BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Microcystin-LA-[15N7] | Microcystin-LA-[15N7] is a 15N labelled Microcystin-LA, which is an analog of the major microcystin-LR with the substitution of alanine in place of the arginine. It inhibits both PP1C and PP2A with IC50 value of 0.3 nM. Alternative Names: Cyanoginosin LA-15N7. Grades: 95% by CP; 97% atom 15N. Molecular formula: C46H67[15N]7O12. Mole weight: 917.02. |  |
| Midostaurin | Midostaurin is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus. Alternative Names: PKC412; PKC-412; PKC 412; PKC412A; PKC-412A; PKC 412A; CGP41251; CGP 41251; CGP-41251; Benzoylstaurosporine; 4'-N-Benzoylstaurosporine. Grades: ≥98%. CAS No. 120685-11-2. Molecular formula: C35H30N4O4. Mole weight: 570.65. | |
| Mifepristone | Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Uses: Mifepristone is used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. it has occasionally been used in refractory cushing's syndrome. it is used in combination with misoprostol for the oral induction of first trimester abortions. it induces growth arrest, caspase activation, and cell death in anti-estrogen-resistant breast cancer cells, which indicats the effectiveness of pr antagonism as a novel approach to treatment of select cancers. Alternative Names: (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one; RU-486; RU-38486; Mifegyne; Mifeprex; Mifestone; VGX 410. Grades: > 95%. CAS No. 84371-65-3. Molecular formula: C29H35NO2. Mole weight: 429.60. | |
| Milbemectin | It is a mixture of the two most abundant milbemycin analogues, A3 and A4. It is the macrolide antibiotic produced by streptomyces hydroscopicus subsp. Aureolarcrimosus. It is a highly selective and potent insecticide and acaricide used as an agri-chemical for crop protection. Alternative Names: Milbemycin A3 and Milbemycin A4 (Mixture); (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-milbemycin B and (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-milbemycin B (Mixture); Antibiotic B 41A3 and Antibiotic B 41A4 (Mixture). Grades: >95% by HPLC. CAS No. 1799297-76-9. Molecular formula: C31H44O7.C32H46O7. Mole weight: 1071.38. | |
| Milbemycin A3 oxime | Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A3. Milbemycin A3 oxime is the minor component of the anti-parasitic product milbemycin oxime. Alternative Names: 5-Oxomilbemycin A3 oxime; (6R,25R)-5-Demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methylmilbemycin B. Grades: >95%. CAS No. 114177-14-9. Molecular formula: C31H43NO7. Mole weight: 541.67. | |
| Milbemycin oxime | Milbemycin oxime is a semi-synthetic macrolide. As a nematocide and insecticide in veterinary medicine, it opens glutamate sensitive chloride channels in neurons of invertebrates that leads to paralysis by hyperpolarisation of these cells and signal transfer blocking. M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); Bile acid transporter: IC50=3.6 μM (human); TGR5: IC50=36.4 μM (human); HCT-116: IC50 >50 μM (human); GBM: IC50 >50 μM (human). Uses: A broad spectrum insecticide; used for treatment and prevention of heartworm in dogs and cats. Alternative Names: Milbemycin A 5-oxime; Milbemite; Trifexis; Interceptor; Milbe Mite. CAS No. 129496-10-2. Molecular formula: C126H176N4O28. Mole weight: 2194.78. | |
| Miltirone | Source from root of Salvia miltiorrhiza Bge. Miltirone may be a promising candidate for cancer chemotherapy. And it is the likely active constituent of S. miltiorrhiza responsible for the reducing effect of its extracts on alcohol intake in different experimental models of excessive alcohol consumption. Uses: Resistance to atherosclerosis and cardiac protection. Alternative Names: Miltiron; Rosmariquinone; NSC 639662. Grades: >98%. CAS No. 27210-57-7. Molecular formula: C19H22O2. Mole weight: 282.38. | |
