BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Quinolactacin A | Quinolactactin A is a quinolone fungal metabolite that inhibits TNF production induced by LPS in murine peritoneal macrophages. Alternative Names: (3S)-2,3-dihydro-4-methyl-3-(1-methylpropyl)-1H-pyrrolo[3,4-b]quinoline-1,9(4H)-dione. Grades: >95%. CAS No. 319917-25-4. Molecular formula: C16H18N2O2. Mole weight: 270.33. |  |
| Quinolactacin A1 | The dominant analogue of a family of quinolone metabolites produced by penicillium citrinum; inhibit acetylcholinesterase and TNF production. Alternative Names: (+)-Quinolactacin A1; (3R)-2,3-dihydro-4-methyl-3-[(1S)-1-methylpropyl]-1H-pyrrolo[3,4-b]quinoline-1,9(4H)-dione. Grades: >95% by HPLC. CAS No. 815576-68-2. Molecular formula: C16H18N2O2. Mole weight: 270.33. | |
| Quinolactacin A2 | Quinolactacin A2 is the dominant analogue of a family of quinolone metabolites produced by penicillium citrinum, inhibits acetylcholinesterase and TNF production. Alternative Names: ZINC14684865. Molecular formula: C16H18N2O2. Mole weight: 270.33. | |
| Quinomycin B | Quinomycin B is originally isolated from Str. sp. 732. It has a strong effect on gram-positive bacteria and HeLa cells, and also on some gram-negative bacteria. It also has a protective effect on mice inoculated with poliovirus. Alternative Names: BRN 1071167; Quinomycin A,4-(N-methylalloisoleucine)-8-(N-methylalloisoleucine). CAS No. 13602-52-3. Molecular formula: C53H68N12O12S2. Mole weight: 1129.31. | |
| Quinomycin C | Quinomycin C is originally isolated from Str. sp. 732. It has a strong effect on gram-positive bacteria and HeLa cells, and also on some gram-negative bacteria. It also has a protective effect on mice inoculated with poliovirus. Alternative Names: Antibiotic U 48160; BRN 1071168. Grades: >98%. CAS No. 11001-74-4. Molecular formula: C55H72N12O12S2. Mole weight: 1157.36. | |
| Quinovic acid 3-O-(6-deoxyglucoside) 28-O-glucosyl ester | Quinovic acid 3-O-(6-deoxyglucoside) 28-O-glucosyl ester is isolated from the vines of Uncaria tomentosa. Alternative Names: Quinovic acid 3-O-(6-deoxy-β-D-glucopyranoside) 28-O-β-D-glucopyranosyl ester; Quinovic acid 3-O-(6-deoxyglucoside) 28-O-glucosyl ester; Urs-12-ene-27,28-dioic acid, 3-[(6-deoxy-β-D-glucopyranosyl)oxy]-, 28-β-D-glucopyranosyl ester, (3β)-; 3-O-[β-D-Quinovopyranosyl]quinovic acid 28-β-D-glucopyranosyl ester; 3-O-β-D-Quinovopyranosylquinovic acid 28-O-β-D-glucopyranosyl ester. Grades: >95%. CAS No. 124727-10-2. Molecular formula: C42H66O14. Mole weight: 794.97. | |
| Quinovic acid 3-O-glucoside | Quinovic acid 3-O-glucoside is isolated from the herbs of Luculia pincia. Alternative Names: Quinovic acid 3-O-beta-D-glucoside;Quinovic acid 3-O-glucoside. Grades: 0.93. CAS No. 79955-41-2. Molecular formula: C36H56O10. Mole weight: 648.8. | |
| Quinupristin | Quinupristin is an antibiotic and usually used in combination with dalfopristin (The trade name is Synercid). It is active against Gram-positive bacteria through inhibiting protein synthesis of the cells, but not active against Gram-negative bacteria, so it needs to be given in combination with other antibacterials for mixed infections which also involve Gram-negative organisms. Uses: Semisynthetic depsipeptide type i streptogramin. an antibacterial agent. Alternative Names: N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(4-(dimethylamino)benzyl)-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-((((S)-quinuclidin-3-yl)thio)methyl)docosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1]oxa[4,7,10,13,16]pentaazacyclononadecin-9-yl)-3-hydroxypicolinamide; RP68888; RP57669; Antibiotic RP 57669; 4-[4-(Dimethylamino)-N-methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]methyl]-4-oxo-2-piperidine carboxylic acid] Virginiamycin S1. Grades: 95%. CAS No. 120138-50-3. Molecular formula: C53H67N9O10S. Mole weight: 1022.22. | |
