BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| NK-122 | NK-122 is a potential bioactive agent. Uses: A potential bioactive agent. Synonyms: NK122; NK 122; NK-122; 1-(1H-indol-2-yl)-2-methylpropan-2-amine hydrochloride. Grades: ≥98%. CAS No. 3417-71-8. Molecular formula: C12H17ClN2. Mole weight: 224.73. |  |
| NK 252 | NK 252 is a Nrf2 activator. It can induce expression of an antioxidant response element promoter driven reporter gene. Synonyms: NK-252; NK 252; NK252; N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea. Grades: ≥98% by HPLC. CAS No. 1414963-82-8. Molecular formula: C13H11N5O3. Mole weight: 285.26. | |
| NKH 477 | NKH477 is a water-soluble analog of forskolin, which is an adenylyl cyclase activator, but it is sparingly soluble in aqueous solutions. It has both inotropic and vasodilator effects. Uses: Vasodilator agents. Synonyms: NKH 477; NKH477; NKH-477; N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride. Grades: ≥98% by HPLC. CAS No. 138605-00-2. Molecular formula: C27H43NO8.HCl. Mole weight: 546.1. | |
| NKY 80 | NKY80 is a selective inhibitor of adenylyl cyclase 5 with IC50 value of 8.3 μM. Synonyms: NKY80; NKY 80; NKY-80. 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone. Grades: ≥98% by HPLC. CAS No. 299442-43-6. Molecular formula: C12H11N3O2. Mole weight: 229.23. | |
| N-L-γ-glutamyl-L-tyrosine | N-L-γ-glutamyl-L-tyrosine is a dipeptide produced by the catabolism of proteins. Synonyms: Gamma-Glutamyltyrosine; H-gamma-Glu-Tyr-OH; H-Glu(Tyr-OH)-OH. Grades: ≥95%. CAS No. 7432-23-7. Molecular formula: C14H18N2O6. Mole weight: 310.31. | |
| N-Methyl-3,3-Diphenylpropylamine | N-Methyl-3,3-Diphenylpropylamine is an intriguing molecule that exhibits remarkable effects on the central nervous system, acting as a highly potent stimulant. Its usage in research has proven valuable in understanding the transport and regulatory mechanisms of dopamine and norepinephrine. Moreover, its therapeutic potential in addressing complex neurological disorders such as attention deficit hyperactivity disorder and narcolepsy bears considerable promise. Synonyms: (3,3-diphenylpropyl)methylamine; N-METHYL-3,3-DIPHENYLPROPYLAMINE; 3,3-Diphenyl-N-Methylpropylamine; Methyl(3,3-diphenylpropyl)amine; N-Methyl-3,3-diphenyl-1-propanamine; N-Methyl-γ-phenylbenzenepropan-1-amine. Grades: 95%. CAS No. 28075-29-8. Molecular formula: C16H19N. Mole weight: 225.33. | |
| N-methyl-5,6-dihydroxyindole | An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 1-Methyl-1H-indole-5,6-diol; Epinephrine Impurity 8. CAS No. 4821-00-5. Molecular formula: C9H9NO2. Mole weight: 163.17. | |
| (+/-)-N-methylcoclaurine | (+/-)-N-methylcoclaurine is a natural alkaloid compound found in several plants. Synonyms: (+/-)-N-methyl coclaurine; N-Methylcoclaurine; DL-N-methylcoclaurine. CAS No. 1472-62-4. Molecular formula: C18H21NO3. Mole weight: 299.36. | |
| N-Methyl Duloxetine | An impurity of duloxetine, a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Synonyms: (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine; (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine. Grades: 95%. CAS No. 132335-46-7. Molecular formula: C19H21NOS. Mole weight: 311.44. | |
| N-methyl Leukotriene C4 | N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of Leukotriene C4 (LTC4) that is not readily metabolized to LTD4 and LTE4. It acts as a potent and selective CysLT2 receptor agonist. Synonyms: N-methyl LTC4. Grades: ≥97%. CAS No. 131391-65-6. Molecular formula: C31H49N3O9S. Mole weight: 639.8. | |
