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| Product | Description | |
|---|---|---|
| Norlobariol methyl ester | Norlobariol methyl ester. |  |
| Normiriquidic acid | Normiriquidic acid is a lichen depside. CAS No. 105705-30-4. Molecular formula: C24H28O8. Mole weight: 444.47. | |
| Nornidulin | A depsidone produced by several fungal species; has potent and selective antibacterial activity; has potential as an anti-inflammatory agent. Alternative Names: Ustin; 2,4,7-Trichloro-3,8-dihydroxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo(b,E)(1,4)dioxepin-11-one. Grades: >99% by HPLC. CAS No. 33403-37-1. Molecular formula: C19H15Cl3O5. Mole weight: 429.68. | |
| Nornotatic acid | Nornotatic acid. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 3,8-dihydroxy-1,4,6-trimethyl-11-oxo-; 3,9-dihydroxy-1,7,10-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid. CAS No. 50489-46-8. Molecular formula: C17H14O7. Mole weight: 330.29. | |
| Norobtusatic acid | Norobtusatic acid. Alternative Names: Benzoic acid, 2,4-dihydroxy-3,6-dimethyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester. CAS No. 56410-27-6. Molecular formula: C17H16O7. Mole weight: 332.30. | |
| Norpannarin | It is a depsidone that shows to co-occur with nordechloropannarin, pannarin and argopsin in Lichen Genus Erioderma chilense. CAS No. 103805-90-9. Molecular formula: C17H13ClO6. Mole weight: 348.74. | |
| Norplicacetin | It is originally isolated from Str. plicatus NCIB 11305. And it has the effect of anti-gram-positive bacteria and mycobacterium. Molecular formula: C24H33N5O7. Mole weight: 503.55. | |
| Norvicanicin | Norvicanicin. Alternative Names: 2,8-dichloro-3,9-dihydroxy-1,4,7,10-tetramethylbenzo[b][1,4]benzodioxepin-6-one; 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,7-dichloro-3,8-dihydroxy-1,4,6,9-tetramethyl-. CAS No. 61852-12-8. Molecular formula: C17H14Cl2O5. Mole weight: 369.20. | |
| Nosiheptide | Nosiheptide is a thiopeptide antibiotic produced by Streptomyces actuosus. It has broad spectrum antibacterial activity. Alternative Names: Nosiheptine; Multhiomycin; Primofax; RP 9671. Grades: 90%. CAS No. 56377-79-8. Molecular formula: C51H43N13O12S6. Mole weight: 1222.36. | |
| Notatic acid | Notatic acid. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-1,4,6-trimethyl-11-oxo-; 8-Hydroxy-3-methoxy-1,4,6-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid; Notatinsaeure; Notaticaciol. CAS No. 38636-86-1. Molecular formula: C18H16O7. Mole weight: 344.32. | |
| Nothramicin | It is an anthracycline antibiotic with anti-mycobacterial activity produced by the strain of Nocardia sp. MJ 896-43F. Alternative Names: 3,4,10,12-tetrahydroxy-2,7-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)-3-methylhexopyranoside. Grades: >95%. CAS No. 205752-47-2. Molecular formula: C30H37NO11. Mole weight: 587.61. | |
| Notoginsenoside R1 | Notoginsenoside R1 is a natural triterpenoid compound found in the roots of Panax notoginseng (Burk.)F.H.Chen. Notoginsenoside R1 exhibits antioxidant and antiapoptotic activities. Notoginsenoside R1 provides cardioprotection against ischemia / reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells. Uses: Antioxidant;antiapoptotic. Alternative Names: Dammarane β-D-Glucopyranoside deriv.; Sanqi Glucoside R1; Sanchinoside R1; (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside. Grades: 98%. CAS No. 80418-24-2. Molecular formula: C47H80O18. Mole weight: 933.15. | |
