BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| L-Fucose-BSA |  | |
| L-Fuculose - Aqueous solution | L-Fuculose - A Revolutionary Aqueous Elixir is an awe-inspiring bioactive compound used to study diabetes, where its antioxidant and anti-inflammatory prowess form an indomitable alliance. Synonyms: L-fuculose; 13074-08-3; 6-deoxy-L-tagatose; L-Tagatose, 6-deoxy-; L-Fuculose (1M in Water); (3R,4R,5S)-1,3,4,5-tetrahydroxyhexan-2-one; L-Fuculose Open Form; 6-deoxy-L-lyxo-hex-2-ulose; fuculose; 6-deoxy L-tagatose; SCHEMBL12189710; CHEBI:17617; QZNPNKJXABGCRC-LFRDXLMFSA-N; AKOS030254823; C01721; Q3047391; CVU. CAS No. 13074-08-3. Molecular formula: C6H12O5. Mole weight: 164.16. | |
| L-Galactono-1,4-lactone | L-Galactono-1,4-lactone is a fundamental compound extensively utilized with sector assuming a pivotal position. Its application encompasses the synthesis of ascorbate, popularly known as vitamin C, within the cellular frameworks of both plants and animals. Synonyms: L-Galactonic acid gamma-lactone. CAS No. 1668-08-2. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| L-Galactose-1-phosphate | L-Galactose-1-phosphate is a crucial substrate in the pentose phosphate pathway and a precursor for the synthesis of L-ascorbic acid (vitamin C). It plays a significant role in studying diseases caused by vitamin C deficiency. Synonyms: 1-O-phosphono-L-galactopyranose; L-galactopyranose-1-(dihydrogen phosphate). Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| L-Galactose-6-O-sulphate sodium salt | L-Galactose-6-O-sulphate sodium salt is a crucial compound used in the research of various diseases, particularly those related to carbohydrate metabolism. With its unique properties, this product aids in studying specific enzymes or chemical pathways involved in certain diseases. Molecular formula: C6H11O9SNa. Mole weight: 282.20. | |
| L-Galacturonic acid | L-Galacturonic acid is a vital component widely used in the production of pharmaceutical drugs, serving as a key ingredient in the research of various diseases. CAS No. 108729-78-8. | |
| LGB-321 HCl | The hydrochloride salt form of LGB-321, a picolinamide derivative, has been found to be a PIM kinases inhibitor that could influence the proliferation of sorts of cell lines related to some hematological malignancies. Synonyms: LGB321 HCl; LGB 321 HCl. Grades: 98%. CAS No. 1469925-36-7. Molecular formula: C23H24Cl2F3N5O2. Mole weight: 530.37. | |
| LGD-4665 | LGD-4665, an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and potent agonist of the TPO receptor and therefore induces differentiation and proliferation of megakaryocytes. The pharmacologic characteristics indicate potential therapeutic use in thrombocytopenic patients with a variety of clinical etiologies. Research demonstrated that LGD-4665 was well-tolerated with an excellent safety profile. Multiple phase-II studies in thrombocytopenic patients due to ITP, Hep-C and MDS with daily and weekly dosing regimens, as well as additional Phase-I pharmacology studies in healthy volunteers are underway. Synonyms: LGD-4665; LGD 4665; LGD4665. CAS No. 1192571-53-1. | |
| LGK974 | LGK974 is a selective and orally bioavailable Porcupine inhibitor under development for the treatment of cancers that are driven by the Wnt pathway in a Wnt ligand-dependent manner. LGK974 was shown to induce tumor regression in a Wnt-driven murine tumor model. Synonyms: LGK-974; WNT-974; 2-(2',3-Dimethyl-[2,4'-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide; 2-[5-methyl-6-(2-methylpyridin-4-yl)pyridin-3-yl]-N-(5-pyrazin-2-ylpyridin-2-yl)acetamide. Grades: >98%. CAS No. 1243244-14-5. Molecular formula: C23H20N6O. Mole weight: 396.454. | |
| L-Gluconic acid calcium salt | L-Gluconic acid calcium salt is a scientifically advanced creation, used for studying insufficient calcium levels and enhance skeletal vitality. It functions as an indispensable calcium adjunct aiding in the research of osteoporosis. Synonyms: Calcium L-gluconate. CAS No. 152772-65-1. Molecular formula: C6H11O7 Ca. Mole weight: 215.19. | |
