BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
LZ1 peptide
LZ1 peptide is a synthetically derived antimicrobial peptide. It is known for its potent bactericidal effects, broad-spectrum antimicrobial activity, and lack of hemolytic activity and toxicity towards eukaryotic cells. It also exhibits anti-inflammatory properties by inhibiting the secretion of inflammatory factors such as tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-1β, which can help in managing inflammation caused by acne. LZ1 peptide is a potent antimicrobial agent used in cosmetics for its ability to combat acne-causing bacteria and reduce inflammation. It is known for its effectiveness in treating inflammatory acne, improving skin texture, and potentially reducing the appearance of acne scars. Additionally, LZ1 peptide contributes to skin health by providing antioxidant properties and combating free radicals, which can help prevent skin aging and soothe sun-induced damage. Alternative Names: LZ1 antimicrobial peptide; Antimicrobial peptide LZ1 peptide; LZ1; H-Val-Lys-Arg-Trp-Lys-Lys-Trp-Trp-Arg-Lys-Trp-Lys-Lys-Trp-Val-NH2; H-VKRWKKWWRKWKKWV-NH2; L-Valyl-L-lysyl-L-arginyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-arginyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-L-valinamide; Val-Lys-Arg-Trp-Lys-Lys-Trp-Trp-Arg-Lys-Trp-Lys-Lys-Trp-Val-NH2. Grades: ≥95%. CAS No. 1423743-97-8. Molecular formula: C113H167N33O15. Mole weight: 2227.75.
MAC glucuronide linker-2
MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: (2S,3R,4S,5S,6S)-2-(2-Amino-4-(hydroxymethyl)phenoxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. Grades: >99.3%. CAS No. 229977-57-5. Molecular formula: C20H25NO11. Mole weight: 455.41.
Maclurin
Maclurin is a natural xanthones found in the ranch of Morus alba L. Due to ortho-dihydroxyl groups and ultimately to the relative stability of the ortho-benzoquinone form, maclurin has protective and antioxidant effects. Maclurin also exhibits the activit. Uses: Antioxidant. Alternative Names: 2,3',4,4',6-Pentahydroxybenzophenone. Grades: >98%. CAS No. 519-34-6. Molecular formula: C13H10O6. Mole weight: 262.2.
Madecassic acid
Madecassic acid is a natural triterpenoid found in the herbs of Centella asiatica (L.) Urban. Madecassic acid has strong metabolic capacity. Madecassic acid is used as a wound-healing, anti-inflammatory and anti-cancer agent. Alternative Names: (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid; Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-; Urs-12-en-28-oic acid, 2α,3β,6β,23-tetrahydroxy-; Brahmic acid; (2α,3β,4α,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid; 2α,3β,6β,23-Tetrahydroxy-urs-12-en-28-oic acid; 6β-Hydroxyasiatic acid; NSC 88135. Grades: >98%. CAS No. 18449-41-7. Molecular formula: C30H48O6. Mole weight: 504.70.
Madecassoside
Madecassoside is a neuroprotective and may be useful in reducing the damage caused by stroke. Madecassoside also has whitening effect, thus can be used in cosmetic material. Uses: Anti-arthritis. Alternative Names: 6-Deoxy-a-L-mannopyranosyl-1-4-b-D-glucopyranosyl-1-6-b-D-glucopyranosyl-(2a,3b,4a,6b)-2,3,6,23-tetrahydroxyurs-12-en-28-oate. Grades: >98%. CAS No. 34540-22-2. Molecular formula: C48H78O20. Mole weight: 975.12.
Maduramicin Ammonium
Maduramcin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis. It is a polyether antibiotic chemically related to the Lonomycins. Uses: Anti-bacterial agents. Alternative Names: Cygro; Maduramicin α, Monoammonium Salt; Prinicin Ammonium; CL 259971; Lonomycin A, 23,27-didemethoxy-2,6,22-tridemethyl-11-O-demethyl-22-((2,6-dideoxy-3,4-di-O-methyl-beta-L-arabino-hexopyranosyl)oxy)-6-methoxy-, monoammonium salt, (3R,4S,5S,6R,7S,22S)-. Grades: >95%. CAS No. 84878-61-5. Molecular formula: C47H83O17N. Mole weight: 934.16.