| Novobiocin | Novobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the interaction of both p23 and Hsp70 co-chaperones with the Hsp90 complex. (IC50=700μmol/L). Alternative Names: Streptonivicin; Inamycin; Albamycin; Cathomycin; Cardelmycin; Spheromycin; Antibiotic PA-93; Novobiocina; Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-. Grades: >95%. CAS No. 303-81-1. Molecular formula: C31H36N2O11. Mole weight: 612.62. | |
| NS | NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase. | |
| NS-5 | NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32. | |
| NSC 23766 trihydrochloride | NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Alternative Names: NSC 23766 (trihydrochloride); NSC23766 (trihydrochloride); NSC-23766 (trihydrochloride); N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride. Grades: ≥98%. CAS No. 1177865-17-6. Molecular formula: C24H38Cl3N7. Mole weight: 530.967. | |
| NT-2 | NT-2 is a toxin produced by Fusarium sporotrichioides M-1. Molecular formula: C19H26O8. Mole weight: 382.4. | |
| NT-3 | NT-3 is a toxin produced by Fusarium sporotrichioides M-1. Molecular formula: C17H24O7. Mole weight: 340.37. | |
| Nudicaucin A | Nudicaucin A is a triterpenoid compound found in the Hedyotis nudicaulis. Alternative Names: (3beta)-3-[(3-O-beta-D-Galactopyranosyl-alpha-L-arabinopyranosyl)oxy]-30-noroleana-12,20(29)-dien-28-oic acid beta-D-glucopyranosyl ester. Grades: >98%. CAS No. 211815-97-3. Molecular formula: C46H72O17. Mole weight: 897.07. | |
| Nudicaucin B | Nudicaucin B is a triterpenoid compound found in the Hedyotis nudicaulis. Alternative Names: (3beta)-3-[(3-O-beta-D-Galactopyranosyl-alpha-L-arabinopyranosyl)oxy]-olean-12-en-28-oic acid beta-D-glucopyranosyl ester. Grades: >98%. CAS No. 211557-36-7. Molecular formula: C47H76O17. Mole weight: 913.11. | |
| NVP-HDM201 | NVP-HDM201 (HDM201) is a potent and highly specific MDM-2/p53 inhibitor that binds to human Mdm2 protein with a sub-nanomolar Ki value, activates p53 and induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells. Alternative Names: Siremadlin; HDM201; HDM 201; HDM-201; NVP-HDM-201; NVP-HDM 201. CAS No. 1448867-41-1. Molecular formula: C26H24Cl2N6O4. Mole weight: 555.41. | |
| NVS-PAK1-1 | NVS-PAK1-1 is potent and specific allosteric PAK1 inhibitor (IC50 = 5 nM) with selective over PAK2 and a panel of 442 kinases. Alternative Names: NVS-PAK1-1; NVSPAK11; NVS PAK1 1; (3S)-3-[[8-chloro-11-(2,2-difluoroethyl)-3-fluorobenzo[b][1,4]benzodiazepin-6-yl]amino]-N-propan-2-ylpyrrolidine-1-carboxamide. CAS No. 1783816-74-9. Molecular formula: C23H25ClF3N5O. Mole weight: 479.93. | |
| Nybomycin | An unusual heterocyclic metabolite isolated from several streptomyces species; possesses antiviral and antibacterial activity. Alternative Names: NSC613948; 8-(Hydroxymethyl)-6,11-dimethyl-2H,4H-oxazolo[5,4,3-ij]pyrido[3,2-g]quinoline-4,10(11H)-dione; 8,9-Dihydro-4-(hydroxymethyl)-6,9-dimethyl-2,8-dioxopyrido(3,2-g)quinoline-1(2H)-carboxaldehyde. Grades: >95% by HPLC. CAS No. 30408-30-1. Molecular formula: C16H14N2O4. Mole weight: 298.29. | |
| OA-6129 A | OA-6129 A is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Alternative Names: Antibiotic OA 6129A; OA 6129A; OA-6129A. CAS No. 82475-11-4. Molecular formula: C20H31N3O7S. Mole weight: 457.5. | |
| OA-6129 B1 | OA-6129 B1 is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Alternative Names: Antibiotic OA 6129B1; OA 6129B1; OA-6129B1. Molecular formula: C20H31N3O8S. Mole weight: 473.5. | |
| OA-6129 B2 | OA-6129 B2 is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Alternative Names: Antibiotic OA 6129B2; OA 6129B2; OA-6129B2. CAS No. 82475-10-3. Molecular formula: C20H31N3O8S. Mole weight: 473.5. | |
