BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Valine amide hydrochloride | D-Valine amide hydrochloride. Alternative Names: D-Val-NH2 HCl; (R)-2-Amino-3-methylbutanamide hydrochloride. Grades: ≥ 98% (assay). CAS No. 133170-58-8. Molecular formula: C5H12N2O·HCl. Mole weight: 152.60. |  |
| D-Valine benzyl ester 4-toluenesulfonate salt | D-Valine benzyl ester 4-toluenesulfonate salt. Alternative Names: D-Val-OBzl TosOH; (R)-Benzyl 2-amino-3-methylbutanoate 4-methylbenzenesulfonate. Grades: ≥ 98% (HPLC). CAS No. 17662-84-9. Molecular formula: C12H17NO2·C7H8O3S. Mole weight: 379.50. | |
| D-Valine ethyl ester hydrochloride | D-Valine ethyl ester hydrochloride. Alternative Names: D-Val-OEt HCl; Ethyl D-valinate hydrochloride; (R)-Ethyl 2-amino-3-methylbutanoate hydrochloride. Grades: ≥ 99% (HPLC). CAS No. 73913-64-1. Molecular formula: C7H15NO2·HCl. Mole weight: 181.65. | |
| D-Valine methyl ester hydrochloride | D-Valine methyl ester hydrochloride. Alternative Names: D-Val-OMe HCl; Methyl D-valinate hydrochloride. Grades: ≥ 99% (Assay). CAS No. 7146-15-8. Molecular formula: C6H13NO2·HCl. Mole weight: 167.60. | |
| D-Valine tert-butyl ester hydrochloride | D-Valine tert-butyl ester hydrochloride. Alternative Names: D-Val-OtBu HCl; (R)-tert-butyl 2-amino-3-methylbutanoate hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 104944-18-5. Molecular formula: C9H19NO2·HCl. Mole weight: 209.70. | |
| D-Valinol | D-Valinol (CAS# 4276-09-9) is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease. Alternative Names: H-D-Val-ol; (R)-(-)-2-Amino-3-methyl-1-butanol. Grades: ≥ 99 % (GC). CAS No. 4276-9-9. Molecular formula: C5H13NO. Mole weight: 103.2. | |
| D-Val-Leu-Lys 4-nitroanilide dihydrochloride | D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Alternative Names: (S)-6-Amino-2-((S)-2-((R)-2-amino-3-methylbutanamido)-4-methylpentanamido)-N-(4-nitrophenyl)hexanamide dihydrochloride; H-D-Val-Leu-Lys-pNA 2HCl. CAS No. 62354-43-2. Molecular formula: C23H40Cl2N6O5. Mole weight: 551.5. | |
| D-Vinylglycine | D-Vinylglycine. Alternative Names: 3-Butenoic Acid, 2-Amino-, (2R)-. CAS No. 52795-52-5. Molecular formula: C4H7NO2. Mole weight: 101.1. | |
| DX600 | DX600 is an inhibitor of angiotensin-converting enzyme 2 (ACE2). Alternative Names: DX-600; Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2 (Disulfide bridge: Cys6-Cys17); N-{[(6S,9R,14R,17S,20S,23S,25aS,31S,34S,37S,40S,42aS)-9-[(N-Acetylglycyl-L-α-aspartyl-L-tyrosyl-L-seryl-L-histidyl)amino]-17-(4-aminobutyl)-37-(3-carbamimidamidopropyl)-31,34-bis(4-hydroxybenzyl)-6-(hydroxymethyl)-20,23-bis(1H-indol-3-ylmethyl)-40-isobutyl-5,8,16,19,22,25,30,33,36,39,42-undecaoxooctatriacontahydro-1H,13H-dipyrrolo[2,1-p:2',1'-e1][1,2,5,8,11,14,17,20,23,26,29,32,35]dithiaundecaazacyclooctatriacontin-14-yl]carbonyl}-L-threonyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-α-glutamylglycylglycylglycinamide; N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide. Grades: ≥95%. CAS No. 478188-26-0. Molecular formula: C141H185N35O40S2. Mole weight: 3074.32. | |
| DX600 TFA | DX600 TFA is an inhibitor of angiotensin-converting enzyme 2 (ACE2) and does not cross-react with ACE. Alternative Names: Glycinamide, N-acetylglycyl-L-α-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-α-glutamylglycylglycyl-, cyclic (6→17)-disulfide, trifluoroacetate salt (1:1); Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2.TFA (Disulfide bridge: Cys6-Cys17); N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide trifluoroacetic acid. Grades: ≥95%. Molecular formula: C123H169F3N32O39S2. Mole weight: 2841.01. | |