Maesopsin
Maesopsin is a natural compound isolated from Hoveniae Lignum. Alternative Names: 3(2H)-Benzofuranone, 2,4,6-trihydroxy-2-((4-hydroxyphenyl)methyl)-. Grades: 98.0%. CAS No. 5989-16-2. Molecular formula: C15H12O6. Mole weight: 288.25.
Magainin I
Magainin I is a peptide antibiotic with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis. It has a broad spectrum of non-specific activity against a variety of microorganisms, including viruses, gram-positive and gram-negative bacteria, protozoa, yeast and fungi, and may also have hemolytic and cytotoxicity to cancer cells. Magainin 1 is a fungicide. Magainin 1 has an inhibitory effect on herpes simplex virus type 1 (HSV-1) and HSV-2. Alternative Names: H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser-OH; glycyl-L-isoleucyl-glycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-histidyl-L-seryl-L-alanyl-glycyl-L-lysyl-L-phenylalanyl-glycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-methionyl-L-lysyl-L-serine; Magainin 1 peptide, Xenopus. Grades: >95%. CAS No. 108433-99-4. Molecular formula: C112H177N29O28S. Mole weight: 2409.85.
Magainin II
Magainin II is a broad-spectrum antibiotic isolated from Xenopus laevis. It has anti-fungal and anti-cancer activity in vitro. Alternative Names: Magainin 2; magainin 2 peptide, Xenopus; Z-12 Peptide; Mag-2; Magainin I, 10-L-lysine-22-L-asparagine-; H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH; glycyl-L-isoleucyl-glycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-histidyl-L-seryl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanyl-glycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-methionyl-L-asparagyl-L-serine. Grades: ≥97% by HPLC. CAS No. 108433-95-0. Molecular formula: C114H180N30O29S. Mole weight: 2466.89.
Magnolol is a bioactive lignin found in Magnolia officinalis and acts as a TNF-α and nitric oxide (NO) inhibitor. It exhibits potential therapeutic effect on anxiety, cough, headache and allergies. Magnolol has antifungal, antibacterial, anti-oxidative, antidepressant-like, anti-tumor, and neuroprotective effects. It can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products. Uses: Anti-oxidative; antimicrobial; antifungal. Alternative Names: 5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol; 5,5'-Diallyl-2,2'-biphenyldiol; 5,5'-Diallyl-2,2'-dihydroxybiphenyl; 2,2'-Bichavicol; 2,2'-Bichavicol; 5,5'-Di-2-propen-1-yl[1,1'-biphenyl]-2,2'-diol; E 100338; NSC 293099. Grades: >95%. CAS No. 528-43-8. Molecular formula: C18H18O2. Mole weight: 266.34.
Mahanine
Mahanine, a carbazole alkaloid (occurs in the edible part of Micromelum minutum, Murraya koenigii and related species), is a DNA minor groove binding agent with potent anticancer activity. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection treatment research. Alternative Names: (-)-Mahanine; (R)-3,5-Dimethyl-3-(4-methylpent-3-en-1-yl)-3,11-dihydropyrano[3,2-a]carbazol-9-ol. Grades: 95%. CAS No. 28360-49-8. Molecular formula: C23H25NO2. Mole weight: 347.46.
Mal-amido-PEG8-acid
Mal-amido-PEG8-acid is a PEG derivative containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Alternative Names: Mal-amido-PEG8-C2-acid; 3-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid. Grades: >97%. CAS No. 1334177-86-4. Molecular formula: C26H44N2O13. Mole weight: 592.63.
Maleimide-NH-PEG10-CH2CH2COONHS Ester
Maleimide-NH-PEG10-CH2CH2COONHS Ester is a versatile bioactive ester that can be used to develop targeted drug delivery systems. It acts as a linker to bind drugs or imaging agents to targeting molecules, facilitating their selective delivery to specific cells or tissues. In addition, it can be used in the development and synthesis of cancer treatment drugs. Alternative Names: Alpha-Maleimidopropionyl-Omega-succinimidyl-10(ethylene glycol) ; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate. Grades: ≥98%. CAS No. 1137109-22-8. Molecular formula: C34H55N3O17. Mole weight: 777.81.