| L-Glucono-1,4-lactone | L-Glucono-1,4-lactone is renowned for its versatility in biomedical applications, serving as an acidifier in beverages and a pivotal Vitamin C precursor. Remarkably, its application extends to the research of liver diseases, alzheimer's and cancer. Synonyms: L-Glucono-gamma-lactone; 74464-44-1; L-glucono-1,4-lactone; Glucono-gamma-lactone, L-; B127M65W5J; (3S,4S,5S)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one; (3S,4S,5S)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one; (3S,4S,5S)-5-((1S)-1,2-Dihydroxyethyl)-3,4-dihydroxy-tetrahydrofuran-2-one; UNII-B127M65W5J; L-Gluconic acid, gamma-lactone; SCHEMBL5919577; L-GLUCONO-.GAMMA.-LACTONE; AKOS040752556; L-GLUCONIC ACID. GAMMA.-LACTONE. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| L-Glucono-1,5-lactone | L-Glucono-1,5-lactone, a fundamental constituent within the biomedical sector, assumes an essential role as a precursor for manufacturing L-ascorbic acid (commonly referred to as Vitamin C). Synonyms: L-Gluconic acid d-lactone. CAS No. 52153-09-0. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| L-Glucose | L-Glucose is a profoundly pivotal bioactive compound, propelling cutting-edge research in the intricate domain of diabetes. Unraveling the intricacies of glucose metabolism and orchestrating the intricate dance of insulin signaling pathways, this resplendent compound bequeaths profound scientific revelations. CAS No. 921-60-8. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| L-Glucuronic acid sodium salt | L-Glucuronic acid sodium salt is an indispensable biomedical substance renowned for its applications in studying liver ailments and expediting detoxification mechanisms. Synonyms: Sodium L-glucuronate. Molecular formula: C6H9NaO7. Mole weight: 216.12. | |
| L-Glycero-D-gluco-heptose | L-Glycero-D-gluco-heptose is an indispensable compound, showcasing multifaceted applicability across diverse research domains, including diabetes, cancer and cardiovascular disorders. Synonyms: b-L-Galactoheptose. CAS No. 84142-51-8. Molecular formula: C7H14O7. Mole weight: 210.18. | |
| L-Glycero-D-manno-heptose | L-Glycero-D-manno-heptose is a crucial molecule widely used in the biomedical industry. Known for its unique structure, it acts as a precursor in the synthesis of lipopolysaccharides (LPS) found in the cell walls of various bacteria. This compound is vital for the development of therapeutic agents targeting bacterial infections and testing vaccines against diseases caused by gram-negative bacteria. CAS No. 4305-74-2. Molecular formula: C7H14O7. Mole weight: 210.18. | |
| L-Glycero-D-manno heptose peracetate | | |
| L-Glycero-L-galacto-heptose | L-Glycero-L-galacto-heptose is a crucial compound used for various applications. It plays a significant role in the development of potential drugs to study chronic diseases like cancer and diabetes. Additionally, its unique properties make it a key ingredient in the production of vaccines, assisting in enhancing their effectiveness. Synonyms: a-L-Mannoheptose. CAS No. 20585-65-3. Molecular formula: C7H14O7. Mole weight: 210.2. | |
| L-Gulonic acid-1,4-lactone | L-Gulonic acid-1,4-lactone, the esteemed biochemical precursor essential for the synthesis of life-sustaining ascorbic acid (vitamin C), emerges as a paramount component. Synonyms: L-Gulonic-gamma-lactone; L-Gulonolactone. CAS No. 1128-23-0. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| L-Gulurono-6,3-lactone | L-Gulurono-6,3-lactone is a vital constituent in mammalian L-ascorbic acid (Vitamin C) biosynthesis. Its biomedical utility prevails prominently, studying Vitamin C deficiency, scurvy and sundry ailments associated with insufficient Vitamin C levels. Synonyms: L-Gulofurano-6,3-lactone; L-Gulofuranuronic acid gamma-lactone. CAS No. 14474-04-5. Molecular formula: C6H8O6. Mole weight: 176.12. | |
