BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Alanine-2-d1 | D-Alanine-2-d1 is a labelled D-Alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Synonyms: (R)-2-Aminopropionic Acid-d1; H-D-Ala-OH-d1; (2R)-2-amino-2-deuteriopropanoic acid. Grade: 95% by HPLC; 98% atom D. CAS No. 56595-54-1. Molecular formula: CH3CD(NH2)COOH. Mole weight: 90.1. |  |
| D-Alanine-3,3,3-d3-N-FMOC | D-Alanine-3,3,3-d3-N-FMOC is a labelled D-Alanine-N-FMOC. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Synonyms: FMOC-D-Alanine-d3; FMOC-D-Ala-OH-d3. Grade: 95% by HPLC; 98% atom D. Molecular formula: CD3CH(NH-FMOC)COOH. Mole weight: 314.35. | |
| D-Alanine-d7 | D-Alanine-d7 is a labelled D-Alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Synonyms: (R)-2-Aminopropionic Acid-d7; H-D-Ala-OH-d7. Grade: 95% by HPLC; 98% atom D. Molecular formula: CD3CD(ND2)COOD. Mole weight: 96.14. | |
| Dalasetron Mesylate hydrate | Dalasetron Mesylate hydrate is a serotonin 5-HT3 receptor antagonist. It is used to treat nausea and vomiting following chemotherapy. Uses: Dalasetron mesylate hydrate is used to treat nausea and vomiting following chemotherapy. Synonyms: rel-(6R,9aS)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate hydrate. Grade: >98 %. CAS No. 878143-33-0. Molecular formula: C20H26N2O7S. Mole weight: 438.49. | |
| Dalcetrapib | Dalcetrapib is a potent CETP inhibitor that increases the HDL level and decreases the VLDL level in plasma. It exhibits cardiovascular protective property. Uses: Anticholesteremic agents. Synonyms: JTT-705; JTT705; JTT 705; RO-4607381; RO4607381; RO 4607381; S-[2-[[1-(2-ethylbutyl)cyclohexanecarbonyl]amino]phenyl] 2-methylpropanethioate. Grade: >98%. CAS No. 211513-37-0. Molecular formula: C23H35NO2S. Mole weight: 389.59. | |
| D-Allitol-13C | Isotope labelled analogue of Allitol, a useful precursor for the production of various L-hexoses. Synonyms: Allit-13C; Allodulcit-13C; Allodulcitol-13C. Molecular formula: C5[13C]H14O6. Mole weight: 183.17. | |
| D-Allono-1,4-lactone | D-Allono-1,4-lactone is a pivotal precursor in the ascorbic acid (vitamin C) synthesis processes, finding extensive utilization in research of vitamin C inadequacy, scurvy and affiliated ailments. Synonyms: D-Allonic acid gamma-lactone. CAS No. 29474-78-0. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| D-Allose,6-(dihydrogen phosphate) | D-Allose,6-(dihydrogen phosphate), a dynamic biomedical substance, is renowned for its efficaciousness in combating specific ailments. Serving as a formidable hindrance to glucokinase, a multifaceted enzyme entangled in numerous metabolic maladies such as type 2 diabetes, this compound boasts an unrivaled chemical configuration that intricately modulates glucose metabolism. Synonyms: 6-O-[Hydroxy(oxo)phosphaniumyl]-D-allose. CAS No. 82259-50-5. Molecular formula: 260.13. Mole weight: 304.10. | |
| D-Allose-6-phosphate disodium | D-Allose-6-phosphate disodium is an indispensable biomolecular compound assuming a paramount role in the research of diverse afflictions, notably those targeting metabolic irregularities and correlated maladies. Synonyms: D-Allose, 6-(dihydrogen phosphate)?, sodium salt (1:2). Grade: 95%. CAS No. 1161976-98-2. Molecular formula: C6H11O9PNa2. Mole weight: 304.10. | |
| D-Allo-Thr(5)-Semaglutide | D-Allo-Thr(5)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: His-Aib-Glu-Gly-D-Allo-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys (AEEAc-AEEAc-γ-Glu-17-carboxy heptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-allo-Thr(6)-Octreotide trifluoroacetate salt | D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Grade: 95%. | |
