BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cytosine | Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (anamine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. Synonyms: Cytarabine Impurity C; 4-Aminopyrimidin-2(1H)-one; 6-Amino-2(1H)-pyrimidinone; 4-Amino-1H-pyrimidin-2-one; 4-Amino-2(1H)-pyrimidinone; 4-Amino-2-hydroxypyrimidine; 4-Aminouracil; Gemcitabine EP Impurity A; Lamivudine EP Impurity E; 2-Hydroxy-4-pyrimidinamine; 4-Amino-2-oxo-1,2-dihydropyrimidine; Cytosines; Cytosinimine; NSC 27787; Cytarabine EP Impurity C; Gemcitabine hydrochloride EP Impurity A. Grade: 98%. CAS No. 71-30-7. Molecular formula: C4H5N3O. Mole weight: 111.10. |  |
| Cytosine-[5,6-d2] | Cytosine-[5,6-d2] is an isotope labelled Cytosine, a nucleobase in the synthesis of DNA/RNA. Synonyms: 4-amino-5,6-dideuterio-1H-pyrimidin-2-one; Cytosine-5,6-d2. Grade: 98% atom D. CAS No. 106391-24-6. Molecular formula: C4H3D2N3O. Mole weight: 113.11. | |
| Cytosporone B | Cytosporone B, also called as Csn-B or Dothiorelone G, is the first naturally nuclear orphan receptor Nur77 agonist with an EC50 of 0.278 nM. Synonyms: 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetic acid, ethyl ester; Cytosporone B, Csn-B. CAS No. 321661-62-5. Molecular formula: C18H26O5. Mole weight: 322.4. | |
| Cytostatin | Cytostatin is a potent and selective inhibitor of protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), but it doesn't have effect against PP1, PP2B, or PP5. Synonyms: 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, (5S,6S)-; (5S,6S)-5,6-Dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-2H-pyran-2-one; 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl]-5-methyl-, (5S,6S)-; (+)-Cytostatin; Antibiotic MJ 654NF4; NSC 675266. Grade: ≥75%. CAS No. 682329-63-1. Molecular formula: C21H33O7P. Mole weight: 428.46. | |
| Cytostatin sodium salt | Cytostatin is a potent and selective inhibitor of protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), but it doesn't have effect against PP1, PP2B, or PP5. Synonyms: 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, sodium salt (1:1), (5S,6S)-; 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl]-5-methyl-, monosodium salt, (5S,6S)-; (+)-Cytostatin sodium salt; NSC 675266 sodium salt. Grade: ≥75%. CAS No. 457070-06-3. Molecular formula: C21H32NaO7P. Mole weight: 450.44. | |
| CZ415 | CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Synonyms: CZ415; CZ-415; CZ 415; (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea. CAS No. 1429639-50-8. Molecular formula: C22H29N5O4S. Mole weight: 459.57. | |
| CZC24832 | CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases. Synonyms: CZC24832; CZC-24832; CZC 24832. Grade: 0.98. CAS No. 1159824-67-5. Molecular formula: C15H17FN6O2S. Mole weight: 364.399. | |
| CZC-25146 | CZC-25146 is a compound that acts as an inhibitor of LRRK2, a factor in the expression of Parkinsons. Synonyms: CZC25146; CZC 25146. Grade: >98%. CAS No. 1191911-26-8. Molecular formula: C22H25FN6O4S. Mole weight: 488.54. | |
| CZC-25146 hydrochloride | CZC-25146 is a compound that acts as an inhibitor of LRRK2, a factor in the expression of Parkinsons's disease, and is ATP-competitive. Synonyms: CZC25146 hydrochloride; CZC 25146 hydrochloride. Grade: 0.98. CAS No. 1330003-04-7. Molecular formula: C22H26ClFN6O4S. Mole weight: 524.996. | |
| CZC-54252 | Potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). Attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC50 = 1 nM). Synonyms: CZC-54252; CZC 54252; CZC54252. Grade: >98%. CAS No. 1191911-27-9. Molecular formula: C22H25ClN6O4S. Mole weight: 504.99. | |