| Liarozole | This active molecular has a potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits P450-dependent ATRA-4-hydroxylase to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. Meanwhile, liarozole also inhibits aromatase that catalyzes estrogen biosynthesis in rating-limited step. In Aug 2005, clinical development was ongoing for Ichthyosis in Europe.In Jan 2006, Phase-II/III clinical trials in Ichthyosis was ongoing in Europe and in Canada. Uses: Treatment for ichthyosis. Synonyms: 6-[(3-chlorophenyl)-imidazol-1-ylmethyl]-1H-benzimidazole, R 75251; R-75251; R75251. Grades: 98%. CAS No. 115575-11-6. Molecular formula: C17H13ClN4. Mole weight: 308.771. | |
| Liarozole dihydrochloride | Liarozole dihydrochloride is a cytochrome P450 inhibitor. It displays antitumor activity against androgen-dependent and independent rat prostate carcinomas. Synonyms: 5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1883548-96-6. Molecular formula: C17H13ClN4.2HCl. Mole weight: 381.69. | |
| Liarozole hydrochloride | Liarozole is a benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits cytochrome P450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, resulting in an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. This agent also inhibits aromatase, the enzyme that catalyzes the final, rate-limiting step in estrogen biosynthesis. Synonyms: Liarozole HCl; R75251 (hydrochloride); 5-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole hydrochloride. CAS No. 145858-50-0. Molecular formula: C17H14Cl2N4. Mole weight: 345.23. | |
| Licofelone | Licofelone is a dual inhibitor of COX-1/COX-2 and 5-lipoxygenase. Uses: Lipoxygenase inhibitors. Synonyms: ML 3000; ML3000; ML-3000; 6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic acid. CAS No. 156897-06-2. Molecular formula: C23H22ClNO2. Mole weight: 379.9. | |
| L-Idaric acid | L-Idaric acid is a promising compound for biomedical applications in research of microbial invasions, assuming a prominent role as the chief constituent in studying a diverse gamut of afflictions, ranging from bacterial infections to fungal maladies. Synonyms: L-idaric acid; 80876-58-0; Discontinued See I164930; (2R,3S,4S,5R)-2,3,4,5-tetrahydroxyhexanedioic acid; SCHEMBL15895451; CHEBI:21333; W-203842; Q27109388. CAS No. 80876-58-0. Molecular formula: C6H10O8. Mole weight: 210.14. | |
| L-Idaric acid 1,4-lactone | L-Idaric acid 1,4-lactone, an esteemed biomedicine with a myriad of applications, unveils its profound therapeutic prowess in the vast realm of medical science. Renowned for its exquisite antioxidant attributes and tantalizing potential in combating cancer, this compound entices researchers and drug developers alike, beckoning them to unravel its enigmatic therapeutic effects that navigate the intricate labyrinth of specific malignancies and afflictions tormenting the delicate harmony of oxidative stress-induced conditions. Synonyms: L-Idaro-1,4-lactone. CAS No. 80876-59-1. Molecular formula: C6H8O7. Mole weight: 192.12. | |
| L-Iditol | L-Iditol, known as a pharmaceutical excipient and nutrient additive, showcases its versatility in the sphere of medical applications. Its intrinsic stabilizing properties render it a trusted component in tablet and capsule fabrication. Synonyms: L-Iditol; 488-45-9; Iditol; (2S,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol; Hexahydroxyhexane; 1Q2H9GC12E; (2S,3R,4R,5S)-hexane-1,2,3,4,5,6-hexaol; MFCD00064289; Karion; Hexahydric alcohol; L-Idit; IDITOL, L-; L-Iditol, >=98%; UNII-1Q2H9GC12E; SCHEMBL435775; CHEBI:18202; FBPFZTCFMRRESA-UNTFVMJOSA-N; DTXSID901337629; AKOS024258141; AS-56025; HY-121654; CS-0082969; I0725; C01507; D91196; W-202860; Q27102896. CAS No. 488-45-9. Molecular formula: C6H14O6. Mole weight: 182.17. | |