Malformin C
Malformin C is a fungal cyclic pentapeptide with antibacterial and anticancer activities. Study shows that Malformin C inhibits cell growth in Colon 38 and HCT 116 cells in a dose-dependent manner with IC50 of 0.27±0.07μM and 0.18±0.023μM, respectively. Alternative Names: Malformin B1b; Cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl) Cyclic (1→2)-Disulfide; (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-]. Grades: ≥95%. CAS No. 59926-78-2. Molecular formula: C23H39N5O5S2. Mole weight: 529.72.
Mal-L-PA-NH-Boc
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: 2-(2,5-dioxopyrrol-1-yl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. CAS No. 1491152-23-8. Molecular formula: C12H16N2O6. Mole weight: 284.27.
Mal-NH-PEG2-BCN
Mal-NH-PEG2-BCN is an ADC Linker containing 2 PEG units. Alternative Names: BCN-exo-PEG2-maleimide. CAS No. 2141976-22-7. Molecular formula: C24H33N3O7. Mole weight: 475.53.
Mal-PEG4-NHS
Mal-PEG4-NHS is a non-cleavable ADC linker containing the Maleimide group, 4-unit PEG, and NHS ester. Alternative Names: Mal-PEG4-NHS ester; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12-tetraoxapentadecan-15-oate; 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate; 1-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 1-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-. Grades: ≥98%. CAS No. 1325208-25-0. Molecular formula: C19H26N2O10. Mole weight: 442.42.
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin SA, linked via Mal-PEG4-VC-PAB-DMEA-Seco. Grades: >98.0%. CAS No. 2259318-49-3. Molecular formula: C67H87ClN12O21. Mole weight: 1431.93.
Mal-PEG8-NHS
Mal-PEG8-NHS is a biochemical product widely used in drug delivery and in-depth biopharmaceutical research. As a polyethylene glycol (PEG) derivative conjugated to a maleimide moiety, it is widely used in drug delivery systems and bioconjugation. Alternative Names: Maleimide-PEG8-succinimidyl ester; 4,7,10,13,16,19,22,25-Octaoxa-28- azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-, 2,5-dioxo-1-pyrrolidinyl Ester. Grades: ≥98%. CAS No. 756525-93-6. Molecular formula: C30H47N3O15. Mole weight: 689.71.
Mal-PEG-NHS
Mal-PEG-NHS is a bioconjugation reagent widely used in the biomedical industry. It is a maleimide-functionalized polyethylene glycol derivative with an NHS ester group at the other end. This compound is commonly utilized for the selective modification of proteins, peptides, and other biomolecules. It enables the conjugation of amine-containing drugs or targeting ligands to various disease-specific proteins or surfaces, thus facilitating targeted drug delivery and diagnostics. Alternative Names: (2,5-dioxopyrrolidin-1-yl) 3-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]propanoate;2,5-dioxopyrrolidin-1-yl 3-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)propanoate. Grades: 95%. CAS No. 1260092-50-9. Molecular formula: C16H19N3O8. Mole weight: 381.34.
Maltol
Maltol is a fragrance molecule used in flavor enhancers and fragrances. Uses: Antioxidant. Alternative Names: 3-Hydroxy-2-methyl-4H-pyran-4-one; 2-Methyl-3-hydroxy-4-pyrone; 2-Methyl-3-hydroxypyran-4-one; 3-Hydroxy-2-methyl-1,4-pyrone; Larixic Acid; Larixin; Palatone; Veltol. Grades: 98%. CAS No. 118-71-8. Molecular formula: C6H6O3. Mole weight: 126.11.
Mancozeb is a fungicide used to protect crops in agriculture. Alternative Names: Manganese Zinc ethylenebis(dithiocarbamate). CAS No. 8018-1-7. Molecular formula: C8H12MnN4S8Zn. Mole weight: 541.1.
