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Tobramycin-[13C6]
Tobramycin-[13C6] is a labelled analogue of Tobramycin which is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. Stable isotope labeled Tobramycin is intended for use as an internal standard for the quantification of Tobramycin by LC or GC-mass spectrometry, an alternative to immunoassay based quantification. Grades: 98%; 99% atom 13C. Molecular formula: C12[13C]6H37N5O9. Mole weight: 473.47.
Toceranib-[d8]
Labelled compound of Toceranib. Toceranib is a potent ATP-competitive PDGFR and VEGFR inhibitor (Ki = 5 and 6 nM, respectively), which inhibits phosphorylation of c-Kit and suppresses the growth of mast cell lines expressing mutant Kit, inducing cell cycle arrest and apoptosis. Also inhibits FGFR1 (Ki = 0.5 μM). Effective in vivo. Alternative Names: 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl-d8)ethyl]-1H-pyrrole-3-carboxamide; 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-(Pyrrolidin-1-yl-d8)ethyl)amide. CAS No. 1795134-78-9. Molecular formula: C22H17D8FN4O2. Mole weight: 404.51.
Tofacitinib-[13C3,15N]
One of the isotopic labelled form of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Alternative Names: CP-690550-13C3-15N. Grades: >98%. Molecular formula: C13[13C]3H20N5[15N]O. Mole weight: 316.18.
Tofacitinib citrate
Tofacitinib (trade name Xeljanz, formerly tasocitinib, CP-690550) is a drug discovered and developed by Pfizer. It is currently approved for the treatment of rheumatoid arthritis (RA) in the United States and is being studied for treatment of psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. (source: http://en.wikipedia.org / wiki / Tofacitinib). Uses: Janus kinase inhibitors. Alternative Names: CP-690550; CP 690550; CP690550; Tofacitinib; tasocitinib. Grades: 98%. CAS No. 540737-29-9. Molecular formula: C22H28N6O8. Mole weight: 504.5.
TOMATIDINE
Tomatidine is an alkaloid isolated from Lycopersicon Esculentum Mill with antibiotic and anti-inflammatory activities. Alternative Names: Tomatidin. Grades: 98%. CAS No. 77-59-8. Molecular formula: C27H45NO2. Mole weight: 415.65.
Toosendanin
Toosendanin is a natural diterpenoid compound found in the barks of Melia toosendan Sieb. et Zucc. Toosendanin shows hepatotoxicity and is also an effective insecticide for Ae. Alternative Names: 24-Norchola-20,22-diene-4-carboxaldehyde,3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-,cyclic4,19-hemiacetal, [C(R),1α,3α,4β, 5α,7α,12α,13α,14β,15β,17α]-;Chuanliansu;28-Deacetylsendanin;12-AcetoxyaMoorastatin. Grades: >98%. CAS No. 58812-37-6. Molecular formula: C30H38O11. Mole weight: 574.62.
Topiramate
Topiramate is a kainate GluR5 receptor antagonist, originally used as an anticonvulsant. Alternative Names: 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate. Grades: >98%. CAS No. 97240-79-4. Molecular formula: C12H21NO8S. Mole weight: 339.37.
Tosufloxacin tosylate
Tosufloxacin is a fluoroquinolone antibiotic with activity against Gram-positive and Gram-negative aerobic bacteria, anaerobic bacteria and Chlamydia trachomatis. It acts as an inhibitor of bacterial DNA gyrase and topoisomerase IV. Alternative Names: Tosuxacin; Ozex; 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid tosylate. Grades: ≥95%. CAS No. 115964-29-9. Molecular formula: C26H23F3N4O6S. Mole weight: 576.543.
Tosyl-L-proline
Tosyl-L-proline. Alternative Names: Tos-L-Pro-OH; (2S)-1-[(4-Methylphenyl)sulfonyl]pyrrolidine-2-carboxylic acid. Grades: ≥ 99% (TLC). CAS No. 51077-01-1. Molecular formula: C12H15NO4S. Mole weight: 269.32.