| Minimycin | Minimycin is a nucleoside antibiotic produced by Str. hygroscopicus 80342. Broad-spectrum antibacterial activity. It has inhibitory effect on mouse Ehrlich ascites carcinoma, ascites type and solid type sarcoma-180. Alternative Names: Oxazinomycin; 2H-1,3-Oxazine-2,4(3H)-dione, 5-beta-D-ribofuranosyl-; 5-beta-D-Ribofuranosyl-1,3-oxazine-2,4-dione. CAS No. 32388-21-9. Molecular formula: C9H11NO7. Mole weight: 245.19. | |
| Minocycline | Minocycline is a broad-spectrum tetracycline antibiotic, which has a broader spectrum than the other members of the group. It is effective against tetracycline-resistant staphylococcus infections. It is a bacteriostatic antibiotic and is classified as a long-acting type. It is the most lipid-soluble of the tetracycline-class antibiotics, giving it the greatest penetration into the prostate and brain. It is not a naturally-occurring antibiotic, but was synthesized semi-synthetically from natural tetracycline antibiotics by Lederle Laboratories in 1966. It is mainly used for the treatment of acne and other skin infections. Its application is very limited because of its side effects. Alternative Names: Minostad; Akamin; Minocin; Minoderm; Cyclimycin; Solodyn; Dynacin; Sebomin; Divaine; Tigecycline EP Impurity C. Grades: 95%. CAS No. 10118-90-8. Molecular formula: C23H27N3O7. Mole weight: 457.48. | |
| Minocycline-[d6] | Minocycline-[d6] is a labelled second generation tetracycline antibiotic. Alternative Names: Minocycline D6. Grades: 95% by HPLC; 95% atom D. CAS No. 1036070-10-6. Molecular formula: C23H21D6N3O7. Mole weight: 463.51. | |
| Minocycline hydrochloride | Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells. Alternative Names: Minocycline HCl; Arestin; Minomycin. Grades: Assay 96.0%-102.5%. CAS No. 13614-98-7. Molecular formula: C23H27N3O7.HCl. Mole weight: 493.94. | |
| Minoxidil | Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Uses: Antihypertensive agents; vasodilator agents. Alternative Names: 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide; 2,4-Diamino-6-(1-piperidinyl)-pyrimidine-3-oxide; 2,4-Diamino-6-piperidinopyrimidine 3-N-oxide; 2,4-Diamino-6-piperidinopyrimidine 3-oxide; 2,6-Diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate; 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine; Alopexil; Alostil; Loniten; Lonolox; Minoximen; Mintop; Normoxidil; PDP; Pierminox; Prexidil; Regro EX 5; RiUP; Riup X5; Rogaine; Tricoxidil; U 10858. Grades: >98%. CAS No. 38304-91-5. Molecular formula: C9H15N5O. Mole weight: 209.25. | |
| Miraculin (1-20) | Miraculin is a taste improver, which is a glycoprotein extracted from the fruit of Syssepalum dulcificum. CAS No. 198694-37-0. Molecular formula: C88H146N26O34. Mole weight: 2112.28. | |
| Miramistin | Miramistin is a topical antiseptic. Alternative Names: Benzenemethanaminium, N,N-dimethyl-N-[3-[(1-oxotetradecyl)amino]propyl]-, chloride (1:1); Ammonium, benzyldimethyl(3-myristamidopropyl)-, chloride; Benzenemethanaminium, N,N-dimethyl-N-[3-[(1-oxotetradecyl)amino]propyl]-, chloride; Benzyldimethyl(3-tetradecamidopropyl)ammonium chloride; Benzyldimethyl[3-(myristoylamino)propyl]ammonium chloride; DT 2; DT 2 (surfactant). Grades: 95%. CAS No. 15809-19-5. Molecular formula: C26H47ClN2O. Mole weight: 439.12. | |
| Mitiglinide calcium | Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. Alternative Names: KAD-1229; KAD 1229; KAD1229. Grades: >98%. CAS No. 145525-41-3. Molecular formula: (C19H24NO3)2.Ca. Mole weight: 668.88. | |
| Mitomycin A | Mitomycin A is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Alternative Names: Mitomycin EP Impurity B; Mitiromycin B. Grades: > 95%. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin B | Mitomycin B is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Alternative Names: Mitomycin EP Impurity C; (1aS)-8α-[[(Aminocarbonyl)oxy]methyl]-1,1aα,2,8,8aα,8bα-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxyazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;[1aS-(1aalpha,8alpha,8aalpha,8balpha)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grades: > 95%. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin C | Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Alternative Names: Mitiromycin E; Mutamycin; Ametycine; Zilimeisu. Grades: Assay ≥ 970 mg/g Mitomycin. CAS No. 50-07-7. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| MMAE | Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. Uses: Adcs cytotoxin. Alternative Names: MMAE; Vedotin; Monomethyl auristatin E; Monomethylauristatin E; N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide. Grades: ≥98.0% by HPLC. CAS No. 474645-27-7. Molecular formula: C39H67N5O7. Mole weight: 717.98. | |