Mangiferin
Mangiferin is a natural xanthone isolated from Anemarrhena asphodeloides Bunge rhizome. The distinctive gold-orange fluorescence of Mangiferin under ultraviolet light , it has been used to aid in the chromatographic identification of hybrid Aspleniums. Uses: Antidiabetic, anthelminthic, antiallergic. Alternative Names: 2-b-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-Xanthen-9-one; Mangiferin; Alpizarine. Grades: 95%. CAS No. 4773-96-0. Molecular formula: C19H18O11. Mole weight: 422.34.
Manool
Manool is a plant metabolite with antibacterial and antineoplastic activity. Alternative Names: (3R)-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-1-en-3-ol. Grades: 95%. CAS No. 596-85-0. Molecular formula: C20H34O. Mole weight: 290.48.
MA-PEG4-vc-PAB-DMEA-duocarmycin DM
MA-PEG4-vc-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Alternative Names: Mal-PEG4-vc-PAB-DMEA-duocarmycin DM. Grades: 95%. Molecular formula: C68H89ClN12O17. Mole weight: 1381.98.
MA-PEG4-vc-PAB-DMEA-duocarmycin SA
MA-PEG4-vc-PAB-DMEA-duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Alternative Names: Mal-PEG4-vc-PAB-DMEA-duocarmycin SA. Grades: 95%. Molecular formula: C67H87ClN12O21. Mole weight: 1431.94.
MA-PEG4-vc-PAB-DMEA-duocarmycin TM
MA-PEG4-vc-PAB-DMEA-duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Alternative Names: Mal-PEG4-vc-PAB-DMEA-duocarmycin TM. Molecular formula: C67H86ClN11O19. Mole weight: 1384.93.
MA-PEG4-VC-PAB-DMEA-PNU159682
MA-PEG4-VC-PAB-DMEA-PNU159682 is a drug-linker conjugate for ADC by using PNU159682 (a potent DNA topoisomerase II inhibitor), linked via MA-PEG4-VC-PAB-DMEA. Alternative Names: Mal-PEG4-VC-PAB-DMEA-PNU-159682. CAS No. 2259318-52-8. Molecular formula: C74H98N10O27. Mole weight: 1559.64.
Marbofloxacin
Marbofloxacin is a third generation fluoroquinolone antibiotic. Marbofloxacin exhibits high bactericidal activity against a broad spectrum of aerobic Gram-negative and some Gram-positive bacteria, as well as Mycoplasma spp. Uses: Anti-bacterial agents. Alternative Names: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic Acid; Marbocyl; Zeniquin; Marbofloxacinum. Grades: >98%. CAS No. 115550-35-1. Molecular formula: C17H19FN4O4. Mole weight: 362.36.
Maslinic acid
Maslinic acid is a pentacyclic triterpene found in a variety of natural sources. It exerts a wide range of biological activities, such as antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. Uses: Antioxidant; anti-hiv. Alternative Names: Crategolic acid; 2α-Hydroxyoleanolic acid. Grades: >98%. CAS No. 4373-41-5. Molecular formula: C30H48O4. Mole weight: 472.7.
Mastoparan
Mastoparan, a tetradecapeptide which is a component of wasp venom, activates Gi and Go and has been shown to cause an increase in the production of Arachidonic Acid catalyzed by PLA2 from porcine pancreas and bee venom. Alternative Names: H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2; L-isoleucyl-L-asparagyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-isoleucyl-L-leucinamide. Grades: ≥95%. CAS No. 72093-21-1. Molecular formula: C70H131N19O15. Mole weight: 1478.91.
Matrine
Matrine ((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist. Uses: Anticancer. Alternative Names: Matridin-15-one; Matrine; NSC 146051; NSC146051; NSC-146051. Grades: >98%. CAS No. 519-02-8. Molecular formula: C15H24N2O. Mole weight: 248.36.
Matrixyl 3000
Matrixyl 3000 is an anti-aging ingredient developed by Sederma. Matrixyl 3000 is a combination of palmitoyl oligopeptide and palmitoyl tetrapeptide-7. Grades: 98%.
