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Phomaligol A
Phomaligol A is an antibacterial metabolite produced from marine-derived fungus Aspergillus flavus. Alternative Names: Butanoic acid, 2-methyl-, (1R,5R)-5-hydroxy-4-methoxy-1,5-dimethyl-2,6-dioxo-3-cyclohexen-1-yl ester, (2S)-. Grades: ≥98%. CAS No. 152204-32-5. Molecular formula: C14H20O6. Mole weight: 284.31.
Phomopsinamine
Phomopsinamine is a potent mycotoxin and an effective microtubule inhibitor produced by the fungus, Phomopsis leptostromiformis. Phomopsinamine is formed by hydrolysis of the dicarboxylic acid of phomopsin A. Alternative Names: Isoleucinamide, (βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-, cyclic (15→3)-ether, (2E)-; Phomopsinamine A; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-isoleucinamide, cyclic (15→3)-ether; (S)-N-((E)-1-amino-3-methyl-1-oxopent-2-en-2-yl)-1-((3R,4S,7S,10S,11S)-15-chloro-3-ethyl-16,11-dihydroxy-3-methyl-10-(methylamino)-6,9-dioxo-7-(prop-1-en-2-yl)-2-oxa-5,8-diaza-1(1,3)-benzenacycloundecaphane-4-carbonyl)-2,5-dihydro-1H-pyrrole-2-carboxamide. Grades: >95% by HPLC. CAS No. 89085-54-1. Molecular formula: C32H43ClN6O8. Mole weight: 675.17.
Phoslactomycin A
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Alternative Names: Propanoic acid, 2-methyl-, (1S,3R)-3-[(1Z,3Z,5R,7R,8R,9E)-8-(2-aminoethyl)-10-[(2S,3S)-3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl]-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrien-1-yl]cyclohexyl ester; Propanoic acid, 2-methyl-, 3-[8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl]cyclohexyl ester, [2S-[2a[1Z(1R*,3S*),3Z,5S*,7S*,8S*,9E],3a]]-; (+)-Phoslactomycin A. CAS No. 122856-25-1. Molecular formula: C29H46NO10P. Mole weight: 599.65.
Phoslactomycin B
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Alternative Names: (+)-Phoslactomycin B; 2H-Pyran-2-one, 6-[(1E,3R,4R,6R,7Z,9Z)-3-(2-aminoethyl)-10-cyclohexyl-3,6-dihydroxy-4-(phosphonooxy)-1,7,9-decatrien-1-yl]-5-ethyl-5,6-dihydro-, (5S,6S)-. CAS No. 122856-26-2. Molecular formula: C25H40NO8P. Mole weight: 513.56.
Phoslactomycin C
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Alternative Names: Phosphazomycin C1; Butanoic acid, 3-methyl-, 3-[8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl]cyclohexyl ester. CAS No. 122856-27-3. Molecular formula: C30H48NO10P. Mole weight: 613.67.
Phoslactomycin D
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Alternative Names: Pentanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-28-4. Molecular formula: C31H50NO10P. Mole weight: 627.70.
Phoslactomycin E
It is produced by the strain of Str. nigrescens. It is the main component, which has weak effect against gram-positive bacteria, but has strong effect against fungi. Alternative Names: Cyclohexanecarboxylic Acid, 3-(8-(2-Aminoethyl)-10-(3-Ethyl-3,6-Dihydro-6-Oxo-2H-Pyran-2-Yl)-5,8-Dihydroxy-7-(Phophonooxy)-1,3,9-Decatrienyl)Cyclohexyl Ester. CAS No. 122856-29-5. Molecular formula: C32H50NO10P. Mole weight: 639.71.
Phoslactomycin F
It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Alternative Names: Hexanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-30-8. Molecular formula: C32H52NO10P. Mole weight: 641.73.