| MMAE-[13C5,15N] | MMAE-[13C5,15N] is a labelled analogue of MMAE, which is a potent mitotic inhibitor and a tubulin inhibitor. Alternative Names: [13C5,15N]-MMAE; [13C5,15N]-Monomethyl auristatin E; Monomethyl auristatin E-13C5,15N. Molecular formula: C34[13C]5H67N4[15]NO7. Mole weight: 723.95. | |
| MMAE-[d8] | MMAE-[d8] is a labelled analogue of MMAE, which is a potent mitotic inhibitor and a tubulin inhibitor. Alternative Names: D8-MMAE; D8-Monomethyl auristatin E. Grades: 98% by HPLC; 98% atom D. CAS No. 2070009-72-0. Molecular formula: C39H59D8N5O7. Mole weight: 726.03. | |
| MMAF | Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. Uses: Adcs cytotoxin. Alternative Names: Monomethylauristatin F; Monomethyl Auristatin F; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; Monomethylauristatin Phenylalanine; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. Grades: ≥98% by HPLC. CAS No. 745017-94-1. Molecular formula: C39H65N5O8. Mole weight: 731.48. | |
| MMAF-OMe | MMAF-Ome is a methoxyl analogue of MMAF, used in antibody-drug conjugates (ADCs) as the antimitotic agent part. The methoxyl works as the reaction group. MMAF is a potent auristatin-derived antineoplastic agent, working by inhibition of tubulin polymerization. It exhibited cytotoxicity in Karpas 299, H3396, 786-O and Caki-1 cells with IC50 values of 119nM, 105nM, 257nM and 200nM after 96-hour treatment. Alternative Names: MMAF-OMe, Monomethyl auristatin F methyl ester; methyl (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoate. CAS No. 863971-12-4. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| Moc-Ile-OH | Moc-Ile-OH. Alternative Names: MeOCO-Ile-OH; Moc Ile OH; N-Methoxycarbonyl-L-isoleucine. CAS No. 74761-39-0. Molecular formula: C8H15NO4. Mole weight: 189.21. | |
| Mogroside V | Mogroside V is extracted from the fruit of Siraitia grosvenorii Swingle. It is 300 times sweeter than cane sugar and low in calories. It had a significant effect on insulin secretion and confirmed that the natural sweetener LHK could be beneficial for use by diabetic populations. Studies have found that mogrosides V have strong sweetness and functional effects. Alternative Names: Momordica Extract; (24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]cucurbit-5-ene-11α,25-diol; (3β,9β,10α,11α,24R)-3-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside; Esgoside. Grades: >98%. CAS No. 88901-36-4. Molecular formula: C60H102O29. Mole weight: 1287.43. | |
| Momordicin IV | Momordicin IV is a natural product found in Momordica charantia (bitter melon). Alternative Names: 19-Norlanosta-5,24-diene-9-carboxaldehyde, 7-(β-D-glucopyranosyloxy)-3,23-dihydroxy-, (3β,7β,9β,10α,24R)-; (3S,7S,8S,9R,10R,13R,14S,17R)-3-hydroxy-17-((2R,4R)-4-hydroxy-6-methylhept-5-en-2-yl)-4,4,13,14-tetramethyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,2,3,4,7,8,10,11,12,13,14,15,16,17-tetradecahydro-9H-cyclopenta[a]phenanthrene-9-carbaldehyde; (3β,7β,9β,10α,24R)-7-(β-D-Glucopyranosyloxy)-3,23-dihydroxy-19-norlanosta-5,24-diene-9-carboxaldehyde; Momordicine IV. Grades: ≥95%. CAS No. 894412-35-2. Molecular formula: C36H58O9. Mole weight: 634.85. | |
| Momordicoside G | Momordicoside G is isolated from the herbs of Mormodica charantia L. Alternative Names: (1R,4S,5S,8R,9R,12S,13S,16S)-8-[(2R,4E)-6-Methoxy-6-methyl-4-hepten-2-yl]-5,9,17,17-tetramethyl-18-oxapentacyclo[10.5.2.01,13.04,12.05,9]nonadec-2-en-16-yl β-D-allopyranoside. Grades: 96%. CAS No. 81371-54-2. Molecular formula: C37H60O8. Mole weight: 632.9. | |
