sodium; PTZ 343; PTZ343. Grades: 98%. CAS No. 101199-38-6. Molecular formula: C15H14NNaO3S2. Mole weight: 343.40.