BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Oleanolic acid - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside | Oleanolic acid - 3-O-β-D- Galactosyl( 1?3)-β-D-glucosyl( 1?3)-α-L-rhamnosyl(1?2)-α-L-arabinoside is a lupane-type triterpenoid glycoside isolated from Pulsatilla chinensis BungeRegel. Grades: > 98%. Molecular formula: C53H86O21. Mole weight: 1059.24. |  |
| Oleanolic acid 3-O-β-D-glucosyl-( 1?3)-α-L-ramnosyl(1?2)-α-L-arabinoside | Oleanolic acid 3-O-β-D-glucosyl-( 1?3)-α-L-ramnosyl(1?2)-α-L-arabinoside is extracted from Pulsatilla chinensis (Bunge) Regel. Synonyms: 3-[(O-beta-D-Glucopyranosyl-(1?3)-O-6-deoxy-alpha-L-mannopyranosyl-(1?2)-alpha-L-arabinopyranosyl)oxy]-olean-12-en-28-oic acid. Grades: >98%. CAS No. 103956-33-8. Molecular formula: C47H76O16. Mole weight: 897.1. | |
| Oleoyl-D-lysine sodium salt | Oleoyl-D-lysine is a potent and selective inhibitor of glycine transporter 2a (GlyT2a). It may be potentially used as an analgesic. Grades: ≥98%. Molecular formula: C24H46N2O3·Na. Mole weight: 433.62. | |
| Oleyl anilide | Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransferase (ACAT), an intracellular protein located in the endoplasmic reticulum that forms cholesteryl esters. OA and the related glyceride dioleoyl phenylamino propane 1,2-diol have been linked to a syndrome of eosinophilia, excessive T-cell activation, and elevated interleukin-4 (IL-4), soluble IL-2R, and IL-5. Synonyms: OA; Oleic acid anilide; Cis-9-octadecenanilide; (Z)-N-phenyloctadec-9-enamide. Grades: ≥95%. CAS No. 5429-85-6. Molecular formula: C24H39NO. Mole weight: 357.6. | |
| Oligopeptide-3 | A cosmetic indegredient. Grades: 95%. | |
| Olinciguat | Olinciguat is an oral guanylate cyclase (sGC) stimulant. Synonyms: IW-1701; PD5F4ZXD21; IW1701. Grades: ≥98% by HPLC. CAS No. 1628732-62-6. Molecular formula: C21H16F5N7O3. Mole weight: 509.4. | |
| Olmesartan Dimer Ester Impurity | A metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50=6.12 nM. Synonyms: OlMesartan DiMer Ester Impurity; 4-{2-[4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carbonyloxy]propan-2-yl}-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylic acid. Grades: > 95%. CAS No. 1040250-19-8. Molecular formula: C48H50N12O5. Mole weight: 875.01. | |
| Olmesartan Impurity 13 | One of the impurities of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Synonyms: 5-(4'-(BROMOMETHYL)-[1,1'-BIPHENYL]-2-YL)-2H-TETRAZOLE. Grades: 95%. CAS No. 138402-33-2. Molecular formula: C14H11BrN4. Mole weight: 315.17. | |
| Olmesartan Medoxomil Impurity C | Cas No. 879562-26-2. | |
| Olmesartan Medoxomil Related Compound A | Cas No. 849206-43-5. | |
| Olumacostat glasaretil | OG (Olumacostat glasaretil) is a acetyl-coenzyme A carboxylase inhibitor. Acetyl-COA carboxylase is the key point for the first, rate-limiting step in de novo fatty acid synthesis. OG can inhibit in vitro human sebocyte lipid production, it can also reduce in vivo sebaceous gland size in hamster ears. Synonyms: Olumacostat glasaretil; DRM01B; DRM-01B; DRM 01B. 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate. Grades: 98%. CAS No. 1261491-89-7. Molecular formula: C26H43NO7. Mole weight: 481.63. | |
| Olvanil | Olvanil is vanilloid receptor agonist which can induce desensitization analgesia in rat and mouse models of pain. It is also a CB1 agonist. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N-Vanillyloleoylamide. Grades: ≥98% by HPLC. CAS No. 58493-49-5. Molecular formula: C26H43NO3. Mole weight: 417.63. | |