| Momordicoside K | Momordicoside K is a cucurbitacin found in Momordica charantia (bitter melon). Alternative Names: 19-Norlanosta-5,23-diene-9-carboxaldehyde, 7-(β-D-glucopyranosyloxy)-3-hydroxy-25-methoxy-, (3β,7β,9β,10α,23E)-; (1S,4R,7S,9β,23E)-9-Formyl-1-hydroxy-25-methoxy-10,14-dimethyl-4,9-cyclo-9,10-secocholesta-5,23-dien-7-yl β-D-glucopyranoside. Grades: ≥95%. CAS No. 81348-84-7. Molecular formula: C37H60O9. Mole weight: 648.88. | |
| Momordicoside L | Momordicoside L is a cucurbitacin found in Momordica charantia (bitter melon). Alternative Names: 19-Norlanosta-5,23-diene-9-carboxaldehyde, 7-(β-D-glucopyranosyloxy)-3,25-dihydroxy-, (3β,7β,9β,10α,23E)-; (1S,4R,7S,9β,23E)-9-Formyl-1,25-dihydroxy-10,14-dimethyl-4,9-cyclo-9,10-secocholesta-5,23-dien-7-yl β-D-glucopyranoside; (3β,7β,9β,10α,17β)-7-(β-D-glucopyranosyloxy)-3-hydroxy-17-[(3E)-5-hydroxy-1,5-dimethylhex-3-en-1-yl]-4,4,14-trimethylestr-5-ene-9-carboxaldehyde. Grades: ≥95%. CAS No. 81348-83-6. Molecular formula: C36H58O9. Mole weight: 634.85. | |
| Momordin Ic | Momordin Ic, isolated from the fruits of Kochia scoparia (L.) Schrad, induced apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Thus, Momordin Ic might represent a potential source of anticancer candidate. Momordin Ic and oleanolic acid obtained from KF appear to contribute to alleviating the adverse effects of CCl4 treatment by enhancing the hepatic antioxidant defense system. What's more, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), possibly 5-HT(2C) and/or 5-HT(2B) receptors, which, in turn, increases synthesis of prostaglandins. Uses: Antibacterial. Alternative Names: (3b)-17-Carboxy-28-norolean-12-en-3-yl 3-O-(b-D-xylopyranosyl)-b-D-glucuronide; (3β)-17-Carboxy-28-norolean-12-en-3-yl 3-O-β-D-xylopyranosyl-β-D-glucopyranosiduronic acid; Mormordin Ic. Grades: >98%. CAS No. 96990-18-0. Molecular formula: C41H64O13. Mole weight: 764.94. | |
| Monensin A | Monensin A is an oxygen-containing heterocyclic polyether antibiotic produced by Str. cinnamonensis. It has antibacterial, mycobacterial, fungal and protozoan activity, but it has a weaker effect on gram-negative bacteria and has an inhibitory effect on HeLa cells. Alternative Names: Monensic acid; monensin; Monensina; Monensinum. Grades: >95% by HPLC. CAS No. 17090-79-8. Molecular formula: C36H62O11. Mole weight: 670.87. | |
| Monensin sodium salt | Sodium Monensin, isolated from Streptomyces cinnamonensis, is a well-known representative of naturally polyether ionophore antibiotics. It is widely used in ruminant animal feeds. Alternative Names: Monensin A sodium salt; 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid, monosodium salt; A 3823A; Coban; Rumensin; NSC 343257. Grades: >98%. CAS No. 22373-78-0. Molecular formula: C36H61NaO11. Mole weight: 692.85. | |
| Mono-2-ethylhexyl phthalate-[d4] | Mono-2-ethylhexyl phthalate-[d4] is the labelled analogue of Monoethylhexyl phthalic acid (MEHP). MEHP is an active metabolite of Bis(2-ethylhexyl)phthalate (DEHP). Alternative Names: Mono-2-ethylhexyl phthalate-D4; Mono(2-ethylhexyl) Phthalate-d4; 2-Ethylhexyl Hydrogen Phthalate-d4; Phthalic Acid-d4 Mono(2-ethylhexyl) Ester; 1,2-(Benzene-d4)dicarboxylic Acid Mono(2-ethylhexyl) Ester; MEHP-d4; rac Mono(ethylhexyl) Phthalate-d4. Grades: 95% by HPLC; 98% atom D. CAS No. 1276197-22-8. Molecular formula: C16H18D4O4. Mole weight: 282.37. | |
| Monobenzone | Monobenzone is a topical agent for medical depigmentation. Alternative Names: 4-(Benzyloxy)phenol; Hydroquinone monobenzyl ether. Grades: 98.0%. CAS No. 103-16-2. Molecular formula: C13H12O2. Mole weight: 200.23. | |
