BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tropodithietic acid | Tropodithietic acid (TDA) is a broad-spectrum antibiotic produced by the marine bacterium Roseobacter gallaeciensis. It is effective against a variety of Gram-negative α-proteobacteria, γ-proteobacteria, and flavobacteria as well as Gram-positive actinobacteria strains in a disc assay. Alternative Names: TDA. Grades: ≥98%. CAS No. 750590-18-2. Molecular formula: C8H4O3S2. Mole weight: 212.25. |  |
| Tropolone | A bactericidal antibiotic composed of a seven membered aromatic ring. Alternative Names: Purpurocatechol. Grades: ≥ 99 %. CAS No. 533-75-5. Molecular formula: C7H6O2. Mole weight: 122.12. | |
| Troxerutin | Troxerutin, a natural bioflavonoid isolated from Sophora japonica., has been reported to have many benefits and medicinal properties. It can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation. Uses: Anticoagulants. Alternative Names: Trihydroxyethylrutin; Vitamin P4; Rufen-P4; 3',4',7-Tris[O-(2-hydroxyethyl)]rutin; 2-[3,4-Bis(2-hydroxyethoxy)phenyl]-3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one; Flavone, 3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-, 3-[6-O-(6-deoxy-α-L-mannopyranosyl)-β-Dglucopyranoside]; 3,5-Dihydroxy-3',4',7-tris(2-hydroxyethoxy)flavone 3-rutinoside; 3',4',7-Tri-O-(β-hydroxyethyl)rutoside; 3',4',7-Tris(hydroxyethyl)rutin; Factor P-Zyma; Posorutin; Ruven; THR; TriHER; Trioxyethylrutin; Tris(hydroxyethyl)rutin; Tris(hydroxyethyl)rutoside; Tris-O-(2-hydroxyethyl)rutin; Tris-O-(β-hydroxyethyl)rutoside; Troxerutine; Troxevazin; Vastribil; Veinamitol; Veniten; Venoruton P; Vitamin P; Z 6000. Grades: >98%. CAS No. 7085-55-4. Molecular formula: C33H42O19. Mole weight: 742.68. | |
| Trypanothione | Trypanothione is utilized as a substrate by trypanothione reductase, a unique enzyme found in trypanosomes and leishmanias (Km = 51 μM). Alternative Names: Oxidized trypanothione; N(1),N(8)-Bis(gamma-glu-hemi-cys-gly)sperimidine; L-γ-Glutamyl-L-cysteinyl-N-[3-[[4-[[N-(N-L-γ-glutamyl-L-cysteinyl)glycyl]amino]butyl]amino]propyl]-glycinamide Cyclic (2→3)-disulfide; TS2. CAS No. 96304-42-6. Molecular formula: C27H47N9O10S2. Mole weight: 721.85. | |
| Tryptamine-[d4] HCl | Tryptamine-[d4] HCl is the labelled analogue of Tryptamine Hydrochloride. Tryptamine is an agonist of hTAAR1. Alternative Names: 1H-Indole-3-ethanamine-d4 Hydrochloride; 3-(2-Aminoethyl-d4)indole Hydrochloride; 2-(1H-Indol-3-yl)ethan-1-amine-d4 Hydrochloride; 2-(1H-Indol-3-yl)ethanamine-d4 Hydrochloride; 2-(1H-Indol-3-yl)ethylamine-d4 Hydrochloride; 2-(3-Indolyl) ethylamine-d4 Hydrochloride; 3-(2-Aminoethyl)-1H-indole-d4 Hydrochloride; 3-(2-Aminoethyl)indole-d4 Hydrochloride; 3-Indoleethanamine-d4 Hydrochloride; 3-Indoleethylamine Hydrochloride. Grades: 95% by HPLC; 98% atom D. CAS No. 340257-60-5. Molecular formula: C10H9D4ClN2. Mole weight: 200.70. | |
| Tryptophan | As a bifunctional catalyst for asymmetric selective synthesis, D-Tryptophan are widely used in pharmaceutical, agricultural chemicals, flavors, spices and materials industries. Alternative Names: D-Trp-OH; (R)-2-Amino-3-(3-indolyl)propionic acid. Grades: ≥ 99% (Assay). CAS No. 153-94-6. Molecular formula: C11H12N2O2. Mole weight: 204.20. | |
| TT-232 | TT 232 is a somatostatin analog that acts as a peptide agonist for sst1/sst4 somatostatin receptors. TT 232 inhibits tyrosine kinase activity in human colon tumor cell lines. TT 232 was shown to suppress proliferation and induce apoptosis in a pancreatic tumor cell line. Alternative Names: TT2-32; TT2 32; TT232; TT-232; TT 232; CAP 232; CAP-232; CAP232. CAS No. 147159-51-1. Molecular formula: C45H58N10O9S2. Mole weight: 947.13. | |
| (+)-TUBOCURARINE CHLORIDE PENTAHYDRATE | Tubocurarine is a toxic alkaloid. It is an acetylcholine receptor (AChR)-blocking agent. Tubocurarine is now rarely used as an adjunct for clinical anesthesia because safer alternatives like cisatracurium and rocuronium. Uses: Clinical anesthesia. Alternative Names: UNII-900961Z8VR; D-Tubocurarine chloride pentahydrate; (+)-Tubocurarine chloride pentahydrate; (+)-Tubocurarine chloride hydrochloride pentahydrate. Grades: 97%. CAS No. 6989-98-6. Molecular formula: C37H41ClN2O6·HCl·5H2O. Mole weight: 771.72. | |