| CZC-54252 hydrochloride | CZC-54252 hydrochloride is a potent and selective inhibitor of LRRK2 with IC50s of 1.28 and 1.85 nM for wild-type and G2019S LRRK2, respectively. G2019S LRRK2-induced human neuronal injury is attenuated by CZC-54252 hydrochloride with an EC50 of ~1 nM. It has a neuroprotective activity. Synonyms: Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-, hydrochloride (1:1); N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride. Grade: ≥95%. CAS No. 1784253-05-9. Molecular formula: C22H26Cl2N6O4S. Mole weight: 541.45. | |
| CZC-8004 | CZC-8004 is an aminopyrimidine which is a pan-kinase inhibitor that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. Synonyms: Dianilinopyrimidine-01; CZC-00008004. Grade: ≥98%. CAS No. 916603-07-1. Molecular formula: C17H16FN5. Mole weight: 309.3. | |
| D 106669 | D 106669 is a potent and selective PI3K inhibitor. Synonyms: D-106669; D 106669; D106669; N-ethyl-N'-[3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl]Urea; 3-ethyl-1-{3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl}urea. Grade: 98%. CAS No. 938444-93-0. Molecular formula: C17H18N6O. Mole weight: 322.36. | |
| D-[1-13C;1,1'-2H2]mannitol | D-[1-13C;1,1'-2H2]mannitol. Molecular formula: 13CC52H2H12O6. Mole weight: 185.18. | |
| D-[1-13C]Galacturonic acid potassium salt | D-[1-13C]Galacturonic acid potassium salt. | |
| D13-9001 | D13-9001 is a potent inhibitor of AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) with KDs of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively. It has antibiotic activity. Synonyms: [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate; Ethanaminium, N-(carboxymethyl)-2-[[[[(3R)-1-[8-[[[4-(1,1-dimethylethyl)-2-thiazolyl]amino]carbonyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl]-3-piperidinyl]oxy]carbonyl]amino]-N,N-dimethyl-, inner salt. Grade: ≥95%. CAS No. 957471-96-4. Molecular formula: C31H39N11O6S. Mole weight: 693.78. | |
| D149 Dye | D149 Dye is an organic dye for highly efficient solid-state dye-sensitized solar cells. Uses: D149 dye can be used as an organic dye to enhance the absorption of dye sensitized solar cells (dsscs). Synonyms: D149; D 149; D-149; Indoline dye D149. Grade: >98%. CAS No. 786643-20-7. Molecular formula: C42H35N3O4S3. Mole weight: 741.94. | |
| D2343 | D2343 is a dual inhibitor of β2-adrenoceptor and α1- adrenoceptor. Inhaled D2343 has a longer bronchodilating effect than terbutaline. Synonyms: 4-[1-hydroxy-2-[[4-(2-methoxyphenyl)-2-methylbutan-2-yl]amino]ethyl]phenol; D 2343; D2343; D-2343; N-(3-(2-methoxyphenyl)-1,1-dimethylpropyl)-1-(p-hydroxyphenyl)ethanolamine hydrochloride. CAS No. 72734-63-5. Molecular formula: C20H27NO3. Mole weight: 329.43. | |
| d2-Cefteram | Cefteram metabolite. Synonyms: (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid; T 2525A. Grade: > 95%. CAS No. 104691-34-1. Molecular formula: C16H17N9O5S2. Mole weight: 479.5. | |
| D-2'-Deoxyribofuranosyl-3-guanylurea (α/β-Mixture) | D-2'-Deoxyribofuranosyl-3-guanylurea is used in the synthesis of N4-alkyl-5-azacytidines as mutagenic agents. Synonyms: N-(Aminoiminomethyl)-N-(2-deoxy-D-erythro-pentofuranosyl)urea; Decitabine deformyl impurity formate; Urea, N-(aminoiminomethyl)-N'-(2-deoxy-D-erythro-pentofuranosyl)-; N-(Aminoiminomethyl)-N'-(2-deoxy-D-erythro-pentofuranosyl)urea. Grade: > 95%. CAS No. 570410-72-9. Molecular formula: C7H14N4O4. Mole weight: 218.21. | |
| D-2'-Deoxyribopyranosyl-3-guanylurea (α/β-Mixture) | D-2'-Deoxyribopyranosyl-3-guanylurea (α/β-Mixture) can be obtained from 5-Aza-2'-deoxy Cytidine which can be used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Grade: 98%. Molecular formula: C7H14N4O4. Mole weight: 218.21. | |
