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Ellagic acid
Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits. It has been fraudulently marketed as having the ability to prevent and treat a number of human maladies, including cancer, but such claims have not been proven. Ellagic acid can be used in cosmetics material. Uses: Anti-proliferative; anti-oxidant. Alternative Names: Elagostasine, Gallogen; Alizarine Yellow; Benzoaric acid; CCRIS 774; CCRIS774; CCRIS-774; HSDB 7574; HSDB7574; HSDB-7574; Lagistase. Grades: >98%. CAS No. 476-66-4. Molecular formula: C14H6O8. Mole weight: 302.19.
Ellagic acid-[13C12]
Ellagic acid-[13C12] is the labelled analogue of Ellagic acid. Ellagic acid is a natural phenol antioxidant found in numerous fruits and vegetables. The antiproliferative and antioxidant properties of ellagic acid have prompted research into its potential health benefits. Ellagic acid can be used in cosmetics material. Alternative Names: [13C12]-Ellagic acid. Molecular formula: C2[13C]12H6O8. Mole weight: 314.11.
Emamectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4''-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Alternative Names: L 656748; (4''R)-5-O-Demethyl-4''-deoxy-4''-(methylamino)avermectin A1a; 4''-Deoxy-4''-epi-(methylamino)avermectin B1a. Grades: >99% by HPLC. CAS No. 121124-29-6. Molecular formula: C49H75NO13. Mole weight: 886.12.
Emamectin B1b
It is a semi-synthetic 4-epimethylamino analogue of avermectin B1b. It is prepared by oxidation of the 4-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Alternative Names: Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-4''-(methylamino)-25-(1-methylethyl)-, (4''R)-. Grades: >99% by HPLC. CAS No. 121424-52-0. Molecular formula: C48H73NO13. Mole weight: 872.09.
Emericid
It is produced by the strain of Streptomyces hygroscppicus DS 24 367. It has anti-gram-positive bacterial activity and can be used to treat coccidiosis of poultry. Alternative Names: lonomycin; Antibiotic DE-3936; Lonomycin A; Antibiotic TM 481; (S)-2-((2R,3R,4S,5R,6S)-2-hydroxy-6-((S)-1-((2S,5R,7S,8R,9S)-2-((2S,2'R,3'S,4'R,5R,5'R)-5'-((2S,3S,4S,5R,6S)-6-hydroxy-4-methoxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-4'-methoxy-2,3'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-9-methoxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)ethyl)-4-methoxy-3,5-dimethyltetrahydro-2H-pyran-2-yl)propanoic acid. CAS No. 58785-63-0. Molecular formula: C44H76O14. Mole weight: 829.07.
Emodepside
Emodepside, also known as PF 1022-221, a semisynthetic derivative of PF1022A, is efficacious against a variety of gastrointestinal nematodes and used as an anthelmintic drug with broad-spectrum anthelmintic activity. Emodepside is an octapeptide drug that has been approved for use in cats. Alternative Names: BAY 44-4400; BAY44-4400; BAY-44-4400; BAY 444400; BAY444400; BAY-444400; cyclo[N(Me)Leu-D-OAla-N(Me)Leu-D-OPhe(morpholino)-N(Me)Leu-D-OAla-N(Me)Leu-D-OPhe(morpholino)]; cyclo[N-methyl-L-leucyl-N-oxa-D-alanyl-N-methyl-L-leucyl-N-oxa-4-morpholino-D-phenylalanyl-N-methyl-L-leucyl-N-oxa-D-alanyl-N-methyl-L-leucyl-N-oxa-4-morpholino-D-phenylalanyl]. Grades: ≥95%. CAS No. 155030-63-0. Molecular formula: C60H90N6O14. Mole weight: 1119.39.
Emodin
Emodin is an anthraquinone found naturally in the roots and barks of numerous plants. It exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. It has anti-cancer, anti-depressant and anti-microbial effects. Alternative Names: Emodol; Frangula emodin; HSDB 7093; NSC 408120; NSC 622947; 3-methyl-1,6,8-trihydroxyanthraquinone; 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione; 1,6,8-Trihydroxy-3-methylanthraquinone; 4,5,7-Trihydroxy-2-methylanthraquinone; Archin; Frangulic Acid; Rheum Emodin; Schuttgelb. Grades: 95%. CAS No. 518-82-1. Molecular formula: C15H10O5. Mole weight: 270.24.
Empagliflozin
Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Alternative Names: BI10773; BI-10773; BI 10773; CE0108; CS0940; PB23119; VA10802; AJ93046; Empagliflozin; trade name Jardiance. Grades: >98%. CAS No. 864070-44-0. Molecular formula: C23H27ClO7. Mole weight: 450.91.