| D-Allo-Thr(7)-Semaglutide | D-Allo-Thr(7)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe-D-Allo-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Allulose (D-Psicose) | A C3 epimer of L-Fructose. Synonyms: D-Allulose; D-Ribo-2-hexulose. Grade: > 95%. CAS No. 551-68-8. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| Dalotuzumab | Dalotuzumab is a humanized monoclonal antibody that targets IGF-1R. Dalotuzumab has been used in the research of various cancers such as breast cancer, non small cell lung cancer, and metastatic colorectal cancer. Synonyms: MK-0646; MK 0646; MK0646. Grade: 95%. CAS No. 1005389-60-5. Molecular formula: C6528H10086N1730O2018S40. Mole weight: 146.4 kDa. | |
| D-α-(4-Hydroxyphenyl-2,3,5,6-d4)glycine-α-d1 | D-α-(4-Hydroxyphenyl-2,3,5,6-d4)glycine-α-d1 is a labelled D-4-Hydroxyphenylglycine. D-4-Hydroxyphenylglycine is a derivative of glycine. Synonyms: 4-Hydroxy-D-phenylglycine-d1; (R)-α-Amino-4-hydroxyphenylacetic Acid-d1; H-D-Phg(4-OH)-OH-d1. Grade: 95% by HPLC; 98% atom D. Molecular formula: HOC6D4CD(NH2)COOH. Mole weight: 172.19. | |
| D-α-Guloheptonic acid sodium salt | D-α-Guloheptonic acid sodium salt. Synonyms: Glucoheptonic acid, sodium salt, D-; D-Glucoheptonic acid, sodium salt; Sodium glucoheptonate. Grade: 95%. CAS No. 906339-30-8. Molecular formula: C7H13NaO8. Mole weight: 248.16. | |
| D-α-Hydroxyglutaric acid | D-α-Hydroxyglutaric acid is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling. Synonyms: (R)-2-Hydroxyglutarate; (R)-2-Hydroxyglutaric acid; (R)-2-Hydroxypentanedioic acid; D-2-Hydroxyglutaric acid. CAS No. 13095-47-1. Molecular formula: C5H8O5. Mole weight: 148.11. | |
| D-alpha-Tocopherol Succinate | D-alpha-Tocopherol Succinate is the salt form of vitamin E, a class of eight fat-soluble compounds. It was shown to induce apoptosis and inhibit proliferation, and down-regulate the fibroblast growth factor receptor-1 (FGFR1). Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: Vitamin E succinate; Alpha-Tocopheryl succinate; D-; 4-oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid. Grade: 95%. CAS No. 4345-3-3. Molecular formula: C33H54O5. Mole weight: 530.79. | |
| Daltroban | Daltroban is a selective thromboxane A2 receptor antagonist. Synonyms: BM-13505; Daltrobanum; SKF 96148. Grade: 95%. CAS No. 79094-20-5. Molecular formula: C16H16ClNO4S. Mole weight: 353.82. | |
| D-Altrose | D-Altrose is a revered compound, emerging as a promising ally in studying diverse bacterial infections. Demonstrating its multifunctional attributes, it not only serves as a pivotal antibiotic precursor, stimulating their synthesis, but also augments their effectiveness. Moreover, the remarkable inhibitory prowess of D-Altrose against specific pathogenic bacteria endows it with unrivaled potential in studying the menacing antibiotic-resistant strains. Synonyms: D(+)-Altrose; Altrose, D-; aldehydo-D-altrose. CAS No. 1990-29-0. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| dA-Me Phosphonamidite | dA-Me Phosphonamidite - an essential reagent for oligonucleotide synthesis - provides dual functionality as a nucleobase protecting group and methyl group conductor. This versatile reagent has significantly contributed to the development of oligonucleotides with antisense capabilities, showing great promise in combating complex afflictions such as cancer, viral infections, and genetic disorders. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphonamidite. Molecular formula: C45H51N6O6P. Mole weight: 802.91. | |
| DAMGO TFA | DAMGO is a selective peptide agonist of the μ-opioid receptor. Grade: 99%. CAS No. 950492-85-0. Molecular formula: C28H36F3N5O8. Mole weight: 627.61. | |
| D-Amino Acid Oxidase Inhibitor | D-Amino acid oxidase inhibitor is a selective D-amino acid oxidase (DAAO) inhibitor (IC50 = 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively). D-Amino acid oxidase inhibitor (10-200 mg/kg, i.p.) inhibits DAAO activity in rat kidney and cerebellum in a dose- and time-dependent manner. Synonyms: DAAO inhibitor; 4H-thieno[3,2-b]pyrrole-5-carboxylic acid. Grade: ≥98%. CAS No. 39793-31-2. Molecular formula: C7H5NO2S. Mole weight: 167.2. | |