| D-(-)-2-Phenylglycine | D-(-)-2-Phenylglycine is the derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. It is also an impurity of Ampicillin and Cefaclor. Synonyms: Ampicillin EP Impurity L; Cefaclor EP Impurity A; (-)-(R)-Phenylglycine; (-)-Phenylglycine; (2R)-Amino-2-phenylethanoic Acid; (R)-(-)-2-Phenylglycine; (R)-2-Amino-2-phenylacetic Acid; (R)-2-Amino-2-phenylethanoic Acid; (R)-2-Phenyl-2-aminoethanoic Acid; (R)-2-Phenylglycine; (R)-2-Phenylglycine. Grade: ≥ 99% (Assay). CAS No. 875-74-1. Molecular formula: C8H9NO2. Mole weight: 151.17. | |
| D-3263 | D-3263 is a TRPM8 agonist ( transient receptor potential melastatin member 8) with potential antineoplastic activity. The active ingredient in enteric-coated TRPM8 agonist D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. This agent may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH. TRPM8 is a transmembrane calcium channel protein that is normally expressed in prostate cells and appears to be overexpressed in benign prostatic hyperplasia (BPH) and in prostate cancer. Synonyms: 3-(2-Aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one; 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-(((1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one. Grade: ≥95%. CAS No. 947257-66-1. Molecular formula: C21H31N3O3. Mole weight: 373.49. | |
| D-3263 hydrochloride | D-3263 hydrochloride is an enteric-coated and orally bioavailable agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity. Synonyms: 3-(2-Amino-ethyl)-1(R)-((2(S)-isopropyl-5(R)-methylcyclohexanecarbonyl))-5-methoxy-1,3-dihydro-benzoimidazol-2-one hydrochloride; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one hydrochloride (1:1); 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, hydrochloride (1:1). Grade: ≥98%. CAS No. 1008763-54-9. Molecular formula: C21H32ClN3O3. Mole weight: 409.95. | |
| D3-βArr | D3-βArr is a positive allosteric modulator of thyrotropin (TSH) receptor. D3-βArr does not activate Beta-Arr 1 translocation to the glucagon-like peptide 1 receptor (GLP-1R) in CHO-K1-GLP1R-Beta Arrestin 1 cells. Synonyms: NCGC00379308; D3-betaArr. CAS No. 662164-09-2. Molecular formula: C20H23N5. Mole weight: 333.4. | |
| d3-Ethyl b-D-glucuronide | d3-Ethyl b-D-glucuronide. Synonyms: 2H3Ethyl-b-D-glucuronide. Molecular formula: C8H11D3O7. Mole weight: 225.21. | |
| D4476 | D4476 is a potent, selective ATP-competitive inhibitor of CK1 (casein kinase 1). Synonyms: Casein Kinase I Inhibitor; D 4476; D-4476. Grade: >98%. CAS No. 301836-43-1. Molecular formula: C23H18N4O3. Mole weight: 398.41. | |
| D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 | D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 is a labelled D-tyrosine. Tyrosine is a non-essential amino acid synthesized from phenylalanine. It is the precursor of some neurotransmitters. Synonyms: D-Tyrosine-d7; p-Hydroxyphenyl-D-alanine-d7; H-D-Tyr-OH-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1426174-46-0. Molecular formula: HOC6D4CD2CD(NH2)COOH. Mole weight: 188.23. | |
| d4TMP | d4TMP, a potent nucleoside analog, is a promising therapeutic agent against various cancers, notably lymphoma and leukemia. Its unique mechanism of action disrupts DNA synthesis, culminating in cancer cell death. Intriguingly, researchers are now exploring the potential of d4TMP in diverse viral afflictions, including HIV and hepatitis B. Synonyms: Stavudine monophosphate, Sodium Salt; 2',3'-Didehydro-2',3'-dideoxythymidine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 3715-64-8. Molecular formula: C10H13N2O7P (free acid). Mole weight: 304.19 (free acid). | |