| OA-6129 C | OA-6129 C is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Alternative Names: Antibiotic OA 6129C; OA 6129C; OA-6129C. Molecular formula: C20H31N3O11S2. Mole weight: 553.6. | |
| OA-6129 D | OA-6129 D is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. It is also effective against dehydrodipeptidase and Comamonas terrigena B-996. Alternative Names: Antibiotic OA 6129D; OA 6129D; OA-6129D. CAS No. 85414-25-1. Molecular formula: C20H33N3O8S. Mole weight: 475.6. | |
| OA-6129 E | OA-6129 E is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. It is also effective against dehydrodipeptidase and Comamonas terrigena B-996. Alternative Names: Antibiotic OA 6129E; OA 6129E; OA-6129E. CAS No. 85414-26-2. Molecular formula: C21H35N3O8S. Mole weight: 489.6. | |
| O-Acetylbenzeneamidinocarboxylic acid | O-Acetylbenzeneamidinocarboxylic acid is isolated from Gibberella saubinetii with antitumor activity. It has weak inhibitory effect on tumor cells. Alternative Names: Acetic acid, 2-[(2-acetylphenyl)amino]-2-imino-; [(2-Acetylphenyl)amino](imino)acetic acid. Grades: ≥95%. CAS No. 82744-16-9. Molecular formula: C10H10N2O3. Mole weight: 206.20. | |
| O-Acetylcrinipellin A | It is produced by the strain of Crinipellis stipitaria. It has anti-gram-positive bacteria and Aldrin ascites carcinoma activity. Alternative Names: Acetylcrinipellin A; Crinipellin; Crinipellin A acetate; 7a,9a-dimethyl-3-methylidene-2,9-dioxo-7-(propan-2-yl)decahydro-1aH,5H-pentaleno[6a',1':5,6]pentaleno[1,6a-b]oxiren-8-yl acetate. CAS No. 97315-00-9. Molecular formula: C22H28O5. Mole weight: 372.46. | |
| Obscurolide A1 | Obscurolide A1 is a weak phosphodiesterase inhibitor isolated from Streptomyces viridochromogenes. Alternative Names: 4-[[2-[(E)-3-hydroxybut-1-enyl]-5-oxooxolan-3-yl]amino]benzoic acid. Grades: ≥98%. CAS No. 144397-99-9. Molecular formula: C15H17NO5. Mole weight: 291.30. | |
| O-Carbamoyl-D-serine | O-Carbamoyl-D-serine is an antibiotic produced by Str. polychromogenes. It can inhibit the synthesis of bacterial cell wall and has weak anti-gram-positive bacteria activity. Molecular formula: C4H8N2O4. Mole weight: 148.12. | |
| Ochracenomicin A | It is produced by the strain of Amicolatopsis sp. MJ 950-891. Ochracenomicin A has a strong effect against gram-positive bacteria (including MRSA strain), and also against gram-negative bacteria and candida albicans. Alternative Names: 4a,8,12b-trihydroxy-3-methyl-3,4,4a,12b-tetrahydrotetraphene-1,7,12(2H)-trione. Molecular formula: C19H16O6. Mole weight: 340.33. | |
| Ochracenomicin C | It is produced by the strain of Amicolatopsis sp. MJ 950-891. Ochracenomicin C has a weak antibacterial effect. Molecular formula: C19H20O5. Mole weight: 328.36. | |
| Ochratoxin B | Ochratoxin B is an analogue of Ochratoxin A. Ochratoxins are mycotoxins produced by Aspergillus and Penicillium. Grades: >99% by HPLC. CAS No. 4825-86-9. Molecular formula: C20H19NO6. Mole weight: 369.37. | |
| Ochratoxin C | A minor component of the ochratoxin complex produced by Aspergillus orchraceus and penicillium sp. It is a mycotoxin associated with food spoilage. It is the ethyl ester of ochratoxin A and represents a different hazard to the acidic major components ochratoxins A and B. Alternative Names: Ochratoxin A ethyl ester; ethyl ((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochromane-7-carbonyl)-L-phenylalaninate; L-Phenylalanine, N-((5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-, ethyl ester, (R)-; N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine, ethyl ester. Grades: >95% by HPLC. CAS No. 4865-85-4. Molecular formula: C22H22ClNO6. Mole weight: 431.87. | |