| Tulathromycin A | Tulathromycin A is a triamilide antibiotic used for the treatment of bovine and porcine respiratory disease. It exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Uses: Anti-bacterial agents. Alternative Names: Tulathromycin; Draxxin; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one; CP 472295; Increxxa; Lydaxx; Traxovet; Tulathrin; Tulaven; Tulinovet; Tulissin. Grades: 98% by HPLC. CAS No. 217500-96-4. Molecular formula: C41H79N3O12. Mole weight: 806.08. | |
| Tusamitamab ravtansine | Tusamitamab ravtansine is an antibody-drug conjugate consisting of an anti-carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) antibody conjugated to the potent cytotoxic antitubulin DM4. It has been used in the research of solid tumor treatment. Alternative Names: SAR-408701; SAR 408701; SAR408701. CAS No. 2254086-60-5. | |
| Tylosin | Tylosin is a 16-member-ring macrolide produced through the fermentation of Streptomyces fradiae, a species of actinobacteria found in soil. It is effective against gram-positive bacteria, Mycoplasma species and certain gram-negative bacteria. With other macrolides, tylosin inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome and disrupting aminoacyl-and peptidyl-tRNA transcription. This is believed to ultimately prevent the bacteria from reproducing. Alternative Names: Tylosine; Tylocine; Tylosinum; Fradizine; NSC758961; (10E,12E)-(3R,4S,5S,6R,8R,14S,15R)-14-((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxymethyl)-5-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-dimethylamino-beta-D-glucopyranosyl)oxy)-6-formylmethyl-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide. Grades: >98%. CAS No. 1401-69-0. Molecular formula: C46H77NO17. Mole weight: 916.10. | |
| Tylosin B | It is a 16-membered macrolide antibiotic and a metabolite of Tylosin. It is also a precursor of Tilmicosin. Alternative Names: Desmycosin; 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)tylosin; Demycarosyltylosin. Grades: ≥95.0% by HPLC. CAS No. 11032-98-7. Molecular formula: C39H65NO14. Mole weight: 771.93. | |
| Tylosin monotartrate | Tylosin tartrate is a macrolide antibiotic produced by Streptomyces. Tylosin tartrate is an antimicrobial for gram-positive bacteria and mycoplasma. It can be used to prevent and treat respiratory diseases such as mycoplasma pneumonia, pleuropneumonia, swine pneumonia, Haemophilus parasuis, streptococcus suis, and other tissue infections. Alternative Names: Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt); Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt); Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin tartrate. Grades: >98%. CAS No. 74610-55-2. Molecular formula: C50H83NO23. Mole weight: 1066.19. | |
| Tylvalosin | Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Alternative Names: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. Grades: 90%. CAS No. 63409-12-1. Molecular formula: C53H87NO19. Mole weight: 1042.25. | |
| Tyr-Ala | Tyr-Ala. Alternative Names: Tyrosyl-Alanine; L-tyrosyl-L-alanine; L-Alanine, L-tyrosyl-; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)propanoic acid. CAS No. 730-08-5. Molecular formula: C12H16N2O4. Mole weight: 252.27. | |
| Tyramine-[d4] Hydrochloride | Tyramine-[d4] HCl is a labelled analogue of Tyramine HCl. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Alternative Names: 4-(2-Aminoethyl-d4)phenol Hydrochloride; 2-(4-Hydroxyphenyl)ethyl-1,1,2,2-d4-amine Hydrochloride; Mydrial-d4. Grades: 95% by HPLC; 98% atom D. CAS No. 1189884-47-6. Molecular formula: C8H8D4ClNO. Mole weight: 177.66. | |