Totarol
Totarol is a naturally produced diterpenoid isolated from the barks of Podocarpus totara. Recent studies show that (+)-totarol has unique antimicrobial and therapeutic properties. Uses: Anti-bacteria. Alternative Names: 14-Isopropylpodocarpa-8,11,13-trien-13-ol;2-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, (4bS-trans)-;Podocarpa-8,11,13-trien-13-ol, 14-isopropyl-. Grades: >98%. CAS No. 511-15-9. Molecular formula: C20H30O. Mole weight: 286.46.
Tramiprosate-[d6]
Tramiprosate-[d6] is an isotope labelled form of Tramiprosate. Tramiprosate, also named homotaurine, is an orally-administered, sulfated glycosaminoglycan mimic that targets amyloid β. Alternative Names: 3-Aminopropane-d6-sulfonic Acid; Homotaurine-d6. Grades: 98% atom D. CAS No. 1131576-06-1. Molecular formula: C3H3D6NO3S. Mole weight: 145.21.
Tranexamic acid
Used as lysine analogue to characterize binding sites in plasminogen. Uses: Antifibrinolytic agents. Alternative Names: Tranexamic Acid; Cyklokapron; 4-(Aminomethyl)Cyclohexanecarboxylic Acid; Tranexamsaeure; Amstat; Trans AMCHA. Grades: > 98 %. CAS No. 1197-18-8. Molecular formula: C8H15NO2. Mole weight: 157.21.
Tranexamic Acid-[13C2,15N]
Labelled Tranexamic Acid (T714505). Antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic. Alternative Names: trans-4-(Aminomethyl)cyclohexanecarboxylic Acid-13C2,15N; trans-p-(Aminomethyl). CAS No. 1292837-95-6. Molecular formula: C613C2H1515NO2. Mole weight: 160.19.
(±)-trans-1,2-Diaminocyclohexane
(±)-trans-1,2-Diaminocyclohexane (CAS# 1121-22-8) is a reagent used in the thyroid receptor agonists for treatment of androgenetic alopecia. Alternative Names: (1R,2R)-cyclohexane-1,2-diamine. Grades: 95 %. CAS No. 1121-22-8. Molecular formula: C6H14N2. Mole weight: 114.19.
(±)-trans-1-(t-Butoxycarbonyl)-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid. Alternative Names: Boc-(±)-trans-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(4-chlorophenyl)-OH. Grades: ≥ 98% (HPLC). CAS No. 851485-00-2. Molecular formula: C16H20ClNO4. Mole weight: 325.79.
trans-2,cis-6-Nonadienal-[d2]
Trans-2,cis-6-Nonadienal-[d2] is a labelled analogue of trans-2,cis-6-Nonadienal. Alternative Names: (2E,6Z)-2,6-Nonadienal-D2; (E,Z)-2,6-Nonadienal-D2; (2E,6Z)-Nona-2,6-dienal-D2; (2E,6Z)-Nonadienal-D2; 2-trans-6-cis-Nonadienal-D2. Grades: >98%. CAS No. 221681-24-9. Molecular formula: C9H12D2O. Mole weight: 140.22.
trans-2-Hexen-1-al
trans-2-Hexen-1-al (CAS# 6728-26-3) is an unsaturated aldehyde that has an apple odour. trans-2-Hexenal is produced by soybean plants, and is also a sex pheromone produced by the female polyphemus moth. Alternative Names: (E)-hex-2-enal. Grades: 98.0 %. CAS No. 6728-26-3. Molecular formula: C6H10O. Mole weight: 98.14.
trans-3,5-Dimethoxy-4-hydroxycinnamaldehyde
Sinapaldehyde isolated from the heart wood of Populus tomentosa. It has effects against 65 strains of Candida. Uses: (e)-3-(4-hydroxy-3,5-dimethoxyphenyl)acrylaldehyde (cas# 4206-58-0) is a useful research chemical. Alternative Names: (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enal. Grades: 98 %. CAS No. 4206-58-0. Molecular formula: C11H12O4. Mole weight: 208.21.