| Octacosamicin A | Octacosamicin A is originally isolated from Amycolatops azurea MG 398-hF9 (FERM P-8865). It has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak. Alternative Names: Antibiotic MG 398HF9A; Glycine, N-(28-((aminoiminomethyl)hydroxyamino)-2,3,5,7-tetrahydroxy-1,19-dioxo-12,14,20,22-octacosatetraenyl)-. Grades: >95%. CAS No. 122005-25-8. Molecular formula: C31H52N4O9. Mole weight: 624.76. | |
| Octacosamicin B | Octacosamicin B is originally isolated from Amycolatops azurea MG 398-hF9 (FERM P-8865). It has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak. CAS No. 122005-24-7. Molecular formula: C32H54N4O9. Mole weight: 638.79. | |
| Octadecanoyl-L-homoserine lactone | An active quorum sensing modulator first recognised in sinorhizobium meliloti. Alternative Names: C18-HSL; N-Octadecanoyl-L-homoserine lactone; N-(2-oxooxolan-3-yl)octadecanamide; N-stearoyl-L-homoserine lactone; C18-L-HSL; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octadecanamide. Grades: >99% by HPLC. CAS No. 479050-96-9. Molecular formula: C22H41NO3. Mole weight: 367.57. | |
| Octanoyl-L-homoserine lactone | An active quorum sensing modulator first recognised in yersinia pseudotuberculosis. It is produced by the strain of Agrobacterium vitis and Nitrosomonas europeae. Alternative Names: C8-HSL; OHL; N-Octanoyl-L-homoserine lactone; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide; HTF. Grades: >99% by HPLC. CAS No. 147852-84-4. Molecular formula: C12H21NO3. Mole weight: 227.30. | |
| Octapeptin C1 | It is a peptide antibiotic produced by the strain of Bacillus circulans 333-25. It has anti-gram-positive and gram-negative bacteria activity, but no effect on pseudomonas aeruginosa. It inhibits E. coli and Klebsiella pneumoniae with IC50 of 0.95 mg/kg (Mice, subcutaneous). Alternative Names: Antibiotic 333-25; Octapeptin A1, 1-(N(sup 2)-(3-hydroxy-6-methyl-1-oxooctyl)-D-2,4-diaminobutanoic acid)-4-D-phenylalanine-; N2-[N2-(3-Hydroxy-6-methyl-1-oxooctyl)-D-DAB-]cyclo[L-DAB*-L-DAB-D-Phe-L-Leu-L-DAB-L-DAB-L-Leu-]. CAS No. 59217-95-7. Molecular formula: C50H87N13O10. Mole weight: 1030.31. | |
| O-Demethylpaulomycin A | O-Demethylpaulomycin A is a quinone antibiotic produced by Streptomyces paulus. It has the effect of anti-gram-positive bacteria, and its activity is lower than that of Pauloycin. Alternative Names: 5-[6-(acetyloxymethyl)-4-[4,5-dihydroxy-6-methyl-5-[1-(2-methylbutanoyloxy)ethyl]oxan-2-yl]oxy-3-hydroxy-5-[(E)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylic acid, 5-(6-O-acetyl-3-O-(2,6-dideoxy-4-C-((S(S))-1-(2-methyl-1-oxobutoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-4-O-((Z)-2-isothiocyanato-1-oxo-2-butenyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-, (S)-. CAS No. 113603-74-0. Molecular formula: C33H44N2O17S. Mole weight: 772.77. | |
| O-Demethylpaulomycin B | O-Demethylpaulomycin B is a quinone antibiotic produced by Streptomyces paulus. It has the effect of anti-gram-positive bacteria, and its activity is lower than that of Pauloycin. Alternative Names: 5-[6-(acetyloxymethyl)-4-[4,5-dihydroxy-6-methyl-5-[1-(2-methylpropanoyloxy)ethyl]oxan-2-yl]oxy-3-hydroxy-5-[(E)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylic acid, 5-(6-O-acetyl-3-O-(2,6-dideoxy-4-C-((S)-1-(2-methyl-1-oxopropoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-4-O-(2-isothiocyanato-1-oxo-2-butenyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-, (S)-. CAS No. 113592-08-8. Molecular formula: C32H42N2O17S. Mole weight: 758.74. | |