Emtricitabine
Emtricitabine moderately reduces hepatocyte proliferation independent of effects on mtDNA in HepG2 human hepatoma cells. Alternative Names: Emtricitabine; Coviracil; Emtriva; Racivir; (-)-FTC; W-201247; W-201248; E1007; 24229-EP2298783A1; 24229-EP2314590A1; AB01275429-01; 3B2-0188. Grades: >98%. CAS No. 143491-57-0. Molecular formula: C8H10FN3O3S. Mole weight: 247.25.
endo-BCN-PEG4-PFP ester
endo-BCN-PEG4-PFP ester. Alternative Names: perfluorophenyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate. Grades: ≥98%. CAS No. 1421932-52-6. Molecular formula: C28H34F5NO8. Mole weight: 607.57.
Endomorphin 2
Endomorphin 2, an andogenous peptide, has high affinity and specificity for the μ-opioid receptor and displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Uses: Analgesics, opioid. Alternative Names: H-Tyr-Pro-Phe-Phe-NH2; L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide; (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide. Grades: >95%. CAS No. 141801-26-5. Molecular formula: C32H37N5O5. Mole weight: 571.7.
Endothelin 1 (swine, human)
Endothelin 1 (swine, human), a vasoconstrictor increased in plasma and explants of patients with uterine leiomyomas, is a synthetic peptide with the sequence of human and swine Endothelin 1 and acts through two types of receptors ETA and ETB. Alternative Names: Endothelin 1 swine, human; Endothelin 1; L-cysteinyl-L-seryl-L-cysteinyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide); H-Cys(1)-Ser-Cys(2)-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys(2)-Val-Tyr-Phe-Cys(1)-His-Leu-Asp-Ile-Ile-Trp-OH. Grades: 95%. CAS No. 117399-94-7. Molecular formula: C109H159N25O32S5. Mole weight: 2491.9.
Endotrophin (mouse)
Endotrophin, a carboxy-terminal cleavage product of the collagen 6α-3 chain produced and released by adipocytes, is greatly upregulated in malignant tumors of the breast, liver colon and pancreas. Endotrophin provides a link between obesity and aggressive tumor growth and may serve as a sensitive diagnostic marker and effective therapeutic target for designing better treatments for cancer and improving obesity-induced insulin resistance. Alternative Names: H-Thr-Glu-Pro-Leu-Phe-Leu-Thr-Lys-Thr-Asp-Ile-Cys-Lys-Leu-Ser-Arg-Asp-Ala-Gly-Thr-Cys-Val-Asp-Phe-Lys-Leu-Leu-Trp-His-Tyr-Asp-Leu-Glu-Ser-Lys-Ser-Cys-Lys-Arg-Phe-Trp-Tyr-Gly-Gly-Cys-Gly-Gly-Asn-Glu-Asn-Arg-Phe-His-Ser-Gln-Glu-Glu-Cys-Glu-Lys-Met-Cys-Ser-Pro-Glu-Leu-Thr-Val-OH (Disulfide bridge: Cys12-Cys62, Cys21-Cys45, Cys37-Cys58, air oxidized). Grades: ≥95%. CAS No. 1678414-54-4. Molecular formula: C345H520N92O106S7. Mole weight: 7876.94.
Enduracidin A
It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Alternative Names: 1-Oxa-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46-pentadecaazacyclononatetracontane, enduracidin A derivative; [1(Z,E),10(R),15(R)]-N-(10-Methyl-1-oxo-2,4-undecadienyl)-L-α-aspartyl-L-threonyl-D-2-(4-hydroxyphenyl)glycyl-D-ornithyl-D-allothreonyl-L-2-(4-hydroxyphenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-L-allothreonyl-N5-(aminocarbonyl)-L-ornithyl-3-(2-amino-4,5-dihydro-1H-imidazol-4-yl)-D-alanyl-L-2-(4-hydroxyphenyl)glycyl-D-seryl-L-2-(3,5-dichloro-4-hydroxyphenyl)glycylglycyl-3-(2-amino-4,5-dihydro-1H-imidazol-4-yl)-L-alanyl-D-alanyl-L-2-(4-hydroxyphenyl)glycine 1-lactone; Enramycin A. Grades: >95%. CAS No. 34438-27-2. Molecular formula: C107H138Cl2N26O31. Mole weight: 2355.30.
Enduracidin B
It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Alternative Names: Enramycin B. Grades: 85%. CAS No. 34304-21-7. Molecular formula: C108H140Cl2N26O31. Mole weight: 2369.32.