| d5SICS | d5SICS is a remarkable fluorescent nucleotide analog, harnessed extensively in the realm of DNA sequencing and molecular biology analysis. Exuding its profound impact, this exquisite compound profoundly stimulates DNA polymerase activity and remarkably enhances sequencing accuracy, heralding its excellence in facilitating DNA sequencing, mutation detection and genotyping analysis. Grade: ≥ 97%. CAS No. 1010689-00-5. Molecular formula: C16H17NO3S. Mole weight: 291.37. | |
| D609 | D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor and is antiviral and antitumor agent. It suppresses LPS- and IFNγ-induced NO production and blocks oxidative glutamate toxicity in nerve cells. Synonyms: D-609; D 609; D609; D-609 free. Grade: >98%. CAS No. 83373-60-8. Molecular formula: C11H15KOS2. Mole weight: 266.46. | |
| D-[6-13C]Galacturonic acid potassium salt | D-[6-13C]Galacturonic acid potassium salt. | |
| D-64131 | D-64131, under the IUPAC name (5-methoxy-1H-indol-2-yl)-phenylmethanone, is a 2-aroylindole derivative that inhibits tubulin polymerization. In vitro: Inhibits tumor cell proliferation (IC50 = 74 nM); In vivo: After oral administration, prevents tumor models growing in mice. Synonyms: 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol; 1-(3,4,5-trimethoxyphenyl)-2-(3'-hydroxy-4'-methoxyphenyl)ethene; D-64131; 74588-78-6; (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE; CHEMBL140220; C16H13NO2; (5-methoxy-1H-indol-2-yl)-phenylmethanone; (5-Methoxy-1H-indol-2-yl)(phenyl)methanone; (5-Methoxy-1H-indol-2-yl)-phenyl-methanone; NCGC00025243-01; Tocris-1643; AC1N0QCR; 2-Benzoyl-5-methoxyindole; SCHEMBL5828518; CTK8F8930; DTXSID30397970; ICMIJSRDISNKOC-UHFFFAOYSA-N; HMS3268K07; ZINC2526466; 3570AH; BDBM50107658; AKOS022507157; CS-1008; 2-BENZOYL-5-METHOXY-1H-INDOLE; NCGC00025243-02; AN-25376; HE053371; HE187776; HY-15482; LS-83224; QC-11710; AB0165802; KB-208742; D64131; W-5310; BRD-K26997899-001-01-4; D-64131|(5-Methoxy-1H-indol-2-yl)phenylmethanone. CAS No. 74588-78-6. Molecular formula: C16H13NO2. Mole weight: 251.28. | |
| D75-4590 | D75-4590 is a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor with antifungal activity. Synonyms: Pyrido[1,2-a]benzimidazole-4-carbonitrile, 1-[[2-(diethylamino)ethyl]amino]-2-ethyl-3-methyl-. Grade: 95%. CAS No. 384376-42-5. Molecular formula: C21H27N5. Mole weight: 349.47. | |
| D77 | D77 is anti-HIV-1 inhibitor, which inhibits HIV-1(IIIB) replication (EC50=23.8 μM). Uses: Anti-hiv-1 inhibitor. Synonyms: D77; D 77; D-77; 4-[(5-Bromo-4-{(Z)-[2,4-dioxo-3-(2-oxo-2-phenylethyl)-1,3-thiazolidin-5-ylidene]methyl}-2-ethoxyphenoxy)methyl]benzoic acid. Grade: ≥98%. CAS No. 497836-10-9. Molecular formula: C28H22BrNO7S. Mole weight: 596.44. | |
| D9 | D9 is a thioredoxin reductase (TrxR) inhibitor (EC50 = 2.8 nM, IC50 = 0.03 and 0.1 μM in MCF-7 cells and HT-29 cells, respectively). It exhibits an inhibitory effect on tumor proliferation in vitro and in vivo by inducing cell death. Uses: Antitumor agent. Synonyms: TrxR-IN-D9; D9; (Diphenyl-2-thienylphosphine-κP)[2-(4-methoxyphenyl)ethynyl]gold. Grade: ≥98% by HPLC. CAS No. 1527513-89-8. Molecular formula: C25H20AuOPS. Mole weight: 596.43. | |
| DA-3003-2 | DA-3003-2 is an inhibitor of Cdc25 phosphatase (IC50 = 0.82 μM for human recombinant Cdc25B) and it shows antiproliferative activity. Synonyms: NSC 663285; 7-chloro-6-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione. Grade: ≥98%. CAS No. 383907-47-9. Molecular formula: C15H16ClN3O3. Mole weight: 321.8. | |
| DAA-1106 | DAA-1106, with anxiolytic effects in mice, is a selective ligand for peripheral benzodiazepine receptor (PBR) and a selective agonist at the peripheral benzodiazepine receptor. Synonyms: N-[(2,5-dimethoxyphenyl)methyl]-N-(5-fluoro-2-phenoxyphenyl)acetamide (11C)DAA1106 DAA 1106 DAA-1106 DAA1106 N-(2,5-dimethoxybenzyl)-N-(5-fluoro-2-isophenoxyphenyl)acetamide. CAS No. 220551-92-8. Molecular formula: C23H22FNO4. Mole weight: 395.42. | |