| R1128 A | R1128 A is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 A for partially purified rat uterine cytosol receptor was 11 x 10(-7) M. Alternative Names: R1128A; R-1128A. CAS No. 135161-96-5. Molecular formula: C17H14O5. Mole weight: 298.29. | |
| R1128 B | R1128 B is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 B for partially purified rat uterine cytosol receptor was 1.2 x 10(-7) M. Alternative Names: R1128B; R-1128B. CAS No. 135161-97-6. Molecular formula: C18H16O5. Mole weight: 312.3. | |
| R1128 C | R1128 C is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 C for partially purified rat uterine cytosol receptor was 2.6 x 10(-7) M. Alternative Names: R1128C; R-1128C. CAS No. 135161-98-7. Molecular formula: C19H18O5. Mole weight: 326.3. | |
| R1128 D | R1128 D is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 D for partially purified rat uterine cytosol receptor was 2.7 x 10(-7) M. Alternative Names: R1128D; R-1128D. CAS No. 135161-99-8. Molecular formula: C19H18O5. Mole weight: 326.3. | |
| R162 | R162 is a potent, selective inhibitor of glutamate dehydrogenase 1 (GDH1) (Ki = 28.6 μM), with anti-cancer properties. It does not inhibit the activity of other NADPH enzymes such as 6-phosphogluconate dehydrogenase and fumarate hydratase. Alternative Names: R 162; R-162; 2-allyl-1-hydroxy-anthraquinone; 2-allyl-1-hydroxyanthra-9,10-quinone. CAS No. 64302-87-0. Molecular formula: C17H12O3. Mole weight: 264.28. | |
| R176502 | R176502 is a bafilolide metabolite with potent antiproliferative activity, which is produced by Micromonospora sp. JS1035. It inhibits proliferation of MCF-7, HT-29, K562/C1000 and Malme-3M cells with IC50 values of 1.29 ± 0.35, 0.61 ± 0.04, 9.29 ± 7.35, 7.96 ± 2.75 nmol/L. Alternative Names: R 176502. Molecular formula: C47H67NO13. Mole weight: 854. | |
| (R)-2-Hydroxymethylpropanoic acid | (R)-2-Hydroxymethylpropanoic acid. Alternative Names: (R)-3-HYDROXY-2-METHYLPROPIONIC ACID; (R)-2-HYDROXYMETHYLPROPANOIC ACID; PROPANOIC ACID, 3-HYDROXY-2-METHYL-, (R)-; (2R)-3-hydroxy-2-methyl-Propanoic acid; (R)-3-Hydroxyisobutyric acid. CAS No. 1910-47-0. Molecular formula: C4H8O3. Mole weight: 104.10. | |
| (R)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol | An intermediate used in the synthesis of Duloxetine, an antidepressant. CAS No. 116539-57-2. Molecular formula: C8H13NOS. Mole weight: 171.26. | |
| Rabelomycin | Rabelomycin is originally isolated from Str.olivaceus. Rabelomycin only works against gram-positive bacteria. Alternative Names: ZINC4654730. Molecular formula: C19H14O6. Mole weight: 338.31. | |
| Rabeprazole-[13C,d3] Sodium salt | Rabeprazole-[13C,d3] Sodium salt, is the labelled analogue of Rabeprazole, which is a medication that decreases stomach acid. Rabeprazole is a proton pump inhibitor used to suppress gastric acid production. Alternative Names: Rabeprazole 13C D3 Sodium salt; 2-[[[(4-(3-Methoxy-13C,d3)propoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Sodium Salt. Grades: 95% by CP; 98% atom D; 98% atom 13C. Molecular formula: C17[13C]H17D3N3NaO3S. Mole weight: 385.44. | |
| Racemomycin A | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Alternative Names: Streptothricin F; Yazumycin A; Streptothricin VI; Antibiotic S 15-1A; BRN 6031385; 2-((O-(Aminocarbonyl)-2-deoxy-2-((3,6-diamino-1-oxohexyl)amino)-beta-D-gulopyranosyl)amino)-1,3,5,6,7,7a-hexahydro-7-hydroxy-4H-imidazo(4,5-c)pyridin-4-one. Grades: >98%. CAS No. 3808-42-2. Molecular formula: C19H34N8O8. Mole weight: 502.52. | |
