BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a LRH-1 agonist and the dilauroyl diester of phosphatidylcholine, one of the most common cell membrane lipids. Alternative Names: Dilauroyl phosphatidylcholine; 1,2-Didodecanoyl-sn-glycero-3-phosphocholine; 1,2-Dilauroyl-sn-glycero-3-PC; L-α-Dilauroyl Phosphatidylcholine; L-α-Dilauroylglyceryl-3-phosphorylcholine. Grades: ≥98%. CAS No. 18194-25-7. Molecular formula: C32H64NO8P. Mole weight: 621.83.
DL-Phenylalanine 4-nitroanilide hydrochloride salt
DL-Phenylalanine 4-nitroanilide is a chromogenic substrate. Alternative Names: DL-Phe-pNA HCl; (2R)-2-amino-N-(4-nitrophenyl)-3-phenylpropanamide hydrochloride. Grades: ≥ 99% (HPLC). CAS No. 14235-18-8. Molecular formula: C15H15N3O3·HCl. Mole weight: 321.80.
DL-Proline methyl ester hydrochloride (CAS# 79397-50-5 ) is a useful research chemical. Alternative Names: 1-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)propan-2-one; 1-(4-bromo-3,5-dimethylpyrazolyl)acetone; Methyl pyrrolidine-2-carboxylate hydrochloride. Grades: 95 %. CAS No. 79397-50-5. Molecular formula: C6H12ClNO2. Mole weight: 165.62.
DL-Pyroglutamic acid
Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue. Alternative Names: DL-Pyroglutamic acid;149-87-1;5-Oxopyrrolidine-2-carboxylic acid;2-Pyrrolidone-5-carboxylic acid;5-Oxo-DL-proline;5-OXOPROLINE;DL-Proline, 5-oxo-;DL-2-Pyrrolidone-5-carboxylic acid;DL-Glutamic Acid Lactam;dl-pyrrolidonecarboxylic acid;6VT1YZM21H;CHEBI:16010;D-(+)-Pyroglutamic Acid;MFCD00064322;NSC-40887;OXOPROLINE;DL-Pidolic acid;5-Oxo-L-proline-d5;UNII-6VT1YZM21H;DL-5-Oxoproline;5-Oxoproline #;DL. Grades: ? 95%. CAS No. 149-87-1. Molecular formula: C5H7NO3. Mole weight: 129.11.
DL-Threo-3-Phenylserine. Alternative Names: H-DL-Phe(b-OH)-OH; beta-Hydroxyphenylalanine. CAS No. 7695-56-9. Molecular formula: C9H11NO3. Mole weight: 181.19.
DL-threo-Droxidopa
A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian. Uses: A synthetic amino acid precursor of norepinephrine. antiparkinsonian. Alternative Names: (βS)-rel-β,3-Dihydroxy-D-tyrosine; DL-threo-3-(3,4-Dihydroxyphenyl)serine; DL-DOPS; L-Threodops; DL-threo-3,4-Dihydroxyphenylserine; DL-threo-DOPS; threo-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic Acid; threo-β-(3,4-dihydroxyphenyl)-DL-serine. Grades: 95%. CAS No. 3916-18-5. Molecular formula: C9H11NO5. Mole weight: 213.19.
DL-Thyronine
DL-Thyronine. Alternative Names: 3-[p-(p-Hydroxyphenoxy)phenyl]-DL-alanine. Grades: ≥ 98% (TLC). CAS No. 1034-10-2. Molecular formula: C15H15NO4. Mole weight: 273.28.
DL-tryptophan amide hydrochloride
DL-tryptophan amide hydrochloride. Uses: An amino acid amide used as a substrate for studying the action of aminopeptidase enzyme. note: the isomer l-tryptophanamide, hydrochloride is also available as catalogue number t895505. Alternative Names: DL-Trp-NH2 HCl; 2-amino-3-(1H-indol-3-yl)propanamide hydrochloride. Grades: ≥ 99% (TLC). CAS No. 67607-61-8. Molecular formula: C11H13N3O·HCl. Mole weight: 239.70.
D-Lys(Cbz)-NCA is widely used as a precursor for the synthesis of polypeptides. Alternative Names: N6-Carbobenzoxy-D-lysine-N-Carboxyanhydride; N-ε-Benzyloxycarbonyl-D-lysine Carboxyanhydride. CAS No. 68199-92-8. Molecular formula: C15H18N2O5. Mole weight: 306.31.
D-Lysinamide dihydrochloride
D-Lysinamide dihydrochloride. Alternative Names: H-D-Lys-NH2 2HCl. Grades: 95%. CAS No. 205598-51-2. Molecular formula: C6H17Cl2N3O. Mole weight: 218.13.
D-Lys(tfa)-NCA
Applications: N-[4-[(4R)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide is used in the preparation of phosphate-binding particles which are used to reduce the phosphate level in patients with chronic kidney diseases. Alternative Names: Acetamide, N-[4-[(4R)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-; (R)-N-(4-(2,5-Dioxooxazolidin-4-yl)butyl)-2,2,2-trifluoroacetamide. CAS No. 1809273-81-1. Molecular formula: C9H11F3N2O4. Mole weight: 268.19.