Phosmidosine
It is produced by the strain of Str. sp. RK-16. It can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. It has antifungal effect. Alternative Names: Phosmidosine A; Adenosine, 7,8-dihydro-8-oxo-, 5'-(methyl(2-pyrrolidinylcarbonyl)phosphoramidate), (S)-; 5'-O-[Methoxy[[[(2S)-pyrrolidin-2α-yl]carbonyl]amino]phosphinyl]-7,8-dihydro-8-oxoadenosine; Adenosine, 7,8-dihydro-8-oxo-, 5'-[methyl N-[(2S)-2-pyrrolidinylcarbonyl]phosphoramidate]. CAS No. 134966-01-1. Molecular formula: C16H24N7O8P. Mole weight: 473.38.
Phosmidosine B
It is produced by the strain of Str. sp. RK-16. It can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. Alternative Names: Adenosine, 7,8-dihydro-8-oxo-, 5'-[hydrogen[(2S)-2-pyrrolidinylcarbonyl]phosphoramidate]; Adenosine, 7,8-dihydro-8-oxo-, 5'-[hydrogen (2-pyrrolidinylcarbonyl)phosphoramidate], (S)-. CAS No. 146425-23-2. Molecular formula: C15H22N7O8P. Mole weight: 459.35.
Phosmidosine C
It is produced by the strain of Str. sp. RK-16. Molecular formula: C11H17N6O7P. Mole weight: 376.26.
Phosphocreatine
Phosphocreatine. CAS No. 67-07-2.
Phyllosinol
It is produced by the strain of Phyllosticta sp. pH-A. It's an antifungal antibiotic. It has the same effect as Sphaeropsidin and Epoxydon. Alternative Names: Epoxydon; Epoxydone; (+)-Parasitenone; (+)-Epoxydon; NSC 93049; Antibiotic 212T2; 7-Oxabicyclo[4.1.0]hept-3-en-2-one, (1R,5R,6R)-; 7-Oxabicyclo[4.1.0]hept-3-en-2-one, [1R-(1alpha,5beta,6alpha)]-. Grades: 95%. CAS No. 24292-29-3. Molecular formula: C7H8O4. Mole weight: 156.14.
Physcion-1-O-β-D-glucoside
Physcion-1-O-β-D-glucoside is a diterpenoid compound. It is a by-product during the synthesis of Physcion 8-β-D-glucoside. Physcion 8-β-D-glucoside has been studied in research relating to the treatment of the glomerulonephritis. It is the glucoside of Physcion that is a natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew. Alternative Names: 9,10-Anthracenedione, 1-(β-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-; 1-(β-D-Glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-9,10-anthracenedione; Physcionin; 3-Methyl-6-methoxy-1,8-dihydroxyanthraquinone 1-glucoside; Physcion 1-O-β-D-glucopyranoside; Physcion 1-O-β-D-glucoside; Physcion 1-β-D-glucopyranoside. Grades: >98%. CAS No. 26296-54-8. Molecular formula: C22H22O10. Mole weight: 446.40.
Physciosporin
Physciosporin (PHY) is an effective secondary metabolite found in lichens and isolated from Pseudocyphellaria coriacea. It inhibits the motility of lung cancer cells. Alternative Names: 2-Chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid methyl ester; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2-chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-, methyl ester; methyl 8-chloro-10-formyl-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylate; Chlorgranulatin; Methyl 5-chlorovirensate. CAS No. 64662-25-5. Molecular formula: C19H15ClO8. Mole weight: 406.77.
Physodalic acid
It is a lichen depsidone isolated from Hypogymnia physodes. Alternative Names: 4-(acetyloxymethyl)-10-formyl-3,9-dihydroxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; CCRIS 5525; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 9-[(acetyloxy)methyl]-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-. CAS No. 90689-60-4. Molecular formula: C20H16O10. Mole weight: 416.33.
PI-083
PI-083 is a platelet aggregation inhibitor produced by Streptomyces matensis A-6621. It is active against gram-positive bacteria with MIC of 0.39-3.13 μg/mL. It inhibits platelet aggregation induced by ADP, Arachidonic Acid and collagen with MIC of 30.4, 1.9 and 3.8 μmol/L. It also inhibits KB cell growth with IC50 of 0.026 μmol/L. Alternative Names: PI 083; PI083. CAS No. 119341-57-0. Molecular formula: C43H50O16. Mole weight: 822.8.