| Dybowskin-1CDYa | Dybowskin-1CDYa is an antimicrobial peptide produced by Rana dybowskii. It has activity against the Gram-positive bacterium S.aureus (MIC=6 μM) and the Gram-negative bacterium E.coli (MIC=3 μM). Dybowskin-1CDYa lacks hemolytic activity against human erythrocytes. | |
| Dybowskin-2 | Dybowskin-2 has antibacterial and antifungal activity. The source of Dybowskin-2 is Rana dybowskii. Grades: >97% by HPLC. | |
| Dybowskin-2CDYa | Dybowskin-2CDYa is an antimicrobial peptide. It has activity against the Gram-positive bacterium S.aureus (MIC=6 μM) and the Gram-negative bacterium E.coli (MIC=3 μM). Dybowskin-2CDYa lacks hemolytic activity against human erythrocytes. Grades: >96% by HPLC. | |
| Dybowskin-2CDYb | Dybowskin-2CDYb is an antimicrobial peptide from Rana dybowskii. | |
| Dybowskin-3 | Dybowskin-3 is active against S. aureus, B. cereus, and S. lactis (MIC 37.5 uM), C. albicans (MIC 50 uM), and cancer cells MCF7 cells and Hela cells (IC50 50 uM). Alternative Names: Brevinin-2DYc. | |
| Dybowskin-4 | Dybowskin-4 has antibacterial and antifungal activity. Dybowskin-4 was found in Rana dybowskii. Grades: >96% by HPLC. | |
| Dybowskin-5 | Dybowskin-5 has antibacterial and antifungal activity. Dybowskin-4 was found in Rana dybowskii. Grades: >96% by HPLC. | |
| Dybowskin-6 | Dybowskin-6 has antibacterial and antifungal activity. Dybowskin-4 was found in Rana dybowskii. | |
| Dynamin inhibitory peptide, myristoylated | An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Alternative Names: AKOS024456771; Dynamin inhibitory peptide,myristoylated; PD079118; S-251634-22-7. Grades: >99%. CAS No. 251634-22-7. Molecular formula: C61H107N19O14. Mole weight: 1330.64. | |
| Dynorphin (1-17) | Dynorphin A is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Uses: Neurotransmitter agents. Alternative Names: Dynorphin A (swine); Dynorphin A (pig); 1-17-Dynorphin; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-; Dyn-A17; Dynorphin 17; Dynorphin A; Dynorphin A (1-17); Dynorphin A (human); Dynorphin A (porcine); Dynorphin A (rat); Dynorphin A 1-17; Dynorphin-A (Bos taurus); Porcine dynorphin (1-17); Porcine dynorphin A (1-17); Proteins, Dyn-A17; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln. Grades: ≥95%. CAS No. 80448-90-4. Molecular formula: C99H155N31O23. Mole weight: 2147.51. | |
| Dynorphin A 1-10 | Dynorphin A 1-10 is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with IC50 of 42.0 μM. Alternative Names: Dynorphin A, porcine, fragment 1-10; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline; Dynorphin A (1-10), porcine. Grades: ≥95%. CAS No. 79994-24-4. Molecular formula: C57H91N19O12. Mole weight: 1234.45. | |
| Dynorphin A 1-10 acetate | Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with an IC50 of 42.0 μM. Alternative Names: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline acetic acid; 1-10-Dynorphin A (swine) acetate; α-Neoendorphin (pig), 7-L-arginine-8-L-isoleucine-9-L-arginine-10-L-proline-, acetate (1:1); Porcine dynorphin A (1-10) acetate. Grades: ≥95%. Molecular formula: C59H95N19O14. Mole weight: 1294.53. | |
| Dynorphin A (1-10) TFA | Dynorphin A (1-10) TFA is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. Alternative Names: Dynorphin A (1-10) Trifluoroacetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.TFA; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline Trifluoroacetate; Dynorphin A (1-10), porcine Trifluoroacetate. Grades: >98%. Molecular formula: C57H91N19O12.C2HF3O2. Mole weight: 1348.48. | |
