BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
A building block for preparing fluorinated spacers having nucleophilic and electrophilic termini. Alternative Names: Boc-1-amino-2-bromoethane; (2-Bromoethyl)-carbamic acid tert-butyl ester. Grades: ≥ 99 % (GLC). CAS No. 39684-80-5. Molecular formula: C7H14NO2Br. Mole weight: 224.09.
Boc-2-aminoindane-2-carboxylic acid
Boc-2-aminoindane-2-carboxylic acid is used to prepare thiol dipeptides as dual inhibitors of angiotensin-I-converting enzyme and neutral endopeptidase. It is also used in the synthesis of bombesin analogs. Alternative Names: Boc-Aic-OH; 2-((tert-Butoxycarbonyl)amino)-2,3-dihydro-1H-indene-2-carboxylic acid; N-BOC-2-AMINOINDANE-2-CARBOXYLIC ACID; 2-(BOC-AMINO)INDANE-2-CARBOXYLIC ACID; 2-[(tert-butoxy)carbonylamino]indane-2-carboxylic acid; BOC AIC OH. Grades: ≥ 98% (HPLC). CAS No. 71066-00-7. Molecular formula: C15H19NO4. Mole weight: 277.32.
Boc-2-cyano-D-phenylalanine. Alternative Names: Boc-D-Phe(2-CN)-OH; Boc-o-Cyano-D-Phe-OH; (R)-Boc-2-amino-(2-cyanophenyl)propanoic acid; Boc-D-2-cyanophenylalanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-cyanophenyl)propanoic acid; Boc-D-2-Cyano phenylalanine; 2-Cyano-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine; (2R)-2-(tert-Butyloxycarbonylamino)-3-(2-cyanophenyl)propanoic acid; Boc O Cyano D Phe OH. Grades: ≥ 99% (HPLC). CAS No. 261380-28-3. Molecular formula: C15H18N2O4. Mole weight: 290.31.
Boc-2-fluoro-D-β-homophenylalanine
Boc-2-fluoro-D-β-homophenylalanine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: (R)-3-((tert-butoxycarbonyl)amino)-4-(2-fluorophenyl)butanoic acid; Boc-D-β-HomoPhe(2-F)-OH; Boc-(R)-3-amino-4-(2-fluorophenyl)butyric acid. Grades: >98%. CAS No. 218608-98-1. Molecular formula: C15H20FNO4. Mole weight: 297.32.
Boc-2-fluoro-D-phenylalanine
Boc-2-fluoro-D-phenylalanine is a useful research chemical for organic synthesis and other chemical processes. Alternative Names: Boc-D-Phe(2-F)-OH; Boc-o-fluoro-D-Phe-OH; (R)-Boc-2-amino-3-(2-fluorophenyl)propionic acid; Boc-D-2-fluorophenylalanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-fluorophenyl)propanoic acid; Boc-Phe(2-F)-OH; N-(tert-butoxycarbonyl)-2-fluoro-D-phenylalanine; D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-2-fluoro-; (R)-2-[(TERT-BUTOXYCARBONYL)AMINO]-3-(2-FLUOROPHENYL)PROPANOIC ACID; (2R)-3-(2-fluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. Grades: ≥ 99% (HPLC). CAS No. 114873-10-8. Molecular formula: C14H18FNO4. Mole weight: 283.30.
Boc--(2-furyl)-D-Ala-OH (dicyclohexylammonium) salt
Boc--(2-furyl)-D-Ala-OH (dicyclohexylammonium) salt. Alternative Names: (R)-2-(Boc-amino)-3-(2-furyl)propionic acid (dicyclohexylammonium) salt, Boc-3-(2-furyl)-D-alanine (dicyclohexylammonium) salt. Grades: ≥98.0% by TLC. CAS No. 331730-09-7. Molecular formula: C24H40N2O5. Mole weight: 436.59.
Boc-2-isothiocyanatoethylamine
Boc-2-isothiocyanatoethylamine (CAS# 137743-46-5) is a useful research chemical. Alternative Names: tert-Butyl N-(2-isothiocyanatoethyl)carbamate; N-Boc-2-isothiocyanatoethylamine. Grades: ≥ 95 % (NMR). CAS No. 137743-46-5. Molecular formula: C8H14N2O2S. Mole weight: 202.28.
Boc-2-Me-D-Ser-Ome
Boc-2-Me-D-Ser-Ome. Alternative Names: Boc 2 Me D Ser Ome; methyl 2-{[(tert-butoxy)carbonyl]amino}-3-hydroxy-2-methylpropanoate. CAS No. 188476-28-0. Molecular formula: C10H19NO5. Mole weight: 233.26.