| Omadacycline hydrochloride | Omadacycline hydrochloride is the hydrochloride salt of Omadacycline which is the first intravenous and oral 9-aminomethylcycline in clinical development for multiple infectious disease indications. Synonyms: (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-9-[(2,2-dimethylpropylamino)methyl]-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride; Omadacycline (hydrochloride). CAS No. 1196800-39-1. Molecular formula: C29H40N4O7.HCl. Mole weight: 593.11. | |
| Ombrabulin hydrochloride | Ombrabulin hydrochloride is the hydrochloride salt form of Ombrabulin. Ombrabulin, also called as AVE8062, a synthetic water-soluble analogue of CA-4-P, binds to the colchicine binding site of endothelial cell tubulin, and induces G2/M arrest, thus bringi. Synonyms: AC 7700; AC7700; AC-7700; Ombrabulin HCl; 2-amino-3-hydroxy-N-[2-methoxy-5-[2- (3, 4, 5-trimethoxyphenyl) ethenyl]phenyl]propanamide; hydrochloride253426-24-3 (S) -N- (5- (3, 4, 5-TRIMETHOXYSTYRYL) -2-METHOXYPHENYL) -2-AMINO-3-HYDROXYPROPANAMIDE HYDROCHLORIDEA8177972-amino-3-hydroxy-N-[2-methoxy-5-[2-(3,4. CAS No. 253426-24-3. Molecular formula: C21H27ClN2O6. Mole weight: 438.9. | |
| OMDM-2 | OMDM-2 is a selective inhibitor of anandamide cellular uptake. It can inhibit the cellular uptake of tritiated AEA with IC50 value of 3 μM. Synonyms: (9Z)-N-[1-((R)-4-Hydroxbenzyl)-2-hydroxyethyl]-9-octadecenamide. Grades: ≥99% by HPLC. CAS No. 616884-63-0. Molecular formula: C27H45NO3. Mole weight: 431.66. | |
| Omecamtiv mecarbil | Omecamtiv mecarbil is a cardiac-specific myosin activator with an EC50 of 0.6 μM. Synonyms: Omecamtiv mecarbil; CK1827452; CK 1827452; CK1827452. Grades: >98%. CAS No. 873697-71-3. Molecular formula: C20H24FN5O3. Mole weight: 401.43. | |
| omega conotoxin MVIIA | ω conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). Synonyms: Ziconotide; Prialt. Grades: 98%. CAS No. 107452-89-1. Molecular formula: C102H172N36O32S7. Mole weight: 2639.2. | |
| Omeprazole Impurity 13 | Omeprazole Impurity 13 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 4-Desmethoxy-4-Chloro Omeprazole Sulfide; 5-Methoxy-2-[[(4-Chloro-3,5-Dimethylpyridin-2-yl)methyl]sulphanyl]-1H-Benzimidazole. Grades: >97%. CAS No. 220757-74-4. Molecular formula: C16H16ClN3OS. Mole weight: 333.84. | |
| Omeprazole Impurity B | Cas No. 110374-16-8. | |
| Omeprazole Impurity C | Cas No. 73590-85-9. | |
| Omeprazole Impurity D | Cas No. 88546-55-8. | |
| Omeprazole Impurity E | Cas No. 176219-04-8. | |
| Omeprazole Impurity F | Cas No. 125656-82-8. | |
| Omeprazole Impurity G | Cas No. 125656-83-9. | |
| Omeprazole Impurity H | Cas No. 863029-89-4. | |
| Omeprazole Impurity I | Cas No. 158812-85-2. | |
| Omeprazole Related Compound 10 | Omeprazole Related Compound 10 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 4-Methoxy-2-(((5-methoxy-1H-benzo[d]imidazol-2-yl)thio)methyl)-3,5-dimethylpyridine 1-oxide; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxo-2-pyridinyl)methyl]sulfanyl]-1H-benzimidazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide. Grades: >95%. CAS No. 142885-92-5. Molecular formula: C17H19N3O3S. Mole weight: 345.42. | |