| N-methyl Mesoporphyrin IX | N-methyl Mesoporphyrin IX is a transition state analog of porphyrin and an inhibitor of ferrochelatase involved in heme synthesis. It has been used as a G-quadruplex DNA specific fluorescent probe for monitoring Aβ fibrillation in living cells. Synonyms: 3-[18-(2-carboxyethyl)-7,12-diethyl-3,8,13,17,22-pentamethyl-23H-porphyrin-2-yl]propanoic acid. Grades: ≥95%. CAS No. 142234-85-3. Molecular formula: C35H40N4O4. Mole weight: 580.72. | |
| N-Methyl-N-hydroxyethyl-p-toluidine | Synonyms: 2-(N-Methyl-p-toluidino)ethanol; Hydroxyethyl methyltolylamine. Grades: 95%. CAS No. 2842-44-6. Molecular formula: C10H15NO. Mole weight: 165.23. | |
| N-Methyl Omeprazole Impurity 1 | N-Methyl Omeprazole Impurity 1 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: N'-Methyl Omeprazole; Omeprazole N-Methyl 5-Methoxy Analog; (5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-1H-benzimidazole; N-Methyl Omeprazole (Mixture of Isomers). Grades: > 95%. CAS No. 89352-76-1. Molecular formula: C18H21N3O3S. Mole weight: 359.44. | |
| N-methyl Protoporphyrin IX | N-methyl Protoporphyrin IX is a transition state analog of porphyrin and a potent inhibitor of protoporphyrin IX ferrochelatase involved in heme synthesis. Synonyms: NMPP; N-methyl PPIX; 7,12-Diethenyl-3,8,13,17,23-pentamethyl-21H,23H-porphine-2,18-dipropanoic acid; 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17,22-pentamethyl-23H-porphyrin-2-yl]propanoic acid. Grades: ≥95%. CAS No. 79236-56-9. Molecular formula: C35H36N4O4. Mole weight: 576.7. | |
| NMS-859 | NMS-859 is very selective (IC50 >10 μM) against all of the AAA ATPases, HSP90 or the 53 kinases tested. NMS-859 was active in a cell proliferation assay, with IC50 values of 3.5 μM and 3.0 μM in HCT116 and HeLa cell lines, respectively. NMS-859 covalently modifies VCP on the active site Cys522 and blocks ATP binding. NMS-859 provided critical validation of VCP as a cancer target, and it raises the possibility that targeting VCP might prevent proteasome inhibitor-resistant tumors from escaping through the aggresome-autophagy pathways and cause them to collapse under the high load of unfolded proteins. Synonyms: NMS-859; NMS 859; NMS859. Grades: >98%. CAS No. 1449236-96-7. Molecular formula: C15H12ClN3O3S. Mole weight: 349.79. | |
| NMS-873 | NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 30 nM. Synonyms: NMS873, NMS-873, NMS 873. CAS No. 1418013-75-8. Molecular formula: C27H28N4O3S2. Mole weight: 520.666. | |
| NMS-P715 | NMS-P715 was found to be highly specific for MPS1, with no other kinases inhibited below an IC50 value of 5 mmol/L and with only 3 kinases inhibited below 10 mmol/L (CK2, MELK, and NEK6), which were not significantly affected by compound preincubation. NMS-P715 promotes massive SAC override with a half-maximal effective concentration (EC50) of 65 nmol/L. NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumoral cell lines and inhibits tumor growth in preclinical cancer models. Synonyms: NMS P715; NMS-P 715. Grades: >98%. CAS No. 1202055-32-0. Molecular formula: C35H39F3N8O3. Mole weight: 676.73. | |
| NMS-P715 Analog | NMS-P715 is a selective and orally bioavailable MPS1 inhibitor, which selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumoral cell lines and inhibits tumor growth in preclinical cancer models. Inhibiting the SAC could represent a promising new approach to selectively target cancer cells. Synonyms: NMS-P715; NMSP715; NMSP-715; NMSP 715. Grades: 0.98. CAS No. 1202055-34-2. Molecular formula: C35H42N8O3. Mole weight: 622.774. | |