PI-200
PI-200 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 3.8 x 10(-4) M. Alternative Names: PI 200; PI200. CAS No. 143605-57-6. Molecular formula: C17H26O2. Mole weight: 262.4.
PI-201
PI-201 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 7.1 x 10(-4) M. Alternative Names: PI 201; PI201. CAS No. 143605-56-5. Molecular formula: C17H28O3. Mole weight: 280.4.
Picfeltarraenin X
Picfeltarraenin X is a triterpenoid compound isolated from the herbs of Picria felterrae Lour. Picfeltarraenin X exhibits inhibitory effect against AChE. Alternative Names: (2beta,3alpha,9beta,10alpha,16alpha)-2-(beta-D-Glucopyranosyloxy)-20,24-epoxy-3,16-dihydroxy-9-methyl-19-norlanosta-5,23-diene-11,22-dione. Grades: >98%. CAS No. 1391826-61-1. Molecular formula: C36H54O11. Mole weight: 662.817.
Picloram
Picloram is a systemic herbicide used for general woody plant control. Grades: ≥95% by HPLC. CAS No. 1918-2-1. Molecular formula: C6H3Cl3N2O2. Mole weight: 241.46.
Picrolichenic acid
It is a 3-spirobenzofuran heterocyclic compound isolated from Variolaria amara. Alternative Names: 6-Hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentylspiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylic acid; Pikrolichenic acid; Spiro[benzofuran-3(2H),1'-[2,5]cyclohexadiene]-5-carboxylic acid, 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-; picrolichenin; NSC 43331; 6-hydroxy-2'-methoxy-2,4'-dioxo-4,6'-dipentyl-2H-spiro[benzofuran-3,1'-cyclohexane]-2',5'-diene-5-carboxylic acid. CAS No. 466-34-2. Molecular formula: C25H30O7. Mole weight: 442.50.
Picroside II
Picroside II is an iridoid compound isolated from Picrorhiza. Picroside II has potent anti-apoptotic activity against renal I/R injury. Uses: Anti-apoptotic. Alternative Names: (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside; β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-; 6-Vanilloylcatalpol; Ampicoside; kutkin II; Vanilloyl catalpol. Grades: >98%. CAS No. 39012-20-9. Molecular formula: C23H28O13. Mole weight: 512.46.
Picroside IV
Picroside IV is a compound of the iridoids found in the roots of Picrorhiza scrophulariiflora. Alternative Names: 6'-O-p-E-Coumaroylcatalpol; β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-[(2E)-3-(4-hydroxyphenyl)-2-propenoate]; ((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(((1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl (E)-3-(4-hydroxyphenyl)acrylate. Grades: >98%. CAS No. 211567-04-3. Molecular formula: C24H28O12. Mole weight: 508.48.
Piericidin B
It is produced by the strain of Str. mobaraensis 16-24. It has anti-fungal, gram-positive bacteria and insect effects, but also has weak anti-gram-negative bacteria effect. Alternative Names: Piericidin B1; (-)-Piericidin B1; 4-Pyridinol, 2,3-dimethoxy-6-(10-methoxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-5-methyl-, (S-(R*,R*-(all-E)))-; 4-Pyridinol, 2,3-dimethoxy-6-[(2E,5E,7E,9R,10R,11E)-10-methoxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5-methyl-. CAS No. 16891-54-6. Molecular formula: C26H39NO4. Mole weight: 429.59.
Pikromycin
Pikromycin is a macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. It is an inhibitor of Prolyl endopeptidase (PREP) and has an inhibitory effect on E. coli, S. aureus, B. subtilis and mycobacteria. Alternative Names: (3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradec-11-ene-2,4,10-trione; Albomycetin; Amaromycin; Antibiotic B 62169A; [3R-(3R*,5R*,6S*,7S*,9R*,11E,13S*,14R*)]-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradec-11-ene-2,4,10-trione; Picromycin. Grades: ≥95% by HPLC. CAS No. 19721-56-3. Molecular formula: C28H47NO8. Mole weight: 525.67.
