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Serotonin-[d4]
Serotonin-[d4] is the labelled analogue of serotonin. Serotonin is a monoamine neurotransmitter and popularly thought to be a contributor to feelings of well-being and happiness. Alternative Names: Serotonin D4. Grades: 95% by HPLC; 95% atom D. CAS No. 58264-95-2. Molecular formula: C10H8D4N2O. Mole weight: 180.24.
Ser-Pro
Ser-Pro is a substrate for skin fibroblast prolidase. Alternative Names: L-Proline, L-seryl-; serylproline; L-seryl-L-proline; (S)-1-((S)-2-Amino-3-hydroxypropanoyl)pyrrolidine-2-carboxylic acid; S-P Dipeptide; Serine Proline dipeptide. CAS No. 23827-93-2. Molecular formula: C8H14 N2 O4. Mole weight: 202.21.
Sertraline-[d3] Hydrochloride
Isotopic labelled sertraline hydrochloride. Sertraline hydrochloride is a selective serotonin reuptake inhibitor (SSRI) for the treatment of depression. Alternative Names: 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine-d3 Hydrochloride; rac Sertraline-d3 Hydrochloride. Grades: > 95%. CAS No. 1217741-83-7. Molecular formula: C17H15D3Cl3N. Mole weight: 345.71.
Setmelanotide
Setmelanotide is a melanocortin 4 receptor (MC4R) agonist (EC50 = 0.27 nM for human MC4R) that is used as a peptide drug and investigational anti-obesity medication. Alternative Names: RM-493; BIM-22493; IRC-022493. CAS No. 920014-72-8. Molecular formula: C49H68N18O9S2. Mole weight: 1117.31.
Setomimycin
It is produced by the strain of Str. pseudovenezuelae AM-2947. It has anti-gram-positive bacteria and mycobacteria effects, and has the effect of inhibiting sarcoma-180. Alternative Names: Setomimycin;69431-87-4;Antibiotic AM 2947;AM-2947;4-acetyl-10-(1-acetyl-2,5,10-trihydroxy-2-methyl-4-oxo-1,3-dihydroanthracen-9-yl)-8,9-dihydroxy-3-methyl-4H-anthracen-1-one;AM 2947;1,1'-Diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl[9,9'-bianthracene]-4,4'(1H,1'H)-dione;72484-73-2;Antibiotic A 39183B;BRN 5202658;Setomimicin;DTXSID40989284;CHEBI:223714;AKOS040747478;(9,9'-Bianthracene)-4,4'(1H,1'H)-dione, 1,1'-diacetyl-2,3-dihydro-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl-;(9,9'-Bianthracene)-4,4'(1H,1'H)-dione, 2,3-dihydro-1,1'-diacetyl-2,2'-dimethyl-2,5,5',10,10'-pentahydroxy-;HY-124439;CS-0086470;1,1'-diacetyl-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl-2,3-dihydro-[9,9'-bianthracene]-4,4'(1h,1'h)-dione;1,1'-Diacetyl-2,5,5',10,10'-pentahydroxy-2,2'-dimethyl-2,3-dihydro[9,9'-bianthracene]-4,4'(1H,1'H)-dione. Grades: >95% by HPLC. CAS No. 69431-87-4. Molecular formula: C17H16F6N2O. Mole weight: 378.31.
(S)-Fmoc-2,6-Difluorotyrosine
(S)-Fmoc-2,6-Difluorotyrosine. CAS No. 273221-87-7. Molecular formula: C24H19F2NO5. Mole weight: 439.41.
(S)-Fmoc-Meta-Tyrosine O-Tert-Butyl Ether
(S)-Fmoc-Meta-Tyrosine O-Tert-Butyl Ether. Alternative Names: (S)-N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-meta-tyrosine; Fmoc-L-m-Tyrosine(tBu)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-(tert-butoxy)phenyl)propanoic acid. CAS No. 204384-71-4. Molecular formula: C28H29NO5. Mole weight: 459.5.
Shikimic acid
Shikimic acid(Shikimate), more commonly known as its anionic form shikimate, is an important biochemical intermediate in plants and microorganisms. Alternative Names: shikimate; (-)-Shikimic acid; 3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid. Grades: >98%. CAS No. 138-59-0. Molecular formula: C7H10O5. Mole weight: 174.15.