| NNC 63-0532 | NNC 63-0532 is a non-peptide agonist for the nociceptin (NOP) receptor (Ki = 7.3 nM, EC50 = 305 nM). Synonyms: 1,3,8-Triazaspiro[4.5]decane-3-acetic acid, 8-(1-naphthalenylmethyl)-4-oxo-1-phenyl-, methyl ester; NNC 63 0532; NNC630532; NNC-63-0532; NNC-630532; 8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetic acid, methyl ester; Methyl 8-(1-naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetate. Grades: ≥98% by HPLC. CAS No. 250685-44-0. Molecular formula: C27H29N3O3. Mole weight: 443.54. | |
| N,N'-Desethylene Levofloxacin | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: 9-Fluoro-2,3-dihydro-3-methyl-10-(2-(methylamino)ethylamino)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine-6-carboxylic acid, (S)-. Grades: > 95%. CAS No. 151250-76-9. Molecular formula: C16H18FN3O4. Mole weight: 335.34. | |
| N,N-Diethyl-2-(1-naphthyloxy)propanamide | Napropamid is a selective systemic amide herbicide which is used against a number of annual grasses and broad-leaved weeds for inhibiting root development and growth. Synonyms: N,N-diethyl-2-naphthalen-1-yloxypropanamide. CAS No. 15299-99-7. Molecular formula: C17H21NO2. Mole weight: 271.35. | |
| N,N-diethyl-2-((6-methylpyridin-2-yl)methylene)hydrazinecarbothioamide | N, N-diethyl-2- ( (6-methylpyridin-2-yl) methylene) hydrazinecarbothioamide, a chemically-complex compound, is gaining recognition in biomedicine as a viable drug candidate for treating a range of ailments. Notably, research suggests that it possesses considerable anti-inflammatory, analgesic, and antioxidant activity that could hold promise in combatting conditions such as arthritis and other inflammatory disorders. Nevertheless, comprehensive studies are necessary to ascertain its optimal therapeutic capacity. Synonyms: Hydrazinecarbothioamide, N,N-diethyl-2-[(6-methyl-2-pyridinyl)methylene]-. Grades: ≥98%. CAS No. 210700-64-4. Molecular formula: C12H18N4S. Mole weight: 250.36. | |
| N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine | N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine, also called 2-Ethylaminoatrazine, under the IUPAC name 2-Ethylaminoatrazine, can be used as insecticide and herbicide. Uses: Insecticide; herbicide. Synonyms: 4-N,6-N-diethyl-2-N-propan-2-yl-1,3,5-triazine-2,4,6-triamine; 30360-19-1; N,N'-Diethyl-N''-isopropyl-1,3,5-triazine-2,4,6-triamine; 2,4-Bis(ethylamino)-6-isoproylamino-1,3,5-triazine; EINECS 250-146-6; 2-Ethylaminoatrazine; 2-(Ethylamino)atrazine; AC1L1SY9; SCHEMBL11452149; ZINC2011064; Melamine, N2,N4-diethyl-N6-isopropyl-; HE048494; N2,N4-DIETHYL-N6-ISOPROPYLMELAMINE; 3B1-004129; 4-N,6-N-diethyl-2-N-propan-2-yl-1,3,5-triazine-2,4,6-triamine; N N'-DIETHYL-N''-ISOPROPYL-1 3 5-TRIAZINE-2 4 6-TRIAMINE; N2,N4-diethyl-N6-(propan-2-yl)-1,3,5-triazine-2,4,6-triamine. Grades: ≥ 95.0%. CAS No. 30360-19-1. Molecular formula: C10H20N6. Mole weight: 224.31. | |
| N,N'-Difurfuryloxamide | N,N'-Difurfuryloxamide, an organic compound of paramount significance used as a crucial forerunner in the creation of sundry medicines and pharmaceuticals. Distinguished by its notable anti-inflammatory and antimicrobial traits, it exhibits extensive promise as an agent amenable for treating multiple ailments like gingivitis and periodontitis. Synonyms: N,N'-bis(furan-2-ylmethyl)ethanediamide; N,N'-difurfuryl-oxalamide. CAS No. 69010-90-8. Molecular formula: C12H12N2O4. Mole weight: 248.238. | |