| O-Desulfo Micafungin | O-Desulfo Micafungin is an impurity of caspofungin or micafungin. Micafungin is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. Alternative Names: Micafungin (m1); Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)-; 1-((4R,5R)-4,5-Dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)pneumocandin A0. CAS No. 539823-80-8. Molecular formula: C56H71N9O20. Mole weight: 1190.23. | |
| Odoratisol A | Odoratisol A is a lignan isolated from the aril of Myristica fragrans Houtt. Alternative Names: 2,6-dimethoxy-4-[(2S,3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol. Grades: >98%. CAS No. 891182-93-7. Molecular formula: C21H24O5. Mole weight: 356.418. | |
| Ofloxacin | Ofloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic. It has antimicrobial activity. It can inhibit DNA gyrase, Topo II (topoisomerase II) and Topo IV (Topo II α). Uses: Anti-bacterial agents; anti-infective agents, urinary; nucleic acid synthesis inhibitors. Alternative Names: RS-10085; RS 10085; RS10085; DL-8280; DR-3355; ORF-28489; Ru-43280; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Ofloxacine; HOE-280; Exocin; Flobacin; Floxil; Floxin; Monoflocet; Ocuflox. Grades: >98%. CAS No. 82419-36-1. Molecular formula: C18H20FN3O4. Mole weight: 361.37. | |
| Oganomycin A | Oganomycin A is produced by the strain of Str. oganonensis Y-G 19Z. It is more stable than cephalosporin and resistant to gram-positive and negative bacteria. And it is more effective against gram-negative bacteria than gram-positive bacteria. CAS No. 75794-94-4. Molecular formula: C24H27N3O13S2. Mole weight: 629.61. | |
| Oganomycin B | Oganomycin B is produced by the strain of Str. oganonensis Y-G 19Z. It is more stable than cephalosporin and resistant to gram-positive and negative bacteria. And it is more effective against gram-negative bacteria than gram-positive bacteria. CAS No. 75794-96-6. Molecular formula: C24H27N3O10S. Mole weight: 549.55. | |
| Oidiolactone A | Oidiolactone A is a diterpenoid produced by Oidiodendron griseum CL37215. It inhibits LPS-induced IL-1β and TNF-α activity with IC50 values of 1.5 and 4.7 μmol/L. Alternative Names: PR-1388; PR 1388; PR1388. CAS No. 90578-11-3. Molecular formula: C17H20O6. Mole weight: 320.3. | |
| OJV-VI | OJV-VI is a compound of the steroidal saponins found in the roots of Liriope spicata. Alternative Names: 25(S)-Ruscogenin 1-O-[α-L-rhamnopyranosyl-(1→2)][β-D-xylopyranosyl-(1→3)]-β-D-fucopyranoside. Grades: >98%. CAS No. 125150-67-6. Molecular formula: C44H70O16. Mole weight: 855.02. | |
| Okadaic acid potassium salt | Okadaic acid potassium salt, originally derived from marine dinoflagellates, Prorocentrium sp., is a potent, cell permeable inhibitor of serine / threonine protein phosphatases. It inhibits protein phosphatase 1 (IC50 = 3-15 nM) and protein phosphatase 2A (IC50 = 0.1-1 nM). Alternative Names: 35-Demethyl-DTX 1 Potassium Salt. CAS No. 209266-79-5. Molecular formula: C44H68O13K. Mole weight: 844.10. | |
| Okicenone | Okicenone is originally isolated from Str. sp. KO-3599 and it has the effect of killing tumor cells. Alternative Names: 3,4-Dihydro-4,6,9-trihydroxy-8-methyl-1(2H)-anthracenone; 1(2H)-Anthracenone, 3,4-dihydro-4,6,9-trihydroxy-8-methyl-. Grades: >98 %. CAS No. 137018-54-3. Molecular formula: C15H14O4. Mole weight: 258.27. | |
| Okilactomycin | It is originally isolated from Str. griseoflavus subsp. zamamiensis. It can resist gram-positive bacteria and inhibit leukemic cells. Alternative Names: (3R,3aR,5R,6R,8R,11aS,14S,15aS)-3,3a,5,6,7,8,9,10,11,11a,14,15-Dodecahydro-3,6,8,14-tetramethyl-16-methylene-2,17-dioxo-3,5-ethano-2H-furo[2,3-o][2]benzoxacycloundecin-13-carboxylic acid; YP-02908L-A. Grades: >98%. CAS No. 111367-04-5. Molecular formula: C24H32O6. Mole weight: 416.51. | |