| L-Idonic acid-1,4-lactone | L-Idonic acid-1,4-lactone, a chemical compound with vital biomedical applications, is renowned for its ability to synthesize L-ascorbic acid or vitamin C, a potent micronutrient that functions as a powerful antioxidant in the human body. This compound has tremendous potential to prevent and treat scurvy triggered by vitamin C deficiency. With its multi-faceted therapeutic properties, L-Idonic acid-1,4-lactone stands out as a promising candidate for future research in pharmacology and medicine. CAS No. 1128-24-1. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| L-Idose - Aqueous solution | L-Idose Syrup - Aqueous elixir, an innovative biomedical concoction is an enriching sugar derivative, exhibiting remarkable and auspicious potential in studying an assortment of ailments such as cancer and diabetes. Synonyms: Idose, L-; 5934-56-5; (2R,3S,4R,5S)-2,3,4,5,6-pentahydroxyhexanal; F78BCN2M7Z; aldehydo-L-idose; IDOSE L-FORM [MI]; SCHEMBL16609846; CHEBI:151298; GZCGUPFRVQAUEE-UNTFVMJOSA-N; AKOS027326902; L-Idose-1-13C (0.16M Aqueous Solution); WURCS=2.0/1,1,0/[o2121h]/1/; Q27277756. CAS No. 5934-56-5. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| L-Iduronic acid-1,6-13C2 | L-Iduronic acid-1,6-13C2 is a valuable biochemical utilized in the biomedical industry for its role in synthesizing drugs used to study diseases related to abnormal glycosaminoglycan metabolism. Its isotopic label, 13C2, aids in research and drug development, facilitating accurate tracing and analysis of metabolic pathways. Molecular formula: 13C2C4H10O7. Mole weight: 2523.81. | |
| L-Iduronic acid sodium salt | L-Iduronic acid sodium salt, a highly significant compound prevalent in the biomedical field, finds extensive application. In the pursuit of combating diverse ailments like cancer, cardiovascular diseases, and inflammatory disorders, this compound serves as an indispensable component for drug synthesis. Its remarkable attributes render it crucial for formulating drug delivery systems that augment therapeutic efficacy. Uses: A constituent of certain mucopolysaccharides. Synonyms: Sodium L-iduronate; L-Iduronic acid, monosodium salt; (2R,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate sodium salt. Grades: ≥95%. CAS No. 61199-83-5. Molecular formula: C6H9NaO7. Mole weight: 216.12. | |
| Limiglidole | Limiglidole is used as a antihyperglycaemic drug candidate. It shows antiplatelet activity 2-fold exceeded activity of antiplatelet agent acetylsalicylic acid in the mouse model of systemic collagen-epinephrine thrombosis. It significantly decreased the relative and mean area of blood clots in the sections of mouse lungs. Uses: Limiglidole is used as a antihyperglycaemic drug candidate. Synonyms: 2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)-N,N-diethylethanamine. Grades: 98%. CAS No. 64644-54-8. Molecular formula: C15H22N4. Mole weight: 258.37. | |
| Lin28 1632 | Lin28 1632 is an RNA binding protein Lin28 inhibitor with IC50 value of 8 μM. It can inhibit growth of tumor cell lines and tumor-sphere formation in vitro. Synonyms: Lin28 1632; Lin-28 1632; Lin 28 163; Lin281632; Lin-281632; Lin 281632. N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide. Grades: ≥98% by HPLC. CAS No. 108825-65-6. Molecular formula: C15H15N5O. Mole weight: 281.31. | |
| Linamarin | Linamarin is a renowned chemical compound extensively employed within the biomedical sector for investigatory objectives, taking the lead in the research of specific ailments such as cancer and neurodegenerative disorders. Synonyms: 2-(b-D-Glucopyranosyloxy)-2-methyl-propanenitrile; Phaseolunatin; a-Hydroxyisobutyronitrile b-D-glucose. CAS No. 554-35-8. Molecular formula: C10H17NO6. Mole weight: 247.25. | |
| Lincomycin EP Impurity F | Methyl 1-Thiolincosaminide is an intermediate in the production of biosynthetic antibiotics. Synonyms: Methyl 6-amino-6,8-dideoxy-1-thio-D-erythro-a-D-galacto-octopyranoside; Methyl a-thiolincosaminide. Grades: > 95%. CAS No. 14810-93-6. Molecular formula: C9H19NO5S. Mole weight: 253.32. | |
| Lincosamine | Lincosamine is a multifaceted antimicrobial compound extensively employed within the biomedical sector for researchs of bacterial afflictions, encompassing cutaneous manifestations, respiratory tract invasions and the notorious acne. Synonyms: 6-Amino-6,8-dideoxy-D-erythro-D-galacto-octopyranose. CAS No. 13006-69-4. Molecular formula: C8H17NO6. Mole weight: 223.22. | |