Shinorine
Shinorine, a mycosporine-like amino acid (MAA) and an analog of porphyra-344, is a small molecule sunscreen produced by some bacteria with antioxidant, anti-UV, and sun protection properties. Shinorine ameliorates chromium-induced toxicity in zebrafish hepatocytes through facultatively activating the Nrf2-Keap1-ARE pathway. Both porphyrin-334 and Shinorine antioxidants and direct antagonists of Keap1-Nrf2 binding. Shinorine may be an effective drug to prevent or delay the progression of a variety of degenerative aging diseases. Alternative Names: L-Serine, N-[3-[(carboxymethyl)amino]-5-hydroxy-5-(hydroxymethyl)-2-methoxy-2-cyclohexen-1-ylidene]-; demethyl-analog of Porphyra 334; N-[3-[(Carboxymethyl)amino]-5-hydroxy-5-(hydroxymethyl)-2-methoxy-2-cyclohexen-1-ylidene]-L-serine. Grades: ≥95%. CAS No. 73112-73-9. Molecular formula: C13H20N2O8. Mole weight: 332.31.
Showdomycin
Showdomycin is a nucleoside antibiotic produced by the strain of Str. showdoensis Z-452. It has anti-bacterial effect. 5-15 mg/(kg.d) of Showdomycin can inhibit Ehrlich ascites cancer. It is also cytotoxic to HeLa cells. Uses: Antibiotics, antineoplastic. Alternative Names: D-Showdomycin; 2-beta-D-Ribofuranosylmaleimide; NSC 93047; 3-beta-D-Ribofuranosyl-1H-pyrrole-2,5-dione; Maleimide, 2-b-D-ribofuranosyl-; (+)-Showdomycin; D-(+)-Showdomycin. Grades: ≥ 97%. CAS No. 16755-07-0. Molecular formula: C9H11NO6. Mole weight: 229.19.
Sibiromycin
It is an aminoglycoside antibiotic produced by the strain of Streptosporangium sibiricum. It has anti-bacterial effect and has an inhibitory effect on reticuloendothelial sarcoma RAB-1 and oncogenic AK/LY cells. Two times of the maximum tolerated dose of intravenous administration can inhibit OZH-5 tumor and lymphosarcoma Lic-1. It has very high DNA binding affinity and cytotoxicity against cancer cell lines. Alternative Names: Sybiromycin; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 7-((4,6-dideoxy-3-C-methyl-4-(methylamino)-alpha-L-mannopyranosyl)oxy)-1,10,11,11a-treahydro-9,11-dihydroxy-8-methyl-2-(1E)-1-propenyl-, (11R,11aS)-. CAS No. 12684-33-2. Molecular formula: C24H33N3O7. Mole weight: 475.54.
Sieber Amide Resin
Sieber amide resin has been developed for the Fmoc-SPPS of fully t-butyl protected peptide amides. Alternative Names: Xanthenyl linker resin. Grades: 100-200 mesh,1% DVB,0.3-0.8mmol/g. Molecular formula: C36H29NO4. Mole weight: 539.20965841.
Silodosin
Silodosin shows high selectivity for the alpha(1A)-AR subtype. Alternative Names: KMD-3213; KMD3213; KMD 3213; KAD 3213; KAD 3213; KAD3213; Silodosin. trade names Rapaflo, Silodyx, Rapilif, Silodal, Urief, Urorec. Grades: >98%. CAS No. 160970-54-7. Molecular formula: C25H32F3N3O4. Mole weight: 495.53.
(±)-Silybin is a flavonolignan isolated from milk thistle, Silybum marianum. It exhibits antioxidant and antineoplastic activities. Alternative Names: 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-rel-; rel-(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one. Grades: ≥95%. CAS No. 36804-17-8. Molecular formula: C25H22O10. Mole weight: 482.44.
Silybin A
Silymarin, isolated from the herb of Silybum marianum (L.) Gaertn, is an antioxidant or free radical scavenger. Silymarin and Prunella vulgaris improve antioxidant status in blood and liver, and positively affect plasma lipoprotein profile in an experimental model of dietary induced hypertriglyceridemia. Both in vitro and animal research suggest that Silymarin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silymarin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells. Silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. Treatment with silymarin may reduce the lipoperoxidation of cell membranes and insulin resistance, significantly decreasing endogenous insulin overproduction and the need for exogenous insulin administration. Silybin is a natural compound also can be used in cosmetics material. Uses: Protective agents. Alternative Names: Silybin; 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-; (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3
Simvastatin
Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM. Alternative Names: Nodinitib-1; Zocor; Synvinolin; MK-733; Sinvacor; MK 733; MK733. Grades: >98%. CAS No. 79902-63-9. Molecular formula: C25H38O5. Mole weight: 418.57.