| Omeprazole Related Compound 15 | Omeprazole Related Compound 15 is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Uses: Impurity c from the synthesis of omeprazole. Synonyms: 4-Desmethoxy-4-nitro Omeprazole; 2-[[(3,5-Dimethyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole; 5-Methoxy-2-{(S)-[(4-nitro-3,5-dimethyl-pyridine-2-yl)methyl]sulfinyl}-1H-benzimidazole; rac 4-Desmethoxy-4-nitro Omeprazole. Grades: >98%. CAS No. 317807-10-6. Molecular formula: C16H16N4O4S. Mole weight: 360.39. | |
| O-Methyl Atorvastatin Calcium Salt | O-Methyl Atorvastatin Calcium Salt is atorvastatin derivative. Synonyms: (βR,δR)-2-(4-Fluorophenyl)-δ-hydroxy-β-Methoxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid CalciuM Salt; Atorvastatin EP impurity G. Grades: > 95%. CAS No. 887196-29-4. Molecular formula: C34H37FN2O5Ca1/2. Mole weight: 591.71. | |
| ON-013100 | ON-013100, a cell cycle inhibitor, altered the growth and cell cycle status of MCL lines and potently inhibited the expression of several important molecules, including cyclin-dependent kinase 4, p53, mouse double minute 2 (MDM2), and cyclin D as well as increased cyclin B expression. Synonyms: (E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol; ON-013100; ON 013100; ON013100. CAS No. 865783-95-5. Molecular formula: C19H22O7S. Mole weight: 394.43. | |
| Onjisaponin B | Onjisaponin B is extracted from the roots of Polygala tenuifolia. It was able to induce autophagy and accelerate both the removal of mutant huntingtin and A53T α-synuclein, which are highly associated with Huntington disease and Parkinson disease, respectively. It induces autophagy via the AMPK-mTOR signaling pathway. It increased the NGF level and may have potential therapeutic effects for the treatment of Alzheimer disease patients. Synonyms: Senegin III; Sinegin 3. Grades: >98%. CAS No. 35906-36-6. Molecular formula: C75H112O35. Mole weight: 1573.7. | |
| Ono-1082 | Ono-1082 increases cAMP levels in hepatocytes in rats. Synonyms: Ono1082; Ono-1082; Ono 1082; N-(7-((1R,2R,3R)-2-((1E,3S)-3-((1S,3S)-3-Butylcyclopentyl)-3-hydroxy-1-propenyl)-3-hydroxy-5-oxocyclopentyl)-1,6-dioxoheptyl)-L-leucine;(2S)-2-[[7-[(2R,3R)-2-[(E,3S)-3-(3-butylcyclopentyl)-3-hydroxyprop-1-enyl]-3-hydroxy-5-oxocyclopentyl]-6-oxoheptanoyl]amino]-4-methylpentanoic acid;Ono1082;(S)-2-(7-((1R,2R,3R)-2-((S,E)-3-((1S,3S)-3-butylcyclopentyl)-3-hydroxyprop-1-en-1-yl)-3-hydroxy-5-oxocyclopentyl)-6-oxoheptanamido)-4-methylpentanoic acid. Grades: >98%. CAS No. 111111-04-7. Molecular formula: C30H49NO7. Mole weight: 535.72. | |
| ONO-1301 | ONO-1301, a naphthalen derivative, has been found to be a prostacyclin agonist and could be studied as an anti-inflammatory agent works partially through leading the formation of hepatocyte growth factor. Synonyms: Ono1301; Ono-1301; Ono 1301; 7,8-Dihydro-5-[(E)-[[-(3-pyridyl)benzylidene]aminooxy]ethyl]-1-naphthyloxy]acetic acid. Grades: 98%. CAS No. 176391-41-6. Molecular formula: C27H26N2O4. Mole weight: 428.48. | |
| ONO3708 | ONO3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo. It could play an important role in the pathogenesis of thrombosis and may be of therapeutic use in preventing cerebral vasospasm. It has therapeutic advantages in preventing thrombosis. Uses: Ono3708 may be of therapeutic use in preventing cerebral vasospasm. it has therapeutic advantages in preventing thrombosis. Synonyms: Ono3708; Ono-3708; Ono 3708;5-Heptenoic acid, 7-((1S,2S,3S,5R)-3-(((2R)-cyclopentylhydroxyacetyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-, (5Z)-;(Z)-7-[(1R,3S,4S,5S)-3-[[(2R)-2-cyclopentyl-2-hydroxyacetyl]amino]-6,6-dimethyl-4-bicyclo[3.1.1]heptanyl]hept-5-enoic acid. Grades: >98 %. CAS No. 102191-05-9. Molecular formula: C23H37NO4. Mole weight: 391.55. | |