| Liothyronine-acyl-D-glucuronide | Liothyronine-acyl-D-glucuronide is a crucial compound used for studying the metabolisms of liothyronine, a compound used in the research of hypothyroidism. Acting as a metabolite, this compound aids in the understanding of drug interactions, metabolism pathways and potential side effects associated with liothyronine therapy. Molecular formula: C21H20I3NO10. Mole weight: 827.10. | |
| Lipid X | Lipid X is a lipid-lowering compound used for Hyperlipidemia research. Synonyms: a-D-Glucopyranose, 2-deoxy-2-[(3-hydroxy-1-oxotetradecyl)amino]-, 1-(dihydrogen phosphate) 3-(3-hydroxytetradecanoate), [2(R),3(R)]-. CAS No. 86559-73-1. Molecular formula: C34H66NO12P. Mole weight: 711.86. | |
| Lithocholic Acid 3-O-Glucuronide | Lithocholic Acid 3-O-Glucuronide is an impurity of Lithocholic Acid, a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones. Synonyms: (3α,5β)-23-Carboxy-24-norcholan-3-yl β-D-Glucopyranosiduronic Acid; Lithocholic Acid 3-Glucuronide. Grades: 98%. CAS No. 75239-91-7. Molecular formula: C30H48O9. Mole weight: 552.7. | |
| LLL12 | LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration and works synergistically with doxorubicin and gemcitabine. LLL12 demonstrated a potent inhibitory activity on breast and glioblastoma tumor growth in a mouse xenograft model. LLL12 may be a potential therapeutic agent for human cancer cells expressing constitutive STAT3 signaling. Synonyms: LLL12; LLL-12; LLL 12. CAS No. 1260247-42-4. Molecular formula: C14H9NO5S. Mole weight: 303.29. | |
| L-Lyxonic acid potassium salt | L-Lyxonic acid potassium salt is a pivotal compound extensively employed in the biomedical sector, acting as a pivotal constituent in studying for afflictions such as diabetes, cardiovascular diseases, and select cancer variants. Synonyms: Potassium (2R,3R,4S)-2,3,4,5-tetrahydroxypentanoate; L-Lyxonic acid potassium salt. Molecular formula: C5H9KO6. Mole weight: 204.22. | |
| L-Lyxono-1,4-lactone | L-Lyxono-1,4-lactone is a multifaceted compound ubiquitous in the biomedical domain proffering profound benefits across disparate maladies, encompassing malignant neoplasms and viral afflictions. Synonyms: L-Lyxonic Acid γ-Lactone; L-Lyxonic acid 1,4-lactone; (3R,4S,5S)-3,4-Dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one. Grades: ≥97%. CAS No. 104196-15-8. Molecular formula: C5H8O5. Mole weight: 148.11. | |
| L-Lyxosamine | L-Lyxosamine is an indispensible constituent playing an unequivocal role as a cornerstone for synthesizing pharmaceutical compounds. It aids in studying immunosuppressed ailments and malignant infestations. Synonyms: 2-Amino-2-deoxy-L-lyxose. Molecular formula: C5H11NO4. Mole weight: 149.15. | |
| L-Lyxose | L-Lyxose is a valuable carbohydrate utilized in the synthesis of drug development targeting various diseases, including cancer, diabetes and cardiovascular disorders. Synonyms: Lyxose, L-; (2R,3R,4S)-2,3,4,5-tetrahydroxypentanal; aldehydo-L-lyxose; L-Lyx. CAS No. 1949-78-6. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| L-Mannitol | L-Mannitol, a versatile sugar alcohol, has found its way into a plethora of biomedical applications. Exhibiting its potency as an osmotic diuretic, this compound is efficacious against cerebral edema and glaucoma. However, L-Mannitol isn't just a one-trick pony; it has been extensively used as an excipient in various pharmaceutical formulations for optimizing the solubility and stability of drugs. Furthermore, the substance has drawn considerable attention as a promising therapeutic agent unparalleled for addressing cystic fibrosis and diabetes. Synonyms: Mannitol, L-; L-manno-Hexitol. Grades: ≥96%. CAS No. 643-01-6. Molecular formula: C6H14O6. Mole weight: 182.17. | |