Simvastatin-[d3]
An isotope labelled of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Alternative Names: Simvastatin D3 lactone. Grades: 95% by HPLC; 98% atom D. CAS No. 1002347-61-6. Molecular formula: C25H35D3O5. Mole weight: 421.58.
Sinapic acid
Sinapic acid also called as 4-Hydroxy-3,5-dimethoxycinnamic acid, is a natural phenylpropanoid compound isolated from the leaves of Platycladus orientalis. Sinapic acid exhibits the antibacterial and antioxidant activities. Uses: Antibacterial, antioxidant. Alternative Names: (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid. Grades: > 98 %. CAS No. 530-59-6. Molecular formula: C11H12O5. Mole weight: 224.21.
Sinapultide
Sinapultide is a synthetic protein that mimics human lung surfactant protein B. This compound is undergoing preclinical development in lung disorders, and is planned for a phase III clinical trial for aerosol delivery system (ADS) in Respiratory distress syndrome. Alternative Names: KL4 peptide. Grades: >95%. CAS No. 138531-07-4. Molecular formula: C126H238N26O22. Mole weight: 2469.45.
Sinensetin
Sinensetin is a natural flavonoid compound isolated from the fruit of Citrus aurantium L. Sinensetin exhibits the anti-inflammatory, antimutagenic and anticancer activities. Uses: Antimutagenic, anticancer, anti-inflammatory. Alternative Names: 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one;Pedalitin permethyl ether;Sinenstein;2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-chromone. Grades: >98%. CAS No. 2306-27-6. Molecular formula: C20H20O7. Mole weight: 372.369.
Sinomenine
Sinomenine, a pure alkaloid extracted from the chinese medical plant Sinomenium acutum, is used for the treatment of rheumatism and arthritis. Uses: Antirheumatic agents. Alternative Names: Cucoline, Kukoline; 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-morphinan-6-one. Grades: >98%. CAS No. 115-53-7. Molecular formula: C19H23NO4. Mole weight: 329.39.
Sinomenine hydrochloride
Sinomenine HCl could improve survival, reduce organ damage, and attenuate the release of inflammatory cytokines induced by CLP, at least in part through regulating autophagy activities. Uses: Anti-tumor and anti-metastasis. Alternative Names: SINOMENINE HYDROCHLORIDE; SINOMENINE HCL; Tuduranine Hydrochloride; (9α,13α,14α)- 7,8-Didehydro-4- hydroxy-3,7-diMet; 7,8-Didehydro-4-hydroxy-3,7-diMethoxy-17-Methyl- 9α,13α,14α-Morphinan-6-one Hydrochloride. Grades: >98%. CAS No. 6080-33-7. Molecular formula: C19H23NO4.HCl. Mole weight: 365.85.
Sirtratumab vedotin
Sirtratumab vedotin is an antibody-drug conjugate consisting of a SLITRK6-specific human antibody conjugated to MMAE via a protease-cleavable linker. Sirtratumab vedotin has the potential for the treatment of advanced urothelial cancer. Alternative Names: ASG-15ME; AGS15E. CAS No. 1824663-83-3.
Sisomicin
It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa. It has no cross-resistance to kanamycin, but has cross-resistance to gentamycin. 50 mg/kg of Sisomicin has protective effect on mice infected with Rickettsia spinosa. Uses: Protein synthesis inhibitors. Alternative Names: D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-; Antibiotic 6640; SCH 13475; Rickamicin; Sisomycin; Sissomicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-D-streptamine; Antibiotic 66-40; BactoCeaze; Ensamycin; Sch 13475; Siseptin. Grades: ≥98%. CAS No. 32385-11-8. Molecular formula: C19H37N5O7. Mole weight: 447.53.
Sitagliptin
Sitagliptin (MK 0431) is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. Sitagliptin is used as a hypoglycemic agent to treat type 2 diabetes. Uses: The treatment of type 2 diabetes. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; MK0431; Xelevia; Januvia; Tesavel; NSC813215; (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone; 1,2,4-triazolo[4,3-a]pyrazine-7(8H)-propanamine, 5,6-dihydro-γ-oxo-3-(trifluoromethyl)-α-[(2,4,5-trifluorophenyl)methyl]-, (αR)-. Grades: >98%. CAS No. 486460-32-6. Molecular formula: C16H15N5OF6. Mole weight: 407.31.