| D-Aminogalacturonic acid | D-Aminogalacturonic acid. Synonyms: D-Galacturonic acid, 2-amino-2-deoxy-; 2-Amino-2-deoxy-D-galacturonic acid; Galacturonic acid, 2-amino-2-deoxy-, D-; 2-Amino-2-deoxygalacturonic acid. CAS No. 14307-17-6. Molecular formula: C6H11NO6. Mole weight: 193.15. | |
| Daminozide | Daminozide is a highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC50 values of 1.5, 0.55, and 2.1 μM, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC50s > 100 μM). Daminozide is known to retard plant growth and was widely used in the 1960s for agricultural and horticultural applications to control plant size and fruit ripening before it was withdrawn because of carcinogenicity concerns. Synonyms: Alar; B 995; DMASA; SADH; Succinic Acid; Aminozide; Kylar; DIMG. Grade: >98%. CAS No. 1596-84-5. Molecular formula: C6H12N2O3. Mole weight: 160.17. | |
| DAMPA Ethyl Ester | DAMPA Ethyl Ester is an analog of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Uses: A methotrexate analog with altered ester group. Synonyms: 4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic Acid Ethyl Ester; Ethyl p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoate; NSC 694477. Grade: ≥95%. CAS No. 43111-51-9. Molecular formula: C17H19N7O2. Mole weight: 353.38. | |
| dAMPαS | dAMPαS is a novel and indispensable biochemical entity functioning as a pivotal precursor for the intricate process of DNA synthesis while concurrently serving as a substrate for a diverse repertoire of enzymes intricately involved in nucleotide metabolism pathways. Synonyms: 2'-Deoxyadenosine-5'-(α-thio)-monophosphate, Sodium salt. Grade: ≥ 97% by HPLC. Molecular formula: C10H14N5O5PS (free acid). Mole weight: 347.29 (free acid). | |
| Danicamtiv | Danicamtiv is an inotropic agent and cardiac myosin activator. Danicamtiv can enhance cardiomyocyte contraction. Synonyms: SAR 440181; MYK-491; MYK 491; MYK491. CAS No. 1970972-74-7. Molecular formula: C16H20F3N5O4S. Mole weight: 435.42. | |
| Danicopan | Danicopan is a potent, selective and orally active factor D inhibitor. Therapeutic FD inhibition was designed to control IVH and prevent C3-mediated extravascular hemolysis (EVH). Synonyms: ACH-0144471; ACH-CFDIS; ALXN 2040; ACH-4471. CAS No. 1903768-17-1. Molecular formula: C26H23BrFN7O3. Mole weight: 580.41. | |
| Daniquidone | Daniquidone, also known as Batracylin, is a water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of daniquidone is highly toxic and is capable of inducing unscheduled DNA synthesis; rapid acetylators are more likely to experience toxicity with this agent. Synonyms: Batracylin; Bay H 2049; NSC-320846; 8-Aminoisoindolo[1,2-b]quinazolin-12(10H)-one. CAS No. 67199-66-0. Molecular formula: C15H11N3O. Mole weight: 249.27. | |
| Danirixin | Danirixin is a small-molecule, selective, reversible, and non-peptide CXCR2 antagonist with high affinity (IC50 for CXCL8 binding = 12.5 nM). Synonyms: GSK1325756; GSK-1325756; GSK 1325756; Danirixin; N-(4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)phenyl)-N'-(3-fluoro-2-methylphenyl)urea. CAS No. 954126-98-8. Molecular formula: C19H21ClFN3O4S. Mole weight: 441.9. | |
| Danofloxacin Mesylate | Danofloxacin is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase. Uses: Anti-infective agents. Synonyms: CP-76136-27. Grade: >98%. CAS No. 119478-55-6. Molecular formula: C19H20FN3O3.CH4O3S. Mole weight: 453.48. | |
| Danoprevir | Danoprevir(ITMN-191;R7227; RO5190591;RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Synonyms: RG7227; RG 7227; RG-7227; ITMN191; ITMN-191; ITMN 191; RO5190591; RO-5190591; RO 5190591. Grade: 0.98. CAS No. 850876-88-9. Molecular formula: C35H46FN5O9S. Mole weight: 731.837. | |