| L-Mannonic acid-1,4-lactone | L-Mannonic acid-1,4-lactone, known for its vital role in studying metabolic disorders, acts as a precursor for L-ascorbic acid (commonly known as Vitamin C) synthesis. Its potent antioxidant properties provide an effective shield against detrimental oxidative stress. Synonyms: L-Mannono-1,4-lactone. CAS No. 22430-23-5. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| L-Menthylglucoside | L-Menthylglucoside is an intricately synthesized biomedical compound, esteemed for its inhibitory efficacy in studying diverse dermatological ailments such as xeroderma, dermatitis and plaque psoriasis. This multifaceted substance is endowed with potent antioxidative and anti-inflammatory attributes. Synonyms: (-)-Menthyl O-b-D-glucopyranoside; (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl b-D-glucopyranoside. CAS No. 16203-27-3. Molecular formula: C16H30O6. Mole weight: 318.41. | |
| LMI070 | LMI070, also called as NVS-SM1, is a selective, high plasma exposure and orally active modulator of SMN2 splicing which demonstrates robust activity across disease-relevant induced pluripotent stem cell (iPSc)-derived neurons. in vivo: oral administration. Synonyms: (6E)-3-(1H-pyrazol-4-yl)-6-[3-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-1H-pyridazin-6-ylidene]cyclohexa-2,4-dien-1-one; UNII-P12R69543A; P12R69543A; Branaplam; Branaplam [INN]; SCHEMBL15475826; LMI-070; LMI 070; LMI070; 1562338-42-4; Phenol, 5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetra. CAS No. 1562338-42-4. Molecular formula: C22H27N5O2. Mole weight: 393.48. | |
| L-Moses | L-Moses is a selective inhibitor and a probe of PCAF bromodomain. It inhibits histone H3.3 binding to PCAF bromodomain selectively in HEK-293 cells. Its bioactivity in vivo is being studied. Uses: Probe. Synonyms: Zinc(2+), tris(octamethylpyrophosphoramide)-, diperchlorate; Zinc perchlorate compd. with octamethylpyrophosphoramide (1:3); Pyrophosphoramide, octamethyl-, compd. with zinc perchlorate (3:1); Perchloric acid, zinc salt, compd. with 3 moles of octamethyl pyrophosphoramide; Zinc(2+), tris(octamethyldiphosphoramide-Op,Op')-, (OC-6-11), diperchlorate. CAS No. 15713-67-4. Molecular formula: C24H72Cl2N12O17P6Zn. Mole weight: 1123.03. | |
| L-Noradrenaline | Norepinephrine is the US name for noradrenaline, a catecholamine with multiple roles including as a hormone and a neurotransmitter. It performs its action by being released into the synaptic cleft, where it acts on adrenergic receptors, followed by the signal termination, either by degradation of norepinephrine, or by uptake by surrounding cells. Uses: Adrenergic alpha-agonists. Synonyms: (R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol; l-Arterenol; (-)-α-(Aminomethyl)-3,4-dihydroxy-benzyl Alcohol; 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol; (-)-Arterenol; (-)-Noradrenaline; (-)-Norepinephrine; (-)-α-(Aminomethyl)protocatechuyl Alcohol; (R)-(-)-Norepinephrine; (R)-Noradrenaline; (R)-Norepinephrine; Adrenor; Aktamin; Arterenol; Levarterenol; Levoarterenol; Levonor; Levonoradrenaline; Levonorepinephrine; Levophed; Nor-Epirenan; Noradrenalin; Noradrenaline; Norartrinal; Norepinephrine; Norepirenamine; Sympathin E; l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol; l-2-Amino-1-(3,4-dihydroxyphenyl)ethanol; l-3,4-Dihydroxyphenylethanolamine; l-Arterenol; l-Noradrenaline; l-Norepinephrine; l-α-(Aminomethyl)-3,4-dihydroxybenzyl Alcohol. Grades: >98%. CAS No. 51-41-2. Molecular formula: C8H11NO3. Mole weight: 169.18. | |
| L-Noviose | L-Noviose is an extraordinary pharmaceutical compound, aiding in studying viral infections encompassing influenza and herpes. Daringly disruptive, L-Noviose bids adieu to infection dissemination by resolutely thwarting viral DNA synthesis. CAS No. 107739-83-3. | |
| Lombazole | Lombazole is used as an antimicrobial agent of the imidazole class. Uses: Lombazole is used as an antimicrobial agent of the imidazole class. Synonyms: Bay h 6020; Lombazolum; Lombazol; 1-([1,1'-biphenyl]-4-yl(2-chlorophenyl)methyl)-1H-imidazole; (2-Chlorophenyl)-imidazol-1-yl-(biphenyl-4-yl)methane. Grades: 98%. CAS No. 60628-98-0. Molecular formula: C22H17ClN2. Mole weight: 344.84. | |