trans-4-Fluoro-L-proline
trans-4-Fluoro-L-proline, a derivative of proline, functions as a pivotal component in the intricate process of drug development within the realms of pharmacology and chemical research. Employed predominantly for the innovation and formulation of therapeutic agents targeting an extensive array of pathological conditions such as oncological malignancies and neurodegenerative dysfunctions. Alternative Names: trans-4-Fluoro-L-Pro-OH; L-Proline, 4-fluoro-, (4R)-; (4R)-4-Fluoro-L-proline; L-Proline, 4-fluoro-, trans-; Proline, 4-fluoro-, L-trans-; (2S,4R)-4-Fluoro-pyrrolidine-2-carboxylic acid; trans-4-Fluoropyrrolidine-2-carboxylic Acid; L-trans-4-Fluoroproline; trans-4-Fluoroproline. Grades: ≥95%. CAS No. 2507-61-1. Molecular formula: C5H8FNO2. Mole weight: 133.12.
trans-4-Hydroxycinnamic acid
trans-4-Hydroxycinnamic acid isolated from the herb of Trifolium pratense. It has anti-bacteria effect against some gram-positive and gram-negative bacteria. Uses: Antibacterial; antimicrobial. Alternative Names: (e)-3-(4-hydroxyphenyl)-2-propenoicacid;(E)-p-Coumaric acid;(e)-p-coumaricacid;(E)-p-Hydroxycinnamic acid;(e)-p-hydroxycinnamicacid. Grades: 0.98. CAS No. 501-98-4. Molecular formula: C9H8O3. Mole weight: 164.2.
trans-4-Hydroxy-L-proline 7-amido-4-methylcoumarin is a fluorogenic substrate. Alternative Names: H-Hyp-AMC; (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid (4-methyl-2-oxochromen-7-yl)amide. Grades: 95%. CAS No. 77471-43-3. Molecular formula: C15H16N2O4. Mole weight: 288.31.
trans-Abacavir-[d4] Hydrochloride
trans-Abacavir-[d4] Hydrochloride is a deuterium labelled trans-Abacavir hydrochloride, which is an impurity of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Alternative Names: (1R,4R)-rel-4-[2-Amino-6-[cyclopropyl-d4)amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol Hydrochloride. CAS No. 1346605-40-0. Molecular formula: C14H15D4ClN6O. Mole weight: 326.82.
trans-Abacavir Dihydrochloride
trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Alternative Names: (1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Diydrochloride. Grades: 98%. Molecular formula: C14H20Cl2N6O. Mole weight: 359.25.
trans-Abacavir Hydrochloride
(1R,4R)-rel-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Diydrochloride. Alternative Names: The trans-isomer of Abacavir , a nucleoside reverse transcriptase inhibitor (NRTI). Abacavir USP impurity. Grades: > 95%. CAS No. 267668-71-3. Molecular formula: C14H18N6O.HCl. Mole weight: 359.25.
(-)-trans-anti-N2-BPDE-dG
(-)-trans-anti-N2-BPDE-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Alternative Names: [7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine; Benzo[a]pyrene, guanosine deriv.; (-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene. CAS No. 85026-87-5. Molecular formula: C30H27N5O7. Mole weight: 569.56.
trans-Cinnamic acid
Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and stimulating insulin secretion in vitro. Uses: Anaesthetic, anthelmintic. Alternative Names: 2-Propenoic acid, 3-phenyl-, (2E)-; (2E)-3-Phenyl-2-propenoic acid; 2-Propenoic acid, 3-phenyl-, (E)-; Cinnamic acid, (E)-; (2E)-2-Phenyl-2-propenoic acid; (2E)-3-Phenylprop-2-enoic acid; (2E)-Cinnamic acid; (E)-3-Phenyl-2-propenoic acid; (E)-3-Phenylacrylic acid; (2E)-3-Phenylacrylic acid; (E)-Cinnamic acid; 3-Phenyl-(E)-2-propenoic acid; NSC 44010; trans-3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid; trans-β-Carboxystyrene. Grades: ≥95%. CAS No. 140-10-3. Molecular formula: C9H8O2. Mole weight: 148.16.
