BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Curvalicin-28b | Curvalicin-28b is an antibacterial peptide isolated from Lactobacillus curvatus. It has activity against gram-positive bacteria. Alternative Names: Bioactive peptide 1; BAP2. Molecular formula: C52H72N10O12. Mole weight: 1158.55. |  |
| Curvalicin-28c | Curvalicin-28c is an antibacterial peptide isolated from Lactobacillus curvatus. It has activity against gram-positive bacteria. Alternative Names: Bioactive peptide 3; BAP3; Asn-Ile-Pro-Gln-Leu-Thr-Pro-Thr-Pro. Grades: 97.7%. Molecular formula: C44H73N11O14. Mole weight: 980.13. | |
| Curvaticin | Curvaticin is an antibacterial peptide isolated from Lactobacillus curvatus. It has activity against gram-positive bacteria. Alternative Names: Ala-Tyr-Pro-Gly-Asn-Gly-Val-His-Cys-Gly-Lys-Tyr-Ser-Cys-Thr-Val-Asp-Lys-Gln-Thr-Ala-Ile-Gly-Asn-Ile-Gly-Asn-Asn-Ala-Ala. Molecular formula: C127H199N39O43S2. Mole weight: 3024.33. | |
| CXCR301 | CXCR301. Molecular formula: C36H47N9O6. Mole weight: 701.80. | |
| Cy5, β-Amyloid (1-42) | Cy5, β-Amyloid (1-42). Alternative Names: Cy5-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala. Mole weight: 5152.83. | |
| Cy-AMP1 | Cy-AMP1 is a plant defensin isolated from Cycas revoluta. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Lys-Gly-Ala-Pro-Cys-Ala-Lys-Lys-Pro-Cys-Cys-Gly-Pro-Leu-Gly-His-Tyr-Lys-Val-Asp-Cys-Ser-Thr-Ile-Pro-Asp-Tyr-Pro-Cys-Cys-Ser-Lys-Tyr-Gly-Phe-Cys-Gly-Ser-Gly-Pro-Gln-Tyr-Cys-Gly. Molecular formula: C198H290N52O58S8. Mole weight: 4583.34. | |
| Cy-AMP2 | Cy-AMP2 is a plant defensin isolated from Cycas revoluta. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Lys-Gly-Gly-Pro-Cys-Ala-Lys-Lys-Pro-Cys-Cys-Gly-Pro-Leu-Gly-His-Tyr-Lys-Val-Asp-Cys-Ser-Thr-Ile-Pro-Asp-Tyr-Pro-Cys-Cys-Ser-Lys-Tyr-Gly-Phe-Cys-Gly-Ser-Gly-Pro-Gln-Tyr-Cys-Gly. Molecular formula: C197H288N52O58S8. Mole weight: 4569.31. | |
| Cyanophlyctin | Cyanophlyctin is an antibacterial peptide isolated from Euphlyctis cyanophlyctis. It has activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: Phe-Leu-Asn-Ala-Leu-Lys-Asn-Phe-Ala-Lys-Thr-Ala-Gly-Lys-Arg-Leu-Lys-Ser-Leu-Leu-Asn. Grades: 96.4%. Molecular formula: C108H183N31O27. Mole weight: 2347.83. | |
| Cyclic L27-11 | Cyclic L27-11 is an antibacterial peptide. L27-11 shows antimicrobial activity in the nanomolar range against Pseudomonas aeruginosa. Alternative Names: Thr-Trp-Leu-Lys-Lys-Arg-Arg-Trp-Lys-Lys-Ala-Lys. Grades: 97.5%. Molecular formula: C87H143N27O16. Mole weight: 1823.26. | |
| Cyclic somatostatin diacetate | Cyclic somatostatin diacetate is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. It's an experimental diabetes drug. Alternative Names: Somatostatin (sheep), diacetate (salt); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.2CH3CO2H (Disulfide bridge: Cys3-Cys14); L-alanyl-glycyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine (3->14)-disulfide diacetic acid; Somatostatin diacetate. Grades: ≥95%. CAS No. 73977-20-5. Molecular formula: C76H104N18O19S2.2C2H4O2. Mole weight: 1757.99. | |
| Cyclin-A1 (271-279) | Cyclin-A1 (271-279) is amino acids 271 to 279 fragment of Cyclin-A1. Cyclin-A1 primarily functions in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. | |
| Cyclin-A1 (385-395) | Cyclin-A1 (385-395) is amino acids 385 to 395 fragment of Cyclin-A1. Cyclin-A1 primarily functions in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. | |
| Cyclin-dependent kinase 4 (924-932) | Cyclin-dependent kinase 4 (924-932) is a truncated fragment of Cyclin-dependent kinase 4. This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Alternative Names: cell division protein kinase 4 (924-932). | |