| Tyramine hydrochloride | A naturally occurring derivative of tyrosine. A catecholamine releasing agent that promotes blood pressure elevation. Uses: Tyramine hydrochloride has been:coinfused with adenosine in control subjects and patients in order to reduce leg blood flow by 50% without affecting arterial blood pressurelabelled with fluorescence dyes (atto 488 and atto 655) to serve as a substrate for peroxidase in immunofluorescence analysisused in dimethylformamide, labelled with 5-(and-6)carboxyfluorescein, succinimidyl ester / biotin to serve as a substrate for peroxidase in tyramide signal amplification. Alternative Names: 4-(2-Aminoethyl)phenol hydrochloride; 4-Hydroxyphenethylamine hydrochloride. Grades: 98.0%. CAS No. 60-19-5. Molecular formula: C8H11NO·HCl. Mole weight: 173.64. | |
| Tyr-Asp | L-tyrosyl-L-aspartic acid is a dipeptide composed of tyrosine and aspartic acid. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-tyrosyl-L-aspartic acid; YD dipeptide; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)succinic acid. Grades: >90% by HPLC. CAS No. 87085-11-8. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
| Tyrocidine A | Tyrocidine A is a peptide antibiotic originally isolated from Bac. brevis. It is resistant to gram-positive bacteria and protozoa as well as to a lesser degree to gram-negative bacteria, and it is also resistant to yeast. Alternative Names: TrcA; cyclo-(D-PheProPhe-D-PheAsnGlnTyrValOrnLeu); cyclo(L-asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-phenylalanyl). CAS No. 1481-70-5. Molecular formula: C66H87N13O13. Mole weight: 1270.47. | |
| Tyrosyl-serine | Tyrosyl-serine is a dipeptide composed of tyrosine and serine. Alternative Names: L-Tyrosyl-L-serine. CAS No. 13588-99-3. Molecular formula: C12H16N2O5. Mole weight: 268.27. | |
| Tyrothricin | Tyrothricin is a mixture of antibiotics isolated from Bacillus brevis. Alternative Names: Bactralycin; Dermotricine; Hydrotricine; Coltirot; Martricin. Grades: >95%. CAS No. 1404-88-2. Molecular formula: C65H85N11O13. Mole weight: 1228.4. | |
| Tyr-Phe | Tyr-Phe. Alternative Names: Tyrosyl-Phenylalanine; L-tyrosyl-L-phenylalanine; L-Phenylalanine, L-tyrosyl-; L-Tyr-L-Phe-OH; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-3-phenylpropanoic acid. CAS No. 17355-11-2. Molecular formula: C18H20N2O4. Mole weight: 328.36. | |
| UCN-01 | KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activity. It inhibits many phosphokinases, including the serine / threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting apoptosis. Uses: Antineoplastic agents. Alternative Names: Antibiotic UCN 01; UCN01; Staurosporine; 7-hydroxystaurosporine; KW-2401; KW 2401; KW2401; (3R,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; (+)-UCN-01; KRX 0601; NSC 638850. Grades: >99% by HPLC. CAS No. 112953-11-4. Molecular formula: C28H26N4O4. Mole weight: 482.53. | |
| [UL-13C6gal]Lactose Monohydrate | [UL-13C6gal]Lactose Monohydrate is the labelled analogue of D-Lactose Monohydrate, which is used in the synthesis of casing for various methods of oral drug delivery, including dissolving pellets, and long-lasting pellets. Alternative Names: [1',2',3',4',5',6'-13C6]lactose monohydrate; 4-O-beta-D-[UL-13C6]galactopyranosyl-D-glucose; lactose-1',2',3',4',5',6'-13C6 monohydrate. Molecular formula: C6[13C]6H24O12. Mole weight: 366.27. | |
| Ularitide | Urodilatin is a hormone that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Alternative Names: Urodilatin; Urodilatin ularitide. Grades: ≥98% by HPLC. CAS No. 115966-23-9. Molecular formula: C145H234N52O44S3. Mole weight: 3505.93. | |
| Ungerine Nitrate | Alkaloid , from plants of the Ungernia genus, Amaryllidaceae. Grades: 97 % (TLC). Molecular formula: C18H20N2O8. Mole weight: 392.36. | |
| Uracil | Uracil is one of the four nucleobases in the nucleic acid of RNA, and can be used for drug delivery and as a pharmaceutical. Alternative Names: Cytarabine Impurity D; Pyrimidin-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxopyrimidine; 2,4-Pyrimidinedione; Pirod; Pyrod; Fluorouracil Impurity C; 1,2,3,4-Tetrahydropyrimidine-2,4-dione; 2,4-Dihydroxypyrimidine; 2,4-Pyrimidinediol; 4-Hydroxyuracil; Hybar X; NSC 3970; Lamivudine EP Impurity F; Fluorouracil EP Impurity C; Cytarabine EP Impurity D. Grades: >98%. CAS No. 66-22-8. Molecular formula: C4H4N2O2. Mole weight: 112.09. | |