Sitagliptin Impurity 19
Sitagliptin Impurity 19 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: (R)-Sitagliptin N-Boc-Acid Impurity; (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid; Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid. Grades: >95%. CAS No. 486460-00-8. Molecular formula: C15H18F3NO4. Mole weight: 333.3.
Sitosterol-[d7]
Sitosterol-[d7] is the labelled analogue of Sitosterol, a common sterol in plants isolated from wheat germ oil, corn oil. Sitosterol is an antilipemic drug and is used in the treatment of prostatic adenoma. Alternative Names: (24-ethyl)-heptadeuteriostigmast-5-en-3β-ol; Sitosterol-25,26,26,26,27,27,27-D7; 24(R,S)-Stigmast-5-en-3β-ol-d7; Sitosterol-d7; 5-Cholesten-24(RS)-ethyl-3β-ol-25,26,26,26,27,27,27-d7; Cupreol-d7; Azuprostat-d7; 22,23-Dihydrostigmasterol-d7; Quebrachol-d7; Triastonal-d7; β-Sitosterol-d7 (mixture of diasteromers); beta-Sitosterin-d7. Grades: 98%; ≥98% atom D. CAS No. 2260669-28-9. Molecular formula: C29H43D7O. Mole weight: 421.75.
Skullcapflavone I
Skullcapflavone I is a natural flavonoid found in the roots of Scutellaria baicalensis Georgi. Skullcapflavone I has anti-inflammatory and anti-allergic potential. Uses: Anti-inflammatory, anti-allergic. Alternative Names: 5,2'-Dihydroxy-7,8-dimethoxyflavone;5-Hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxy-4H-1-benzopyran-4-one;Panicolin;Skullcapflavon I;2',5-Dihydroxy-7,8-dimethoxyflavone. Grades: >97%. CAS No. 41060-16-6. Molecular formula: C17H14O6. Mole weight: 314.3.
SMCC
SMCC is a heterobifunctional protein crosslinker for antibody-drug-conjugation (ADC). Alternative Names: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid N-Hydroxysuccinimide Ester; NSC 344483; N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate; Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-; 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate; 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylmethyl)-cyclohexanecarboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester; N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate; N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate; Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate; Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate; Succinimidyl 4-[maleimidomethyl]cyclohexan-1-carboxylate. Grades: ≥95%. CAS No. 64987-85-5. Molecular formula: C16H18N2O6. Mole weight: 334.32.
S-Methyl-L-cysteine, a theurapeutic for neurodegenerative diseases, is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Alternative Names: S-Methyl-L-cysteine; NSC 15387; NSC15387; NSC-15387; (2R)-2-amino-3-methylsulfanylpropanoic acid; S-11C-methyl-L-cysteine; S-methylcysteine; S-methylcysteine, (DL-Cys)-isomer; S-methylcysteine, (L-Cys)-isomer; S-methylcysteine, hydrochloride, (L-Cys)-isomer. Grades: 98%. CAS No. 1187-84-4. Molecular formula: C4H9NO2S. Mole weight: 135.18.
SN-38-[d3]
SN-38-[d3] is a labelled analogue of SN-38. SN-38 is the active metabolite of irinotecan. Uses: Labelled sn-38, a metabolite of irinotecan, a dna topoisomerase inhibitor. Alternative Names: SN-38 D3. Grades: 95% atom D. CAS No. 718612-49-8. Molecular formula: C22H17D3N2O5. Mole weight: 395.42.
SNAP-8
SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation and preventing the formation of lines and wrinkles. SNAP-8, which connects two amino acids to the sequence of acetyl-hexapeptide-8, is an upgraded version of hexapeptide. A cosmetic formulation acts as an anti-wrinkle ingredient used in anti-aging products. Alternative Names: N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-α-asparagine; Acetyl octapeptide 1; Acetyl octopeptide 3; Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2. Grades: >98%. CAS No. 868844-74-0. Molecular formula: C41H70N16O16S. Mole weight: 1075.16.