| Dynorphin A (1-13) amide | Dynorphin A (1-13) amide is an antagonist of human MC1, MC3 and MC4 receptors. Alternative Names: Dynorphin A (1-13), amide, porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide; Linear Dyn A-(1-13)NH2; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide. Grades: ≥95%. CAS No. 79515-34-7. Molecular formula: C75H127N25O14. Mole weight: 1602.97. | |
| Dynorphin A (1-8) | Dynorphin A (1-8) is an opioid octapeptide that exhibits agonist activity at μ and δ receptors. Alternative Names: Dynorphin A fragment 1-8 porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH. Grades: 98%. CAS No. 75790-53-3. Molecular formula: C46H72N14O10. Mole weight: 981.15. | |
| Dynorphin A (2-12), porcine | Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Alternative Names: Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu. Molecular formula: C60H105N21O12. Mole weight: 1312.69. | |
| Dynorphin A acetate | Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Alternative Names: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58. | |
| Dynorphin B 1-13 | Dynorphin B is a 13-residue opioid peptide, which is derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an opioid peptide and a κ-opioid receptor agonists. It has been implicated in antinociceptive functions. It has also been used to prime cardiogenesis in pluripotent embryonic stem cells. Alternative Names: Prodynorphin (226-238) (human); Prodynorphin (228-240) (porcine); Rimorphin; Dynorphin B 1-13; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-lysyl-L-valyl-L-valyl-L-threonine. Grades: ≥95%. CAS No. 83335-41-5. Molecular formula: C74H115N21O17. Mole weight: 1570.84. | |
| E07LKK | E07LKK has antibacterial activity against S. aureus, E.coli. | |
| E10KKL | E10KKL is a synthetic construct peptide. It has antibacterial activity. | |
| E12LLK | E12LLK is a synthetic construct peptide. It has antibacterial activity. | |
| E14KKL | E14KKL is a synthetic construct peptide. It has antibacterial activity. | |
| E14LKK / H14LKK | E14LKK / H14LKK is a synthetic construct peptide. It has antibacterial activity. | |
| E23GIG magainin 2 | E23GIG magainin 2 is a synthetic construct peptide. It has antibacterial activity. Grades: >98% by HPLC. | |
| E3 ligase Ligand-Linker Conjugates 30 | E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 can be used to design PROTAC MDM2 degrade. Alternative Names: 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; Pomalidomide-PEG3-C2-NH2; SCHEMBL19451340; BCP33441; HY-128716; CS-0099510; Cereblon Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 30. Grades: > 98%. CAS No. 2093416-31-8. Molecular formula: C21H28N4O7. Mole weight: 448.47. | |
| E3 ubiquitin-protein ligase Mdm2 (53-60) | E3 ubiquitin-protein ligase Mdm2 (53-60) is a peptide derived from E3 ubiquitin-protein ligase Mdm2. The E3 ubiquitin-protein ligase MDM2 is a novel interactor of the von Hippel-Lindau tumor suppressor. Alternative Names: Double minute 2 protein (53-60); RING-type E3 ubiquitin transferase Mdm2 (53-60); p53-binding protein Mdm2 (53-60). | |
| E3 ubiquitin-protein ligase RNF43 (11-19(20)) | A peptide fragment of E3 ubiquitin-protein ligase RNF43. E3 ubiquitin-protein ligase acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Alternative Names: RING finger protein 43 (11-19(20)); RING-type E3 ubiquitin transferase RNF43 (11-19(20)). | |
| E3 ubiquitin-protein ligase RNF43 (721-729) | A peptide fragment of E3 ubiquitin-protein ligase RNF43. E3 ubiquitin-protein ligase acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Alternative Names: RING finger protein 43 (721-729); RING-type E3 ubiquitin transferase RNF43 (721-729). | |