D-Lys(Z)-Pro-Arg-pNA
D-Lys(Z)-Pro-Arg-pNA is a luminescent substrate of activated protein C (APC). Alternative Names: Chromozym Pca; (5(R)-Amino-6-{2(S)-[4-guanidino-1-(4-nitro-phenylcarbamoyl)-butylcarbamoyl]-pyrrolidin-1(S)-yl}-6-oxo-hexyl)-carbamic acid benzyl ester; L-Argininamide, N6-[(phenylmethoxy)carbonyl]-D-lysyl-L-prolyl-N-(4-nitrophenyl)-; d-Lys(Z)-PR-pNA. Grades: ≥95%. CAS No. 108963-69-5. Molecular formula: C31H43N9O7. Mole weight: 653.73.
D-Lys(Z)-Pro-Arg-pNA diacetate
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic substrate. Alternative Names: Spectrozyme PCa; Chromozym Pca diacetate; H-D-Lys(Cbz)-Pro-Arg-pNA.diacetate; d-Lys(Z)-P-R-pNA.diacetate; N6-[(Benzyloxy)carbonyl]-D-lysyl-L-prolyl-N-(4-nitrophenyl)argininamide acetate (1:2). Grades: ≥95%. CAS No. 108963-70-8. Molecular formula: C31H43N9O7.2C2H4O2. Mole weight: 773.83.
Dm-AMP1
DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckII), interacts with sphingolipids from Saccharomyces cerevisiae.
D-meta-Tyrosine
D-meta-Tyrosine. Alternative Names: D-meta-TyrosineD-3-Hydroxy-phenylalanine. Grades: ≥ 98% (HPLC). CAS No. 32140-49-1. Molecular formula: C9H11NO3. Mole weight: 181.19.
D-Methioninol. Alternative Names: (R)-2-Amino-4-methylthio-1-butanol; D-Met-ol. Grades: ≥ 98% (TLC). CAS No. 87206-44-8. Molecular formula: C5H13NOS. Mole weight: 135.21.
DMPE
DMPE (1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine) is a high purity phospholipid utilized for liposome production. Alternative Names: 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine. Grades: ≥98%. CAS No. 998-07-2. Molecular formula: C33H66NO8P. Mole weight: 635.85.
DNA-binding protein RFX6 (414-431)
DNA-binding protein RFX6 (414-431) is a truncated fragment of DNA-binding protein RFX6. DNA-binding protein RFX6 is a transcription factor required to direct islet cell differentiation during endocrine pancreas development. Alternative Names: Regulatory factor X 6 (414-431); Regulatory factor X domain-containing protein 1 (414-431).
DNA-dependent protein kinase catalytic subunit (2836-2844)
DNA-dependent protein kinase catalytic subunit (2836-2844) is a peptide derived from DNA-dependent protein kinase catalytic subunit. PRKDC (DNA-PKcs) mutations were found in 3 out of 10 of endometriosis-associated ovarian cancers, as well as in the field defects from which they arose. They were also found in 10% of breast and pancreatic cancers. Alternative Names: DNA-PK catalytic subunit (2836-2844); DNA-PKcs (2836-2844).
DNA ligase 3 isoform alpha precursor (790-806)
DNA ligase 3 isoform alpha precursor (790-806) is a bioactive peptide of DNA ligase 3 isoform alpha precursor. DNA ligases are critical enzymes of DNA metabolism. DNA ligase 3 isoform alpha is involved in repair and recombination.
D-NAME hydrochloride
N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME). D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Alternative Names: D-NG-Nitroarginine methyl ester; N(G)-Nitro-D-Arginine methyl ester; D-NAME, NG-Nitro-D-arginine methyl ester hydrochloride. Grades: ≥95%. CAS No. 50912-92-0. Molecular formula: C7H15N5O4·HCl. Mole weight: 269.7.
DNA repair protein RAD50 (1281-1289)
A fragment of DNA repair protein RAD50. RAD50 is a component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. This peptide can be used in Ovarian carcinoma research.
D-Nipecotic acid
D-Nipecotic acid. Alternative Names: H-D-Pic(3)-OH; H-D-Nipc-OH; (R)-Piperidine-3-carboxylic acid. Grades: ≥ 98% (assay by titration). CAS No. 25137-00-2. Molecular formula: C6H11NO2. Mole weight: 129.16.
D-Norvaline
D-Norvaline. Alternative Names: D(-)-Norvaline; H-D-Nva-OH. Grades: ≥ 99% (Assay). CAS No. 2013-12-9. Molecular formula: C5H11NO2. Mole weight: 117.2.