sn-Glycero-3-phosphocholine
sn-Glycero-3-phosphocholine is a nootropic phospholipid and acts as a precursor to choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. Nutritional supplement in health care products. Uses: Ingredient of health care products. Alternative Names: Choline alfoscerate; (R)-2-[[(2,3-Dihydroxypropoxy)hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium Inner Salt; 2-[[[(2R)-2,3-Dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium Inner Salt; Brezal; Cereton; Cholicerin; Cholitiline; Delecit; Glycerylphosphocholine; L-α-GPC; L-α-Glycerophosphocholine; L-α-Glycerylphosphorylcholine; O-(sn-glycero-3-Phosphoryl)choline; Sn-Glycerophosphocholine; sn-Glycero-3-phosphorylcholine; α-Glycerophosphorylcholine; α-Glycerylphosphorylcholine. Grades: ≥95%. CAS No. 28319-77-9. Molecular formula: C8H20NO6P. Mole weight: 257.22.
sn-Glycerol-3-phosphate-[Glycerol-13C3] disodium salt
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α1E calcium channel (Cav2.3 from the CACNA1E gene). Alternative Names: SNX-482; SNX482; H-Gly-Val-Asp-Lys-Ala-Gly-Cys(1)-Arg-Tyr-Met-Phe-Gly-Gly-Cys(2)-Ser-Val-Asn-Asp-Asp-Cys(3)-Cys(1)-Pro-Arg-Leu-Gly-Cys(2)-His-Ser-Leu-Phe-Ser-Tyr-Cys(3)-Ala-Trp-Asp-Leu-Thr-Phe-Ser-Asp-OH; glycyl-L-valyl-L-alpha-aspartyl-L-lysyl-L-alanyl-glycyl-L-cysteinyl-L-arginyl-L-tyrosyl-L-methionyl-L-phenylalanyl-glycyl-glycyl-L-cysteinyl-L-seryl-L-valyl-L-asparagyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-prolyl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-histidyl-L-seryl-L-leucyl-L-phenylalanyl-L-seryl-L-tyrosyl-L-cysteinyl-L-alanyl-L-tryptophyl-L-alpha-aspartyl-L-leucyl-L-threonyl-L-phenylalanyl-L-seryl-L-aspartic acid (7->21),(14->26),(20->33)-tris(disulfide). Grades: >98%. CAS No. 203460-30-4. Molecular formula: C192H274N52O60S7. Mole weight: 4495.01.
S-(+)-O-Desmethyl-Venlafaxine-[d6]
(S)-(+)-O-Desmethyl Venlafaxine-[d6] is the deuterium labelled (S)-(+)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Alternative Names: HY-B0602S1; CS-0131892. Grades: 95%. CAS No. 1062609-99-7. Molecular formula: C16H19D6NO2. Mole weight: 269.37.
Sodium Cholate is used as a non-denaturing detergent for membrane protein extraction. Alternative Names: Cholic Acid Sodium Salt. Grades: >97.0%(GC)(T). CAS No. 361-09-1. Molecular formula: C24H39NaO5. Mole weight: 430.561.
Sodium Fluoroacetate-13C2
An isotope labelled of Sodium Fluoroacetate. Grades: 95% by HPLC; 98% atom 13C. Molecular formula: [13C]2H2FNaO2. Mole weight: 102.01.
Sodium pyruvate is the end product of glycolysis and is used for further metabolic cycles to provide energy for cells. Alternative Names: Propanoic acid, 2-oxo-, sodium salt (1:1); Pyruvic Acid Sodium Salt; Pyruvate Sodium; Propanoic acid, 2-oxo-, monosodium salt; Sodium 2-oxopropanoate; Sodium α-ketopropionate. Grades: ≥95%. CAS No. 113-24-6. Molecular formula: C3H3NaO3. Mole weight: 110.04.
Labelled Sodium pyruvate. Sodium pyruvate is the end product of glycolysis and is used for further metabolic cycles to provide energy for cells. Alternative Names: 2-Oxopropanoic Acid-2-13C, Sodium Salt; Pyruvic Acid-2-13C Sodium Salt; Sodium α-Ketopropionate-2-13C. Grades: 95%; 99% atom 13C. CAS No. 87976-70-3. Molecular formula: C2[13C]H3NaO3. Mole weight: 111.04.