trans-Cinnamyl acetate
trans-Cinnamyl acetate is isolated from the barks of Cinnamomum cassia Presl. It is a fragrance ingredient. Alternative Names: 2-Propen-1-ol, 3-phenyl-, 1-acetate, (2E)-; 2-Propen-1-ol, 3-phenyl-, acetate, (2E)-; 2-Propen-1-ol, 3-phenyl-, acetate, (E)-; Cinnamyl alcohol, acetate, (E)-; (2E)-3-Phenyl-2-propen-1-ol acetate; (E)-3-Acetoxy-1-phenyl-1-propene; (E)-3-Phenyl-2-propenyl acetate; (E)-3-Phenylallyl acetate; (E)-3-Phenylprop-2-en-1-yl acetate; (E)-Cinnamyl acetate; Acetic acid (E)-3-phenyl-2-propenyl ester; trans-3-Acetoxy-1-phenyl-1-propene; trans-3-Phenyl-2-propenyl acetate. Grades: ≥95%. CAS No. 21040-45-9. Molecular formula: C11H12O2. Mole weight: 176.21.
trans-Cyclooct-2-en-L-Lysine
trans-Cyclooct-2-en-L-Lysine. CAS No. 1801936-26-4. Molecular formula: C15H26N2O4. Mole weight: 298.38.
Transdermal Peptide
TD-1 binds to Na+/K+-ATPase beta-subunit (ATP1B1) and interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. Alternative Names: Transdermal Peptide 1. Grades: 98%. CAS No. 918629-48-8. Molecular formula: C40H66N14O16S2. Mole weight: 1063.17.
trans-Ferulic acid
Trans-ferulic (FA) acid is a natural phenylpropanoid found in herbs of Euphorbia hylonoma, it exhibits antioxidant effects in vitro. Trans-ferulic has inhibitory effect on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Uses: Antioxidant. Alternative Names: (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid. Grades: > 98 %. CAS No. 537-98-4. Molecular formula: C10H10O4. Mole weight: 194.18.
trans-Nerolidol
trans-Nerolidol is a farnesane sesquiterpenoid present in various flowers and plants with a floral odor. It is used as a flavoring agent, a cosmetic, a pheromone, a neuroprotective agent, an antifungal agent, an anti-inflammatory agent, an antihypertensive agent, an antioxidant, a volatile oil component, an insect attractant, and a herbicide. Alternative Names: 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (6E)-; (6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)-; (6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; (6E)-Nerolidol; (E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; (E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol; (±)-trans-Nerolidol; 1-Geranyl-2-methyl-3-buten-2-ol; Nerolidol B; (E)-Nerolidol. Grades: >95%. CAS No. 40716-66-3. Molecular formula: C15H26O. Mole weight: 222.37.
trans-Zeatin-[d5]
A labelled analogue of trans-Zeatin. Alternative Names: [2H5]trans-ZEATIN. Molecular formula: C10H8D5N5O. Mole weight: 224.27.
Trastuzumab deruxtecan
Trastuzumab deruxtecan is an antibody-drug conjugate consisting of humanized anti-HER2 antibody and a topoisomerase I inhibitor payload. Trastuzumab deruxtecan has been used in the research of HER2 expressing solid tumor therapy. Alternative Names: DS-8201a; T-DXd; DS-8201. CAS No. 1826843-81-5.
Trastuzumab emtansine
Trastuzumab emtansine is an antibody-drug conjugate (ADC) consisting of the recombinant anti-epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab conjugated to the maytansinoid DM1 via a nonreducible thioether linkage (MCC) with potential antineoplastic activity. The trastuzumab moiety of this ADC binds to HER2 on tumor cell surface surfaces. Upon internalization, the DM1 moiety is released and binds to tubulin, thereby disrupting microtubule assembly / disassembly dynamics and inhibiting cell division and the proliferation of cancer cells that overexpress HER2. Linkage of antibody and drug through a nonreducible linker has been reported to contribute to the improved efficacy and reduced toxicity of this ADC compared to similar ADCs constructed with reducible linkers. Grades: 95%. CAS No. 1018448-65-1. Molecular formula: C6448H9948N1720O2012S44·(C47H62ClN4O13S)n.
