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Aprepitant glucuronide
Aprepitant glucuronide is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C29H29F7N4O9. Mole weight: 710.55.
Aprepitant Impurity 1
A metabolite of Aprepitant. Synonyms: (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-morpholine. Grades: > 95%. CAS No. 327623-37-0. Molecular formula: C20H18F7NO2. HCl. Mole weight: 437.36.
Aprepitant Impurity 10 HCl
Aprepitant Impurity 10 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2R,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride; 1447693-83-5. CAS No. 1447693-83-5. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant Impurity 11 HCl
Aprepitant Impurity 11 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant Impurity 12 HCl
Aprepitant Impurity 12 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant Impurity 13
Aprepitant Impurity 13 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C29H25F7N4O3. Mole weight: 610.52.
Aprepitant Impurity 14
Aprepitant Impurity 14 is a derivative of Aprepitant, which is a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Des-(4-fluorophenyl) 3-(R)-(4'-Fluorobiphen-4-yl) Aprepitant. Molecular formula: C29H25F7N4O3. Mole weight: 610.52.
Aprepitant Impurity 15
Aprepitant Impurity 15 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C23H22F6N4O4. Mole weight: 532.43.
Aprepitant Impurity 16
Aprepitant Impurity 16 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 638990-20-2. Molecular formula: C22H24N2O5. Mole weight: 396.44.
Aprepitant Impurity 17
Aprepitant Impurity 17 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C21H19F6NO3. Mole weight: 447.37.
Aprepitant Impurity 18
Aprepitant Impurity 18 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C12H7F9O2. Mole weight: 354.17.
Aprepitant Impurity 19
Aprepitant Impurity 19 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3,7-Dimethyl-3-octanol. CAS No. 78-69-3. Molecular formula: C10H22O. Mole weight: 158.28.
Aprepitant Impurity 1 Enantiomer HCl
A metabolite of Aprepitant. Synonyms: (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl) phenyl]ethoxy]-3-(4-fluorophenyl)-Morpholin. Grades: > 95%. CAS No. 171482-05-6. Molecular formula: C20H18F7NO2. HCl. Mole weight: 437.36 36.46.
Aprepitant Impurity 1 HCl
Aprepitant Impurity 1 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant Impurity 2
Aprepitant Impurity 2 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C24H25F7N4O4. Mole weight: 566.47.
Aprepitant Impurity 4 HCl
Aprepitant Impurity 4 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 1333998-21-2. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant Impurity 5 HCl
Aprepitant Impurity 5 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 1333995-14-4. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant Impurity 7 HCl
Aprepitant Impurity 7 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride. CAS No. 874460-46-5. Molecular formula: C20H19F6NO2.HCl. Mole weight: 455.82.
Aprepitant Impurity 8 HCl
Aprepitant Impurity 8 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Fosaprepitant Morpholine Hydrochloride; (2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333998-27-8. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant impurity A
Aprepitant impurity A is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2. Mole weight: 527.47.
Aprepitant Impurity A Enantiomer
Aprepitant Impurity A Enantiomer is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2. Mole weight: 527.47.
Aprepitant Impurity B Enantiomer HCl
A metabolite of Aprepitant. Synonyms: (2R,3S)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grades: > 95%. CAS No. 183901-47-5. Molecular formula: C27H24F7NO2. HCl. Mole weight: 527.49 36.46.
Aprepitant Impurity B HCl
Aprepitant Impurity B HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2.HCl. Mole weight: 563.93.
Aprepitant-M3 Metabolite
Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grades: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
Aprindine
Aprindine is a Class 1b antiarrhythmic agent as a cardiac depressant used in arrhythmias. Uses: A cardiac depressant used in arrhythmias. Synonyms: N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine. Grades: ≥98%. CAS No. 37640-71-4. Molecular formula: C22H30N2. Mole weight: 322.48.
APS
APS is an active sulfate ester of 5'-AMP, which is used in pyrosequencing and bioluminescence applications. Synonyms: Adenosine- 5'- O- phosphosulfate, sodium salt. Grades: guaranteed purity ≥ 95% by HPLC, usual purity ≥ 98%. CAS No. 102029-95-8. Molecular formula: C10H14N5O10PS (free acid). Mole weight: 427.3 (free acid).