| Oleandrin | Oleandrin, also known as PBI-05204, is a lipid soluble cardiac glycoside with potential antineoplastic activity. Upon administration, oleandrin specifically binds to and inhibits the alpha3 subunit of the Na/K-ATPase pump in human cancer cells. This may inhibit the phosphorylation of Akt, upregulate MAPK, inhibit NF-kb activation and inhibit FGF-2 export and may downregulate mTOR thereby inhibiting p70S6K and S6 protein expression. All of this may lead to an induction of apoptosis. As cancer cells with relatively higher expression of the alpha3 subunit and with limited expression of the alpha1 subunit more sensitive to oleandrin, one may predict the tumor response to treatment with lipid-soluble cardiac glycosides such as oleandrin based on the tumors Na/K-ATPase pump protein subunit expression. Overexpression of the alpha3 subunit in tumor cells correlates with tumor proliferation. Uses: Anti-proliferative. Alternative Names: (3b,5b,16b)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Neriolin; Corrigen. Grades: >98%. CAS No. 465-16-7. Molecular formula: C32H48O9. Mole weight: 576.72. | |
| Oleficin | It is originally isolated from Str. sp. 461. It is resistant to gram-positive bacteria and effective against subcutaneous transplantation of Yoshida sarcoma. Alternative Names: 4-[15-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14,16-trimethyl-1-oxo-2,4,6,8,10,12-heptadecahexenyl]-2,5-dihydro-3-hydroxy-1-methyl-5-oxo-1H-pyrrole-2-propanoic acid; LS-136996. Grades: 95% by HPLC. CAS No. 12764-54-4. Molecular formula: C34H47NO9. Mole weight: 613.74. | |
| Oligomycin | Oligomycin, a mixture of A, B, and C Oligomycin isomers, has been found to be a macrolide compound and could exhibit effect in restraining mitochondrial ATP-synthase. It is isolated from Streptomyces diastatochromogenes. Uses: Used as a tool in cytochemistry. Alternative Names: RK3325000; Oligomycin A. CAS No. 1404-19-9. Molecular formula: C45H74O11. Mole weight: 791.06. | |
| Oligomycin A | Oligomycin A, an ATP synthase inhibitor and a macrolide antibiotic with fungicidal activity isolated from Streptomyces species, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. Alternative Names: Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-; (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione; MCH 32. Grades: >98%. CAS No. 579-13-5. Molecular formula: C45H74O11. Mole weight: 791.06. | |
| Oligomycin B | A minor component of the oligomycin complex isolated from selected strains of streptomyces; an inhibitor of mitochondrial F1F0-atpas; used as an eukaryotic ATP synthase inhibitor, induces apoptosis. Alternative Names: BRN 5705502. Grades: >95% by HPLC. CAS No. 11050-94-5. Molecular formula: C45H72O12. Mole weight: 805.04. | |
| Oligomycin C | A minor component of the oligomycin complex isolated from selected strains of streptomyces; an inhibitor of mitochondrial F1F0-atpas; used as an eukaryotic ATP synthase inhibitor, induces apoptosis. Alternative Names: 12-Deoxyoligomycin A. Grades: >95% by HPLC. CAS No. 11052-72-5. Molecular formula: C45H74O10. Mole weight: 775.06. | |
| Oligomycin D | Oligomycin D is a macrolide compound produced by Streptomyces, which can inhibit mitochondrial F1FO-ATPase. Alternative Names: Rutamycin; 26-demethyloligomycin A; A 272; RR 32705; Rutamycin A. Grades: >95% by HPLC. CAS No. 1404-59-7. Molecular formula: C44H72O11. Mole weight: 777.03. | |