| Cyclo(-Arg-Ala-Asp-D-Phe-Cys) | Cyclo(-Arg-Ala-Asp-D-Phe-Cys) is a control peptide for the αvβ3 integrin binding cyclic RGD peptide c(RGDfC). Alternative Names: c(RADfC); Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl-L-arginyl). Grades: ≥95%. CAS No. 1055991-02-0. Molecular formula: C25H36N8O7S. Mole weight: 592.68. | |
| Cyclo(-Arg-Ala-Asp-D-Tyr-Lys) | Cyclo(-Arg-Ala-Asp-D-Tyr-Lys) is a control peptide for c(RGDyK). Alternative Names: c(RADyK); cyclo[L-alanyl-L-alpha-aspartyl-D-tyrosyl-L-lysyl-L-arginyl]; Cyclo(L-alanyl-L-α-aspartyl-D-tyrosyl-L-lysyl-L-arginyl). Grades: ≥95%. CAS No. 1193347-53-3. Molecular formula: C28H43N9O8. Mole weight: 633.71. | |
| Cyclo(-Arg-Gly-Asp-D-Phe-Glu) | Cyclo(-Arg-Gly-Asp-D-Phe-Glu), a cyclic RGD peptide, has been used as an integrin ligand for radiologic labeling, on gold nanoparticles and for the delivery of nanomedicine. Its negative control c(RADfE) is also available. Alternative Names: cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl]; c(RGDfE); Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-α-glutamyl). Grades: ≥95%. CAS No. 756500-22-8. Molecular formula: C26H36N8O9. Mole weight: 604.62. | |
| Cyclo(-Arg-Gly-Asp-D-Phe-Val) | Cyclo(-Arg-Gly-Asp-D-Phe-Val) is a potent inhibitor of cell adhesion. It inhibited tumor cell adhesion to laminin and vitronectin substrates. Alternative Names: c-[-Arg-Gly-Asp-fV-]; Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-valyl). CAS No. 137813-35-5. Molecular formula: C26H38N8O7. Mole weight: 574.63. | |
| Cyclo(-Arg-Gly-Asp-D-Tyr-ε-azido-Nle) | Cyclo(-Arg-Gly-Asp-D-Tyr-ε-azido-Nle), an azido derivative of cRGDyK, can be modified or linked to carriers by click chemistry. Alternative Names: Azido-c(RGDyK); Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-6-azido-L-norleucyl); cyclo[Arg-Gly-Asp-D-Tyr-Nle(N3)]. Grades: ≥95%. CAS No. 1392269-21-4. Molecular formula: C27H39N11O8. Mole weight: 645.68. | |
| Cyclo(-Arg-Gly-Asp-D-Tyr-Lys(Tide FluorTM 7WS)) | Cyclo(-Arg-Gly-Asp-D-Tyr-Lys(Tide FluorTM 7WS)) is a cyclic RGD peptide labeled with a fluorophore absorbing at 749 nm and emitting at 775 nm. Alternative Names: c[RGDyK(Tide FluorTM 7WS)]. Grades: ≥90%. Molecular formula: C27H41N9O8 + dye. Mole weight: 1378. | |
| Cyclo(-D-Ala-D-Ala) | Cyclo(-D-Ala-D-Ala). Alternative Names: (3R,6R)-3,6-Dimethylpiperazine-2,5-Dione. Grades: ≥ 99% (Assay). CAS No. 23927-13-1. Molecular formula: C6H10N2O2. Mole weight: 142.16. | |
| Cyclo(-D-Ala-L-Pro) | Cyclo(-D-Ala-L-Pro). Alternative Names: (3R,8aS)-3-Methylhexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione; Cyclo(-D-Ala-Pro). Grades: ≥ 99% (HPLC). CAS No. 36238-64-9. Molecular formula: C8H12N2O2. Mole weight: 168.20. | |
| Cyclo(-D-His-Pro) | Cyclo(-D-His-Pro). Alternative Names: cyclo(D-histidyl-L-proline). CAS No. 75685-88-0. Molecular formula: C11H14N4O2. Mole weight: 234.25. | |
| Cyclo(-D-Leu-D-Pro) | Cyclo(-D-Leu-D-Pro). Alternative Names: cyclo(D)-Pro-(D)-Leu; (3R,8AR)-3-isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione. CAS No. 274680-11-4. Molecular formula: C11H18N2O2. Mole weight: 210.27. | |
| Cyclo(-D-Trp-Tyr) | Cyclo(-D-Trp-Tyr). Alternative Names: Cyclo(D-Trp-L-Tyr-); Trans-cyclo-(D-tryptophanyl-L-tyrosyl). CAS No. 852955-00-1. Molecular formula: C20H19N3O3. Mole weight: 349.38. | |
| Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide | Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis. Alternative Names: G 4120; G-4120; Cyclo-S-Ac-tyr-rgd-cys-OH (sulfoxide); L-Cysteine, N-(mercaptoacetyl)-D-tyrosyl-L-arginylglycyl-L-alpha-aspartyl-, cyclic (1-5)-disulfide, S-oxide. Grades: 95%. CAS No. 143120-27-8. Molecular formula: C26H36N8O11S. Mole weight: 668.68. | |
| Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro) | Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro), a cyclic RGD peptide, stimulates the contraction of rat afferent arterioles and is used for targeted delivery of cisplatin. It inhibits the adhesion of mouse B16 melanoma cells to fibronectin coated wells. Alternative Names: cyclo[L-arginyl-glycyl-L-alpha-aspartyl-L-seryl-L-prolyl-glycyl]; c(GRGDSP). Grades: ≥90%. CAS No. 135432-37-0. Molecular formula: C22H35N9O9. Mole weight: 569.58. | |
| Cyclo(-Gly-Arg-Gly-Glu-Ser-Pro) | Cyclo(-Gly-Arg-Gly-Glu-Ser-Pro) is the negative control for cGRGDSP. Alternative Names: c(GRGESP); Cyclo(L-arginylglycyl-L-α-glutamyl-L-seryl-L-prolylglycyl). Grades: ≥95%. CAS No. 2022956-43-8. Molecular formula: C23H37N9O9. Mole weight: 583.59. | |
| Cycloleucine | Cycloleucine is a competitive inhibitor of glycine modulatory site of N-methyl-D-aspartate (NMDA) receptor, with immunosuppressive, antineoplastic and cytostatic activities. It competitively inhibits methionine adenosyltransferase, thereby inhibiting S-adenosylmethionine (SAM) synthesis from methionine and ATP, and subsequent nucleic acid methylation and polyamine production. Alternative Names: 1-Aminocyclopentanecarboxylic acid; 1-Amino-1-cyclopentanecarboxylic acid; 1-Amino-1-carboxycyclopentane; NSC 1026; NSC 112194; NSC 112195; NSC 112197; ACPC. Grades: ≥98%. CAS No. 52-52-8. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| Cyclopeptide E | Cyclopeptide E is produced by Annona cherimola. It probably participates in a plant defense mechanism. Cyclopeptide E has cytotoxic activity against human nasopharyngeal carcinoma with an IC50 of 17 nM. | |
| Cyclopeptide F | Cyclopeptide F is produced by Annona cherimola. It probably participates in a plant defense mechanism. Cyclopeptide F has cytotoxic activity against human nasopharyngeal carcinoma with an IC50 of 60 nM. | |
| Cyclo(-Phe-Trp) | Cyclo(-Phe-Trp), a metabolite of Aspergillus, is a natural product found in Aspergillus flavus and Aspergillus sydowii. Alternative Names: (11S,14S)-Cyclo-(L-Trp-L-Phe); Cyclo(L-Trp-L-Phe); (3S,6S)-3-Benzyl-6-(indol-3-ylmethyl)-2,5-piperazinedione; Cyclo(L-phenylalanyl-L-tryptophanyl); 2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(phenylmethyl)-, (3S,6S)-. Grades: ≥95%. CAS No. 6521-48-8. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| Cyclopropaneboronic acid | Cyclopropylboronic Acid is an organoboronic acid commonly used in highly efficient Suzuki coupling reactions. Alternative Names: B-Cyclopropylboronic Acid; ACMC-1AMNO; Cyclopropyl Boronic Acid; Boronic Acid, Cyclopropyl- (9Ci); Cyclopropylboronic acid; cyclopropylboranediol; DTXSID00375402; QCR-242; ACN-S003927; 37410-EP2301922A1. Grades: > 98 % (GC). CAS No. 411235-57-9. Molecular formula: C3H7BO2. Mole weight: 85.9. | |
| Cyclopsychotride-A | Cyclopsychotride-A is isolated from Psychotria longipes. It probably participates in a plant defense mechanism. Cyclopsychotride-A has antibiotic activity. Cyclopsychotride-A inhibits the cytopathic effects and replication of the human immunodeficiency virus. It is active against both Gram-positive and Gram-negative bacteria. | |