APS-2-79
APS-2-79 is a small molecule antagonist of MEK phosphorylation by RAF through direct binding of the KSR active site, and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2). Synonyms: 6,7-Dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine; APS-2-79; APS 2-79; APS2-79; APS-279; APS 279; APS279. CAS No. 2002381-25-9. Molecular formula: C23H21N3O3. Mole weight: 387.43.
APS-5
APS-5 is a chemiluminescent substrate based on 9, 10-dihydroacridine, which is mainly used for ELISA detection of alkaline phosphatase AP conjugated compounds and for the diagnosis of immune detection, such as tumor markers, infectious diseases, endocrine function, hormones, etc. Synonyms: Methanol, [(4-chlorophenyl)thio](10-methyl-9(10H)-acridinylidene)-, 1-(dihydrogen phosphate), disodium salt (1:2); Methanol, [(4-chlorophenyl)thio](10-methyl-9(10H)-acridinylidene)-, dihydrogen phosphate (ester), disodium salt; Lumigen APS 5; Sodium ((4-chlorophenyl)thio)(10-methylacridin-9(10H)-ylidene)methyl phosphate; [(4-chlorophenyl)thio](10-methyl-9(10H)-acridinylidene)methanol 1-(dihydrogen phosphate) disodium salt; [[(4-chlorophenyl)thio]-(10-methyl-9-acridinylidene)methyl] phosphate disodium salt. Grades: ≥99% by HPLC. CAS No. 193884-53-6. Molecular formula: C21H15ClNNa2O4PS. Mole weight: 489.82.
APY0201
APY0201, an effective IL-12/23 inhibitor, has been found to have potential use in the treatment of inflammation. IC50 = 5.2 nM. Synonyms: APY0201; APY-0201; APY 0201. Grades: 98%. CAS No. 1232221-74-7. Molecular formula: C23H23N7O. Mole weight: 413.48.
Aquastatin A is an adenosine triphosphatase inhibitor produced by Fusariumaquaeductuum. Synonyms: 4-{[4-(Hexopyranosyloxy)-2-hydroxy-6-pentadecylbenzoyl]oxy}-2-hydroxy-6-methylbenzoic acid. CAS No. 153821-50-2. Molecular formula: C36H52O12. Mole weight: 676.79.
Aquastatin B
Synonyms: Aquqstatin B. CAS No. 160219-85-2. Molecular formula: C30H42O7. Mole weight: 514.65.
Aquastatin C
Aquastatin C is a new glycoaromatic derivative originally isolated from Sporothrix sp. FN611. Synonyms: Aquqstatin C. CAS No. 1344044-32-1. Molecular formula: C29H48O9. Mole weight: 540.68.
Aquayamycin
Aquayamycin is a quinone antibiotic produced by Streptomyces misawanensis MA944-A5. Aquayamycin has weak antibacterial activity, prolongs the life of mice inoculated with Ehrlich ascites cancer, and inhibits tyrosine hydroxylase and monoamine oxidase. Synonyms: Urdamycinone A; 9-(2,6-Dideoxy-beta-D-arabino-hexopyranosyl)-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione (3R-(3alpha,4aalpha,12balpha))-. Grades: >98%. CAS No. 26055-63-0. Molecular formula: C25H26O10. Mole weight: 486.47.
AR03
AR03 is a specific inhibitor of apurinic/apyrimidinic (AP) endonuclease 1 (APE1). Synonyms: BMH-23; BMH 23; BMH23; AR03; AR 03; AR-03; 2,4,9-trimethylbenzo[b][1,8]naphthyridin-5-amine. Grades: 99%. CAS No. 510721-85-4. Molecular formula: C15H15N3. Mole weight: 237.3.