| Racemomycin B | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Alternative Names: Streptothricin D; Antibiotic OP 2C; 2-{[(3S)-3-amino-6-{[(3S)-3-amino-6-{[(3S)-3,6-diaminohexanoyl]amino}hexanoyl]amino}hexanoyl]amino}-4-O-carbamoyl-2-deoxy-N-[(3aS,7R,7aS)-7-hydroxy-4-oxooctahydro-2H-imidazo[4,5-c]pyridin-2-ylidene]-beta-D-gulopyranosylamine. Grades: >98%. CAS No. 3776-37-2. Molecular formula: C31H58N12O10. Mole weight: 758.86. | |
| Racemomycin C | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Alternative Names: Streptothricin E; Yazumycin C; Antibiotic S 15-1B; 2-((O-(Aminocarbonyl)-2-((3-amino-6-((3,6-diamino-1-oxohexyl)amino)-1-oxohexyl)amino)-2-deoxy-beta-D-gulopyranosyl)amino)-1,3a,5,6,7,7a-hexahydro-7-hydroxy-4H-imidazo(4,5-c)pyridin-4-one; BRN 4286375. CAS No. 3776-38-3. Molecular formula: C25H46N10O9. Mole weight: 630.69. | |
| Racemomycin D | It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Alternative Names: Streptothricin C; Antibiotic OP 2D. CAS No. 3776-36-1. Molecular formula: C37H70N14O11. Mole weight: 887.04. | |
| Racemomycin E | Racemomycin E is an N-glycoside antibiotic produced by various bacteria such as Streptomyces lavendulae. It has anti-gram-positive bacteria, negative bacteria, mycobacteria and anti-fungal activity. Alternative Names: Streptothricin B; A 53930C. CAS No. 3484-68-2. Molecular formula: C43H82N16O12. Mole weight: 1015.21. | |
| Raddeanoside 20 | Raddeanoside 20 is a triterpenoid compound isolated from the rhizomes of Anemone raddeana Regel. Alternative Names: (4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-6a-(hydroxymethyl)-10-[(2S,3R,4S,5S)-4-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,2,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Grades: >98%. CAS No. 335354-79-5. Molecular formula: C47H76O17. Mole weight: 913.108. | |
| Radicinin | Radicinin is produced by the strain of Curvularia lunata IAM-18010. It has anti-bacterial effect, but its activity is weak. Alternative Names: Stemphylone; NSC 118343; 2,3-Dihydro-3-alpha-hydroxy-2-beta-methyl-7-propenyl-4H,5H-pyrano(4,3-b)pyran-4,5-dione. CAS No. 10088-95-6. Molecular formula: C12H12O5. Mole weight: 236.22. | |
| RAF-709 | RAF-709 is a novel Raf kinase inhibitor used for the treatment of non-small cell lung cancer (NSCLC). Uses: The treatment of nsclc. Alternative Names: N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide; RAF709; RAF-709; RAF 709. Grades: 98%. CAS No. 1628838-42-5. Molecular formula: C28H29F3N4O4. Mole weight: 542.56. | |
| Rakicidin A | Rakicidin A is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 40 μg/mL. Molecular formula: C32H54N4O7. Mole weight: 606.79. | |
| Ramalinolic acid | Ramalinolic acid. Alternative Names: Benzoic acid, 2,4-dihydroxy-3-[(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy]-6-pentyl-; 2,4-Dihydroxy-3-(2-hydroxy-4-methoxy-6-propyl-benzoyloxy)-6-pentyl-benzoesaeure; Ramalinolsaeure. CAS No. 552-56-7. Molecular formula: C23H28O8. Mole weight: 432.46. | |
| Ramulosin | It is produced by the strain of Pestalotia ramulosa NRRL 2826. Ramulosin has an antifungal effect and inhibits the germination of fungal meristems. Alternative Names: Ramulosine; NSC-112906; Ramulosin, (+)-; (3S,4AR)-8-hydroxy-3-methyl-3,4,4A,5,6, 7-hexahydro-1h-isochromen-1-one. CAS No. 29914-01-0. Molecular formula: C10H14O3. Mole weight: 182.22. | |
| Rancinamycin III | Rancinamycin III is an antibiotic that has antibacterial properties originally isolated from Str. lincolnensis. Alternative Names: SCHEMBL16431322. Grades: >97%. CAS No. 60925-60-2. Molecular formula: C7H10O5. Mole weight: 174.15. | |
| Rapanone | Rapanone is found in Embelia laeta. Alternative Names: 2,5-Dihydroxy-3-tridecyl-2,5-cyclohexadiene-1,4-dione. Grades: > 95%. CAS No. 573-40-0. Molecular formula: C19H30O4. Mole weight: 322.44. | |