Enfortumab vedotin-ejfv
Enfortumab vedotin-ejfv is a first-in-class monoclonal antibody drug conjugate that binds Nectin-4, a protein expressed on bladder cancer cells, and delivers the tubulin toxin, monomethyl auristatin E, into the cell causing cell death. Enfortumab vedotin-ejfv was approved by FDA for the treatment of locally advanced or metastatic urothelial cancer. Alternative Names: Padcev. CAS No. 1346452-25-2.
Enfumafungin
Enfumafungin is a triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. Enfumafungin is an antifungal agent that acts on fungal cell walls as an inhibitor of (1,3)-beta-D-glucan synthase. It is specific for yeast and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis. Alternative Names: 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 14-(acetyloxy)-8-[(1R)-1,2-dimethylpropyl]-15-(β-D-glucopyranosyloxy)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-4-hydroxy-1,6a,8,10a-tetramethyl-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aS,14R,15R)-. Grades: ≥98%. CAS No. 260979-95-1. Molecular formula: C38H60O12. Mole weight: 708.88.
Enniatin A
It is produced by the strain of Fusarium orthoceras var. enniatinum. It has insecticidal and antifungal activity. Alternative Names: Cyclo((2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl); N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-); Lateritin I. Grades: >99% by HPLC. CAS No. 2503-13-1. Molecular formula: C36H63N3O9. Mole weight: 681.90.
Enniatin A1
A family of depsipeptide ionophores, produced by several fusarium species. It has antibiotic properties. Enniatin A1 is one of four major analogues in the enniatin complex. Enniatin A1 has been found to induce apoptosis in cancer cells, decrease the activation of the cell proliferation kinase, ERK (p44/p42) and inhibit TNF-α-induced NF-κB activation. Alternative Names: 2-(N-Methyl-L-valine)enniatin A; Cyclo(D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-valyl); cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl]; Cyclo((2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl). Grades: >99% by HPLC. CAS No. 4530-21-6. Molecular formula: C35H61N3O9. Mole weight: 667.87.
Enrofloxacin
Enrofloxacin is a fluoroquinolone antibiotic that prevents DNA superhelix and DNA synthesis by inhibiting bacterial DNA gyrase (a type II topoisomerase). It can be used for bacterial diseases caused by sensitive bacteria in livestock and small animals. Alternative Names: Baytril; Enrofloxacine; CFPQ; Enrofloxacino; Bay Vp 2674. Grades: >98%. CAS No. 93106-60-6. Molecular formula: C19H22FN3O3. Mole weight: 359.39.
ent-Abacavir
ent-Abacavir (Abacavir EP Impurity A) is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Uses: Anti-hiv agents. Alternative Names: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A. Grades: 97%. CAS No. 136470-79-6. Molecular formula: C14H18N6O. Mole weight: 286.33.
Entecavir monohydrate
Entecavir triphosphate is a highly potent inhibitor of wild-type HBV Pol and is 100- to 300-fold more potent than lamivudine triphosphate against 3TC-resistant HBV Pol. It competes with dGTP to be incorporated into viral DNA. Uses: Antiviral agents. Alternative Names: Entecavir (monohydrate); UNII-5968Y6H45M; 5968Y6H45M. Grades: 98%. CAS No. 209216-23-9. Molecular formula: C12H15N5O3.H2O. Mole weight: 295.29.
Enterobactin
It is produced by the strain of Escherichia coli, Salmonella typhi LT2. Enterobactin is a phenolic iron separation reagent and can be used as a growth accelerator. Alternative Names: Enterochelin; tri-(2,3-dihydroxy-N-benzoyl-L-serine)-ester; tri-(N-(2,3-dihydroxybenzoyl)-L-serine)-ester; Enterochellin; N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide); Benzamide, N,N',N''-(2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl)tris[2,3-dihydroxy-, [3S-(3R*,7R*,11R*)]-. CAS No. 28384-96-5. Molecular formula: C30H27N3O15. Mole weight: 669.55.
Enteromycin
It is produced by the strain of Streptomyces albireticuli. It has anti-gram positive bacteria and negative bacteria activity. Alternative Names: Enteromycine; Seligocidin; N-(O-Methyl-aci-nitroacetyl)-3-aminoacrylic acid; Acrylic acid, 3-(2-(methyl-aci-nitro)acetamido)-, (E)-; (E)-3-[[(Methyl-aci-nitro)acetyl]amino]propenoic acid. CAS No. 3552-16-7. Molecular formula: C6H8N2O5. Mole weight: 188.14.