| Ono-4007 sodium salt | Cas No. 152646-95-2. | |
| ONO-7300243 | ONO-7300243 is a novel, potent LPA1 (Lysophosphatidic Acid Receptor) antagonist (IC50 = 160 nM). In vitro ONO-7300243 showed good membrane permeability and good metabolic stability against rat liver microsomes. ONO-7300243 shows good efficacy in vivo. Synonyms: 2-[4-[[ (3, 5-dimethoxy-4-methylbenzoyl) - (3-phenylpropyl) amino]methyl]phenyl]acetic acid; ONO-7300243; ONO 7300243; ONO7300243. Grades: 99.52 %. CAS No. 638132-34-0. Molecular formula: C28H31NO5. Mole weight: 461.55. | |
| ONO 8130 | ONO 8130 is a prostanoid EP1 receptor antagonist. It can relieve bladder pain in mice with cyclophosphamide-induced cystitis. Synonyms: ONO8130; ONO 8130; ONO-8130; 4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 459841-96-4. Molecular formula: C25H28N2O5S2. Mole weight: 500.63. | |
| ONO EI-601 | ONO EI-601, a sulfonylamine derivative, is one metabolite of ONO-5046 which is a neutrophil elastase inhibitor that could be effective against acute lung injury. Synonyms: Ono-EI-601; OnoEI601; Ono EI 601; Ono-EI 601; Ono EI-601; AC1MHG4J; N- (2- (p-Hydroxyphenylsulfonylamino) benzoyl) glycine; N- (2- ( ( (4-Hydroxyphenyl) sulfonyl) amino) benzoyl) glycine. Grades: 98%. CAS No. 155023-59-9. Molecular formula: C15H14N2O6S. Mole weight: 350.35. | |
| Opicapone | Opicapone is a long-acting, peripherally selective inhibitor of catechol-O-methyltransferase. Synonyms: BIA 9-1067; BIA 91067; BIA-91067; BIA91067; Opicapone. Grades: >98%. CAS No. 923287-50-7. Molecular formula: C15H10Cl2N4O6. Mole weight: 413.17. | |
| Org 25543 hydrochloride | Org 25543 hydrochloride is a glycine transporter type 2 inhibitor with IC50 value of 16 nM. Synonyms: Benzamide, N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)-, hydrochloride (1:1); Benzamide, N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)-, monohydrochloride; 4-(benzyloxy)-N-((1-(dimethylamino)cyclopentyl)methyl)-3,5-dimethoxybenzamide hydrochloride; Org25543 hydrochloride; Org-25543 hydrochloride. Grades: ≥99% by HPLC. CAS No. 495076-64-7. Molecular formula: C24H32lN2O4.HCl. Mole weight: 448.98. | |
| Orientin | Orientin, that can be found in the herbs of Polygonum orientale Linn, exerts antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. Besides, Orientin may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. Uses: Antidepressant. Synonyms: 8-b-D-Glucopyranosyl-3,4,7-tetrahydroxyflavone; Luteolin 8-C-b-D-glucopyranoside; Lutexin. Grades: >98%. CAS No. 28608-75-5. Molecular formula: C21H20O11. Mole weight: 448.38. | |
| Orientin-2''-O-p-trans-coumarate | Orientin-2''-O-p-trans-coumarate is a compound of the flavonoid class found in the herbs of Swertia mileensis. Synonyms: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]-; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]-4H-1-benzopyran-4-one; Luteolin 8-C-(2''-O-(E)-p-coumaroyl-β-glucopyranoside); Orientin 2''-O-p-trans-coumarate; (1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-2-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-D-glucitol. Grades: >98%. CAS No. 1229437-75-5. Molecular formula: C30H26O13. Mole weight: 594.52. | |