| Rasfonin | Rasfonin is a fungal metabolite that has been found in Talaromyces sp. 3656-A1. It is a Ras-dependent apoptosis inducer that induces apoptosis in Ras-dependent cells such as Ba/F3-V12 cells. Alternative Names: (-)-Rasfonin; (2E,4E,6S)-8-hydroxy-6-(hydroxymethyl)-4-methyl-2,4-octadienoic acid, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester. Grades: >95%. CAS No. 303156-68-5. Molecular formula: C25H38O6. Mole weight: 434.56. | |
| Rebaudioside D | Rebaudioside D is extracted from the leaves of Stevia rebaudiana Bertoni. It is a potential sweetener. It showed similar stability when exposed to simulated stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected from the cecum. Alternative Names: (4a)-13-[(O-b-D-Glucopyranosyl-(1,2)-O-[b-D-glucopyranosyl-(1,3)]-b-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid 2-O-b-D-glucopyranosyl-b-D-glucopyranosyl ester; Reb D; Kaur-16-en-18-oic acid, 13-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]-, 2-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester, (4α)-. Grades: >98%. CAS No. 63279-13-0. Molecular formula: C50H80O28. Mole weight: 1129.15. | |
| Rebaudioside I | Rebaudioside I, a plant-derived non-caloric sweetener extracted from Stevia rebaudiana leaves, has been widely adopted in food and beverage industries as a sugar supplement. Beyond its sweetness, this compound demonstrates tremendous potential for managing type 2 diabetes, by enhancing insulin secretion and improving glucose tolerance. Evidence also suggests that rebaudioside I may possess both anti-inflammatory and anti-tumor properties, making it a promising candidate for therapeutic applications. Alternative Names: Kaur-16-en-18-oic acid, 13-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]-, 3-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester, (4α)-; Reb I. CAS No. 1220616-34-1. Molecular formula: C50H80O28. Mole weight: 1129.15. | |
| Reblastatin | Reblastatin is an Ansa antibiotic produced by Streptomyces hygroscopicus subsp. hygroscopicus SANK 61995 and is a reduction product of Geldanamycin. It is a cell cycle inhibitor that can inhibit cell proliferation. The IC50 for human mesenchymal lymphoma U-93 is 0.43 μg/mL, and the reference geldanamycin is 0.0011 μg/mL. Molecular formula: C29H44N2O8. Mole weight: 548.67. | |
| Reductiline | Reductiline is a pyrrole derivative produced by Streptomyces orientalis Y-1336. It has anti-Gram-positive bacteria and weak anti-fungal, virus and tumor activity. Alternative Names: 2-Propenamide, N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-3-[1-[3-(methylthio)propyl]-1H-pyrrol-3-yl]-, (E)-; Antibiotic AIS 2M3. CAS No. 85145-25-1. Molecular formula: C16H20N2O3S. Mole weight: 320.41. | |
| Reductiomycin | Reductiomycin is produced by the strain of Str. griseorubiginosus S551. It can resist gram-positive bacteria, fungi and some yeast. It also inhibits the proliferation of chicken Newcastle disease virus. Alternative Names: AM 6201; Alkaloid AM 6201; Antibiotic S 551II; Antibiotic AM 6201; BRN 4525860; (E)-4-(3-((2-hydroxy-5-oxocyclopent-1-en-1-yl)amino)-3-oxoprop-1-en-1-yl)-2,3-dihydrofuran-2-yl acetate. CAS No. 68748-55-0. Molecular formula: C14H15NO6. Mole weight: 293.27. | |
| Repotrectinib | TPX-0005 is an orally available and potent ATP-competitive inhibitor of ALK/ROS1/TRK (IC50= 5.3 nM for SRC, IC50= 1.01 nM, 1.26 nM and 1.08 nM for mutant ALKs including WT ALK, ALK G1202R and ALK L1196M, respectively). Alternative Names: TPX-0005; TPX 0005; TPX0005. CAS No. 1802220-02-5. Molecular formula: C18H18FN5O2. Mole weight: 355.37. | |