| Cyclo(RADfK) | Cyclo(RADfK) is a selective α(V)β(3) integrin ligand. It has been used for research, therapy, and diagnosis of neoangiogenesis. It is also used as a negative control for the cyclo (-RGDfK-), the RGD peptide, which are modulators of cell adhesion and are recognized by several members of the integrin family. It has low affinity binding to integrin peptides. Uses: Cyclo(radfk) has been used for research, therapy, and diagnosis of neoangiogenesis. it is also used as a negative control for the cyclo (-rgdfk-), the rgd peptide. Alternative Names: c(RADfK); cyclo[L-alanyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl]. Grades: ≥95%. CAS No. 756500-23-9. Molecular formula: C28H43N9O7. Mole weight: 617.70. | |
| cyclo[RGD(DMNPB)fK] | cyclo[RGD(DMNPB)fK], a photosensitive caged RGD peptide, is used for efficient phototriggering of cell attachment. Alternative Names: Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl), 2-(4,5-dimethoxy-2-nitrophenyl)-1-methylpropyl ester. CAS No. 1035105-00-0. Molecular formula: C39H56N10O11. Mole weight: 840.94. | |
| cyclo(RGDfC) | Cyclo(-RGDfC) is a potent and selective inhibitor of the αvβ3 integrin receptor. Alternative Names: Cyclo(l-arginylglycyl-l-alpha-aspartyl-d-phenylalanyl-l-cysteinyl). Grades: ≥95%. CAS No. 862772-11-0. Molecular formula: C24H34N8O7S. Mole weight: 578.64. | |
| Cyclo(RGDfC) acetate | Cyclo(RGDfC) acetate is a potent and selective inhibitor of the αvβ3 integrin receptor. Alternative Names: Cyclo(-RGDfC) acetate; cyclo[Arg-Gly-Asp-D-Phe-Cys] acetate; cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-L-cysteinyl] acetic acid; Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl) acetate. Grades: ≥95%. CAS No. 2171504-31-5. Molecular formula: C26H38N8O9S. Mole weight: 638.69. | |
| cyclo(RGDyC) acetate | Cyclo(RGDyC) acetate, a cyclic RGDyc sequence, is an integrin avb3-affine polypeptide. Alternative Names: Cyclo(-RGDyC) acetate; cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-tyrosyl-L-cysteinyl] acetate; Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-cysteinyl) acetate. Grades: ≥95%. Molecular formula: C26H38N8O10S. Mole weight: 654.70. | |
| Cyclo(RGDyK) | Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt is a potent and selective αVβ3 integrin inhibitor. Grades: >98%. CAS No. 217099-14-4. Molecular formula: C27H41N9O8. Mole weight: 619.67. | |
| Cyclo(RGDyK)-Cy5.5 | Cyclo(RGDyK)-Cy5.5. Alternative Names: Cyclo(Arg-Gly-Asp-D-Tyr-Lys)-Cy5.5; c(RGDyK)-Cy5.5; Cyclo[L-arginylglycyl-L-α-aspartyl-D-tyrosyl-N6-[6-[2-[5-(3-ethyl-1,3-dihydro-1,1-dimethyl-6,8-disulfo-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-1,1-dimethyl-6,8-disulfo-1H-benz[e]indolio]-1-oxohexyl]-L-lysyl], inner salt; RGD-Cy 5.5. CAS No. 820967-21-3. Molecular formula: C68H83N11O21S4. Mole weight: 1518.71. | |
| Cyclo(RGDyK) Trifluoroacetate | Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. Alternative Names: Cyclo (RGDyK); Cyclo RGDyK; Cyclo(RGDyK) trifluoroacetate. Grades: >98%. CAS No. 250612-42-1. Molecular formula: C31H43F6N9O12. Mole weight: 847.71. | |
| Cycloserine Impurity 1 | D-Serine is a proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. It is a inhibitor of serine palmitoyltransferase. It is also a neuromodulator. Alternative Names: D-Serine; (R)-2-Amino-3-hydroxypropanoic Acid; (R)-2-Amino-3-hydroxypropanoic Acid; (R)-Serine; NSC 77689. Grades: ≥ 99% (Titration: anhydrous basis). CAS No. 312-84-5. Molecular formula: C3H7NO3. Mole weight: 105.09. | |
| Cycloserine Impurity 2 | Cycloserine Impurity 2 is a derivative of Cycloserine, renowned for its remarkable efficacy in treating tuberculosand sundry bacterial afflictions. Alternative Names: D-Serine Methyl Ester Hydrochloride; (R)-2-Amino-3-hydroxypropionic Acid Methyl Ester Hydrochloride; (R)-Methyl 2-Amino-3-hydroxypropanoate Hydrochloride; Methyl D-Serinate Hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 5874-57-7. Molecular formula: C4H10ClNO3. Mole weight: 155.58. | |