| Dabcyl-5-3-Aminoallyl-2'-dUTP | Dabcyl-5-3-Aminoallyl-2'-dUTP, a modified nucleotide boasting unrivaled capabilities in identifying and assessing DNA sequences. This exceptional molecule dominates the production of DNA microarrays for genotyping and gene expression studies, while showcasing its prowess in sequencing applications. Dabcyl-5-3-Aminoallyl-2'-dUTP's multifaceted skillset further extends to virus and bacteria detection in diagnostic applications. Synonyms: Dabcyl-AA-dUTP. Grade: ≥90% by AX-HPLC. Molecular formula: C27H33N8O15P3. Mole weight: 774.50. | |
| Dabcyl CE Phosphoramidite | Dabcyl CE Phosphoramidite - the quintessential element for producing nucleotide probes. Its significance is pronounced in the life sciences industry due to its implementation in the creation of diagnostic assays that identify microbial and viral infections. It serves a pertinent role in sequencing DNA and researching cancer. Furthermore, it acts as a fluorophore in the development of real-time molecular assays contemplating the detection of diseases such as hepatitis C and HIV. Its optimal physiochemical attributes make it an exceptional reagent for oligonucleotide labeling and sequencing. Grade: >95% by HPLC. Molecular formula: C52H65N6O6P. Mole weight: 901.10. | |
| Dabcyl-dT CEP | Dabcyl-dT CEP is an indispensable entity employed in the realm of biomedical investigation, serving as a pivotal constituent in the synthesis of altered nucleotide analogs. Synonyms: 5'-Dimethoxytrityloxy-5-[(N-4'-carboxy-4-(dimethylamino)-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dabcyl-dT. CAS No. 316121-62-7. Molecular formula: C63H76N9O10P. Mole weight: 1150.32. | |
| Dabigatran | Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Uses: Benzimidazoles; beta-alanine/analogs & derivatives. Synonyms: BIBR 953; BIBR953; BIBR-953. Grade: >98%. CAS No. 211914-51-1. Molecular formula: C25H25N7O3. Mole weight: 471.51. | |
| Dabigatran 2-Acyl Glucuronide-[d3] | Dabigatran 2-Acyl Glucuronide-[d3]. Synonyms: Dabigatran 2-Acyl Glucuronide-d3. Molecular formula: C31H30D3N7O9. Mole weight: 650.65. | |
| Dabigatran 3-acyl glucuronide | Dabigatran 3-acyl glucuronide. Molecular formula: C31H33N7O9. Mole weight: 647.64. | |
| Dabigatran 3-?Amino-?3-?oxopropyl | Dabigatran 3-Amino-3-oxopropyl is an impurity of Dabigatran. Dabigatran is a very potent anticoagulant, in which the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: N-(3-amino-3-oxopropyl)-2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamide; 2-[[[4-(Aminoiminomethyl)?phenyl]?amino]?methyl]?-N-(3-amino-3-oxopropyl)?-1-methyl-N-2-pyridinyl-1H-benzimidazole-5-carboxamide. CAS No. 1643377-48-3. Molecular formula: C25H26N8O2. Mole weight: 470.53. | |
| Dabigatran 4-Acyl Glucuronide | Dabigatran 4-Acyl Glucuronide. Molecular formula: C31H33N7O9. Mole weight: 647.64. | |
| Dabigatran Acyl-β-D-Glucuronide | Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran. It increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran. Synonyms: β-1-O-Acylglucuronide; N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine; β-D-glucopyranuronosyl ester; Dabigatran 1-acylglucuronide. Grade: ≥90%. CAS No. 1015167-40-4. Molecular formula: C31H33N7O9. Mole weight: 647.64. | |
| Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is the major metabolite of Dabigatran in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers). Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine β-D-Glucopyranuronosyl Ester Trifluoroacetic Acid Salt. Grade: ~80%. Molecular formula: C31H33N7O9.x(C2HF3O2). Mole weight: 647.64 + x(114.02). | |