| N,N'-Dimethyl-2,7-diazapyrenium difluoroborate | N,N'-Dimethyl-2,7-diazapyrenium difluoroborate (CAS# 21178-14-3 ) is a useful research chemical. Synonyms: 2,7-Dimethyl-benzo[lmn][3,8]phenanthrolinium bistetrafluoroborate. CAS No. 21178-14-3. Molecular formula: C16H14B2F8N2. Mole weight: 407.9. | |
| N,N-dimethyldodecan-1-amine oxide | N,N-dimethyldodecan-1-amine oxide is a frequently-used amine oxide surfactant. It is strongly hydrophilic, and it forms normal micelles and normal liquid crystalline phases. Synonyms: LDAO; Lauramine oxide; Lauryldimethylamine oxide; Dodecyldimethylamine oxide; Lauryldimethylamine N-oxide. Grades: > 99 %. CAS No. 1643-20-5. Molecular formula: C14H31NO. Mole weight: 229.40. | |
| N,N-Dimethyl-L-Tyrosine | N,N-Dimethyl-L-Tyrosine, a derivative of the amino acid tyrosine, has been a subject of interest in the research field due to its key role in elucidating amino acid metabolism. Additionally, it has been extensively studied for its precursor role in the synthesis of well-known neurotransmitters like dopamine and norepinephrine, thereby finding novel therapeutic applications in the treatment of neurodegenerative disorders such as Parkinson's disease and depression. The significance of this chemical compound could not be overstated in the realm of medicinal research. Synonyms: n,n-dimethyltyrosine; dimethyltyrosine; L-Tyrosine, N,N-dimethyl-. CAS No. 17350-74-2. Molecular formula: C11H15NO3. Mole weight: 209.24. | |
| N,N-dimethyloctadecanamide | N,N-dimethyloctadecanamide (CAS# 3886-90-6 ) is a useful research chemical. Synonyms: N,N-Dimethyloctadecanamide; N N-Dimethyl-9-octadecenamide; Hallcomid M 18. Grades: 95 %. CAS No. 3886-90-6. Molecular formula: C20H41NO. Mole weight: 311.5. | |
| N,N-Dimethylsphingosine | N,N-Dimethylsphingosine has been found to be a competitive sphingosine kinase (SphK) inhibitor and could implicate in neuropathic pain. Uses: Enzyme inhibitors. Synonyms: N,N-dimethyl-D-erythro-sphingosine; N,N-Dimethylsphing-4-Enine; Dimethyl Sphingosine (d18:1). Grades: >99%. CAS No. 119567-63-4. Molecular formula: C20H41NO2. Mole weight: 327.55. | |
| N,N'-Ethylenebisoleamide | N,N'-Ethylenebisoleamide is a compound with surfactant and emulsifying properties, extensively used in biomedicine. Its multipurpose functionality includes being an antifungal, anticancer and antiviral agent, and its feasibility against life-altering diseases such as HIV, influenza, and cancer are being researched. Synonyms: Ethylene dioleamide; N,N'-1,2-Ethanediylbis-9-octadecenamide. CAS No. 110-31-6. Molecular formula: C38H72N2O2. Mole weight: 588.99. | |
| N-Nitrosohexamethyleneimine | N-Nitrosohexamethyleneimine (CAS# 932-83-2 ) is a useful research chemical. Synonyms: N-Nitrosoperhydroazepine; Nitrosohexamethylenimine. CAS No. 932-83-2. Molecular formula: C6H12N2O. Mole weight: 128.17. | |
| N-Nitroso Tamsulosin | An impurity of Tamsulosin, which is an α1-adrenoceptor antagonist and could be used against benign prostatic hypertrophy. Synonyms: (R)-5- (2- ( (2- (2-ethoxyphenoxy)ethyl) (nitroso)amino)propyl)-2-methoxybenzenesulfonamide. Molecular formula: C20H27N3O6S. Mole weight: 437.51. | |
| N,N,N',N'-Tetramethyl-1,5-pentanediamine | N,N,N',N'-Tetramethyl-1,5-pentanediamine (CAS# 44994-28-7 ) is a useful research chemical. Synonyms: 1,5-bis(dimethylamino)pentane. CAS No. 44994-28-7. Molecular formula: C9H22N2. Mole weight: 158.28. | |
| N,N'-Thiobisphthalimide | Synonyms: n,n'-thio-bis(phthalimide); N,N'-Thiodiphthalimide; 2,2'-thiobis(isoindoline-1,3-dione); 2-(1,3-dioxoisoindol-2-yl)sulfanylisoindole-1,3-dione. CAS No. 7764-29-6. Molecular formula: C16H8N2O4S. Mole weight: 324.31. | |