Sodium Starch Glycolate
Sodium Starch Glycolate can be used in the synthesis of capsules for delivery of drugs or medicaments. Sodium Starch Glycolate is widely used in oral pharmaceuticals as a disintegrant in capsule and tablet formulations. Alternative Names: Sodium carboxymethyl starch; Carboxymethyl Starch Sodium Salt; Covagel; Crayon B 300P; Deprogel; Emsize CMS 100; Emsize CMS 60; Explosol; Explotab; Polvitex Z; Polytex 60; Primojel; Sodium CM-starch; Vivastar P; USP Sodium Starch Glycolate Type Al; starch carboxymethylether, sodium salt. CAS No. 9063-38-1. Molecular formula: (C2H4NaO3)x.
Solamargine
Solamargine, a steroidal alkaloid glycoside, is isolated from the fruits of a traditional Chinese medicinal herb called Solanum incanum L., triggered gene expression of human tumor necrosis factor receptor (TNFR) I which might lead to cell apoptosis. Uses: Anti-trypanosomal. Alternative Names: Solasodine-L-rhamnosido-D-glucoside; β-D-Glucopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-; (3β,22α,25R)-Spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside; NSC 407810; Solamargin; α-Solamargine; δ-Solanigrine. Grades: >98%. CAS No. 20311-51-7. Molecular formula: C45H73NO15. Mole weight: 868.06.
Solanesol
Solanesol, a high molecular weight isoprenoid alcohol isolated from tobacco leaf, could protect ethanol-induced L02 cell damage, which might be attributed to the activation of HO-1 and Hsp70. Solanesol could effectively scavenge lipid radicals to block lipid peroxidation, and inhibit effects on tyrosinase. Solanesol is a natural compound used in cosmetics material. Uses: Antioxidant / antibacterial. Alternative Names: 2,6,10,14,18,22,26,30,34-Hexatriacontanonaen-1-ol, 3,7,11,15,19,23,27,31,35-nonamethyl-, (2E,6E,10E,14E,18E,22E,26E,30E)-; (2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-Nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonaen-1-ol; 2,6,10,14,18,22,26,30,34-Hexatriacontanonaen-1-ol, 3,7,11,15,19,23,27,31,35-nonamethyl-, (all-E)-; Farnesylfarnesylfarnesol; Nonaisoprenol. Grades: 90%. CAS No. 13190-97-1. Molecular formula: C45H74O. Mole weight: 631.07.
Solid Chemical phosphorylation reagent II
Solid Chemical phosphorylation reagent II is a click chemistry reagent for the synthesis of oligonucleotides possessing 5'-terminal phosphate residues. Alternative Names: Chemical phosphorylation amidite; [3-(4,4'-Dimethoxytrityloxy)-2,2-dicarboxymethylamido]propyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-(methylamino)-2-[(methylamino)carbonyl]-3-oxopropyl 2-cyanoethyl ester; Solid Chemical Phosphorylation Reagent 2; 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(methylamino)-2-(methylcarbamoyl)-3-oxopropyl(2-cyanoethyl)(N,N-diisopropyl)phosphoramidite. Grades: ≥95%. CAS No. 202284-84-2. Molecular formula: C37H49N4O7P. Mole weight: 692.79.
Somatostatin-28 (1-14)
Somatostatin-28 (1-14) has been used to produce antibodies selective for somatostatin-28 that do not bind to the C-terminal fragment somatostatin-14. Alternative Names: H-SER-ALA-ASN-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-OH. CAS No. 79243-10-0. Molecular formula: C61H105N23O21S. Mole weight: 1528.71.
Sophoraflavanone H
Sophoraflavanone H is a natural compound isolated from the roots of Sophora moorcroftiana. Alternative Names: 2-[(2R,3R)-3-(3,5-dihydroxyphenyl)-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-5-yl]-5,7-dihydroxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one. Grades: 96.5%. CAS No. 136997-68-7. Molecular formula: C34H30O9. Mole weight: 582.6.
Sophoridine
Sophoridine comes from the roots of Sophora flavescens Ait. By regulating cytokine expression, Sophoridine possesses antiviral activities against Coxsackievirus B3, which may represent a potential therapeutic agent for viral myocarditis. Uses: Anti-arrhythmic; anti-tumor; anti-cancer; against coxsackievirus b3. Alternative Names: (5-beta)-matridin-15-on;l-sophoridine;5-EPIDIHYDROSOPHOCARPINE;DIHYDRO-5-EPISOPHOCARPINE. Grades: 0.96. CAS No. 6882-68-4. Molecular formula: C15H24N2O. Mole weight: 248.4.