| E3 ubiquitin-protein ligase UBR4 (329-337) | E3 ubiquitin-protein ligase UBR4 (329-337) is a peptide derived from E3 ubiquitin-protein ligase UBR4. E3 ubiquitin-protein ligase is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Alternative Names: RING-type E3 ubiquitin transferase UBR4 (329-337); Retinoblastoma-associated factor of 600 kDa (329-337). | |
| E-76 | E-76, a potent anticoagulant, is an inhibitor of coagulation factor VIIa. It acts by binding to an exosite on the VIIa protease domain and non-competitively inhibits the activation of factor X and amide hydrolytic activity. Alternative Names: E-76; Acetyl-ALCDDPRVDRWYCQFVEG-amide; Ac-Ala-Leu-D-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH2 (Disulfide bridge: Cys3-Cys13); N-acetyl-L-alanyl-L-leucyl-D-cysteinyl-L-alpha-aspartyl-L-alpha-aspartyl-L-prolyl-L-arginyl-L-valyl-L-alpha-aspartyl-L-arginyl-L-tryptophyl-L-tyrosyl-L-cysteinyl-L-glutaminyl-L-phenylalanyl-L-valyl-L-alpha-glutamyl-glycinamide (3->13)-disulfide. Grades: ≥95% by HPLC. CAS No. 1926163-13-4. Molecular formula: C97H139N27O29S2. Mole weight: 2211.47. | |
| EA-CATH1 | EA-CATH1 has antibacterial activity. EA-CATH1 was found in Equus asinus. It appeared to be stable in serum and displayed no toxicity to human erythrocytes. Grades: >97% by HPLC. | |
| EAFP1 | EAFP1 is produced by Eucommia ulmoides. It has antifungal activity against P.infestans, A.lycopersici, V.dahliae, G.zeae, A.nicotianae, F.moniliforme, F.oxysporum and C.gossypii. Alternative Names: Antifungal peptide 1. | |
| EAFP2 | EAFP2 is produced by Eucommia ulmoides. The inhibition activity of EAFP2 can be effective on both chitin-containing and chitin-free fungi. Alternative Names: Antifungal peptide 2. | |
| EAK16-II | EAK16-II is a self-assembled peptide that can form a stable β-sheet structure and can be used as a carrier or matrix for cell culture. Alternative Names: Ac-Ala-Glu-Ala-Glu-Ala-Lys-Ala-Lys-Ala-Glu-Ala-Glu-Ala-Lys-Ala-Lys-NH2; L-Lysinamide, N-acetyl-L-alanyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-alanyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-alanyl-. Grades: ≥95%. CAS No. 157675-61-1. Molecular formula: C70H121N21O25. Mole weight: 1656.84. | |
| EAVRLFIEWLKNGGPSSGAPPPS | EAVRLFIEWLKNGGPSSGAPPPS is a polypeptide from patent CN 106029087 A. The incretin receptor ligands are derived from multiple skin toxicity Shan exosomes -3 skin of SDGTFTSDLSKQM Di EAVRLFIEWLKNGGPSSGAPPPS. Alternative Names: Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser. Grades: >98%. Molecular formula: C110H169N29O32. Mole weight: 2409.75. | |
| Ebecryl 3708 resin | Ebecryl 3708 resin is a modified bisphenol A epoxy bisacrylate with low viscosity and excellent curing reaction. Ebecryl 3708 resin films cured by ultraviolet light (UV) or electron beam (EB) show good flexibility, high gloss, toughness and excellent impact resistance. It can be used in clear coatings for paper, wood, flexible and rigid plastics, topcoats for wood and metal trim vehicles, adhesives for paper or film laminating, and lithography and screen ink vehicles. | |
| Ebenatide | Ebenatide is a long-acting glucagon-like peptide-1 recceptor agonist (GLP-1RA). Ebenatide is undergoing the clinical trial for the treatment of type 2 diabetes mellitus (T2DM). | |
| Ecallantide | Ecallantide is a drug used for the treatment of hereditary angioedema and in the prevention of blood loss in cardiothoracic surgery. Alternative Names: DX-88 cpd; EPI-KAL-2; Kalbitor. CAS No. 460738-38-9. Molecular formula: C305H442N88O91S8. Mole weight: 7053.83. | |
| EcAMP1 | EcAMP1 was shown to perform antifungal activity against several phytopathogenic fungi, with the most pronounced effect against members of the Fusarium genus. | |