| NO-1886 | NO-1886 is a lipoprotein lipase (LPL) activator that increases the level of high-density lipoprotein cholesterol and reduces plasma triglycerides. It was shown to prevent fat accumulation in high fat-fed rats, suggesting its potential use as an antidiabetic agent. Synonyms: Ibrolipim; Lipoprotein Lipase Activator; LPL Activator; OPF 009; N-(4-bromo-2-cyanophenyl)-4-(diethoxyphosphorylmethyl)benzamide. Grades: ≥98%. CAS No. 133208-93-2. Molecular formula: C19H20BrN2O4P. Mole weight: 451.3. | |
| Nociceptin | Nociceptin, a 17 amino acid neuropeptide involved in a variety of biological systems, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic. Synonyms: Orphanin FQ; H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH; L-phenylalanyl-glycyl-glycyl-L-phenylalanyl-L-threonyl-glycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparagyl-L-glutamine; Nociceptin/orphanin FQ; Nociceptin (1-17); Orphanin FQ (rat, human, swine). Grades: ≥98% by HPLC. CAS No. 170713-75-4. Molecular formula: C79H129N27O22. Mole weight: 1809.04. | |
| Nocistatin (bovine) | Nocistatin (bovine) is a peptide derived from the same precursor as nociceptin, and acts as a negative control of nociceptin. It blocks nociceptin-induced allodynia and hyperalgesia, and attenuates pain evoked by prostaglandin E2. Synonyms: Nocistatin (bovine); 208253-85-4; AKOS024456394; NCGC00167175-01; PD079088. CAS No. 208253-85-4. Molecular formula: C82H135N21O32. Mole weight: 1927.07. | |
| Nodakenin | Nodakenin is an important natural resource and medicinal material with anti-allergic and anti-inflammatory activities. Synonyms: (+)-Marmesinin. Grades: >98%. CAS No. 495-31-8. Molecular formula: C20H24O9. Mole weight: 408.4. | |
| Nodularin | Nodularin is a pentapeptide toxin produced by the cyanobacterium Nodularia spumigena. It acts as a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. Synonyms: Nodularin; Nodularin R; Nodularin-R; UNII-0979BIK2QU; 0979BIK2QU; HSDB 7749; DTXSID60880022; (2Z,5R,6S,9S,12S,13S,16R)-9-[3-(diaminomethylideneamino)propyl]-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,6,13-trimethyl-3,7,10,14,19-pentaoxo-1,4,8,11,15-pentazacyclononadecane-5,16-dicarboxylic acid; Cyclo((Z)-2,3-didehydro-N-methyl-2-aminobutanoyl-erythro-3-methyl-D-beta-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyl-3-aminodecanoyl-D-gamma-glutamyl); Nodularin, cyanotoxin. Grades: ≥95%. CAS No. 118399-22-7. Molecular formula: C41H60N8O10. Mole weight: 825. | |
| Nonacosan-15-one | Nonacosan-15-one (CAS# 2764-73-0 ) is a useful research chemical. Synonyms: nonacosan-15-one; 15-Nonacosanone; Nonacosan-15-one; 2764-73-0; AC1L2PYV; AC1Q5H9Q. Grades: 95 %. CAS No. 2764-73-0. Molecular formula: C29H58O. Mole weight: 422.77. | |
| Nonapeptide-1 | Nonapeptide-1 is a skin lightening peptide that prevents melanin synthesis and unwanted pigmentation. It is used as an additive in whitening or spot corrective products. Uses: Skin lightening additive. Synonyms: Melanostatine; Oxytocin Intermediate-nine peptide. CAS No. 158563-45-2. Molecular formula: C61H87N15O9S. Mole weight: 1206.523. | |
| Nonoxynol-5 | Nonylbenzene-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker. Nonylbenzene-PEG5-OH can be used in the synthesis of a series of PROTACs. CAS No. 20636-48-0. Molecular formula: C25H44O6. Mole weight: 440.61. | |