Enzalutamide-[d6]
Enzalutamide-[d6] is a deuterium labelled form of Enzalutamide. Enzalutamide is a nonsteroidal antiandrogen medication which is used in the treatment of prostate cancer. Alternative Names: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide-d6; Enzalutamide D6. Grades: >98%. CAS No. 1443331-94-9. Molecular formula: C21H10D6F4N4O2S. Mole weight: 470.47.
(+)-EPIBATIDINE
(+)-EPIBATIDINE. Alternative Names: (+)-EPIBATIDINE HYDROCHLORIDE \ POTENT N ICOTINIC RECEPTOR AGONIST; CMI 488, exo-(+)-1R,2R,4S-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane hydrochloride, exo-(+)-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane hydrochloride. Grades: 95%. CAS No. 152885-09-1. Molecular formula: C11H13ClN2HCl.
(-)-Epibatidine dihydrochloride
(-)-Epibatidine dihydrochloride is a highly potent nicotinic agonist and (-)-Enantiomer of (±)-Epibatidine dihydrochloride. Alternative Names: (3S)-3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grades: 99%. CAS No. 152378-30-8. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61.
(+)-Epibatidine dihydrochloride
(+)-Epibatidine dihydrochloride is a highly potent nicotinic agonist and (+)-Enantiomer of (±)-Epibatidine dihydrochloride. Alternative Names: 3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grades: 99%. CAS No. 166374-43-2. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61.
(±)-Epibatidine dihydrochloride
(±)-Epibatidine dihydrochloride is a highly potent nicotinic agonist used as a non-narcotic analgesic. Uses: Analgesic. Alternative Names: (1R,3S,4S)-3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane dihydrochloride. Grades: 99%. CAS No. 162885-01-0. Molecular formula: C11H13ClN2.2HCl. Mole weight: 281.61.
Epicatechin
(-)-Epicatechin is a 2R,3R stereoisomer of catechin and is a naturally occurring flavanol. It is a powerful antioxidant and could inhibit cyclooxygenase. L-Epicatechin is a natural compound found in the woods of Acacia catechu (L.F.) Willd, it can be used in cosmetics material. Uses: Anti-oxidant; anti-atherogenic. Alternative Names: Epicatechin; (-)-Epicatechin; epi-Catechin; epi-Catechol; NSC 81161; NSC-81161; NSC81161. Grades: 95%. CAS No. 490-46-0. Molecular formula: C15H14O6. Mole weight: 290.27.
(+)-Epicatechin
(+)-Epicatechin is an antioxidant. Alternative Names: (2S,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; Dexepicatechin; ent-Epicatechin; (2S,3S)-2-(3,4-dihydroxyphenyl)chroman-3,5,7-triol; (+)-epicatechol; (2S,3S)-epicatechin; (+)-3,3',4',5,7-Pentahydroxyflavan. Grades: ≥97%. CAS No. 35323-91-2. Molecular formula: C15H14O6. Mole weight: 290.27.
(-)-Epicatechin-2,3,4-[13C3]
(-)-Epicatechin-2,3,4-[13C3] is the labelled analogue of (-)-Epicatechin. (-)-Epicatechin is a stereoisomer of catechin and is a naturally occurring flavanol. It is a powerful antioxidant and could inhibit cyclooxygenase. Alternative Names: (-)-Epicatechin-2,3,4-13C3; (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol-13C3; epi-Catechin-13C3; epi-Catechol-13C3; L-Acacatechin-13C3; L-Epicatechin-13C3; L-Epicatechol-13C3. Grades: ≥98%. Molecular formula: C12[13C]3H14O6. Mole weight: 293.25.
(-)-Epicatechin gallate
(-)-Epicatechin gallate (ECG) is a natural catechin with a single galloyl group. Like EGCG, it inhibits the growth of cancer cells and has anti-inflammatory effects. The hydroxyl groups of ECG contribute to its potent antioxidant activity and facilitate the killing of methicillin-resistant strains of S. aureus. (-)-Epicatechin gallate is a natural compound found in the woods of Acacia catechu (L.F.) Willd. It can be used in cosmetics material. Alternative Names: (-)-Epicatechin gallate;1257-08-5;Epicatechin gallate;(-)-epicatechingallate;(-)-Epicatechin-3-O-gallate;L-Epicatechin gallate;epicatechin monogallate;(-)-Epicatechin-3-gallate;Teatannin;Epicatechol, gallate;ECG;3-O-Galloylepicatechin;(-)-Epicatechin 3-O-gallate;epicatechin-3-O-gallate;(-)-cis-3,3',4',5,7-Pentahydroxyflavane 3-gallate;3-Gallate(-)-Epicatechol;CHEMBL36327;[(2R,3R)-2-(3,4-dihydroxyp. Grades: >98%. CAS No. 1257-08-5. Molecular formula: C22H18O10. Mole weight: 442.37.