Mauritianin
Mauritianin is a compound of the flavonoid class found in the herbs of Hypericum japonicum Thunb. Mauritianin is a topoisomerase I inhibitor. Alternative Names: 5,7-dihydroxy-3-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy]oxan-2-yl]oxy-2-(4-hydroxyphenyl)chromen-4-one. Grades: >98%. CAS No. 109008-28-8. Molecular formula: C33H40O19. Mole weight: 740.664.
Maxadilan
Maxadilan, a potent vasodilator isolated from the salivary glands of the sand fly Lutzomyia longipalpis, specifically and effectively activates the mammalian PAC1 receptor, one of the three receptors of PACAP. Alternative Names: H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Leu-Gln-Thr-Ser-Val-Gln-Thr-Thr-Ala-Thr-Phe-Thr-Ser-Met-Asp-Thr-Ser-Gln-Leu-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys51); Maxadilan (Lutzomyialongipalpis); L-cysteinyl-L-alpha-aspartyl-L-alanyl-L-threonyl-L-cysteinyl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-alanyl-L-isoleucyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-glutaminyl-L-lysyl-L-glutaminyl-L-alanyl-L-histidyl-L-histidyl-L-seryl-L-asparagyl-L-valyl-L-leucyl-L-glutaminyl-L-threonyl-L-seryl-L-valyl-L-glutaminyl-L-threonyl-L-threonyl-L-alanyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-methionyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-glutaminyl-L-leucyl-L-prolyl-glycyl-L-asparagyl-L-seryl-L-valyl-L-phenylalanyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-methionyl-L-lysyl-L-glutaminyl-L-lysyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-alaninamide (1->5),(14->51)-bis(disulfide). Grades: 95%. CAS No. 135374-80-0. Molecular formula: C291H466N86O94S6. Mole weight: 6865.82.
Maytansinol
Maytansinol is an ansamacrolide isolated from P. verrucose. It was shown to inhibit microtubule assembly and induces microtubule disassembly in vitro. It exhibits antitumor activity. Alternative Names: (3S)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-maytansine; Ansamitocin P-0; NSC239386; NSC-239386; Maytansine; Ansamitocin P 0; Antibiotic C 15003P; NSC 239386. Grades: 95%. CAS No. 57103-68-1. Molecular formula: C28H37ClN2O8. Mole weight: 565.06.
Mazdutide
Mazdutide is a long-acting glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. Mazdutide has been use in the research of type 2 diabetes mellitus (T2DM). Alternative Names: IBI362; IBI 362; IBI-362; LY3305677; LY 3305677; LY-3305677; OXM3; OXM-3; OXM 3. CAS No. 2259884-03-0. Molecular formula: C207H317N45O65. Mole weight: 4476.
Mca-(Ala7,Lys(Dnp)9)-Bradykinin
Mca-(Ala7,Lys(Dnp)9)-Bradykinin is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1), a membrane-bound zinc metallopeptidase related to neprilysin in amino acid sequence. It is used as a substrate for insulin-degrading enzymes (IDE) and ACE2. Alternative Names: Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH; N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine; (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl); N2-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine. Grades: 95%. CAS No. 323577-36-2. Molecular formula: C66H81N15O19. Mole weight: 1388.44.
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
Mca-KPLGL-Dpa-AR-NH2 is an N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH2 with a Lys yields a fluorogenic peptide with improved substrate properties. Compared with Mca-PLGL-Dpa-AR-NH2, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH2 for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased by 2-9 times and 3 times, respectively, while those for gelatinases and matrilysin remain equally high. Alternative Names: L-Argininamide, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-; N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-L-argininamide; MMPs substrate Fluorogenic. Grades: ≥95%. CAS No. 720710-69-0. Molecular formula: C55H80N16O16. Mole weight: 1221.32.
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: (R)-10-Benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosanoic acid. CAS No. 1802520-40-6. Molecular formula: C28H36N6O10. Mole weight: 616.62.