Trehalose
Trehalose is used for the lyoprotection of therapeutic proteins, especially for parenteral administration. It is also used as a color adjuvant, flavor enhancer, freeze-drying agent, humectant, stabilizer, sweetener, tablet diluent, and thickener. Alternative Names: D-Trehalose; D-(+)-Trehalose; α-D-Glucopyranosyl α-D-glucopyranoside; Cabaletta; Ergot Sugar; Mycose; NSC 2093; Natural Trehalose; O-D-Glucopyranosyl-(1→1)-D-glucopyranoside; Thealoz; Treha; Trehalose P; Trehaose; α,α-Trehalose; α,α'-D-Trehalose; α-D-Trehalose; α-Trehalose. Grades: 98%. CAS No. 99-20-7. Molecular formula: C12H22O11. Mole weight: 342.30.
Treprostinil-[d9]
Treprostinil-[d9] is a labelled form of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI2) that is used for the treatment of pulmonary arterial hypertension (PAH). Alternative Names: 2-{[(1R,2R,3aS)2-hydroxy-1-(3R)-3-hydroxy(4,4,5,5,6,6,7,7,7-D9)heptyl]-1H,2H,3H,3aH,4H,9H,9aH-yl]oxy}acetc acid. Grades: 95% by HPLC; 98% atom D. Molecular formula: C23H25O5D9. Mole weight: 399.58.
Triandrin
Triandrin is an extraordinary natural compound, demonstrating unprecedented antineoplastic prowess. Grades: 98.5%. CAS No. 19764-35-3. Molecular formula: C15H20O7. Mole weight: 312.32.
Trianthenol
Trianthenol is a natural compound found in several plants. Alternative Names: (4E)-5,9,13,17-Tetramethyl-2-(5,9,13-trimethyl-1-methylenetetradecyl)-4-octadecen-1-ol. Grades: >95%. CAS No. 333361-85-6. Molecular formula: C40H78O. Mole weight: 575.05.
Triazole-[13C2,15N3]
Triazole-[13C2,15N3]. Alternative Names: 1H-1,2,4-Triazole-3,5-13C2-1,2,4-15N3; Triazole-13C2,15N3. CAS No. 1261170-82-4. Molecular formula: [13C]2H3[15N]3. Mole weight: 74.03.
trichloroethoxycarbonyl chloride
trichloroethoxycarbonyl chloride is used in organic synthesis for the introduction of the trichloroethyl chloroformate (Troc) protecting group for amines, thiols and alcohols. It readily cleaves vs other carbamates and can be used in an overall protecting group strategy. Alternative Names: Troc-CL; Carbonochloridic acid, 2,2,2-trichloroethyl ester; 2,2,2-trichloroethylchloroformate; Chloroformic acid 2,2,2-trichloroethyl ester; Formic acid, chloro-, 2,2,2-trichloroethyl ester; Trichloroethyl chloroformate; 2,2,2-trichloroethoxycarbonyl chloride; 2,2,2-Trichloroethyl; 2,2,2 TRI CHLOROETHYL CHLOROFORMAT; 2,2,2-trichloroethyloxycarbonyl chloride. Grades: 98 % (GC). CAS No. 17341-93-4. Molecular formula: C3H2Cl4O2. Mole weight: 211.86.
Trichostatin A, also known as TSA, is an HDAC inhibitor. TSA inhibits the eukaryotic cell cycle during the beginning of the growth stage. TSA can be used to alter gene expression by interfering with the removal of acetyl groups from histones (histone deacetylases, HDAC) and therefore altering the ability of DNA transcription factors to access the DNA molecules inside chromatin. It is a member of a larger class of histone deacetylase inhibitors (HDIs or HDACIs) that have a broad spectrum of epigenetic activities. Uses: Reprogramming. Alternative Names: TSA; Antibiotic A-300; 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide. Grades: 98%. CAS No. 58880-19-6. Molecular formula: C17H22N2O3. Mole weight: 302.37.
Tricin 7-O-glucoside
Tricin 7-O-glucoside is a natural compound which can be isolated from Carex fraseriana, Poa secunda, etc. Alternative Names: Tricin 7-glucoside; tricin 7-O-beta-D-glucoside. Grades: 92%. CAS No. 32769-01-0. Molecular formula: C23H24O12. Mole weight: 492.43.