Boc-2-Me-Ser-OH
Boc-2-Me-Ser-OH. Alternative Names: N-Boc-alpha-methyl-L-serine; Boc 2 Me Ser OH. CAS No. 84311-19-3. Molecular formula: C9H17NO5. Mole weight: 219.23.
Boc-(2S,4S)-4-amino-1-Fmoc-pyrrolidine-2-carboxylic Acid is used to prepare low molecular weight cyclic peptides as inhibitors of SDF-1 binding to CXCR4. It is also used to design α-conotoxin analogs targeting α7 nicotinic acetylcholine receptors. Alternative Names: Boc-(2S,4S)-4-amino-1-Fmoc-pyrrolidine-2-carboxylic acid; (2S,4S)-Boc-4-amino-1-fmoc-pyrrolidine-2-carboxylic acid; 1,2-Pyrrolidinedicarboxylic acid,4-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(9H-fluoren-9-ylmethyl)ester, (2S,4S)-; (4S)-1-Fmoc-4-(Boc-amino)-L-proline; (2S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid. Grades: ≥ 98% (HPLC). CAS No. 221352-74-5. Molecular formula: C25H28N2O6. Mole weight: 452.60.
Boc-3-(1-naphthyl)-L-alanine, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance. Alternative Names: Boc-L-Ala(1-naphthyl)-OH; Boc-(S)-2-amino-3-(naphthalen-1-yl)propanoic acid; Boc-3-(1-naphthyl)-L-alanine; Boc-L-1-naphthylalanine; Boc-1-Nal-OH; (S)-N-Boc-L-(1-naphthyl)alanine; (2S)-2-[(tert-butoxy)carbonylamino]-3-naphthylpropanoic acid; Boc-L-3-(1-Naphthyl)-alanine; Boc L Nal OH. Grades: ≥ 99% (HPLC). CAS No. 55447-00-2. Molecular formula: C18H21NO4. Mole weight: 315.36.
Boc-3-(2-Furyl)-DL-alanine. Alternative Names: 2-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid. CAS No. 870245-94-6. Molecular formula: C12H17NO5. Mole weight: 255.27.
Boc-3-(2-naphthyl)-L-alanine
Boc-3-(2-naphthyl)-L-alanine functions as a reagent for the synthesis of dipeptidyl nitriles as potent and reversible inhibitors of Cathepsin C. Alternative Names: Boc-L-Ala(2-naphthyl)-OH; Boc-2-Nal-OH; N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-L-alanine; Boc-3-(2 naphthyl)-L-alanine; BOC-2-L-NAPHTHYLALANINE; (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(naphthalen-2-yl)propanoic acid; Boc-L-2-Naphthylalanine; N-Boc-3-(2-naphthyl)-L-alanine; (S)-2-((tert-butoxycarbonyl)amino)-3-(naphthalen-2-yl)propanoic acid. Grades: ≥ 99.5% (Chiral HPLC). CAS No. 58438-04-3. Molecular formula: C18H21NO4. Mole weight: 315.36.
Boc-3-(2-naphthyl)-L-alanine Merrifield resin
Boc-3-(2-naphthyl)-L-alanine Merrifield resin. Alternative Names: Boc-L-Ala(2-naphthyl)-Merrifield resin.
Boc-3-(2'-pyridyl)-D-alanine
Boc-3-(2'-pyridyl)-D-alanine is an intermediate used to prepare heterocyclic amides as nitric oxide production inhibitors. Alternative Names: Boc-D-Ala(2'-pyridyl)-OH; (R)-2-tert-Butoxycarbonylamino-3-pyridin-2-yl-propionic acid; Boc-D-2-pyridylalanine; BOC-D-2-PAL-OH; BOC-2'-PYRIDYL-D-ALA; Boc-D-3-(2-pyridyl)-alanine; BOC-D-ALA(2-PYRI)-OH; N-Boc-beta-(2-pyridinyl)-D-alanine; (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-pyridin-2-ylpropanoic acid. Grades: ≥ 99% (HPLC). CAS No. 98266-32-1. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Boc-3-(3'-pyridyl)-D-alanine is an alanine derivative, used in various chemical synthesis and peptide chemistry. Alternative Names: Boc-D-Ala(3'-pyridyl)-OH; Boc-(R)-2-amino-3-(3'-pyridyl)propanoic acid; Boc-D-3-Pyridylalanine; BOC-D-3-PAL-OH; Boc-3-(3-pyridyl)-D-alanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-3-yl)propanoic acid; BOC-D-3-(3-PYRIDYL)-ALANINE; Boc-D-Pal; N-tert-Butoxycarbonyl-3-pyridyl-D-alanine; Boc D Pal. Grades: ≥ 98% (HPLC). CAS No. 98266-33-2. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Boc-3,4-dehydro-D-Valine. Alternative Names: Boc-δ-D-Val-OH. Molecular formula: C10H17NO4. Mole weight: 215.25.