Mc-MMAE
Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Alternative Names: Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥98%. CAS No. 863971-24-8. Molecular formula: C49H78N6O10. Mole weight: 911.18.
MC-Val-Ala-PBD
MC-Val-Ala-PBD is a protective group conjugated PBD, PBD bind in the minor groove of DNA. Alternative Names: L-Alaninamide, N-(6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl)-L-valyl-N-(4-((11aS)-8-(3-(((11aS)-5,11a-dihydro-7-methoxy-2-(4-methoxyphenyl)-5-oxo-1H-pyrrolo(2,1-C)(1,4)benzodiazepin-8-yl)oxy)propoxy)-5,11a-dihydro-7-methoxy-5-oxo-1H-pyrrolo. Grades: ≥98%. CAS No. 1342820-51-2. Molecular formula: C60H64N8O12. Mole weight: 1089.20.
MC-Val-Cit-PAB
MC-Val-Cit-PAB. Alternative Names: L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-; N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide; 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino]-1-oxo-5-ureidopentan-2-yl)amino]-3-methyl-1-oxobutan-2-yl)hexanamide; N-[(1S)-1-[[(1S)-4-(carbamoylamino)-1-[[4-(hydroxymethyl)phenyl]carbamoyl]butyl]carbamoyl]-2-methylpropyl]-6-(2,5-dioxopyrrol-1-yl)hexanamide. Grades: ≥95%. CAS No. 159857-80-4. Molecular formula: C28H40N6O7. Mole weight: 572.65.
MC-Val-Cit-PAB-duocarmycin
MC-Val-Cit-PAB-duocarmycin is a drug-linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. Alternative Names: MC Val Cit PAB duocarmycin. CAS No. 2055896-98-3. Molecular formula: C54H65ClN9O9. Mole weight: 1019.6.
MC-Val-Cit-PAB-MMAE
MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. Alternative Names: VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Vedotin. Grades: 95%. CAS No. 646502-53-6. Molecular formula: C68H105N11O15. Mole weight: 1316.63.
MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF is a potent tubulin inhibitor (MMAF), Val-Cit-PAB-MMAF is an antibody drug conjugate. Alternative Names: MC-VC-PAB-MMAF. Grades: ≥98%. CAS No. 863971-17-9. Molecular formula: C68H103N11O16. Mole weight: 1330.6.
MC-VC-PAB-Azide
MC-VC-PAB-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Grades: 98.0%. Molecular formula: C33H48N10O9. Mole weight: 728.80.
MC-vc-PAB-C6-a-amanitin
MC-vc-PAB-C6-a-amanitin is a drug-linker conjugate for ADC by using a-amanitin (a potent bicyclic octapeptide cytotoxin), linked via MC-vc-PAB-C6. Molecular formula: C74H105N17O22S. Mole weight: 1616.81.
MC-VC-PABC-MMAE
MC-VC-PABC-MMAE is a potent and selective antibody-drug conjugate (ADC) used in the treatment of various cancers, including breast cancer, ovarian cancer, and non-small cell lung cancer. It combines the efficacy of a monoclonal antibody with the cytotoxicity of a potent chemotherapeutic agent, delivering targeted therapy directly to cancer cells while minimizing systemic side effects. MC-VC-PABC-MMAE specifically targets cancer cells overexpressing certain antigens, making it a promising option for personalized cancer treatment. Alternative Names: MC-Val-Cit-PABC-MMAE; N-[[[4-[[N-[6-(2,5-Dioxo-1-pyrrolidinyl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide. CAS No. 1703779-06-9. Molecular formula: C68H107N11O15. Mole weight: 1318.64.
MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA
MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via MC-vc-PAB-DMEA-(PEG2). Molecular formula: C62H78ClN11O18. Mole weight: 1300.82.
MC-VC-PAB-NH2 TFA
MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[(2-aminoethyl)amino]carbonyl]oxy]methyl]phenyl]-, 2,2,2-trifluoroacetate (1:1). CAS No. 1616727-21-9. Molecular formula: C33H47F3N8O10. Mole weight: 772.77.