| Monobenzyl Phthalate-[d4] | N-Benzoylglycine, also known as Hippuric Acid, is the glycine conjugate of benzoic acid commonly found in ruminant urine. Hippuric acid is synthesized in the liver and its production is greatly increased following consumption of benzoic acid. In itself it does not have a direct biological function, however p-hydroxy-hippurica acid can be used as an inhibitor of Ca2+ ATPase. A possible biomarker of Parkinson's disease. Uses: N-benzoylglycine also known as hippuric acid is the glycine conjugate of benzoic acid commonly found in ruminant urine. it is synthesized in the liver and its production is greatly increased following consuption of benzoic acid. in itself it does not have. Alternative Names: Monobenzyl Phthalate D4; 2-[(Benzyloxy)carbonyl](2H4)benzoic acid. Grades: 98% atom D. CAS No. 478954-83-5. Molecular formula: C15H8D4O4. Mole weight: 260.28. | |
| Monobutyl Phthalate-[d4] | Monobutyl Phthalate-[d4]. Uses: Labelled di-n-butylphthalate (dbp) metabolite. Alternative Names: Monobutyl Phthalate D4; 2-(Butoxycarbonyl)(2H4)benzoic acid. Grades: 99% atom D. CAS No. 478954-81-3. Molecular formula: C12H10D4O4. Mole weight: 226.26. | |
| Monomethyl fumarate-[d5] | Monomethyl fumarate-[d5] is labelled Monomethyl fumarate. Monomethyl Fumarate is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. It is potent nicotinic acid receptor agonist. Alternative Names: Monomethyl fumarate d5; (2E)-2-Butenedioic Acid 1-Methyl Ester-d5. Grades: 95% by HPLC; 95% atom D. CAS No. 1616345-45-9. Molecular formula: C5HD5O4. Mole weight: 135.13. | |
| Mono-methyl terephthalate | Mono-methyl terephthalate is used in the synthesis of Hepatits C antiviral activity. Also used in the design and preparation of benzamide derivatives as BRAFV600E inhibitors, which if mutated, can influence malignancies and melanomas. Uses: Mono-methyl terephthalate is used in the synthesis of hepatits c antiviral activity. also used in the design and preparation of benzamide derivatives as brafv600e inhibitors, which if mutated, can influence malignancies and melanomas. Alternative Names: MMT; 1,4-Benzenedicarboxylic Acid Monomethyl Ester; Terephthalic Acid Monomethyl Ester; 4-(Carbomethoxy)benzoic Acid; 4-(Methoxycarbonyl)benzoic Acid; 4-[(Methyloxy)carbonyl]benzoic Acid; Hydrogen Methyl Terephthalate; Methyl 4-Carboxybenzoate; Methyl Hydrogen Terephthalate; Methyl p-Carboxybenzoate; Methyl p-Phthalate; Monomethyl terephthalate; NSC 210838; p-(Methoxycarbonyl)benzoic Acid; p-Carbomethoxybenzoic Acid. Grades: 99 % (HPLC). CAS No. 1679-64-7. Molecular formula: C9H8O4. Mole weight: 180.16. | |
| Monorden A | Monorden A is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity. It inhibits Hsp90 activity by binding to the ATP-binding pocket, thus suppressing cell transformation induced by src, ras and mos. Alternative Names: radicicol. Grades: >98%. CAS No. 12772-57-5. Molecular formula: C18H17ClO6. Mole weight: 364.78. | |
| Morantel (+)-tartrate salt | Morantel tartrate, the 3-methyl thiophene tartrate salt analog of pyrantel tartrate, is a low toxic broad spectrum anthelmintic that is effective against the immature and adult stages of certain species of nematodes. Alternative Names: 2,3-dihydroxybutanedioic acid. Grades: >98%. CAS No. 26155-31-7. Molecular formula: C16H22N2O6S. Mole weight: 370.42. | |
| Moricin | Moricin is a novel antibacterial peptide that shows antibacterial activity against Staphylococcus aureus and it was isolated from the hemolymph of the silkworm, Bombyx mori. The peptide showed antibacterial activity against several Gram-negative and -positive bacteria and had a higher activity against Gram-positive bacteria than cecropin B1, a major antibacterial peptide of B. mori. Alternative Names: Moricin-1; Moricin-2. | |
| Moringa extract | Moringa extract. Alternative Names: Leaves of Moringa oleifera Extract;Spicy leaves extract. | |
| Moringin | Moringin is a natural compound isolated from the seeds of Moringa oleifera. Moringin is a potent and selective TRPA1 ion channel agonist with an EC50 of 3.14 μM. Alternative Names: 4-(α-L-Rhamnosyloxy)benzyl isothiocyanate. Grades: 95.0%. CAS No. 73255-40-0. Molecular formula: C14H17NO5S. Mole weight: 311.35. | |