| Orotidine | Orotidine is a nucleoside metabolized from orotic acid. In humans, orotidine occurs as its 5'-phosphate (orotidylic acid), which is an intermediate in pyrimidine nucleotide biosynthesis (cytidine and uridine) that are found in nucleic acids. Synonyms: 6-Carboxyuridine; 3-Ribofuranosylorotic acid; Uridin-6-carboxylic acid. CAS No. 314-50-1. Molecular formula: C10H12N2O8. Mole weight: 288.21. | |
| Oroxin A | Oroxin A is a flavonoid glycoside isolated from the herb Oroxylum indicum (L.) Kurz. It exhibits antioxidant property. Synonyms: 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-; 7-(β-D-Glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one; 5,6,7-Trihydroxyflavone 7-O-β-D-glucopyranoside; Baicalein 7-O-glucopyranoside; Baicalein 7-O-β-D-glucopyranoside; Baicalein 7-O-β-D-glucoside; Baicalein-7-O-glucoside; Baikalin; Biacalein 7-O-glucoside; Deglucosyloroxin B. Grades: >98%. CAS No. 57396-78-8. Molecular formula: C21H20O10. Mole weight: 432.38. | |
| Orphanin FQ (1-11) | Orphanin FQ is a NOP agonist and it shows analgesic properties. Synonyms: H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-OH; L-phenylalanyl-glycyl-glycyl-L-phenylalanyl-L-threonyl-glycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanine; 1-11-Orphanin FQ (pig); 1-11-Orphanin FQ (swine); Nociceptin (1-11). Grades: ≥98% by HPLC. CAS No. 178249-41-7. Molecular formula: C49H75N15O14. Mole weight: 1098.20. | |
| Orphenadrine hydrochloride | A skeletal muscle relaxant used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. Uses: Orphenadrine is an anticholinergic with a predominantly central effect and only a weak peripheral effect. Synonyms: N, N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine; hydrochloride. Grades: > 98 %. CAS No. 341-69-5. Molecular formula: C18H23NO · HCl. Mole weight: 305.84. | |
| ortho-Hydroxy Atorvastatin Calcium Salt | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: 2-hydroxy Atorvastatin Calcium salt; Sodium (3R,5R)-7-(2-(4-fluorophenyl)-4-((2-hydroxyphenyl)carbamoyl)-5-isopropyl-3-phenyl-1Hp-pyrrol-1-yl)-3,5-dihydroxyheptanoate. Grades: > 95%. CAS No. 265989-46-6. Molecular formula: C66H68CaF2N4O12. Mole weight: 1187.36. | |
| Orvepitant | Orvepitant is a potent and selective Neurokinin-1 (NK1) antagonist. It may be potential therapeutic for the treatment of patients with major depressive disorder (MDD), anxiety and insomnia. It was developed by GlaxoSmithKline and is in clinical phase 2 trials. Uses: Orvepitant may be potential therapeutic for the treatment of patients with major depressive disorder (mdd), anxiety and insomnia. Synonyms: (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide;Orvepitant; GW-823296; GW823296; GW 823296; GW823296X. Grades: 95%. CAS No. 579475-18-6. Molecular formula: C31H35F7N4O2. Mole weight: 628.63. | |
| Orvepitant maleate | Orvepitant maleate is a neurokinin-1 (NK1) receptor antagonist developed for the treatment of depression and anxiety disease. Uses: Potential treatment of depression and anxiety disease. Synonyms: GW-823296B; GW823296B; GW 823296B; Orvepitant maleate; (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide (Z)-but-2-enedioic acid. Grades: 99%. CAS No. 579475-24-4. Molecular formula: C31H35F7N4O2.C4H4O4. Mole weight: 744.7. | |