| Urea-[13C] | Labelled Urea. Urea serves an important role in the metabolism of nitrogen-containing compounds by animals, and is the main nitrogen-containing substance in the urine of mammals. It is colorless, odorless solid, highly soluble in water, and practically non-toxic (LD50 is 15 g/kg for rats). Dissolved in water, it is neither acidic nor alkaline. The body uses it in many processes, most notably nitrogen excretion. Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Alternative Names: Carbamide-13C; Carbonyldiamide-13C. Grades: 99% by CP; 99% atom 13C. CAS No. 58069-82-2. Molecular formula: [13C]H4N2O. Mole weight: 61.05. | |
| Urea-[15N2] | Urea-[15N2]. Alternative Names: Urea-15N2; Aquacare-15N2; Aquadrate-15N2; B-I-K-15N2; Basodexan-15N2; Benural 70-15N2; Carbamide-15N2; Carbamimidic Acid-15N2; Carbonyl Diamide-15N2; Carmol 40-15N2; Keratinamin-15N2; Urepearl-15N2. Grades: 99% atom 15N. CAS No. 2067-80-3. Molecular formula: CH4[15N]2O. Mole weight: 62.04. | |
| Uridine | Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond. Alternative Names: Cytarabine Impurity B; 1-β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Ribofuranosyluracil; NSC 20256; Uracil riboside; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uridin; β-Uridine; Cytarabine EP Impurity B. Grades: ≥98% by HPLC. CAS No. 58-96-8. Molecular formula: C9H12N2O6. Mole weight: 244.20. | |
| Urocanic acid | It is produced by the strain of Bac. subtilis var. theronophilus. Urocanic acid has an inhibitory effect on Eichner's ascites pain in animals. Alternative Names: 4-imidazoleacrylic acid; trans-Urocanic acid; 5-Imidazoleacrylic acid; (2E)-3-(1H-IMIDAZOL-4-YL)ACRYLIC ACID; 3-(1H-Imidazol-4-yl)-2-propenoic acid; NSC 66357. Grades: 99%. CAS No. 104-98-3. Molecular formula: C6H6N2O2. Mole weight: 138.12. | |
| Uroguanylin | Uroguanylin belongs to the guanylin family of cyclic guanosine monophosphate (cGMP) regulatory peptides. Uroguanylin activates the guanylate cyclase-C / cyclic guanosine monophosphate pathway to induce analgesic effects in colonic hypersensitive animal models, revealing a new approach for the treatment of abdominal pain. Alternative Names: Uroguanylin Topoisomer A (human); UGN Topoisomer A (human); H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15); UGN (human); L-asparagyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-alpha-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparagyl-L-valyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-leucine (4->12),(7->15)-bis(disulfide); L-Asparaginyl-L-α-aspartyl-N-{(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-10-(2-amino-2-oxoethyl)-22-(2-carboxyethyl)-38-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl}-32-[(1R)-1-hydroxyethyl]-19-isobutyl-7,13-diisopropyl-4-methyl-3,6,9,12,15,18,21,24,30,33,36-undecaoxo-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37-undecaazabicyclo[14.13.13]dotetracont-25-yl}-L-α-asparagine. Grades: ≥90% by HPLC. CAS No. 154525-25-4. Molecular formula: C64H102N18O26S4. Mole weight: 1667.86. | |
| Urolignoside | Urolignoside is isolated from the herbs of Lysimachia clethroides. Urolignoside shows antioxidant and radical scavenging activities. Alternative Names: (7S,8R)-Urolignoside. Grades: 98.0%. CAS No. 131723-83-6. Molecular formula: C26H34O11. Mole weight: 522.54. | |
| Urolithin A | Urolithin A is a secondary metabolite of ellagitannins by the gut bacteria. It exhibits anti-inflammatory, antioxidant and antiproliferative effects. Urolithin A can cross the blood brain barrier thus has the potential therapeutic effect against Alzheimer's Disease. Alternative Names: 3,8-dihydroxy-6H-benzo[c]chromen-6-one; 3,8-Dihydroxy-6H-dibenzo(b,d)pyran-6-one; 6H-Dibenzo[b,d]pyran-6-one, 3,8-dihydroxy-. Grades: ≥98% by HPLC. CAS No. 1143-70-0. Molecular formula: C13H8O4. Mole weight: 228.20. | |