MC-vc-PAB-(PEG2)-duocarmycin DM
MC-vc-PAB-(PEG2)-duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via MA-MC-vc-PAB-(PEG2). Molecular formula: C63H80ClN11O14. Mole weight: 1250.85.
MC-vc-PAB-(PEG2)-duocarmycin TM
MC-vc-PAB-(PEG2)-duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via MA-MC-vc-PAB-(PEG2). Molecular formula: C62H77ClN10O16. Mole weight: 1253.80.
Mc-VC-PAB-SN38
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl [(19S)-10,19-diethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-19-yl] carbonate. Grades: >98.0%. CAS No. 1801838-28-7. Molecular formula: C51H58N8O13. Mole weight: 991.05.
Mebendazole
Mebendazole is a benzimidazole anthelmintic and Tubulin-disrupting drug. It has antitumour activity in vitro and in vivo and inhibits growth and induces apoptosis. It is highly effective on various gastrointestinal nematodes in animals, has good effects on some tapeworms, and also effective on Trichinella spiralis. It is used for nematode diseases of horses, sheep, poultry and wild animals, nematodes and tapeworms of dogs and cats. Alternative Names: Vermox; Telmin; Mebenvet; Pantelmin; Vermirax; Ovitelmin; Bantenol; Lomper; MBDZ; Besantin; Noverme; Methyl (5-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate; Sufil; 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester. Grades: >98%. CAS No. 31431-39-7. Molecular formula: C16H13N3O3. Mole weight: 295.29.
Medicarpin
Medicarpin isolated from the herb of Hedysarum polybotrys Hand. -Mazz. It stimulates osteoblast differentiation via ERβ, and promotes achievement of peak bone mass. Uses: Potential osteogenic agent. Alternative Names: 3-HYDROXY-9-METHOXYPTEROCARPAN;[6aR,11aR,(-)]-6a,11a-Dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol. Grades: 0.99. CAS No. 32383-76-9. Molecular formula: C16H14O4. Mole weight: 270.3.
Medioresinol
Medioresinol isolated from the herbs of Allamanda neriifolia. It possesses a lesishmanicidal activity and cardiovascular disease risk reduction. Uses: Anti-bacterial, antifungal and anti-biofilm activities. Alternative Names: 4-[(1S,3aR,4S,6aR)-4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H- furo[3,4-c]furan-1-yl]-2,6-dimethoxyphenol. Grades: 97.5%. CAS No. 40957-99-1. Molecular formula: C21H24O7. Mole weight: 388.4.
Medroxyprogesterone Acetate EP Impurity G
Medroxyprogesterone Acetate EP Impurity G is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2. Medroxyprogesterone Acetate EP Impurity G is a manufactured hormone of the progestin type. Alternative Names: Medroxyprogesterone Acetate Impurity G; 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate; Megestrol acetate; Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-; 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione; Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, acetate; 17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione; 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate; 17α-Acetoxy-6-dehydro-6-methylprogesterone; 17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione; 17α-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate; 6-Dehydro-6-methyl-17α-acetoxyprogesterone; 6-Methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione; 6-Methyl-17α-hydroxy-Δ6-progesterone acetate; 6-Methyl-6-dehydro-17α-acetoxyprogesterone; 6-Methyl-Δ4,6-pregnadien-17α-ol-3,20-dione acetate; BDH 1298; DMAP; Magestin; Maygace; Megace; Megalia; Megeron; Megestat; Megestil; Megestin; Megestryl acetate; MGA; Nia; Niagestin; NSC 71423; Ovaban; Ovarid; Medroxy Progesterone EP Impurity G. Grades: 98%. CAS No. 595-33-5. Molecular formula: C24H32O4. Mole weight: 384.51.
Mefenamic acid
Mefenamic acid is a competitive inhibitor of COX-1 and COX-2. Uses: Anti-inflammatory agents, non-steroidal; cyclooxygenase inhibitors. Alternative Names: CI 473; CN-35355; CI473; CN35355; CI-473; CN 35355; Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-. Grades: 98.0%. CAS No. 61-68-7. Molecular formula: C15H15NO2. Mole weight: 241.29.