Pilatin
It is produced by the strain of Flagelloscypha pilatii JK 322. Like Marasmic acid, it has inhibitory effects on bacteria and fungi, and has strong inhibitory effects on the incorporation of thymidin and ureidin into DNA and RNA in Ehrlich carcinoma ascites cells. It can cause frameshift mutations in Salmonella typhimuium TA98. Alternative Names: 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-3,5a-dihydroxy-7,7-dimethyl-4-formyl-1-oxo-3H,6H,3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3-alpha,3a-beta,5a-beta,6-alpha(E),8a-beta,9b-beta))-; 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-4-formyl-3,5a-dihydroxy-7,7-dimethyl-1-oxo-3H,6H-3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3alpha,3abeta,5abeta,6alpha(E),8abeta,9bbeta))-. CAS No. 119525-97-2. Molecular formula: C21H26O7. Mole weight: 390.43.
Pillaromycin A
It is produced by the strain of Str. flavovirens 65786. It has anti-mycobacteria, gram-positive bacteria and gram-negative bacteria effects, but the effect of anti-gram-negative bacteria is weak. It also has antitumor activity similar to colchicine. Alternative Names: 5(1H)-Naphthacenone, 2,4a,12,12a-tetrahydro-3-acetyl-4a-((tetrahyro-5-hydroxy-5(hydroxyacetyl)-6-methyl-2H-pyran-2-yl)oxy)-1,2,6,7-tetrahydroxy-, (1R-(1-alpha,2-alpha,4a-alpha(2S*,5S*,6S*),12a-alpha))-; 5(1H)-Naphthacenone,3-acetyl-2,4a,12,12a-tetrahydro-1,2,6,7-tetrahydroxy-4a-[[(2S,5S,6S)-tetrahydro-5-hydroxy-5-(hydroxyacetyl)-6-methyl-2H-pyran-2-yl]oxy]-, (1R,2S,4aR,12aR)-; NSC 102812. CAS No. 30361-37-6. Molecular formula: C28H30O11. Mole weight: 542.53.
Piloquinone
It is produced by the strain of Str. pilosus. It's a phenanthrene compound. It has inhibitory effect on mycobacterium and protozoa, but the effect is not strong. Alternative Names: 9,10-Phenanthrenedione, 1,8-dihydroxy-2-methyl-3-(4-methyl-1-oxopentyl)-; 1,8-Dihydroxy-2-methyl-3-(4-methylpentanoyl)-9,10-phenanthrenedione. CAS No. 25414-26-0. Molecular formula: C21H20O5. Mole weight: 352.38.
Pimecrolimus
Pimecrolimus is an immunomodulator of calcineurin inhibitors produced by Streptomyces. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: 33-epi-Chloro-33-desoxyascomycin; ASM-981; ASM981; ASM 981; SDZ ASM 981; SDZ-ASM 981; SDZ-ASM-981. Grades: >98%. CAS No. 137071-32-0. Molecular formula: C43H68ClNO11. Mole weight: 810.45.
Pimprinethine
Pimprinethine is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. Alternative Names: APHE-1. CAS No. 146426-35-9. Molecular formula: C13H12N2O. Mole weight: 212.25.
Pinastric acid
It is a derivative of pulvinic acid and isolated from a terrestrial lichen. It displays antitumour, antiviral and antimicrobial (both antibacterial and antifungal) activities. Alternative Names: 4'-Methoxyvulpinic acid; Pianstric acid; (αE)-α-Phenyl-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylideneacetic acid methyl ester; 2-Phenyl-2-[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester; Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester; α-[(2E)-3-Hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]benzeneacetic acid methyl ester; Benzeneacetic acid, α-[3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2(5H)-furanylidene]-, methyl ester, (αE)-; methyl (E)-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-phenylacetate; δ2(5H),α-Furanacetic acid, 3-hydroxy-4-(p-methoxyphenyl)-5-oxo-α-phenyl-, methyl ester. CAS No. 481-64-1. Molecular formula: C20H16O6. Mole weight: 352.34.