| Moronic acid | Moronic acid isolated from the herbs of Rhus chinensis. It shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. Uses: Anti-hiv;anti-hsv;anti-ebv. Alternative Names: Moronic acid;6713-27-5;3-Oxoolean-18-en-28-oic acid;(4aS,6aR,6aR,6bR,8aR,12aR,14aS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-4,5,6,6a,7,8,8a,11,12,13,14,14a-dodecahydro-3H-picene-4a-carboxylic acid;XW8W7HC4JK;MLS000563430;CHEBI:30815;Moronicacid;SMR000232278;AMBRONIC ACID;UNII-XW8W7HC4JK;(+)-MORONIC ACID;MLS000728508;SCHEMBL324972;3-Oxoolean-18-en-28-oic acid; (+)-Moronic acid; Ambronic acid;CHEMBL472. Grades: 98%. CAS No. 6713-27-5. Molecular formula: C30H46O3. Mole weight: 454.68. | |
| Morusin | Morusin is a prenylated flavonoid isolated from the root bark of Morus alba L. It exhibits antioxidant and anti-inflammatory activity. Uses: Antinociceptive; anti-oxidant and anti-inflammatory effects. Alternative Names: 2-(2,4-Dihydroxyphenyl)-3-(3-methyl-2-butenyl)-5-hydroxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one. Grades: 97%. CAS No. 62596-29-6. Molecular formula: C25H24O6. Mole weight: 420.5. | |
| Moxidectin | Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. Moxidectin can be used to prevent heartworm infection in dogs. Moxidectin is a semisynthetic derivative of nemadectin which is produced by fermentation by Streptomyces cyano-griseus. Uses: Insecticides. Alternative Names: ProHeart 6; CL301423; CL-301423; CL 301423; Cydectin; milbemectin; milbemycin; Milbemycin B. Grades: >98%. CAS No. 113507-06-5. Molecular formula: C37H53NO8. Mole weight: 639.82. | |
| MPB-MMAF | MPB-MMAF is a drug-linker conjugate for ADC by using Monomethylauristatin F (MMAF,a potent tubulin polymerization inhibitor), linked via MPB. Molecular formula: C53H76N6O11. Mole weight: 973.22. | |
| m-PEG4-COOH | m-PEG4-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: m-PEG3-CH2CH2COOH; 2,5,8,11-Tetraoxatetradecan-14-oic acid; m-PEG4-Acid; 4,7,10,13-Tetraoxatetradecanoic acid; 2,5,8,11-Tetraoxa-14-tetradecanoic Acid; mPEG3-propionic acid; COOHCH2CH2-PEG3-OME. Grades: ≥95%. CAS No. 67319-28-2. Molecular formula: C10H20O6. Mole weight: 236.26. | |
| m-PEG7-Ms | m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: 2,5,8,11,14,17,20-heptaoxadocosan-22-yl methanesulfonate; 2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate. Grades: ≥95%. CAS No. 477775-57-8. Molecular formula: C16H34O10S. Mole weight: 418.50. | |
| mPEG8-amine | m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: m-PEG8-amine; 2,5,8,11,14,17,20,23-Octaoxapentacosan-25-amine; mPEG8-NH2; 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine; 3,6,9,12,15,18,21,24-octaoxa-pentacosylamine; methyl-PEG8-amine. Grades: ≥95%. CAS No. 869718-81-0. Molecular formula: C17H37NO8. Mole weight: 383.48. | |
| m-PEG8-COOH | m-PEG8-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: mPEG7-propionic acid; m-PEG8-acid; 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid; mPEG7-CH2CH2COOH; 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid; MPEG7-OCH2CH2COOH. Grades: ≥95%. CAS No. 1093647-41-6. Molecular formula: C18H36O10. Mole weight: 412.47. | |
| MS-444 | MS-444, originally isolated from Micromonospora sp. KY7123, is a myosin light chain kinase (MLCK) inhibitor. Alternative Names: 5,8-Dihydroxy-3-methyl-4-(9H)-naphtho(2,3-c)furanone; MS 444; 5,8-dihydroxy-3-methyl-9H-benzo[f][2]benzofuran-4-one. CAS No. 150045-18-4. Molecular formula: C13H10O4. Mole weight: 230.22. | |
| mu-conotoxin | mu-conotoxin. Grades: 96%. CAS No. 936616-33-0. Molecular formula: C92H139N35O28S6. Mole weight: 2375.7. | |
| μ-Conotoxin GIIIA | μ-Conotoxin GIIIA, originally isolated from the venom of the marine snail Conus geographus L, blocks sodium channels of muscle subtypes with very high selectivity. Alternative Names: L-arginyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4R)-4-hydroxy-L-prolyl-L-lysyl-L-lysyl-L-cysteinyl-L-lysyl-L-alpha-aspartyl-L-arginyl-L-glutaminyl-L-cysteinyl-L-lysyl-(4R)-4-hydroxy-L-prolyl-L-glutaminyl-L-arginyl-L-cysteinyl-L-cysteinyl-L-alaninamide (3->15),(4->20),(10->21)-tris(disulfide); H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Lys-Lys-Cys-Lys-Asp-Arg-Gln-Cys-Lys-Hyp-Gln-Arg-Cys-Cys-Ala-NH2 (Disulfide bridge: Cys3-Cys15, Cys4-Cys20, Cys10-Cys21); Geographutoxin I; mu-conotoxin GIIIA. Grades: 95%. CAS No. 129129-65-3. Molecular formula: C100H170N38O32S6. Mole weight: 2609.08. | |