| Lometrexol | Lometrexol is a folate analog antimetabolite with antineoplastic activity. As the 6R diastereomer of 5,10-dideazatetrahydrofolate, lometrexol inhibits glycinamide ribonucleotide formyltransferase (GARFT), the enzyme that catalyzes the first step in the de novo purine biosynthetic pathway, thereby inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation. The agent has been shown to be active against tumors that are resistant to the folate antagonist methotrexate. Uses: Antimetabolites, antineoplastic. Synonyms: Lometrexol; LMTX; LY 264618; LY-264618; LY264618. CAS No. 106400-81-1. Molecular formula: C21H25N5O6. Mole weight: 443.46. | |
| Lometrexol disodium | Lometrexol is a folate analog antimetabolite with antineoplastic activity. Synonyms: LY 264618 disodium; LY264618 disodium; NSC-722969; NSC 722969; L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-, disodium salt. Grades: 98%. CAS No. 120408-07-3. Molecular formula: C21H23N5Na2O6. Mole weight: 487.42. | |
| Lonaprisan | Cas No. 211254-73-8. | |
| lonoctocog alpha | lonoctocog alpha is a recombinant and single-chain antihemophilic factor approved for the treatment of bleeding episodes in patients with hemophilia A. Main indications are to reduce the number of bleeding episodes and to lower the risk of joint damage due to bleeding. Uses: The treatment of bleeding episodes in patients with hemophilia a. Synonyms: Afstyla. | |
| Loracarbef | Loracarbef is an antibiotic originated by Kyowa Hakko. It is a synthetic carbacephem analogue of cefaclor, and is more stable chemically. But Its use was discontinued in 2006. Uses: Bacterial infections. Synonyms: (6R,7S)-7-[[(2R)-2-Amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Lorabid. Grades: 98%. CAS No. 76470-66-1. Molecular formula: C16H16ClN3O4. Mole weight: 349.77. | |
| Lorglumide sodium | Lorglumide sodium is a potent and selective cholecystokinin A (CCKA) antagonist. CCKA is a peptide hormone of the gastrointestinal system that promotes fat and protein digestion. Lorglumide is used as a drug suppressing gastrointestinal motility and reducing gastric secretions. Synonyms: Lorglumide sodium salt; 4-[(3,4-dichlorobenzoyl)amino]-5-(dipentylamino)-5-oxopentanoate sodium. Grades: ≥98%. CAS No. 1021868-76-7. Molecular formula: C22H31Cl2N2O4·Na. Mole weight: 481.4. | |
| Losartan N1-Glucuronide | Losartan N1-Glucuronide is a metabolite of Losartan. Synonyms: 1-[5-[4-[[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl][1,1-biphenyl]-2-yl]-1H-tetrazol-1-yl]-1-deoxy-b-D-glucopyranuronic acid. Grades: > 95%. CAS No. 138584-34-6. Molecular formula: C28H31ClN6O7. Mole weight: 599.03. | |
| Losartan N2-Glucuronide | Losartan N2-Glucuronide is a metabolite of Losartan. Synonyms: 1-[5-[4'-[[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl][1,1'-biphenyl]-2-yl]-2H-tetrazol-2-yl]-1-deoxy-β-D-Glucopyranuronic Acid; L 158783. Grades: > 95%. CAS No. 138584-35-7. Molecular formula: C28H31ClN6O7. Mole weight: 599.03. | |
| Losoxantrone | Losoxantrone is a DNA intercalator that was developed with the potential to replace anthracyclines. Losoxantrone is also a bioreductive drugs. In phase II trials, losoxantrone demonstrated a partial biochemical response rate of 25%, response in measurable disease sites in 22%, and improvement in clinical symptoms in one-third of patients. Uses: Antineoplastic agents. Synonyms: Biantrazole; CI-941; CI 941; CI941; DuP-941;DuP 941; DuP941; 7-Hydroxy-2-[2- (2-hydroxyethylamino) ethyl]-5-[2- (2-hydroxyethylamino) ethylamino]anthra[1, 9-cd]pyrazol-6 (2H) -one. CAS No. 88303-60-0. Molecular formula: C22H27N5O4. Mole weight: 425.49. | |
| Lotaustralin | Lotaustralin, a naturally occurring compound discovered across diverse plant species, manifests noteworthy anti-inflammatory and analgesic attributes through its adept regulation of pivotal biochemical pathways. Extensive investigations have illuminated Lotaustralin's therapeutic potential in combatting an array of ailments, encompassing cancer and neurodegenerative disorders. Synonyms: 2-(b-D-Glucopyranosyloxy)-2-methylbutyronitrile. CAS No. 534-67-8. Molecular formula: C11H19NO6. Mole weight: 261.27. | |