AR12456
AR12456 is a trapidil derivative. It could protect against serum hyperlipidemia in guinea pigs. It has a strong antilipidemic action in guinea pigs fed a cholesterol-rich diet. Uses: Ar12456 could protect against serum hyperlipidemia and has a strong antilipidemic action. Synonyms: AR 12456; AR-12456; AR12456; Ethanol,2-[[5-(diethylamino)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]hexylamino]-;AR-12456;2-[[5-(Diethylamino)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]-hexylamino]ethanol;2-[(4-Diethylamino-1,5,7,9-tetrazabicyclo[4.3.0]nona-2,4,6,8-tetraen-2 -yl)-hexyl-amino]ethanol. Grades: >98 %. CAS No. 100557-06-0. Molecular formula: C17H30N6O. Mole weight: 334.47.
AR12463
AR12456 is a trapidil derivative. It protects against serum hyperlipidemia in guinea pigs. It has a strong antilipidemic action in guinea pigs fed a cholesterol-rich diet. Uses: Ar12456 could protect against serum hyperlipidemia and has a strong antilipidemic action. Synonyms: AR 12463; AR-12463; AR12463; Ethanol,2-[pentyl[5-(1-piperidinyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino]-;2-[Pentyl-(5-piperidin-1-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino]ethanol;2-[N-Pentyl-N-[[5-piperidino[1,2,4]triazolo[1,5-a]pyrimidin]-7-yl]amino]ethanol. Grades: >98 %. CAS No. 100557-04-8. Molecular formula: C17H28N6O. Mole weight: 332.45.
AR-12 Hydrochloride
OSU 03012, a Phenanthren derivative, has been found to be a PDPK1 inhibitor that could probably be an effctive antitumor agent. It is still under Phase I trail for solid-tumour. IC50: 5 μM. Synonyms: OSU-03012; AR-12; AR 12; AR12; OSU 03012; OSU03012; PDK1 inhibitor AR-12; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide. Grades: 98%. CAS No. 1471979-81-3. Molecular formula: C26H19F3N4O. Mole weight: 460.46.
AR-23
AR-23 is a melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties. Synonyms: AR-23; AMMONIUM, (m-HYDROXYPHENYL)TRIMETHYL-, METHYLSULFATE, BENZYLCARBAMATE; Benzylcarbamic ester of 3-oxyphenyltrimethylammonium methylsulfate; 64051-16-7; Ammonium, (3-(N-benzylcarbamoyloxy)phenyl)trimethyl-, methylsulfate; Carbamic acid, N-benzyl-, 3-(trimethylammonio)phenyl ester, methylsulfate; DTXSID50214190; LS-18471; [3-(benzylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate; Benzenaminium, N,N,N-trimethyl-3-[[[(phenylmethyl)amino]carbonyl]oxy]-, methyl sulfate. CAS No. 64051-16-7. Molecular formula: C18H24N2O6S. Mole weight: 396.5.
AR 244555
AR 244555 is an inverse agonist of Mas G-protein signaling (IC50 values 186 and 348 nM in human and rat inositol phosphatase (IP) Gq coupling assays respectively). AR 244555 inhibited inositol 1,4,5-trisphosphate accumulation in AdMas-infected cells and attenuated the sarcomeric organization and cell enlargement observed in Mas overexpressing myocytes. AR 244555 caused an increase in coronary flow in rat hearts without causing arrhythmias, and provides protection from ischemia-reperfusion injury if administered either before ischemia or immediately before reperfusion. Synonyms: AR244555; AR 244555; AR-244555; (1'-but-3-enyl-5-chlorospiro[2H-indole-3,4'-piperidine]-1-yl)-(2,6-difluorophenyl)methanone. Grades: 99%. CAS No. 858350-62-6. Molecular formula: C23H23ClF2N2O. Mole weight: 416.89.
AR 420626
AR 420626 ,a FFA3 agonist, has been found to be expressed in adipose tissue, the gastrointestinal tract, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation. Synonyms: AR-420626; AR 420626; AR420626. N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide. Grades: ≥98% by HPLC. CAS No. 1798310-55-0. Molecular formula: C21H18Cl2N2O3. Mole weight: 417.29.