| Osilodrostat | Osilodrostat, also called as LCI699, is a modulator of 11-β-hydroxylase (IC50 = 2.5 nM), useful for treating a disorder ameliorated 11-β-hydroxylase inhibition, and a potent inhibitor of aldosterone synthase (IC50 = 0.7 nM). Synonyms: 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile; LCI699. CAS No. 928134-65-0. Molecular formula: C13H10FN3. Mole weight: 227.24. | |
| OSMI-1 | OSMI-1 is an inhibitor of O-GlcNAc transferase (OGT) with IC50 value of 2.7 μM in vitro. It is cell-permeable and inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans. Synonyms: (2R)-N-(2-furylmethyl)-2-(2-methoxyphenyl)-2-{[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]amino}-N-(2-thienylmethyl)acetamide. Grades: ≥98%. CAS No. 1681056-61-0. Molecular formula: C28H25N3O6S2. Mole weight: 563.6. | |
| OSS-128167 | OSS-128167 is a selective SIRT6 inhibitor (IC50 = 89 μM). Synonyms: OSS-128167; OSS 128167; OSS128167; SIRT6-IN-1; STK292625; STK 292625; STK-292625; 5-[3-(furan-2-amido)benzamido]-2-hydroxybenzoic acid; 5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid. Grades: 99%. CAS No. 887686-02-4. Molecular formula: C19H14N2O6. Mole weight: 366.32. | |
| Osthenol | Osthenol is a hydroxycoumarin with antitumor-promoting, antifungal and antibacterial activity. Synonyms: 7-hydroxy-8-prenylcoumarin. Grades: 98%. CAS No. 484-14-0. Molecular formula: C14H14O3. Mole weight: 230.3. | |
| OSU 6162 hydrochloride | OSU 6162 hydrochloride is a dopamine stabilizer. It is highly active on dopamine synthesis and turnover. It can antagonize the expression of L-DOPA induced behavioral sensitization. Uses: Dopamine d2 receptor antagonists. Synonyms: (S)-3-(3-(Methylsulfonyl)phenyl)-1-propylpiperidine hydrochloride; Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, hydrochloride (1:1), (3S)-; PNU 96391; PNU96391; PNU-96391; Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, monohydrochloride, (3S)-; Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, hydrochloride, (S)-; (-)-OSU 61612; OSU 6162; OSU 6162 monohydrochloride. Grades: ≥98% by HPLC. CAS No. 156907-84-5. Molecular formula: C15H23NO2S.HCl. Mole weight: 317.87. | |
| O-Sulfonato-L-tyrosine sodium salt | O-Sulfonato-L-tyrosine sodium salt, an amino acid derivative utilized in biomedical research, presents itself as a valuable asset. Its application as a protein tyrosine phosphatase and kinase specificity substrate highlights its pertinence in the industry. Excitingly, it has been researched extensively for its anti-inflammatory attributes and could potentially offer new remedies for autoimmune diseases. Synonyms: H-Tyr(SO3H)-OH, sodium salt. Grades: 95%. CAS No. 98930-06-4. Molecular formula: C9H10NNaO6S. Mole weight: 283.24. | |
| OSW-1 | OSW-1 is a natural steroidal saponin from Ornithogalum Saundersiae bulbs. It exhibits anti-entervirus and anti-cancer activity. Synonyms: (3β,16β)-16-[[2-O-Acetyl-3-O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-α-L-arabinopyranosyl]oxy]-3,17-dihydroxycholest-5-en-22-one; Orsaponin. CAS No. 145075-81-6. Molecular formula: C47H68O15. Mole weight: 873.046. | |
| o-Toluenesulfonicacid | o-Toluenesulfonic acid functions as a vital catalyst and acidic promoter frequently applied in the synthesis of organic compounds. Such a component is especially prevalent in the pharmaceutical sector owing to its ability to yield antihistamines, antitumor agents, and antibiotics. This reagent is an indispensable tool in advancing new medicines and treatments for a range of medical conditions and ailments. Synonyms: 2-Toluenesulfonic acid; Toluene-2-sulfonic acid; Benzenesulfonic acid, 2-methyl-; Toluene sulfonic acid; Toluenesulphonic acid; o-methylbenzenesulfonic acid. Grades: 95%. CAS No. 88-20-0. Molecular formula: C7H8O3S. Mole weight: 172.20. | |