Epidermin
Epidermin is a type A lantibiotic that is a tetracyclic 21-amino-acid peptide which contains meso-lanthionine, 3-methyllanthionine, and S-(2-aminovinyl)-D-cysteine. It is obtained from Staphylococcus epidermidis Tue 3298 and exhibits antibiotic activity against many Gram-positive bacteria. It has a role as a metabolite and an antibacterial agent. Alternative Names: Staphylococcin 1580. CAS No. 99165-17-0. Molecular formula: C98H141N25O23S4. Mole weight: 2165.58.
Epigallocatechin
(-)-Epigallocatechin (EGC) is a natural flavonoid isolated from herbs of Berchemia kulingensis Schneid, and it has prominent antiplatelet activity and blood anticoagulation in a dose-dependent manner. (-)-Epigallocatechin is a natural compound, it can also be used in cosmetics material. Alternative Names: Epigallocatechin; Epigallocatechol; (2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol. Grades: >98%. CAS No. 970-74-1. Molecular formula: C15H14O7. Mole weight: 306.3.
Epigallocatechin gallate
EGCG is an antioxidant extracted from green tea, reduces Aβ42-induced cell death in three different cell types and inhibits β-secretase (IC50 = 1.6 μM). (-)-Epigallocatechin gallate is a natural compound found in the woods of Acacia catechu (L.F.) Willd. It can be used in cosmetic material. Alternative Names: EGCG cpd; epigallo-catechin gallate; epigallocatechin gallate; epigallocatechin-3-gallate; epigallocatechin-3-O-gallate; EGCG. Grades: >98%. CAS No. 989-51-5. Molecular formula: C22H18O11. Mole weight: 458.37.
epi-Ivermectin B1a
Epi-Ivermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 4.0 and 0.038 ppm, respectively). Alternative Names: 5-O-demethyl-22,23-dihydro-avermectin A1a; 2-dehydro-4-dihydro Avermectin B1a; epi-dihydro Avermectin B1a; 22,23-dihydro Avermectin B1a; 2-epi-Ivermectin B1a; 2-epi-Ivermectin H2B1a. Grades: >95% by HPLC. Molecular formula: C48H74O14. Mole weight: 875.09.
Epimedin C
Epmedin C, a natural product, has estrogen-like effects for ovariectomized mice. It was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. Uses: Epmedin c has been found to have immunostimulatory and anticancer effect. Alternative Names: 3-[(6-Deoxy-2-O-(6-deoxy-a-L-mannoppyranosyl)-a-L-mannopyranosyl)oxy]-7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 110642-44-9. Molecular formula: C39H50O19. Mole weight: 822.80.
Epimedoside A
Epimedoside A isolated from the herbs of Epimedium brevicornum Maxim. Uses: Antioxidant activity. Alternative Names: 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-. Grades: 0.95. CAS No. 39012-04-9. Molecular formula: C32H38O15. Mole weight: 662.7.
Epirubicin Hydrochloride
Epirubicin HCl, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Uses: Antibiotics, antineoplastic. Alternative Names: epi-Doxorubicin HCl; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride; (8S-cis)-4'-Epidoxorubicin Hydrochloride; 4'-epi-Adriamycin Hydrochloride; Ellence; Epidoxorubicin Hydrochloride; Farmorubicin; Pharmorubicin; NSC-759195; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)-. Grades: >98%. CAS No. 56390-09-1. Molecular formula: C27H29NO11.HCl. Mole weight: 579.98.
Epitalon
Epitalon is a synthetic tetra-peptide used to regulate the cell cycle through up-regulation of telomerase activity showing anticancer and anti-tumor metastatic effect. Uses: Regulate the cell cycle through up-regulation of telomerase activity. Alternative Names: H-Ala-Glu-Asp-Gly-OH; (S)-4-((S)-2-aminopropanamido)-5-(((S)-3-carboxy-1-((carboxymethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid; BDM-E; Epitalon; L-Alanyl-L-α-glutamyl-L-α-aspartylglycine. Grades: ≥98%. CAS No. 307297-39-8. Molecular formula: C14H22N4O9. Mole weight: 390.35.