Pinselin
It is produced by the strain of Penicillium sp., Pen. amarum. It is a nitrogen-containing heterocyclic antibiotic. It has anti-yeast activity. Alternative Names: Pincelin; 9H-Xanthene-1-carboxylic acid, 2,8-dihydroxy-6-methyl-9-oxo-, methyl ester; Cassiollin; 1,7-Dihydroxy-8-methoxycarbonyl-3-methylxanthon. CAS No. 476-53-9. Molecular formula: C16H12O6. Mole weight: 300.26.
Pintulin
It is produced by the strain of Penicillium vulpinum F-4148. In in vitro test, it can inhibit P388, L 1210, HL-60, KB and other tumor cell lines with IC50 (μg/mL) of 0.8, 0.8, 0.8, 0.25, respectively. It has only very weak antibacterial activity against the microorganisms tested. Molecular formula: C14H12O5. Mole weight: 260.24.
Pioglitazone hydrochloride
Pioglitazone hydrochloride, a thiazolidinedione antidiabetic drug, is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor with Kis of 1.7, 11.8 and 32.1 μM for CYP2C8, CYP3A4 and CYP2C9, respectively. It is an agonist of the peroxisome proliferator-activated receptor γ. Uses: Hypoglycemic agents. Alternative Names: 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione Hydrochloride; AD-4833; Actos; U-72107A; 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride; NSC 758876; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, monohydrochloride. Grades: >98%. CAS No. 112529-15-4. Molecular formula: C19H20N2O3S.HCl. Mole weight: 392.90.
Pioglitazone Imino Impurity
An impurity of Pioglitazone which is a thiazolidinedione compound with antiinflammatory and antiarteriosclerotic effects. Alternative Names: Pioglitazone 2-Imine; 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-2-iminothiazolidin-4-one. Grades: > 95%. CAS No. 105355-26-8. Molecular formula: C19H21N3O2S. Mole weight: 355.46.
Pipacycline
A semi-synthetic tetracycline formed by a mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracyclin. It inhibits the formation of penicillinase, the enzyme that inactivates penicillin in bacteria. It is used in salt form with penicillin V for parenteral use. Alternative Names: Mepicycline; Pipacyclinum. Grades: >98% by HPLC. CAS No. 1110-80-1. Molecular formula: C29H38N4O9. Mole weight: 586.63.
Pipemidic acid
Pipemidic acid is a synthetic quinolone antibiotic agent as an ATP-sensitive K+ channel blocker. Uses: Atp-sensitive k+ channel blocker. Alternative Names: Deblaston; Pipram; Uromidin; RB 1489; RB-1489; RB1489. Grades: ≥95%. CAS No. 51940-44-4. Molecular formula: C14H17N5O3. Mole weight: 303.32.
Piperafizine A
It is a methylated diketopiperazine formed by the condensation of phenylalanine and is produced by many species in the genus Streptomyces. It exhibits little activity in vitro but potentiates vincristine antitumour potency. Alternative Names: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grades: >99% by HPLC. CAS No. 130603-59-7. Molecular formula: C19H16N2O2. Mole weight: 304.34.
Piperazinomycin
It is produced by the strain of Streptoverticillium olivoreticuli subsp. neoenacticus. It has anti-fungal, yeast, some mycobacterium effects, but no anti-bacterial effect. Alternative Names: (+)-piperazinomycin; 13-Oxa-4,20-diazatetracyclo[12.2.2.23,6.18,12]heneicosa-8,10,12(19),14,16,17-hexaen-11-ol, (3S,6S)-. CAS No. 83858-82-6. Molecular formula: C18H20N2O2. Mole weight: 296.36.
Piptamine
It is produced by the strain of Piptoporus sp. Lu 9-1. It has broad antibacterial spectrum, it inhibits Staphylococcus aureus, enterococcus faecalis, Bacillus subtilis, Escherichia coli, Candida albicans with MIC (μg/mL) of 0.78-6.25, 1.56, 1.00, 12.5, 6.25, respectively. Molecular formula: C23H41N. Mole weight: 331.58.
Pirarubicin
Pirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent. Alternative Names: Theprubicin; CGH-869; CGH 869; CGH869. Grades: >98%. CAS No. 72496-41-4. Molecular formula: C32H37NO12. Mole weight: 627.64.