Triclocarban-[d4]
An isotope labelled form of Triclocarban. Triclocarban is an antibacterial agent common in personal care products. Alternative Names: 3,4,4'-Trichlorocarbanilide-d4; 3,4,4'-Trichlorodiphenylurea-d4; 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea-d4. Grades: 95% by HPLC; 98% atom D. CAS No. 1219799-29-7. Molecular formula: C13H5D4Cl3N2O. Mole weight: 319.61.
Triclosan-[d3]
Triclosan-[d3] is a labelled compound of Triclosan. Triclosan (Irgasan) is an antimicrobial agent found in many soaps and detergents, binds to bacterial ENR enzyme. Alternative Names: Triclosan D3; 5-Chloro-2-(2,4-dichloro-3,5,6-d3-phenoxy)phenol-d3; 2,4,4'-Trichloro-2'-hydroxydiphenyl-d3 Ether. Grades: 95% by HPLC; 98% atom D. CAS No. 1020719-98-5. Molecular formula: C12H4D3Cl3O2. Mole weight: 292.56.
Tricyclic amide linker resin (DL-form)
Ramage resin is highly suitable for the preparation of peptide amides by the Fmoc-strategy and is recommended for C-terminal Phe, Tyr and Ile. Alternative Names: Ramage amide linker resin (DL-form) (200-400 mesh).
Triethylamine-[d15]
Triethylamine-[d15]. Alternative Names: tris[(1,1,2,2,2-D15)ethyl]amine. Grades: 98% by CP; 98% atom D. CAS No. 66688-79-7. Molecular formula: C6D15N. Mole weight: 116.28.
Triethyl citrate
Triethyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. It is also used as a direct food additive for flavoring, for solvency, and as a surface active agent. Alternative Names: 2-Hydroxy-1,2,3-propanetricarboxylic acid triethyl ester; 2-Hydroxy-1,2,3-propanetricarboxylic Acid 1,2,3-Triethyl Ester; Citric Acid Triethyl Ester; Citroflex 2; Citroflex C 2; Citroflex EC; Citrofol AI; Ethyl citrate; Eudraflex; Hydragen CAT; NSC 8907. Grades: 98%. CAS No. 77-93-0. Molecular formula: C12H20O7. Mole weight: 276.28.
Triethyl-[silane-d]
Triethyl-[silane-d]. Alternative Names: Deuterated triethylsilane; Triethylsilane-d; Deuterotriethylsilane; Triethyl-silane-d. Grades: 99% by CP; 97% atom D. CAS No. 1631-33-0. Molecular formula: C6H15DSi. Mole weight: 117.28.
Trifluoroacetyl Tripeptide-2
Trifluoroacetyl Tripeptide-2 is a peptide derived from the activity of elastase inhibitory factor, it can reduce premature aging protein synthesis, improve skin flabby, sagging and wrinkles caused by it, at the same time, improve skin firmness and elasticity, improve facial contour. It has excellent emulsification, dispersion, antistatic, spreading, and wetting ability, avoiding the damage of residue to the natural protective layer of skin, and can be used for a long time. Alternative Names: TFA-VAL-TYR-VAL-OH; ECM-Protect; Progeline; L-Valine, N-(2,2,2-trifluoroacetyl)-L-valyl-L-tyrosyl-; N-(2,2,2-Trifluoroacetyl)-L-valyl-L-tyrosyl-L-valine; Peptide Progeline Trifluoroacetyl Tripeptide 2. CAS No. 64577-63-5. Molecular formula: C21H28F3N3O6. Mole weight: 475.47.
Trigonelline hydrochloride
Trigonelline has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and it has been shown to reduce diabetic auditory neuropathy and platelet aggregation. It acts by affecting β cell regeneration, insulin secretion, activities of enzymes related to glucose metabolism, reactive oxygen species, axonal extension, and neuron excitability. Uses: Hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor. Alternative Names: 1-METHYLPYRIDINIUM-3-CARBOXYLATE HYDROCHLORIDE; N-METHYLNICOTINIC ACID BETAINE HYDROCHLORIDE; TRIGONELLIN HYDROCHLORIDE; TRIGONELLINE HYDROCHLORIDE; TRIGONELLINE HCL; TIMTEC-BB SBB000182; 3-carboxy-1-methylpyridinium chloride; Trigonelline chloride. Grades: >98%. CAS No. 6138-41-6. Molecular formula: C7H8ClNO2. Mole weight: 173.6.