| Dansyl-NECA | Dansyl-NECA is a selective fluorescent adenosine A1 receptor agonist and shows effects in permitting visualization of A1 receptors in the rat cerebellar cortex. Synonyms: Dansyl-NECA; DansylNECA; Dansyl NECA; 1-Deoxy-1-[6-[[6-[[[5-dimethylamino)-1-naphthalenyl]sulfonyl]amino]hexyl]amino]-9H-purin-9-yl]-N-ethyl-β-D-ribofuranuronamide. Grade: ≥99% by HPLC. CAS No. 219982-12-4. Molecular formula: C30H40N8O6S. Mole weight: 640.75. | |
| Dantrolene | Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. Synonyms: Dantrolenum [INN-Latin]; Dantroleno [INN-Spanish]; Dantrolenum; Ryanodex; 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin; Hydantoin, 1-((5-(p-nitrophenyl)furfurylidene)amino)-; 1-(((5-(4-Nitrophenyl)-2-furanyl)methylene)amino)-2,4-imidazolidinedione; 2,4-Imidazolidinedione, 1-(((5-(4-nitrophenyl)-2-furanyl)methylene)amino)-; 833480-90-3; 1-[[5-(p-Nitrophenyl)furfurylidene]amino]hydantoin; 1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione; 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione; 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-. Grade: 99% (HPLC). CAS No. 7261-97-4. Molecular formula: C14H10N4O5. Mole weight: 314.25. | |
| Dantrolene Impurity 2 | 5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone is an impurity in the synthesis of Dantrolene, a muscle relaxant (skeletal). Dantrolene is used in the treatment of malignant hyperthermia. Synonyms: 5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone; [(Aminocarbonyl)[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazino]acetic Acid; Dantrolene Impurity. Grade: > 95%. CAS No. 57268-33-4. Molecular formula: C14H12N4O6. Mole weight: 332.27. | |
| Dantrolene Impurity 3 | 2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester is an intermediate used in the synthesis of 1-(5-Phenylfurfurylideneamino)hydantoins. Synonyms: 2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester. Grade: > 95%. CAS No. 55227-60-6. Molecular formula: C16H16N4O6. Mole weight: 360.32. | |
| Dantrolene Sodium | Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It suppresses the release of calcium previously sequestered by skeletal, but not cardiac, muscle sarcoplasmic reticulum. Synonyms: Dantrolene sodium salt; Dantrium; Sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate. Grade: 98.0%~102.0%. CAS No. 14663-23-1. Molecular formula: C14H9N4NaO5. Mole weight: 336.239. | |
| Dantrolene sodium hemiheptahydrate | Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by blocking excitation-contraction coupling in the muscle fiber. Uses: Muscle relaxants, central. Synonyms: Dantrolene sodium salt; Dantrium; Sodium dantrolene. Grade: ≥99%. CAS No. 24868-20-0. Molecular formula: C14H9N4O5·7/2H2O·Na. Mole weight: 399.29. | |
| Danuglipron | Danuglipron is an orally small-molecule glucagon-like peptide 1 receptor (GLP-1R) agonist. Danuglipron is undergoing clinical trials for the treatment of diabetes. Synonyms: PF-06882961; PF 06882961; PF06882961. Grade: 98% by HPLC. CAS No. 2230198-02-2. Molecular formula: C31H30FN5O4. Mole weight: 555.6. | |
| Danuglipron tromethamine | PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). Synonyms: PF-06882961 tromethamine; PF-06882961 Tris; Danuglipron Tris; 2-((4-(6-(4-cyano-2-fluorobenzyloxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-((2S)-oxetan-2-ylmethyl)-1H-benzimidazole-6-carboxylic acid, (1:1) salt with 2-amino-2-(hydroxymethyl)propane-1,3-diol. CAS No. 2230198-03-3. Molecular formula: C35H41FN6O7. Mole weight: 676.75. | |
| Danusertib | Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed. This agent may preferentially bind to and inhibit Aurora B kinase. Aurora kinases, a family of serine-threonine kinases, are important regulators of cellular proliferation and division. Synonyms: PHA739358; PHA-739358; PHA 739358; Danusertib. CAS No. 827318-97-8. Molecular formula: C26H30N6O3. Mole weight: 474.55. | |