| Ursodeoxycholic-[24-13C] acid | Ursodeoxycholic-[24-13C] acid is an isotope analogue of Ursodeoxycholic acid (UDCS) which is a cell protectant used extensively to mitigate hepatic and biliary diseases. Alternative Names: (4R)-4-((3S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic-1-13C acid. Grades: 98%. CAS No. 63296-46-8. Molecular formula: C23[13C]H40O4. Mole weight: 393.56. | |
| Ursodeoxycholic Acid | Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases. Ursodeoxycholic acid may be used to study its specific activities that range from reduction of cholesterol absorpition, cholesterol gallstone dissolution to suppression of immune response.IC50: M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); NTCP: IC50=3.6 μM (human); HCT-116: IC50=>50 μM (human); GBM: IC50=>50 μM (human) Asbt: Ki=75 μM (human). Uses: Gallstone-dissolving drugs; anti-neoplastic; for the prevention and treatment of cholesterol gallstones; reduces hydrophobic bile acids and decreases both lymphocyte reactivity and serum alkaline phosphatase levels,ic50: m1-family aminopeptidase: ic50=2.6 μm (plasmodium falciparum 3d7); ntcp: ic50=3.6 μm (human); hct-116: ic50=>50 μm (human); gbm: ic50=>50 μm (human) asbt: ki= 75 μm (human). Alternative Names: 5beta-cholanic acid-3alpha,7beta-diol; Actigall; ursodeoxycholate; ursodiol; Ursodeoxycholic acid. Grades: ≥ 99.0%. CAS No. 128-13-2. Molecular formula: C24H40O4. Mole weight: 392.57. | |
| Ursolic acid | Ursolic acid is a natural pentacyclic triterpenoid carboxylic acid displaying antitumor activity. It was shown to downregulate the MMP-2 and uPA expression, and also inhibit Na+/K+-ATPase activity (IC50 = 24.7 μM) as well as NF-κB activation in various cancer cell lines. Ursolic acid can induce apoptosis in cancer cells. Ursolic acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics. Uses: Antidepressant. Alternative Names: NSC-167406; NSC-4060; NSC167406; NSC4060; NSC 167406; NSC 4060; Malol; Prunol; Urson; 3beta-Hydroxyurs-12-en-28-oic acid. Grades: ≥ 98%. CAS No. 77-52-1. Molecular formula: C30H48O3. Mole weight: 456.711. | |
| Ursonic acid | Ursonic acid isolated from the dried fruit of Ziziphus jujuba. It can be used in depression treatment medicine. Uses: Antihypertensive; antiasthmatic; antiviral activity. Alternative Names: 3-Oxours-12-en-28-oic acid. Grades: 97.5%. CAS No. 6246-46-4. Molecular formula: C30H46O3. Mole weight: 454.7. | |
| (-)-USNIC ACID | (-)-USNIC ACID. Alternative Names: (-)-USNEIN; (9bS)-2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl(2H,9bH)-dibenzofuran-1,3-dione; (-)-USNIC ACID 97%; (-)-USNEIN 97%; (9bS)-7,9-Dihydroxy-2,6-diacetyl-8,9b-dimethyldibenzofuran-1,3(2H,9bH)-dione; [9bS,(-)]-2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibe. CAS No. 6159-66-6. Molecular formula: C18H16O7. Mole weight: 344.32. | |
| Uvaol | Uvaol, also called urs-12-ene-3β,28-diol is a natural triterpenoid found in the herbs of Callicarpa bodinieri Levl. Urs-12-ene-3β,28-diol exhibits the activity of anti-inflammatory. Urs-12-ene-3β,28-diol also has has anti-proliferative activity,inhibits the angiotensin II-induced proliferation in a PPAR-γ-dependent manner, while at high doses they activate pathways of programmed cell death that are dependent on JNK and PPAR-γ. Uses: Anti-inflammatory; anti-proliferative. Alternative Names: Urs-12-ene-3β,28-diol. Grades: >98%. CAS No. 545-46-0. Molecular formula: C30H50O2. Mole weight: 442.7. | |
| Vaborbactam-[13C2,d3] | Labelled Vaborbactam. Vaborbactam is a selective beta-lactamase inhibitor under the development of Rempex Pharmaceuticals. Vaborbactam is a broad-spectrum inhibitor, especially restoring the activity of carbapenems against KPC-producing strains. Combined with a carbapenem, Vaborbactam can be a promising product for the treatment of multidrug resistant Gram-negative bacteria. Phase III clinical trials for the treatment of Bacteraemia, Gram-negative infections, Pneumonia, Pyelonephritis and Urinary tract infections are on-going. Alternative Names: 2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid-13C2,D3. Molecular formula: C10[13C]2H13D3BNO5S. Mole weight: 302.14. | |