| RES-1149-1 | RES-1149-1 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 1.5 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| RES-1149-2 | RES-1149-2 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 20 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| RES-1214-1 | RES-1214-1 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 1.5 μmol/L. Molecular formula: C17H16O8. Mole weight: 348.3. | |
| RES-1214-2 | RES-1214-2 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 20 μmol/L. Molecular formula: C17H15ClO8. Mole weight: 382.7. | |
| RES-701-1 | RES-701-1 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Uses: Endothelin receptor antagonists. Alternative Names: GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP; GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP). Grades: 95%. CAS No. 151308-34-8. Molecular formula: C103H115N23O23. Mole weight: 2043.16. | |
| RES-701-2 | RES-701-2 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Molecular formula: C103H115N23O24. Mole weight: 2059.15. | |
| Reserpiline | Reserpiline is an indole alkaloid that has been found in R. tetraphylla. It is an antipsychotic, antiparasitic and hypotensive agent. Alternative Names: Methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate; Elliptamine; Reserpilin; (-)-Reserpiline; (4S,4aS,13bR,14aS)-4a,5,7,8,13,13b,14,14a-octahydro-10,11-dimethoxy-4-methyl-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylic acid, methyl ester; methyl (4S,4aS,13bR,14aS)-10,11-dimethoxy-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate. Grades: >95% by HPLC. CAS No. 131-02-2. Molecular formula: C23H28N2O5. Mole weight: 412.48. | |
| Resinone | Resinone is a bioactive chemical. Alternative Names: Lup-20(29)-en-3-one, 16-hydroxy-, (16β)-; 16-Hydroxylup-20(29)-en-3-one; Lup-20(29)-en-3-one, 16-hydroxy-, (16beta)-; (1R,3aS,4S,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-4-hydroxy-3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one; 16β-Hydroxylup-20(29)-en-3-one. Grades: >98%. CAS No. 43043-12-5. Molecular formula: C30H48O2. Mole weight: 440.70. | |
| Resistoflavine | A rare, boat-shaped, pentacyclic polyketide isolated from several species of streptomyces; exhibits weak antibacterial activity against gram-positive and gram-negative bacteria; exhibits potent cytotoxic activity against tumour cell lines in vitro; inhibits growth, and nucleic acid and protein synthesis in bacillus subtilis. Alternative Names: Resistoflavin; BRN 2491848; (-)-3,5,7,11b-Tetrahydroxy-1,1,9-trimethyl-2H-benzo(cd)pyrene-2,6,10(1H,11bH)-trione. Grades: >98% by HPLC. CAS No. 29706-96-5. Molecular formula: C22H16O7. Mole weight: 392.36. | |
| Resomycin A | It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin A showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H18O7. Mole weight: 382.36. | |
| Resomycin B | It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin B showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H16O6. Mole weight: 364.35. | |
| Resomycin C | It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin C showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H14O6. Mole weight: 362.33. | |
| Resorcinomycin A | Resorcinomycin A is produced by the strain of Streptoverticillum roseoverticillatum. It has strong anti-mycobacterium effect and weak anti-mycoplasma effect. Alternative Names: N-(alpha-Guanidino-3,5-dihydroxy-4-isopropylphenylacetyl)glycine; S-Resorcinomycin A; (S)-(2-((diaminomethylene)amino)-2-(3,5-dihydroxy-4-isopropylphenyl)acetyl)glycine. Grades: 95%. CAS No. 100234-70-6. Molecular formula: C14H20N4O5. Mole weight: 324.33. | |