| OT-R antagonist 1 | OT-R antagonist 1 is a nonpeptide OT-R antagonist, inhibitis IP3-Synthesis, rat OT-R (IC50 = 8 nM). Uses: A new potent and selective nonpeptide ot-r antagonist. Synonyms: LS-192629; LS 192629; LS192629. (4Z)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl-4-biphenylyl)carbonyl]-L-prolinamide. Grades: ≥98%. CAS No. 364071-17-0. Molecular formula: C28H29N3O4. Mole weight: 471.54. | |
| OT-R antagonist 2 | OT-R antagonist 2 is a nonpeptide OT-R antagonist, inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM). Uses: A nonpeptide low molecular weight ot-r antagonist. Synonyms: (4E)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl-4-biphenylyl)carbonyl]-L-prolinamide. Grades: ≥98%. CAS No. 364071-16-9. Molecular formula: C28H29N3O4. Mole weight: 471.54. | |
| OTS-514 | OTS-514, a quinolone derivative, is an effective TOPK inhibitor and has been found to have potential effect against Renal cancer. It is still under preclinical trials. IC50: 2.6 nM. Uses: Ots-514 is an effective topk inhibitor and has been found to have potential effect against renal cancer. Synonyms: OTS514; OTS 514; OTS-514. Grades: 98%. CAS No. 1338540-63-8. Molecular formula: C21H20N2O2S. Mole weight: 364.46. | |
| OTS964 | OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK) with IC50 value of 28 nM. OTS964 targets glioma stem cells (GSCs) and inhibits their growth, resulting in shrinkage of the power-law coded GSC populations. Synonyms: OTS-964; OTS 964; 9-[4-[(2R)-1-(dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methyl-5H-thieno[2,3-c]quinolin-4-one. Grades: ≥98%. CAS No. 1338542-14-5. Molecular formula: C23H24N2O2S. Mole weight: 392.5. | |
| OTSSP167 | OTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK-expressing tumor cells. MELK, a serine/threonine kinase, is involved in cancer cell survival, invasiveness and cancer-stem cell formation and maintenance; it is highly upregulated in various types of cancer cells and absent in normal, healthy cells. Synonyms: 1- (6- (3, 5-dichloro-4-hydroxyphenyl) -4- ( ( (1r, 4r) -4- ( (dimethylamino) methyl) cyclohexyl) amino) -1, 5-naphthyridin-3-yl) ethanone; OTSSP167 free base; OTSSP 167; OTSSP-167; OTS167; OTS-167; OTS 167. Grades: 0.98. CAS No. 1431697-89-0. Molecular formula: C25H28Cl2N4O2. Mole weight: 487.425. | |
| OTX008 | OTX008, a calixarene derivative, is a galectin-1 (Gal-1) inhibitor with potential anti-angiogenic and antineoplastic activities. In vitro, OTX008 effects in a panel of human cancer cell lines. In vivo, an ovarian xenograft model was employed to analyse the antitumour activity. Synonyms: Acetamide, 2, 2', 2'', 2'''-[pentacyclo[19.3.1.13, 7.19, 13.115, 19]octacosa-1(25), 3, 5, 7(28), 9, 11, 13(27), 15, 17, 19(26), 21, 23-dodecaene-5, 11, 17, 23-tetrayltetrakis(oxy)]tetrakis[N-[2-(dimethylamino)ethyl]-.; OTX-008; OTX 008; OTX008; PTX008; PTX-008; PTX 008; calixarene 0118; N(2dimethylamino)ethyl)acetamidyl calix4arene. Grades: >98%. CAS No. 286936-40-1. Molecular formula: C52H72N8O8. Mole weight: 937.18. | |