| Noradrenaline bitartrate monohydrate | Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator. Noradrenaline modulates the gain of evoked activity, especially in sensory areas. Synonyms: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol Hydrogen Tartrate Monohydrate; L-Noradrenaline Bitartrate Monohydrate; Levoarterenol Bitartrate Monohydrate; L-Arterenol Bitartrate Monohydrate; 1,2-Benzenediol, 4-[(1R)-2-amino-1-hydroxyethyl]-, (2R,3R)-2,3-dihydroxybutanedioate, hydrate (1:1:1); 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt), monohydrate; Arterenol, tartrate, monohydrate. Grades: >98%. CAS No. 108341-18-0. Molecular formula: C12H19NO10. Mole weight: 337.28. | |
| Norepinephrine hydrochloride | Adrenal medullary stress hormone, mediator of the fight-or-flight response; and the primary neurotransmitter in the post-ganglionic sympathetic (adrenergic) nervous system. Uses: Adrenergic alpha-agonists. Synonyms: L-Arterenol hydrochloride, L-Noradrenaline hydrochloride. Grades: >98%. CAS No. 329-56-6. Molecular formula: C8H12ClNO3. Mole weight: 205.64. | |
| Norharmane | Norharmane is a potent IDO inhibitor. Synonyms: 9H-Pyrido[3,4-b]indole. Grades: > 98%. CAS No. 244-63-3. Molecular formula: C11H8N2. Mole weight: 168.19. | |
| Norharmane hydrochloride | Norharmane hydrochloride is a potent IDO inhibitor. Synonyms: β-Carboline; 9H-Pyrido(3,4-b)indole. Grades: > 98%. CAS No. 7259-44-1. Molecular formula: C11H8N2 HCl. Mole weight: 204.66. | |
| Norhyoscyamine sulfate | Norhyoscyamine sulfate, a potent anticholinergic agent, exerts its therapeutic effects through the inhibition of acetylcholine activity, which makes it a valuable treatment option for several types of gastrointestinal disorders, such as motility disorders, as well as urinary incontinence. Moreover, this multifaceted medication exhibits remarkable preoperative benefits, as it can effectively reduce both respiratory and digestive secretions, underscoring its versatility and potential for widespread clinical use. Synonyms: Norhyoscyamine. CAS No. 537-29-1. Molecular formula: C16H21NO3. Mole weight: 275.34. | |
| Norisoboldine | Norisoboldine might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. Synonyms: norisoboldine; (+)-Laurelliptine; (+)-N-Norisoboldine; (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-4H-dibenzo[de,g]quinoline-1,9-diol; (S)-(+)-Laurelliptine. Grades: >98%. CAS No. 23599-69-1. Molecular formula: C18H19NO4. Mole weight: 313.35. | |
| nor-NOHA acetate | nor-NOHA is a reversible inhibitor of rat liver arginase from rat liver and mouse macrophages. Synonyms: Nω-hydroxy-nor-arginine diacetate salt; Nω-hydroxy-nor-L-arginine diacetate salt. Grades: ≥97%. CAS No. 1140844-63-8. Molecular formula: C5H12N4O3·2C2H4O2. Mole weight: 296.3. | |
| Nor NOHA monoacetate | Cas No. 2250019-93-1. | |
| Novaluron | Novaluron is a chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators. It inhibits chitin formation, targeting specifically larval insect stages that actively synthesize chitin. Grades: >98%. CAS No. 116714-46-6. Molecular formula: C17H9ClF8N2O4. Mole weight: 492.7. | |
| n-Propyl Dioxepin | N-Propyl Dioxepin, a chemical compound, has been found to hold immense potential in the field of neuroscience due to its ability to be leveraged in the creation of new pharmaceuticals that are aimed at treating a range of neurological disorders, including but not limited to Alzheimer's disease and schizophrenia. This compound has been shown to be a wonderfully proficient antagonist of the dopamine receptors, as evidenced by preclinical studies. Synonyms: 2-Propyl-4,7-dihydro-1,3-dioxepine. CAS No. 4469-34-5. Molecular formula: C8H14O2. Mole weight: 142.198. | |