| dAP2 (Nic) | dAP2 (Nic) presents itself as a worthy consideration in cholinergic signaling modulation. Its focus on targeting the nicotinic acetylcholine receptor exhibits prospects for application in treating perturbed signaling ailments like Alzheimer's disease and schizophrenia. Synonyms: P1-[5'-(2'-Deoxy-adenosyl)] P2-[5'-(1-β D-Ribofuranosyl-nicotinamide)] diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C21H27N7O13P2 (free acid). Mole weight: 647.43 (free acid). | |
| D-AP4 | D-AP4 has been found to be an excitatory amino acid receptor antagonist as well as an agonist at the quisqualate-sensitized AP6 site. Synonyms: D-AP4; D AP4; DAP4; D-(-)-2-Amino-4-phosphonobutyric acid. Grade: ≥98% by HPLC. CAS No. 78739-01-2. Molecular formula: C4H10NO5P. Mole weight: 183.10. | |
| D-AP5 | D-AP5, a more active form of AP5, has been found to be an NMDA antagonist. Synonyms: D-(-)-2-Amino-5-phosphonopentanoic acid. Grade: ≥99% by HPLC. CAS No. 79055-68-8. Molecular formula: C5H12NO5P. Mole weight: 197.13. | |
| D-AP7 | D-AP7 is a selective NMDA receptor antagonist that inhibits the glutamate binding site and activation of NMDA receptor. It is the 8-Bromo-cGMP and the more active form of DL-AP7. It shows anticonvulsant and anxiogenic-like effects. Synonyms: Heptanoic acid, 2-amino-7-phosphono-, (2R)-; D-AP7; D(-)-2-Amino-7-phosphonoheptanoic acid; (2R)-2-amino-7-phosphonoheptanoic acid. CAS No. 81338-23-0. Molecular formula: C7H16NO5P. Mole weight: 225.181. | |
| DAP-81 | DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations. Synonyms: DAP81; DAP 81; DAP-81. N-(4-((4-((2-benzoylphenyl)amino)-5-nitropyrimidin-2-yl)amino)phenyl)acetamide. Grade: 98%. CAS No. 794466-17-4. Molecular formula: C25H20N6O4. Mole weight: 468.464. | |
| dA(PAc)-3'-Methoxy Phosphoramidite | dA(PAc)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for oligonucleotide synthesis. The adenine base is protected with a phenoxyacetyl (PAc) group at the N6 position, providing stability and preventing undesired side reactions during synthesis. The 3'-hydroxyl group is substituted with a methoxy group, enhancing the chemical stability and altering the structural properties of the resulting oligonucleotides. The phosphoramidite functionality at the 3' position ensures efficient coupling during automated oligonucleotide synthesis. This modification is particularly useful in applications requiring oligonucleotides with increased stability and resistance to enzymatic degradation, such as in therapeutic nucleic acids, antisense technologies, and advanced molecular biology research. Synonyms: DMT-dA(PAc)-3'-Methoxy Phosphoramidite; 5'-O-DMTr-2'-deoxy-A(PAc)-3'-Methoxy-phosphoramidite; N6-Phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-adenosine-3'-Methoxy-phosphoramidite; dA(PAc) OMe-amidite. Grade: ≥95%. Molecular formula: C46H53N6O8P. Mole weight: 848.94. | |
| Dapagliflozin | Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; BMS 512148. Grade: >98%. CAS No. 461432-26-8. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin 2-O-β-D-glucuronide | Dapagliflozin 2-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-2-O-β-D-glucopyranuronosyl-D-glucitol. Grade: >95%. CAS No. 2078003-84-4. Molecular formula: C27H33ClO12. Mole weight: 585.00. | |
| Dapagliflozin 3-O-β-D-Glucuronide | Dapagliflozin 3-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-, (1S)-; (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; Dapagliflozin M-15 metabolite; Dapagliflozin 3-O-glucuronide. Grade: ≥95%. CAS No. 1351438-75-9. Molecular formula: C27H33ClO12. Mole weight: 585.00. | |
| Dapagliflozin C1,C2 Epimer | Dapagliflozin C1,C2 Epimer is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin C1,C2 Epimer Tetraacetate | Dapagliflozin C1,C2 Epimer Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C29H33ClO10. Mole weight: 577.02. | |