| Cyclosomatostatin | Cyclosomatostatin is a non-selective somatostatin (sst) receptor antagonist. It blocks the effects of CRF-induced suppression of gastric empyting and sst on airway β-adrenergic function. It also prevents growth hormone, insulin, glucagon release and modulation of ACh release. It acts as a sst receptor agonist in human neuroblastoma cell line SH-SY5Y. Uses: Hormone antagonists. Alternative Names: Cyclo(7-aminoheptanonyl-Phe-D-Trp-Lys-Thr[Bzl]); Cyclo[7-aminoheptanoyl-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-threonyl]. CAS No. 84211-54-1. Molecular formula: C44H57N7O6. Mole weight: 779.98. | |
| Cyclosomatostatin acetate | Cyclosomatostatin acetate is an effective antagonist of the somatostatin receptor. Cyclosomatostatin acetate inhibits SSTR1 signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer cells. Alternative Names: 1,4,7,10,13-Pentaazacycloeicosane-2,5,8,11,14-pentone, 6-(4-aminobutyl)-9-(1H-indol-3-ylmethyl)-3-[(1R)-1-(phenylmethoxy)ethyl]-12-(phenylmethyl)-, acetate (1:1), (3S,6S,9R,12S)-; Cyclo[7-aminoheptanoyl-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-threonyl], monoacetate; Cyclo-Somatostatin acetate. Grades: ≥95%. CAS No. 211056-95-0. Molecular formula: C44H57N7O6.C2H4O2. Mole weight: 840.02. | |
| Cyclosporin A-Derivative 1 | Cyclosporin A-Derivative 1 is a metabolite of cyclosporine A. Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin phosphatase. Alternative Names: Leu-Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu-Sar.BF4; (7S,10S,13S,16S,19S,22R,25S,28S,31S,34S)-10-[(1R,2R,4E)-1-Acetoxy-2-methyl-4-hexen-1-yl]-7-ethyl-16,19,28-triisobutyl-13,31-diisopropyl-N,5,11,14,17,20,22,25,29,36-decamethyl-3,6,9,12,15,18,21,24,27,3 0,33-undecaoxo-2-oxa-5,8,11,14,17,20,23,26,29,32-decaazaheptatriacontan-34-aminium tetrafluoroborate. Grades: ≥98%. CAS No. 1487360-85-9. Molecular formula: C65H118BF4N11O14. Mole weight: 1364.50. | |
| Cyclosporin A-Derivative 1 Free base | Cyclosporin A-Derivative 1 Free base is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: Cyclosporin A open ring; N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Cyclosporin A-Derivative 1 (Free base); Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar}; LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar}. Grades: ≥95%. CAS No. 286852-20-8. Molecular formula: C65H117N11O14. Mole weight: 1276.69. | |
| Cyclosporin A-Derivative 2 | Cyclosporin A-Derivative 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: L-Valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Des(N-Methyl-leucyl) Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Glycine, L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester. Grades: ≥95%. CAS No. 156047-45-9. Molecular formula: C58H104N10O13. Mole weight: 1149.51. | |
| Cyclotide C, partial | Cyclotide C, partial is isolated from Viola odorata. It has antimicrobial activity. | |
| Cyclotide vibi-E | Cyclotide vibi-E is produced by Viola biflora. It probably participates in a plant defense mechanism. Cyclotide vibi-E has cytotoxic activity, active against a human lymphoma cell line with an IC50 of 3.2 μM. | |
| Cyclotide vibi-H | Cyclotide vibi-H is produced by Viola biflora. It has antimicrobial and anticancer activity. | |