| Oligomycin E | It is a minor metabolite from the oligomycin complex produced by several species of streptomyces. It exhibits weak antibacterial activity and is considerably weaker as an antifungal agent. Alternative Names: (1R,2'S,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28R,29R)-22-ethyl-5',6'-dihydro-7,11,14,15,28-pentahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone; 26-hydroxy-28-oxo-Oligomycin A; [1R-[1R*,4E,5'S*,6S*,6'S*(R*),7R*,8S*,10R*,11R*,12S*,14R*,15S*,16R*,18E,20E,22R*,25S*,27S*,28R*,29R*]]-22-Ethyl-5',6'-dihydro-7,11,14,15,28-pentahydroxy-6'-(2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone. Grades: >95% by HPLC. CAS No. 110231-34-0. Molecular formula: C45H72O13. Mole weight: 821.05. | |
| Olivanic acid | Olivanic acid is a β-lactam antibiotic produced by Str. olivaceus. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Alternative Names: Olivanicacid. CAS No. 64761-66-6. Molecular formula: C11H14N2O4S. Mole weight: 270.31. | |
| Olivetonide | Olivetonide. CAS No. 3734-54-1. Molecular formula: C14H16O4. Mole weight: 248.27. | |
| Olivetonide dimethylether | Olivetonide dimethylether. | |
| Olivetoric acid | It occurs in lichens and forms a purplish red color with a solution of ferric chloride. Mainly used in chemical research. Alternative Names: Benzoic acid, 2,4-dihydroxy-6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; beta-Resorcylic acid, 6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-[2-(2-Oxoheptyl)-4,6-dihydroxybenzoyloxy]-6-pentylsalicylic acid; 2,4-Dihydroxy-6-(2-oxoheptyl)benzoic acid 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4,6-Dioxy-2-(β-oxo-n-heptyl)-benzoesaeure-(5-oxy-4-carboxy-3-n-amyl-phenylester); β-Resorcylic acid, 6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester. Grades: 99%. CAS No. 491-47-4. Molecular formula: C26H32O8. Mole weight: 472.53. | |
| Olivomycin | Olivomycin is an antitumor antibiotic produced by Actinomyces (or Streptomyces) olivoreticuli. It is used for the treatment of testicular neoplasms, tonsillar tumors and reticulosarcoma with peripheral nodes. Alternative Names: Toyomycin R; Olivomicina; Olivomycinum. CAS No. 11006-70-5. Molecular formula: C45H64O21. Mole weight: 941. | |
| Olivomycin A | Olivomycin A is originally isolated from Str. olivoreticuli. It has strong activity against gram-positive bacteria and weak activity against gram-negative bacteria. Alternative Names: Olivomycin I; NSC-76411; Olivomycin D, 3(B)-O-(2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-alpha-L-arabino-hexopyranosyl)-. CAS No. 6988-58-5. Molecular formula: C58H84O26. Mole weight: 1197.27. | |
| OM-173αA | OM-173αA is a quinone bacterial metabolite originally isolated from Streptomyces hebeiensis, displaying antimicrobial activity. It selectively inhibits Dnmt3b and induces antiproliferative effects in different tumor cell lines. It is effective against Gram-positive bacteria, mycobacterium, yeast and fungus. Alternative Names: OM-173alphaA; Nanaomycin αA; Nanaomycin A methyl ester; Nanaomycin alphaA; Antibiotic OM 173αA; (1S-trans)-3,4,5,10-Tetrahydro-9-hydroxy-1-methyl-5,10-dioxo-1H-naphtho[2,3-c]pyran-3-acetic Acid Methyl Ester. Grades: ≥95%. CAS No. 58286-56-9. Molecular formula: C17H16O6. Mole weight: 316.31. | |
| OM-173αB | OM-173αB is a quinone bacterial metabolite originally isolated from Streptomyces hebeiensis, displaying antimicrobial activity. It is effective against mycoplasma and fungus. Alternative Names: OM173-alphaB. CAS No. 88293-08-7. Molecular formula: C17H18O7. Mole weight: 334.3. | |
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