Pirarubicin hydrochloride
Pirarubicin Hydrochloride is an analogue of the anthracycline anti-neoplastic doxorubicin, which is an inhibitor of Topo II. It intercalates into DNA and interacts with topoisomerase II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. It is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines. Uses: Antineoplastic agents. Alternative Names: THP Hydrochloride. Grades: >98%. CAS No. 95343-20-7. Molecular formula: C32H38ClNO12. Mole weight: 664.10.
Pironetin
Pironetin is a plant growth regulator produced by Streptomyces sp. NK10958. Alternative Names: PA 48153C. CAS No. 151519-02-7. Molecular formula: C19H32O4. Mole weight: 324.5.
Pittosapogenin
Pittosapogenin is a triterpenoid compound. CAS No. 15399-43-6. Molecular formula: C30H50O6. Mole weight: 506.71.
Plactin A
Plactin A is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Molecular formula: C32H52N8O6. Mole weight: 644.80.
Plactin B
Plactin B is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Alternative Names: Plastin B. Molecular formula: C32H52N8O6. Mole weight: 644.80.
Plactin C
Plactin C is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Alternative Names: cyclo(-D-Val-L-Leu-D-alloIle-L-Phe-D-Arg-). Molecular formula: C32H52N8O5. Mole weight: 628.80.
Plactin D
Plactin D is a cyclic pentapeptide physiologically active substance produced by the fungus F165. It can promote the dissolution of fibrinolytic protein. Alternative Names: Plastin D; cyclo(-D-Val-L-Leu-D-Leu-L-Phe-D-Arg-). Molecular formula: C32H52N8O5. Mole weight: 628.80.
Planaic acid
It is produced by the strain of Lecidea plana and L.lithophila. Alternative Names: Plana acid; Planasaeure; 2-Methoxy-4-(2,4-dimethoxy-6-pentylbenzoyloxy)-6-pentylbenzoic acid. CAS No. 5366-7-4. Molecular formula: C27H36O7. Mole weight: 472.57.
Plantainoside D
Plantainoside D is a natural compound of the sesquiterpenoid class. Alternative Names: 2-(3,4-Dihydroxyphenyl)ethyl 3-O-beta-D-glucopyranosyl-beta-D-glucopyranoside 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]; Isoplantamajoside. Grades: >98%. CAS No. 147331-98-4. Molecular formula: C29H36O16. Mole weight: 640.59.
Platencin
Platencin is a broad-spectrum Gram-positive antibiotic produced by Streptomyces. Platencin is an effective antibiotic against FabF and FabH proteins. No toxicity was observed. Grades: >99% by HPLC. CAS No. 869898-86-2. Molecular formula: C24H27NO6. Mole weight: 425.47.
Platenomycin C3
Platenomycin C3 is a macrolide antibiotic produced by Str. platensis subsp. malvinus MCRL-0388 (FERM-P289). Activity against gram-positive bacteria. Alternative Names: Maridomycin I; Turimycin EP5; Antibiotic B 5050A; Antibiotic yl-704C3. Grades: >98%. CAS No. 35908-44-2. Molecular formula: C43H71NO16. Mole weight: 858.02.
Platensimycin
Platensimycin is a broad spectrum, gram-positive antibiotic produced by strains of streptomyces platensis. It inhibits bacterial growth by selectively inhibiting the elongation enzyme, b-ketoacyl acyl carrier protein synthase (fabf) of the fatty acid synthesis pathway. Alternative Names: (-)-Platensimycin. Grades: >95% by HPLC. CAS No. 835876-32-9. Molecular formula: C24H27NO7. Mole weight: 441.47.
Platycodin D3
Platycodin D3 has anti-hepatitis C virus (HCV) activity. It can be used as an expectorant in a variety of lung inflammatory diseases and regulate the production and secretion of mucin in the airway. Platycodin D3 is a triterpenoid compound and an inhibitor of NF-κB. Alternative Names: Olean-12-en-28-oic acid, 3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23,24-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,16α)-; 3-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-{[6-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy}-2,16,23,24-tetrahydroxy-28-oxoolean-12-en-28-yl]-α-L-arabinopyranose. Grades: >98%. CAS No. 67884-03-1. Molecular formula: C63H102O33. Mole weight: 1387.46.