Epitetracycline hydrochloride
A degradation product of tetracycline formed by acid-catalysed isomerisation of the dimethylamino-group at C4. It is an antibiotic and a cell selection agent. It exhibits little antibacterial activity. Alternative Names: 4-Epitetracycline hydrochloride; (4R,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride; Quatrimycin Hydrochloride; [4R-(4α,4aβ,5aβ,6α,12aβ)]-4-(dimethylamino)-. 1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride; 4-Epi-tetracycline monohydrochloride. Grades: >95% by HPLC. CAS No. 23313-80-6. Molecular formula: C22H24N2O8.HCl. Mole weight: 480.90.
Eplerenone
Eplerenone is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure. Alternative Names: Eplerenone; CGP-30083; SC-66110; CGP 30083; SC 66110; CGP30083; SC66110; Inspra; Selara. Grades: >98%. CAS No. 107724-20-9. Molecular formula: C24H30O6. Mole weight: 414.49.
Eprinomectin
Eprinomectin is a semi-synthetic GABA signaling potentiator used to inhibit bacterial infections. It causes neuromuscular paralysis in microbes and parasites. Eprinomectin is an avermectin selected for development as a topical endectocide. Alternative Names: Eprinex; Ivomec Eprinex; MK 397; MK-397; MK397. Grades: >98%. CAS No. 123997-26-2. Molecular formula: C50H75NO14. Mole weight: 914.13.
Eprinomectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination. Members of the Avermectin / Milbemycin class exert their insecticidal / anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. Alternative Names: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a; Avermectin A1a, 4'-(acetylamino)-5-O-demethyl-4'-deoxy-, (4'R)-; Eprinomectin component B1a. Grades: >99% by HPLC. CAS No. 133305-88-1. Molecular formula: C50H75NO14. Mole weight: 914.13.
Eprinomectin B1b
It is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination followed by acetylation. It is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin. It is a potent insecticide and acaricide. Alternative Names: (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a; Eprinomectin component B1b. Grades:>99% by HPLC. CAS No. 133305-89-2. Molecular formula: C49H73NO14. Mole weight: 900.10.
(±)-Equol
(R,S)-Equol is a flavonoid. Racemic mixture. This is a metabolite that is produced in vivo from soy phytoestrogen daidzein from gut microflora. (R,S)-Equol inhibits 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced neoplastic cell transformation by targeting the MEK/ERK/p90RSK / activator protein-1 signalling pathway. (R,S)-Equol shows positive effects on the incidence of prostate cancer. Functions as a DHT blocker. Preferentially activates estrogen receptor β (ERβ). Uses: Phytoestrogens. Alternative Names: 3-(4-hydroxyphenyl)chroman-7-ol. Grades: ≥98%. CAS No. 94105-90-5. Molecular formula: C15H14O3. Mole weight: 242.3.
Eravacycline
Eravacycline, also known as TP-434, a novel antibiotic. Eravacycline showed potent broad-spectrum activity against 90% of the isolates (MIC90) in each panel at concentrations ranging from 0.008 to 2 μg/ml for all species panels except those of Pseudomonas aeruginosa and Burkholderia cenocepacia (MIC90 values of 32 μg/ml for both organisms). Alternative Names: TP-434; TP 434; TP434. Grades: 98%. CAS No. 1207283-85-9. Molecular formula: C27H31FN4O8. Mole weight: 558.56.
Ercalcidiol-[d3]
Ercalcidiol-[d3] is the labelled analogue of 25-Hydroxyvitamin D2, which is a metabolite of Vitamin D2. Alternative Names: 25-Hydroxyvitamin D2 (6,19,19-d3). CAS No. 1217467-39-4. Molecular formula: C28H41D3O2. Mole weight: 415.67.
Ergocalciferol-[d6]
Ergocalciferol-[d6] is the labelled analogue of Ergocalciferol, which is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Alternative Names: Ergocalciferol D6. Grades: 95% by HPLC; 98% atom D. CAS No. 1311259-89-8. Molecular formula: C28H38D6O. Mole weight: 402.69.
Ergocalciferol EP Impurity B
Ergosterol is a sterol and a biological precursor (a provitamin) to vitamin D2. Uses: Antitumor. Alternative Names: Ergosterol; Provitamin D2; Ergosta-5,7,22E-trien-3beta-ol; 5,7,22-Ergostatrien-3beta-ol; 3beta-Hydroxy-5,7,22-ergostatriene. Grades: >98%. CAS No. 57-87-4. Molecular formula: C28H44O. Mole weight: 396.65.