D-Norvalinol (CAS# 80696-30-6) is a useful research chemical compound. Alternative Names: H-D-Nva-ol; (R)-2-Amino-1-pentanol; (R)-2-Aminopentan-1-ol; (R)-(-)-2-Amino-1-pentanol; (2R)-2-aminopentan-1-ol. Grades: ≥ 98 %. CAS No. 80696-30-6. Molecular formula: C5H13NO. Mole weight: 103.17.
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. It is cleaved to release the fluorescent moiety N-methylanthranilic acid (Nma), of which the fluorescence can be used to quantify MMP-1 and MMP-9 activity. Alternative Names: Matrix Metalloproteinase-1 / Matrix Metalloproteinase-9 Fluorogenic Substrate; MMP-1/MMP-9 Fluorogenic Substrate; 1-(2,4-dinitrophenyl)-L-prolyl-3-cyclohexyl-L-alanylglycyl-S-methyl-L-cysteinyl-L-histidyl-L-alanyl-N6-[2-(methylamino)benzoyl]-L-lysinamide. Grades: ≥95%. CAS No. 150956-92-6. Molecular formula: C49H68N14O12S. Mole weight: 1077.23.
Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2
Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2, a peptide utilized for biological research, is an exemplary agent for evaluating proteolytic activity and inhibitor effects. Notably, its potential in disease treatment, encompassing cancer and inflammation, has put it at the forefront of therapeutic development. In addition to its promising therapeutic properties, Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 may serve as a vital diagnostic tool for identifying pertinent enzymes within biological samples, providing otherwise unattainable insights for investigative purposes. Alternative Names: N-(2,4-DINITROPHENYL)-PRO-LEU-GLY-LEU-TRP-ALA-D-ARG AMIDE; MMP SUBSTRATE, FLUOROGENIC; 360 MMP FRET SUBSTRATE I; DNP-PRO-LEU-GLY-LEU-TRP-ALA-D-ARG-NH2; DNP-PLGLWAR-NH2; N-(2,4-dinitrophenyl)-pro-leu-gly-leu-*trp-ala-D-. Grades: 98%. CAS No. 121282-17-5. Molecular formula: C45H64N14O11. Mole weight: 977.08.
D-Nva-Ome HCl
D-Nva-Ome HCl. Alternative Names: D-Norvaline, methyl ester; (R)-Methyl 2-aminopentanoate; methyl D-norvalinate. CAS No. 21685-17-6. Molecular formula: C6H13NO2. Mole weight: 131.17.
DO3A tert-Butyl ester
DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Alternative Names: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate; DO3A-t-Bu-ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester. Grades: >98%. CAS No. 122555-91-3. Molecular formula: C26H50N4O6. Mole weight: 514.70.
Docetaxel Related Compound 1 ((2R, 3S)-3-Phenylisoserine)
Intermediate for the synthesis of taxol. Alternative Names: (2R,3S)-3-Amino-2-hydroxy-3-phenyl-propanoic acid. Grades: ≥ 98% (NMR). CAS No. 136561-53-0. Molecular formula: C9H11NO3. Mole weight: 181.19.
Dolabellanin-B2
Dolabellanin-B2 has antibacterial activity against Gram-negative bacteria E.coli JM109 and DH5-alpha, H.influenza IID 983, and V.vulnificus RIMD 2219009. Dolabellanin-B2 has antibacterial activity against Gram-positive bacteria S.aureus IID 1677, B.subtilis RIMD 0225014 and L.monocytogenes VIU206. It also possesses antifungal activity against S.cerevisiae A581A, S.pombe IFO 1628, C.albicans and TIMM-1623, and C.tropicalis TIMM-0313.
Dolastatin 10
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibiting microtubule assembly. Uses: Adcs cytotoxin. Alternative Names: DLS 10; NSC 376128; Dolastatin-10; DLS-10; DLS10; NSC376128; NSC-376128; L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-,[2S-[1[1R*(R*),2S*],2R*[1S*,2S*,3(R*)]]]-. Grades: >98%. CAS No. 110417-88-4. Molecular formula: C42H68N6O6S. Mole weight: 785.09.
Dominulin-A
Dominulin A has antibacterial activity. The source of Dominulin A is the social paper wasp, Polistes dominulus. Grades: >97% by HPLC.
Dominulin-B
Dominulin-B shows antimicrobial activity against the Gram-positive bacteria B.subtilis, and the Gram-negative bacteria E.coli JM109 (MIC=8 μg/ml).
DOPG
DOPG is a phosphatidylglycerol in which the phosphatidyl acyl groups are both oleoyl. It has been used to physically stabilize emulsions and suspensions. It is also used in formulations of pulmonary surfactants, intravenous fat emulsions, and oral solutions. Alternative Names: Dioleoyl phosphatidylglycerol; 1,2-Dioctadecenoyl-sn-glycero-3-[phospho-rac-(1-glycerol)]; C18:1 phosphatidylglycerol; C18:1 PG; DOPG; 3-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propyl (9Z)-octadec-9-enoate. Grades: ≥95% by HPLC. CAS No. 62700-69-0. Molecular formula: C42H79O10P. Mole weight: 775.04.
DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Alternative Names: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61.