Triisopropylsilane
Protective agent of peptide synthesis. Alternative Names: Silane, triisopropyl-; Tris(1-methylethyl)silane; TIS; Triisopropylhydrosilane; Tris-isopropylsilane. Grades: ≥99% by GC. CAS No. 6485-79-6. Molecular formula: C9H22Si. Mole weight: 158.36.
Trimethoprim
Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections. It caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. It binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). Uses: Anti-infective agents, urinary; antimalarials; antimetabolites; folic acid antagonists. Alternative Names: Trimpex; Proloprim. Grades: >98%. CAS No. 738-70-5. Molecular formula: C14H18N4O3. Mole weight: 290.32.
Trimethoprim-[13C3]
Labelled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections. It caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. It binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). Alternative Names: 5-[(3,4,5-(Trimethoxy-13C3)yphenyl)methyl]-2,4-pyrimidinediamine; 2,4-Diamino-5-[3',4',5'-(trimethoxy-13C3)benzyl]pyrimidine; Instalac-13C3; Monotrim-13C3; Proloprim-13C3; Syraprim-13C3; Tiempe-13C3; Trimanyl-13C3; Uretrim-13C3. CAS No. 1189970-95-3. Molecular formula: C11[13C]3H18N4O3. Mole weight: 293.30.
Trimethoprim lactate
Trimethoprim lactate salt is used as an antibacterial agent, primarily active against most gram-negative and gram-positive aerobic bacteria. It inhibits dihydrofolate reductase. Alternative Names: Trimethoprim lactic Acid. Grades: ≥98%. CAS No. 23256-42-0. Molecular formula: C17H24N4O6. Mole weight: 380.39.
Trimethylamine-[d9] hydrochloride
Trimethylamine-[d9] hydrochloride. Alternative Names: N,N-Dimethylmethanamine-d9 Hydrochloride. Grades: 99% atom D. CAS No. 18856-86-5. Molecular formula: C3HD9ClN. Mole weight: 104.63.
Trimethylbromosilane
Powerful silylating agent. Alternative Names: Bromotrimethylsilane; Trimethylsilyl bromide. Grades: >95% by GC. CAS No. 2857-97-8. Molecular formula: C3H9BrSi. Mole weight: 153.09.
Trimethyl-[d9]-chlorosilane
Trimethyl-[d9]-chlorosilane. Alternative Names: Chlorotrimethyl-d9-silane; Chlorotri(methyl-d3)silane. Grades: 99% by CP; 99% atom D. CAS No. 20395-57-7. Molecular formula: C3D9ClSi. Mole weight: 117.70.
Trimethylphenylammonium Iodide-[d9]
Trimethylphenylammonium Iodide-[d9]. Alternative Names: Trimethylphenylammonium-d9 Iodide; N,N,N-Tris[(2H3)methyl]anilinium iodide. Grades: 95% atom D. CAS No. 88278-22-2. Molecular formula: C9H5D9IN. Mole weight: 272.17.
Tri-n-butyl-[d27]-amine
Tri-n-butyl-d27-amine (CAS# 1219805-78-3) is a useful isotopically labeled research compound. CAS No. 1219805-78-3. Molecular formula: C12D27N. Mole weight: 212.52.
Tripalmitin-[1,1,1-13C3]
Tripalmitin-[1,1,1-13C3] is the labelled analogue of Tripalmitin. Tripalmitin also known as tripalmitoylglycerol or glyceryl tripalmitate, belongs to the class of organic compounds known as triacylglycerols. It is a common fatty acid found in plants and animals. Tripalmitin is used in the preparation of solid lipid particles for oral delivery of drugs. Alternative Names: Glyceryl tri(palmitate-1-13C); 1,2,3-propanetriol tris(hexadecanoate-1-13C); Glyceryl tri(hexadecanoate-1-13C); Tripalmitin-carboxyls-13C3. Grades: 98% by CP; 99% atom 13C. CAS No. 168294-57-3. Molecular formula: C48[13C]3H98O6. Mole weight: 810.30.