| Mulberroside A | Mulberroside A is a natural compound extracted from the root bark of white mulberry. Mulberroside A treatment could down-regulate P-gp expression and function accompanied by the activation of PKC and NF-κB, and this should be taken into consideration in potential herb-drug interactions when Mulberroside A or M. alba are co-administered with other drugs transported by P-gp. Alternative Names: 3-{(E)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl}-5-hydroxyphenyl beta-D-glucopyranoside. Grades: >98%. CAS No. 102841-42-9. Molecular formula: C26H32O14. Mole weight: 568.53. | |
| Mupirocin | Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections. Alternative Names: (2E)-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid 8-Carboxyoctyl Ester; BRL 4910A; Bactoderm; Bactroban; Bactroban Ointment; Mupirocin Neo-Sensitabs; Pseudomonic Acid; Pseudomonic Acid A; Turixin; trans-Pseudomonic Acid. Grades: Assay: 920 μg/mg - 1020 μg/mg. CAS No. 12650-69-0. Molecular formula: C26H44O9. Mole weight: 500.62. | |
| Mupirocin Calcium Salt Dihydrate | A carboxylic acid bacteriostatic / bactericidal antibiotic. Mupirocin Calcium Salt sodium is a calcium salt of Mupirocin, which is a carboxylic acid bacteriostatic / bactericidal antibiotic. Uses: Protein synthesis inhibitors. Alternative Names: [2E,8[2S,3S(1S,2S)]]-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-L-talo-Non-2-enonic Acid 8-Carboxyoctyl Ester Calcium Salt Dihydrate; Calcium Mupirocin Dihydrate; Mupirocin Calcium Hydrate. Grades: 98%. CAS No. 115074-43-6. Molecular formula: C26H44O9.1/2Ca.H2O. Mole weight: 538.68. | |
| Murepavadin | Murepavadin is a Pseudomonas specific peptidomimetic antibiotic. CAS No. 944252-63-5. Molecular formula: C73H112N22O16. Mole weight: 1553.8. | |
| (±)-Muscarine chloride | (±)-Muscarine chloride is a muscarinic acteylcholine receptor agonist which was originally isolated from Amanita muscaria. Alternative Names: DL-Muscarin Chloride; DL-Muscarine Chloride; 2,5-Anhydro-1,3,6-trideoxy-1-(trimethylammonio)-ribo-hexitol Chloride; (2α,4β,5α)-(±)-Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanaminium Chloride. Grades: 95%. CAS No. 2936-25-6. Molecular formula: C9H20ClNO2. Mole weight: 209.71. | |
| Mutacin IV | Mutacin IV is an antimicrobial peptide found in Streptococcus mutans UA140, and has antibacterial activity. Mutacin IV is a nonlantibiotic bacteriocin encoded by the nlm operon, which contains two genes, nlmA and nlmB, organized in tandem. Alternative Names: NlmA and NlmB. Grades: >98%. | |
| Mutanolysin | Mutanolysin is an N-acetylmuramidase from Streptomyces globisporus. Mutanolysin lyses Listeria and other Gram-positive bacteria such as Lactobacillus and Lactococcus. Mutanolysin has been used in a study to assess lysing and generating protoplasts of dairy streptococci, and also to investigate the conversion of group B streptococci to protoplasts. It provides gentle cell lysis for the isolation of readily degradable biomolecules and RNA from bacteria. It has been used to form spheroplasts for isolation of DNA. Alternative Names: Mutanolysin from Streptomyces globisporus. CAS No. 55466-22-3. Mole weight: 23kD. | |
| Mutilin | Mutilin, is used to perform biological studies with focus on antimicrobial activity. It is a minor metabolite of the pleuromutilin family isolated from pleurotus mutilus. Alternative Names: [3aS-(3aα,4β,5α,6α,8β,9α,9aβ,10S*)]-6-Ethenyloctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one; (+)-Mutilin; (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyloctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one. Grades: >99% by HPLC. CAS No. 6040-37-5. Molecular formula: C20H32O3. Mole weight: 320.47. | |
| m-Xylene-[dimethyl-d6] | m-Xylene-[dimethyl-d6]. Alternative Names: 1,3-Dimethyl-d6-benzene. Grades: 99% by CP; 98% atom D. CAS No. 29636-65-5. Molecular formula: C8H4D6. Mole weight: 112.20. | |