| Resorcinomycin B | Resorcinomycin B is originally isolated from Streptoverticillum roseoverticillatum. Alternative Names: N-(alpha-Guanidino-3,5-dihydroxy-4-ethylphenylacetyl)glycine. CAS No. 100234-69-3. Molecular formula: C13H18N4O5. Mole weight: 310.31. | |
| Resormycin | It is originally isolated from Str. platensis MJ953-SF5. It has a strong herbicide effect, especially on the seeds of dicotyledonous plants. Resormycin also has anti-fungal action, resisting some plant pathogenic fungi, but not resisting bacteria and yeast. Molecular formula: C21H31ClN4O7. Mole weight: 486.95. | |
| Resorthiomycin | It is produced by the strain of Str. collinus 45H6 and it can inhibit L5178Y of leukemia cells in vitro. Alternative Names: 6-Acetyl-4-(3-hydroxybutyl)-2-methyl-5-methylthioresorcinol. CAS No. 126651-92-1. Molecular formula: C14H20O4S. Mole weight: 284.37. | |
| Respinomycin A1 | Respinomycin A1 is produced by the strain of Str. xanthocidicus RK-483 and it causes the differentiation of leukemic K-562 cells. Alternative Names: 13-[(6-Deoxy-3-C-methyl-2-O-methylhexopyranosyl)oxy]-23-(dimethylamino)-11,15,22-trihydroxy-12-methoxy-1,11-dimethyl-6,17-dioxo-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2, 4,7(16),8,14,18-hexaen-24-yl 3-amino-2,3,6-trideoxy-4-O-(6-deoxy-3-C-methyl-2-O-methylhexopyranosyl)-3-methylhexopyranoside. Grades: >99%. CAS No. 138843-19-3. Molecular formula: C51H72N2O20. Mole weight: 1033.12. | |
| Respinomycin A2 | Respinomycin A2 is produced by the strain of Str. xanthocidicus RK-483 and it causes the differentiation of leukemic K-562 cells. Alternative Names: 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-9,16-dione, 3,4,5,6,11,12,13,14-octahydro-5-((3-amino-2,3,6-trideoxy-4-O-(6-deoxy-3-C-methyl-2-O-methyl-alpha-mannopyranosyl)-3-C-methyl-beta-ribo-hexopyranosyl)oxy)-6,12-dimethyl-4-(dimethylamino)-13-methoxy-3,12,15-trihydroxy-, (2-alpha,3-beta,4-alpha,5-alpha,6-alpha,12-beta,13-alpha)-(+)-. CAS No. 151233-04-4. Molecular formula: C43H58N2O15. Mole weight: 842.92. | |
| Respirantin | Respirantin. Alternative Names: Cyclodepsipeptide 1. CAS No. 149598-67-4. Molecular formula: C37H53N3O13. Mole weight: 747.83. | |
| Reticulol | An isocoumarin metabolite produced by selected species of streptomyces. It is a potent inhibitor of cyclic nucleotide phosphodiesterase. It also causes dose-dependent inhibition of lung metastasis in the B16F10 melanoma model. Alternative Names: 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin; 6,8-Dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one; K 251-1; NSC 294978. Grades: >95% by HPLC. CAS No. 26246-41-3. Molecular formula: C11H10O5. Mole weight: 222.19. | |
| Reveromycin A | The dominant analogue of complex of spiroketals isolated from streptomyces sp. It is an inhibitor of the mitogenic activity of EGF and a G1 phase cell cycle inhibitor. It selectively inhibits isoleucyl-trna synthetase. It has anti-proliferation effect on human cell lines KB and K562, and has potent antifungal activity. Alternative Names: (-)-Reveromycin A; [2S-[2α(1E,3E),3β,6α[8S*(2E,4E,6R*,7R*,8E),9R*]]]-butanedioic acid mono[3-butyl-8-(9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl)-2-(4-carboxy-3-methyl-1,3-butadienyl)-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester; Butanedioic Acid Mono[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester. Grades: >99% by HPLC. CAS No. 134615-37-5. Molecular formula: C36H52O11. Mole weight: 660.79. | |
| Reveromycin B | Reveromycin B is a polyketide antibiotic isolated from Streptomyces, which can inhibit mitotic activity. Alternative Names: BDBM50217842; ZINC49871994. Grades: >98% by HPLC. CAS No. 144860-68-4. Molecular formula: C36H52O11. Mole weight: 660.79. | |