| Loxistatin Acid | Cas No. 76684-89-4. | |
| LOXO-101 (ARRY-470) | LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. Synonyms: Larotrectinib; ARRY 470; LOXO 101; (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide. Grades: 98%. CAS No. 1223403-58-4. Molecular formula: C21H22F2N6O2. Mole weight: 428.44. | |
| LP-261 | LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. Screening in the NCI60 cancer cell lines resulted in a mean GI50 of approximately 100 nM. LP-261 is a very potent inhibitor of angiogenesis, preventing microvessel outgrowth in the rat aortic ring assay and HUVEC cell proliferation at nanomolar concentrations. Complete inhibition of tumor growth was achieved in the PC3 xenograft model and shown to be schedule dependent. Excellent inhibition of tumor growth in the SW620 model was observed, comparable with paclitaxel. Combining oral, low dose LP-261 with bevacizumab led to significantly improved tumor inhibition. Oral LP-261 is very effective at inhibiting tumor growth in multiple mouse xenograft models and is well tolerated. Synonyms: LP261; LP 261. Grades: 99%. CAS No. 915412-67-8. Molecular formula: C22H19N3O4S. Mole weight: 421.47. | |
| L-Psicose | L-Psicose, the naturally-occurring monosaccharide paramount in the biomedical field, garners significant attention owing to its extensive exploration in the realm of diabetes management, obesity reduction, and dental caries prevention. Moreover, its involvement as a substitute sweetener in an array of consumables further stems from its remarkably diminished caloric composition and marginal influence on glycemic indices. Synonyms: Psicose, L-; L-Allulose; L-ribo-2-Hexulose. Grades: ≥95%. CAS No. 16354-64-6. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| LQB-118 | LQB-118 is an orally active pterocarpanquinone molecule with potential anticancer activity. LQB-118 may have potential therapeutic value for leukemia, being able to overcome multiple resistance mechanisms. Synonyms: LQB-118; LQB 118; LQB118. CAS No. 1219104-20-7. Molecular formula: C19H12O4. Mole weight: 304.30. | |
| L-Quisqualic acid | L-Quisqualic acid is a glutamate receptor agonist acting at AMPA receptors and mGluR positively linked to phosphoinositide hydrolysis. L-Quisqualic acid was shown to induce a slow K(+)-current response in B6 neurons of Aplysia buccal ganglia. It exhibits neuroprotective property and may be beneficial for prostate cancer therapy. Synonyms: (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid; (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid. Grades: ≥99% by HPLC. CAS No. 52809-07-1. Molecular formula: C5H7N3O5. Mole weight: 189.13. | |
| L-Rhamnal | | |
| L-Rhamnopyranose monohydrate | L-Rhamnopyranose monohydrate is a carbohydrate commonly found in plants. It has been studied for its potential use in developing drugs to treat inflammation, cancer, and infectious diseases. Additionally, it has been used in the food and cosmetic industries as a sweetening agent and emulsifier. Synonyms: L-Rhamnose monohydrate; alpha-L-Rhamnose monohydrate; (2R,3R,4R,5R,6S)-6-methyloxane-2,3,4,5-tetrol; hydrate; (2R,3R,4R,5R,6S)-6-methyltetrahydro-2H-pyran-2,3,4,5-tetraol hydrate; MFCD00071591; alpha-L-Mannopyranose, 6-deoxy-, hydrate (1:1); Rhamnopyranose, monohydrate, alpha-L- (8CI); alpha-L-Mannopyranose, 6-deoxy-, monohydrate (9CI); alpha-L-Rhamnopyranose monohydrate; alpha-L-Rhamnose monohydrate; -L-Rhamnose monohydrate; L-Rhamnose monohydrate, 99%; L-Rhamnose monohydrate, >=99%; HY-N0642; s3887; AKOS015965149; CCG-266442; CS-8163; AC-20298; AC-34714; AS-35146; a-L-Mannopyranose, 6-deoxy-, monohydrate; a-L-Mannopyranose, 6-deoxy-,monohydrate (9CI); L-Rhamnose monohydrate, for microbiology, >=99.0%; (2R,3R,4R,5R,6S)-6-methyltetrahydro-2H-pyran-2,3,4,5-tetraolhydrate. CAS No. 6155-35-7. Molecular formula: C6H14O6. Mole weight: 182.172. | |
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