| N-Propylmaleimide | Synonyms: 1-Propyl-1H-pyrrole-2,5-dione; N-(n-propyl)maleimide. Grades: 95 %. CAS No. 21746-40-7. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| NQ 301 | NQ 301 is a CD45 inhibitor with IC50 value of 200 nM. It can block inflammation in a delayed-type hypersensitivity model in vivo. Synonyms: NQ-301; NQ 301; NQ301. 2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione. Grades: ≥98% by HPLC. CAS No. 130089-98-4. Molecular formula: C18H12ClNO3. Mole weight: 325.75. | |
| N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide | N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide, an intriguing chemical substance, has garnered interest in the biomedical domain as a plausible remedy for assorted cancer types. This compound exerts its therapeutic effects by curbing certain enzymes and provoking apoptosis in malignant cells, thereby causing their demise. Although promising, further scientific investigations and clinical deliberations are fundamental to ascertain its potency and risk profiles. Grades: 98.0%. Molecular formula: C22H16N6O2S. Mole weight: 428.474. | |
| NS 2028 | S-2028 is a soluble guanylyl cyclase inhibitor. It can inhibit purified bovine lung guanylyl cyclase with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes. Synonyms: NS 2028; NS-2028; NS2028; 8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one. Grades: ≥98% by HPLC. CAS No. 204326-43-2. Molecular formula: C9H5BrN2O3. Mole weight: 269.05. | |
| NS-2214 | NS-2214, an azabicyclo compound, has been found to be a dopamine uptake inhibitor that was once studied in the treatment of Parkinson's disease. Synonyms: Brasofensine sulfate; BMS 204756; BMS-204756; NS 2214; NS2214; NS-2214; (E)-1-[(1R,3S,4R,5R)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]-N-methoxymethanimine;sulfuric acid. Grades: 98%. CAS No. 171655-92-8. Molecular formula: C16H22Cl2N2O5S. Mole weight: 425.32. | |
| NS 3763 | NS 3763 is a non-competitive kainate receptor antagonist of GLUK5 subunit-containing receptors (IC50 = 1.6 mM)) without disrupting GLU(K6) subtype (IC50 > 30 microM). Besides, NS 3763 has minimal activity at AMPA and NMDA receptors (IC50 > 30 μM). Synonyms: NS3763; NS 3763; NS-3763. 1,?3-Benzenedicarboxylic acid, 4,?6-bis(benzoylamino)?-; 4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid; 4,6-Dibenzamidoisophthalic acid. CAS No. 70553-45-6. Molecular formula: C22H16N2O6. Mole weight: 404.37. | |
| NSC134754 | NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. NSC134754 can also completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells. Uses: Amti-tumor. Synonyms: NZ-28; NZ28; NZ 28; NSC 134754; NSC 134754; NSC134754. (S)-3-ethyl-9,10-dimethoxy-2-(((R)-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline. Grades: 98%. CAS No. 75041-32-6. Molecular formula: C27H34N2O2. Mole weight: 418.58. | |
| NSC 146109 hydrochloride | NSC 146109 hydrochloride is a genotype-selective antitumor agent. It can activate p53-dependent transcription. Synonyms: NSC 146109 hydrochloride; NSC146109 hydrochloride; NSC-146109 hydrochloride; (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride. Grades: ≥99% by HPLC. CAS No. 59474-01-0. Molecular formula: C17H16N2S.HCl. Mole weight: 316.85. | |