AR-7
AR-7, also known as Atypical retinoid 7, was developed as a highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RAR&alpha. AR-7 was suggested to be used at 5-20 μM final concentration in vitro and in cellular assays. Synonyms: 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine; AR 7; AR7; Atypical retinoid 7. CAS No. 80306-38-3. Molecular formula: C15H12ClNO. Mole weight: 257.71.
AR-A014418
AR-A014418 is an ATP-competitive inhibitor of glycogen synthase kinase 3β (GSK-3β), a serine/threonine protein kinase involved in multiple diseases including Alzheimer's disease and type 2 diabetes. Synonyms: SN 4521; SN4521; SN-4521; AR-A 014418; AR-A014418; AR-A-014418; AR-AO-14418; GSK-3beta Inhibitor VIII; 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea. Grades: ≥ 98%. CAS No. 487021-52-3. Molecular formula: C12H12N4O4S. Mole weight: 308.312.
ara-Adenosine-5'-monophosphate (ara-AMP)
ara-Adenosine-5'-monophosphate (ara-AMP) is an adenosine monophosphate analog with antiviral and possibly antineoplastic properties. It inhibits DNA polymerase and also acts as a chain terminator in DNA replication. Synonyms: Vidarabine monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 29984-33-6. Molecular formula: C10H14N5O7P (free acid). Mole weight: 347.22 (free acid).
ara-Adenosine-5'-triphosphate
ara-Adenosine-5'-triphosphate (ara-ATP) is an adenosine triphosphate analog with an antiviral property that inhibits cleavage and polyadenylation reactions by interacting with the ATP-binding site on poly(A) polymerase. Synonyms: Araadenosine-5'-Triphosphate; Vidarabine triphosphate; Ara-ATP. Grades: ≥ 95% by HPLC. CAS No. 3714-60-1. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
Arabenoic acid
Arabenoic acid, a natural product herbicide of fungal origin. Synonyms: 5-Hydroxy-3-methoxy-2-pentenoic acid; Verrucolone; 2-Pentenoic acid, 5-hydroxy-3-methoxy-, (E)-. CAS No. 136468-08-1. Molecular formula: C6H10O4. Mole weight: 146.14.
Arabinan
Arabinan is an intriguing biopolymer procured from plants including gum arabic and diverse fruits. It has profound immunomodulatory and anticancer attributes. Synonyms: Arabinan; 11078-27-6; YA46077. CAS No. 11078-27-6. Molecular formula: C48H80O34. Mole weight: 1201.1.
Arabinofuranosyl-2,6-diamino-purine
Arabinofuranosyl-2,6-diamino-purine, a potent antiviral agent, is indicated for the prevention and treatment of viral infections such as herpes simplex, varicella-zoster virus, and hepatitis B. This drug acts by impeding synthesis of viral DNA, effectively suppressing replication of the virus. Recommended for intravenous administration, Arabinofuranosyl-2,6-diamino-purine is particularly useful in immunocompromised patients, especially those suffering from HIV/AIDS, who are at greater risk of succumbing to viral infections. Synonyms: 2,6-diaminopurine arabinoside; 9-(β-D-Arabinofuranosyl)-2,6-diaminopurine. Grades: ≥ 99%. Molecular formula: C10H14N6O4. Mole weight: 282.25.
Arabinofuranosyl-6-benzylamino-purine
Arabinofuranosyl-6-benzylamino-purine is a highly antiviral compound, finding extensive applications in a wide range of ailments including leukemia and solid tumors. Thus, it standing as an invaluable compound for scientific investigations and the development of pharmaceutical interventions within the dynamic realm of compound. Synonyms: 6-Benzylaminopurine arabinoside; 9-(β-D-Arabinofuranosyl)-6-benzylaminopurine. Grades: ≥ 99%. Molecular formula: C17H19N5O4. Mole weight: 357.36.