| Mycophenolate Mofetil | Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Uses: Anti-inflammatory agents, non-steroidal, antineoplastic agents, dermatologic agents, enzyme inhibitors, immunosuppressive agents. Alternative Names: TM-MMF; Myfenax; Mycophenolic acid morpholinoethyl ester; Mycophenolatemofetil; (E)-2-Morpholinoethyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate. Grades: >98%. CAS No. 128794-94-5. Molecular formula: C23H31NO7. Mole weight: 433.49. | |
| Mycophenolic Acid | Mycophenolic acid is a small lactone antibiotic produced by Pen. brevicom pactum and Pen. stoloniferum. Activity against gram-positive bacteria. In animal experiments, it has inhibitory effect on sarcoma-180, Lewis lung cancer, adenocarcinoma Ca-755, Walker tumor 256, Yoshida sarcoma, Freund ascites tumor, etc. Mycophenolic acid is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation. It inhibits an enzyme needed for the growth of T cells and B cells. Uses: Antibiotics, antineoplastic. Alternative Names: Mycophenolate; Melbex; Myfortic; (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid; (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid. Grades: >98%. CAS No. 24280-93-1. Molecular formula: C17H20O6. Mole weight: 320.34. | |
| Myelin Basic Protein MBP | Myelin basic protein MBP is the second most abundant protein in the central nervous system myelin and is responsible for the adhesion of the cytosolic surfaces of multilayered compact myelin. Alternative Names: Myelin Basic Protein (4-14); MBP(4-14) bovine; Myelin Basic Protein Fragment 4-14; L-Leucine, L-glutaminyl-L-Lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-; H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH; Myelin basic protein (4-14), N-acetylated. Grades: ≥95%. CAS No. 126768-94-3. Molecular formula: C60H103N21O17. Mole weight: 1390.59. | |
| Myelin Oligodendrocyte Glycoprotein (35-55) (human) | Myelin Oligodendrocyte Glycoprotein (35-55) (human) is a myelin component of the central nervous system that has immunogenicity but no encephalogenicity, and partially cross-reacts with mMOG35-55. Alternative Names: MOG (35-55) (human); H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH; L-methionyl-L-alpha-glutamyl-L-valyl-glycyl-L-tryptophyl-L-tyrosyl-L-arginyl-L-prolyl-L-prolyl-L-phenylalanyl-L-seryl-L-arginyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-tyrosyl-L-arginyl-L-asparagyl-glycyl-L-lysine. Grades: ≥95% by HPLC. CAS No. 163158-19-8. Molecular formula: C120H179N35O28S. Mole weight: 2591.99. | |
| myo-Inositol-[1,2,3,4,5,6-d6] | A labelled inositol. The structural basis of many signaling and secondary messenger molecules includes: insulin signal transduction, cytoskeletal assembly, nerve guidance, membrane potential, serotonin activity, and lipolysis and cholesterol reduction. Alternative Names: myo-Inositol-1,2,3,4,5,6-d6; (2H6)Cyclohexane-1,2,3,4,5,6-hexol; myo-Inositol-C-d6; Cyclohexitol-d6; Dambose-d6; Inosital-d6; Inosite-d6; Inositene-d6; Inositina-d6; Inositol-d6; Mesoinosite-d6; Mesoinositol-d6; Mesol-d6; Mesovit-d6; Myoinosite-d6; Nucite-d6; Phaseomannite-d6; Phaseomannitol-d6; Scyllite-d6; cis-1,2,3,5-trans-4,6-Cyclohexanehexol-d6; 1,2,3,4,5,6-Cyclohexane-d6-hexol, (1α,2α,3α,4β,5α,6β)-. Grades: 98% by CP; 98% atom D. CAS No. 68922-44-1. Molecular formula: C6H6D6O6. Mole weight: 186.19. | |
| Myosmine-[2,4,5,6-d4] | Myosmine-[2,4,5,6-d4]. Alternative Names: Myosmine-2,4,5,6-D4. Grades: 98% atom D. CAS No. 66148-17-2. Molecular formula: C9H6D4N2. Mole weight: 150.21. | |
| Myrcludex B | Myrcludex B is a drug candidate for the treatment of hepatitis B and D. It is under a phase II clinical trial. Myrcludex B acts by inhibiting the sodium taurocholate cotransporting polypeptide. Alternative Names: MyrB; Myrcludex-B; Hepatera; MYR Pharma; Vision7; Bulevirtide. Grades: ≥98%. CAS No. 2012558-47-1. Molecular formula: C248H355N65O72. Mole weight: 5398.95. | |
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