| Cyclotraxin B | Cyclotraxin B is a selective and potent Trk B (BDNF/NT-3) receptor inhibitor with an IC50 value of 0.30 nM. It prevents receptor activation by BDNF without interfering with BDNF binding. It sometimes fused with tat-protein for increased brain permeability in rodent studies. It has been shown to exhibit putative anxiolytic properties in mice. It prevents cold allodynia induced by BDNF in mice and reduces cocaine self-administration. Alternative Names: L-Cysteinyl-L-asparaginyl-L-prolyl-L-methionylglycyl-L-tyrosyl-L-threonyl-L-lysyl-L-a-glutamylglycyl-L-cysteine, cyclic (1>11)-disulfide. Grades: >98%. CAS No. 1203586-72-4. Molecular formula: C48H73N13O17S3. Mole weight: 1200.36. | |
| Cycloviolacin H2 | Cycloviolacin H2 is produced by Viola hederacea. It probably participates in a plant defense mechanism. | |
| Cycloviolacin H3 | Cycloviolacin H3 is produced by Viola hederacea. It probably participates in a plant defense mechanism. | |
| Cycloviolacin H4 | Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. Cycloviolacin H4 exhibits the most potent hemolytic activity in cyclotides reported so far, and this activity correlates with the size of a surface-exposed hydrophobic patch. Alternative Names: cycloviolacin H4; CHEMBL499782. Molecular formula: C132H200N34O41S6. Mole weight: 3111.6. | |
| Cycloviolacin O1 | Cycloviolacin O1 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O13 | Cycloviolacin O13 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O13 has hemolytic activity. Molecular formula: C133H207N37O38S6. Mole weight: 3124.67. | |
| Cycloviolacin O14 | Cycloviolacin O14 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O14 has hemolytic activity. Molecular formula: C132H197N35O41S6. Mole weight: 3122.57. | |
| Cycloviolacin O15 | Cycloviolacin O15 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O15 has hemolytic activity. Molecular formula: C130H195N33O39S6. Mole weight: 3036.52. | |
| Cycloviolacin O16 | Cycloviolacin O16 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O17 | Cycloviolacin O17 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O18 | Cycloviolacin O18 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O19 | Cycloviolacin O19 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin-O2 | Cycloviolacin-O2 is isolated from Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin-O2 has strong cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines, and against primary chronic lymphocytic leukemia and ovarian carcinoma cells. It also has weaker cytotoxic activity against normal lymphocytes and hemolytic activity. Alternative Names: Cycloviolacin-O2; IHB9R8ET7W; CHEMBL4210529; cycloviolacin O2; 261714-23-2; Cyclo(Gly-Ile-Pro-Cys-Gly-Glu-Ser-Cys-Val-Trp-Ile-Pro-Cys-Ile-Ser-Ser-Ala-Ile-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Arg-Asn) 4->18,6->22, 11->27 trisdisulfide; UNII-IHB9R8ET7W; CHEMBL4285275; BDBM50452159. CAS No. 261714-23-2. Molecular formula: C133H207N37O39S6. Mole weight: 3140.7. | |
| Cycloviolacin O20 | Cycloviolacin O20 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O21 | Cycloviolacin O21 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O22 | Cycloviolacin O22 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O23 | Cycloviolacin O23 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
| Cycloviolacin O24 | Cycloviolacin O24 is produced by Viola odorata. It probably participates in a plant defense mechanism. Molecular formula: C126H179N35O42S6. Mole weight: 3048.36. | |
| Cycloviolacin O25 | Cycloviolacin O25 is produced by Viola odorata. It probably participates in a plant defense mechanism. | |
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