| Val-Arg | Val-Arg. Alternative Names: L-valyl-L-arginine; valylarginine; VR dipeptide; L-Val-L-Arg; Valine Arginine dipeptide. CAS No. 37682-75-0. Molecular formula: C11H23N5O3. Mole weight: 273.33. | |
| Val-Cit-PAB-MMAE | Val-Cit-PAB-MMAE, a tubulin polymerase inhibitor, is a drug-linker conjugate for ADC. It contains an ADC linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE. Alternative Names: L-Valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide. Grades: ≥98%. CAS No. 644981-35-1. Molecular formula: C58H94N10O12. Mole weight: 1123.43. | |
| Valdecoxib | Valdecoxib is a selective COX-2 inhibitor. Uses: Cyclooxygenase 2 inhibitors. Alternative Names: SC-65872; SC65872; SC 65872; Valdecoxib; Bextra 4-(5-methyl-3-phenyl-4-isoxazolyl)-benzenesulfonamide. Grades: > 95%. CAS No. 181695-72-7. Molecular formula: C16H14N2O3S. Mole weight: 314.4. | |
| Valeraldehyde-[d9] (Pentanal-[d9]) | Valeraldehyde-D9 is the labeled compound of Valeraldehyde(V091295). Valeraldehyde is a volatile flavor compound found in many food products. It is also used as a reagent to prepare derivatives of Ferulic acid (F308900) and Caffeic acid (C080000) which exhibit anticancer properties. Alternative Names: Pentanal-D9; NSC 35404-D9; Pentylaldehyde-D9; Valeral-D9; Valeric Acid Aldehyde-D9; Valeric Aldehyde-D9; n-Pentanal-D9; n-Valeraldehyde-D9; Pentanal-2,2,3,3,4,4,5,5,5-d9. CAS No. 148587-08-0. Molecular formula: C5HD9O. Mole weight: 95.19. | |
| Valerenic acid | Valerenic acid is a positive allosteric modulator of GABAA receptors displaying selectivity for receptors containing β2 or β3 subunits. Valerenic acid exhibits sedative, anticonvulsant and anxiolytic effects in vivo. Valerenic acid also acts as a partial agonist of 5-HT5A receptors. Alternative Names: valerinic acid; (-)-valerenic acid. Grades: ≥99% by HPLC. CAS No. 3569-10-6. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Valeric acid-[3,4,5-13C3] | Valeric acid-[3,4,5-13C3]. Alternative Names: Pentanoic acid-3,4,5-13C3; Valeric acid-3,4,5-13C3. Grades: 98% (CP); 99% atom 13C. CAS No. 1173023-05-6. Molecular formula: C2[13C]3H10O2. Mole weight: 105.11. | |
| Valerosidate | Valerosidate is extracted from the herbs of Valeriana jatamansi. Alternative Names: [(1S)-1,4aα,5,6,7,7aα-Hexahydro-6α,7β-dihydroxy-7-methyl-1α-(3-methyl-1-oxobutoxy)cyclopenta[c]pyran-4-yl]methyl β-D-glucopyranoside; Valerosidatum; [(1S,4aS,6S,7S,7aS)-6,7-dihydroxy-7-methyl-4-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-1-yl] 3-methylbutanoate. Grades: 0.99. CAS No. 29505-31-5. Molecular formula: C21H34O11. Mole weight: 462.49. | |
| Valinomycin | A hydrophobic cyclodepsipeptide with potent antitumour activity; a highly selective potassium ionophore; a biosensor to detect potassium efflux. Alternative Names: Potassium ionophore I; valino; Valinomicin; NSC122023; Antibiotic N-329 B; cyclo[-D-O-Val-D-Val-L-O-Ala-L-Val]3; BRN 0078657; (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone. Grades: >95% by HPLC. CAS No. 2001-95-8. Molecular formula: C54H90N6O18. Mole weight: 1111.32. | |
| Valnemulin | Valnemulin is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. Alternative Names: Econor; Biotilina. Grades: >99% by HPLC. CAS No. 101312-92-9. Molecular formula: C31H52N2O5S. Mole weight: 564.82. | |
| Valnemulin hydrochloride | The hydrochloride salt form of Valnemulin is a wide-spectrum antibiotic that has been found to have strong antibacterial activity especially against mycoplasma and spirochete, and is commonly used as a veterinary drug. It can prevent and control swine dysentery, ileitis, colitis and other intestinal diseases, as well as swine asthma and other respiratory diseases. Alternative Names: Valnemulin HCl; UNII-W1GDP58BNQ; W1GDP58BNQ. Grades: >90%. CAS No. 133868-46-9. Molecular formula: C31H53ClN2O5S. Mole weight: 601.28. | |
| Valproic acid-[d6] | One of the isotopic labelled form of Valproic Acid, which could be used as an antiepileptic agent. Alternative Names: 2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid; Dipropylacetic Acid-d6; 2-Propylvaleric Acid-d6. Grades: 95% by HPLC; 98% atom D. CAS No. 87745-18-4. Molecular formula: C8H12D6O2. Mole weight: 150.25. | |