Sorafenib
Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. Alternative Names: BAY 43-9006. Grades: >98%. CAS No. 284461-73-0. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.82.
Sorafenib tosylate
Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. Alternative Names: Sorafenib p-toluenesulfonate; BAY 43-9006 Mono-p-tosylate; BAY 54-9085; Nexavar(R); 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate); 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate); Bay 43-9006. Grades: ≥ 95%. CAS No. 475207-59-1. Molecular formula: C28H24ClF3N4O6S. Mole weight: 637.03.
Sotolone-[13C2]
Sotolone-[13C2] is the labelled analogue of Sotolone. Sotolone is a strong, very sweet, burnt flavor compound found in alcoholic beverages, coffee products, fenugreek, herbs, and spices. Alternative Names: [13C2]-Sotolone; 4,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C2; [13C2]-3-Hydroxy-4-methyl-2(5H)-Furanone; J-009301; 3-Hydroxy-4-methyl-5-methyl-13C-2(5H)-furanone-5-13C; Sautalone-13C2; Sotolon-13C2; Sotolone-13C2. Grades: 95% (CP); 99% atom 13C. CAS No. 156420-66-5. Molecular formula: C4[13C]2H8O3. Mole weight: 130.11.
Soya Lecithin
Soya Lecithin has emulsifying and lubricating properties and can be used as a surfactant. It is an antioxidant with free radical scavenging properties. Soya Lecithin has strong surface activity and colloidal properties, and plays an important role in cell metabolism and cell membrane permeability regulation. Soya Lecithin has good moisture and permeability to human skin, with antioxidant, antistatic, emulsifying, dispersing, wetting, penetrating, moisturizing, conditioning, softening, moisturizing and hair-softening functions. Alternative Names: soy lecithin; lecithins soya; lecithins, soybean. CAS No. 8030-76-0.
Spadin
Spadin is a potent and brain penetrating TREK-1 channel blocker (IC50 = 71 nM) displaying antidepressant activity. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis in adult mice. Alternative Names: Spadin; 1270083-24-3; Spadin (trifluoroacetate salt); HB5438; AKOS025293510; C96H142N26O22; S-1270083-24-3. CAS No. 1270083-24-3. Molecular formula: C96H142N26O22. Mole weight: 2012.34.
Spaglumic Acid
Spaglumic Acid is a peptide neurotransmitter and the third-most-prevalent neurotransmitter in the mammalian nervous system. NAAG consists of N-acetylaspartic acid and glutamic acid coupled via a peptide bond. Spaglumic Acid alsp acts as an NMDA receptor activator and mGlu3 receptor agonist. Alternative Names: N-Acetyl-L-aspartyl-L-glutamic acid; Isospaglumic acid; NAAG; N-Acetyl-Asp-Glu; N-acetylaspartylglutamate. Grades: ≥96% by HPLC. CAS No. 3106-85-2. Molecular formula: C11H16N2O8. Mole weight: 304.26.
(+)-Sparteine
Sparteine is a natural alkaloid extracted from scotch broom. It inhibits mAChR M2 and M4, and displays anticonvulsant effects. It also inhibits nAChR in the neurons. Uses: Anti-arrhythmia agents. Alternative Names: 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7R,7aR,14R,14aS)-; (7R,7aR,14R,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine; 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, [7R-(7α,7aα,14α,14aβ)]-; Pachycarpine; 6α,7β,9β,11β-Sparteine; D-(+)-Sparteine; D-Sparteine; d-Sparteine. Grades: ≥98%. CAS No. 492-08-0. Molecular formula: C15H26N2. Mole weight: 234.38.
Spathulenol
Spathulenol is isolated from the herbs of Salvia sclarea. It shows the capacity to inhibit proliferation in the lymphocytes, inducing apoptosis in these cells possibly through a caspase-3 independent pathway. Uses: Immunoinhibitory effect. Alternative Names: (1aR,4aR,7S,7aR,7bR)-1,1,7-Trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-ol; 10(14)-aromadendren-4-ol. Grades: 95%. CAS No. 6750-60-3. Molecular formula: C15H24O. Mole weight: 220.35.
SPDP
SPDP. Uses: A heterobifunctional cross-linker. Alternative Names: N-Succinimidyl 3-(2-Pyridyldithio)Propionate; UNII-2OHG8V08NL; SPDP NHS Ester; 3-(2-Pyridyldithio)Propionic Acid N-Hydroxysuccinimide Ester. Grades: ≥ 97% (HPLC). CAS No. 68181-17-9. Molecular formula: C12H12N2O4S2. Mole weight: 312.37.