| Dabigatran Acyl-O-2-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-O-2-D-Glucuronide Trifluoroacetic Acid Salt is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-Alanine 2-Ester with β-D-Glucopyranuronic Acid. Molecular formula: C33H34N7O10F3. Mole weight: 761.67. | |
| Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt, is the major human metabolite of Dabigatran, which is an oral anticoagulant from the class of the direct thrombin inhibitors. Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt, is one of the four isomeric acylglucuronides of Dabigatran that were isolated and purified from urine of dosed rhesus monkeys. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-Alanine 2-Ester with β-D-Glucopyranuronic Acid. Molecular formula: C33H34F3N7O11. Mole weight: 761.66. | |
| Dabigatran Acyl-O-3-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-O-3-D-Glucuronide Trifluoroacetic Acid Salt is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine 3-Ester with β-D-Glucopyranuronic Acid. Molecular formula: C33H34N7O10F3. Mole weight: 761.67. | |
| Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt, is the major human metabolite of Dabigatran, which is an oral anticoagulant from the class of the direct thrombin inhibitors. It is one of the four isomeric acylglucuronides of Dabigatran that were isolated and purified from urine of dosed rhesus monkeys. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine 3-Ester with β-D-Glucopyranuronic Acid. Molecular formula: C33H34F3N7O11. Mole weight: 761.66. | |
| Dabigatran Acyl-O-4-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-O-4-D-Glucuronide Trifluoroacetic Acid Salt is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine 4-Ester with β-D-Glucopyranuronic Acid. Molecular formula: C33H34N7O10F3. Mole weight: 761.67. | |
| Dabigatran Acyl-O4-D-Glucuronide Trifluoroacetic Acid Salt | Dabigatran Acyl-O4-D-Glucuronide Trifluoroacetic Acid Salt, is the major human metabolite of Dabigatran, which is an oral anticoagulant from the class of the direct thrombin inhibitors. It is one of the four isomeric acylglucuronides of Dabigatran that were isolated and purified from urine of dosed rhesus monkeys. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine 4-Ester with β-D-Glucopyranuronic Acid. Molecular formula: C33H34F3N7O11. Mole weight: 761.67. | |
| Dabigatran Carboxamide | An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, showing that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: 3-(2-(((4-Carbamoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic Acid; Dabigatran Etexilate Mesylate Impurity D. Grade: ≥95%. CAS No. 2417628-79-4. Molecular formula: C25H24N6O4. Mole weight: 472.49. | |
| Dabigatran Carboxamide Ethyl Ester | Dabigatran Carboxamide Ethyl Ester is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Dabigatran Impurity 74; N-[[2-[[[4-(Aminocarbonyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine Ethyl Ester; Dabigatran Etexilate Mesylate Impurity B. Grade: 98%. CAS No. 1422435-40-2. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| Dabigatran-d3 Ethyl Ester Hydrochloride Salt | Labelled Dabigatran Ethyl Ester derivative. Synonyms: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-(methyl-d3)-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine Ethyl Ester Hydrochloride Salt. Grade: 95%; 99.9% atom D. Molecular formula: C27H26D3N7O3 HCl. Mole weight: 502.58. | |
| Dabigatran Despropionyl Impurity | Dabigatran Despropionyl Impurity is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. CAS No. 1015167-33-5. Molecular formula: C22H21N7O. Mole weight: 399.46. | |