Arabinofuranosylcytosine-5'-triphosphate (triethylammonium salt form)
The triethylammonium salt form of Ara-CTP. Ara-CTP is a nucleotide that can be used as an antimetabolic agent to inhibit the synthesis of DNA. Synonyms: Ara-CTP (triethylammonium salt form); Cytosine arabinoside triphosphate triethylammonium; Arabinosylcytosine triphosphate triethylammonium; Arabinofuranosylcytosine triphosphate triethylammonium; Cytosine arabinoside 5'-triphosphate triethylammonium; Arabinosylcytosine 5'-triphosphate triethylammonium. Grades: ≥ 90% by HPLC, Concentration ~ 12 mM. Molecular formula: C9H16N3O14P3.C6H15N. Mole weight: 483.159 (free acid).
Arabinofuranosyl-guanine (ara-G)
Arabinofuranosyl-guanine (ara-G) is an inhibitor of DNA synthesis used as an antimetabolic and antineoplastic agent. Synonyms: Arabinosylguanine; 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-9-(β-D-arabinofuranosyl)purine; 9-β-D-Arabinofuranosylguanine; Araguanosine; Guanine arabinoside; NSC 76352; ara-Guanosine. Grades: ≥98% by HPLC. CAS No. 38819-10-2. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Arabinofuranosyl-hypoxanthine (ara-HX)
Arabinofuranosyl-hypoxanthine (ara-HX) is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. Uses: Antiviral agents. Synonyms: Hypoxanthine arabinoside; 9-(β-D-Arabinofuranosyl)-hypoxanthine; 9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one; 9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one. Grades: ≥ 99%. CAS No. 7013-16-3. Molecular formula: C10H12N4O5. Mole weight: 268.22.
Arabinofuranosyl-isoguanine
Arabinofuranosyl-isoguanine is a nucleoside analog used as an antiviral drug to treat herpes simplex virus type 1 and 2 infections. It works by inhibiting viral DNA synthesis, thus preventing the virus from replicating and spreading. Synonyms: 9-(β-D-Arabinofuranosyl)-isoguanine. Grades: ≥ 98%. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Arabinoisocytidine
Arabinoisocytidine: A pioneering compound widely utilized in the biomedical sector due to its remarkable potential in combating diverse viral infections and cancers. With its role as a nucleoside analog, Arabinoisocytidine showcases commendable antiviral and antitumor properties by obstructing viral DNA replication and instigating apoptosis within malignant cells. Synonyms: 2-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one; 2'beta-Hydroxy-2'-deoxy-2-amino-2-deoxo-2,3-didehydrouridine; NSC 529488; 2-Amino-1-(β-D-arabinofuranosyl)-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 10212-30-3. Molecular formula: C9H13N3O5. Mole weight: 243.22.
Arabinosyluridine-5'-triphosphate (triethylammonium salt form)
An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Synonyms: Ara-UTP (triethylammonium salt form); Arabinofuranosyluridine triphosphate triethylammonium; 2'ara-UTP triethylammonium. Grades: 95%. Molecular formula: C9H15N2O15P3.C6H15N. Mole weight: 484.144 (free acid).
Arabinoxylan
Arabinoxylan is a multifaceted and remarkable natural polysaccharide originating from botanical sources is arabinoxylan manifesting immense potential within the biomedical arena. Its scientifically substantiated anti-inflammatory prowess coupled with its unrivaled antioxidant attributes render it an invaluable asset in combatting a myriad of afflictions. CAS No. 9040-27-1. Molecular formula: C40H64O32.
ara-cAMP
ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls. Synonyms: Arabinoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 32465-18-2. Molecular formula: C10H11N5O6P·Na. Mole weight: 351.2.
Arachidic acid
Arachidic acid (CAS# 506-30-9) is a saturated fatty acid and a minor constituent of peanut oil, coconut oil and corn oil. Arachidic acid is used for the production of detergents, photographic materials and lubricants. Synonyms: icosanoic acid. Grades: > 98.0 % (GC) (T). CAS No. 506-30-9. Molecular formula: C20H40O2. Mole weight: 312.53.
Arachidonic acid
Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Synonyms: Arachidonate. Grades: 98 %. CAS No. 506-32-1. Molecular formula: C20H32O2. Mole weight: 304.47.
Arachidonic acid-[13C20]
Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Grades: > 98%. Molecular formula: [13C]20H32O2. Mole weight: 324.32.