| NSC 185058 | NSC 185058 is an inhibitor of ATG4B that inhibits ATG4B activity in vitro and in cells with no effect against MTOR and PtdIns3K. It inhibited autophagy and exhibited a negative impact on the development of Saos-2 osteosarcoma tumors in vivo. Synonyms: N-(pyridin-2-yl)pyridine-2-carbothioamide. Grades: ≥98%. CAS No. 39122-38-8. Molecular formula: C11H9N3S. Mole weight: 215.3. | |
| NSC 23005 sodium | NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Synonyms: NSC 23005 sodium; NSC23005 sodium; NSC-23005 sodium; 4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 1796596-46-7. Molecular formula: C13H16NNaO4S. Mole weight: 305.33. | |
| NSC 23005 Sodium Salt | Cas No. 6314-70-1. | |
| NSC 23766 | NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase. It does not inhibit the closely related targets, Cdc42 or RhoA. Synonyms: NSC 23766; NSC23766; NSC-23766. Grades: >98%. CAS No. 733767-34-5. Molecular formula: C24H35N7. Mole weight: 421.58. | |
| NSC 23766 trihydrochloride | NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Synonyms: NSC 23766 (trihydrochloride); NSC23766 (trihydrochloride); NSC-23766 (trihydrochloride); N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride. Grades: ≥98%. CAS No. 1177865-17-6. Molecular formula: C24H38Cl3N7. Mole weight: 530.967. | |
| NSC 23925 | NSC 23925 is a potent plasma membrane glycoprotein 1 (Pgp1) inhibitor that reverses multidrug resistance (MDR1) mediated by Pgp1 without inhibitory effect against MRP or BCRP-mediated MDR1. NSC 23925 can prevent MDR1 in ovarian cancer both in vitro and in vivo. Synonyms: (2-(4-methoxyphenyl)quinolin-4-yl)(piperidin-2-yl)methanol dihydrochloride. Grades: ≥98%. CAS No. 858474-14-3. Molecular formula: C22H24N2O2·2HCl. Mole weight: 421.4. | |
| NSC348884 | NSC 348884 is a putative inhibitor of nucleophosmin (NPM). It is a small molecule that inhibits the formation of nucleophosmin dimers by disrupting a defined hydrophobic pocket required for oligomerization. It can inhibit cell proliferation,up-regulates p53 and induce apoptosis in various cancer cell lines with IC50 values ranging from 1.4-4 μM. It disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. Uses: Nsc 348884 inhibits the formation of nucleophosmin dimers. it can inhibit cell proliferation,up-regulates p53 and induce apoptosis in various cancer cell line. it disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. Synonyms: NSC348884; NSC 348884; NSC-348884; N1,N1,N2,N2-Tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]-1,2-ethanediamine;1,2-EthanediaMine, N,N,N',N'-tetrakis[(5-Methyl-1H-benziMidazol-2-yl)Methyl]- ;N,N,N',N'-tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]ethane-1,2-diamine. Grades: >98%. CAS No. 81624-55-7. Molecular formula: C38H40N10. Mole weight: 636.79. | |
| NSC-41589 | N-[2-(methylsulfanyl) phenyl]acetamide. Synonyms: NSC-41589; NSC 41589; NSC41589. Grades: >98%. CAS No. 6310-41-4. Molecular formula: C9H11NOS. Mole weight: 181.25. | |
| NSC-601980 analog | NSC-601980 analog is the analog of the NSC601980, which shows antitumor activity in the yeast screening experiment. Synonyms: NSC601980 analog; NSC 601980 analog; NSC-601980 analog. Grades: >98%. CAS No. 91757-46-9. Molecular formula: C15H14N4. Mole weight: 250.30. | |
| NSC 617145 | NSC 617145 is a werner syndrome helicase inhibitor with IC50 value of 250 nM. It is used as an antineoplastic. Synonyms: 1,1'-(2,2-dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-Pyrrole-2,5-dione. Grades: ≥98% by HPLC. CAS No. 203115-63-3. Molecular formula: C13H10Cl4N2O4. Mole weight: 400.04. | |
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