| Val-Pro-Pro | Val-Pro-Pro is an angiotensin-converting enzyme inhibitor. Uses: Angiotensin-converting enzyme inhibitors. Alternative Names: L-Valyl-L-prolyl-L-proline; L-Proline, 1-(1-L-valyl-L-prolyl)-. Grades: >98%. CAS No. 58872-39-2. Molecular formula: C15H25N3O4. Mole weight: 311.38. | |
| Valsartan | Valsartan is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure. Uses: Angiotensin ii type 1 receptor blockers; antihypertensive agents. Alternative Names: CGP48933, CGP-48933, CGP 48933, Valsartan, Diovan, Miten, Nisis, Prova, Tareg, Vals, Walsartan. Grades: >98%. CAS No. 137862-53-4. Molecular formula: C24H29N5O3. Mole weight: 435.52. | |
| Valsartan methyl ester | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Alternative Names: Valsartan Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Methyl Ester. Grades: 98.0%. CAS No. 137863-17-3. Molecular formula: C25H31N5O3. Mole weight: 449.56. | |
| Valtrate | Valtrate is a natural iridoid compound isolated from the roots of Valeriana officinalis L. Valtrate is a new class of cytotoxic and antitumor agent. Valtrate may also have a potential anxiolytic effect on the psychic symptoms of anxiety. Uses: Antitumor. Alternative Names: Valepotriate; [(1S,6S,7aS)-4-(Acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-methylbutanoate. Grades: >98%. CAS No. 18296-44-1. Molecular formula: C22H30O8. Mole weight: 422.47. | |
| Vancomycin | Tricyclic glycopeptide antibiotic. Inhibits cell wall synthesis in Gram-positive bacteria. Pharmacologically active in vivo. Alternative Names: Vancocin; Vancomycinum; Vancomicina; Vancomycine; (S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-((S)-6-hydroxy-2-imino-hexahydro-pyrimidin-4-yl)-9,12-bis-hydroxymethyl-2,5,8,11,14-pentaoxo-6-[1-ureido-meth-(Z)-ylidene]-1,4,7,10,13pentaaza-cyclohexadec-15-yl}-amide. Grades: >98%. CAS No. 1404-90-6. Molecular formula: C66H75Cl2N9O24. Mole weight: 1449.25. | |
| Vancomycin-[d10] monoacetate salt | Vancomycin-[d10] monoacetate salt is the labelled acetate form of Vancomycin. Vancomycin monoacetate salt exhibits potent activity against Gram-positive bacteria, and high effects against MRSA in vitro and in vivo. It interferes with cell wall synthesis by binding to D-alanine-D-alanine residues. Alternative Names: [D10]-Vancomycin monoacetate salt; D10-Vancomycin monoacetate salt; Vancomycin-d10 monoacetate salt. Grades: >98%. Molecular formula: C68H69D10Cl2N9O26. Mole weight: 1519.38. | |
| Vancomycin-[d12] | Labelled Vancomycin. Vancomycin is a tricyclic glycopeptide antibiotic. It inhibits cell wall synthesis in Gram-positive bacteria. Alternative Names: (1S,2R,18R,19R,22S,25R,28R,40S)-48-[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[[(2R)-4-methyl-2-(methylamino)pentanoyl]amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid-d12. Molecular formula: C66H63D12Cl2N9O24. Mole weight: 1461.33. | |
| Vancomycin EP Impurity A | Vancomycin EP Impurity A is a glycopeptide antibiotic produced by Nocardia orientalis A51568.1. Activity against gram-positive bacteria. Alternative Names: N2.1-demethylvancomycin B; N-Demethyl Vancomycin B; Norvancomycin; A51568 A. Grades: 95%. CAS No. 91700-98-0. Molecular formula: C65H73Cl2N9O24. Mole weight: 1435.22. | |
| Vancomycin hydrochloride | The salt of a glycopeptide antibiotic isolated from amycolatopsis orientalis. Vancomycin hydrochloride exhibits potent activity against Gram-positive bacteria, and high effects against MRSA in vitro and in vivo. It interferes with cell wall synthesis by binding to D-alanine-D-alanine residues. Alternative Names: Vancomycin HCl; Vancomycin Monohydrochloride. Grades: Assay: 900 ug/mg. CAS No. 1404-93-9. Molecular formula: C66H75Cl2N9O24.HCl. Mole weight: 1485.72. | |
| Vanillic acid | Vanillic acid, an oxidized form of vanillin, is a dihydroxybenzoic acid derivative used as a flavoring and scent agent. Uses: Antifungal. Alternative Names: 4-hydroxy-3-methoxybenzoic acid. Grades: > 98 %. CAS No. 121-34-6. Molecular formula: C8H8O4. Mole weight: 168.15. | |