| Dabigatran Etexilate Impurity 1 | An impurity of Dabigatran Ethyl Ester, a nonpeptide, direct thrombin inhibitor. Synonyms: O-Desethyl O-Isopropyl Dabigatran Etexilate. Grade: > 95%. CAS No. 1610758-19-4. Molecular formula: C35H43N7O5. Mole weight: 641.78. | |
| Dabigatran Etexilate Impurity 2 | O-(2-Ethylbutyl) Dabigatran Ethyl Ester is an impurity of Dabigatran Ethyl Ester, a nonpeptide, direct thrombin inhibitor. Synonyms: O-(2-Ethylbutyl) Dabigatran Ethyl Ester; N-[[2-[[[4-[[[(2-Ethylbutoxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-Alanine Ethyl Ester. Grade: > 95%. CAS No. 1610758-20-7. Molecular formula: C34H41N7O5. Mole weight: 627.73. | |
| Dabigatran Etexilate Impurity 5 | Dabigatran Etexilate Impurity 5 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C35H43N7O5. Mole weight: 641.77. | |
| Dabigatran Etexilate Impurity 6 | Dabigatran Etexilate Impurity 6 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C35H42ClN7O5. Mole weight: 676.22. | |
| Dabigatran Etexilate Impurity 7 | Dabigatran Etexilate Impurity 7 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C35H43Cl2N7O5. Mole weight: 712.68. | |
| Dabigatran Etexilate Impurity 8 | Dabigatran Etexilate Impurity 8 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Ethyl N-[(2-{[(4-{N-(chloromethyl)-N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-2-pyridinyl-β-alaninate. Molecular formula: C35H42ClN7O5. Mole weight: 676.22. | |
| Dabigatran Etexilate Impurity 9 | Dabigatran Etexilate Impurity 9 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Molecular formula: C34H41N7O6. Mole weight: 643.75. | |
| Dabigatran etexilate mesylate | Dabigatran etexilate mesylate is the orally active prodrug of dabigatran. It is a reversible and selective, direct thrombin inhibitor (DTI). Synonyms: Ethyl 3-(((2-(((4-(((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1h-benzimidazol-5-yl)carbonyl)(pyridin-2-yl)amino)propanoate, methanesulfonate; Dabigatran etexilate mesylate; BIBR 1048MS; BIBR1048MS; BIBR-1048MS; BIBR 1048; BIBR1048; BIBR-1048; band name: Pradaxa. Grade: >98%. CAS No. 872728-81-9. Molecular formula: C35H45N7O8S. Mole weight: 723.84. | |
| Dabigatran Etexilate N-Oxide Inner Salt | Dabigatran Etexilate N-Oxide is a metabolite of Dabigatran Etexilate, an oral anticoagulant and direct thrombin inhibitor. Synonyms: N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(1-oxido-2-pyridinyl)-β-Alanine Ethyl Ester. Grade: > 95%. CAS No. 1381757-44-3. Molecular formula: C34H41N7O6. Mole weight: 643.73. | |
| Dabigatran Etexilate Propanoate | Dabigatran Etexilate Propanoate is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Propyl 3-(2-(((4-(N-((Hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate; Dabigatran Impurity 38. CAS No. 1304574-20-6. Molecular formula: C35H43N7O5. Mole weight: 641.77. | |
| Dabigatran ethyl AcOH Salt | Dabigatran ethyl AcOH Salt, a remarkable pharmaceutical compound, plays a pivotal role in studying blood clots, encompassing deep vein thrombosand pulmonary embolism. It exerts its profound anticoagulant effects through targeted inhibition of thrombin, a pivotal enzyme in the intricate clotting cascade. Synonyms: Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate acetate. CAS No. 1188263-64-0. Molecular formula: C29H33N7O5. Mole weight: 559.627. | |
| Dabigatran ethyl ester | Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory. Synonyms: β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester; Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate; Ethyl N-((2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-β-alaninate. Grade: >98%. CAS No. 429658-95-7. Molecular formula: C27H29N7O3. Mole weight: 499.56. | |
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