Platycoside E
Platycoside E is a triterpenoid compound. Alternative Names: Platycoside E; 237068-41-6; CHEBI:70449; HY-N3522; AKOS040735041; MS-32197; CS-0023701; Q27138787. Grades: >98%. CAS No. 237068-41-6. Molecular formula: C69H112O38. Mole weight: 1549.62.
Platycoside G1
Platycoside G1 is a triterpenoid compound found in the roots of Platycodon grandiflorum. Alternative Names: Deapi-platycoside E. Grades: >98%. CAS No. 849758-42-5. Molecular formula: C64H104O34. Mole weight: 1417.502.
Pleuromutilin
It is produced by the strain of Drosophila subatrata. It is mainly anti-gram-positive bacterial activity. Alternative Names: Drosophilin B; Drosopholin B; Mutilin 14-glycolate; (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-hydroxyacetate; Valnemulin impurity E; Glycolic acid, 8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopentacycloocten-1(4H)-one; antibiotic bc757. Grades: >95%. CAS No. 125-65-5. Molecular formula: C22H34O5. Mole weight: 378.50.
Plumieride
Plumieride is isolated from the herb of Himatanthus fallax. It shows strong fungitoxicity against some dermatophytes. Alternative Names: Agoniadin. Grades: 98%. CAS No. 511-89-7. Molecular formula: C21H26O12. Mole weight: 470.42.
Pluracidomycin A1
Pluracidomycin A1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Alternative Names: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 7-oxo-3-sulfo-6-(1-(sulfooxy)ethyl)-, (5R-(5alpha,6beta(S*)))-; Pluracidomycin; Pluracidomycin A; SF 2103 A. Grades: >98%. CAS No. 82138-64-5. Molecular formula: 9H11NO10S2. Mole weight: 357.31.
Pluracidomycin B
Pluracidomycin B is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. CAS No. 82138-65-6. Molecular formula: C11H13NO10S2. Mole weight: 383.35.
Pluracidomycin C1
Pluracidomycin C1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Alternative Names: Pluracidomycin C. CAS No. 82138-66-7. Molecular formula: C10H13NO10S2. Mole weight: 371.34.
Pluraflavin A
Pluraflavin A is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. Pluraflavin A has the effect of inhibiting the transcription of glucose-6-phosphatase gene and has good anti-proliferation activity on tumor cells. Molecular formula: C43H54N2O14. Mole weight: 822.89.
Pluraflavin C
Pluraflavin C is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C43H56N2O15. Mole weight: 840.91.
Pluraflavin E
Pluraflavin E is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C36H41NO14. Mole weight: 711.71.
Pluviatolide
Pluviatolide is a butyrolactone lignan first isolated from the Australian native plant, Zanthoxylum pluviatile. It has a variety of biological activities, including antioxidant, enzyme inhibitory effect and antispasmodic properties. Alternative Names: (-)-Pluviatolide; 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-; 3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one; 4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one; trans-Pluviatolide; (3R,4R)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one. Grades: ≥95% by HPLC. CAS No. 28115-68-6. Molecular formula: C20H20O6. Mole weight: 356.37.
PM-94128
PM-94128. Alternative Names: PM 94128; PM94128. CAS No. 182292-49-5. Molecular formula: C22H34N2O6. Mole weight: 422.5.
PM-Toxin A
PM-Toxin A is a toxin produced by Phyllosticta maydis. Alternative Names: PM Toxin A. CAS No. 88212-12-8. Molecular formula: C33H60O8. Mole weight: 584.8.
PM-Toxin B
PM-Toxin B is a toxin produced by Phyllosticta maydis. Alternative Names: PM Toxin B. CAS No. 87879-56-9. Molecular formula: C33H62O8. Mole weight: 586.8.
PM-Toxin C
PM-Toxin C is a toxin produced by Phyllosticta maydis. Alternative Names: PM Toxin C. CAS No. 87879-55-8. Molecular formula: C35H66O9. Mole weight: 630.9.