Ergosta-4,6,8(14),22-tetraen-3-one
Ergosta-4,6,8(14),22-tetraen-3-one, isolated from the fruit body of Polyporus umbellatus, prevents early renal injury in aristolochic acid-induced nephropathy rats. Besides, Ergosta-4,6,8(14),22-tetraen-3-one induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells. It would be useful for the further utilization of many medicinal fungi in cancer treatment. Alternative Names: Ergone. Grades: >98%. CAS No. 19254-69-4. Molecular formula: C28H40O. Mole weight: 392.6.
Ergosta-7,22-dien-3-one
Ergosta-7,22-dien-3-one is a natural steroid compound found in several plants. Alternative Names: 17-[(Z)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-1,2,4,5,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Grades: 95%. CAS No. 32507-77-0. Molecular formula: C28H44O. Mole weight: 396.65.
Erinacine A
Erinacine A, derived from the Lion's Mane mushroom (Hericium erinaceus), is a bioactive compound with demonstrated anticancer, antitumor, and neuroprotective properties. It induces cancer cell death through the generation of reactive oxygen species (ROS) and is believed to modulate signaling pathways involved in cancer cell apoptosis. Additionally, Erinacine A exhibits neuroprotective effects against neurodegenerative diseases such as Parkinson's and Alzheimer's, potentially mitigating related pathological symptoms. Alternative Names: Cyclohept[e]indene-8-carboxaldehyde, 2,3,3a,4,5,5a,6,7-octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)-, (3aR,5aR,6S)-; (3aR,5aR,6S)-2,3,3a,4,5,5a,6,7-Octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)cyclohept[e]indene-8-carboxaldehyde; Cyclohept[e]indene-8-carboxaldehyde, 2,3,3a,4,5,5a,6,7-octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)-, [3aR-(3aα,5aβ,6α)]-; (+)-Erinacin A; Erinacin A; (3aR,5aR,6S)-3a,5a-Dimethyl-1-(propan-2-yl)-6-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2H,3H,3aH,4H,5H,5aH,6H,7H-cyclohepta[e]indene-8-carbaldehyde; (3aR,5aR,6S)-8-Formyl-1-isopropyl-3a,5a-dimethyl-2,3,3a,4,5,5a,6,7-octahydrocyclohepta[e]inden-6-yl β-D-xylopyranoside. Grades: ≥95% by HPLC. CAS No. 156101-08-5. Molecular formula: C25H36O6. Mole weight: 432.55.
Erinacine C
Erinacine C is a bioactive compound derived from the Hericium erinaceus mushroom, known for its potential neuroprotective properties. It is a cyathane diterpenoid with a unique chemical structure that has been studied for its ability to stimulate the synthesis of nerve growth factor (NGF), which can be beneficial in treating nervous system diseases such as Alzheimer's. Alternative Names: β-D-Xylopyranose, 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-; 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-Decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-β-D-xylopyranose; β-D-Xylopyranose, 1,2-O-[2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-, [3aR-(3aα,5aβ,6α,7β,10aα)]-; Erinacin C. Grades: ≥95% by HPLC. CAS No. 156101-09-6. Molecular formula: C25H38O6. Mole weight: 434.57.
Eriodictyol
Eriodictyol is a natural flavonoid found in the fruits of Citrus sinensis (L.) Osbeck. Eriodictyol exhibits activities of antidiabetic, anti-inflammatory and antioxidant. Eriodictyol can increases glucose uptake and improves insulin resistance. Alternative Names: (S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one; 3',4',5,7-tetrahydroxyflavanone; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-. Grades: >97%. CAS No. 552-58-9. Molecular formula: C15H12O6. Mole weight: 288.25.
Eriodictyol 7-O-glucoside
Eriodictyol 7-O-glucoside is isolated from the herbs of Dracocephalum rupestre. It has protective effect on cisplatin-induced toxicity. Alternative Names: (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one; eriodictyol-7-glucoside. Grades: 95%. CAS No. 38965-51-4. Molecular formula: C21H22O11. Mole weight: 450.39.
Erlotinib
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib has been indicated for non-small cell lung cancer (NSCLC) and pancreatic cancer therapy. Alternative Names: CP358774; CP 358774; CP-358774; NSC 718781; NSC718781; NSC-718781. Grades: >98%. CAS No. 183321-74-6. Molecular formula: C22H23N3O4. Mole weight: 393.44.
Erlotinib hydrochloride
Erlotinib HCl potently inhibits EGFR activation in intact cells including HNS human head and neck tumor cells (IC50 = 20 nM), DiFi humancolon cancer cells and MDA MB-468 human breast cancer cells. Uses: Antineoplastic agents. Alternative Names: OSI-744; OSI744; OSI 744; Tarceva; 4-(m-Ethynylanilino)-6,7-bis(2-methoxyethoxy)quinazoline monohydrochloride; 6,7-bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride. Grades: >98%. CAS No. 183319-69-9. Molecular formula: C22H23N3O4.HCl. Mole weight: 429.90.