| Reveromycin C | Reveromycin C is a polyketide isolated from Streptomyces. It is an antibiotic inhibitor with mitotic activity that responds to EGF. Grades: >95% by HPLC. CAS No. 144860-69-5. Molecular formula: C37H54O11. Mole weight: 674.82. | |
| Reveromycin D | Reveromycin D is a bacterial metabolite isolated from Streptomyces. It inhibits EGF-induced mitotic activity in Balb/MK cells and has pH-dependent antifungal activity against Candida albicans. Grades: >95% by HPLC. CAS No. 144860-70-8. Molecular formula: C37H54O11. Mole weight: 674.82. | |
| Reynoutrin | Reynoutrin is a flavonoid glycoside isolated from the herbs of Saururus chinensis. Uses: Antioxidant. Alternative Names: Quercetin 3-beta-D-xylopyranoside. Grades: 95%. CAS No. 549-32-6. Molecular formula: C20H18O11. Mole weight: 434.35. | |
| (R)-(+)-HA-966 | (R)-(+)-HA-966 is a cell-permeable antagonist / partial agonist at the glycine site of the NMDA receptor. Alternative Names: R(+)-HA-966; 1-Hydroxy-3-amino-pyrrolidine-2-one, (R)-; Tocris-0281; (R)-(+)-3-Amino-1-hydroxypyrrolidin-2-one. Grades: ≥98% by HPLC. CAS No. 123931-04-4. Molecular formula: C4H8N2O2. Mole weight: 116.12. | |
| Rhizonic acid | Rhizonic acid. Alternative Names: Benzoic acid, 2-hydroxy-4-methoxy-3,6-dimethyl-; Rhizoninsaure; 6-Oxy-4-methoxy-2,5-dimethyl-benzoesaeure. Grades: ≥97%. CAS No. 479-26-5. Molecular formula: C10H12O4. Mole weight: 196.20. | |
| Rhodamine B hydrazide | Rhodamine B hydrazide is a water-soluble fluorescent probe used for the detection of copper, peroxynitrite, nitric oxide, hydrogen peroxide, glucose, diacetyl, and hemoglobin. Alternative Names: 2-amino-3',6'-bis(diethylamino)-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one. Grades: ≥98%. CAS No. 74317-53-6. Molecular formula: C28H32N4O2. Mole weight: 456.6. | |
| Rhodiocyanoside A | Rhodiocyanoside A is a cyanogenic glucoside found in the Rhodiola quadrifida with inhibitory activity against histamine. Alternative Names: (2Z)-4-(beta-D-glucopyranosyloxy)-2-methylbut-2-enenitrile; (2Z)-2-methyl-4-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}but-2-enenitrile. Grades: >98%. CAS No. 168433-86-1. Molecular formula: C11H17NO6. Mole weight: 259.258. | |
| Rhodionin | Rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs. Rhodionin showed inhibitory activity with IC50 values of 0.761 μM and 0.420 μM, respectively. Rhodionin was determined to be non-competitive inhibitors with Ki values of 0.769 μM and 0.535 μM. Alternative Names: Herbacetin 7-O-a-rhamnopyranoside; 7-[(6-Deoxy-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Herbacetin 7-O-α-L-rhamnopyranoside. Grades: >98%. CAS No. 85571-15-9. Molecular formula: C21H20O11. Mole weight: 448.38. | |
| Rhodirubin A | It is produced by the strain of Str. sp. ME505-HE1. Rhodirubin A has a strong anti-gram-positive bacteria effect, and also has an effect on Mycobacterium. It can also prolong the survival time of mice inoculated with leukemia L-1210. Alternative Names: 1-Hydroxy-MA-144-N1; MA144 N2; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-0-(2,6-dideoxy-4-O-((2S-(2-alpha,5-beta,6-beta))-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 64253-73-2. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| Rhodirubin B | It is produced by the strain of Str. sp. ME505-HE1. Rhodirubin B has a strong anti-gram-positive bacteria effect, and also has an effect on Mycobacterium. It can also prolong the survival time of mice inoculated with leukemia L-1210. Alternative Names: 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2-alpha,5-beta(2R*,5R*,6R*),6-beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 64502-82-5. Molecular formula: C42H55NO15. Mole weight: 813.88. | |
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