| Dapagliflozin C2 Epimer Tetraacetate | Dapagliflozin C2 Epimer Tetraacetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C29H33ClO10. Mole weight: 577.02. | |
| Dapagliflozin Dimer | Dapagliflozin Dimer is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Sugar Dimer. CAS No. 2452300-79-5. Molecular formula: C42H48Cl2O12. Mole weight: 815.73. | |
| Dapagliflozin Furanose Isomer | Dapagliflozin Furanose Isomer is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin 1,4-Anhydro impurity; (1S)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol. Grade: >95%. CAS No. 1469910-70-0. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin Impurity 1 | Dapagliflozin Impurity 1 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Bromo Keto Impurity; (5-Bromo-2-Chlorophenyl)(2-Ethoxyphenyl)Methanone. Grade: > 95%. CAS No. 1404477-10-6. Molecular formula: C15H12BrClO2. Mole weight: 339.61. | |
| Dapagliflozin Impurity 10 | Dapagliflozin Impurity 10 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Hydroxy Impurity; 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranose. Grade: >90%. CAS No. 960404-86-8. Molecular formula: C21H25ClO7. Mole weight: 424.87. | |
| Dapagliflozin Impurity 11 | Dapagliflozin Impurity 11 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Dimer. Molecular formula: C42H48Cl2O12. Mole weight: 815.73. | |
| Dapagliflozin Impurity 12 | Dapagliflozin Impurity 12 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C18H42O6Si4. Mole weight: 466.86. | |
| Dapagliflozin Impurity 13 | Dapagliflozin Impurity 13 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C21H25ClO6. Mole weight: 408.88. | |
| Dapagliflozin Impurity 14 | Dapagliflozin Impurity 14 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Ent-Dapagliflozin. Molecular formula: C21H25ClO6. Mole weight: 408.87. | |
| Dapagliflozin Impurity 16 | Dapagliflozin Impurity 16 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1α-Methyl Dapagliflozin; Dapagliflozin Methoxy Pyranose Impurity; (2S,3R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methyl 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-; Methoxy Dapagliflozin. Grade: >95%. CAS No. 714269-57-5. Molecular formula: C22H27ClO7. Mole weight: 438.90. | |
| Dapagliflozin Impurity 17 | Dapagliflozin Impurity 17 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1,4-Dibromo-2-[(4-ethoxyphenyl)methyl]benzene. Grade: >95%. CAS No. 1807632-93-4. Molecular formula: C15H14Br2O. Mole weight: 370.08. | |
| Dapagliflozin Impurity 2 | Dapagliflozin Impurity 2 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-bromo-1-chloro-2-(2-ethoxybenzyl)benzene. Grade: >95%. CAS No. 1830346-16-1. Molecular formula: C15H14BrClO. Mole weight: 325.63. | |
| Dapagliflozin Impurity 20 | Dapagliflozin Impurity 20 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-Bromo-1-chloro-2-(4-methoxybenzyl)benzene; 2-(4-methoxybenzyl)-4-bromo-1-chlorobenzene. Grade: >95%. CAS No. 333361-51-6. Molecular formula: C14H12BrClO. Mole weight: 311.6. | |
| Dapagliflozin Impurity 21 | Dapagliflozin Impurity 21 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin Dibromo compound. Molecular formula: C29H33ClO10. Mole weight: 577.02. | |
| Dapagliflozin Impurity 24 | Dapagliflozin Impurity 24 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol; BMS-639432. Grade: >95%. CAS No. 1204222-85-4. Molecular formula: C21H25ClO7. Mole weight: 424.87. | |
| Dapagliflozin Impurity 25 | Dapagliflozin Impurity 25 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C29H33ClO10. Mole weight: 577.02. | |
| Dapagliflozin Impurity 27 | Dapagliflozin Impurity 27 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Molecular formula: C42H48Cl2O13. Mole weight: 831.73. | |
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