Tripeptide-32
Tripeptide-32, also known as Chronolux, is a synthetic tripeptide composed of three amino acids: proline, serine, and threonine. This peptide is recognized for its hydrating benefits, as it helps to maintain skin moisture by preventing water loss. More remarkably, Tripeptide-32 is claimed to activate genes that regulate the skin's circadian rhythm, including CLOCK and PER1. By modulating the skin's biological clock, it enhances cellular vitality, extends cell lifespan, and protects against environmental stressors such as UV radiation, promoting the repair of DNA damage. This ingredient is particularly beneficial for individuals with irregular sleep patterns, such as night owls or those experiencing jet lag, as it helps to maintain the skin's repair processes during the night. Tripeptide-32 is widely used in cosmetic formulations for its anti-aging and skin repair properties, and it is generally considered safe for use. Alternative Names: Chronolux Tripeptide 32; H-Ser-Thr-Pro-NH2; STP; H-STP-NH2; L-Seryl-L-threonyl-L-prolinamide; Chronolux; Tripeptide 32. Grades: ≥95%. CAS No. 1185583-20-3. Molecular formula: C12H22N4O5. Mole weight: 302.33.
Triphenylphosphine-[d15]
Triphenylphosphine-[d15]. Alternative Names: Phosphine, tri(phenyl-d5)- (8CI,9CI). Grades: 98% atom D. CAS No. 24762-44-5. Molecular formula: C18D15P. Mole weight: 277.38.
Triphenyltin-[d15] chloride
Triphenyltin-[d15] chloride is a pivotal compound within the biomedical realm and finds extensive utility owing to its distinctive isotopic labeling capabilities. Scientists employ this product to investigate and monitor the intricacies surrounding drug pharmacokinetics, distribution patterns, and toxicity profiles in relation to multiple pharmaceutical agents and ailments. Facilitating precise analysis through its stable isotope constituent, Triphenyltin-[d15] chloride spearheads groundbreaking progressions in biomedicine, fostering cutting-edge advancements. Alternative Names: Chlorotri(phenyl-d5)-stannane. Grades: ≥98% by CP; ≥98% atom D. CAS No. 358731-94-9. Molecular formula: C18D15ClSn. Mole weight: 400.57.
Triphosgene-[13C3]
Triphosgene-13C3 is an isotope labelled compound of Triphosgene(T810500); an efficient carbonylating agent for liquid and solid-phase aza-peptide synthesis. Alternative Names: Bis(trichloromethyl)carbonate-13C3. CAS No. 1173019-90-3. Molecular formula: 13C3Cl6O3. Mole weight: 299.73.
Triptolide
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It has immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is an NF-κB activation inhibitor. Uses: Adcs cytotoxin. Alternative Names: NSC 163062; PG490; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one; (-)-Triptolide; PG 490; Triptolide. Grades: >98%. CAS No. 38748-32-2. Molecular formula: C20H24O6. Mole weight: 360.40.
Tris-(2-aminoethyl)amine resin
Tris-(2-aminoethyl)amine resin. Alternative Names: Polyamine resin.
Trisulfide Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Alternative Names: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 Trisulfide bridge); Octreotide EP Impurity E; D-Phenylalanyl-S-sulfanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2→7)-trisulfide; D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Trisulfide Bridge between Cys2-Cys7); D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Trisulfide Bridge between Cys2-Cys7); Octreotide impurity E; DPhe-CF-DTrp-KTC-Thr-ol(Cys2&Cys7 Trisulfide bridge). Grades: ≥95%. CAS No. 1546983-27-0. Molecular formula: C49H66N10O10S3. Mole weight: 1051.31.
Tropine
Tropine is found in the roots of Atropa belladonna. Alternative Names: Pseudotropine; 3-Tropanol. Grades: > 95 %. CAS No. 120-29-6. Molecular formula: C8H15NO. Mole weight: 141.21.