| Vanillin-[methoxy-d3] | Vanillin-[methoxy-d3] is a labelled analogue of Vanillin which is mostly used for flavoring foods. Alternative Names: 4-Hydroxy-3-methoxy-d3 benzaldehyde; Vanillin-d3. Grades: 99% by CP; 99% atom D. CAS No. 74495-74-2. Molecular formula: C8H5D3O3. Mole weight: 155.17. | |
| Vanillylamine-[d3] Hydrochloride | Vanillylamine-[d3] Hydrochloride is a labelled metabolite of Capsaicin. Alternative Names: 4-(Aminomethyl)-2-methoxyphenol-d3 Hydrochloride; 4-Hydroxy-3-methoxybenzylamine-d3 Hydrochloride; 3-Methoxy-d3-4-hydroxybenzylamine Hydrochloride; α-Aminocreosol-d3 Hydrochloride. CAS No. 1217899-51-8. Molecular formula: C8H9D3ClNO2. Mole weight: 192.66. | |
| Vanillylidenacetone | Vanillylidenacetone (CAS# 1080-12-2) is a useful research chemical. Alternative Names: (E)-4-(4-hydroxy-3-methoxyphenyl)but-3-en-2-one. Grades: 98.0%. CAS No. 1080-12-2. Molecular formula: C11H12O3. Mole weight: 192.21. | |
| Varenicline tartrate | Varenicline (trade name Chantix in the USA and Champix in Canada, Europe and other countries, marketed by Pfizer, usually in the form of varenicline tartrate), is a prescription medication used to treat nicotine addiction. Varenicline is a nicotinic receptor partial agonist-it stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms it can assist some patients to quit smoking. Alternative Names: 7;8;9;10-tetrahydro-6H-6;10-methanoazepino[4;5-g]quinoxaline (2R;3R)-2;3-dihydroxysuccinate; Champix (TN); 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene L-tartrate; 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate Champix; CP-526555-18; CP 526555 18; CP52655518; Chantix; Champix. Grades: ≥ 95%. CAS No. 375815-87-5. Molecular formula: C17H19N3O6. Mole weight: 361.35. | |
| (±)-Vasicine | (±)-Vasicine is an alkaloid showing significant anti-secretory, antioxidant and cytoprotective effect. Alternative Names: Peganine; 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol. Grades: 98%. CAS No. 6159-56-4. Molecular formula: C11H12N2O. Mole weight: 188.23. | |
| Vasopressin-[d5] | Vasopressin-[d5] is a labelled analogue of Vasopressin. Vasopressin is a neurohypophysial hormone existing in most mammals. It has the function of regulating body's water retention via antidiuretic activity. Vasopressin is a peptidic V1a receptor agonist that can increase blood pressure by contracting the blood vessels. Alternative Names: Arginine Vasopressin-d5; 19-Amino-13-(benzyl-d5)-7-(carbamoylmethyl)-4-[2-[[1-[(carbamoylmethyl)carbamoyl]-4-guanidinobutyl]carbamoyl]-1-pyrrolidinylcarbonyl]-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide; 3-(Phenylalanine)-8-arginineoxytocin-d5; 8-L-Arginine-vasopressin-d5; AVP-d5; Arg8-vasopressin-d5; Arginine antidiuretic hormone-d5; Arginine-8-vasopressin-d5; Arginine-vasopressin-d5; Argipressin-d5; Leiormone-d5; [8-Arginine]vasopressin-d5; 3-(L-Phenylalanine)-8-L-arginine-oxytocin-d5; Pitressin-d5; Rindervasopressin-d5; L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-arginylglycinamide Cyclic (1→6)-Disulfide-d5. Grades: >98%. CAS No. 1356383-11-3. Molecular formula: C46H60D5N15O12S2. Mole weight: 1089.28. | |
| Vc-seco-DUBA | Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco. Alternative Names: [(1S)-1-(chloromethyl)-3-[6-[(4-hydroxybenzoyl)amino]imidazo[1,2-a]pyridine-2-carbonyl]-9-methyl-1,2-dihydrobenzo[e]indol-5-yl] N-[2-[[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxycarbonylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methoxycarbonyl-methylamino]ethyl]-N-[2-(2-hydroxyethoxy)ethyl]carbamate. CAS No. 1345681-58-4. Molecular formula: C65H75ClN12O17. Mole weight: 1331.81. | |
| Vemurafenib-[d7] | Vemurafenib-[d7] is the labelled analogue of Vemurafenib, which is a B-Raf enzyme inhibitor used for the treatment of late-stage melanoma. Alternative Names: Vemurafenib D7. CAS No. 1365986-73-7. Molecular formula: C23H11D7ClF2N3O3S. Mole weight: 496.97. | |
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