Melanotan I
A synthetic analogue of α-melanocyte stimulating hormone (α-MSH). Alternative Names: Afamelanotide acetate; (Nle4,D-Phe7)-α-MSH; NDP-MSH. Grades: ≥95% by HPLC. CAS No. 75921-69-6. Molecular formula: C78H111N21O19. Mole weight: 1646.85.
Melanotan (MT)-II
Melanotan II is a potent full agonist of melanocortin-3 and melanocortin-4 receptors (Ki= 6.6, 34 for MC4, MC3 receptors respectively). Melanotan II stimulates erectile activity, and inhibits food intake and displays neuroprotective properties in vivo. Alternative Names: Melanotan II; MTII, Bremelanotide amide; Melanotan-II; MelanotanII; Ac-[Nle4Asp5D-Phe7Lys10]α-MSH-(4-10)-NH2; Ac-Nle-Asp-His-d-Phe-Arg-Trp-Lys-NH2, (2→7)-lactam. Grades: 98%. CAS No. 121062-08-6. Molecular formula: C50H69N15O9. Mole weight: 1024.18.
Melatonin
Melatonin is a hormone produced in the brain by the pineal gland from the amino acid tryptophan. It can be used as an antioxidant. Melatonin is involved in many biological functions such as circadian rhythm, sleep, the stress response, aging, and immunity. Melatonin's antioxidant defense system can interrupt free radical chain reactions, remove free radicals, and play an anti-aging and anti-wrinkle role. It can inhibit the production of a variety of inflammatory factors, and has the effect of eliminating inflammation and whitening spots. In addition, it can promote hair growth and care for hair. Uses: Ingredient of health care products. Alternative Names: Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-; 3-(2-Acetamidoethyl)-5-methoxyindole; 5-Methoxy-N-acetyltryptamine; Circadin; Melatol; Melatonine; Melaxen; Melovine; N-[2-(5-Methoxyindol-3-yl)ethyl]acetamide; N-Acetyl-5-methoxytryptamine; NSC 113928; NSC 56423; Regulin; Slenyto; ML-236B; ML 236B; ML236B. Grades: >98%. CAS No. 73-31-4. Molecular formula: C13H16N2O2. Mole weight: 232.28.
Melengestrol acetate-[d3]
Labelled form of Melengestrol acetate. Melengestrol acetate is used as an orally active progestational steroid. Alternative Names: 17-(Acetyloxy-d3)-6-methyl-16-methylenepregna-4,6-diene-3,20-dione; 17-Hydroxy-6-methyl-16-methylenepregna-4,6-diene-3,20-dione Acetate-d3; 17-(Acetoxy-d3)-6-methyl-16-methylenepregna-4,6-diene-3,20-dione; 6-Dehydro-16-methylene-17α-hydroxy-6α-methylprogesterone Acetate-d3; Heifermax 500-d3; NSC-70968-d3. Grades: ≥98% by CP; ≥98% atom D. Molecular formula: C25H29D3O4. Mole weight: 399.54.
Melittin
Melittin is an oligopeptide constituent discovered within the venom of bees, showcasing remarkable characteristics encompassing its effectiveness against microbes, viruses and cancer cells. Its capacity to assail cellular membranes renders Melittin a prospective tool in studying an array of ailments such as cancer, HIV and drug-resistant infections. Alternative Names: melittinfrombeevenomsequencing*grade; melittinhoneybeevenom; melittin-t; H-GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN-NH2. CAS No. 37231-28-0. Molecular formula: C131H229N39O31. Mole weight: 2846.46.
Melittin is a polypeptide isolated from the venom of the honey bee (Apis mellifera). It inhibits protein kinase C, Ca2+ / calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane). Alternative Names: Honeybee melittin; Bee venom melittin; Forapin; H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2; glycyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonyl-glycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutaminamide. Grades: ≥98%. CAS No. 20449-79-0. Molecular formula: C131H229N39O31. Mole weight: 2846.46.
Melittin-like peptide
Melittin-like peptide is isolated from Rana temporaria which has antimicrobial activity. Alternative Names: MLP.