Ertapenem
Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections. Alternative Names: (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-carboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl-4-methyl-7-oxo-, (4R,5S,6S)-; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-(((3-carboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, (4R-(3(3S*,5S*),4α,5β,6β(R*)))-. Grades: 95%. CAS No. 153832-46-3. Molecular formula: C22H25N3O7S. Mole weight: 475.52.
Ertapenem Sodium
Ertapenem Sodium is the sodium salt of ertapenem. Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections. Alternative Names: Invanz; Ertapenem sodium salt; MK-0826. Grades: 95% by HPLC. CAS No. 153773-82-1. Molecular formula: C22H24N3NaO7S. Mole weight: 497.50.
Erythritol-[13C4]
Isotope Labelled analogue of Erythritol, a sugar alcohol used as a food additive. Alternative Names: Erythritol-13C4; [UL-13C4]erythritol; rel-(2R,3S)-1,2,3,4-Butanetetrol-1,2,3,4-13C4. Grades: 98% by CP; 99% atom 13C. CAS No. 2230887-16-6. Molecular formula: [13C]4H10O4. Mole weight: 126.09.
erythro-1-(4-Hydroxyphenyl)propane-1,2,3-triol
Erythro-1-(4-Hydroxyphenyl)propane-1,2,3-triol is a potent natural compound exhibiting remarkable effectiveness in studying diverse ailments such as diabetes, obesity and cardiovascular disorders. Grades: 98%. CAS No. 25743-67-3. Molecular formula: C9H12O4. Mole weight: 184.19.
Erythromycin-[13C,d3] is the labelled analogue of Erythromycin, which is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. Alternative Names: Erythromycin-(N-methyl-13C,d3); E-Base-13C,d3; E-Mycin-13C,d3; Erytromycin A-13C,d3; Aknemycin-13C,d3; Aknin-13C,d3; Eemgel-13C,d3; Ery-Derm-13C,d3; Erymax-13C,d3; Ery-Tab-13C,d3; Erythromid-13C,d3; ERYC-13C,d3; Erythromycin-13C,d3. Grades: 98% (CP); 99% atom 13C; 98% atom D. CAS No. 959119-26-7. Molecular formula: C36[13C]H64D3NO13. Mole weight: 737.94.
Erythromycin A
Erythromycin A is a group of 14-membered macrolide antibiotics produced by Streptomyces erythreus. Erythromycin A is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml). It has a good effect on fish whitehead and white mouth disease, gill rot disease and kidney disease. Erythromycin can be used as an alternative medicine for animals allergic to penicillin. Alternative Names: erythromycin; E-Mycin; Erythrocin. CAS No. 114-07-8. Molecular formula: C37H67NO13. Mole weight: 733.93.
Erythromycin C
A minor co-metabolite of erythromycin produced by saccharopolyspora erythreae. It exhibits a narrow spectrum of antibacterial activity, and it is much less active than erythromycin A and B. Alternative Names: 3''-O-Demethylerythromycin A; Erythromycin Impurity 6. Grades: >98% by HPLC. CAS No. 1675-02-1. Molecular formula: C36H65NO13. Mole weight: 719.90.
Erythromycin ethylsuccinate
Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis. Alternative Names: Pediamycin; EryPed; Wyamycin E; Erythromycin ethyl succinate; Erythromycin, 2'-(ethyl butanedioate); Erythroped; Erythromycin A Ethylsuccinate; (2S,3R,4S,6R)-4-(Dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl succinate; Erythromycin, mono(ethyl succinate) (ester); Succinic acid, ethyl ester, monoester with erythromycin; Anamycin; Arpimycin; Durapaediat; Monomycin; Paediathrocin; Refkas; Sigapedil. Grades: ≥98%. CAS No. 1264-62-6. Molecular formula: C43H75NO16. Mole weight: 862.05.
Escin is an exquisite arboreal extract used for studying vascular disorders and revered for its profound anti-inflammatory attributes. Alternative Names: Escigenin, 3-(4-O-β-D-glucopyranosyl-2-O-β-D-xylopyranosyl-β-D-glucopyranuronoside), 3-hydroxy-2-methylbutyrate, acetate; Aescin; Aescine; Aescusan; Ba 2672; Escusan; Eskuzan; Flebostasin Retard; Venocin; β-Escinic acid; Aesculus. Grades: ≥95%. CAS No. 6805-41-0.