Spectinomycin dihydrochloride pentahydrate
The dihydrochloride pentahydrate salt form of Spectinomycin, an aminoglycoside antibiotic isolated from Streptomyces spectabilis, has been found to be effective against gram-negative bacteria. Uses: Anti-bacterial agents. Alternative Names: Spectam; Spectogard; Spectinomycin HCl pentahydrate; Togamycin dihydrochloride pentahydrate; [2R-(2α,4aβ,5aβ,6β,7β,8β,9α,9aα,10aβ)]-Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4H-pyrano[2,3-b][1,4]benzodioxin-4-one Dihydrochloride Pentahydrate; Actinospectacin dihydrochloride pentahydrate. Grades: 98%. CAS No. 22189-32-8. Molecular formula: C14H24N2O7.2HCl.5H2O. Mole weight: 495.35.
Spectinomycin Sulfate
Spectinomycin sulfate is an aminocyclitol aminoglycoside antibiotic produced by Streptomyces spectabilis with bacteriostatic activity. It is active against gram-negative bacteria and used for the treatment of gonorrhea. Uses: Anti-bacterial agents. Alternative Names: Spectinomycin sulphate; NSC100859; (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one sulfate (1:1); Actinospectacin sulfate; 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, [2R-(2α,4aβ,5aβ,6β,7β,8β,9α,9aα,10aβ)]-, sulfate (1:1) (salt). Grades: 95%. CAS No. 23312-56-3. Molecular formula: C14H24N2O7.H2O4S. Mole weight: 430.43.
Spectinomycin Sulfate Tetrahydrate
An aminocyclitol antibiotic similar to aminoglycosides. Alternative Names: Actinospectacin tetrahydrate sulfate; 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, sulfate, hydrate (1:1:4). Grades: >95%. CAS No. 64058-48-6. Molecular formula: C14H24N2O7.H2O4S.4H2O. Mole weight: 502.49.
Spermidine-(butyl-[d8]) trihydrochloride
Spermidine-(butyl-[d8]) trihydrochloride is an isotopic compound of Spermidine trihydrochloride. Spermidine trihydrochloride is a polyamine that binds to NMDA receptor. Spermidine has been described as an agonist for its ability to enhance the binding of [3H]-MK801. It also acts as a NOS1 inhibitor. Alternative Names: Deuterated spermidine trihydrochloride; N-(3-Aminopropyl)-1,4-butane-d8-diamine trihydrochloride. Grades: 95% by CP; 98% atom D. CAS No. 1173019-26-5. Molecular formula: C7H14D8Cl3N3. Mole weight: 262.68.
Spermine-butane-[d8] tetrahydrochloride
Labelled spermine tetrahydrochloride. Spermine tetrahydrochloride is a polyamine that binds to and modulates NMDA receptor channel. Spermine also acts as a GluR inhibitor, PLCα inhibitor and PLCδ activator. Alternative Names: N,N'-Bis(3-aminopropyl)-1,4-butanediamine-d8(butane-d8) tetrahydrochloride; Spermine-[2H8] 4HCl. Grades: 95% by CP; 97% atom D. CAS No. 1173022-85-9. Molecular formula: C10H22D8Cl4N4. Mole weight: 356.23.
Spermine-[d20]
Isotopic labelled Spermine is an endogenous polyamine derived from spermidine. Spermine acts as an inhibitor of nNOS, and an antagonist of NMDA glutamate receptor. Alternative Names: N,N'-Bis(3-aminopropyl)-1,4-butanediamine-d20; N,N'-Bis(2-aminopropyl)tetramethylenediamine-d20; Gerontine-d20; Musculamine-d20; NSC 268508-d20; Neuridine-d20. Grades: >98%. Molecular formula: C10H6D20N4. Mole weight: 222.46.
sphingosine-[d7]
sphingosine-[d7] is the labelled analogue of sphingosine. Sphingosine is an amino alcohol with an 18-carbon unsaturated alkyl chain, forming a primary component of other sphingolipids. Alternative Names: D-erythro-sphingosine-d7; sphingosine-d7. Grades: 99% by CP; 99% atom D. CAS No. 1246304-34-6. Molecular formula: C18H30D7NO2. Mole weight: 306.54.