Boc-3,4-dehydro-L-proline
Boc-3,4-Dehydro-L-Proline is an N-terminal protected 3,4-Dehydro-L-proline. It is used in solid-phase peptide synthesis (SPPS) to make peptides. 3,4-Dehydro-L-proline is an alternate substrate of the amino acid oxidase, NikD. Alternative Names: Boc-3,4-dehydro-L-Pro-OH; (S)-Boc-2,5-dihydropyrrole-2-carboxylic acid; (S)-1-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid; BOC-3,4-DEHYDRO-PRO-OH; (2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-2,5-dihydropyrrole-2-carboxylic acid; AK115638; Boc-Delta(3)Pro-OH; Boc-3,4-dehydro-D-proline; N-Boc-3,4-Dehydro-Pro-OH. Grades: ≥ 98% (HPLC). CAS No. 51154-06-4. Molecular formula: C10H15NO4. Mole weight: 213.23.
Boc-3,4-dichloro-D-phenylalanine is used to prepare fluorinated β-aminoacyl 1,2,4-triazolo[4,3-a]piperazine amides as dipeptidyl peptidase IV inhibitors and antidiabetic agents. It is also used in the synthesis of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide as a potent and orally active dual neurokinin NK1/NK2 receptor antagonist. Alternative Names: Boc-D-Phe(3,4-DiCl)-OH; Boc-D-Phe(3,4-Cl2)-OH; (R)-Boc-2-amino-3-(3,4-dichlorophenyl)propionic acid; Boc-D-Phe(3,4-Cl2)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid; D-Phenylalanine, 3,4-dichloro-N-[(1,1-dimethylethoxy)carbonyl]-; Boc-D-3,4-Dichlorophenylalanine; AK162594; N-BOC-3,4-DICHLORO-D-PHENYLALANINE. Grades: ≥ 98% (HPLC). CAS No. 114873-13-1. Molecular formula: C14H17Cl2NO4. Mole weight: 334.20.
Boc-3,4-difluoro-D-beta-homophenylalanine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: Boc-(R)-3-amino-4-(3,4-difluoro-phenyl)-butyric acid; (R)-3-((tert-butoxycarbonyl)amino)-4-(3,4-difluorophenyl)butanoic acid. Grades: >90%. CAS No. 269396-59-0. Molecular formula: C15H19F2NO4. Mole weight: 315.31.
Boc-3,4-difluoro-DL-phenylalanine
A reactant in the preparation of amino acid derivatives as melanocortin receptor ligands. Alternative Names: Boc-3,4-difluoro-DL-phenylalanine; Boc-3,4-difluoro-DL-Phe-OH; (RS)-Boc-2-amino-3-(3,4-difluorophenyl)propionic acid. Grades: ≥ 99% (HPLC). CAS No. 1214041-87-8. Molecular formula: C14H17F2NO4. Mole weight: 301.30.
Boc-3,4-difluoro-D-phenylalanine
Boc-3,4-difluoro-D-phenylalanine is used in the discovery of pyrrolopyrimidine inhibitors of Akt as antitumor agents. Alternative Names: Boc-D-Phe(3,4-DiF)-OH; Boc-3,4-difluoro-D-Phe-OH; (R)-Boc-2-amino-3-(3,4-difluorophenyl)propionic acid; BOC-d-3,4-Difluorophenylalanine; Boc-D-Phe(3,4-F2)-OH; boc-d-phe(3,4-dif)-oh; N-(tert-Butoxycarbonyl)-3,4-difluoro-D-phenylalanine; D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-3,4-difluoro-; J-300395; (r)-2-(tert-butoxycarbonylamino)-3-(3,4-difluorophenyl)propanoic acid; (2R)-3-(3,4-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. Grades: ≥ 98% (HPLC). CAS No. 205445-51-8. Molecular formula: C14H17F2NO4. Mole weight: 301.29.