Arachidonoyl amide
Arachidonamide (AEA) is a weak cannabinoid CB1 and CB2 agonist. Arachidonamide was hydrolyzed by FAAH more effectively than AEA but exhibited significantly weaker binding to the human CB1 receptor with a Ki of 9.6 μM. AEA also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 μM. Arachidonamide are found to be the best substrates for anandamide amidohydrolase (AAH) with relative rates of hydrolysis about twice that of anandamide. Synonyms: Arachidonamide; Arachidonic acid amide; 5Z,8Z,11Z,14Z-eicosatetraenamide. Grades: ≥98%. CAS No. 85146-53-8. Molecular formula: C20H33NO. Mole weight: 303.5.
Ara-CTP
ara-Cytidine-5'-triphosphate (ara-CTP) is an inhibitor of DNA synthesis, DNA ligases and polymerases that is used for the treatment of acute myeloid leukemia. Uses: Nucleic acid synthesis inhibitors. Synonyms: 1-β-D-arabinofuranosylcytosine TP; Aracytidine-5'-Triphosphate; ara-Cytidine-5'-triphosphate; Arabinofuranosylcytosine triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 13191-15-6. Molecular formula: C9H16N3O14P3 (free acid). Mole weight: 483.15 (free acid).
ara-Cytidine-5'-diphosphate (ara-CDP)
Ara-Cytidine-5'-diphosphate (ara-CDP), an innovative nucleotide analog, plays a crucial role in the realm of anti-cancer therapy by thwarting DNA synthesis and triggering apoptosis in cancer cells. Known for its efficacy in treating acute myeloid leukemia and non-Hodgkin lymphoma, this compound is available in several formats and can be delivered through both oral and injection routes. Its versatile therapeutic potential has revolutionized cancer treatment paradigms by novelly combining precise cellular targeting with extensive delivery options. Synonyms: Cytarabine diphosphate; Cytidine-arabinofuranoside-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H15N3O11P2 (free acid). Mole weight: 403.17 (free acid).
Ara-GTP
Ara-GTP serves as an antimetabolite for targeted cancer treatment. Its mechanism of action involves the interruption of DNA synthesis as well as the initiation of cell death in fast-replicating cancerous cells. With its specificity towards leukemia and lymphoma, it successfully hinders the generation of new malignant cells by inhibiting crucial DNA precursors. Synonyms: Araguanosine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O14P3. Mole weight: 523.1.
Araguspongin B
Araguspongin B is a compound isolated from Pacific basin sponges. It shows notable vasodilatory properties. Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level with an IC50 value of 0.6 μM in cerebral microsomes. It is nearly as potent as xestospongin C as an antagonist of the IP3 receptor. Grades: ≥90%. CAS No. 123000-02-2. Molecular formula: C28H50N2O2. Mole weight: 446.7.
Aranciamycin A
Aranciamycin A is an anthracyclic antibiotic originally isolated from Streptomyces. It is active against M. bovis and B. subtilis (MICs = 30 and 7.5 μM, respectively) but not S. aureus, E. coli, P. aeruginosa, or C. albicans (MICs = >30 μM for all). Synonyms: (8R,10S)-10-[(6-deoxy-2-O-methyl-alpha-L-mannopyranosyl)oxy]-7,8,9,10-tetrahydro-1,8,11-trihydroxy-8-methyl-5,12-naphthacenedione. Grades: >95%. CAS No. 960622-70-2. Molecular formula: C26H28O10. Mole weight: 500.49.
Aranochlor A
Aranochlor A is an antibiotic produced by Pseudoarachniotus roseus (HIL Y-30499). It has activity against gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis and Micrococcus luteus and Saccharomyces cerevisiae. No effect on other Gram-negative bacteria and fungi. Molecular formula: C23H32ClNO5. Mole weight: 437.96.
Aranochlor B
Aranochlor B is an antibiotic produced by Pseudoarachniotus roseus (HIL Y-30499). It has activity against gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis and Micrococcus luteus and Saccharomyces cerevisiae. No effect on other Gram-negative bacteria and fungi. Molecular formula: C23H32ClNO5. Mole weight: 437.96.