| EcAMP3 | EcAMP3, a plant hairpin-like defense polypeptide isolated from the seeds of latent barnyard grass (Echinochloa crusgalli L.), has in vitro antifungal and antibacterial activities. Alternative Names: H-Gly-Ala-Asp-Arg-Cys-Arg-Glu-Arg-Cys-Glu-Arg-Arg-His-Arg-Gly-Asp-Trp-Gln-Gly-Lys-Gln-Arg-Cys-Leu-Met-Glu-Cys-Arg-Arg-Arg-Glu-Gln-Glu-Glu-Asp-OH (Disulfide bridge: Cys5-Cys27, Cys9-Cys23). Grades: ≥95%. CAS No. 2243219-65-8. Molecular formula: C172H282N72O57S5. Mole weight: 4430.91. | |
| EC-hepcidin3 | EC-hepcidin3, a new four-cysteine hepcidin isoform gene, was cloned from the marine-cultured orange-spotted grouper (Epinephelus coioides). | |
| Echistatin, α1 isoform | Echistatin, α1 isoform is a potent and irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). It exhibits inhibitory activity for bone reabsorption (IC50 = 0.1 nM) and prevents ADP-induced platelet aggregation by inhibiting glycoprotein IIb / IIIa (GpIIb / IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro. Alternative Names: H-Glu-Cys(1)-Glu-Ser-Gly-Pro-Cys(2)-Cys(3)-Arg-Asn-Cys(1)-Lys-Phe-Leu-Lys-Glu-Gly-Thr-Ile-Cys(4)-Lys-Arg-Ala-Arg-Gly-Asp-Asp-Met-Asp-Asp-Tyr-Cys(2)-Asn-Gly-Lys-Thr-Cys(3)-Asp-Cys(4)-Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr-OH; L-alpha-glutamyl-L-cysteinyl-L-alpha-glutamyl-L-seryl-glycyl-L-prolyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-asparagyl-L-cysteinyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-alpha-glutamyl-glycyl-L-threonyl-L-isoleucyl-L-cysteinyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-glycyl-L-alpha-aspartyl-L-alpha-aspartyl-L-methionyl-L-alpha-aspartyl-L-alpha-aspartyl-L-tyrosyl-L-cysteinyl-L-asparagyl-glycyl-L-lysyl-L-threonyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-L-asparagyl-L-prolyl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-alanyl-L-threonine (2->11),(7->32),(8->37),(20->39)-tetrakis(disulfide). Grades: >98%. CAS No. 154303-05-6. Molecular formula: C217H341N71O74S9. Mole weight: 5417.05. | |
| EcLTP | EcLTP has antibacterial and antifungal activity. EcLTP was found in Echinochloa crusgalli L. | |
| EC-proHep3 | EC-proHep3 has strong, rapid activity against Staphylococcus aureus and Pseudomonas stutzeri. It was found in Epinephelus coioides. | |
| EDDR1 (867-876) | EDDR1 (867-876) is a bioactive peptide of EDDR1. EDDR1, a membrane expressed protein associated with adhesion, has recently emerged as a new therapeutic target in several tumor types. Alternative Names: Epithelial Discoidin Domain Receptor 1 (867-876). | |
| Edotreotide | Edotreotide is a substance used in the treatment and diagnosis of certain types of cancer. Alternative Names: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; (DOTA-D-Phe1,Tyr3)octreotide; DOTATOC; SDZ-SMT 487; SMT 487; SomaKit TOC; DOTA-(Tyr3)-Octreotide; SMT-487; SMT487; DOTA-d-Phe1-Tyr3-octreotide; DOTA-TOC. Grades: 98%. CAS No. 204318-14-9. Molecular formula: C65H92N14O18S2. Mole weight: 1421.64. | |
| Ee-CBP | Ee-CBP is a hevein-type antimicrobial peptide from bark of the spindle tree (Euonymus europaeus L.). | |
| EEF2 (581-589) | EEF2 is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the ribosome. This protein is completely inactivated by EF-2 kinase phosphorylation. Alternative Names: Eukaryotic Translation Elongation Factor 2 (581-589); Polypeptidyl-TRNA Translocase (581-589). | |
| EELVDYKSCAHDWVY | EELVDYKSCAHDWVY. Alternative Names: Glu-Glu-Leu-Val-Asp-Tyr-Lys-Ser-Cys-Ala-His-Asp-Trp-Val-Tyr. Molecular formula: C84H117N19O27S. Mole weight: 1857.03. | |