Boc-3-(4'-pyridyl)-L-alanine is the protected form of L-Alanine, a non-essential amino acid that can be found naturally in the human body and is obtained by our diet. Alternative Names: Boc-L-Ala(4'-pyridyl)-OH; Boc-(S)-2-amino-3-(4'-pyridyl)propanoic acid; Boc-L-4-Pyridylalanine; Boc-Ala(4-pyridyl)-OH; Boc-3-(4-pyridyl)-L-alanine; Boc-4-Pal-Oh; (S)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid; N-(tert-butoxycarbonyl)-3-pyridin-4-yl-L-alanine; Boc-L-3-(4-pyridyl)-alanine. Grades: ≥ 99.5% (Chiral HPLC). CAS No. 37535-57-2. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Boc-3,5-diiodo-L-tyrosine N-hydroxysuccinimide ester is a boc-protectected amino acid used in the synthesis of peptides and peptide fragments, such as analogs of α-factor, the Saccharomyces cerevisiae tridecapeptide mating pheromone. Alternative Names: Boc-3,5-diiodo-L-Tyr-OSu; Boc-Tyr(3,5-I2)-OSu; (S)-2,5-Dioxopyrrolidin-1-yl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3,5-diiodophenyl)propanoate; (2,5-dioxopyrrolidin-1-yl) (2S)-3-(4-hydroxy-3,5-diiodophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate; N-[(1,1-dimethylethoxy)carbonyl]-3,5-diiodo-L-Tyrosine 2,5-dioxo-1-pyrrolidinyl ester; [(1S)-2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1-[(4-hydroxy-3,5-diiodophenyl)methyl]-2-oxoethyl]-Carbamic acid 1,1-dimethylethyl ester; (S)-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1-[(4-hydroxy-3,5-diiodophenyl)methyl]-2-oxoethyl]-Carbamic acid 1,1-dimethylethyl ester; 2-tert-Butoxycarbonylamino-3-(4-hydroxy-3,5-diiodophenyl)-propionic acid 2,5-dioxopyrrolidin-1-yl ester. Grades: ≥ 98% (HPLC). CAS No. 163679-35-4. Molecular formula: C18H20I2N2O7. Mole weight: 630.33.
Boc-3-amino-3-methylbutyric acid. Alternative Names: 3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid. Grades: 95%. CAS No. 129765-95-3. Molecular formula: C10H19NO4. Mole weight: 217.26.
Boc-3-aminobenzoic acid
Boc-3-aminobenzoic acid, is an intermediate in the synthesis of various pharmaceutical compounds, including inhibitors, and therapeutic agents. It can also be used in the preparation of conformationally-constrained cyclic peptides with biarylamine linkers. Alternative Names: Boc-3-Abz-OH; 3-(Boc-amino)benzoic acid; 3-(Boc-amino)benzoic acid; BOC-3-AMINOBENZOIC ACID; 3-(BOC-AMINO)-BENZOIC ACID; 3-(tert-butoxycarbonylamino)benzoic acid; Benzoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-; 3-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid; Boc 3 Abz OH. Grades: ≥ 99% (HPLC). CAS No. 111331-82-9. Molecular formula: C12H15NO4. Mole weight: 237.25.
Boc-(3-aminomethyl) benzoic acid
Boc-(3-aminomethyl) benzoic acid (CAS# 117445-22-4) is used to synthesize aminodihydroquinazolines as inhibitors of BACE-1 (β-site APP cleaving enzyme). It is also used to prepare spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. Alternative Names: Boc-3-Amb-OH. Grades: ≥ 98 % (HPLC). CAS No. 117445-22-4. Molecular formula: C13H17NO4. Mole weight: 251.27.
Boc-3-benzothienyl-D-alanine
A useful research chemical for organic synthesis and other chemical processes. Alternative Names: Boc-3-D-Ala(3-benzothienyl)-OH. Grades: ≥ 99 % (HPLC). CAS No. 111082-76-9. Molecular formula: C16H19NO4S. Mole weight: 321.4.
Boc-3-benzothienyl-L-alanine
Boc-3-benzothienyl-L-alanine. Alternative Names: Boc-3-L-Ala(3-benzothienyl)-OH. Grades: ≥ 99% (HPLC). CAS No. 154902-51-9. Molecular formula: C16H19NO4S. Mole weight: 321.39.
Boc-3-chloro-D-phenylalanine
Boc-3-chloro-D-phenylalanine. Alternative Names: Boc-D-Phe(3-Cl)-OH; Boc-m-chloro-D-Phe-OH; (R)-Boc-2-amino-3-(3-chlorophenyl)propionic acid. Grades: ≥ 99% (HPLC). CAS No. 80102-25-6. Molecular formula: C14H18ClNO4. Mole weight: 299.75.