| OU749 | OU749 is a non-competitive gamma-glutamyl transpeptidase (GGT) inhibitor. It inhibits GGT isolated from human kidney with 7-10-fold greater potency than GGT isolated from rat or mouse kidney. Synonyms: N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide. Grades: ≥95%. CAS No. 519170-13-9. Molecular formula: C16H15N3O3S2. Mole weight: 361.4. | |
| Oxaliplatin | Oxaliplatin is a platinum-based antineoplastic agent used in cancer chemotherapy that inhibits DNA synthesis by conforming DNA adducts in cancer cells. Synonyms: Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum; 1,2-Cyclohexanediamine, platinum complex, (1R-trans)-; Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1R-trans)]-; Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN,κN'][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-; Dacplat; Eloxatin; Elplat; l-OHP; Lipoxal; NSC 266046; Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II); Oxalato[trans-(-)-1,2-cyclohexanediamine]platinum(II); Oxalatoplatin; Oxalatoplatinum; Platinum, (1,2-cyclohexanediamine-κN,κN')[ethanedioato(2-)-κO1,κO2]-, [SP-4-2-(1R-trans)]-; RP 54780; trans-L-Diaminocyclohexane oxalatoplatinum. Grades: >98%. CAS No. 61825-94-3. Molecular formula: C8H14N2O4Pt. Mole weight: 397.29. | |
| Oxalosuccinic acid barium salt | The biomedical industry leverages Oxalosuccinic acid barium salt as a laboratory reagent to unravel anatomical irregularities pertaining to calcium deposits found in tissues. This multipurpose product has been regarded as an instrumental diagnostic tool, in particular, for detecting foreseeable diseases, including aortic stenosis and nephrolithiasis, thereby supporting the development of life-saving treatments. Synonyms: barium 2-(carboxymethyl)-3-oxosuccinate. CAS No. 58823-93-1. Molecular formula: C6H4BaO7. Mole weight: 325.42. | |
| Oxamniquine | Oxamniquine, with schistosomicidal activity, is an antischistosomal drug used in the treatment of Schistosoma mansoni infection. Synonyms: [7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl]methanol; Oxaminiquine; Oxamniquine; UK 4271; UK-4271; UK4271. Grades: >98%. CAS No. 21738-42-1. Molecular formula: C14H21N3O3. Mole weight: 279.34. | |
| Oxetane-3-carboxylic acid | Synonyms: 3-Oxetanecarboxylic acid. Grades: 95 %. CAS No. 114012-41-8. Molecular formula: C4H6O3. Mole weight: 102.09. | |
| OXi-4503 | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. In addition, orthoquinone intermediates, metabolized from combretastatin A1 by oxidative enzymes found to be elevated levels in some tumor types, may bind to tumor cell thiol-specific antioxidant proteins and DNA, and stimulate oxidative stress by enhancing superoxide/hydrogen peroxide production. CA1 binds to tubulin at the same site as colchicine but with higher affinity. Synonyms: OXi4503; OXi 4503; CA1P; tetrasodium [3-methoxy-2-phosphonatooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate. Grades: >98%. CAS No. 288847-35-8. Molecular formula: C18H22O12P2. Mole weight: 492.31. | |
| oxiran-2-ylmethyl 2-ethyl-2,5-dimethylhexanoate | Oxiran-2-ylmethyl 2-ethyl-2,5-dimethylhexanoate, a chemical compound with potential pharmaceutical applications, requires further research to fully understand its medical potential. Synonyms: 2,3-Epoxypropyl neodecanoate; Glycidyl ester of versatic acid; Glycidyl neodecanoate. CAS No. 26761-45-5. Molecular formula: C13H24O3. Mole weight: 228.33. | |
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