| EETI Mutants (3-4A) | EETI Mutants (3-4A). Alternative Names: Pro-Thr-Ser-Cys-Ser-Gln-Asp-Ser-Asp-Cys-Leu-Ala-Gly-Cys-Val-Cys-Arg-Glu-Ala-Arg-Gly-Asp-Met-Pro-Arg-Thr-Cys-Gly-NH2 (Disulfide bond Cys2/Cys24, Cys14/Cys26, Cys20/Cys37). Molecular formula: C110H179N39O42S6. Mole weight: 2912.20. | |
| Eflornithine | Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Alternative Names: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grades: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
| Efpeglenatide | Efpeglenatide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA). Efpeglenatide has been developed as an injection for type 2 diabetes mellitus (T2DM). Alternative Names: efpeg. CAS No. 1296200-77-5. | |
| EFSLVVVRYPQYGVG | EFSLVVVRYPQYGVG. Alternative Names: Glu-Phe-Ser-Leu-Val-Val-Val-Arg-Tyr-Pro-Gln-Tyr-Gly-Val-Gly. Molecular formula: C81H121N19O22. Mole weight: 1712.97. | |
| EFTEVYEFDFKYDAPD-NH2 | EFTEVYEFDFKYDAPD-NH2. Alternative Names: H-Glu-Phe-Thr-Glu-Val-Tyr-Glu-Phe-Asp-Phe-Lys-Tyr-Asp-Ala-Pro-Asp-NH2. | |
| EFTUD2 (668-677) | EFTUD2 is required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Alternative Names: Elongation Factor Tu GTP Binding Domain Containing 2 (668-677); 116 KDa U5 Small Nuclear Ribonucleoprotein Component (668-677); Elongation Factor Tu GTP-Binding Domain-Containing Protein 2 (668-677). | |
| EGF-A Peptide | EGF-A Peptide. Alternative Names: Gly-Thr-Asn-Glu-Cys-Leu-Asp-Asn-Asn-Gly-Gly-Cys-Ser-His-Val-Cys-Asn-Asp-Leu-Lys-Ile-Gly-Tyr-Glu-Cys-Leu-Cys-Pro-Asp-Gly-Phe-Gln-Leu-Val-Ala-Gln-Arg-Arg-Cys-Glu-Asp-Ile-NH2 (Disulfide bond Cys5/Cys16, Cys12/Cys25, Cys27/Cys39). Molecular formula: C188H292N58O65S6. Mole weight: 4597.00. | |
| EGF-R (1138-1147) | A peptide fragment of EGF-R. Epidermal growth factor receptor (EGFR) is a prototypic cell-surface receptor belonging to the ErbB/HER onocogene family. Targeting of EGFR with specific blocking antibodies or inhibitors have been developing for treatment for EGFR-associated tumors. Alternative Names: Epidermal growth factor receptor (1138-1147). | |
| EGF Receptor (985-996) (human) | EGF Receptor (985-996) (human) exists on the cell surface and is activated by the binding of its specific ligands. EGFR belongs to the tyrosine kinase receptor (RTK) ErbB family. Alternative Names: L-Glutamine, L-α-aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-; L-Glutamine, N2-[1-[N-[N-[N-[N-[N-[N-[N-[N-(N-L-α-aspartyl-L-valyl)-L-valyl]-L-α-aspartyl]-L-alanyl]-L-α-aspartyl]-L-α-glutamyl]-L-tyrosyl]-L-leucyl]-L-isoleucyl]-L-prolyl]-; L-α-Aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-L-glutamine; H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH; Epidermal Growth Factor Receptor Peptide. Grades: ≥95%. CAS No. 96249-43-3. Molecular formula: C61H93N13O23. Mole weight: 1376.46. | |
| EGF Receptor Substrate 2 Phospho-Tyr5 | EGF Receptor Substrate 2 Phospho-Tyr5 is a bioactive peptide derived from the autophosphorylation site (Tyr992) of the epidermal growth factor receptor (EGFR). Alternative Names: H-Asp-Ala-Asp-Glu-pTyr-Leu-Ile-Pro-Gln-Gln-Gly-OH. Grades: ≥95%. Molecular formula: C54H82N13O24. Mole weight: 1328.28. | |
| EGFRvIII peptide (PEPvIII) | EGFRvIII peptide (PEPvIII), a tumor-specific mutation and a target for anti-tumor immunotherapy, is widely expressed in glioblastoma multiforme (GBM) and other tumors, and its expression enhances tumorigenicity. Alternative Names: H-Leu-Glu-Glu-Lys-Lys-Gly-Asn-Tyr-Val-Val-Thr-Asp-His-Cys-OH; L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-lysyl-glycyl-L-asparagyl-L-tyrosyl-L-valyl-L-valyl-L-threonyl-L-alpha-aspartyl-L-histidyl-L-cysteine. Grades: ≥95%. CAS No. 129112-17-0. Molecular formula: C70H111N19O24S. Mole weight: 1634.81. | |
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